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- Antibody Data
- Antigen structure
- References [59]
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- Validations
- Western blot [2]
- Immunocytochemistry [1]
- Immunoprecipitation [2]
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- Product number
- MA5-13423 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- Anti-Androgen Receptor Monoclonal Antibody (AR 441), Biotin
- Antibody type
- Monoclonal
- Antigen
- Synthetic peptide
- Description
- MA5-13423 targets Androgen Receptor in ICC/IF, IHC (P), IP, and WB applications and shows reactivity with human samples.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Biotin
- Isotype
- IgG
- Antibody clone number
- AR 441
- Vial size
- 500 µL
- Concentration
- 0.2 mg/mL
- Storage
- 4° C
Submitted references 'Neuroendocrine' middle ear adenomas: consistent expression of the transcription factor ISL1 further supports their neuroendocrine derivation.
Age at first childbirth and oral contraceptive use are associated with risk of androgen receptor-negative breast cancer: the Malmö Diet and Cancer Cohort.
Identification of a novel androgen receptor mutation in a family with multiple components compatible with the testicular dysgenesis syndrome.
Cytosolic phospholipase A2α sustains pAKT, pERK and AR levels in PTEN-null/mutated prostate cancer cells.
Androgen receptor in triple negative breast cancer.
The Fer tyrosine kinase acts as a downstream interleukin-6 effector of androgen receptor activation in prostate cancer.
Higher expression of androgen receptor is a significant predictor for better endocrine-responsiveness in estrogen receptor-positive breast cancers.
Integrative genomic, transcriptomic, and RNAi analysis indicates a potential oncogenic role for FAM110B in castration-resistant prostate cancer.
Correlation of AR, EGFR, and HER2 Expression Levels in Prostate Cancer: Immunohistochemical Analysis and Chromogenic In Situ Hybridization.
PTP1B is an androgen receptor-regulated phosphatase that promotes the progression of prostate cancer.
A transcriptional repressor co-regulatory network governing androgen response in prostate cancers.
Identification of CAD as an androgen receptor interactant and an early marker of prostate tumor recurrence.
Salinomycin inhibits prostate cancer growth and migration via induction of oxidative stress.
The 16p13.3 (PDPK1) Genomic Gain in Prostate Cancer: A Potential Role in Disease Progression.
The 16p13.3 (PDPK1) Genomic Gain in Prostate Cancer: A Potential Role in Disease Progression.
Homeodomain-interacting protein kinase 1 (HIPK1) expression in breast cancer tissues.
Expression of androgen receptor in breast cancer and its significance as a prognostic factor.
Arachidonic acid pathway members PLA2G7, HPGD, EPHX2, and CYP4F8 identified as putative novel therapeutic targets in prostate cancer.
C-28/I2 and T/C-28a2 chondrocytes as well as human primary articular chondrocytes express sex hormone and insulin receptors--Useful cells in study of cartilage metabolism.
Androgen receptor expression is significantly associated with better outcomes in estrogen receptor-positive breast cancers.
Prostate-regenerating capacity of cultured human adult prostate epithelial cells.
Metastatic breast cancer shows different immunohistochemical phenotype according to metastatic site.
Increased androgen receptor expression in serous carcinoma of the ovary is associated with an improved survival.
ERK regulates calpain 2-induced androgen receptor proteolysis in CWR22 relapsed prostate tumor cell lines.
Genome-wide analysis of androgen receptor binding and gene regulation in two CWR22-derived prostate cancer cell lines.
The PPARγ ligand ciglitazone regulates androgen receptor activation differently in androgen-dependent versus androgen-independent human prostate cancer cells.
Androgen-regulated expression of arginase 1, arginase 2 and interleukin-8 in human prostate cancer.
Food extracts consumed in Mediterranean countries and East Asia reduce protein concentrations of androgen receptor, phospho-protein kinase B, and phospho-cytosolic phospholipase A(2)alpha in human prostate cancer cells.
Proteomic interrogation of androgen action in prostate cancer cells reveals roles of aminoacyl tRNA synthetases.
Androgen receptor phosphorylation and activity are regulated by an association with protein phosphatase 1.
