Antibody data
- Antibody Data
- Antigen structure
- References [11]
- Comments [0]
- Validations [0]
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- Product number
- ABIN118028 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Macrophage Migration Inhibitory Factor (Glycosylation-Inhibiting Factor) (MIF) (AA 2-32) antibody
- Antibody type
- Polyclonal
- Antigen
- This IgY fraction antibody was prepared from eggs of chickens laid after repeated immunizations with a synthetic peptide corresponding to aa 2-32 of Human MIF conjugated to keyhole limpet hemocyanin (KLH). MIF is a proinflammatory cytokine that plays an important role in systemic inflammatory events.
- Description
- Multi-step process which includes selective precipitation and salt fractionation followed by extensive dialysis
- Reactivity
- Human
- Host
- Chicken/Avian
- Antigen sequence
P-M-F-I-V-N-T-N-V-P-R-A-S-V-P-D-G-F
-L-S-E-L-T-Q-Q-L-A-Q-A-T-G- Epitope
- AA 2-32
- Vial size
- 0.5 mg
- Concentration
- 5.0 mg/mL (by UV absorbance at 280 nm)
- Storage
- Store vial at 2-8°C prior to restoration. For extended storage mix with glycerol to 50% and then aliquot contents and freeze at -20°C or below. Centrifuge product if not completely clear after standing at room temperature. This product is stable for one month at 2-8°C as an undiluted liquid.
- Handling
- Avoid repeated freezing and thawing. Dilute only prior to immediate use
Submitted references Intracellular action of the cytokine MIF to modulate AP-1 activity and the cell cycle through Jab1.
Macrophage migration inhibitory factor up-regulates expression of matrix metalloproteinases in synovial fibroblasts of rheumatoid arthritis.
Neuroimmunomodulation by macrophage migration inhibitory factor (MIF).
Regulation of the immune response by macrophage migration inhibitory factor: biological and structural features.
Disulfide analysis reveals a role for macrophage migration inhibitory factor (MIF) as thiol-protein oxidoreductase.
A new group of conserved coactivators that increase the specificity of AP-1 transcription factors.
The immunoregulatory mediator macrophage migration inhibitory factor (MIF) catalyzes a tautomerization reaction.
MIF as a glucocorticoid-induced modulator of cytokine production.
Cloning and characterization of the gene for mouse macrophage migration inhibitory factor (MIF).
MIF is a pituitary-derived cytokine that potentiates lethal endotoxaemia.
Molecular cloning of a cDNA encoding a human macrophage migration inhibitory factor.
Kleemann R, Hausser A, Geiger G, Mischke R, Burger-Kentischer A, Flieger O, Johannes FJ, Roger T, Calandra T, Kapurniotu A, Grell M, Finkelmeier D, Brunner H, Bernhagen J
Nature 2000 Nov 9;408(6809):211-6
Nature 2000 Nov 9;408(6809):211-6
Macrophage migration inhibitory factor up-regulates expression of matrix metalloproteinases in synovial fibroblasts of rheumatoid arthritis.
Onodera S, Kaneda K, Mizue Y, Koyama Y, Fujinaga M, Nishihira J
The Journal of biological chemistry 2000 Jan 7;275(1):444-50
The Journal of biological chemistry 2000 Jan 7;275(1):444-50
Neuroimmunomodulation by macrophage migration inhibitory factor (MIF).
Bucala R
Annals of the New York Academy of Sciences 1998 May 1;840:74-82
Annals of the New York Academy of Sciences 1998 May 1;840:74-82
Regulation of the immune response by macrophage migration inhibitory factor: biological and structural features.
Bernhagen J, Calandra T, Bucala R
Journal of molecular medicine (Berlin, Germany) 1998 Mar;76(3-4):151-61
Journal of molecular medicine (Berlin, Germany) 1998 Mar;76(3-4):151-61
Disulfide analysis reveals a role for macrophage migration inhibitory factor (MIF) as thiol-protein oxidoreductase.
Kleemann R, Kapurniotu A, Frank RW, Gessner A, Mischke R, Flieger O, Jüttner S, Brunner H, Bernhagen J
Journal of molecular biology 1998 Jul 3;280(1):85-102
Journal of molecular biology 1998 Jul 3;280(1):85-102
A new group of conserved coactivators that increase the specificity of AP-1 transcription factors.
Claret FX, Hibi M, Dhut S, Toda T, Karin M
Nature 1996 Oct 3;383(6599):453-7
Nature 1996 Oct 3;383(6599):453-7
The immunoregulatory mediator macrophage migration inhibitory factor (MIF) catalyzes a tautomerization reaction.
Rosengren E, Bucala R, Aman P, Jacobsson L, Odh G, Metz CN, Rorsman H
Molecular medicine (Cambridge, Mass.) 1996 Jan;2(1):143-9
Molecular medicine (Cambridge, Mass.) 1996 Jan;2(1):143-9
MIF as a glucocorticoid-induced modulator of cytokine production.
Calandra T, Bernhagen J, Metz CN, Spiegel LA, Bacher M, Donnelly T, Cerami A, Bucala R
Nature 1995 Sep 7;377(6544):68-71
Nature 1995 Sep 7;377(6544):68-71
Cloning and characterization of the gene for mouse macrophage migration inhibitory factor (MIF).
Mitchell R, Bacher M, Bernhagen J, Pushkarskaya T, Seldin MF, Bucala R
Journal of immunology (Baltimore, Md. : 1950) 1995 Apr 15;154(8):3863-70
Journal of immunology (Baltimore, Md. : 1950) 1995 Apr 15;154(8):3863-70
MIF is a pituitary-derived cytokine that potentiates lethal endotoxaemia.
Bernhagen J, Calandra T, Mitchell RA, Martin SB, Tracey KJ, Voelter W, Manogue KR, Cerami A, Bucala R
Nature 1993 Oct 21;365(6448):756-9
Nature 1993 Oct 21;365(6448):756-9
Molecular cloning of a cDNA encoding a human macrophage migration inhibitory factor.
Weiser WY, Temple PA, Witek-Giannotti JS, Remold HG, Clark SC, David JR
Proceedings of the National Academy of Sciences of the United States of America 1989 Oct;86(19):7522-6
Proceedings of the National Academy of Sciences of the United States of America 1989 Oct;86(19):7522-6
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