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- Antibody Data
- Antigen structure
- References [160]
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- Product number
- A00040-2 - Provider product page
- Provider
- Boster Biological Technology
- Product name
- Anti-Bcl-2/BCL2 Antibody Picoband™
- Antibody type
- Polyclonal
- Description
- Polyclonal antibody for Bcl-2/BCL2 detection. Host: Rabbit.Size: 100μg/vial. Tested applications: ELISA. Reactive species: Human. Bcl-2/BCL2 information: Subcellular Localization: Mitochondrion outer membrane; Tissue Specificity: Expressed in a variety of tissues.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Vial size
- 100μg/vial
- Concentration
- 0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
- Storage
- At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquoted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
- Handling
- Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Submitted references Chondroitin sulfate-modified antiangiogenic peptide conjugate induces cell apoptosis via the mitochondria-mediated pathway to perform antitumor activity.
Protopanaxadiol Targeting Membrane Induces HepG2 Cell Apoptosis Via Raft-like Formation and Tubulation Disruption.
Circ_0002331 Interacts with ELAVL1 to Improve ox-LDL-Induced Vascular Endothelial Cell Dysfunction via Regulating CCND2 mRNA Stability.
Adiponectin attenuates H2O2-induced apoptosis in chicken skeletal myoblasts through the lysosomal-mitochondrial axis.
Hepatitis E virus causes apoptosis of ovarian cells in hens and resulting in a decrease in egg production.
A Testlet Diagnostic Classification Model with Attribute Hierarchies.
The combined analgesic, sedative, and anti-gastric cancer mechanisms of Tinospora sagittata var. yunnanensis (S. Y. Hu) H. S. Lo based on integrated ethnopharmacological data.
Modified CFBP-bFGF targeting to ischemic brain promoted the functional recovery of cerebral ischemia.
Rutaecarpine Ameliorates Murine N-Methyl-N'-Nitro-N-Nitrosoguanidine-Induced Chronic Atrophic Gastritis by Sonic Hedgehog Pathway.
lncRNA HOTTIP Recruits EZH2 to Inhibit PTEN Expression and Participates in IM Resistance in Chronic Myeloid Leukemia.
Soluble Epoxide Hydrolase Inhibition Protected against Diabetic Cardiomyopathy through Inducing Autophagy and Reducing Apoptosis Relying on Nrf2 Upregulation and Transcription Activation.
Glabridin from Glycyrrhiza glabra Possesses a Therapeutic Role against Keloid via Attenuating PI3K/Akt and Transforming Growth Factor-β1/SMAD Signaling Pathways.
DNMT1-mediated demethylation of lncRNA MEG3 promoter suppressed breast cancer progression by repressing Notch1 signaling pathway.
Psoralidin protects against cerebral hypoxia/reoxygenation injury: Role of GAS6/Axl signaling.
MiR-153 downregulation alleviates PTSD-like behaviors and reduces cell apoptosis by upregulating the Sigma-1 receptor in the hippocampus of rats exposed to single-prolonged stress.
Preparation of Nereid oligopeptide and investigation of the mechanism underlying the induction of apoptosis in human lung cancer H1299 cells.
Silibinin protects against sepsis and septic myocardial injury in an NR1H3-dependent pathway.
Protective effects and mechanisms of lycorine against adriamycin-induced cardiotoxicity.
Dietary Calcium Alleviates Fluorine-Induced Liver Injury in Rats by Mitochondrial Apoptosis Pathway.
Metformin inhibits the tumor-promoting effect of low-dose resveratrol, and enhances the anti-tumor activity of high-dose resveratrol by increasing its reducibility in triple negative breast cancer.
Tunicamycin Induces Hepatic Stellate Cell Apoptosis Through Calpain-2/Ca(2 +)-Dependent Endoplasmic Reticulum Stress Pathway.
Mechanism of Action of Xiaoyao San in Treatment of Ischemic Stroke is Related to Anti-Apoptosis and Activation of PI3K/Akt Pathway.
SIRT1/PGC-1α signaling activation by mangiferin attenuates cerebral hypoxia/reoxygenation injury in neuroblastoma cells.
Continuous artificial light at night exacerbates diisononyl phthalate-induced learning and memory impairment in mice: Toxicological evidence.
Insulin injections inhibits PTZ-induced mitochondrial dysfunction, oxidative stress and neurological deficits via the SIRT1/PGC-1α/SIRT3 pathway.
Protective Effect of GM1 Attenuates Hippocampus and Cortex Apoptosis After Ketamine Exposure in Neonatal Rat via PI3K/AKT/GSK3β Pathway.
TRB3 mediates vascular remodeling by activating the MAPK signaling pathway in hypoxic pulmonary hypertension.
CircHIPK3 regulates the autophagy and apoptosis of hypoxia/reoxygenation-stimulated cardiomyocytes via the miR-20b-5p/ATG7 axis.
Hydroxy-α-sanshool Possesses Protective Potentials on H(2)O(2)-Stimulated PC12 Cells by Suppression of Oxidative Stress-Induced Apoptosis through Regulation of PI3K/Akt Signal Pathway.
CircPOSTN/miR-361-5p/TPX2 axis regulates cell growth, apoptosis and aerobic glycolysis in glioma cells.
Schizandrol A protects against Aβ(1-42)-induced autophagy via activation of PI3K/AKT/mTOR pathway in SH-SY5Y cells and primary hippocampal neurons.
COX-2-PGE(2) signaling pathway contributes to hippocampal neuronal injury and cognitive impairment in PTZ-kindled epilepsy mice.
Aptamer-protamine-siRNA nanoparticles in targeted therapy of ErbB3 positive breast cancer cells.
Antihypertensive and renal protective effect of Shunaoxin pill combined with captopril on spontaneous hypertension rats.
The PI3K/Akt and NF-κB signaling pathways are involved in the protective effects of Lithocarpus polystachyus (sweet tea) on APAP-induced oxidative stress injury in mice.
Neuroprotective effects of miR-532-5p against ischemic stroke.
Lactobacillus rhamnosus FLRH93 protects against intestinal damage in mice induced by 5-fluorouracil.
Icariin improves cognitive deficits by reducing the deposition of β-amyloid peptide and inhibition of neurons apoptosis in SAMP8 mice.
Antioxidant preconditioning improves therapeutic outcomes of adipose tissue-derived mesenchymal stem cells through enhancing intrahepatic engraftment efficiency in a mouse liver fibrosis model.
Crocin protects against cardiotoxicity induced by doxorubicin through TLR-2/NF-κB signal pathway in vivo and vitro.
[6]-Gingerol Ameliorates ISO-Induced Myocardial Fibrosis by Reducing Oxidative Stress, Inflammation, and Apoptosis through Inhibition of TLR4/MAPKs/NF-κB Pathway.
The study of effect and mechanism of 630-nm laser on human lung adenocarcinoma cell xenograft model in nude mice mediated by hematoporphyrin derivatives.
MiR-183-5p protects rat hearts against myocardial ischemia/reperfusion injury through targeting VDAC1.
MicroRNA-375 exacerbates knee osteoarthritis through repressing chondrocyte autophagy by targeting ATG2B.
Alteronol Enhances the Anti-tumor Activity and Reduces the Toxicity of High-Dose Adriamycin in Breast Cancer.
