Antibody data

Product number
BS60357 - Provider product page
Provider
Bioworld Technology, Inc
Product name
CD8A polyclonal antibody
Antibody type
Polyclonal
Antigen
A synthetic peptide corresponding to residues in Human CD8A.
Description
The T cell receptor (TCR) is a heterodimer composed of either Ï« and ÉÇ or ÎÛ and Ñ´ chains. CD3 chains and the CD4 or CD8 co-receptors are also required for efficient signal transduction through the TCR. The TCR is expressed on T helper and T cytotoxic cells that can be distinguished by their expression of CD4 and CD8. T helper cells express CD4 proteins, while T cytotoxic cells display CD8. CD8 (also designated Leu-2 or T8), a cell surface glycoprotein, is a two chain complex (Ï«Ï« or Ï«ÉÇ) receptor that binds class I MHC molecules presented by the antigen-presenting cell (APC). A primary function of CD8 is to facilitate antigen recognition by the TCR and to strengthen the avidity of the TCR-antigen interactions. An additional role for CD8-expressing T cells may be to maintain low levels of HIV expression.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
CD8A protein structure - BS60357 shown in red.