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Western blot
ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [13]
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- Product number
- ABIN967312 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-B-Cell CLL/lymphoma 2 (BCL2) antibody
- Antibody type
- Monoclonal
- Antigen
- Human Bcl-2 Recombinant Protein
- Reactivity
- Human
- Isotype
- IgG
- Antibody clone number
- 6C8
- Vial size
- 150 µg
- Concentration
- 0.25 mg/ml
- Storage
- Store both the hamster anti-human Bcl-2 antibody and the Jurkat cell lysate undiluted at -20°C.
Submitted references Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death.
BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heterodimerization with Bax.
Bcl-2 and Bcl-x: regulatory switches for lymphoid death and survival.
Bcl-2 blocks p53-dependent apoptosis.
Latent membrane protein of Epstein-Barr virus induces cellular phenotypes independently of expression of Bcl-2.
Expression of the Bcl-2 protein in murine and human thymocytes and in peripheral T lymphocytes.
Bcl-2 affects survival but not neuronal differentiation of PC12 cells.
Bcl-2 functions in an antioxidant pathway to prevent apoptosis.
Targeting of Bcl-2 to the mitochondrial outer membrane by a COOH-terminal signal anchor sequence.
Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death.
BCL2 protein is topographically restricted in tissues characterized by apoptotic cell death.
Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death.
Deregulated Bcl-2-immunoglobulin transgene expands a resting but responsive immunoglobulin M and D-expressing B-cell population.
Yang E, Zha J, Jockel J, Boise LH, Thompson CB, Korsmeyer SJ
Cell 1995 Jan 27;80(2):285-91
Cell 1995 Jan 27;80(2):285-91
BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heterodimerization with Bax.
Yin XM, Oltvai ZN, Korsmeyer SJ
Nature 1994 May 26;369(6478):321-3
Nature 1994 May 26;369(6478):321-3
Bcl-2 and Bcl-x: regulatory switches for lymphoid death and survival.
Núñez G, Merino R, Grillot D, González-García M
Immunology today 1994 Dec;15(12):582-8
Immunology today 1994 Dec;15(12):582-8
Bcl-2 blocks p53-dependent apoptosis.
Chiou SK, Rao L, White E
Molecular and cellular biology 1994 Apr;14(4):2556-63
Molecular and cellular biology 1994 Apr;14(4):2556-63
Latent membrane protein of Epstein-Barr virus induces cellular phenotypes independently of expression of Bcl-2.
Martin JM, Veis D, Korsmeyer SJ, Sugden B
Journal of virology 1993 Sep;67(9):5269-78
Journal of virology 1993 Sep;67(9):5269-78
Expression of the Bcl-2 protein in murine and human thymocytes and in peripheral T lymphocytes.
Veis DJ, Sentman CL, Bach EA, Korsmeyer SJ
Journal of immunology (Baltimore, Md. : 1950) 1993 Sep 1;151(5):2546-54
Journal of immunology (Baltimore, Md. : 1950) 1993 Sep 1;151(5):2546-54
Bcl-2 affects survival but not neuronal differentiation of PC12 cells.
Batistatou A, Merry DE, Korsmeyer SJ, Greene LA
The Journal of neuroscience : the official journal of the Society for Neuroscience 1993 Oct;13(10):4422-8
The Journal of neuroscience : the official journal of the Society for Neuroscience 1993 Oct;13(10):4422-8
Bcl-2 functions in an antioxidant pathway to prevent apoptosis.
Hockenbery DM, Oltvai ZN, Yin XM, Milliman CL, Korsmeyer SJ
Cell 1993 Oct 22;75(2):241-51
Cell 1993 Oct 22;75(2):241-51
Targeting of Bcl-2 to the mitochondrial outer membrane by a COOH-terminal signal anchor sequence.
Nguyen M, Millar DG, Yong VW, Korsmeyer SJ, Shore GC
The Journal of biological chemistry 1993 Dec 5;268(34):25265-8
The Journal of biological chemistry 1993 Dec 5;268(34):25265-8
Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death.
Oltvai ZN, Milliman CL, Korsmeyer SJ
Cell 1993 Aug 27;74(4):609-19
Cell 1993 Aug 27;74(4):609-19
BCL2 protein is topographically restricted in tissues characterized by apoptotic cell death.
Hockenbery DM, Zutter M, Hickey W, Nahm M, Korsmeyer SJ
Proceedings of the National Academy of Sciences of the United States of America 1991 Aug 15;88(16):6961-5
Proceedings of the National Academy of Sciences of the United States of America 1991 Aug 15;88(16):6961-5
Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death.
Hockenbery D, Nuñez G, Milliman C, Schreiber RD, Korsmeyer SJ
Nature 1990 Nov 22;348(6299):334-6
Nature 1990 Nov 22;348(6299):334-6
Deregulated Bcl-2-immunoglobulin transgene expands a resting but responsive immunoglobulin M and D-expressing B-cell population.
McDonnell TJ, Nunez G, Platt FM, Hockenberry D, London L, McKearn JP, Korsmeyer SJ
Molecular and cellular biology 1990 May;10(5):1901-7
Molecular and cellular biology 1990 May;10(5):1901-7
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