Trimetazidine Attenuates Exhaustive Exercise-Induced Myocardial Injury in Rats via Regulation of the Nrf2/NF-κB Signaling Pathway.
Elimination of Intracellular Calcium Overload by BAPTA-AM-Loaded Liposomes: A Promising Therapeutic Agent for Acute Liver Failure.
Effects of rosmarinic acid on immunoregulatory activity and hepatocellular carcinoma cell apoptosis in H22 tumor-bearing mice.
Preoperative vitamin-rich carbohydrate loading alleviates postoperative cognitive dysfunction in aged rats.
Noncoding transcribed ultraconserved region (T-UCR) UC.48+ is a novel regulator of high-fat diet induced myocardial ischemia/reperfusion injury.
Inotodiol inhibits cells migration and invasion and induces apoptosis via p53-dependent pathway in HeLa cells.
LaSota Strain Expressing The Rabies Virus Glycoprotein (rL-RVG) Suppresses Gastric Cancer by Inhibiting the Alpha 7 Nicotinic Acetylcholine Receptor (α7 nAChR)/Phosphoinositide 3-Kinase (PI3K)/AKT Pathway.
MiR-199a-5p regulates rat liver regeneration and hepatocyte proliferation by targeting TNF-α TNFR1/TRADD/CASPASE8/CASPASE3 signalling pathway.
Protective effects of pentadecapeptide derived from Cyclaina sinensis against cyclophosphamide-induced hepatotoxicity.
Treatment with MQA, a Derivative of Caffeoylquinic Acid, Provides Neuroprotective Effects against Cerebral Ischemia Through Suppression of the p38 Pathway and Oxidative Stress in Rats.
Exosomes Derived from miR-214-Enriched Bone Marrow-Derived Mesenchymal Stem Cells Regulate Oxidative Damage in Cardiac Stem Cells by Targeting CaMKII.
Neural Stem Cell-Conditioned Medium Ameliorated Cerebral Ischemia-Reperfusion Injury in Rats.
Perfluorooctanoic acid exposure during pregnancy alters the apoptosis of uterine cells in pregnant mice.
RRM2 promotes the progression of human glioblastoma.
The protective effects of maltol on cisplatin-induced nephrotoxicity through the AMPK-mediated PI3K/Akt and p53 signaling pathways.
Insight into the negative impact of ionic liquid: A cytotoxicity mechanism of 1-methyl-3-octylimidazolium bromide.
Platycodin D protects acetaminophen-induced hepatotoxicity by inhibiting hepatocyte MAPK pathway and apoptosis in C57BL/6J mice.
Role of capsaicin sensitive sensory nerves in ischemia reperfusion-induced acute kidney injury in rats.
Adolescent cocaine exposure induces prolonged synaptic modifications in medial prefrontal cortex of adult rats.
Improvement of Cisplatin-induced renal dysfunction by Schisandra chinensis stems via anti-inflammation and anti-apoptosis effects.
Neuroprotective effects of a triple GLP-1/GIP/glucagon receptor agonist in the APP/PS1 transgenic mouse model of Alzheimer's disease.
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Lithium chloride (LiCl) induced autophagy and downregulated expression of transforming growth factor β-induced protein (TGFBI) in granular corneal dystrophy.
PSMB8 regulates glioma cell migration, proliferation, and apoptosis through modulating ERK1/2 and PI3K/AKT signaling pathways.
Acute downregulation of miR-199a attenuates sepsis-induced acute lung injury by targeting SIRT1.
Inhibition of glioblastoma growth and invasion by (125)I brachytherapy in rat glioma model.
Lipoxin A4 pretreatment mitigates skeletal muscle ischemia-reperfusion injury in rats.
Protective Effects of Sodium (±)-5-Bromo-2-(α-Hydroxypentyl) Benzoate in a Rodent Model of Global Cerebral Ischemia.
Celastrol Attenuates Multiple Sclerosis and Optic Neuritis in an Experimental Autoimmune Encephalomyelitis Model.
MicroRNA-210 alleviates oxidative stress-associated cardiomyocyte apoptosis by regulating BNIP3.
Antitumorpharmacological mechanism of the oral liquid of Poriacocos polysaccharide.
Cyclovirobuxinum D alleviates cardiac hypertrophy in hyperthyroid rats by preventing apoptosis of cardiac cells and inhibiting the p38 mitogen-activated protein kinase signaling pathway.
Protection mechanism of Se-containing protein hydrolysates from Se-enriched rice on Pb(2+)-induced apoptosis in PC12 and RAW264.7 cells.
Reoxygenation Reverses Hypoxic Pulmonary Arterial Remodeling by Inducing Smooth Muscle Cell Apoptosis via Reactive Oxygen Species-Mediated Mitochondrial Dysfunction.
Silencing of astrocyte elevated gene-1 inhibits proliferation and migration of melanoma cells and induces apoptosis.
In vivo inhibitory activity of andrographolide derivative ADN-9 against liver cancer and its mechanisms involved in inhibition of tumor angiogenesis.
Nephroprotective Effects of Saponins from Leaves of Panax quinquefolius against Cisplatin-Induced Acute Kidney Injury.
Study on antitumor, antioxidant and immunoregulatory activities of the purified polyphenols from pinecone of Pinus koraiensis on tumor-bearing S180 mice in vivo.
Inhibition of cerebral ischemia/reperfusion injury-induced apoptosis: nicotiflorin and JAK2/STAT3 pathway.
4-Methylcatechol inhibits cell growth and testosterone production in TM3 Leydig cells by reducing mitochondrial activity.
Osthole prevents cerebral ischemia-reperfusion injury via the Notch signaling pathway.
Glycyrrhizic Acid Attenuates Sepsis-Induced Acute Kidney Injury by Inhibiting NF-κB Signaling Pathway.
miR-21 Reduces Hydrogen Peroxide-Induced Apoptosis in c-kit(+) Cardiac Stem Cells In Vitro through PTEN/PI3K/Akt Signaling.
A Novel Microspheres Formulation of Puerarin: Pharmacokinetics Study and In Vivo Pharmacodynamics Evaluations.
Valproate Attenuates Nitroglycerin-Induced Trigeminovascular Activation by Preserving Mitochondrial Function in a Rat Model of Migraine.
The natural secolignan peperomin E induces apoptosis of human gastric carcinoma cells via the mitochondrial and PI3K/Akt signaling pathways in vitro and in vivo.
Glycyrrhizic Acid Prevents Sepsis-Induced Acute Lung Injury and Mortality in Rats.
Curcumin alleviates glucocorticoid-induced osteoporosis by protecting osteoblasts from apoptosis in vivo and in vitro.
Radix Ilicis Pubescentis total flavonoids combined with mobilization of bone marrow stem cells to protect against cerebral ischemia/reperfusion injury.
Effect of quercetin on the expression of Bcl-2/Bax apoptotic proteins in endometrial cells of lipopolysaccharide-induced-abortion.
Ginkgo biloba leaf extract and alpha-tocopherol attenuate haloperidol-induced orofacial dyskinesia in rats: Possible implication of antiapoptotic mechanisms by preventing Bcl-2 decrease and Bax elevation.
