Explore
Validate
Learn
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [92]
- Comments [0]
- Validations
- Western blot [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 22089-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#22089-1-AP, RRID:AB_11182176
- Product name
- androgen receptor antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated androgen receptor antibody (Cat. #22089-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references DGAT1 mediates sex-specific CD8(+) T cell antitumour responses.
Cholecystokinin (CCK) mediates CCKBR to regulate androgen secretion via the steroid pathway in Bactrian camel Sertoli cells.
ZDHHC2-Dependent Palmitoylation Dictates Ferroptosis and Castration Sensitivity in Prostate Cancer via Controlling ACSL4 Degradation and Lipid Peroxidation.
Inhibition of the RORC/GPX4 mediated ferroptosis regulatory axis suppresses tumor growth and alleviates enzalutamide resistance in prostate cancer.
Targeting Hsp70 triggers ferroptosis: a novel anti-cancer mechanism of a marine natural product in prostate cancer.
Discovery of SKP2-Recruiting PROTACs for Target Protein Degradation.
Androgen receptor inhibitor ameliorates pulmonary arterial hypertension by enhancing the apoptosis level through suppressing the Notch3/Hes5 pathway.
The role and mechanism of quercetin in improving late-onset hypogonadism through network analysis and experimental validation.
circEFR3A promotes breast cancer progression by sponging miR-590-3p to upregulate androgen receptor expression.
Reduced mesencephalic astrocyte-derived neurotrophic factor expression by mutant androgen receptor contributes to neurodegeneration in a model of spinal and bulbar muscular atrophy pathology.
HOMER3 orchestrates SRC-YAP1 activity that promotes tumor cell growth and antagonizes anti-tumor immunotherapy in prostate cancer.
Nuclear receptor coactivator 4 linked to follicular dysplasia in polycystic ovary syndrome: A key regulator that aggravates ovarian granulosa cells ferritinophagy and ferroptosis.
Exercise improves glucose and lipid metabolism in high fat diet feeding male mice through androgen/androgen receptor-mediated metabolism regulatory factors.
Overactivation of PERK-Mediated Endoplasmic Reticulum Stress-Induced Testis Damage in Chronically Stressed Mice.
Conserved signals control self-organization and symmetry breaking of murine bilayered epithelia during development and regeneration.
BAP18, as a corepressor of AR together with the SIN3A/HDAC complex, promotes AR-positive triple-negative breast cancer progression.
Hsa_circ_0038737 promotes PARPi resistance in castration-resistant prostate cancer via IGF2BP3-mediated DNPH1 mRNA stabilization.
Jiawei Danxuan Koukang and its key component Quercetin intervened in OSF carcinogenesis by inhibiting the AR/eIF5A2 signaling pathway-mediated EMT.
The effects of 17β-trenbolone and bisphenol A on sexual behavior and social dominance via the hypothalamic-pituitary-gonadal axis in male mice.
RBAP48 facilitates the oral squamous cell carcinoma process in an androgen receptor-dependent and independent manners.
Liquiritigenin protects against cadmium-induced testis damage in mice by inhibiting apoptosis and activating androgen receptor.
17β-Trenbolone Exposure Enhances Muscle Activity and Exacerbates Parkinson's Disease Progression in Male Mice.
DLGAP5 upregulates E2F1 to promote prostate adenocarcinoma neuroendocrine differentiation.
A pH/MMP-9 smart dual-responsive liposome GBE@LP co-delivers and controls the release of GB1107/BMS1166/Enzalutamide for liver cancer immunotherapy.
Perioperative Testosterone Supplementation Improves Short-Term Outcomes of Anterior Urethroplasty in Hypogonadal Models: Insights From a Preclinical Rabbit Study.
Melatonin receptor 1a alleviates sleep fragmentation-aggravated testicular injury in T2DM by suppression of TAB1/TAK1 complex through FGFR1.
Upregulated let-7 expression in the follicular fluid of patients with endometriomas leads to dysfunction of granulosa cells through targeting of IGF1R.
The mechanism study of targeting DPP4 in regulating ferroptosis and its influence on endometrial receptivity in PCOS.
A Super-Enhancer-Driven Transcriptional Regulatory Circuit Underlying Abiraterone Resistance in Castration-Resistant Prostate Cancer.
Elevated serum levels of GPX4, NDUFS4, PRDX5, and TXNRD2 as predictive biomarkers for castration resistance in prostate cancer patients: an exploratory study.
Cannabidiol Enhances the Anticancer Activity of Etoposide on Prostate Cancer Cells.
The FTO Mediated N6-Methyladenosine Modification of DDIT4 Regulation with Tumorigenesis and Metastasis in Prostate Cancer.
Darolutamide-mediated phospholipid remodeling induces ferroptosis through the SREBP1-FASN axis in prostate cancer.
Diesel exhaust particle inhalation in conjunction with high-fat diet consumption alters the expression of pulmonary SARS-COV-2 infection pathways, which is mitigated by probiotic treatment in C57BL/6 male mice.
Polystyrene microplastics trigger testosterone decline via GPX1.
Thyroxine regulates pig Sertoli cell line proliferation and maturation through the IKK/NFκB and p38 MAPK signaling pathways.
Comprehensive analysis and validation of TP73 as a biomarker for calcium oxalate nephrolithiasis using machine learning and in vivo and in vitro experiments.
The effect of gonadotropin-inhibitory hormone on steroidogenesis and spermatogenesis by acting through the hypothalamic-pituitary-testis axis in mice.
Androgens exacerbate hepatic triglyceride accumulation in rats with polycystic ovary syndrome by downregulating MTTP expression.
Retinoblastoma-associated protein is important for TRIM24-mediated activation of the mTOR signaling pathway through DUSP2 action in prostate cancer.
GL-V9 inhibits the activation of AR-AKT-HK2 signaling networks and induces prostate cancer cell apoptosis through mitochondria-mediated mechanism.
