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- Antibody Data
- Antigen structure
- References [147]
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- Product number
- 66868-1-Ig - Provider product page
- Provider
- Proteintech Group
- Product name
- CD8 antibody
- Antibody type
- Monoclonal
- Description
- CD8 antibody (Cat. #66868-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 1G2B10
- Vial size
- 20ul, 150ul
Submitted references Coactosin-Like Protein 1 (COTL1) Could Be an Immunological and Prognostic Biomarker: From Pan-Cancer Analysis to Low-Grade Glioma Validation.
Platinum-based neoadjuvant chemotherapy upregulates STING/IFN pathway expression and promotes TILs infiltration in NSCLC.
Exploring the impact of PDGFD in osteosarcoma metastasis through single-cell sequencing analysis.
Integrative analysis of the cuproptosis-related gene ATP7B in the prognosis and immune infiltration of IDH1 wild-type glioma.
NDRG1 overcomes resistance to immunotherapy of pancreatic ductal adenocarcinoma through inhibiting ATG9A-dependent degradation of MHC-1.
Targeting autophagy overcomes cancer-intrinsic resistance to CAR-T immunotherapy in B-cell malignancies.
Pirin Inhibits FAS-Mediated Apoptosis to Support Colorectal Cancer Survival.
Modified Biejia Jianwan decoction restrains PD-L1-mediated immune evasion through the HIF-1α/STAT3/NF-κB signaling pathway.
WTAP regulates the production of reactive oxygen species, promotes malignant progression, and is closely related to the tumor microenvironment in glioblastoma.
The construction of modular universal chimeric antigen receptor T (MU-CAR-T) cells by covalent linkage of allogeneic T cells and various antibody fragments.
Pan-Cancer Single-Cell and Spatial-Resolved Profiling Reveals the Immunosuppressive Role of APOE+ Macrophages in Immune Checkpoint Inhibitor Therapy.
GSK0660 enhances antitumor immunotherapy by reducing PD-L1 expression.
Distinctive multicellular immunosuppressive hubs confer different intervention strategies for left- and right-sided colon cancers.
Transdermal delivery of Fn14 siRNA using a novel composite ionic liquid for treatment of psoriasis-like skin lesions.
Gut microbiota modulate CD8(+) T cell immunity in gastric cancer through Butyrate/GPR109A/HOPX.
Pumilio1 regulates NPM3/NPM1 axis to promote PD-L1-mediated immune escape in gastric cancer.
UPP1 promotes lung adenocarcinoma progression through the induction of an immunosuppressive microenvironment.
Blockade of C5a receptor unleashes tumor-associated macrophage antitumor response and enhances CXCL9-dependent CD8(+) T cell activity.
Nicotinamide metabolism face-off between macrophages and fibroblasts manipulates the microenvironment in gastric cancer.
The prognostic value of CD8(+) CTLs, CD163(+) TAMs, and PDL1 expression in the tumor microenvironment of primary central nervous system lymphoma.
Immune characteristics associated with lymph node metastasis in early-stage NSCLC.
Tumor-activated IL-2 mRNA delivered by lipid nanoparticles for cancer immunotherapy.
Mn-Anti-CTLA4-CREKA-Sericin Nanotheragnostics for Enhanced Magnetic Resonance Imaging and Tumor Immunotherapy.
Glycyrrhetinic acid inhibits non-small cell lung cancer via promotion of Prdx6- and caspase-3-mediated mitochondrial apoptosis.
Hippo-signaling-controlled MHC class I antigen processing and presentation pathway potentiates antitumor immunity.
Diaphorobacter nitroreducens synergize with oxaliplatin to reduce tumor burden in mice with lung adenocarcinoma.
Scutellarin activates IDH1 to exert antitumor effects in hepatocellular carcinoma progression.
ISG15 is a potential therapeutic target for osteosarcoma: a comprehensive analysis based on bioinformatics and in vitro experiments.
Tumor-secreted lactate contributes to an immunosuppressive microenvironment and affects CD8 T-cell infiltration in glioblastoma.
FANCI serve as a prognostic biomarker correlated with immune infiltrates in skin cutaneous melanoma.
A novel prognostic signatures based on metastasis- and immune-related gene pairs for colorectal cancer.
PD-L1 and tumor-infiltrating CD8(+) lymphocytes are correlated with clinical characteristics in pediatric and adolescent pituitary adenomas.