Xuezhikang () reduced renal cell apoptosis in streptozocin-induced diabetic rats through regulation of Bcl-2 family.
Effect of curcumin on Bcl-2 and Bax expression in nude mice prostate cancer.
Effects of intracerebral hemorrhage and subsequent minimally invasive hematoma aspiration on expression of apoptosisrelated genes in rats.
Effects of PDTC on NF-κB expression and apoptosis in rats with severe acute pancreatitis-associated lung injury.
Alpha-lipoic acid attenuates trinitrobenzene sulfonic acid-induced ulcerative colitis in mice.
Expression of TP53, BCL-2, and VEGFA Genes in Esophagus Carcinoma and its Biological Significance.
The effects of acupuncture and traditional Chinese medicines on apoptosis of brain tissue in a rat intracerebral hemorrhage model.
Design of magnetic nanoparticles for hepatocellular carcinoma treatment using the control mechanisms of the cell internal nucleus and external membrane.
Cycloartan-24-ene-1α,2α,3β-triol, a cycloartane-type triterpenoid from the resinous exudates of Commiphora myrrha, induces apoptosis in human prostatic cancer PC-3 cells.
Cooperative effect of Bifidobacteria lipoteichoic acid combined with 5-fluorouracil on hepatoma-22 cells growth and apoptosis.
Inhibitory effect of tetramethylpyrazine preconditioning on overload training-induced myocardial apoptosis in rats.
Protective Effects of Baicalin on Aβ₁₋₄₂-Induced Learning and Memory Deficit, Oxidative Stress, and Apoptosis in Rat.
Forsythiaside protects against hydrogen peroxide-induced oxidative stress and apoptosis in PC12 cell.
Interleukin-6 enhances acid-induced apoptosis via upregulating acid-sensing ion channel 1a expression and function in rat articular chondrocytes.
Pathway of programmed cell death and oxidative stress induced by β-hydroxybutyrate in dairy cow abomasum smooth muscle cells and in mouse gastric smooth muscle.
The viral oncoprotein HBx of Hepatitis B virus promotes the growth of hepatocellular carcinoma through cooperating with the cellular oncoprotein RMP.
Protective effects of phillyrin on H2O 2-induced oxidative stress and apoptosis in PC12 cells.
Colistin-induced apoptosis in PC12 cells: involvement of the mitochondrial apoptotic and death receptor pathways.
Intervention effects of QRZSLXF, a Chinese medicinal herb recipe, on the DOR-β-arrestin1-Bcl2 signal transduction pathway in a rat model of ulcerative colitis.
Effect of ligustilide on Ang II-induced hypertrophy in cardiomyocytes and the potential mechanisms.
Protective effects of total flavonoids from Epimedium on the male mouse reproductive system against cyclophosphamide-induced oxidative injury by up-regulating the expressions of SOD3 and GPX1.
Acupuncture at Baihui and Dazhui reduces brain cell apoptosis in heroin readdicts.
Glutamate microinjection into the hypothalamic paraventricular nucleus attenuates ulcerative colitis in rats.
Role of DOR-β-arrestin1-Bcl2 signal transduction pathway and intervention effects of oxymatrine in ulcerative colitis.
Mitochondrial- and Fas-L-mediated pathways involved in quinestrol induced spermatogenic apoptosis in adult rat testes.
Cyclosporine a inhibits apoptosis of rat gingival epithelium.
Intracranial injection of recombinant stromal-derived factor-1 alpha (SDF-1α) attenuates traumatic brain injury in rats.
Effect and mechanism of propofol on myocardial ischemia reperfusion injury in type 2 diabetic rats.
The Effects of Fasudil at Different Doses on Acute Myocardial Infarction in Rats.
Molecular mechanism of inhibitory effects of CD59 gene on atherosclerosis in ApoE (-/-) mice.
Bone morphogenetic protein-7 (BMP-7) mediates ischemic preconditioning-induced ischemic tolerance via attenuating apoptosis in rat brain.
Effects of fluoride on liver apoptosis and Bcl-2, Bax protein expression in freshwater teleost, Cyprinus carpio.
Characterization of side population cells isolated from the gastric cancer cell line SGC-7901.
Hepatosteatosis and hepatic insulin resistance are blunted by argirein, an anti-inflammatory agent, through normalizing endoplasmic reticulum stress and apoptosis in diabetic liver.
Delivery of the co-expression plasmid pEndo-Si-Stat3 by attenuated Salmonella serovar typhimurium for prostate cancer treatment.
Combined early fluid resuscitation and hydrogen inhalation attenuates lung and intestine injury.
8-hydroxy-2-(di-n-propylamino)tetralin intervenes with neural cell apoptosis following diffuse axonal injury.
Protective effects of ginseng total saponins against hepatic ischemia/reperfusion injury in experimental obstructive jaundice rats.
Expressions of apoptosis-related proteins in rats with focal cerebral ischemia after Angong Niuhuang sticker point application.
Protective effect of Danhong injection on cerebral ischemia-reperfusion injury in rats.
Synergistic protective effect of astragaloside IV-tetramethylpyrazine against cerebral ischemic-reperfusion injury induced by transient focal ischemia.
Erythromycin ameliorates cigarette-smoke-induced emphysema and inflammation in rats.
Neuroprotective effects of tanshinone IIA and/or tetramethylpyrazine in cerebral ischemic injury in vivo and in vitro.
Picroside II protects cardiomyocytes from hypoxia/reoxygenation-induced apoptosis by activating the PI3K/Akt and CREB pathways.
Erythropoietin protects pancreatic β-cell line NIT-1 cells against cytokine-induced apoptosis via phosphatidylinositol 3-kinase/Akt signaling.
Roux-en-Y gastric bypass-induced improvement of glucose tolerance and insulin resistance in type 2 diabetic rats are mediated by glucagon-like peptide-1.
Interfering effect and mechanism of neuregulin on experimental dementia model in rats.
Protective effects of Carthamus tinctorius injection on isoprenaline-induced myocardial injury in rats.
Elevated expression of Dickkopf-1 increases the sensitivity of human glioma cell line SHG44 to BCNU.
Myocardial apoptosis and infarction after ischemia/reperfusion are attenuated by kappa-opioid receptor agonist.
In vitro and in vivo antitumor effects of acetylshikonin isolated from Arnebia euchroma (Royle) Johnst (Ruanzicao) cell suspension cultures.
Protective effects and mechanism of puerarin on learning-memory disorder after global cerebral ischemia-reperfusion injury in rats.
Immunoregulatory and anti-tumor effects of polysaccharopeptide and Astragalus polysaccharides on tumor-bearing mice.
Protective effects of naringenin-7-O-glucoside on doxorubicin-induced apoptosis in H9C2 cells.
The effect of targeted magnetic nanopaticles on hepatoma and the expression of bcl-2/bax protein.
Neuroprotective effects of tetramethylpyrazine on hydrogen peroxide-induced apoptosis in PC12 cells.
Comparison of rapamycin versus FK506 on expression of cytoprotective genes in the rat kidney allografts undergoing chronic allograft nephropathy.
Conversion from cyclosporine to mycophenolate mofetil improves expression of A20 in the rat kidney allografts undergoing chronic rejection.
Molecular immune mechanism of C-phycocyanin from Spirulina platensis induces apoptosis in HeLa cells in vitro.
