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- References [4]
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- Product number
- MHBCL04 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- Bcl-2 Monoclonal Antibody (100), PE
- Antibody type
- Monoclonal
- Antigen
- Other
- Description
- R-phycoerythrin (PE) is a stable and highly soluble phycobiliprotein which provides maximal absorbance and fluorescence without susceptibility to internal or external fluorescence quenching, thus providing an exceptional quantum yields and molar extinction coefficients.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Yellow dye
- Isotype
- IgG
- Antibody clone number
- 100
- Vial size
- 500 µL
- Storage
- 4° C, store in dark
Submitted references Trypanosoma cruzi-specific IFN-γ-producing cells in chronic Chagas disease associate with a functional IL-7/IL-7R axis.
JAK/STAT pathway inhibition overcomes IL7-induced glucocorticoid resistance in a subset of human T-cell acute lymphoblastic leukemias.
CD4(+) T regulatory cells are more resistant to DNA damage compared to CD4(+) T effector cells as revealed by flow cytometric analysis.
Overexpression of BCL2 enhances survival of human embryonic stem cells during stress and obviates the requirement for serum factors.
Natale MA, Cesar G, Alvarez MG, Castro Eiro MD, Lococo B, Bertocchi G, Albareda MC, Laucella SA
PLoS neglected tropical diseases 2018 Dec;12(12):e0006998
PLoS neglected tropical diseases 2018 Dec;12(12):e0006998
JAK/STAT pathway inhibition overcomes IL7-induced glucocorticoid resistance in a subset of human T-cell acute lymphoblastic leukemias.
Delgado-Martin C, Meyer LK, Huang BJ, Shimano KA, Zinter MS, Nguyen JV, Smith GA, Taunton J, Winter SS, Roderick JR, Kelliher MA, Horton TM, Wood BL, Teachey DT, Hermiston ML
Leukemia 2017 Dec;31(12):2568-2576
Leukemia 2017 Dec;31(12):2568-2576
CD4(+) T regulatory cells are more resistant to DNA damage compared to CD4(+) T effector cells as revealed by flow cytometric analysis.
Winzler C, Fantinato M, Giordan M, Calore E, Basso G, Messina C
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2011 Nov;79(11):903-11
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2011 Nov;79(11):903-11
Overexpression of BCL2 enhances survival of human embryonic stem cells during stress and obviates the requirement for serum factors.
Ardehali R, Inlay MA, Ali SR, Tang C, Drukker M, Weissman IL
Proceedings of the National Academy of Sciences of the United States of America 2011 Feb 22;108(8):3282-7
Proceedings of the National Academy of Sciences of the United States of America 2011 Feb 22;108(8):3282-7
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- NULL
- Conjugate
- Yellow dye
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Fig 6 Altered STAT5 downstream events in IFN-gamma nonproducers. Bcl-2 and CD25 expression was determined using flow cytometry analysis after 48 h of in vitro stimulation with rhIL-7. Each symbol represents the IL-7-induced CD25 expression after (Delta % CD25 + ) (A-B) or the basal CD25 + expression (C-D). The difference in Bcl-2 mean fluorescence intensity (MFI) between IL-7-stimulated and unstimulated cell cultures (E-F) or the basal Bcl-2 expression (G-H) in CD4 + (left) or CD8 + (right) T cells. Horizontal lines indicate median values. Black symbols indicate subjects treated with benznidazole. Based on the ELISPOT assay, responses of T . cruzi -infected subjects were used to determine the IFN-gamma producers (P) and IFN-gamma nonproducers (NP), as described in Materials and Methods. Comparisons between P and NP for each clinical group and uninfected subjects were performed using ANOVA followed by Dunn's multiple comparisons test. * p
- Conjugate
- Yellow dye
