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- Antigen structure
- References [14]
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- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 12411-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12411-1-AP, RRID:AB_2268237
- Product name
- PI4KA antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated PI4KA antibody (Cat. #12411-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Heat shock-induced PI(4)P increase drives HSPA1A translocation to the plasma membrane in cancer and stressed cells through PI4KIII alpha activation.
Synaptic vesicle fusion promotes phosphatidylinositol 4-phosphate synthesis for efficient synaptic transmission.
Involvement of ribosomal protein L17 and Y-box binding protein 1 in the assembly of hepatitis C virus potentially via their interaction with the 3' untranslated region of the viral genome.
Targeting PI4KA sensitizes refractory leukemia to chemotherapy by modulating the ERK/AMPK/OXPHOS axis.
A phosphoinositide signalling pathway mediates rapid lysosomal repair.
Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.
Supercritical fluid chromatography-mass spectrometry enables simultaneous measurement of all phosphoinositide regioisomers.
Biallelic PI4KA variants cause a novel neurodevelopmental syndrome with hypomyelinating leukodystrophy.
Golgi-derived PI(4)P-containing vesicles drive late steps of mitochondrial division.
WNK1 promotes renal tumor progression by activating TRPC6-NFAT pathway.
A Forward Genetic Screen Targeting the Endothelium Reveals a Regulatory Role for the Lipid Kinase Pi4ka in Myelo- and Erythropoiesis.
Nrf-2-driven long noncoding RNA ODRUL contributes to modulating silver nanoparticle-induced effects on erythroid cells.
Signal peptidase complex subunit 1 participates in the assembly of hepatitis C virus through an interaction with E2 and NS2.
Host factors required for modulation of phagosome biogenesis and proliferation of Francisella tularensis within the cytosol.
Arce A, Altman R, Badolian A, Low J, Cuaresma AB, Halkia G, Keshet U, Fiehn O, Stahelin RV, Nikolaidis N
Cell stress & chaperones 2026 Feb;31(1):100130
Cell stress & chaperones 2026 Feb;31(1):100130
Synaptic vesicle fusion promotes phosphatidylinositol 4-phosphate synthesis for efficient synaptic transmission.
Yoshida T, Kawano H, Omi J, Hori T, Kobayashi Y, Saitoh N, Aoki J, Takamori S
Cell reports 2025 May 27;44(5):115634
Cell reports 2025 May 27;44(5):115634
Involvement of ribosomal protein L17 and Y-box binding protein 1 in the assembly of hepatitis C virus potentially via their interaction with the 3' untranslated region of the viral genome.
Liu J, Ito M, Liu L, Nakashima K, Satoh S, Konno A, Suzuki T
Journal of virology 2024 Jul 23;98(7):e0052224
Journal of virology 2024 Jul 23;98(7):e0052224
Targeting PI4KA sensitizes refractory leukemia to chemotherapy by modulating the ERK/AMPK/OXPHOS axis.
Jiang X, Huang X, Zheng G, Jia G, Li Z, Ding X, Lei L, Yuan L, Xu S, Gao N
Theranostics 2022;12(16):6972-6988
Theranostics 2022;12(16):6972-6988
A phosphoinositide signalling pathway mediates rapid lysosomal repair.
Tan JX, Finkel T
Nature 2022 Sep;609(7928):815-821
Nature 2022 Sep;609(7928):815-821
Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.
Li FL, Wu Z, Gao YQ, Bowling FZ, Franklin JM, Hu C, Suhandynata RT, Frohman MA, Airola MV, Zhou H, Guan KL
The EMBO journal 2022 Sep 1;41(17):e110698
The EMBO journal 2022 Sep 1;41(17):e110698
Supercritical fluid chromatography-mass spectrometry enables simultaneous measurement of all phosphoinositide regioisomers.
Shimanaka Y, Matsumoto K, Tanaka Y, Ishino Y, Ni S, Guan JL, Arai H, Kono N
Communications chemistry 2022 May 11;5(1):61
Communications chemistry 2022 May 11;5(1):61
Biallelic PI4KA variants cause a novel neurodevelopmental syndrome with hypomyelinating leukodystrophy.
Verdura E, Rodríguez-Palmero A, Vélez-Santamaria V, Planas-Serra L, de la Calle I, Raspall-Chaure M, Roubertie A, Benkirane M, Saettini F, Pavinato L, Mandrile G, O'Leary M, O'Heir E, Barredo E, Chacón A, Michaud V, Goizet C, Ruiz M, Schlüter A, Rouvet I, Sala-Coromina J, Fossati C, Iascone M, Canonico F, Marcé-Grau A, de Souza P, Adams DR, Casasnovas C, Rehm HL, Mefford HC, González Gutierrez-Solana L, Brusco A, Koenig M, Macaya A, Pujol A
Brain : a journal of neurology 2021 Oct 22;144(9):2659-2669
Brain : a journal of neurology 2021 Oct 22;144(9):2659-2669
Golgi-derived PI(4)P-containing vesicles drive late steps of mitochondrial division.
Nagashima S, Tábara LC, Tilokani L, Paupe V, Anand H, Pogson JH, Zunino R, McBride HM, Prudent J
Science (New York, N.Y.) 2020 Mar 20;367(6484):1366-1371
Science (New York, N.Y.) 2020 Mar 20;367(6484):1366-1371
WNK1 promotes renal tumor progression by activating TRPC6-NFAT pathway.
Kim JH, Hwang KH, Eom M, Kim M, Park EY, Jeong Y, Park KS, Cha SK
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Jul;33(7):8588-8599
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Jul;33(7):8588-8599
A Forward Genetic Screen Targeting the Endothelium Reveals a Regulatory Role for the Lipid Kinase Pi4ka in Myelo- and Erythropoiesis.
Ziyad S, Riordan JD, Cavanaugh AM, Su T, Hernandez GE, Hilfenhaus G, Morselli M, Huynh K, Wang K, Chen JN, Dupuy AJ, Iruela-Arispe ML
Cell reports 2018 Jan 30;22(5):1211-1224
Cell reports 2018 Jan 30;22(5):1211-1224
Nrf-2-driven long noncoding RNA ODRUL contributes to modulating silver nanoparticle-induced effects on erythroid cells.
Gao M, Zhao B, Chen M, Liu Y, Xu M, Wang Z, Liu S, Zhang C
Biomaterials 2017 Jun;130:14-27
Biomaterials 2017 Jun;130:14-27
Signal peptidase complex subunit 1 participates in the assembly of hepatitis C virus through an interaction with E2 and NS2.
Suzuki R, Matsuda M, Watashi K, Aizaki H, Matsuura Y, Wakita T, Suzuki T
PLoS pathogens 2013;9(8):e1003589
PLoS pathogens 2013;9(8):e1003589
Host factors required for modulation of phagosome biogenesis and proliferation of Francisella tularensis within the cytosol.
Akimana C, Al-Khodor S, Abu Kwaik Y
PloS one 2010 Jun 11;5(6):e11025
PloS one 2010 Jun 11;5(6):e11025
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human brain tissue were subjected to SDS PAGE followed by western blot with 12411-1-AP(PI4KA antibody) at dilution of 1:400
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The PI4KA antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human PI4KA. This antibody recognizes human,mouse,rat antigen. The PI4KA antibody has been validated for the following applications: ELISA, WB, IHC analysis.
