RA0487

antibody from Oursmab
Targeting: MIF GIF, GLIF
Provider product page for RA0487

Antibody data

Product number
RA0487 - Provider product page
Provider
Oursmab
Product name
Imalumab (Biosimilar Reference Antibody) (MIF)
Antibody type
Monoclonal
Description
Imalumab (development code BAX-069) is an investigational, fully human monoclonal antibody developed for the treatment of solid tumors and inflammatory conditions. It functions as a targeted inhibitor of Oxidized Macrophage Migration Inhibitory Factor (oxMIF). By binding with high affinity to a specific oxidized isoform of the MIF cytokine, imalumab selectively neutralizes its pathogenic activity. This blockade prevents oxMIF from interacting with its receptors, CD74 and CXCR2/4, thereby inhibiting the downstream pro-inflammatory and pro-tumorigenic signaling pathways that promote cancer cell survival, proliferation, angiogenesis, and immune evasion, as well as chronic inflammation.
Reactivity
Human
Isotype
IgG
Vial size
100 ¦Ìg,1 mg,5 mg-500,10 mg,25 mg,50 mg,214 mg
Concentration
Bottled at the concentration indicated on the vial.
Storage
Store at -20¡ãC or -84¡ãC. Avoid repeated freeze.
MIF protein structure - RA0487 shown in red.