CABT-B11286

antibody from Creative Diagnostics

Targeting: RRM2B p53R2

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Antibody Data

Product number

CABT-B11286

Provider

Creative Diagnostics

Product name

Mouse anti-Human RRM2B monoclonal antibody, clone 7D2

Antibody type

Monoclonal

Description

This gene encodes the small subunit of a p53-inducible ribonucleotide reductase. This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates. The product of this reaction is necessary for DNA synthesis. Mutations in this gene have been associated with autosomal recessive mitochondrial DNA depletion syndrome, autosomal dominant progressive external ophthalmoplegia-5, and mitochondrial neurogastrointestinal encephalopathy. Alternatively spliced transcript variants have been described.[provided by RefSeq, Feb 2010]

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

7D2

Vial size

50 _g

Storage

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.