RA0059

antibody from Oursmab

Targeting: CALCA CALC1, CGRP, CGRP-alpha

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunocytochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Functional assay (Recommended by provider)

Antibody Data

Product number

RA0059

Provider

Oursmab

Product name

Eptinezumab (Biosimilar Reference Antibody) (CALCA and CALCB)

Antibody type

Monoclonal

Description

Eptinezumab is a humanized immunoglobulin G1 (IgG1) monoclonal antibody specifically approved for the preventive treatment of migraine in adults. It represents a targeted therapy within the class of calcitonin gene-related peptide (CGRP) pathway inhibitors. Eptinezumab functions as a highly selective CGRP antagonist, designed to bind and neutralize the CGRP ligand in the bloodstream. By blocking CGRP from interacting with its receptors, it aims to prevent the initiation and propagation of the neuroinflammatory cascade believed to underlie migraine attacks, thereby reducing migraine frequency and severity.

Reactivity

Human

Isotype

IgG

Vial size

100 ¦Ìg,1 mg,5 mg,10 mg,25 mg,50 mg,100 mg

Concentration

Bottled at the concentration indicated on the vial.

Storage

Store at -20¡ãC or -80¡ãC. Avoid repeated freeze.