CAPN2 promotes apalutamide resistance in metastatic hormone-sensitive prostate cancer by activating protective autophagy.
Chemerin regulates glucose and lipid metabolism by changing mitochondrial structure and function associated with androgen/androgen receptor.
Anticancer Effect of Theranekron(®) on Androgen-Dependent Prostate Cancer Cells.
Exosome-delivered NR2F1-AS1 and NR2F1 drive phenotypic transition from dormancy to proliferation in treatment-resistant prostate cancer via stabilizing hormonal receptors.
MitoQ enhances CYP19A1 expression to stimulate WNT/β-catenin signaling pathway for promoting hair growth in androgenetic alopecia.
Chemerin affects blood lipid profile of high-fat diet male mice in sedentary and exercise states via glucose and lipid metabolism enzymes.
M6A-modified circRBM33 promotes prostate cancer progression via PDHA1-mediated mitochondrial respiration regulation and presents a potential target for ARSI therapy.
Four novel mutations identification in 17 beta-hydroxysteroid dehydrogenase-3 deficiency and our clinical experience: possible benefits of early treatment.
Estrogens drive the endoplasmic reticulum-associated degradation and promote proto-oncogene c-Myc expression in prostate cancer cells by androgen receptor/estrogen receptor signaling.
Triiodothyronine positively regulates endoplasmic reticulum-associated degradation (ERAD) and promotes androgenic signaling in androgen-dependent prostate cancer cells.
Effect of Tamoxifen on Proteome Expression during In Vitro Myogenesis in Murine Skeletal Muscle C(2)C(12) Cells.
WTAP boosts lipid oxidation and induces diabetic cardiac fibrosis by enhancing AR methylation.
A new tissue-agnostic microfluidic device to model physiology and disease: the lattice platform.
1,25(OH)(2) D(3) induced vitamin D receptor signaling negatively regulates endoplasmic reticulum-associated degradation (ERAD) and androgen receptor signaling in human prostate cancer cells.
Two-in-One Polymeric NO-Donor Prodrugs Mediate Precision and Synergistic Prostate Cancer Treatment.
Lysine butyrylation of HSP90 regulated by KAT8 and HDAC11 confers chemoresistance.
Progesterone regulates the endoplasmic reticulum-associated degradation and Unfolded Protein Response axis by mimicking the androgenic stimulation in prostate cancer cells.
Therapeutic targeting of histone lysine demethylase KDM4B blocks the growth of castration-resistant prostate cancer.
Region-resolved multi-omics of the mouse eye.
RNA N6-methyladenosine-modified-binding protein YTHDF1 promotes prostate cancer progression by regulating androgen function-related gene TRIM68.
In silico, in vitro and in vivo studies: Dibutyl phthalate promotes prostate cancer cell proliferation by activating Forkhead Box M1 and remission after Natura-α pretreatment.
SMAD3 promotes expression and activity of the androgen receptor in prostate cancer.
Quercetin in Tonglong Qibi decoction ameliorates testosterone-induced benign prostatic hyperplasia in rats by regulating Nrf2 signalling pathways and oxidative stress.
Syce1 and Syce3 regulate testosterone and dihydrotestosterone synthesis via steroidogenic pathways in mouse Sertoli and Leydig cells.
Targeting APLN/APJ restores blood-testis barrier and improves spermatogenesis in murine and human diabetic models.
Betaine attenuate chronic restraint stress-induced changes in testicular damage and oxidative stress in male mice.
Effects of testosterone on skin structure and factors related to androgen conversion and binding in Hetian sheep.
N-glycosylation of GDF15 abolishes its inhibitory effect on EGFR in AR inhibitor-resistant prostate cancer cells.
Identification of endocrine-disrupting chemicals targeting the genes and pathways of genital anomalies in males.
Studying the nature of ascending-descending-floating-sinking of Chinese medicines based on gonadotropin-releasing hormone.
α-Terthienyl induces prostate cancer cell death through inhibiting androgen receptor expression.
Cypermethrin inhibits proliferation of Sertoli cells through AR involving DAB2IP/PI3K/AKT signaling pathway in vitro.
RNF8 up-regulates AR/ARV7 action to contribute to advanced prostate cancer progression.
PRPF6 promotes androgen receptor/androgen receptor-variant 7 actions in castration-resistant prostate cancer cells.
Icariin Ameliorates Diabetic Renal Tubulointerstitial Fibrosis by Restoring Autophagy via Regulation of the miR-192-5p/GLP-1R Pathway.
Expression of hormone receptors predicts survival and platinum sensitivity of high-grade serous ovarian cancer.
The function of BAP18 on modulation of androgen receptor action in luteinized granulosa cells from normal weight women with and without PCOS.
Androgen Receptor Stimulates Hexokinase 2 and Induces Glycolysis by PKA/CREB Signaling in Hepatocellular Carcinoma.
Identification of low-frequency variants of UGT1A3 associated with bladder cancer risk by next-generation sequencing.
Pyruvate-Enriched Oral Rehydration Solution Improves Glucometabolic Disorders in the Kidneys of Diabetic db/db Mice.
The Expression and Prognostic Significance of Claudin-8 and Androgen Receptor in Breast Cancer.
Splicing factor PRPF6 upregulates oncogenic androgen receptor signaling pathway in hepatocellular carcinoma.
Co-transplantation with adipose-derived cells to improve parathyroid transplantation in a mice model.
Androgen aggravates liver fibrosis by activation of NLRP3 inflammasome in CCl(4)-induced liver injury mouse model.
RNF6 promotes myeloma cell proliferation and survival by inducing glucocorticoid receptor polyubiquitination.
Imidacloprid disrupts the endocrine system by interacting with androgen receptor in male mice.
Melatonin protects the mouse testis against heat-induced damage.
ETA-mediated anti-TNF-α therapy ameliorates the phenotype of PCOS model induced by letrozole.