Increased expression of androgen receptor sensitizes prostate cancer cells to low levels of androgens.
High-throughput cell-based screening of 4910 known drugs and drug-like small molecules identifies disulfiram as an inhibitor of prostate cancer cell growth.
Over-expression of IkappaB-kinase-epsilon (IKKepsilon/IKKi) induces secretion of inflammatory cytokines in prostate cancer cell lines.
Co-assessment of cytoplasmic and nuclear androgen receptor location in prostate specimens: potential implications for prostate cancer development and prognosis.
Wnt pathway, angiogenetic and hormonal markers in sporadic and familial adenomatous polyposis-associated juvenile nasopharyngeal angiofibromas (JNA).
Overexpression of JKTBP1 induces androgen-independent LNCaP cell proliferation through activation of epidermal growth factor-receptor (EGF-R).
Defining the molecular action of HDAC inhibitors and synergism with androgen deprivation in ERG-positive prostate cancer.
Androgen regulation of the androgen receptor coregulators.
Androgen receptor blockade in experimental combination therapy of pancreatic cancer.
SIRNA-directed in vivo silencing of androgen receptor inhibits the growth of castration-resistant prostate carcinomas.
Evidence for calpain-mediated androgen receptor cleavage as a mechanism for androgen independence.
Exemestane's 17-hydroxylated metabolite exerts biological effects as an androgen.
Improved prediction of prostate cancer recurrence through systems pathology.
Interleukin-8 is a molecular determinant of androgen independence and progression in prostate cancer.
Expression of the epidermal growth factor system in endometrioid endometrial cancer.
Increased expression of CCAAT/enhancer-binding protein beta in proliferative inflammatory atrophy of the prostate: relation with the expression of COX-2, the androgen receptor, and presence of focal chronic inflammation.
GCP-mediated growth inhibition and apoptosis of prostate cancer cells via androgen receptor-dependent and -independent mechanisms.
The role of sialomucin CD164 (MGC-24v or endolyn) in prostate cancer metastasis.
Polymorphous adenocarcinoma of the breast. Report of three cases.
Androgen receptor immunostaining and androgen receptor messenger ribonucleic acid expression are increased in cremaster muscles associated with undescended testis.
Evaluation of neuroendocrine staining and androgen receptor expression in incidental prostatic adenocarcinoma: prognostic implications.
Development of androgen- and estrogen-responsive bioassays, members of a panel of human cell line-based highly selective steroid-responsive bioassays.
Expression of the epidermal growth factor system in human endometrium during the menstrual cycle.
Detection and expression of human BK virus sequences in neoplastic prostate tissues.
Computer based receptogram approach: an objective way of assessing immunohistochemistry of androgen receptor staining and its correlation with hormonal response in metastatic carcinoma of prostate.
Computer based receptogram approach: an objective way of assessing immunohistochemistry of androgen receptor staining and its correlation with hormonal response in metastatic carcinoma of prostate.
Androgen-independent prostate cancer is a heterogeneous group of diseases: lessons from a rapid autopsy program.
Characterization of a novel androgen receptor mutation in a relapsed CWR22 prostate cancer xenograft and cell line.
Functional analysis of 44 mutant androgen receptors from human prostate cancer.
Agaimy A, Lell M, Schaller T, Märkl B, Hornung J
Histopathology 2015 Jan;66(2):182-91
Histopathology 2015 Jan;66(2):182-91
Age at first childbirth and oral contraceptive use are associated with risk of androgen receptor-negative breast cancer: the Malmö Diet and Cancer Cohort.
Elebro K, Butt S, Dorkhan M, Jernström H, Borgquist S
Cancer causes & control : CCC 2014 Aug;25(8):945-57
Cancer causes & control : CCC 2014 Aug;25(8):945-57
Identification of a novel androgen receptor mutation in a family with multiple components compatible with the testicular dysgenesis syndrome.
Lottrup G, Jørgensen A, Nielsen JE, Jørgensen N, Duno M, Vinggaard AM, Skakkebæk NE, Rajpert-De Meyts E
The Journal of clinical endocrinology and metabolism 2013 Jun;98(6):2223-9
The Journal of clinical endocrinology and metabolism 2013 Jun;98(6):2223-9
Cytosolic phospholipase A2α sustains pAKT, pERK and AR levels in PTEN-null/mutated prostate cancer cells.
