Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Immunocytochemistry [1]
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Validation data
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- Product number
- ALX-804-555-C200 - Provider product page
- Provider
- Enzo Life Sciences
- Proper citation
- Enzo Life Sciences Cat#ALX-804-555-C200, RRID:AB_2052304
- Product name
- Presenilin 1 monoclonal antibody (APS 18)
- Antibody type
- Monoclonal
- Antigen
- Synthetic peptide
- Description
- Protein G affinity purified.
- Reactivity
- Human, Mouse, Rat, Simian
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- APS 18
- Vial size
- 200 μg
- Storage
- -20°C
- Handling
- Avoid freeze/thaw cycles.
Submitted references Analysis of presenilin 1 and presenilin 2 expression and processing by newly developed monoclonal antibodies.
Direct interaction of Alzheimer's disease-related presenilin 1 with armadillo protein p0071.
Abrogation of the presenilin 1/beta-catenin interaction and preservation of the heterodimeric presenilin 1 complex following caspase activation.
Diehlmann A, Ida N, Weggen S, Grünberg J, Haass C, Masters CL, Bayer TA, Beyreuther K
Journal of neuroscience research 1999 May 15;56(4):405-19
Journal of neuroscience research 1999 May 15;56(4):405-19
Direct interaction of Alzheimer's disease-related presenilin 1 with armadillo protein p0071.
Stahl B, Diehlmann A, Südhof TC
The Journal of biological chemistry 1999 Apr 2;274(14):9141-8
The Journal of biological chemistry 1999 Apr 2;274(14):9141-8
Abrogation of the presenilin 1/beta-catenin interaction and preservation of the heterodimeric presenilin 1 complex following caspase activation.
Tesco G, Kim TW, Diehlmann A, Beyreuther K, Tanzi RE
The Journal of biological chemistry 1998 Dec 18;273(51):33909-14
The Journal of biological chemistry 1998 Dec 18;273(51):33909-14
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Supportive validation
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- Enzo Life Sciences (provider)
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- Experimental details
- Immunocytochemistry using MAb to Presenilin 1 (APS 18) (Prod. No. ALX-804-555) shows endogenous presenilin 1 staining in Golgi and cellular vesicles in 4% paraformaldehyde fixed N2a cells.