The preoperative neutrophil-to-lymphocyte ratio is not a marker of prostate cancer characteristics but is an independent predictor of biochemical recurrence in patients receiving radical prostatectomy.
miR-323-3p regulates the steroidogenesis and cell apoptosis in polycystic ovary syndrome (PCOS) by targeting IGF-1.
Testosterone regulates 3T3-L1 pre-adipocyte differentiation and epididymal fat accumulation in mice through modulating macrophage polarization.
Madi A, Shi H, Su M, Mady A, Lv B, Wang H, Yang B, Yan Z, Jin X, Wu L, Lv M, Hering M, Ma S, Mieg A, Zettl F, Yan X, Mohr K, Knabe N, Poschet G, Richter K, Schleußner N, Jackstadt RF, Loges S, Papavasiliou FN, Wang X, Wu J, Cui G
Nature metabolism 2026 Mar;8(3):685-703
Nature metabolism 2026 Mar;8(3):685-703
Cholecystokinin (CCK) mediates CCKBR to regulate androgen secretion via the steroid pathway in Bactrian camel Sertoli cells.
Wang Q, Wang W, Nan J, Zhang Y, Zhao X
The Journal of steroid biochemistry and molecular biology 2026 Mar;257:106922
The Journal of steroid biochemistry and molecular biology 2026 Mar;257:106922
ZDHHC2-Dependent Palmitoylation Dictates Ferroptosis and Castration Sensitivity in Prostate Cancer via Controlling ACSL4 Degradation and Lipid Peroxidation.
Shao S, Li W, Hong Y, Zeng R, Zhu L, Yi L, Li Y, Wang Y, Huang H, Jiang X, Jin X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(1):e14077
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(1):e14077
Inhibition of the RORC/GPX4 mediated ferroptosis regulatory axis suppresses tumor growth and alleviates enzalutamide resistance in prostate cancer.
Li Y, Zhang B, Zhang Z, Yan W, Wang H, Xu X, Lv A, Liao Z, Guo L
Cellular & molecular biology letters 2026 Jan 24;31(1):11
Cellular & molecular biology letters 2026 Jan 24;31(1):11
Targeting Hsp70 triggers ferroptosis: a novel anti-cancer mechanism of a marine natural product in prostate cancer.
Liu Q, Cong M, Gao C, Liu Y, Wang J, Wang X
Natural products and bioprospecting 2026 Feb 5;16(1):34
Natural products and bioprospecting 2026 Feb 5;16(1):34
Discovery of SKP2-Recruiting PROTACs for Target Protein Degradation.
Dong G, Huang A, Zhao Z, Lai B, Pan X, Yang H, Xu X, Wang T, Zhao F, Zhang Z, Xue Y, Deng G, Deng W, Chen J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(20):e15159
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(20):e15159
Androgen receptor inhibitor ameliorates pulmonary arterial hypertension by enhancing the apoptosis level through suppressing the Notch3/Hes5 pathway.
Sun J, Lin J, Yin D, Pan Z, Ye Y, Wang Y, Wang X, Guo Q
Frontiers in pharmacology 2025;16:1572489
Frontiers in pharmacology 2025;16:1572489
The role and mechanism of quercetin in improving late-onset hypogonadism through network analysis and experimental validation.
Wu X, Zhao H, Huang X, Lu P, Zhang R, Guan Q, Yu C
Naunyn-Schmiedeberg's archives of pharmacology 2025 Sep;398(9):12031-12046
Naunyn-Schmiedeberg's archives of pharmacology 2025 Sep;398(9):12031-12046
circEFR3A promotes breast cancer progression by sponging miR-590-3p to upregulate androgen receptor expression.
Mi Y, Wang X, Song H, Wu Z, Li S, Liu F, Liu W, Sang M, Geng C
Oncology letters 2025 Sep;30(3):446
Oncology letters 2025 Sep;30(3):446
Reduced mesencephalic astrocyte-derived neurotrophic factor expression by mutant androgen receptor contributes to neurodegeneration in a model of spinal and bulbar muscular atrophy pathology.
Qin Y, Zhu W, Guo T, Zhang Y, Xing T, Yin P, Li S, Li XJ, Yang S
Neural regeneration research 2025 Sep 1;20(9):2655-2666
Neural regeneration research 2025 Sep 1;20(9):2655-2666
HOMER3 orchestrates SRC-YAP1 activity that promotes tumor cell growth and antagonizes anti-tumor immunotherapy in prostate cancer.
Tong T, Lei H, Huang M, Yang Z, Dai X, Zou H, Guo Y, Luo J, Teng Q, Cao F, Pang J, Li P
Oncogene 2025 Oct;44(41):3895-3908
Oncogene 2025 Oct;44(41):3895-3908
Nuclear receptor coactivator 4 linked to follicular dysplasia in polycystic ovary syndrome: A key regulator that aggravates ovarian granulosa cells ferritinophagy and ferroptosis.
Chen D, Wang Y, Wang X, Si X, Weng Y, Liu S, Pan W, Xu Y, Wang Y, Zhang Y
Biochimica et biophysica acta. Molecular basis of disease 2025 Oct;1871(7):167955
Biochimica et biophysica acta. Molecular basis of disease 2025 Oct;1871(7):167955
Exercise improves glucose and lipid metabolism in high fat diet feeding male mice through androgen/androgen receptor-mediated metabolism regulatory factors.
Hu J, Yang Y, Fu S, Yu X, Wang X
Biochimica et biophysica acta. Molecular basis of disease 2025 Oct;1871(7):167926
Biochimica et biophysica acta. Molecular basis of disease 2025 Oct;1871(7):167926
Overactivation of PERK-Mediated Endoplasmic Reticulum Stress-Induced Testis Damage in Chronically Stressed Mice.
Peng L, Tang X, Tang P, Zhou C, Xiang Y, Cao W, Li Y, Peng C, Xu Y, Li S
ACS omega 2025 Oct 7;10(39):44937-44947
ACS omega 2025 Oct 7;10(39):44937-44947
Conserved signals control self-organization and symmetry breaking of murine bilayered epithelia during development and regeneration.