Hua S, Yao M, Vignarajan S, Witting P, Hejazi L, Gong Z, Teng Y, Niknami M, Assinder S, Richardson D, Dong Q
Biochimica et biophysica acta 2013 Jun;1831(6):1146-57
Biochimica et biophysica acta 2013 Jun;1831(6):1146-57
Androgen receptor in triple negative breast cancer.
McNamara KM, Yoda T, Takagi K, Miki Y, Suzuki T, Sasano H
The Journal of steroid biochemistry and molecular biology 2013 Jan;133:66-76
The Journal of steroid biochemistry and molecular biology 2013 Jan;133:66-76
The Fer tyrosine kinase acts as a downstream interleukin-6 effector of androgen receptor activation in prostate cancer.
Rocha J, Zouanat FZ, Zoubeidi A, Hamel L, Benidir T, Scarlata E, Brimo F, Aprikian A, Chevalier S
Molecular and cellular endocrinology 2013 Dec 5;381(1-2):140-9
Molecular and cellular endocrinology 2013 Dec 5;381(1-2):140-9
Higher expression of androgen receptor is a significant predictor for better endocrine-responsiveness in estrogen receptor-positive breast cancers.
Park S, Park HS, Koo JS, Yang WI, Kim SI, Park BW
Breast cancer research and treatment 2012 May;133(1):311-20
Breast cancer research and treatment 2012 May;133(1):311-20
Integrative genomic, transcriptomic, and RNAi analysis indicates a potential oncogenic role for FAM110B in castration-resistant prostate cancer.
Vainio P, Wolf M, Edgren H, He T, Kohonen P, Mpindi JP, Smit F, Verhaegh G, Schalken J, Perälä M, Iljin K, Kallioniemi O
The Prostate 2012 May 15;72(7):789-802
The Prostate 2012 May 15;72(7):789-802
Correlation of AR, EGFR, and HER2 Expression Levels in Prostate Cancer: Immunohistochemical Analysis and Chromogenic In Situ Hybridization.
Baek KH, Hong ME, Jung YY, Lee CH, Lee TJ, Park ES, Kim MK, Yoo JH, Lee SW
Cancer research and treatment : official journal of Korean Cancer Association 2012 Mar;44(1):50-6
Cancer research and treatment : official journal of Korean Cancer Association 2012 Mar;44(1):50-6
PTP1B is an androgen receptor-regulated phosphatase that promotes the progression of prostate cancer.
Lessard L, Labbé DP, Deblois G, Bégin LR, Hardy S, Mes-Masson AM, Saad F, Trotman LC, Giguère V, Tremblay ML
Cancer research 2012 Mar 15;72(6):1529-37
Cancer research 2012 Mar 15;72(6):1529-37
A transcriptional repressor co-regulatory network governing androgen response in prostate cancers.
Chng KR, Chang CW, Tan SK, Yang C, Hong SZ, Sng NY, Cheung E
The EMBO journal 2012 Jun 13;31(12):2810-23
The EMBO journal 2012 Jun 13;31(12):2810-23
Identification of CAD as an androgen receptor interactant and an early marker of prostate tumor recurrence.
Morin A, Fritsch L, Mathieu JR, Gilbert C, Guarmit B, Firlej V, Gallou-Kabani C, Vieillefond A, Delongchamps NB, Cabon F
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2012 Jan;26(1):460-7
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2012 Jan;26(1):460-7
Salinomycin inhibits prostate cancer growth and migration via induction of oxidative stress.
Ketola K, Hilvo M, Hyötyläinen T, Vuoristo A, Ruskeepää AL, Orešič M, Kallioniemi O, Iljin K
British journal of cancer 2012 Jan 3;106(1):99-106
British journal of cancer 2012 Jan 3;106(1):99-106
The 16p13.3 (PDPK1) Genomic Gain in Prostate Cancer: A Potential Role in Disease Progression.
