HPA023088

antibody from Atlas Antibodies

Targeting: SLIT2 SLIL3, Slit-2

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

HPA023088

Provider

Atlas Antibodies

Proper citation

Atlas Antibodies Cat#HPA023088, RRID:AB_1857227

Product name

Anti-SLIT2

Antibody type

Polyclonal

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Antigen sequence

LYINSELQDFQKVPMQTGILPGCEPCHKKVCAHGT
CQPSSQAGFTCECQEGWMGPLCDQRTNDPCLGNKC
VHGTCLPINAFSYSCKCLE


Isotype

IgG

Vial size

100 µl

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C.

References

Submitted references

Loss of Expression and Promoter Methylation of SLIT2 Are Associated with Sessile Serrated Adenoma Formation

Beggs A, Jones A, Shepherd N, Arnaout A, Finlayson C, Abulafi A, Morton D, Matthews G, Hodgson S, Tomlinson I, Horwitz M
PLoS Genetics 2013 May;9(5)

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Angiocrine factors modulate tumor proliferation and motility through EphA2 repression of Slit2 tumor suppressor function in endothelium.

Brantley-Sieders DM, Dunaway CM, Rao M, Short S, Hwang Y, Gao Y, Li D, Jiang A, Shyr Y, Wu JY, Chen J
Cancer research 2011 Feb 1;71(3):976-87

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The neuronal repellent SLIT2 is a target for repression by EZH2 in prostate cancer.

Yu J, Cao Q, Yu J, Wu L, Dallol A, Li J, Chen G, Grasso C, Cao X, Lonigro RJ, Varambally S, Mehra R, Palanisamy N, Wu JY, Latif F, Chinnaiyan AM
Oncogene 2010 Sep 30;29(39):5370-80

Immunohistochemistry

Supportive validation

Submitted by

Atlas Antibodies (provider)

Main image

Experimental details

Immunohistochemical staining of human stomach shows strong cytoplasmic and membranous positivity in glandular cells.

Sample type

HUMAN