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Learn12476-1-AP
antibody from Proteintech Group
Targeting: SEPTIN4
ARTS, C17orf47, CE5B3, FLJ40121, H5, hCDCREL-2, hucep-7, MART, PNUTL2, SEPT4
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ELISAAntibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- 12476-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12476-1-AP, RRID:AB_2187151
- Product name
- Septin 4 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated Septin 4 antibody (Cat. #12476-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IP, WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Loss of cilia drives centriole clustering and elimination during mammalian spermatogenesis.
The TEX44-CPT1B axis regulates mitochondrial sheath assembly and fatty acid oxidation in sperm.
The role of SLC26A8 homozygous variants in male infertility and flagellum abnormalities.
TMEM232 is required for the formation of sperm flagellum and male fertility in mice.
Discovery of a septin-4 covalent binder with antimetastatic activity in a mouse model of melanoma.
A novel mutation in CFAP47 causes male infertility due to multiple morphological abnormalities of the sperm flagella.
Atorvastatin rescues vascular endothelial injury in hypertension by WWP2-mediated ubiquitination and degradation of ATP5A.
Septin4 Prevents PDGF-BB-induced HAVSMC Phenotypic Transformation, Proliferation and Migration by Promoting SIRT1-STAT3 Deacetylation and Dephosphorylation.
Septin4 as a novel binding partner of PARP1 contributes to oxidative stress induced human umbilical vein endothelial cells injure.
Chen JJ, Gong X, Mak M, Li FQ, Takemaru KI
bioRxiv : the preprint server for biology 2025 Dec 8;
bioRxiv : the preprint server for biology 2025 Dec 8;
The TEX44-CPT1B axis regulates mitochondrial sheath assembly and fatty acid oxidation in sperm.
Zhi E, Bai H, Ren C, Dong Y, Zhang J, Xu Y, Tan C, Pan Y, Zhou L, Li P, Tan Y, Zhou Y, Meng L, Xu J, Zhang Y, Xu S, Ji Z, Zhao L, Jiang M, Li Z, Yao C, Zhou Y, Wu J, Yang X, Liu S, Liu M
Nature communications 2025 Aug 23;16(1):7864
Nature communications 2025 Aug 23;16(1):7864
The role of SLC26A8 homozygous variants in male infertility and flagellum abnormalities.
Mao B, Zhang SS, Zhao LT, Huang HR, Ma FD, Shi WJ, Li S, Nie ZY, Xiao HD, Xie XD, Li PQ
Asian journal of andrology 2024 Sep 1;26(5):544-546
Asian journal of andrology 2024 Sep 1;26(5):544-546
TMEM232 is required for the formation of sperm flagellum and male fertility in mice.
Cai X, Zhang H, Kong S, Xu W, Zheng J, Wang N, He S, Li S, Shen Y, Wang K, Zhang Z, Cai H, Ma F, Bai S, Zhu F, Xiao F, Wang F
Cell death & disease 2024 Nov 8;15(11):806
Cell death & disease 2024 Nov 8;15(11):806
Discovery of a septin-4 covalent binder with antimetastatic activity in a mouse model of melanoma.
Blua F, Monge C, Gastaldi S, Clemente N, Pizzimenti S, Lazzarato L, Senetta R, Vittorio S, Gigliotti CL, Boggio E, Dianzani U, Vistoli G, Altomare AA, Aldini G, Dianzani C, Marini E, Bertinaria M
Bioorganic chemistry 2024 Mar;144:107164
Bioorganic chemistry 2024 Mar;144:107164
A novel mutation in CFAP47 causes male infertility due to multiple morphological abnormalities of the sperm flagella.
Liu M, Dai S, Zhang J, Yang Y, Shen Y, Liu H, Yang Y, Jiang C, Tian E
Frontiers in endocrinology 2023;14:1155639
Frontiers in endocrinology 2023;14:1155639
Atorvastatin rescues vascular endothelial injury in hypertension by WWP2-mediated ubiquitination and degradation of ATP5A.
Yin Z, You S, Zhang S, Zhang L, Wu B, Huang X, Lu S, Cao L, Zhang Y, Li D, Zhang X, Liu J, Sun Y, Zhang N
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Oct;166:115228
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Oct;166:115228
Septin4 Prevents PDGF-BB-induced HAVSMC Phenotypic Transformation, Proliferation and Migration by Promoting SIRT1-STAT3 Deacetylation and Dephosphorylation.
Zhang N, Zhang Y, You S, Tian Y, Lu S, Cao L, Sun Y
International journal of biological sciences 2020;16(4):708-718
International journal of biological sciences 2020;16(4):708-718
Septin4 as a novel binding partner of PARP1 contributes to oxidative stress induced human umbilical vein endothelial cells injure.
Zhang N, Zhang Y, Zhao S, Sun Y
Biochemical and biophysical research communications 2018 Feb 5;496(2):621-627
Biochemical and biophysical research communications 2018 Feb 5;496(2):621-627
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The SEPT4 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human SEPT4. This antibody recognizes human antigen. The SEPT4 antibody has been validated for the following applications: ELISA, WB analysis.