LRPPRC facilitates tumor progression and immune evasion through upregulation of m(6)A modification of PD-L1 mRNA in hepatocellular carcinoma.
Establishment and validation of an immune infiltration predictive model for ovarian cancer.
Single-cell and bulk sequencing analyses reveal the immune suppressive role of PTPN6 in glioblastoma.
Ki67-targeted oncolytic adenovirus expressing IL-15 improves intratumoral T cell infiltration and PD-L1 expression in glioblastoma.
METTL3 inhibition induced by M2 macrophage-derived extracellular vesicles drives anti-PD-1 therapy resistance via M6A-CD70-mediated immune suppression in thyroid cancer.
Targeting TNFAIP2 induces immunogenic cell death and sensitizes glioblastoma multiforme to anti-PD-1 therapy.
A Booster for Radiofrequency Ablation: Advanced Adjuvant Therapy via In Situ Nanovaccine Synergized with Anti-programmed Death Ligand 1 Immunotherapy for Systemically Constraining Hepatocellular Carcinoma.
Deubiquitinase inhibitor PR-619 potentiates colon cancer immunotherapy by inducing ferroptosis.
Mesothelin-targeted CAR-T therapy combined with irinotecan for the treatment of solid cancer.
Engineering high-affinity dual targeting cellular nanovesicles for optimised cancer immunotherapy.
Low-dose radiotherapy combined with dual PD-L1 and VEGFA blockade elicits antitumor response in hepatocellular carcinoma mediated by activated intratumoral CD8(+) exhausted-like T cells.
TWEAK and Fn14 are overexpressed in immune-mediated necrotizing myopathy: implications for muscle damage and repair.
FAM171B stabilizes vimentin and enhances CCL2-mediated TAM infiltration to promote bladder cancer progression.
Combination of novel oncolytic herpesvirus with paclitaxel as an efficient strategy for breast cancer therapy.
Exploration of (68)Ga-labelled prostate-specific membrane antigen-11 PET/CT parameters for identifying PBRM1 status in primary clear cell renal cell carcinoma.
Exosomal PD‑L1 promotes the formation of an immunosuppressive microenvironment in gastric diffuse large B‑cell lymphoma.
High baseline tumor burden-associated macrophages promote an immunosuppressive microenvironment and reduce the efficacy of immune checkpoint inhibitors through the IGFBP2-STAT3-PD-L1 pathway.
Prognostic value of CD8-to-EGFR ratio in salivary microvesicles of patients with oral squamous cell carcinoma.
GBP2 promotes clear cell renal cell carcinoma progression through immune infiltration and regulation of PD‑L1 expression via STAT1 signaling.
Oncogenic epidermal growth factor receptor signal-induced histone deacetylation suppresses chemokine gene expression in human lung adenocarcinoma.
Anti-signal recognition particle positive necrotizing myopathy-sjogren's syndrome overlap syndrome: a descriptive study on clinical and myopathology features.
PYCR1 promotes the malignant progression of lung cancer through the JAK-STAT3 signaling pathway via PRODH-dependent glutamine synthesize.
An integrated bioinformatic investigation of focal adhesion-related genes in glioma followed by preliminary validation of COL1A2 in tumorigenesis.
Optogenetic engineered umbilical cord MSC-derived exosomes for remodeling of the immune microenvironment in diabetic wounds and the promotion of tissue repair.
STAT4, a potential predictor of prognosis, promotes CD8 T‑cell infiltration in ovarian serous carcinoma by inducing CCL5 secretion.
An inflammation-associated ferroptosis signature optimizes the diagnosis, prognosis evaluation and immunotherapy options in hepatocellular carcinoma.
Inhibition of FGFR3 upregulates MHC-I and PD-L1 via TLR3/NF-kB pathway in muscle-invasive bladder cancer.
Intra-tumoral infiltration of adipocyte facilitates the activation of antitumor immune response in pancreatic ductal adenocarcinoma.
Virulence factors and mechanisms of paediatric pneumonia caused by Enterococcus faecalis.
Inhibition of Checkpoint Kinase 1 (CHK1) Upregulates Interferon Regulatory Factor 1 (IRF1) to Promote Apoptosis and Activate Anti-Tumor Immunity via MICA in Hepatocellular Carcinoma (HCC).
Expression of glucose transporter-1 in follicular lymphoma affected tumor-infiltrating immunocytes and was related to progression of disease within 24 months.