Immunomodulatory and antitumour effects of an exopolysaccharide fraction from cultivated Cordyceps sinensis (Chinese caterpillar fungus) on tumour-bearing mice.
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Adiponectin attenuates H2O2-induced apoptosis in chicken skeletal myoblasts through the lysosomal-mitochondrial axis.
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The combined analgesic, sedative, and anti-gastric cancer mechanisms of Tinospora sagittata var. yunnanensis (S. Y. Hu) H. S. Lo based on integrated ethnopharmacological data.
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Modified CFBP-bFGF targeting to ischemic brain promoted the functional recovery of cerebral ischemia.
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Rutaecarpine Ameliorates Murine N-Methyl-N'-Nitro-N-Nitrosoguanidine-Induced Chronic Atrophic Gastritis by Sonic Hedgehog Pathway.
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lncRNA HOTTIP Recruits EZH2 to Inhibit PTEN Expression and Participates in IM Resistance in Chronic Myeloid Leukemia.
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Soluble Epoxide Hydrolase Inhibition Protected against Diabetic Cardiomyopathy through Inducing Autophagy and Reducing Apoptosis Relying on Nrf2 Upregulation and Transcription Activation.
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MiR-153 downregulation alleviates PTSD-like behaviors and reduces cell apoptosis by upregulating the Sigma-1 receptor in the hippocampus of rats exposed to single-prolonged stress.
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Mechanism of Action of Xiaoyao San in Treatment of Ischemic Stroke is Related to Anti-Apoptosis and Activation of PI3K/Akt Pathway.
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SIRT1/PGC-1α signaling activation by mangiferin attenuates cerebral hypoxia/reoxygenation injury in neuroblastoma cells.
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Continuous artificial light at night exacerbates diisononyl phthalate-induced learning and memory impairment in mice: Toxicological evidence.
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Insulin injections inhibits PTZ-induced mitochondrial dysfunction, oxidative stress and neurological deficits via the SIRT1/PGC-1α/SIRT3 pathway.
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Protective Effect of GM1 Attenuates Hippocampus and Cortex Apoptosis After Ketamine Exposure in Neonatal Rat via PI3K/AKT/GSK3β Pathway.
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Molecular neurobiology 2021 Jul;58(7):3471-3483
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TRB3 mediates vascular remodeling by activating the MAPK signaling pathway in hypoxic pulmonary hypertension.
Cao X, Fang X, Guo M, Li X, He Y, Xie M, Xu Y, Liu X
Respiratory research 2021 Dec 14;22(1):312
Respiratory research 2021 Dec 14;22(1):312
CircHIPK3 regulates the autophagy and apoptosis of hypoxia/reoxygenation-stimulated cardiomyocytes via the miR-20b-5p/ATG7 axis.
Qiu Z, Wang Y, Liu W, Li C, Zhao R, Long X, Rong J, Deng W, Shen C, Yuan J, Chen W, Shi B
Cell death discovery 2021 Apr 6;7(1):64
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Hydroxy-α-sanshool Possesses Protective Potentials on H(2)O(2)-Stimulated PC12 Cells by Suppression of Oxidative Stress-Induced Apoptosis through Regulation of PI3K/Akt Signal Pathway.
Li RL, Zhang Q, Liu J, Sun JY, He LY, Duan HX, Peng W, Wu CJ
Oxidative medicine and cellular longevity 2020;2020:3481758
Oxidative medicine and cellular longevity 2020;2020:3481758
CircPOSTN/miR-361-5p/TPX2 axis regulates cell growth, apoptosis and aerobic glycolysis in glioma cells.
Long N, Chu L, Jia J, Peng S, Gao Y, Yang H, Yang Y, Zhao Y, Liu J
Cancer cell international 2020;20:374
Cancer cell international 2020;20:374
Schizandrol A protects against Aβ(1-42)-induced autophagy via activation of PI3K/AKT/mTOR pathway in SH-SY5Y cells and primary hippocampal neurons.
Song L, Yao L, Zhang L, Piao Z, Lu Y
Naunyn-Schmiedeberg's archives of pharmacology 2020 Sep;393(9):1739-1752
Naunyn-Schmiedeberg's archives of pharmacology 2020 Sep;393(9):1739-1752
COX-2-PGE(2) signaling pathway contributes to hippocampal neuronal injury and cognitive impairment in PTZ-kindled epilepsy mice.
Zhu X, Yao Y, Yang J, Zhengxie J, Li X, Hu S, Zhang A, Dong J, Zhang C, Gan G
International immunopharmacology 2020 Oct;87:106801
International immunopharmacology 2020 Oct;87:106801
Aptamer-protamine-siRNA nanoparticles in targeted therapy of ErbB3 positive breast cancer cells.
Xu X, Li L, Li X, Tao D, Zhang P, Gong J
International journal of pharmaceutics 2020 Nov 30;590:119963
International journal of pharmaceutics 2020 Nov 30;590:119963
Antihypertensive and renal protective effect of Shunaoxin pill combined with captopril on spontaneous hypertension rats.
Man S, Yang L, Xiang H, Lu G, Wang Y, Liu C, Gao W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109977
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109977
The PI3K/Akt and NF-κB signaling pathways are involved in the protective effects of Lithocarpus polystachyus (sweet tea) on APAP-induced oxidative stress injury in mice.
Yang JY, Zhong YT, Hao WN, Liu XX, Shen Q, Li YF, Ren S, Wang Z, Li W, Zhao LC
RSC advances 2020 May 10;10(31):18044-18053
RSC advances 2020 May 10;10(31):18044-18053
Neuroprotective effects of miR-532-5p against ischemic stroke.
Mu J, Cheng X, Zhong S, Chen X, Zhao C
Metabolic brain disease 2020 Jun;35(5):753-763
Metabolic brain disease 2020 Jun;35(5):753-763
Lactobacillus rhamnosus FLRH93 protects against intestinal damage in mice induced by 5-fluorouracil.
Hu M, Wu X, Luo M, Wei H, Xu D, Xu F
Journal of dairy science 2020 Jun;103(6):5003-5018
Journal of dairy science 2020 Jun;103(6):5003-5018
Icariin improves cognitive deficits by reducing the deposition of β-amyloid peptide and inhibition of neurons apoptosis in SAMP8 mice.
Wu J, Qu JQ, Zhou YJ, Zhou YJ, Li YY, Huang NQ, Deng CM, Luo Y
Neuroreport 2020 Jun 7;31(9):663-671
Neuroreport 2020 Jun 7;31(9):663-671
Antioxidant preconditioning improves therapeutic outcomes of adipose tissue-derived mesenchymal stem cells through enhancing intrahepatic engraftment efficiency in a mouse liver fibrosis model.
Liao N, Shi Y, Wang Y, Liao F, Zhao B, Zheng Y, Zeng Y, Liu X, Liu J
Stem cell research & therapy 2020 Jun 16;11(1):237
Stem cell research & therapy 2020 Jun 16;11(1):237
Crocin protects against cardiotoxicity induced by doxorubicin through TLR-2/NF-κB signal pathway in vivo and vitro.
