Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- NBP2-47853-0.1mg - Provider product page
- Provider
- Novus Biologicals
- Product name
- Mouse Monoclonal Bcl-2 Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified. This antibody recognizes a protein of 25-26kDa, identified as the bcl-2 alpha oncoprotein. It shows no cross-reaction with Bcl-x or Bax protein. Expression of bcl-2 alpha oncoprotein inhibits the programmed cell death (apoptosis). In most follicular lymphomas, neoplastic germinal centers express high levels of bcl-2 alpha protein, whereas the normal or hyperplastic germinal centers are negative. Consequently, this antibody is valuable when distinguishing between reactive and neoplastic follicular proliferation in lymph node biopsies. It may also be used in distinguishing between those follicular lymphomas that express bcl-2 protein and the small number in which the neoplastic cells are bcl-2 negative.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 1.0 mg/ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: Bcl-2 Antibody (BCL2/782 + BCL2/796) - Azide and BSA Free [NBP2-47853] - MCF-7 cell lysate using Bcl-2 Monoclonal Antibody (BCL2/782 + BCL2/796).
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Bcl-2 Antibody (BCL2/782 + BCL2/796) - Azide and BSA Free [NBP2-47853] - Human non-Hodgkin's lymphoma stained with Bcl-2 Monoclonal Antibody (BCL2/782 + BCL2/796).
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Bcl-2 Antibody (BCL2/782 + BCL2/796) - Azide and BSA Free [NBP2-47853] - Human Melanoma stained with Bcl-2 Monoclonal Antibody (BCL2/782 + BCL2/796).