The PD-L1 Expression and Tumor-Infiltrating Immune Cells Predict an Unfavorable Prognosis in Pancreatic Ductal Adenocarcinoma and Adenosquamous Carcinoma.
HNRNPL induced circFAM13B increased bladder cancer immunotherapy sensitivity via inhibiting glycolysis through IGF2BP1/PKM2 pathway.
HRS Regulates Small Extracellular Vesicle PD-L1 Secretion and Is Associated with Anti-PD-1 Treatment Efficacy.
Apoptotic tumor cell-derived microparticles loading Napabucasin inhibit CSCs and synergistic immune therapy.
Proteomic and single-cell landscape reveals novel pathogenic mechanisms of HBV-infected intrahepatic cholangiocarcinoma.
Behind the Indolent Facade: Uncovering the Molecular Features and Malignancy Potential in Lung Minimally Invasive Adenocarcinoma by Single-Cell Transcriptomics.
PPARγ agonist inhibits c-Myc-mediated colorectal cancer tumor immune escape.
Single cell transcriptomic analyses implicate an immunosuppressive tumor microenvironment in pancreatic cancer liver metastasis.
Single-cell dissection of cervical cancer reveals key subsets of the tumor immune microenvironment.
CT-based radiomics signature to predict CD8+ tumor infiltrating lymphocytes in non-small-cell lung cancer.
Regulation of CD8(+) T cells infiltration and immunotherapy by circMGA/HNRNPL complex in bladder cancer.
MAX transcriptionally enhances PD-L1 to inhibit CD8+ T cell-mediated killing of lung adenocarcinoma cells.
Characterization of myeloid signature genes for predicting prognosis and immune landscape in Ewing sarcoma.
Self-Assembly Catalase Nanocomplex Conveyed by Bacterial Vesicles for Oxygenated Photodynamic Therapy and Tumor Immunotherapy.
CLEC1B is a Promising Prognostic Biomarker and Correlated with Immune Infiltration in Hepatocellular Carcinoma.
A Comparison for Type 2 Cytokines and Lesional Inflammatory Infiltrations in Bullous Pemphigoid and Atopic Dermatitis.
Identification of a novel immune gene panel in tongue squamous cell carcinoma.
Single-cell sequencing reveals effects of chemotherapy on the immune landscape and TCR/BCR clonal expansion in a relapsed ovarian cancer patient.
Identification of ST3GAL5 as a prognostic biomarker correlating with CD8(+) T cell exhaustion in clear cell renal cell carcinoma.
CEP192 is a novel prognostic marker and correlates with the immune microenvironment in hepatocellular carcinoma.
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Single-cell RNA sequencing reveals distinct immunology profiles in human keloid.
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A novel ganglioside-related risk signature can reveal the distinct immune landscape of neuroblastoma and predict the immunotherapeutic response.
Identification and experimental validation of a tumor-infiltrating lymphocytes-related long noncoding RNA signature for prognosis of clear cell renal cell carcinoma.
A pan-cancer and single-cell sequencing analysis of CD161, a promising onco-immunological biomarker in tumor microenvironment and immunotherapy.
A specific immune signature for predicting the prognosis of glioma patients with IDH1-mutation and guiding immune checkpoint blockade therapy.
Machine learning-based identification of tumor-infiltrating immune cell-associated lncRNAs for improving outcomes and immunotherapy responses in patients with low-grade glioma.
Label-free LC-MS/MS proteomics analyses reveal CLIC1 as a predictive biomarker for bladder cancer staging and prognosis.
Screening of an individualized treatment strategy for an advanced gallbladder cancer using patient-derived tumor xenograft and organoid models.
Oncolytic adenovirus with MUC16-BiTE shows enhanced antitumor immune response by reversing the tumor microenvironment in PDX model of ovarian cancer.
Identify the Prognostic and Immune Profile of VSIR in the Tumor Microenvironment: A Pan-Cancer Analysis.
Immunohistochemical analysis of PD-L1 and tumor-infiltrating immune cells expression in the tumor microenvironment of primary signet ring cell carcinoma of the prostate.
Sphingosine kinase 1 promotes tumor immune evasion by regulating the MTA3-PD-L1 axis.
miR-126 downregulates CXCL12 expression in intestinal epithelial cells to suppress the recruitment and function of macrophages and tumorigenesis in a murine model of colitis-associated colorectal cancer.