Chu X, Zhang Y, Xue Y, Li Z, Shi J, Wang H, Chu L
International immunopharmacology 2020 Jul;84:106548
International immunopharmacology 2020 Jul;84:106548
[6]-Gingerol Ameliorates ISO-Induced Myocardial Fibrosis by Reducing Oxidative Stress, Inflammation, and Apoptosis through Inhibition of TLR4/MAPKs/NF-κB Pathway.
Han X, Liu P, Liu M, Wei Z, Fan S, Wang X, Sun S, Chu L
Molecular nutrition & food research 2020 Jul;64(13):e2000003
Molecular nutrition & food research 2020 Jul;64(13):e2000003
The study of effect and mechanism of 630-nm laser on human lung adenocarcinoma cell xenograft model in nude mice mediated by hematoporphyrin derivatives.
Lin C, Zhang Y, Wang J, Sui A, Xiu L, Zhu X
Lasers in medical science 2020 Jul;35(5):1085-1094
Lasers in medical science 2020 Jul;35(5):1085-1094
MiR-183-5p protects rat hearts against myocardial ischemia/reperfusion injury through targeting VDAC1.
Lin D, Cui B, Ma J, Ren J
BioFactors (Oxford, England) 2020 Jan;46(1):83-93
BioFactors (Oxford, England) 2020 Jan;46(1):83-93
MicroRNA-375 exacerbates knee osteoarthritis through repressing chondrocyte autophagy by targeting ATG2B.
Li H, Li Z, Pi Y, Chen Y, Mei L, Luo Y, Xie J, Mao X
Aging 2020 Apr 26;12(8):7248-7261
Aging 2020 Apr 26;12(8):7248-7261
Alteronol Enhances the Anti-tumor Activity and Reduces the Toxicity of High-Dose Adriamycin in Breast Cancer.
Ren B, Ye L, Gong J, Ren H, Ding Y, Chen X, Liu X, Lu P, Wei F, Xu W, Zheng Q, Li D
Frontiers in pharmacology 2019;10:285
Frontiers in pharmacology 2019;10:285
Trimetazidine Attenuates Exhaustive Exercise-Induced Myocardial Injury in Rats via Regulation of the Nrf2/NF-κB Signaling Pathway.
Zhang H, Liu M, Zhang Y, Li X
Frontiers in pharmacology 2019;10:175
Frontiers in pharmacology 2019;10:175
Elimination of Intracellular Calcium Overload by BAPTA-AM-Loaded Liposomes: A Promising Therapeutic Agent for Acute Liver Failure.
Fu Z, Fan Q, Zhou Y, Zhao Y, He Z
ACS applied materials & interfaces 2019 Oct 30;11(43):39574-39585
ACS applied materials & interfaces 2019 Oct 30;11(43):39574-39585
Effects of rosmarinic acid on immunoregulatory activity and hepatocellular carcinoma cell apoptosis in H22 tumor-bearing mice.
Cao W, Mo K, Wei S, Lan X, Zhang W, Jiang W
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2019 Nov;23(6):501-508
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2019 Nov;23(6):501-508
Preoperative vitamin-rich carbohydrate loading alleviates postoperative cognitive dysfunction in aged rats.
Zuo Y, Hu X, Yang Q, Zhao L, Chen X, Lin J, Yang T
Behavioural brain research 2019 Nov 5;373:112107
Behavioural brain research 2019 Nov 5;373:112107
Noncoding transcribed ultraconserved region (T-UCR) UC.48+ is a novel regulator of high-fat diet induced myocardial ischemia/reperfusion injury.
Ding L, Gong C, Zhao J, Liu X, Li T, Rao S, Wang S, Liu Y, Peng S, Xiao W, Xiong C, Wang R, Liang S, Xu H
Journal of cellular physiology 2019 Jun;234(6):9849-9861
Journal of cellular physiology 2019 Jun;234(6):9849-9861
Inotodiol inhibits cells migration and invasion and induces apoptosis via p53-dependent pathway in HeLa cells.
Zhang SD, Yu L, Wang P, Kou P, Li J, Wang LT, Wang W, Yao LP, Zhao XH, Fu YJ
Phytomedicine : international journal of phytotherapy and phytopharmacology 2019 Jul;60:152957
Phytomedicine : international journal of phytotherapy and phytopharmacology 2019 Jul;60:152957
LaSota Strain Expressing The Rabies Virus Glycoprotein (rL-RVG) Suppresses Gastric Cancer by Inhibiting the Alpha 7 Nicotinic Acetylcholine Receptor (α7 nAChR)/Phosphoinositide 3-Kinase (PI3K)/AKT Pathway.
Bu X, Yin C, Zhang X, Zhang A, Shao X, Zhang Y, Yan Y
Medical science monitor : international medical journal of experimental and clinical research 2019 Jul 24;25:5482-5492
Medical science monitor : international medical journal of experimental and clinical research 2019 Jul 24;25:5482-5492
MiR-199a-5p regulates rat liver regeneration and hepatocyte proliferation by targeting TNF-α TNFR1/TRADD/CASPASE8/CASPASE3 signalling pathway.
Zhang C, Ye B, Wei J, Wang Q, Xu C, Yu G
Artificial cells, nanomedicine, and biotechnology 2019 Dec;47(1):4110-4118
Artificial cells, nanomedicine, and biotechnology 2019 Dec;47(1):4110-4118
Protective effects of pentadecapeptide derived from Cyclaina sinensis against cyclophosphamide-induced hepatotoxicity.
Jiang X, Yang F, Zhao Q, Tian D, Tang Y
Biochemical and biophysical research communications 2019 Dec 3;520(2):392-398
Biochemical and biophysical research communications 2019 Dec 3;520(2):392-398
Treatment with MQA, a Derivative of Caffeoylquinic Acid, Provides Neuroprotective Effects against Cerebral Ischemia Through Suppression of the p38 Pathway and Oxidative Stress in Rats.
Chen L, Liu DN, Wang Y, Liu XY, Han S, Zhang K, Li GY, Tian X, Wang HY, Wang JH
Journal of molecular neuroscience : MN 2019 Apr;67(4):604-612
Journal of molecular neuroscience : MN 2019 Apr;67(4):604-612
Exosomes Derived from miR-214-Enriched Bone Marrow-Derived Mesenchymal Stem Cells Regulate Oxidative Damage in Cardiac Stem Cells by Targeting CaMKII.
Wang Y, Zhao R, Liu D, Deng W, Xu G, Liu W, Rong J, Long X, Ge J, Shi B
Oxidative medicine and cellular longevity 2018;2018:4971261
Oxidative medicine and cellular longevity 2018;2018:4971261
Neural Stem Cell-Conditioned Medium Ameliorated Cerebral Ischemia-Reperfusion Injury in Rats.
Yang H, Wang C, Chen H, Li L, Ma S, Wang H, Fu Y, Qu T
Stem cells international 2018;2018:4659159
Stem cells international 2018;2018:4659159
Perfluorooctanoic acid exposure during pregnancy alters the apoptosis of uterine cells in pregnant mice.
Li D, Song P, Liu L, Wang X
International journal of clinical and experimental pathology 2018;11(12):5602-5611
International journal of clinical and experimental pathology 2018;11(12):5602-5611
RRM2 promotes the progression of human glioblastoma.
