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ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [3]
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- Validations
- Immunohistochemistry [1]
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- Product number
- NBP1-80742 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NBP1-80742, RRID:AB_11015076
- Product name
- Rabbit Polyclonal Slit2 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. Specificity of human Slit2 antibody verified on a Protein Array containing target protein plus 383 other non-specific proteins.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references Loss of expression and promoter methylation of SLIT2 are associated with sessile serrated adenoma formation.
Angiocrine factors modulate tumor proliferation and motility through EphA2 repression of Slit2 tumor suppressor function in endothelium.
The neuronal repellent SLIT2 is a target for repression by EZH2 in prostate cancer.
Beggs AD, Jones A, Shepherd N, Arnaout A, Finlayson C, Abulafi AM, Morton DG, Matthews GM, Hodgson SV, Tomlinson IP
PLoS genetics 2013 May;9(5):e1003488
PLoS genetics 2013 May;9(5):e1003488
Angiocrine factors modulate tumor proliferation and motility through EphA2 repression of Slit2 tumor suppressor function in endothelium.
Brantley-Sieders DM, Dunaway CM, Rao M, Short S, Hwang Y, Gao Y, Li D, Jiang A, Shyr Y, Wu JY, Chen J
Cancer research 2011 Feb 1;71(3):976-87
Cancer research 2011 Feb 1;71(3):976-87
The neuronal repellent SLIT2 is a target for repression by EZH2 in prostate cancer.
Yu J, Cao Q, Yu J, Wu L, Dallol A, Li J, Chen G, Grasso C, Cao X, Lonigro RJ, Varambally S, Mehra R, Palanisamy N, Wu JY, Latif F, Chinnaiyan AM
Oncogene 2010 Sep 30;29(39):5370-80
Oncogene 2010 Sep 30;29(39):5370-80
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Supportive validation
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- Novus Biologicals (provider)
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- Experimental details
- Immunohistochemistry-Paraffin: Slit2 Antibody [NBP1-80742] - Staining of human stomach shows strong cytoplasmic and membranous positivity in glandular cells.