Tannins in Terminalia bellirica inhibits hepatocellular carcinoma growth via re-educating tumor-associated macrophages and restoring CD8(+)T cell function.
An improved cell line-derived xenograft humanized mouse model for evaluation of PD-1/PD-L1 blocker BMS202-induced immune responses in colorectal cancer.
Si-Wu-Tang ameliorates bile duct ligation-induced liver fibrosis via modulating immune environment.
Machine learning-based tumor-infiltrating immune cell-associated lncRNAs for predicting prognosis and immunotherapy response in patients with glioblastoma.
Identification of CD73 as a Novel Biomarker Encompassing the Tumor Microenvironment, Prognosis, and Therapeutic Responses in Various Cancers.
Programmed death ligand 1 and tumor-infiltrating CD8(+) T lymphocytes are associated with the clinical features in meningioma.
LRRC8A Is a Promising Prognostic Biomarker and Therapeutic Target for Pancreatic Adenocarcinoma.
CD4(+) T cells are required to improve the efficacy of CIK therapy in non-small cell lung cancer.
The Immunological Contribution of a Novel Metabolism-Related Signature to the Prognosis and Anti-Tumor Immunity in Cervical Cancer.
Single-cell transcriptomics links malignant T cells to the tumor immune landscape in cutaneous T cell lymphoma.
Polymeric indoximod based prodrug nanoparticles with doxorubicin entrapment for inducing immunogenic cell death and improving the immunotherapy of breast cancer.
Photosynthetic microorganisms coupled photodynamic therapy for enhanced antitumor immune effect.
The impact of neoadjuvant chemotherapy on the tumor microenvironment in advanced high-grade serous carcinoma.
CMTM6: increased circulating level and up-regulated expression in labial salivary glands in patients with primary Sjogren's syndrome.
Remodeling Chondroitin-6-Sulfate-Mediated Immune Exclusion Enhances Anti-PD-1 Response in Colorectal Cancer with Microsatellite Stability.
Salivary non-apoptotic tumoral microvesicles: A potential progressive marker in oral cancer patients.
Interleukin-10 induces expression of CD39 on CD8+T cells to potentiate anti-PD1 efficacy in EGFR-mutated non-small cell lung cancer.
SPI1 is a prognostic biomarker of immune infiltration and immunotherapy efficacy in clear cell renal cell carcinoma.
Association of MARCH7 with tumor progression and T-cell infiltration in esophageal cancer.
Neuropilin-1 is a valuable biomarker for predicting response of advanced non-small cell lung cancer patients to hypofractionated radiotherapy and PD-1 blockade.
Downregulation of PD-L1 and HLA-I in non-small cell lung cancer with ALK fusion.
SIGLEC15 amplifies immunosuppressive properties of tumor-associated macrophages in pancreatic cancer.
Paraspeckle Promotes Hepatocellular Carcinoma Immune Escape by Sequestering IFNGR1 mRNA.
ACSL4 Expression Is Associated With CD8+ T Cell Infiltration and Immune Response in Bladder Cancer.
A Novel Strategy Conjugating PD-L1 Polypeptide With Doxorubicin Alleviates Chemotherapeutic Resistance and Enhances Immune Response in Colon Cancer.
Clinical Relevance and Prognostic Value of the Neuronal Protein Neuroligin 2 in Breast Cancer.
Development of bispecific anti-c-Met/PD-1 diabodies for the treatment of solid tumors and the effect of c-Met binding affinity on efficacy.
Injectable shear-thinning polylysine hydrogels for localized immunotherapy of gastric cancer through repolarization of tumor-associated macrophages.
Hyperbaric oxygen treatment on keloid tumor immune gene expression.
Cancer-cell-biomimetic Upconversion nanoparticles combining chemo-photodynamic therapy and CD73 blockade for metastatic triple-negative breast cancer.
A novel mechanism of lung cancer inhibition by methionine enkephalin through remodeling the immune status of the tumor microenvironment.
CMTM6 expression in M2 macrophages is a potential predictor of PD-1/PD-L1 inhibitor response in colorectal cancer.
Dipeptidyl Peptidase (DPP)-4 Inhibitor Impairs the Outcomes of Patients with Type 2 Diabetes Mellitus After Curative Resection for Colorectal Cancer.