Journot RP, Huyghe M, Barthelemy A, Couto-Moreira H, Deshayes T, Harari L, Sumbal J, Faraldo MM, Dubail M, Fouillade C, Fre S
Developmental cell 2025 Oct 6;60(19):2576-2593.e6
Developmental cell 2025 Oct 6;60(19):2576-2593.e6
BAP18, as a corepressor of AR together with the SIN3A/HDAC complex, promotes AR-positive triple-negative breast cancer progression.
Zhang Y, Jin Z, Wu Y, Tang X, Wang C, Wang S, Li Y, Zhang T, Jin F, Lu H, Zhao Y, Zheng A
Cell & bioscience 2025 Oct 29;15(1):147
Cell & bioscience 2025 Oct 29;15(1):147
Hsa_circ_0038737 promotes PARPi resistance in castration-resistant prostate cancer via IGF2BP3-mediated DNPH1 mRNA stabilization.
Wang Z, Ge Q, Anwaier A, Liu S, Tian X, Zhang Z, Feng T, Hong Z, Ye D, Xu W, Qin X
Molecular cancer 2025 Oct 2;24(1):238
Molecular cancer 2025 Oct 2;24(1):238
Jiawei Danxuan Koukang and its key component Quercetin intervened in OSF carcinogenesis by inhibiting the AR/eIF5A2 signaling pathway-mediated EMT.
Dai Y, Wang C, Xiao Y, Tan Y, Ye Y, Liu Y, Zeng Q, Tan J
Archives of oral biology 2025 May;173:106194
Archives of oral biology 2025 May;173:106194
The effects of 17β-trenbolone and bisphenol A on sexual behavior and social dominance via the hypothalamic-pituitary-gonadal axis in male mice.
Zuo X, Sun M, Bai H, Zhang S, Luan J, Yu Q, Fu Z, Zhao Q, Sun M, Zhao X, Feng X
Journal of environmental sciences (China) 2025 May;151:54-67
Journal of environmental sciences (China) 2025 May;151:54-67
RBAP48 facilitates the oral squamous cell carcinoma process in an androgen receptor-dependent and independent manners.
Wang X, Yan G, Li H, Wang C, Kang Y, Wang S, Liu W, Lin L, Zou R, Zeng K, Wang M, Luan R, Zhou B, Bai Y, Yang D, Ning B, Sun G, Zhao Y
Communications biology 2025 May 30;8(1):829
Communications biology 2025 May 30;8(1):829
Liquiritigenin protects against cadmium-induced testis damage in mice by inhibiting apoptosis and activating androgen receptor.
Yuan S, Guo J, Yang B, Huang AX, Hu S, Li Y, Chen J, Yuan B, Yang J
Biochemical and biophysical research communications 2025 May 20;759:151642
Biochemical and biophysical research communications 2025 May 20;759:151642
17β-Trenbolone Exposure Enhances Muscle Activity and Exacerbates Parkinson's Disease Progression in Male Mice.
Zuo X, Bai HJ, Zhao QL, Zhang SH, Zhao X, Feng XZ
Molecular neurobiology 2025 Mar;62(3):3053-3066
Molecular neurobiology 2025 Mar;62(3):3053-3066
DLGAP5 upregulates E2F1 to promote prostate adenocarcinoma neuroendocrine differentiation.
Liang L, Shen Z, Zhang K, Zhang C, Dong L, Shi R, Hua L, Zhao R, Feng N
Life sciences 2025 Mar 15;365:123442
Life sciences 2025 Mar 15;365:123442
A pH/MMP-9 smart dual-responsive liposome GBE@LP co-delivers and controls the release of GB1107/BMS1166/Enzalutamide for liver cancer immunotherapy.
Lu S, Zhang C, Wu H, Wang J, Wang J, Zhao L, Ren T, Li G
Materials today. Bio 2025 Jun;32:101801
Materials today. Bio 2025 Jun;32:101801
Perioperative Testosterone Supplementation Improves Short-Term Outcomes of Anterior Urethroplasty in Hypogonadal Models: Insights From a Preclinical Rabbit Study.
Xue J, Liu Y, Ye H, Feng C, Wu D
Urology 2025 Jul;201:134-143
Urology 2025 Jul;201:134-143
Melatonin receptor 1a alleviates sleep fragmentation-aggravated testicular injury in T2DM by suppression of TAB1/TAK1 complex through FGFR1.
Zhang X, Tang X, Gao T, Guo Y, Lu G, Liu Q, Li J, Wang J, Liu M, Zhang D, Tang Y, Gu J
Acta pharmaceutica Sinica. B 2025 Jul;15(7):3591-3610
Acta pharmaceutica Sinica. B 2025 Jul;15(7):3591-3610
Upregulated let-7 expression in the follicular fluid of patients with endometriomas leads to dysfunction of granulosa cells through targeting of IGF1R.
Shi L, Ying H, Dai Y, Rong Y, Chen J, Zhou F, Wang S, Xu S, Tong X, Zhang S
Human reproduction (Oxford, England) 2025 Jan 1;40(1):119-137
Human reproduction (Oxford, England) 2025 Jan 1;40(1):119-137
The mechanism study of targeting DPP4 in regulating ferroptosis and its influence on endometrial receptivity in PCOS.
Zhang J, Wang R, Tian X, Ding N, He Y, Wang K, Tao C, Cai J, Jian Q, Wang F
Biology of sex differences 2025 Dec 23;16(1):107
Biology of sex differences 2025 Dec 23;16(1):107
A Super-Enhancer-Driven Transcriptional Regulatory Circuit Underlying Abiraterone Resistance in Castration-Resistant Prostate Cancer.
