Antibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- V2008 - Provider product page
- Provider
- NSJ Bioreagents
- Product name
- Bcl-2 Antibody
- Antibody type
- Monoclonal
- Antigen
- A synthetic peptide, aa 41-54 (GAAPAPGIFSSQPG-Cys) of human Bcl-2 protein was used as the immunogen for this antibody.
- Description
- Protein G purified antibody
- Reactivity
- Human, Simian
- Host
- Mouse
- Conjugate
- Unconjugated
- Antibody clone number
- 8C8
- Vial size
- 20 µg, 100 µg (with sodium azide), 100 µg (without sodium azide), 7 ml (prediluted for IHC use, if applicable)
- Storage
- Store the Bcl-2 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Submitted references Pleomorphic carcinoma of breast: a case report and review of literature.
Spindle cell rhabdomyosarcoma of the retroperitoneum: an unusual case developed in a pregnant woman but obscured by pregnancy.
Immunohistochemistry with apoptotic-antiapoptotic proteins (p53, p21, bax, bcl-2), c-kit, telomerase, and metallothionein as a diagnostic aid in benign, borderline, and malignant serous and mucinous ovarian tumors.
Inhibition of telomerase activity and induction of apoptosis by curcumin in K-562 cells.
Apoptosis modulatory activities of transiently expressed Bcl-2: roles in cytochrome C release and Bax regulation.
Prognostic factors in transitional cell cancer of the bladder: an emerging role for Bcl-2 and p53.
Movement of Bax from the cytosol to mitochondria during apoptosis.
Tang H, Liu F, Li H, Huang X, Zhao T
International journal of clinical and experimental pathology 2014;7(8):5215-20
International journal of clinical and experimental pathology 2014;7(8):5215-20
Spindle cell rhabdomyosarcoma of the retroperitoneum: an unusual case developed in a pregnant woman but obscured by pregnancy.
Yu L, Yang SJ
International journal of clinical and experimental pathology 2014;7(8):4904-12
International journal of clinical and experimental pathology 2014;7(8):4904-12
Immunohistochemistry with apoptotic-antiapoptotic proteins (p53, p21, bax, bcl-2), c-kit, telomerase, and metallothionein as a diagnostic aid in benign, borderline, and malignant serous and mucinous ovarian tumors.
Ozer H, Yenicesu G, Arici S, Cetin M, Tuncer E, Cetin A
Diagnostic pathology 2012 Sep 20;7:124
Diagnostic pathology 2012 Sep 20;7:124
Inhibition of telomerase activity and induction of apoptosis by curcumin in K-562 cells.
Chakraborty S, Ghosh U, Bhattacharyya NP, Bhattacharya RK, Roy M
Mutation research 2006 Apr 11;596(1-2):81-90
Mutation research 2006 Apr 11;596(1-2):81-90
Apoptosis modulatory activities of transiently expressed Bcl-2: roles in cytochrome C release and Bax regulation.
Hou Q, Cymbalyuk E, Hsu SC, Xu M, Hsu YT
Apoptosis : an international journal on programmed cell death 2003 Dec;8(6):617-29
Apoptosis : an international journal on programmed cell death 2003 Dec;8(6):617-29
Prognostic factors in transitional cell cancer of the bladder: an emerging role for Bcl-2 and p53.
Ong F, Moonen LM, Gallee MP, ten Bosch C, Zerp SF, Hart AA, Bartelink H, Verheij M
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2001 Nov;61(2):169-75
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2001 Nov;61(2):169-75
Movement of Bax from the cytosol to mitochondria during apoptosis.
Wolter KG, Hsu YT, Smith CL, Nechushtan A, Xi XG, Youle RJ
The Journal of cell biology 1997 Dec 1;139(5):1281-92
The Journal of cell biology 1997 Dec 1;139(5):1281-92
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Supportive validation
- Submitted by
- NSJ Bioreagents (provider)
- Main image
- Experimental details
- Western blot testing of human samples with Bcl-2 antibody (8C8).
Supportive validation
- Submitted by
- NSJ Bioreagents (provider)
- Main image
- Experimental details
- IHC testing of human tonsil stained with Bcl-2 antibody (8C8).Note cell membrane and cytoplasmic staining.