Choucair KA, Guérard KP, Ejdelman J, Chevalier S, Yoshimoto M, Scarlata E, Fazli L, Sircar K, Squire JA, Brimo F, Cunha IW, Aprikian A, Gleave M, Lapointe J
Translational oncology 2012 Dec;5(6):453-60
Translational oncology 2012 Dec;5(6):453-60
The 16p13.3 (PDPK1) Genomic Gain in Prostate Cancer: A Potential Role in Disease Progression.
Choucair KA, Guérard KP, Ejdelman J, Chevalier S, Yoshimoto M, Scarlata E, Fazli L, Sircar K, Squire JA, Brimo F, Cunha IW, Aprikian A, Gleave M, Lapointe J
Translational oncology 2012 Dec;5(6):453-60
Translational oncology 2012 Dec;5(6):453-60
Homeodomain-interacting protein kinase 1 (HIPK1) expression in breast cancer tissues.
Park BW, Park S, Koo JS, Kim SI, Park JM, Cho JH, Park HS
Japanese journal of clinical oncology 2012 Dec;42(12):1138-45
Japanese journal of clinical oncology 2012 Dec;42(12):1138-45
Expression of androgen receptor in breast cancer and its significance as a prognostic factor.
Yu Q, Niu Y, Liu N, Zhang JZ, Liu TJ, Zhang RJ, Wang SL, Ding XM, Xiao XQ
Annals of oncology : official journal of the European Society for Medical Oncology 2011 Jun;22(6):1288-1294
Annals of oncology : official journal of the European Society for Medical Oncology 2011 Jun;22(6):1288-1294
Arachidonic acid pathway members PLA2G7, HPGD, EPHX2, and CYP4F8 identified as putative novel therapeutic targets in prostate cancer.
Vainio P, Gupta S, Ketola K, Mirtti T, Mpindi JP, Kohonen P, Fey V, Perälä M, Smit F, Verhaegh G, Schalken J, Alanen KA, Kallioniemi O, Iljin K
The American journal of pathology 2011 Feb;178(2):525-36
The American journal of pathology 2011 Feb;178(2):525-36
C-28/I2 and T/C-28a2 chondrocytes as well as human primary articular chondrocytes express sex hormone and insulin receptors--Useful cells in study of cartilage metabolism.
Claassen H, Schicht M, Brandt J, Reuse K, Schädlich R, Goldring MB, Guddat SS, Thate A, Paulsen F
Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft 2011 Feb 20;193(1):23-9
Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft 2011 Feb 20;193(1):23-9
Androgen receptor expression is significantly associated with better outcomes in estrogen receptor-positive breast cancers.
Park S, Koo JS, Kim MS, Park HS, Lee JS, Lee JS, Kim SI, Park BW, Lee KS
Annals of oncology : official journal of the European Society for Medical Oncology 2011 Aug;22(8):1755-62
Annals of oncology : official journal of the European Society for Medical Oncology 2011 Aug;22(8):1755-62
Prostate-regenerating capacity of cultured human adult prostate epithelial cells.
Yao M, Taylor RA, Richards MG, Sved P, Wong J, Eisinger D, Xie C, Salomon R, Risbridger GP, Dong Q
Cells, tissues, organs 2010;191(3):203-12
Cells, tissues, organs 2010;191(3):203-12
Metastatic breast cancer shows different immunohistochemical phenotype according to metastatic site.
Koo JS, Jung W, Jeong J
Tumori 2010 May-Jun;96(3):424-32
Tumori 2010 May-Jun;96(3):424-32
Increased androgen receptor expression in serous carcinoma of the ovary is associated with an improved survival.
Nodin B, Zendehrokh N, Brändstedt J, Nilsson E, Manjer J, Brennan DJ, Jirström K
Journal of ovarian research 2010 Jun 17;3:14
Journal of ovarian research 2010 Jun 17;3:14
ERK regulates calpain 2-induced androgen receptor proteolysis in CWR22 relapsed prostate tumor cell lines.
Chen H, Libertini SJ, Wang Y, Kung HJ, Ghosh P, Mudryj M
The Journal of biological chemistry 2010 Jan 22;285(4):2368-74
The Journal of biological chemistry 2010 Jan 22;285(4):2368-74
Genome-wide analysis of androgen receptor binding and gene regulation in two CWR22-derived prostate cancer cell lines.