Jiang L, Wang J, Peng G, Zhang H, Fang J, Gao Y, Lou E, Liu Y, Ding W, Liu B, Mao Q, Jiang L, Liu A, Li X, Hu S, Ma Q, Zheng Y, Zhao Z, Shi X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Aug;12(31):e01284
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Aug;12(31):e01284
Elevated serum levels of GPX4, NDUFS4, PRDX5, and TXNRD2 as predictive biomarkers for castration resistance in prostate cancer patients: an exploratory study.
Wang R, Wang S, Mi Y, Huang T, Wang J, Ni J, Wang J, Yin J, Li M, Ran X, Fan S, Sun Q, Tan SY, Phillip Koeffler H, Ding L, Chen YQ, Feng N
British journal of cancer 2025 Apr;132(6):543-557
British journal of cancer 2025 Apr;132(6):543-557
Cannabidiol Enhances the Anticancer Activity of Etoposide on Prostate Cancer Cells.
Erzurumlu Y, Catakli D
Cannabis and cannabinoid research 2025 Apr;10(2):258-276
Cannabis and cannabinoid research 2025 Apr;10(2):258-276
The FTO Mediated N6-Methyladenosine Modification of DDIT4 Regulation with Tumorigenesis and Metastasis in Prostate Cancer.
Zhao Y, Hu X, Yu H, Sun H, Zhang L, Shao C
Research (Washington, D.C.) 2024;7:0313
Research (Washington, D.C.) 2024;7:0313
Darolutamide-mediated phospholipid remodeling induces ferroptosis through the SREBP1-FASN axis in prostate cancer.
Li B, Cheng B, Huang H, Huang S, Yu S, Li Z, Peng S, Du T, Xie R, Huang H
International journal of biological sciences 2024;20(12):4635-4653
International journal of biological sciences 2024;20(12):4635-4653
Diesel exhaust particle inhalation in conjunction with high-fat diet consumption alters the expression of pulmonary SARS-COV-2 infection pathways, which is mitigated by probiotic treatment in C57BL/6 male mice.
Nguyen-Alley K, Daniel S, Phillippi DT, Armstrong TD, Johnson B, Ihemeremadu W, Lund AK
Particle and fibre toxicology 2024 Sep 29;21(1):40
Particle and fibre toxicology 2024 Sep 29;21(1):40
Polystyrene microplastics trigger testosterone decline via GPX1.
Qu J, Wu L, Mou L, Liu C
The Science of the total environment 2024 Oct 15;947:174536
The Science of the total environment 2024 Oct 15;947:174536
Thyroxine regulates pig Sertoli cell line proliferation and maturation through the IKK/NFκB and p38 MAPK signaling pathways.
Li J, Zhang SX, Wang DL, Qi JJ, Bai CY, Sun H, Sun BX, Liang S
Theriogenology 2024 Oct 1;227:1-8
Theriogenology 2024 Oct 1;227:1-8
Comprehensive analysis and validation of TP73 as a biomarker for calcium oxalate nephrolithiasis using machine learning and in vivo and in vitro experiments.
Zhou Z, Wang L, Cai L, Gao P, Lu H, Wu Z
Urolithiasis 2024 Nov 16;52(1):164
Urolithiasis 2024 Nov 16;52(1):164
The effect of gonadotropin-inhibitory hormone on steroidogenesis and spermatogenesis by acting through the hypothalamic-pituitary-testis axis in mice.
Dai T, Yang L, Wei S, Chu Y, Dan X
Endocrine 2024 May;84(2):745-756
Endocrine 2024 May;84(2):745-756
Androgens exacerbate hepatic triglyceride accumulation in rats with polycystic ovary syndrome by downregulating MTTP expression.
Wang D, Zhao H, Xing C, Lv B, Wang X, He B
Endocrine 2024 May;84(2):735-744
Endocrine 2024 May;84(2):735-744
Retinoblastoma-associated protein is important for TRIM24-mediated activation of the mTOR signaling pathway through DUSP2 action in prostate cancer.
Ren D, Li W, Zeng R, Liu X, Liang H, Xiong W, Yang C, Jin X
Cell death and differentiation 2024 May;31(5):592-604
Cell death and differentiation 2024 May;31(5):592-604
GL-V9 inhibits the activation of AR-AKT-HK2 signaling networks and induces prostate cancer cell apoptosis through mitochondria-mediated mechanism.
Wang R, Min Q, Guo Y, Zhou Y, Zhang X, Wang D, Gao Y, Wei L
iScience 2024 Mar 15;27(3):109246
iScience 2024 Mar 15;27(3):109246
CAPN2 promotes apalutamide resistance in metastatic hormone-sensitive prostate cancer by activating protective autophagy.
Qi Z, Bai X, Wu L, Zhang P, Guo Z, Yu Y
Journal of translational medicine 2024 Jun 6;22(1):538
Journal of translational medicine 2024 Jun 6;22(1):538
Chemerin regulates glucose and lipid metabolism by changing mitochondrial structure and function associated with androgen/androgen receptor.
Yin L, Tang H, Qu J, Jia Y, Zhang Q, Wang X
American journal of physiology. Endocrinology and metabolism 2024 Jun 1;326(6):E869-E887
American journal of physiology. Endocrinology and metabolism 2024 Jun 1;326(6):E869-E887
Anticancer Effect of Theranekron(®) on Androgen-Dependent Prostate Cancer Cells.
Erzurumlu Y, Doğan HK, Çataklı D
Turkish journal of pharmaceutical sciences 2024 Jan 19;20(6):368-373
Turkish journal of pharmaceutical sciences 2024 Jan 19;20(6):368-373
Exosome-delivered NR2F1-AS1 and NR2F1 drive phenotypic transition from dormancy to proliferation in treatment-resistant prostate cancer via stabilizing hormonal receptors.
Chen W, Mao Y, Zhan Y, Li W, Wu J, Mao X, Xu B, Shu F
Journal of nanobiotechnology 2024 Dec 18;22(1):761
Journal of nanobiotechnology 2024 Dec 18;22(1):761
MitoQ enhances CYP19A1 expression to stimulate WNT/β-catenin signaling pathway for promoting hair growth in androgenetic alopecia.
