Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- MAB8272 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Mouse Monoclonal Bcl-2 Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects human Bcl-2 in direct ELISAs and Western blots. In direct ELISAs, approximately 25-40% cross-reactivity with recombinant mouse (rm) Bcl-2 is observed and no cross-reactivity with recombinant human BCL2L12 is observed. In Western blots, 100% cross-reactivity with rmBcl-2 is observed.
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 ug
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Submitted references Metformin exhibited anticancer activity by lowering cellular cholesterol content in breast cancer cells.
Dexmedetomidine protects the developing rat brain against the neurotoxicity wrought by sevoflurane: role of autophagy and Drp1-Bax signaling.
FK506 Attenuates the MRP1-Mediated Chemoresistant Phenotype in Glioblastoma Stem-Like Cells.
Exosomes derived from human umbilical cord mesenchymal stem cells improve myocardial repair via upregulation of Smad7.
Hepatoprotective effect of calculus bovis sativus on nonalcoholic fatty liver disease in mice by inhibiting oxidative stress and apoptosis of hepatocytes.
Sharma A, Bandyopadhayaya S, Chowdhury K, Sharma T, Maheshwari R, Das A, Chakrabarti G, Kumar V, Mandal CC
PloS one 2019;14(1):e0209435
PloS one 2019;14(1):e0209435
Dexmedetomidine protects the developing rat brain against the neurotoxicity wrought by sevoflurane: role of autophagy and Drp1-Bax signaling.
Shan Y, Sun S, Yang F, Shang N, Liu H
Drug design, development and therapy 2018;12:3617-3624
Drug design, development and therapy 2018;12:3617-3624
FK506 Attenuates the MRP1-Mediated Chemoresistant Phenotype in Glioblastoma Stem-Like Cells.
Torres Á, Arriagada V, Erices JI, Toro MLÁ, Rocha JD, Niechi I, Carrasco C, Oyarzún C, Quezada C
International journal of molecular sciences 2018 Sep 11;19(9)
International journal of molecular sciences 2018 Sep 11;19(9)
Exosomes derived from human umbilical cord mesenchymal stem cells improve myocardial repair via upregulation of Smad7.
Wang XL, Zhao YY, Sun L, Shi Y, Li ZQ, Zhao XD, Xu CG, Ji HG, Wang M, Xu WR, Zhu W
International journal of molecular medicine 2018 May;41(5):3063-3072
International journal of molecular medicine 2018 May;41(5):3063-3072
Hepatoprotective effect of calculus bovis sativus on nonalcoholic fatty liver disease in mice by inhibiting oxidative stress and apoptosis of hepatocytes.
He W, Xu Y, Zhang C, Lu J, Li J, Xiang D, Yang J, Chang M, Liu D
Drug design, development and therapy 2017;11:3449-3460
Drug design, development and therapy 2017;11:3449-3460
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Detection of Human, Mouse, and Rat Bcl-2 by Western Blot. Detection of Human, Mouse, and Rat Bcl-2 by Western Blot.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Bcl-2 in Human Lymphoma. Bcl-2 in Human Lymphoma.