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ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [10]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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- Product number
- HPA020028 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA020028, RRID:AB_1856528
- Product name
- Anti-RYR2
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human RYR2, Gene description: ryanodine receptor 2 (cardiac), Alternative Gene Names: ARVC2, ARVD2, VTSIP, Validated applications: IHC, Uniprot ID: Q92736, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.2 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references CNP Promotes Antiarrhythmic Effects via Phosphodiesterase 2
Lamin A/C-dependent chromatin architecture safeguards naïve pluripotency to prevent aberrant cardiovascular cell fate and function
Calpain cleavage of Junctophilin-2 generates a spectrum of calcium-dependent cleavage products and DNA-rich NT1-fragment domains in cardiomyocytes
Human Atrial Fibrillation Is Not Associated With Remodeling of Ryanodine Receptor Clusters
Loss of CASK Accelerates Heart Failure Development
Junctophilin-2 tethers T-tubules and recruits functional L-type calcium channels to lipid rafts in adult cardiomyocytes
Long-term effects of empagliflozin on excitation-contraction-coupling in human induced pluripotent stem cell cardiomyocytes
IP3R-Mediated Compensatory Mechanism for Calcium Handling in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes With Cardiac Ryanodine Receptor Deficiency
Subtype-Directed Differentiation of Human iPSCs into Atrial and Ventricular Cardiomyocytes
Physiologic force-frequency response in engineered heart muscle by electromechanical stimulation
Cachorro E, Günscht M, Schubert M, Sadek M, Siegert J, Dutt F, Bauermeister C, Quickert S, Berning H, Nowakowski F, Lämmle S, Firneburg R, Luo X, Künzel S, Klapproth E, Mirtschink P, Mayr M, Dewenter M, Vettel C, Heijman J, Lorenz K, Guan K, El-Armouche A, Wagner M, Kämmerer S
Circulation Research 2023;132(4):400-414
Circulation Research 2023;132(4):400-414
Lamin A/C-dependent chromatin architecture safeguards naïve pluripotency to prevent aberrant cardiovascular cell fate and function
Wang Y, Elsherbiny A, Kessler L, Cordero J, Shi H, Serke H, Lityagina O, Trogisch F, Mohammadi M, El-Battrawy I, Backs J, Wieland T, Heineke J, Dobreva G
Nature Communications 2022;13(1)
Nature Communications 2022;13(1)
Calpain cleavage of Junctophilin-2 generates a spectrum of calcium-dependent cleavage products and DNA-rich NT1-fragment domains in cardiomyocytes
Weninger G, Pochechueva T, El Chami D, Luo X, Kohl T, Brandenburg S, Urlaub H, Guan K, Lenz C, Lehnart S
Scientific Reports 2022;12(1)
Scientific Reports 2022;12(1)
Human Atrial Fibrillation Is Not Associated With Remodeling of Ryanodine Receptor Clusters
Munro M, van Hout I, Aitken-Buck H, Sugunesegran R, Bhagwat K, Davis P, Lamberts R, Coffey S, Soeller C, Jones P
Frontiers in Cell and Developmental Biology 2021;9
Frontiers in Cell and Developmental Biology 2021;9
Loss of CASK Accelerates Heart Failure Development
Mustroph J, Sag C, Bähr F, Schmidtmann A, Gupta S, Dietz A, Islam M, Lücht C, Beuthner B, Pabel S, Baier M, El-Armouche A, Sossalla S, Anderson M, Möllmann J, Lehrke M, Marx N, Mohler P, Bers D, Unsöld B, He T, Dewenter M, Backs J, Maier L, Wagner S
Circulation Research 2021;128(8):1139-1155
Circulation Research 2021;128(8):1139-1155
Junctophilin-2 tethers T-tubules and recruits functional L-type calcium channels to lipid rafts in adult cardiomyocytes
Poulet C, Sanchez-Alonso J, Swiatlowska P, Mouy F, Lucarelli C, Alvarez-Laviada A, Gross P, Terracciano C, Houser S, Gorelik J
Cardiovascular Research 2021;117(1):149-161
Cardiovascular Research 2021;117(1):149-161
Long-term effects of empagliflozin on excitation-contraction-coupling in human induced pluripotent stem cell cardiomyocytes
Pabel S, Reetz F, Dybkova N, Shomroni O, Salinas G, Mustroph J, Hammer K, Hasenfuss G, Hamdani N, Maier L, Streckfuss-Bömeke K, Sossalla S
Journal of Molecular Medicine 2020;98(12):1689-1700
Journal of Molecular Medicine 2020;98(12):1689-1700
IP3R-Mediated Compensatory Mechanism for Calcium Handling in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes With Cardiac Ryanodine Receptor Deficiency
Luo X, Li W, Künzel K, Henze S, Cyganek L, Strano A, Poetsch M, Schubert M, Guan K
Frontiers in Cell and Developmental Biology 2020;8
Frontiers in Cell and Developmental Biology 2020;8
Subtype-Directed Differentiation of Human iPSCs into Atrial and Ventricular Cardiomyocytes
Kleinsorge M, Cyganek L
STAR Protocols 2020;1(1):100026
STAR Protocols 2020;1(1):100026
Physiologic force-frequency response in engineered heart muscle by electromechanical stimulation
Godier-Furnémont A, Tiburcy M, Wagner E, Dewenter M, Lämmle S, El-Armouche A, Lehnart S, Vunjak-Novakovic G, Zimmermann W
Biomaterials 2015;60
Biomaterials 2015;60
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Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Orthogonal validation
- Main image
- Experimental details
- Immunohistochemistry analysis in human heart muscle and liver tissues using HPA020028 antibody. Corresponding RYR2 RNA-seq data are presented for the same tissues.
- Sample type
- Human
- Protocol
- Protocol