Li Y, Dong T, Yang F, Jin S, Xiong R, Song X, Guan C
European journal of pharmacology 2024 Dec 15;985:177094
European journal of pharmacology 2024 Dec 15;985:177094
Chemerin affects blood lipid profile of high-fat diet male mice in sedentary and exercise states via glucose and lipid metabolism enzymes.
Jia Y, Yang Y, Qu J, Yin L, Wang X
Endocrine connections 2024 Apr 1;13(4)
Endocrine connections 2024 Apr 1;13(4)
M6A-modified circRBM33 promotes prostate cancer progression via PDHA1-mediated mitochondrial respiration regulation and presents a potential target for ARSI therapy.
Zhong C, Long Z, Yang T, Wang S, Zhong W, Hu F, Teoh JY, Lu J, Mao X
International journal of biological sciences 2023;19(5):1543-1563
International journal of biological sciences 2023;19(5):1543-1563
Four novel mutations identification in 17 beta-hydroxysteroid dehydrogenase-3 deficiency and our clinical experience: possible benefits of early treatment.
Wang Y, Xu Y, Zhang H, Yin D, Pan Y, He X, Li S, Cheng Z, Zhu G, Zhao T, Huang H, Zhu M
Frontiers in endocrinology 2023;14:1267967
Frontiers in endocrinology 2023;14:1267967
Estrogens drive the endoplasmic reticulum-associated degradation and promote proto-oncogene c-Myc expression in prostate cancer cells by androgen receptor/estrogen receptor signaling.
Erzurumlu Y, Dogan HK, Catakli D, Aydogdu E, Muhammed MT
Journal of cell communication and signaling 2023 Sep;17(3):793-811
Journal of cell communication and signaling 2023 Sep;17(3):793-811
Triiodothyronine positively regulates endoplasmic reticulum-associated degradation (ERAD) and promotes androgenic signaling in androgen-dependent prostate cancer cells.
Erzurumlu Y, Muhammed MT
Cellular signalling 2023 Sep;109:110745
Cellular signalling 2023 Sep;109:110745
Effect of Tamoxifen on Proteome Expression during In Vitro Myogenesis in Murine Skeletal Muscle C(2)C(12) Cells.
Morris EA, Abreu A, Scordilis SP
Journal of proteome research 2023 Sep 1;22(9):3040-3053
Journal of proteome research 2023 Sep 1;22(9):3040-3053
WTAP boosts lipid oxidation and induces diabetic cardiac fibrosis by enhancing AR methylation.
Song K, Sun H, Tu B, Zhou Y, Lin LC, Liu ZY, Li R, Yang JJ, Zhang Y, Zhao JY, Tao H
iScience 2023 Oct 20;26(10):107931
iScience 2023 Oct 20;26(10):107931
A new tissue-agnostic microfluidic device to model physiology and disease: the lattice platform.
Campo H, Zha D, Pattarawat P, Colina J, Zhang D, Murphy A, Yoon J, Russo A, Rogers HB, Lee HC, Zhang J, Trotter K, Wagner S, Ingram A, Pavone ME, Dunne SF, Boots CE, Urbanek M, Xiao S, Burdette JE, Woodruff TK, Kim JJ
Lab on a chip 2023 Nov 7;23(22):4821-4833
Lab on a chip 2023 Nov 7;23(22):4821-4833
1,25(OH)(2) D(3) induced vitamin D receptor signaling negatively regulates endoplasmic reticulum-associated degradation (ERAD) and androgen receptor signaling in human prostate cancer cells.
Erzurumlu Y, Aydogdu E, Dogan HK, Catakli D, Muhammed MT, Buyuksandic B
Cellular signalling 2023 Mar;103:110577
Cellular signalling 2023 Mar;103:110577
Two-in-One Polymeric NO-Donor Prodrugs Mediate Precision and Synergistic Prostate Cancer Treatment.
Zhao B, Wan Y, Zhou X, Zhang J, Chen J, Yang J, Liu Y, Chen W, Zhong Y, Qian H
ACS applied materials & interfaces 2023 Jul 19;15(28):33309-33321
ACS applied materials & interfaces 2023 Jul 19;15(28):33309-33321
Lysine butyrylation of HSP90 regulated by KAT8 and HDAC11 confers chemoresistance.
He Y, Zheng CC, Yang J, Li SJ, Xu TY, Wei X, Chen WY, Jiang ZL, Xu JJ, Zhang GG, Cheng C, Chen KS, Shi XY, Qin DJ, Liu JB, Li B
Cell discovery 2023 Jul 18;9(1):74
Cell discovery 2023 Jul 18;9(1):74
Progesterone regulates the endoplasmic reticulum-associated degradation and Unfolded Protein Response axis by mimicking the androgenic stimulation in prostate cancer cells.
Erzurumlu Y, Dogan HK, Catakli D
Molecular biology reports 2023 Feb;50(2):1253-1265
Molecular biology reports 2023 Feb;50(2):1253-1265
Therapeutic targeting of histone lysine demethylase KDM4B blocks the growth of castration-resistant prostate cancer.
Duan L, Chen YA, Liang Y, Chen Z, Lu J, Fang Y, Cao J, Lu J, Zhao H, Pong RC, Hernandez E, Kapur P, Tran TAT, Smith T, Martinez ED, Ahn JM, Hsieh JT, Luo JH, Liu ZP
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Feb;158:114077
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Feb;158:114077
Region-resolved multi-omics of the mouse eye.
Xiang H, Zhang B, Wang Y, Xu N, Zhang F, Luo R, Ji M, Ding C
Cell reports 2023 Feb 28;42(2):112121
Cell reports 2023 Feb 28;42(2):112121
RNA N6-methyladenosine-modified-binding protein YTHDF1 promotes prostate cancer progression by regulating androgen function-related gene TRIM68.