A multi-effective and long-acting immunotherapy through one single hydrogel based injection.
The impact of tobacco exposure on tumor microenvironment and prognosis in lung adenocarcinoma by integrative analysis of multi-omics data.
Tailoring Chemoimmunostimulant Bioscaffolds for Inhibiting Tumor Growth and Metastasis after Incomplete Microwave Ablation.
FABP4 deactivates NF-κB-IL1α pathway by ubiquitinating ATPB in tumor-associated macrophages and promotes neuroblastoma progression.
CD137 agonist induces gastric cancer cell apoptosis by enhancing the functions of CD8(+) T cells via NF-κB signaling.
Role of GLUT-1 in the Upregulation of PD-L1 Expression After Radiotherapy and Association of PD-L1 with Favourable Overall Survival in Hypopharyngeal Cancer.
Whole-Exome Sequencing Reveals New Potential Mutations Genes for Primary Mucosa-Associated Lymphoid Tissue Lymphoma Arising From the Kidney.
IDO1 Expression Increased After Neoadjuvant Therapy Predicts Poor Pathologic Response and Prognosis in Esophageal Squamous Cell Carcinoma.
An IL6-Adenosine Positive Feedback Loop between CD73(+) γδTregs and CAFs Promotes Tumor Progression in Human Breast Cancer.
The innate immune effector ISG12a promotes cancer immunity by suppressing the canonical Wnt/β-catenin signaling pathway.
Metformin changes the immune microenvironment of colorectal cancer in patients with type 2 diabetes mellitus.
A Comparison of Splenic Pathologic Change and Immune Function in HBV-Related Portal Hypertension and Chinese Budd-Chiari Syndrome Patients with Hypersplenism.
Single-Cell Transcriptome Analysis Reveals Intratumoral Heterogeneity in ccRCC, which Results in Different Clinical Outcomes.
NIR-Triggered Sequentially Responsive Nanocarriers Amplified Cascade Synergistic Effect of Chemo-Photodynamic Therapy with Inspired Antitumor Immunity.
Wang X, Bai Y, Wang B
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Journal of inflammation research 2024;17:1805-1820
Platinum-based neoadjuvant chemotherapy upregulates STING/IFN pathway expression and promotes TILs infiltration in NSCLC.
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Frontiers in oncology 2024;14:1346225
Frontiers in oncology 2024;14:1346225
Exploring the impact of PDGFD in osteosarcoma metastasis through single-cell sequencing analysis.
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Integrative analysis of the cuproptosis-related gene ATP7B in the prognosis and immune infiltration of IDH1 wild-type glioma.
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NDRG1 overcomes resistance to immunotherapy of pancreatic ductal adenocarcinoma through inhibiting ATG9A-dependent degradation of MHC-1.
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Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2024 Mar;73:101040
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Modified Biejia Jianwan decoction restrains PD-L1-mediated immune evasion through the HIF-1α/STAT3/NF-κB signaling pathway.
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Journal of ethnopharmacology 2024 Mar 25;322:117577
Journal of ethnopharmacology 2024 Mar 25;322:117577
WTAP regulates the production of reactive oxygen species, promotes malignant progression, and is closely related to the tumor microenvironment in glioblastoma.
Ji Q, Guo Y, Li Z, Zhang X
Aging 2024 Mar 25;16(6):5601-5617
Aging 2024 Mar 25;16(6):5601-5617
The construction of modular universal chimeric antigen receptor T (MU-CAR-T) cells by covalent linkage of allogeneic T cells and various antibody fragments.
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Molecular cancer 2024 Mar 11;23(1):53
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Pan-Cancer Single-Cell and Spatial-Resolved Profiling Reveals the Immunosuppressive Role of APOE+ Macrophages in Immune Checkpoint Inhibitor Therapy.
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GSK0660 enhances antitumor immunotherapy by reducing PD-L1 expression.
Khan B, Chen M, Wang H, Khan A, Hussain S, Shi J, Yang L, Hou Y
European journal of pharmacology 2024 Jun 5;972:176565
European journal of pharmacology 2024 Jun 5;972:176565
Distinctive multicellular immunosuppressive hubs confer different intervention strategies for left- and right-sided colon cancers.
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Cell reports. Medicine 2024 Jun 18;5(6):101589
Cell reports. Medicine 2024 Jun 18;5(6):101589
Transdermal delivery of Fn14 siRNA using a novel composite ionic liquid for treatment of psoriasis-like skin lesions.
