ABIN362594

antibody from antibodies-online

Targeting: BCL2 Bcl-2, PPP1R50

Western blot (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN362594

Provider

antibodies-online

Product name

anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 54-58) antibody

Antibody type

Polyclonal

Antigen

Peptide sequence around AA 54-58 (G-H-T-P-H) derived from Human BCL-2. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen.

Reactivity

Human

Host

Rabbit

Epitope

AA 54-58

Isotype

IgG

Vial size

100 μL

Concentration

1 mg/mL

Storage

Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

References

Submitted references

Phosphorylation status modulates Bcl-2 function during glucocorticoid-induced apoptosis in T lymphocytes.

Huang ST, Cidlowski JA
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002 Jun;16(8):825-32

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In Celebration of 100 Years of Publication.

The Journal of biological chemistry 2001 Jan 5;276(1):1

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BCL-2 is phosphorylated and inactivated by an ASK1/Jun N-terminal protein kinase pathway normally activated at G(2)/M.

Yamamoto K, Ichijo H, Korsmeyer SJ
Molecular and cellular biology 1999 Dec;19(12):8469-78

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Phosphorylation of Bcl-2 is a marker of M phase events and not a determinant of apoptosis.

Ling YH, Tornos C, Perez-Soler R
The Journal of biological chemistry 1998 Jul 24;273(30):18984-91