Li C, Zheng J, Chen S, Huang B, Li G, Feng Z, Wang J, Xu S
Journal of cellular physiology 2018 Oct;233(10):6759-6767
Journal of cellular physiology 2018 Oct;233(10):6759-6767
The protective effects of maltol on cisplatin-induced nephrotoxicity through the AMPK-mediated PI3K/Akt and p53 signaling pathways.
Mi XJ, Hou JG, Wang Z, Han Y, Ren S, Hu JN, Chen C, Li W
Scientific reports 2018 Oct 29;8(1):15922
Scientific reports 2018 Oct 29;8(1):15922
Insight into the negative impact of ionic liquid: A cytotoxicity mechanism of 1-methyl-3-octylimidazolium bromide.
Ma J, Li X
Environmental pollution (Barking, Essex : 1987) 2018 Nov;242(Pt B):1337-1345
Environmental pollution (Barking, Essex : 1987) 2018 Nov;242(Pt B):1337-1345
Platycodin D protects acetaminophen-induced hepatotoxicity by inhibiting hepatocyte MAPK pathway and apoptosis in C57BL/6J mice.
Fu CL, Liu Y, Leng J, Zhang J, He YF, Chen C, Wang Z, Li W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Nov;107:867-877
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Nov;107:867-877
Role of capsaicin sensitive sensory nerves in ischemia reperfusion-induced acute kidney injury in rats.
Zhang S, Liu H, Xu Q, Huang F, Xu R, Liu Q, Lv Y
Biochemical and biophysical research communications 2018 Nov 17;506(1):176-182
Biochemical and biophysical research communications 2018 Nov 17;506(1):176-182
Adolescent cocaine exposure induces prolonged synaptic modifications in medial prefrontal cortex of adult rats.
Zhu W, Ge X, Gao P, Li M, Guan Y, Guan X
Brain structure & function 2018 May;223(4):1829-1838
Brain structure & function 2018 May;223(4):1829-1838
Improvement of Cisplatin-induced renal dysfunction by Schisandra chinensis stems via anti-inflammation and anti-apoptosis effects.
Li YZ, Ren S, Yan XT, Li HP, Li W, Zheng B, Wang Z, Liu YY
Journal of ethnopharmacology 2018 May 10;217:228-237
Journal of ethnopharmacology 2018 May 10;217:228-237
Neuroprotective effects of a triple GLP-1/GIP/glucagon receptor agonist in the APP/PS1 transgenic mouse model of Alzheimer's disease.
Tai J, Liu W, Li Y, Li L, Hölscher C
Brain research 2018 Jan 1;1678:64-74
Brain research 2018 Jan 1;1678:64-74
Protective effects of a Ganoderma atrum polysaccharide against acrylamide induced oxidative damage via a mitochondria mediated intrinsic apoptotic pathway in IEC-6 cells.
Jiang G, Zhang L, Wang H, Chen Q, Wu X, Yan X, Chen Y, Xie M
Food & function 2018 Feb 21;9(2):1133-1143
Food & function 2018 Feb 21;9(2):1133-1143
Ectopic expression of Miro 1 ameliorates seizures and inhibits hippocampal neurodegeneration in a mouse model of pilocarpine epilepsy.
Zhang H, Lian Y, Xie N, Zheng Y
Biochemistry and cell biology = Biochimie et biologie cellulaire 2018 Aug;96(4):468-474
Biochemistry and cell biology = Biochimie et biologie cellulaire 2018 Aug;96(4):468-474
Canonical Transient Receptor Potential Channel 3 Contributes to Febrile Seizure Inducing Neuronal Cell Death and Neuroinflammation.
Sun D, Ma H, Ma J, Wang J, Deng X, Hu C, Deng X
Cellular and molecular neurobiology 2018 Aug;38(6):1215-1226
Cellular and molecular neurobiology 2018 Aug;38(6):1215-1226
The impact of acute thermal stress on green mussel Perna viridis: Oxidative damage and responses.
Wang J, Dong B, Yu ZX, Yao CL
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 2018 Aug;222:7-15
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 2018 Aug;222:7-15
Lithium chloride (LiCl) induced autophagy and downregulated expression of transforming growth factor β-induced protein (TGFBI) in granular corneal dystrophy.
Nie D, Peng Y, Li M, Liu X, Zhu M, Ye L
Experimental eye research 2018 Aug;173:44-50
Experimental eye research 2018 Aug;173:44-50
PSMB8 regulates glioma cell migration, proliferation, and apoptosis through modulating ERK1/2 and PI3K/AKT signaling pathways.
Yang BY, Song JW, Sun HZ, Xing JC, Yang ZH, Wei CY, Xu TY, Yu ZN, Zhang YN, Wang YF, Chang H, Xu ZP, Hou M, Ji MJ, Zhang YS
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Apr;100:205-212
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Apr;100:205-212
Acute downregulation of miR-199a attenuates sepsis-induced acute lung injury by targeting SIRT1.
Liu Y, Guan H, Zhang JL, Zheng Z, Wang HT, Tao K, Han SC, Su LL, Hu D
American journal of physiology. Cell physiology 2018 Apr 1;314(4):C449-C455
American journal of physiology. Cell physiology 2018 Apr 1;314(4):C449-C455
Inhibition of glioblastoma growth and invasion by (125)I brachytherapy in rat glioma model.
Chen F, Wang D
American journal of translational research 2017;9(5):2243-2254
American journal of translational research 2017;9(5):2243-2254
Lipoxin A4 pretreatment mitigates skeletal muscle ischemia-reperfusion injury in rats.
Zong H, Li X, Lin H, Hou C, Ma F
American journal of translational research 2017;9(3):1139-1150
American journal of translational research 2017;9(3):1139-1150
Protective Effects of Sodium (±)-5-Bromo-2-(α-Hydroxypentyl) Benzoate in a Rodent Model of Global Cerebral Ischemia.
Gao Y, Li M, Wang Y, Li Z, Fan C, Wang Z, Cao X, Chang J, Qiao H
Frontiers in pharmacology 2017;8:691
Frontiers in pharmacology 2017;8:691
Celastrol Attenuates Multiple Sclerosis and Optic Neuritis in an Experimental Autoimmune Encephalomyelitis Model.
Yang H, Liu C, Jiang J, Wang Y, Zhang X
Frontiers in pharmacology 2017;8:44
Frontiers in pharmacology 2017;8:44
MicroRNA-210 alleviates oxidative stress-associated cardiomyocyte apoptosis by regulating BNIP3.
Diao H, Liu B, Shi Y, Song C, Guo Z, Liu N, Song X, Lu Y, Lin X, Li Z
Bioscience, biotechnology, and biochemistry 2017 Sep;81(9):1712-1720
Bioscience, biotechnology, and biochemistry 2017 Sep;81(9):1712-1720
Antitumorpharmacological mechanism of the oral liquid of Poriacocos polysaccharide.
Shi C, Ma Q, Ren M, Liang D, Yu Q, Luo J
Journal of ethnopharmacology 2017 Sep 14;209:24-31
Journal of ethnopharmacology 2017 Sep 14;209:24-31
Cyclovirobuxinum D alleviates cardiac hypertrophy in hyperthyroid rats by preventing apoptosis of cardiac cells and inhibiting the p38 mitogen-activated protein kinase signaling pathway.
