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- Antigen structure
- References [22]
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- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 12540-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12540-1-AP, RRID:AB_2273990
- Product name
- Amylase Alpha antibody
- Antibody type
- Polyclonal
- Description
- Amylase Alpha antibody (Cat. #12540-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references The vagus nerve activated by inflammation co-transmits acute visceral pain via the NTS-PVN pathway.
From stem cells to nanomedicine: A multimodal approach targeting pancreatic fibrosis via MFGE8-dependent ANXA1-SMAD2/3 axis.
Tailored "Three-stage booster" nano-extinguisher for synergistic treatment of severe acute pancreatitis by rectifying mitochondrial dysfunction and inhibiting pancreatic autodigestion.
Deficiency of Mesencephalic Astrocyte-derived Neurotrophic Factor Aggravates Acute Pancreatitis in Mice.
Engineered Stem Cell Booster Breaks Pathological Barriers to Treat Chronic Pancreatitis.
Inflammation and Acinar Cell Dual-Targeting Nanomedicines for Synergistic Treatment of Acute Pancreatitis via Ca(2+) Homeostasis Regulation and Pancreas Autodigestion Inhibition.
Gastrodin ameliorates acute pancreatitis by modulating macrophage inflammation cascade via inhibition the p38/NF-κB pathway.
hP-MSCs attenuate severe acute pancreatitis in mice via inhibiting NLRP3 inflammasome-mediated acinar cell pyroptosis.
Biomimetic Trypsin-Responsive Structure-Bridged Mesoporous Organosilica Nanomedicine for Precise Treatment of Acute Pancreatitis.
ATP citrate lyase ablation hampers exocrine regeneration via TLR4/NF-kappaB signaling after acute pancreatitis in mice.
Micheliolide ameliorates severe acute pancreatitis in mice through potentiating Nrf2-mediated anti-inflammation and anti-oxidation effects.
Pyrazole derivative Z10 ameliorates acute pancreatitis by inhibiting the ERK/Ddt pathway.
Injectable decellularized extracellular matrix hydrogel promotes salivary gland regeneration via endogenous stem cell recruitment and suppression of fibrogenesis.
Alterations in histology of the aging salivary gland and correlation with the glandular inflammatory microenvironment.
Colonic mucin-2 attenuates acute necrotizing pancreatitis in rats by modulating intestinal homeostasis.
Decreased neutrophil counts prolong inflammation in acute pancreatitis and cause inflammation spillover to distant organs.
Clinicopathological characteristics of pancreatic acinar cell metaplasia associated with Helicobacter pylori infection.
SULF2 enhances GDF15-SMAD axis to facilitate the initiation and progression of pancreatic cancer.
Berberine inhibits pancreatic intraepithelial neoplasia by inhibiting glycolysis via the adenosine monophosphate -activated protein kinase pathway.
Serotonin-RhoA/ROCK axis promotes acinar-to-ductal metaplasia in caerulein-induced chronic pancreatitis.
c-Fos/ERK promotes the progression from pancreatic intraepithelial neoplasia to pancreatic ductal adenocarcinoma.
Vacuolization of mucolipidosis type II mouse exocrine gland cells represents accumulation of autolysosomes.
Zhao YT, Zheng ZK, Yang XH, Duan YJ, Xie X, Chen L, Xu YZ, Zheng Y, Liu YQ, Zhao YY, Tang XQ, Shi JM, Xie JD, Qin C, Xin WJ, Wu Y, Deng J, Xu T
Brain, behavior, and immunity 2026 Mar 31;136:106551
Brain, behavior, and immunity 2026 Mar 31;136:106551
From stem cells to nanomedicine: A multimodal approach targeting pancreatic fibrosis via MFGE8-dependent ANXA1-SMAD2/3 axis.
Xie W, Luo T, Tang G, Ma Z, Gong J, Yang T, Zhou J, Song Z
International journal of biological macromolecules 2026 Jan;338(Pt 1):149698
International journal of biological macromolecules 2026 Jan;338(Pt 1):149698
Tailored "Three-stage booster" nano-extinguisher for synergistic treatment of severe acute pancreatitis by rectifying mitochondrial dysfunction and inhibiting pancreatic autodigestion.
