FABVC-H278

antibody from Creative Biolabs

Targeting: CD3E

No application information provided.

Antibody Data

Product number

FABVC-H278

Provider

Creative Biolabs

Product name

Recombinant Human Anti-CD3 x Human Anti-PSMA Bispecific Antibody (Fab-scFv-Fc)

Antibody type

Monoclonal

Description

Recombinant Anti-CD3 x Anti-PSMA Bispecific Antibody (Fab-scFv-Fc) requires expression of three polypeptide chains, encoding two heavy chains (Fc-containing chains) and one light chain, respectively. The Fab of anti-CD3 antibody variable domain is fused to the Fc-knob domain with a hinge region and the same as the scFv of anti-PSMA to the Fc-hole domain, or vice versa. The Fab-Fc and scFv-Fc fragments can be paired via the interaction of the Fc regions. This BsAb can retarget T cells to tumor cells. It is designed for the research of Prostate cancer therapy.

Reactivity

Human