Chen H, Libertini SJ, George M, Dandekar S, Tepper CG, Al-Bataina B, Kung HJ, Ghosh PM, Mudryj M
Endocrine-related cancer 2010 Dec;17(4):857-73
Endocrine-related cancer 2010 Dec;17(4):857-73
The PPARγ ligand ciglitazone regulates androgen receptor activation differently in androgen-dependent versus androgen-independent human prostate cancer cells.
Moss PE, Lyles BE, Stewart LV
Experimental cell research 2010 Dec 10;316(20):3478-88
Experimental cell research 2010 Dec 10;316(20):3478-88
Androgen-regulated expression of arginase 1, arginase 2 and interleukin-8 in human prostate cancer.
Gannon PO, Godin-Ethier J, Hassler M, Delvoye N, Aversa M, Poisson AO, Péant B, Alam Fahmy M, Saad F, Lapointe R, Mes-Masson AM
PloS one 2010 Aug 11;5(8):e12107
PloS one 2010 Aug 11;5(8):e12107
Food extracts consumed in Mediterranean countries and East Asia reduce protein concentrations of androgen receptor, phospho-protein kinase B, and phospho-cytosolic phospholipase A(2)alpha in human prostate cancer cells.
Singh J, Xie C, Yao M, Hua S, Vignarajan S, Jardine G, Hambly BD, Sved P, Dong Q
The Journal of nutrition 2010 Apr;140(4):786-91
The Journal of nutrition 2010 Apr;140(4):786-91
Proteomic interrogation of androgen action in prostate cancer cells reveals roles of aminoacyl tRNA synthetases.
Vellaichamy A, Sreekumar A, Strahler JR, Rajendiran T, Yu J, Varambally S, Li Y, Omenn GS, Chinnaiyan AM, Nesvizhskii AI
PloS one 2009 Sep 18;4(9):e7075
PloS one 2009 Sep 18;4(9):e7075
Androgen receptor phosphorylation and activity are regulated by an association with protein phosphatase 1.
Chen S, Kesler CT, Paschal BM, Balk SP
The Journal of biological chemistry 2009 Sep 18;284(38):25576-84
The Journal of biological chemistry 2009 Sep 18;284(38):25576-84
Increased expression of androgen receptor sensitizes prostate cancer cells to low levels of androgens.
Waltering KK, Helenius MA, Sahu B, Manni V, Linja MJ, Jänne OA, Visakorpi T
Cancer research 2009 Oct 15;69(20):8141-9
Cancer research 2009 Oct 15;69(20):8141-9
High-throughput cell-based screening of 4910 known drugs and drug-like small molecules identifies disulfiram as an inhibitor of prostate cancer cell growth.
Iljin K, Ketola K, Vainio P, Halonen P, Kohonen P, Fey V, Grafström RC, Perälä M, Kallioniemi O
Clinical cancer research : an official journal of the American Association for Cancer Research 2009 Oct 1;15(19):6070-8
Clinical cancer research : an official journal of the American Association for Cancer Research 2009 Oct 1;15(19):6070-8
Over-expression of IkappaB-kinase-epsilon (IKKepsilon/IKKi) induces secretion of inflammatory cytokines in prostate cancer cell lines.
Péant B, Diallo JS, Dufour F, Le Page C, Delvoye N, Saad F, Mes-Masson AM
The Prostate 2009 May 15;69(7):706-18
The Prostate 2009 May 15;69(7):706-18
Co-assessment of cytoplasmic and nuclear androgen receptor location in prostate specimens: potential implications for prostate cancer development and prognosis.
Diallo JS, Aldejmah A, Mouhim AF, Fahmy MA, Koumakpayi IH, Sircar K, Bégin LR, Mes-Masson AM, Saad F
BJU international 2008 May;101(10):1302-9
BJU international 2008 May;101(10):1302-9
Wnt pathway, angiogenetic and hormonal markers in sporadic and familial adenomatous polyposis-associated juvenile nasopharyngeal angiofibromas (JNA).