Wu JB, Zhou Y, Liang CL, Zhang XJ, Lai JM, Ye SF, Ouyang H, Lin J, Zhou JY
Chinese journal of integrative medicine 2017 Oct;23(10):770-778
Chinese journal of integrative medicine 2017 Oct;23(10):770-778
Protection mechanism of Se-containing protein hydrolysates from Se-enriched rice on Pb(2+)-induced apoptosis in PC12 and RAW264.7 cells.
Fang Y, Xu Z, Shi Y, Pei F, Yang W, Ma N, Kimatu BM, Liu K, Qiu W, Hu Q
Food chemistry 2017 Mar 15;219:391-398
Food chemistry 2017 Mar 15;219:391-398
Reoxygenation Reverses Hypoxic Pulmonary Arterial Remodeling by Inducing Smooth Muscle Cell Apoptosis via Reactive Oxygen Species-Mediated Mitochondrial Dysfunction.
Chen J, Wang YX, Dong MQ, Zhang B, Luo Y, Niu W, Li ZC
Journal of the American Heart Association 2017 Jun 23;6(6)
Journal of the American Heart Association 2017 Jun 23;6(6)
Silencing of astrocyte elevated gene-1 inhibits proliferation and migration of melanoma cells and induces apoptosis.
Zhang Y, Peng G, Wang Y, Cui L, Wu W, Wang L, Liu C, Han X
Clinical and experimental pharmacology & physiology 2017 Jul;44(7):815-826
Clinical and experimental pharmacology & physiology 2017 Jul;44(7):815-826
In vivo inhibitory activity of andrographolide derivative ADN-9 against liver cancer and its mechanisms involved in inhibition of tumor angiogenesis.
Yang W, Zhao J, Wang Y, Xu H, Wu Z, Hu Y, Jiang K, Shen P, Ma C, Guan Z, Zhang Y, Ma J, Shang N, Yan G, Wang Z, Dai G
Toxicology and applied pharmacology 2017 Jul 15;327:1-12
Toxicology and applied pharmacology 2017 Jul 15;327:1-12
Nephroprotective Effects of Saponins from Leaves of Panax quinquefolius against Cisplatin-Induced Acute Kidney Injury.
Ma ZN, Li YZ, Li W, Yan XT, Yang G, Zhang J, Zhao LC, Yang LM
International journal of molecular sciences 2017 Jul 13;18(7)
International journal of molecular sciences 2017 Jul 13;18(7)
Study on antitumor, antioxidant and immunoregulatory activities of the purified polyphenols from pinecone of Pinus koraiensis on tumor-bearing S180 mice in vivo.
Yi J, Qu H, Wu Y, Wang Z, Wang L
International journal of biological macromolecules 2017 Jan;94(Pt A):735-744
International journal of biological macromolecules 2017 Jan;94(Pt A):735-744
Inhibition of cerebral ischemia/reperfusion injury-induced apoptosis: nicotiflorin and JAK2/STAT3 pathway.
Hu GQ, Du X, Li YJ, Gao XQ, Chen BQ, Yu L
Neural regeneration research 2017 Jan;12(1):96-102
Neural regeneration research 2017 Jan;12(1):96-102
4-Methylcatechol inhibits cell growth and testosterone production in TM3 Leydig cells by reducing mitochondrial activity.
Li CJ, Jiang YW, Chen SX, Li HJ, Chen L, Liu YT, Gao S, Zhao Y, Zhu XL, Wang HT, Wang FG, Zheng L, Zhou X
Andrologia 2017 Feb;49(1)
Andrologia 2017 Feb;49(1)
Osthole prevents cerebral ischemia-reperfusion injury via the Notch signaling pathway.
Guan J, Wei X, Qu S, Lv T, Fu Q, Yuan Y
Biochemistry and cell biology = Biochimie et biologie cellulaire 2017 Aug;95(4):459-467
Biochemistry and cell biology = Biochimie et biologie cellulaire 2017 Aug;95(4):459-467
Glycyrrhizic Acid Attenuates Sepsis-Induced Acute Kidney Injury by Inhibiting NF-κB Signaling Pathway.
Zhao H, Zhao M, Wang Y, Li F, Zhang Z
Evidence-based complementary and alternative medicine : eCAM 2016;2016:8219287
Evidence-based complementary and alternative medicine : eCAM 2016;2016:8219287
miR-21 Reduces Hydrogen Peroxide-Induced Apoptosis in c-kit(+) Cardiac Stem Cells In Vitro through PTEN/PI3K/Akt Signaling.
Deng W, Wang Y, Long X, Zhao R, Wang Z, Liu Z, Cao S, Shi B
Oxidative medicine and cellular longevity 2016;2016:5389181
Oxidative medicine and cellular longevity 2016;2016:5389181
A Novel Microspheres Formulation of Puerarin: Pharmacokinetics Study and In Vivo Pharmacodynamics Evaluations.
Song X, Bai X, Liu S, Dong L, Deng H, Wang C
Evidence-based complementary and alternative medicine : eCAM 2016;2016:4016963
Evidence-based complementary and alternative medicine : eCAM 2016;2016:4016963
Valproate Attenuates Nitroglycerin-Induced Trigeminovascular Activation by Preserving Mitochondrial Function in a Rat Model of Migraine.
Li R, Liu Y, Chen N, Zhang Y, Song G, Zhang Z
Medical science monitor : international medical journal of experimental and clinical research 2016 Sep 12;22:3229-37
Medical science monitor : international medical journal of experimental and clinical research 2016 Sep 12;22:3229-37
The natural secolignan peperomin E induces apoptosis of human gastric carcinoma cells via the mitochondrial and PI3K/Akt signaling pathways in vitro and in vivo.
Wang XZ, Cheng Y, Wu H, Li N, Liu R, Yang XL, Qiu YY, Wen HM, Liang JY
Phytomedicine : international journal of phytotherapy and phytopharmacology 2016 Jul 15;23(8):818-27
Phytomedicine : international journal of phytotherapy and phytopharmacology 2016 Jul 15;23(8):818-27
Glycyrrhizic Acid Prevents Sepsis-Induced Acute Lung Injury and Mortality in Rats.
Zhao H, Zhao M, Wang Y, Li F, Zhang Z
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2016 Feb;64(2):125-37
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2016 Feb;64(2):125-37
Curcumin alleviates glucocorticoid-induced osteoporosis by protecting osteoblasts from apoptosis in vivo and in vitro.
Chen Z, Xue J, Shen T, Ba G, Yu D, Fu Q
Clinical and experimental pharmacology & physiology 2016 Feb;43(2):268-76
Clinical and experimental pharmacology & physiology 2016 Feb;43(2):268-76
Radix Ilicis Pubescentis total flavonoids combined with mobilization of bone marrow stem cells to protect against cerebral ischemia/reperfusion injury.
Miao MS, Guo L, Li RQ, Ma X
Neural regeneration research 2016 Feb;11(2):278-84
Neural regeneration research 2016 Feb;11(2):278-84
Effect of quercetin on the expression of Bcl-2/Bax apoptotic proteins in endometrial cells of lipopolysaccharide-induced-abortion.