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Journal of controlled release : official journal of the Controlled Release Society 2024 Jan;365:818-832
Journal of controlled release : official journal of the Controlled Release Society 2024 Jan;365:818-832
Gut microbiota modulate CD8(+) T cell immunity in gastric cancer through Butyrate/GPR109A/HOPX.
Yu X, Ou J, Wang L, Li Z, Ren Y, Xie L, Chen Z, Liang J, Shen G, Zou Z, Zhao C, Li G, Hu Y
Gut microbes 2024 Jan-Dec;16(1):2307542
Gut microbes 2024 Jan-Dec;16(1):2307542
Pumilio1 regulates NPM3/NPM1 axis to promote PD-L1-mediated immune escape in gastric cancer.
Wang H, Zhou Z, Zhang J, Hao T, Wang P, Wu P, Su R, Yang H, Deng G, Chen S, Gu L, He Y, Zeng L, Zhang C, Yin S
Cancer letters 2024 Jan 28;581:216498
Cancer letters 2024 Jan 28;581:216498
UPP1 promotes lung adenocarcinoma progression through the induction of an immunosuppressive microenvironment.
Li Y, Jiang M, Aye L, Luo L, Zhang Y, Xu F, Wei Y, Peng D, He X, Gu J, Yu X, Li G, Ge D, Lu C
Nature communications 2024 Feb 8;15(1):1200
Nature communications 2024 Feb 8;15(1):1200
Blockade of C5a receptor unleashes tumor-associated macrophage antitumor response and enhances CXCL9-dependent CD8(+) T cell activity.
Luan X, Lei T, Fang J, Liu X, Fu H, Li Y, Chu W, Jiang P, Tong C, Qi H, Fu Y
Molecular therapy : the journal of the American Society of Gene Therapy 2024 Feb 7;32(2):469-489
Molecular therapy : the journal of the American Society of Gene Therapy 2024 Feb 7;32(2):469-489
Nicotinamide metabolism face-off between macrophages and fibroblasts manipulates the microenvironment in gastric cancer.
Jiang Y, Wang Y, Chen G, Sun F, Wu Q, Huang Q, Zeng D, Qiu W, Wang J, Yao Z, Liang B, Li S, Wu J, Huang N, Wang Y, Chen J, Zhai X, Huang L, Xu B, Yamamoto M, Tsukamoto T, Nomura S, Liao W, Shi M
Cell metabolism 2024 Aug 6;36(8):1806-1822.e11
Cell metabolism 2024 Aug 6;36(8):1806-1822.e11
The prognostic value of CD8(+) CTLs, CD163(+) TAMs, and PDL1 expression in the tumor microenvironment of primary central nervous system lymphoma.
Jin Q, Jiang H, Yue N, Zhang L, Li C, Dong C, Zeng P, Yue L, Wu C
Leukemia & lymphoma 2024 Apr;65(4):472-480
Leukemia & lymphoma 2024 Apr;65(4):472-480
Immune characteristics associated with lymph node metastasis in early-stage NSCLC.
Zhang Z, Li L, Gao Y, Xiao X, Ji L, Zhou Z, Jiang J, Liu S, An J, Deng P, Du N, Li P, Xia X, Hu C, Li M
Cellular oncology (Dordrecht, Netherlands) 2024 Apr;47(2):447-461
Cellular oncology (Dordrecht, Netherlands) 2024 Apr;47(2):447-461
Tumor-activated IL-2 mRNA delivered by lipid nanoparticles for cancer immunotherapy.
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Journal of controlled release : official journal of the Controlled Release Society 2024 Apr;368:663-675
Journal of controlled release : official journal of the Controlled Release Society 2024 Apr;368:663-675
Mn-Anti-CTLA4-CREKA-Sericin Nanotheragnostics for Enhanced Magnetic Resonance Imaging and Tumor Immunotherapy.
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Small (Weinheim an der Bergstrasse, Germany) 2024 Apr;20(15):e2306912
Small (Weinheim an der Bergstrasse, Germany) 2024 Apr;20(15):e2306912
Glycyrrhetinic acid inhibits non-small cell lung cancer via promotion of Prdx6- and caspase-3-mediated mitochondrial apoptosis.
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Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Apr;173:116304
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Apr;173:116304
Hippo-signaling-controlled MHC class I antigen processing and presentation pathway potentiates antitumor immunity.