Ponti G, Losi L, Pellacani G, Rossi GB, Presutti L, Mattioli F, Villari D, Wannesson L, Alicandri Ciufelli M, Izzo P, De Rosa M, Marone P, Seidenari S
Applied immunohistochemistry & molecular morphology : AIMM 2008 Mar;16(2):173-8
Applied immunohistochemistry & molecular morphology : AIMM 2008 Mar;16(2):173-8
Overexpression of JKTBP1 induces androgen-independent LNCaP cell proliferation through activation of epidermal growth factor-receptor (EGF-R).
Wu YY, Li H, Lv XY, Wei Q, Li X, Liu XY, Zhou Q, Wei YQ
Cell biochemistry and function 2008 Jun;26(4):467-77
Cell biochemistry and function 2008 Jun;26(4):467-77
Defining the molecular action of HDAC inhibitors and synergism with androgen deprivation in ERG-positive prostate cancer.
Björkman M, Iljin K, Halonen P, Sara H, Kaivanto E, Nees M, Kallioniemi OP
International journal of cancer 2008 Dec 15;123(12):2774-81
International journal of cancer 2008 Dec 15;123(12):2774-81
Androgen regulation of the androgen receptor coregulators.
Urbanucci A, Waltering KK, Suikki HE, Helenius MA, Visakorpi T
BMC cancer 2008 Aug 1;8:219
BMC cancer 2008 Aug 1;8:219
Androgen receptor blockade in experimental combination therapy of pancreatic cancer.
Konduri S, Schwarz MA, Cafasso D, Schwarz RE
The Journal of surgical research 2007 Oct;142(2):378-86
The Journal of surgical research 2007 Oct;142(2):378-86
SIRNA-directed in vivo silencing of androgen receptor inhibits the growth of castration-resistant prostate carcinomas.
Compagno D, Merle C, Morin A, Gilbert C, Mathieu JR, Bozec A, Mauduit C, Benahmed M, Cabon F
PloS one 2007 Oct 10;2(10):e1006
PloS one 2007 Oct 10;2(10):e1006
Evidence for calpain-mediated androgen receptor cleavage as a mechanism for androgen independence.
Libertini SJ, Tepper CG, Rodriguez V, Asmuth DM, Kung HJ, Mudryj M
Cancer research 2007 Oct 1;67(19):9001-5
Cancer research 2007 Oct 1;67(19):9001-5
Exemestane's 17-hydroxylated metabolite exerts biological effects as an androgen.
Ariazi EA, Leitão A, Oprea TI, Chen B, Louis T, Bertucci AM, Sharma CG, Gill SD, Kim HR, Shupp HA, Pyle JR, Madrack A, Donato AL, Cheng D, Paige JR, Jordan VC
Molecular cancer therapeutics 2007 Nov;6(11):2817-27
Molecular cancer therapeutics 2007 Nov;6(11):2817-27
Improved prediction of prostate cancer recurrence through systems pathology.
Cordon-Cardo C, Kotsianti A, Verbel DA, Teverovskiy M, Capodieci P, Hamann S, Jeffers Y, Clayton M, Elkhettabi F, Khan FM, Sapir M, Bayer-Zubek V, Vengrenyuk Y, Fogarsi S, Saidi O, Reuter VE, Scher HI, Kattan MW, Bianco FJ, Wheeler TM, Ayala GE, Scardino PT, Donovan MJ
The Journal of clinical investigation 2007 Jul;117(7):1876-83
The Journal of clinical investigation 2007 Jul;117(7):1876-83
Interleukin-8 is a molecular determinant of androgen independence and progression in prostate cancer.
Araki S, Omori Y, Lyn D, Singh RK, Meinbach DM, Sandman Y, Lokeshwar VB, Lokeshwar BL
Cancer research 2007 Jul 15;67(14):6854-62
Cancer research 2007 Jul 15;67(14):6854-62
Expression of the epidermal growth factor system in endometrioid endometrial cancer.