Wang X, Yan Y, Yang L, Li M, Zhong X
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2016 Dec;36(6):737-42
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2016 Dec;36(6):737-42
Ginkgo biloba leaf extract and alpha-tocopherol attenuate haloperidol-induced orofacial dyskinesia in rats: Possible implication of antiapoptotic mechanisms by preventing Bcl-2 decrease and Bax elevation.
An HM, Tan YL, Shi J, Wang Z, Lv MH, Soares JC, Zhou D, Yang F, Zhang XY
Phytomedicine : international journal of phytotherapy and phytopharmacology 2016 Dec 1;23(13):1653-1660
Phytomedicine : international journal of phytotherapy and phytopharmacology 2016 Dec 1;23(13):1653-1660
Xuezhikang () reduced renal cell apoptosis in streptozocin-induced diabetic rats through regulation of Bcl-2 family.
Lu WN, Zheng FP, Lai DW, Li H
Chinese journal of integrative medicine 2016 Aug;22(8):611-8
Chinese journal of integrative medicine 2016 Aug;22(8):611-8
Effect of curcumin on Bcl-2 and Bax expression in nude mice prostate cancer.
Yang J, Ning J, Peng L, He D
International journal of clinical and experimental pathology 2015;8(8):9272-8
International journal of clinical and experimental pathology 2015;8(8):9272-8
Effects of intracerebral hemorrhage and subsequent minimally invasive hematoma aspiration on expression of apoptosisrelated genes in rats.
Zhang Q, Tang Q, Li X, Li J, Zhang L, Yan C, Cui Y
International journal of clinical and experimental pathology 2015;8(5):5371-8
International journal of clinical and experimental pathology 2015;8(5):5371-8
Effects of PDTC on NF-κB expression and apoptosis in rats with severe acute pancreatitis-associated lung injury.
Kan S, Zhou H, Jin C, Yang H
International journal of clinical and experimental medicine 2015;8(3):3258-70
International journal of clinical and experimental medicine 2015;8(3):3258-70
Alpha-lipoic acid attenuates trinitrobenzene sulfonic acid-induced ulcerative colitis in mice.
Sun J, Zhang H, Guan L, Zhou H, Sun M
International journal of clinical and experimental medicine 2015;8(1):358-67
International journal of clinical and experimental medicine 2015;8(1):358-67
Expression of TP53, BCL-2, and VEGFA Genes in Esophagus Carcinoma and its Biological Significance.
Wei W, Wang Y, Yu X, Ye L, Jiang Y, Cheng Y
Medical science monitor : international medical journal of experimental and clinical research 2015 Oct 6;21:3016-22
Medical science monitor : international medical journal of experimental and clinical research 2015 Oct 6;21:3016-22
The effects of acupuncture and traditional Chinese medicines on apoptosis of brain tissue in a rat intracerebral hemorrhage model.
Chen JC
Physiology & behavior 2015 Nov 1;151:421-5
Physiology & behavior 2015 Nov 1;151:421-5
Design of magnetic nanoparticles for hepatocellular carcinoma treatment using the control mechanisms of the cell internal nucleus and external membrane.
Zhan X, Guan YQ
Journal of materials chemistry. B 2015 May 28;3(20):4191-4204
Journal of materials chemistry. B 2015 May 28;3(20):4191-4204
Cycloartan-24-ene-1α,2α,3β-triol, a cycloartane-type triterpenoid from the resinous exudates of Commiphora myrrha, induces apoptosis in human prostatic cancer PC-3 cells.
Gao W, Su X, Dong X, Chen Y, Zhou C, Xin P, Yu C, Wei T
Oncology reports 2015 Mar;33(3):1107-14
Oncology reports 2015 Mar;33(3):1107-14
Cooperative effect of Bifidobacteria lipoteichoic acid combined with 5-fluorouracil on hepatoma-22 cells growth and apoptosis.
Guo B, Xie N, Wang Y
Bulletin du cancer 2015 Mar;102(3):204-12
Bulletin du cancer 2015 Mar;102(3):204-12
Inhibitory effect of tetramethylpyrazine preconditioning on overload training-induced myocardial apoptosis in rats.
Yang Y, Li ZH, Liu H, Shi WD, Zhang J
Chinese journal of integrative medicine 2015 Jun;21(6):423-30
Chinese journal of integrative medicine 2015 Jun;21(6):423-30
Protective Effects of Baicalin on Aβ₁₋₄₂-Induced Learning and Memory Deficit, Oxidative Stress, and Apoptosis in Rat.
Ding H, Wang H, Zhao Y, Sun D, Zhai X
Cellular and molecular neurobiology 2015 Jul;35(5):623-32
Cellular and molecular neurobiology 2015 Jul;35(5):623-32
Forsythiaside protects against hydrogen peroxide-induced oxidative stress and apoptosis in PC12 cell.
Huang C, Lin Y, Su H, Ye D
Neurochemical research 2015 Jan;40(1):27-35
Neurochemical research 2015 Jan;40(1):27-35
Interleukin-6 enhances acid-induced apoptosis via upregulating acid-sensing ion channel 1a expression and function in rat articular chondrocytes.
Zhou R, Wu X, Wang Z, Ge J, Chen F
International immunopharmacology 2015 Dec;29(2):748-760
International immunopharmacology 2015 Dec;29(2):748-760
Pathway of programmed cell death and oxidative stress induced by β-hydroxybutyrate in dairy cow abomasum smooth muscle cells and in mouse gastric smooth muscle.
Tian W, Wei T, Li B, Wang Z, Zhang N, Xie G
PloS one 2014;9(5):e96775
PloS one 2014;9(5):e96775
The viral oncoprotein HBx of Hepatitis B virus promotes the growth of hepatocellular carcinoma through cooperating with the cellular oncoprotein RMP.
Wang Q, Xu Y, Zhou W, Zhong L, Wen Z, Yu H, Chen S, Shen J, Chen H, She Q, Jiang J, Miao J, Wei W
International journal of biological sciences 2014;10(10):1181-92
International journal of biological sciences 2014;10(10):1181-92
Protective effects of phillyrin on H2O 2-induced oxidative stress and apoptosis in PC12 cells.
Wei T, Tian W, Yan H, Shao G, Xie G
Cellular and molecular neurobiology 2014 Nov;34(8):1165-73
Cellular and molecular neurobiology 2014 Nov;34(8):1165-73
Colistin-induced apoptosis in PC12 cells: involvement of the mitochondrial apoptotic and death receptor pathways.
Jiang H, Li J, Zhou T, Wang C, Zhang H, Wang H
International journal of molecular medicine 2014 May;33(5):1298-304
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- Main image
- Experimental details
- IHC analysis of Bcl-2 using anti-Bcl-2 antibody (A00040-2). Bcl-2 was detected in paraffin-embedded section of mouse small intestine tissue. Heat mediated antigen retrieval was performed in citrate buffer (pH6, epitope retrieval solution) for 20 mins. The tissue section was blocked with 10% goat serum. The tissue section was then incubated with 1μg/ml rabbit anti-Bcl-2 Antibody (A00040-2) overnight at 4°C. Biotinylated goat anti-rabbit IgG was used as secondary antibody and incubated for 30 minutes at 37°C. The tissue section was developed using Strepavidin-Biotin-Complex (SABC)(Catalog # SA1022) with DAB as the chromogen.
- Additional image
