RA0306

antibody from Oursmab

Targeting: MUC16 CA125, FLJ14303

Western blot (Data presented on provider website)

Functional assay (Recommended by provider)

Antibody Data

Product number

RA0306

Provider

Oursmab

Product name

Abagovomab (Biosimilar Reference Antibody) (Idiotypic monoclonal antibody targeting CA125)

Antibody type

Monoclonal

Description

Abagovomab is a murine monoclonal anti-idiotypic antibody (MW ~150 kDa) that mimics the cancer antigen CA125. It was developed as a therapeutic vaccine for the treatment of ovarian cancer. The antibody functions by stimulating the patient's immune system to produce anti-anti-idiotypic antibodies, which in turn generate a specific immune response against CA125-expressing tumor cells. While demonstrating immunogenicity in clinical trials, its development was discontinued following Phase III trials which did not meet the primary endpoint of significantly improving recurrence-free survival.

Reactivity

Human

Isotype

IgG

Vial size

100 ¦Ìg,1 mg,5 mg,10 mg,25 mg,50 mg,100 mg

Concentration

Bottled at the concentration indicated on the vial.

Storage

Store at -20¡ãC or -80¡ãC. Avoid repeated freeze.