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Western blot
ImmunoprecipitationAntibody data
- Antibody Data
- Antigen structure
- References [10]
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- Product number
- ABIN967318 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-B-Cell CLL/lymphoma 2 (BCL2) antibody
- Antibody type
- Monoclonal
- Antigen
- Human Bcl-2
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- 4D7
- Vial size
- 150 µg
- Concentration
- 0.25 mg/ml
- Storage
- Store undiluted at -20°C.
Submitted references Nonionic detergents induce dimerization among members of the Bcl-2 family.
Estrogen promotes chemotherapeutic drug resistance by a mechanism involving Bcl-2 proto-oncogene expression in human breast cancer cells.
R-Ras promotes apoptosis caused by growth factor deprivation via a Bcl-2 suppressible mechanism.
Investigation of the subcellular distribution of the bcl-2 oncoprotein: residence in the nuclear envelope, endoplasmic reticulum, and outer mitochondrial membranes.
Structure-function analysis of the Bcl-2 oncoprotein. Addition of a heterologous transmembrane domain to portions of the Bcl-2 beta protein restores function as a regulator of cell survival.
A strategy for generating monoclonal antibodies against recombinant baculovirus-produced proteins: application to the Bcl-2 oncoprotein.
Differential expression of bcl2 protooncogene in neuroblastoma and other human tumor cell lines of neural origin.
Expression of the bcl-2 oncogene protein is not specific for the 14;18 chromosomal translocation.
Regulation of bcl-2 proto-oncogene expression during normal human lymphocyte proliferation.
Involvement of the bcl-2 gene in human follicular lymphoma.
Hsu YT, Youle RJ
The Journal of biological chemistry 1997 May 23;272(21):13829-34
The Journal of biological chemistry 1997 May 23;272(21):13829-34
Estrogen promotes chemotherapeutic drug resistance by a mechanism involving Bcl-2 proto-oncogene expression in human breast cancer cells.
Teixeira C, Reed JC, Pratt MA
Cancer research 1995 Sep 1;55(17):3902-7
Cancer research 1995 Sep 1;55(17):3902-7
R-Ras promotes apoptosis caused by growth factor deprivation via a Bcl-2 suppressible mechanism.
Wang HG, Millan JA, Cox AD, Der CJ, Rapp UR, Beck T, Zha H, Reed JC
The Journal of cell biology 1995 May;129(4):1103-14
The Journal of cell biology 1995 May;129(4):1103-14
Investigation of the subcellular distribution of the bcl-2 oncoprotein: residence in the nuclear envelope, endoplasmic reticulum, and outer mitochondrial membranes.
Krajewski S, Tanaka S, Takayama S, Schibler MJ, Fenton W, Reed JC
Cancer research 1993 Oct 1;53(19):4701-14
Cancer research 1993 Oct 1;53(19):4701-14
Structure-function analysis of the Bcl-2 oncoprotein. Addition of a heterologous transmembrane domain to portions of the Bcl-2 beta protein restores function as a regulator of cell survival.
Tanaka S, Saito K, Reed JC
The Journal of biological chemistry 1993 May 25;268(15):10920-6
The Journal of biological chemistry 1993 May 25;268(15):10920-6
A strategy for generating monoclonal antibodies against recombinant baculovirus-produced proteins: application to the Bcl-2 oncoprotein.
Reed JC, Tanaka S, Cuddy M, Cho D, Smith J, Kallen R, Saragovi HU, Torigoe T
Analytical biochemistry 1992 Aug 15;205(1):70-6
Analytical biochemistry 1992 Aug 15;205(1):70-6
Differential expression of bcl2 protooncogene in neuroblastoma and other human tumor cell lines of neural origin.
Reed JC, Meister L, Tanaka S, Cuddy M, Yum S, Geyer C, Pleasure D
Cancer research 1991 Dec 15;51(24):6529-38
Cancer research 1991 Dec 15;51(24):6529-38
Expression of the bcl-2 oncogene protein is not specific for the 14;18 chromosomal translocation.
Pezzella F, Tse AG, Cordell JL, Pulford KA, Gatter KC, Mason DY
The American journal of pathology 1990 Aug;137(2):225-32
The American journal of pathology 1990 Aug;137(2):225-32
Regulation of bcl-2 proto-oncogene expression during normal human lymphocyte proliferation.
Reed JC, Tsujimoto Y, Alpers JD, Croce CM, Nowell PC
Science (New York, N.Y.) 1987 Jun 5;236(4806):1295-9
Science (New York, N.Y.) 1987 Jun 5;236(4806):1295-9
Involvement of the bcl-2 gene in human follicular lymphoma.
Tsujimoto Y, Cossman J, Jaffe E, Croce CM
Science (New York, N.Y.) 1985 Jun 21;228(4706):1440-3
Science (New York, N.Y.) 1985 Jun 21;228(4706):1440-3
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