Ejskjaer K, Sørensen BS, Poulsen SS, Forman A, Nexø E, Mogensen O
Gynecologic oncology 2007 Jan;104(1):158-67
Gynecologic oncology 2007 Jan;104(1):158-67
Increased expression of CCAAT/enhancer-binding protein beta in proliferative inflammatory atrophy of the prostate: relation with the expression of COX-2, the androgen receptor, and presence of focal chronic inflammation.
Wang W, Bergh A, Damber JE
The Prostate 2007 Aug 1;67(11):1238-46
The Prostate 2007 Aug 1;67(11):1238-46
GCP-mediated growth inhibition and apoptosis of prostate cancer cells via androgen receptor-dependent and -independent mechanisms.
Tepper CG, Vinall RL, Wee CB, Xue L, Shi XB, Burich R, Mack PC, de Vere White RW
The Prostate 2007 Apr 1;67(5):521-35
The Prostate 2007 Apr 1;67(5):521-35
The role of sialomucin CD164 (MGC-24v or endolyn) in prostate cancer metastasis.
Havens AM, Jung Y, Sun YX, Wang J, Shah RB, Bühring HJ, Pienta KJ, Taichman RS
BMC cancer 2006 Jul 21;6:195
BMC cancer 2006 Jul 21;6:195
Polymorphous adenocarcinoma of the breast. Report of three cases.
Asioli S, Marucci G, Ficarra G, Stephens M, Foschini MP, Ellis IO, Eusebi V
Virchows Archiv : an international journal of pathology 2006 Jan;448(1):29-34
Virchows Archiv : an international journal of pathology 2006 Jan;448(1):29-34
Androgen receptor immunostaining and androgen receptor messenger ribonucleic acid expression are increased in cremaster muscles associated with undescended testis.
Tanyel FC, Yüzbaşioğlu A, Kocaefe C, Orhan D, Ozgüç M
Urology 2006 Apr;67(4):855-8
Urology 2006 Apr;67(4):855-8
Evaluation of neuroendocrine staining and androgen receptor expression in incidental prostatic adenocarcinoma: prognostic implications.
Theodoropoulos VE, Tsigka A, Mihalopoulou A, Tsoukala V, Lazaris AC, Patsouris E, Ghikonti I
Urology 2005 Oct;66(4):897-902
Urology 2005 Oct;66(4):897-902
Development of androgen- and estrogen-responsive bioassays, members of a panel of human cell line-based highly selective steroid-responsive bioassays.
Sonneveld E, Jansen HJ, Riteco JA, Brouwer A, van der Burg B
Toxicological sciences : an official journal of the Society of Toxicology 2005 Jan;83(1):136-48
Toxicological sciences : an official journal of the Society of Toxicology 2005 Jan;83(1):136-48
Expression of the epidermal growth factor system in human endometrium during the menstrual cycle.
Ejskjaer K, Sørensen BS, Poulsen SS, Mogensen O, Forman A, Nexø E
Molecular human reproduction 2005 Aug;11(8):543-51
Molecular human reproduction 2005 Aug;11(8):543-51
Detection and expression of human BK virus sequences in neoplastic prostate tissues.
Das D, Shah RB, Imperiale MJ
Oncogene 2004 Sep 16;23(42):7031-46
Oncogene 2004 Sep 16;23(42):7031-46
Computer based receptogram approach: an objective way of assessing immunohistochemistry of androgen receptor staining and its correlation with hormonal response in metastatic carcinoma of prostate.
Nabi G, Seth A, Dinda AK, Gupta NP
Journal of clinical pathology 2004 Feb;57(2):146-50
Journal of clinical pathology 2004 Feb;57(2):146-50
Computer based receptogram approach: an objective way of assessing immunohistochemistry of androgen receptor staining and its correlation with hormonal response in metastatic carcinoma of prostate.
Nabi G, Seth A, Dinda AK, Gupta NP
Journal of clinical pathology 2004 Feb;57(2):146-50
Journal of clinical pathology 2004 Feb;57(2):146-50
Androgen-independent prostate cancer is a heterogeneous group of diseases: lessons from a rapid autopsy program.
