Tissue expression
Cell line expression
Protein structure
RNF103
Ring finger protein 103hkf-1, KF1, ZFP103
The protein encoded by this gene contains a RING-H2 finger, a motif known to be involved in protein-protein and protein-DNA interactions. This gene is highly expressed in normal cerebellum, but not in the cerebral cortex. The expression of the rat counterpart in the frontal cortex and hippocampus was shown to be induced by elctroconvulsive treatment (ECT) as well as chronic antidepressant treatment, suggesting that this gene may be a molecular target for ECT and antidepressants. The protein is a ubiquitin ligase that functions in the endoplasmic reticulum-associated degradation pathway. Alternative splicing of this gene results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream CHMP3 (charged multivesicular body protein 3) gene. [provided by RefSeq, Oct 2011]
Top validated antibodies |
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Novus Biologicals | H00007844-M01 | Monoclonal |
WB
EL
BN
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Cusabio Biotech Co., Ltd | CSB-PA019815LA01HU | Polyclonal |
EL
ICC
IHC
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Biorbyt | orb1430 | Polyclonal |
EL
ICC
IHC
|
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Abnova Corporation | PAB8491 | 3 references | Polyclonal |
ICC
|
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antibodies-online | ABIN394611 | Monoclonal |
WB
IHC |
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Supportive data in Antibodypedia
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Recommended by provider