Nie Q, Wu X, Huang Y, Guo T, Kuang J, Du C
European journal of medical research 2023 Dec 2;28(1):552
European journal of medical research 2023 Dec 2;28(1):552
In silico, in vitro and in vivo studies: Dibutyl phthalate promotes prostate cancer cell proliferation by activating Forkhead Box M1 and remission after Natura-α pretreatment.
Bu H, Tang S, Liu G, Miao C, Zhou X, Yang H, Liu B
Toxicology 2023 Apr;488:153465
Toxicology 2023 Apr;488:153465
SMAD3 promotes expression and activity of the androgen receptor in prostate cancer.
Jeon HY, Pornour M, Ryu H, Khadka S, Xu R, Jang J, Li D, Chen H, Hussain A, Fazli L, Gleave M, Dong X, Huang F, Wang Q, Barbieri C, Qi J
Nucleic acids research 2023 Apr 11;51(6):2655-2670
Nucleic acids research 2023 Apr 11;51(6):2655-2670
Quercetin in Tonglong Qibi decoction ameliorates testosterone-induced benign prostatic hyperplasia in rats by regulating Nrf2 signalling pathways and oxidative stress.
Fu W, Chen S, Zhang Z, Chen Y, You X, Li Q
Andrologia 2022 Oct;54(9):e14502
Andrologia 2022 Oct;54(9):e14502
Syce1 and Syce3 regulate testosterone and dihydrotestosterone synthesis via steroidogenic pathways in mouse Sertoli and Leydig cells.
Wang Q, Yan Q, Nan J, Wang J, Zhang Y, Zhao X
The Journal of steroid biochemistry and molecular biology 2022 Oct;223:106135
The Journal of steroid biochemistry and molecular biology 2022 Oct;223:106135
Targeting APLN/APJ restores blood-testis barrier and improves spermatogenesis in murine and human diabetic models.
Song K, Yang X, An G, Xia X, Zhao J, Xu X, Wan C, Liu T, Zheng Y, Ren S, Wang M, Chang G, Cronin SJF, Penninger JM, Jing T, Ou X, Rao S, Liu Z, Zhao XY
Nature communications 2022 Nov 28;13(1):7335
Nature communications 2022 Nov 28;13(1):7335
Betaine attenuate chronic restraint stress-induced changes in testicular damage and oxidative stress in male mice.
Meng X, Peng L, Xu J, Guo D, Cao W, Xu Y, Li S
Reproductive biology and endocrinology : RB&E 2022 May 21;20(1):80
Reproductive biology and endocrinology : RB&E 2022 May 21;20(1):80
Effects of testosterone on skin structure and factors related to androgen conversion and binding in Hetian sheep.
Shi R, Li S, Liu P, Guo L, Gong S, Wan Y
Tropical animal health and production 2022 Jun 27;54(4):218
Tropical animal health and production 2022 Jun 27;54(4):218
N-glycosylation of GDF15 abolishes its inhibitory effect on EGFR in AR inhibitor-resistant prostate cancer cells.
Wang R, Wen P, Yang G, Feng Y, Mi Y, Wang X, Zhu S, Chen YQ
Cell death & disease 2022 Jul 19;13(7):626
Cell death & disease 2022 Jul 19;13(7):626
Identification of endocrine-disrupting chemicals targeting the genes and pathways of genital anomalies in males.
Zhou X, Zhang X, Zhou X, Abulimiti G, Wang Y, Zhang Q, Cong R, Ji C, Luan J, Yao L, Yang J, Song N
Ecotoxicology and environmental safety 2022 Dec 1;247:114241
Ecotoxicology and environmental safety 2022 Dec 1;247:114241
Studying the nature of ascending-descending-floating-sinking of Chinese medicines based on gonadotropin-releasing hormone.
Yang FU, Peipei Y, Mengnan Z, Ying H, Liyuan G, Yaxin W, Xiaoke Z, Weisheng F
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2022 Aug;42(4):546-555
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2022 Aug;42(4):546-555
α-Terthienyl induces prostate cancer cell death through inhibiting androgen receptor expression.
Gan X, Huang H, Wen J, Liu K, Yang Y, Li X, Fang G, Liu Y, Wang X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Aug;152:113266
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Aug;152:113266
Cypermethrin inhibits proliferation of Sertoli cells through AR involving DAB2IP/PI3K/AKT signaling pathway in vitro.
Wang Q, Wang XX, Xie JF, Yao TT, Xu LL, Wang LS, Yu Y, Xu LC
Toxicology research 2022 Aug;11(4):583-591
Toxicology research 2022 Aug;11(4):583-591
RNF8 up-regulates AR/ARV7 action to contribute to advanced prostate cancer progression.
Zhou T, Wang S, Song X, Liu W, Dong F, Huo Y, Zou R, Wang C, Zhang S, Liu W, Sun G, Lin L, Zeng K, Dong X, Guo Q, Yi F, Wang Z, Li X, Jiang B, Cao L, Zhao Y
Cell death & disease 2022 Apr 15;13(4):352
Cell death & disease 2022 Apr 15;13(4):352
PRPF6 promotes androgen receptor/androgen receptor-variant 7 actions in castration-resistant prostate cancer cells.
Liu W, Wang C, Wang S, Zeng K, Wei S, Sun N, Sun G, Wang M, Zou R, Liu W, Lin L, Song H, Jin Z, Zhao Y
International journal of biological sciences 2021;17(1):188-203
International journal of biological sciences 2021;17(1):188-203
Icariin Ameliorates Diabetic Renal Tubulointerstitial Fibrosis by Restoring Autophagy via Regulation of the miR-192-5p/GLP-1R Pathway.
Jia Z, Wang K, Zhang Y, Duan Y, Xiao K, Liu S, Ding X
Frontiers in pharmacology 2021;12:720387
Frontiers in pharmacology 2021;12:720387
Expression of hormone receptors predicts survival and platinum sensitivity of high-grade serous ovarian cancer.
