ABIN968024

antibody from antibodies-online

Targeting: BCL2 Bcl-2, PPP1R50

Western blot (Data presented on provider website)

Immunocytochemistry (Recommended by provider)

Immunoprecipitation (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN968024

Provider

antibodies-online

Product name

anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 49-179) antibody

Antibody type

Monoclonal

Antigen

Human Bcl-2

Reactivity

Human

Host

Mouse

Isotype

IgG

Antibody clone number

7

Vial size

50 µg

Concentration

250 µg/ml

Storage

Store undiluted at -20°C.

References

Submitted references

The retinoblastoma protein binds the promoter of the survival gene bcl-2 and regulates its transcription in epithelial cells through transcription factor AP-2.

Decary S, Decesse JT, Ogryzko V, Reed JC, Naguibneva I, Harel-Bellan A, Cremisi CE
Molecular and cellular biology 2002 Nov;22(22):7877-88

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Phosphoinositide 3-kinase regulates beta2-adrenergic receptor endocytosis by AP-2 recruitment to the receptor/beta-arrestin complex.

Naga Prasad SV, Laporte SA, Chamberlain D, Caron MG, Barak L, Rockman HA
The Journal of cell biology 2002 Aug 5;158(3):563-75

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Bcl-2 targets protein phosphatase 1 alpha to Bad.

Ayllón V, Cayla X, García A, Roncal F, Fernández R, Albar JP, Martínez C, Rebollo A
Journal of immunology (Baltimore, Md. : 1950) 2001 Jun 15;166(12):7345-52

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alpha 7 nicotinic receptor transduces signals to phosphatidylinositol 3-kinase to block A beta-amyloid-induced neurotoxicity.

Kihara T, Shimohama S, Sawada H, Honda K, Nakamizo T, Shibasaki H, Kume T, Akaike A
The Journal of biological chemistry 2001 Apr 27;276(17):13541-6

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Analysis of the structure, transcripts, and protein products of bcl-2, the gene involved in human follicular lymphoma.

Tsujimoto Y, Croce CM
Proceedings of the National Academy of Sciences of the United States of America 1986 Jul;83(14):5214-8