Yan J, Liu H, Xu Y, Sun X, Meng X, Wei S, Li Z, Jin X, Liu J, Wang X, Cui P, He Z
Acta biomaterialia 2025 Jun 15;200:569-590
Acta biomaterialia 2025 Jun 15;200:569-590
Deficiency of Mesencephalic Astrocyte-derived Neurotrophic Factor Aggravates Acute Pancreatitis in Mice.
Li H, Ma M, Wen W, Leidinger MR, Hu D, Zhang Z, Lin H, Luo J
bioRxiv : the preprint server for biology 2025 Aug 2;
bioRxiv : the preprint server for biology 2025 Aug 2;
Engineered Stem Cell Booster Breaks Pathological Barriers to Treat Chronic Pancreatitis.
Han H, Chen BT, Liu Y, Qi L, Xing L, Wang H, Zhao M, Zhang C, Yu P, Wei N, Wang J, Zhou F, Wang GJ, Cheng XW, Huang ZJ, Li L, Jiang HL
Advanced materials (Deerfield Beach, Fla.) 2025 Apr;37(14):e2416261
Advanced materials (Deerfield Beach, Fla.) 2025 Apr;37(14):e2416261
Inflammation and Acinar Cell Dual-Targeting Nanomedicines for Synergistic Treatment of Acute Pancreatitis via Ca(2+) Homeostasis Regulation and Pancreas Autodigestion Inhibition.
Wang Y, Wang X, Zhang X, Zhang B, Meng X, Qian D, Xu Y, Yu L, Yan X, He Z
ACS nano 2024 May 7;18(18):11778-11803
ACS nano 2024 May 7;18(18):11778-11803
Gastrodin ameliorates acute pancreatitis by modulating macrophage inflammation cascade via inhibition the p38/NF-κB pathway.
Jiang Y, Wu H, Peng Y, He P, Qian S, Lin H, Chen H, Qian R, Wang D, Chu M, Ji W, Guo X, Shan X
International immunopharmacology 2024 Mar 10;129:111593
International immunopharmacology 2024 Mar 10;129:111593
hP-MSCs attenuate severe acute pancreatitis in mice via inhibiting NLRP3 inflammasome-mediated acinar cell pyroptosis.
Lyu S, Liu S, Guo X, Zhang Y, Liu Z, Shi S, Li W, Pei J, Fan Y, Sun H
Apoptosis : an international journal on programmed cell death 2024 Jun;29(5-6):920-933
Apoptosis : an international journal on programmed cell death 2024 Jun;29(5-6):920-933
Biomimetic Trypsin-Responsive Structure-Bridged Mesoporous Organosilica Nanomedicine for Precise Treatment of Acute Pancreatitis.
Wang Y, Qian D, Wang X, Zhang X, Li Z, Meng X, Yu L, Yan X, He Z
ACS nano 2024 Jul 23;18(29):19283-19302
ACS nano 2024 Jul 23;18(29):19283-19302
ATP citrate lyase ablation hampers exocrine regeneration via TLR4/NF-kappaB signaling after acute pancreatitis in mice.
Hong YP, Yan X, Ding QZ, Zhang ZB
International immunopharmacology 2024 Dec 25;143(Pt 3):113485
International immunopharmacology 2024 Dec 25;143(Pt 3):113485
Micheliolide ameliorates severe acute pancreatitis in mice through potentiating Nrf2-mediated anti-inflammation and anti-oxidation effects.
Wu CY, Wang KQ, Qin YY, Wang HW, Wu MM, Zhu XD, Lu XY, Zhu MM, Lu CS, Hu QQ
International immunopharmacology 2024 Dec 25;143(Pt 2):113490
International immunopharmacology 2024 Dec 25;143(Pt 2):113490
Pyrazole derivative Z10 ameliorates acute pancreatitis by inhibiting the ERK/Ddt pathway.
Zeng W, Pan J, Li W, Huang B, Lu X, Xiao J
Biochimica et biophysica acta. Molecular basis of disease 2024 Apr;1870(4):167088
Biochimica et biophysica acta. Molecular basis of disease 2024 Apr;1870(4):167088
Injectable decellularized extracellular matrix hydrogel promotes salivary gland regeneration via endogenous stem cell recruitment and suppression of fibrogenesis.