Tan J, Song C, Wang D, Hu Y, Liu D, Ma D, Gao Q
Bioscience reports 2021 May 28;41(5)
Bioscience reports 2021 May 28;41(5)
The function of BAP18 on modulation of androgen receptor action in luteinized granulosa cells from normal weight women with and without PCOS.
Tang T, Jiao J, Li D, Sun G, Lin L, Wang C, Wang S, Zou R, Liu W, Zhao Y, Wang X
Molecular and cellular endocrinology 2021 May 1;527:111228
Molecular and cellular endocrinology 2021 May 1;527:111228
Androgen Receptor Stimulates Hexokinase 2 and Induces Glycolysis by PKA/CREB Signaling in Hepatocellular Carcinoma.
Sun RF, Zhao CY, Chen S, Yu W, Zhou MM, Gao CR
Digestive diseases and sciences 2021 Mar;66(3):802-813
Digestive diseases and sciences 2021 Mar;66(3):802-813
Identification of low-frequency variants of UGT1A3 associated with bladder cancer risk by next-generation sequencing.
Zheng R, Du M, Ge Y, Gao F, Xin J, Lv Q, Qin C, Zhu Y, Gu C, Wang M, Zhu Q, Guo Z, Ben S, Chu H, Ye D, Zhang Z, Wang M
Oncogene 2021 Apr;40(13):2382-2394
Oncogene 2021 Apr;40(13):2382-2394
Pyruvate-Enriched Oral Rehydration Solution Improves Glucometabolic Disorders in the Kidneys of Diabetic db/db Mice.
Zhang XM, Deng H, Tong JD, Wang YZ, Ning XC, Yang XH, Zhou FQ, Jin HM
Journal of diabetes research 2020;2020:2817972
Journal of diabetes research 2020;2020:2817972
The Expression and Prognostic Significance of Claudin-8 and Androgen Receptor in Breast Cancer.
Zhang Y, Zheng A, Lu H, Jin Z, Peng Z, Jin F
OncoTargets and therapy 2020;13:3437-3448
OncoTargets and therapy 2020;13:3437-3448
Splicing factor PRPF6 upregulates oncogenic androgen receptor signaling pathway in hepatocellular carcinoma.
Song H, Sun N, Lin L, Wei S, Zeng K, Liu W, Wang C, Zhong X, Wang M, Wang S, Zhou B, Lv C, Liu W, Zhao Y
Cancer science 2020 Oct;111(10):3665-3678
Cancer science 2020 Oct;111(10):3665-3678
Co-transplantation with adipose-derived cells to improve parathyroid transplantation in a mice model.
Cui Q, Zhang D, Kong D, Tang J, Liao X, Yang Q, Ren J, Gong Y, Wu G
Stem cell research & therapy 2020 May 26;11(1):200
Stem cell research & therapy 2020 May 26;11(1):200
Androgen aggravates liver fibrosis by activation of NLRP3 inflammasome in CCl(4)-induced liver injury mouse model.
Ma X, Zhou Y, Qiao B, Jiang S, Shen Q, Han Y, Liu A, Chen X, Wei L, Zhou L, Zhao J
American journal of physiology. Endocrinology and metabolism 2020 May 1;318(5):E817-E829
American journal of physiology. Endocrinology and metabolism 2020 May 1;318(5):E817-E829
RNF6 promotes myeloma cell proliferation and survival by inducing glucocorticoid receptor polyubiquitination.
Ren Y, Xu X, Mao CY, Han KK, Xu YJ, Cao BY, Zhang ZB, Sethi G, Tang XW, Mao XL
Acta pharmacologica Sinica 2020 Mar;41(3):394-403
Acta pharmacologica Sinica 2020 Mar;41(3):394-403
Imidacloprid disrupts the endocrine system by interacting with androgen receptor in male mice.
Yuan X, Shen J, Zhang X, Tu W, Fu Z, Jin Y
The Science of the total environment 2020 Mar 15;708:135163
The Science of the total environment 2020 Mar 15;708:135163
Melatonin protects the mouse testis against heat-induced damage.
Zhang P, Zheng Y, Lv Y, Li F, Su L, Qin Y, Zeng W
Molecular human reproduction 2020 Feb 29;26(2):65-79
Molecular human reproduction 2020 Feb 29;26(2):65-79
ETA-mediated anti-TNF-α therapy ameliorates the phenotype of PCOS model induced by letrozole.
Lang Q, Yidong X, Xueguang Z, Sixian W, Wenming X, Tao Z
PloS one 2019;14(6):e0217495
PloS one 2019;14(6):e0217495
The preoperative neutrophil-to-lymphocyte ratio is not a marker of prostate cancer characteristics but is an independent predictor of biochemical recurrence in patients receiving radical prostatectomy.
Cao Z, Ji J, Zhang C, Wang F, Xu H, Yu Y, Sun Y
Cancer medicine 2019 Mar;8(3):1004-1012
Cancer medicine 2019 Mar;8(3):1004-1012
miR-323-3p regulates the steroidogenesis and cell apoptosis in polycystic ovary syndrome (PCOS) by targeting IGF-1.
Wang T, Liu Y, Lv M, Xing Q, Zhang Z, He X, Xu Y, Wei Z, Cao Y
Gene 2019 Jan 30;683:87-100
Gene 2019 Jan 30;683:87-100
Testosterone regulates 3T3-L1 pre-adipocyte differentiation and epididymal fat accumulation in mice through modulating macrophage polarization.
Ren X, Fu X, Zhang X, Chen S, Huang S, Yao L, Liu G
Biochemical pharmacology 2017 Sep 15;140:73-88
Biochemical pharmacology 2017 Sep 15;140:73-88
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The androgen receptor antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human androgen receptor. This antibody recognizes human,mouse,rat antigen. The androgen receptor antibody has been validated for the following applications: ELISA, WB analysis.
