FNab04620

antibody from FineTest Biotech

Targeting: KLHL22 FLJ14360, KELCHL

Western blot

ELISA

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Validation data

Product number: FNab04620 - Provider product page
Provider: FineTest Biotech
Product name: KLHL22 antibody
Antibody type: Polyclonal
Antigen: Recombinant protein fragment
Description: Substrate-specific adapter of a BCR(BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for chromosome alignment and localization of PLK1 at kinetochores. The BCR(KLHL22) ubiquitin ligase complex mediates monoubiquitination of PLK1, leading to PLK1 dissociation from phosphoreceptor proteins and subsequent removal from kinetochores, allowing silencing of the spindle assembly checkpoint(SAC) and chromosome segregation. Monoubiquitination of PLK1 does not lead to PLK1 degradation.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: kelch-like 22(Drosophila)
Epitope: IgG
Isotype: IgG
Vial size: 100¦Ìg
Concentration: Immunogen affinity purified
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

KLHL22 protein structure - FNab04620 shown in red.