PB9985
antibody from Boster Biological Technology
Targeting: APOBEC3G
bK150C2.7, CEM15, dJ494G10.1, FLJ12740, MDS019
Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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Validation data
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- Product number
- PB9985 - Provider product page
- Provider
- Boster Biological Technology
- Product name
- Anti-APOBEC3G Antibody Picoband™
- Antibody type
- Polyclonal
- Description
- Polyclonal antibody for APOBEC3G detection. Host: Rabbit.Size: 100μg/vial. Tested applications: IHC-P. Reactive species: Human. APOBEC3G information: Molecular Weight: 46408 MW; Subcellular Localization: Cytoplasm. Nucleus. Cytoplasm, P-body. Mainly cytoplasmic. Small amount are found in the nucleus. During HIV-1 infection, virion-encapsidated in absence of HIV-1 VIF; Tissue Specificity: Expressed in spleen, testes, ovary and peripheral blood leukocytes and CD4+ lymphocytes. Also expressed in non-permissive peripheral blood mononuclear cells, and several tumor cell lines; no expression detected in permissive lymphoid and non-lymphoid cell lines. Exists only in the LMM form in peripheral blood-derived resting CD4 T-cells and monocytes, both of which are refractory to HIV-1 infection. LMM is converted to a HMM complex when resting CD4 T-cells are activated or when monocytes are induced to differentiate into macrophages. This change correlates with increased susceptibility of these cells to HIV-1 infection.
- Reactivity
- Human
- Host
- Rabbit
- Vial size
- 100μg/vial
- Concentration
- Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
- Storage
- At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquoted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
- Handling
- Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
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Supportive validation
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- Boster Biological Technology (provider)
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- Experimental details
- APOBEC3G was detected in paraffin-embedded sections of human pancreatic cancer tissues using rabbit anti- APOBEC3G Antigen Affinity purified polyclonal antibody (Catalog # PB9985) at 1 μg/mL. The immunohistochemical section was developed using SABC method (Catalog # SA1022).
- Additional image