Wang T, Huang Q, Rao Z, Liu F, Su X, Zhai X, Ma J, Liang Y, Quan D, Liao G, Bai Y, Zhang S
Acta biomaterialia 2023 Oct 1;169:256-272
Acta biomaterialia 2023 Oct 1;169:256-272
Alterations in histology of the aging salivary gland and correlation with the glandular inflammatory microenvironment.
Li N, Ye Y, Wu Y, Li L, Hu J, Luo D, Li Y, Yang J, Gao Y, Hai W, Xie Y, Jiang L
iScience 2023 May 19;26(5):106571
iScience 2023 May 19;26(5):106571
Colonic mucin-2 attenuates acute necrotizing pancreatitis in rats by modulating intestinal homeostasis.
Huang Z, Wu H, Fan J, Mei Q, Fu Y, Yin N, Xu B, Luo S, Li B, Ni J, Huang C, Hu J, Zeng Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Jul;37(7):e22994
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Jul;37(7):e22994
Decreased neutrophil counts prolong inflammation in acute pancreatitis and cause inflammation spillover to distant organs.
Fukuda Y, Mori K, Okada H, Tomita H, Suzuki K, Takada C, Kamidani R, Kawasaki Y, Fukuda H, Minamiyama T, Nishio A, Shimada T, Kuroda A, Uchida A, Kitagawa Y, Fukuta T, Miyake T, Yoshida T, Suzuki A, Tetsuka N, Yoshida S, Ogura S
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2023 Dec;23(8):911-918
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2023 Dec;23(8):911-918
Clinicopathological characteristics of pancreatic acinar cell metaplasia associated with Helicobacter pylori infection.
Fuchino T, Wada Y, Kodama M, Mukaisho KI, Mizukami K, Okimoto T, Kushima R, Murakami K
BMC gastroenterology 2022 Jun 7;22(1):289
BMC gastroenterology 2022 Jun 7;22(1):289
SULF2 enhances GDF15-SMAD axis to facilitate the initiation and progression of pancreatic cancer.
He R, Shi J, Xu D, Yang J, Shen Y, Jiang YS, Tao L, Yang M, Fu X, Yang JY, Liu D, Huo Y, Shen X, Lu P, Niu N, Sun YW, Xue J, Liu W
Cancer letters 2022 Jul 10;538:215693
Cancer letters 2022 Jul 10;538:215693
Berberine inhibits pancreatic intraepithelial neoplasia by inhibiting glycolysis via the adenosine monophosphate -activated protein kinase pathway.
Liu M, Yang Y, Kang W, Liu Y, Tao X, Li X, Pan Y
European journal of pharmacology 2022 Jan 15;915:174680
European journal of pharmacology 2022 Jan 15;915:174680
Serotonin-RhoA/ROCK axis promotes acinar-to-ductal metaplasia in caerulein-induced chronic pancreatitis.
Tao X, Chen Q, Li N, Xiang H, Pan Y, Qu Y, Shang D, Go VLW, Xue J, Sun Y, Zhang Z, Guo J, Xiao GG
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109999
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109999
c-Fos/ERK promotes the progression from pancreatic intraepithelial neoplasia to pancreatic ductal adenocarcinoma.
You L, Ren X, Du Y, Zhao W, Cui M, Chen G, Zhao Y
Oncology reports 2016 Dec;36(6):3413-3420
Oncology reports 2016 Dec;36(6):3413-3420
Vacuolization of mucolipidosis type II mouse exocrine gland cells represents accumulation of autolysosomes.
Boonen M, van Meel E, Oorschot V, Klumperman J, Kornfeld S
Molecular biology of the cell 2011 Apr 15;22(8):1135-47
Molecular biology of the cell 2011 Apr 15;22(8):1135-47
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 12540-1-AP(AMY2B antibody) at dilution of 1:400
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The AMY2B antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human AMY2B. This antibody recognizes human,mouse,rat antigen. The AMY2B antibody has been validated for the following applications: ELISA, WB, IHC analysis.