Shah RB, Mehra R, Chinnaiyan AM, Shen R, Ghosh D, Zhou M, Macvicar GR, Varambally S, Harwood J, Bismar TA, Kim R, Rubin MA, Pienta KJ
Cancer research 2004 Dec 15;64(24):9209-16
Cancer research 2004 Dec 15;64(24):9209-16
Characterization of a novel androgen receptor mutation in a relapsed CWR22 prostate cancer xenograft and cell line.
Tepper CG, Boucher DL, Ryan PE, Ma AH, Xia L, Lee LF, Pretlow TG, Kung HJ
Cancer research 2002 Nov 15;62(22):6606-14
Cancer research 2002 Nov 15;62(22):6606-14
Functional analysis of 44 mutant androgen receptors from human prostate cancer.
Shi XB, Ma AH, Xia L, Kung HJ, de Vere White RW
Cancer research 2002 Mar 1;62(5):1496-502
Cancer research 2002 Mar 1;62(5):1496-502
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Western blot of Androgen Receptor using Androgen Receptor Monoclonal Antibody (Product # MA5-13423) on LNCaP Cells.
- Conjugate
- Biotin
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Western blot analysis of Androgen Receptor was performed by loading 50 µg of LNCaP, MCF7, HeLa, and DU145 whole cell lysates, and 10 µL of PageRuler Prestained Protein Ladder (Product # 26616) onto a 4-20% Tris-HCl polyacrylamide gel. Proteins were transferred to a PVDF membrane and blocked with StartingBlock T20 (Product # 37543) for 1 hour. The membrane was probed with a biotinylated Androgen Receptor monoclonal antibody (Product # MA5-13423) at a dilution of 1:100 overnight at 4C on a rocking platform, washed in TBS-0.1%Tween-20, followed by Streptavidin-HRP (Product # 21126) at a dilution of 1:20,000 for 30 minutes at room temperature. Chemiluminescent detection was performed using SuperSignal West Dura (Product # 34075). Images were acquired on a Thermo Scientific myECL Imager (Product # 62236).
- Conjugate
- Biotin
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of Androgen Receptor (green) in LNCaP (right panel) and negative control U2OS cells (left panel). Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 10 minutes at room temperature. Cells were blocked with 1% Blocker BSA (Product # 37525) for 15 minutes at room temperature. Cells were probed with a biotinylated Androgen Receptor monoclonal antibody (Product # MA5-13423) at a dilution of 1:50 for at least 1 hour at room temperature, washed with PBS, and incubated with a DyLight 488-conjugated Streptavidin (Product # 21832) at a dilution of 1:400 for 1 hour at room temperature. F-Actin (red) was stained with DyLight-554 Phalloidin (Product # 21834) and nuclei (blue) were stained with Hoechst 33342 dye (Product # 62249). Images were taken on a Thermo Scientific ToxInsight Instrument at 20X magnification.
- Conjugate
- Biotin
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunoprecipitation of Androgen Receptor using Androgen Receptor Monoclonal Antibody (Product # MA5-13423) on denatured Human LNCaP Cells.
- Conjugate
- Biotin
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunoprecipitation of Androgen Receptor was performed on LNCaP cells. Antigen-antibody complexes were formed by incubating 250ug of LNCaP whole cell lysate with 2ug of a biotinylated Androgen Receptor monoclonal antibody (Product # MA5-13423) overnight on a rocking platform at 4C. The immune complexes were captured on 50ul Streptavidin Agarose (Product # 20347), washed extensively, and eluted with 5X Lane Marker Reducing Sample Buffer (Product # 39000). Eluted sample and 20ug of LNCaP whole cell lysate (loading control) were resolved on a 4-20% Tris-HCl polyacrylamide gel, transferred to a PVDF membrane, and blocked with StartingBlock T20 (Product # 37543) for 1 hour. The membrane was probed with an Androgen Receptor polyclonal antibody (Product # PA5-16750) at a dilution of 1:200 overnight rotating at 4¡C, washed in TBST, and probed with an HRP-conjugated goat anti-rabbit IgG (Product # 31460) at a dilution of 1:20,000 for 1 hour. Chemiluminescent detection was performed using SuperSignal West Dura (Product # 34075). Images were acquired on a Thermo Scientific myECL Imager (Product # 62236).