Peng L, Zhou L, Li H, Zhang X, Li S, Wang K, Yang M, Ma X, Zhang D, Xiang S, Duan Y, Wang T, Sun C, Wang C, Lu D, Qian M, Wang Z
Cell reports 2024 Apr 23;43(4):114003
Cell reports 2024 Apr 23;43(4):114003
Diaphorobacter nitroreducens synergize with oxaliplatin to reduce tumor burden in mice with lung adenocarcinoma.
Ni Y, Li R, Shen X, Yi D, Ren Y, Wang F, Geng Y, You Q
mSystems 2024 Apr 16;9(4):e0132323
mSystems 2024 Apr 16;9(4):e0132323
Scutellarin activates IDH1 to exert antitumor effects in hepatocellular carcinoma progression.
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Cell death & disease 2024 Apr 15;15(4):267
Cell death & disease 2024 Apr 15;15(4):267
ISG15 is a potential therapeutic target for osteosarcoma: a comprehensive analysis based on bioinformatics and in vitro experiments.
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American journal of translational research 2023;15(2):817-833
American journal of translational research 2023;15(2):817-833
Tumor-secreted lactate contributes to an immunosuppressive microenvironment and affects CD8 T-cell infiltration in glioblastoma.
Wang Z, Dai Z, Zhang H, Liang X, Zhang X, Wen Z, Luo P, Zhang J, Liu Z, Zhang M, Cheng Q
Frontiers in immunology 2023;14:894853
Frontiers in immunology 2023;14:894853
FANCI serve as a prognostic biomarker correlated with immune infiltrates in skin cutaneous melanoma.
Cai Z, Duan Y, Li W, Liu Z, Gong Z, Hong S, He X, Xuanyuan X, Chen Y, Bi X, Wang W
Frontiers in immunology 2023;14:1295831
Frontiers in immunology 2023;14:1295831
A novel prognostic signatures based on metastasis- and immune-related gene pairs for colorectal cancer.
Pan B, Yue Y, Ding W, Sun L, Xu M, Wang S
Frontiers in immunology 2023;14:1161382
Frontiers in immunology 2023;14:1161382
PD-L1 and tumor-infiltrating CD8(+) lymphocytes are correlated with clinical characteristics in pediatric and adolescent pituitary adenomas.
Shi M, Song Y, Zhang Y, Li L, Yu J, Hou A, Han S
Frontiers in endocrinology 2023;14:1151714
Frontiers in endocrinology 2023;14:1151714
LRPPRC facilitates tumor progression and immune evasion through upregulation of m(6)A modification of PD-L1 mRNA in hepatocellular carcinoma.
Wang H, Tang A, Cui Y, Gong H, Li H
Frontiers in immunology 2023;14:1144774
Frontiers in immunology 2023;14:1144774
Establishment and validation of an immune infiltration predictive model for ovarian cancer.
Song Z, Zhang J, Sun Y, Jiang Z, Liu X
BMC medical genomics 2023 Sep 28;16(1):227
BMC medical genomics 2023 Sep 28;16(1):227
Single-cell and bulk sequencing analyses reveal the immune suppressive role of PTPN6 in glioblastoma.
Zhang X, Chen J, Zhang M, Liu S, Wang T, Wu T, Li B, Zhao S, Wang H, Li L, Wang C, Huang L
Aging 2023 Sep 21;15(18):9822-9841
Aging 2023 Sep 21;15(18):9822-9841
Ki67-targeted oncolytic adenovirus expressing IL-15 improves intratumoral T cell infiltration and PD-L1 expression in glioblastoma.
Zhang Q, Zhang J, Tian Y, Wang J, Jin G, Liu F
Virology 2023 Oct;587:109885
Virology 2023 Oct;587:109885
METTL3 inhibition induced by M2 macrophage-derived extracellular vesicles drives anti-PD-1 therapy resistance via M6A-CD70-mediated immune suppression in thyroid cancer.
Ning J, Hou X, Hao J, Zhang W, Shi Y, Huang Y, Ruan X, Zheng X, Gao M
Cell death and differentiation 2023 Oct;30(10):2265-2279
Cell death and differentiation 2023 Oct;30(10):2265-2279
Targeting TNFAIP2 induces immunogenic cell death and sensitizes glioblastoma multiforme to anti-PD-1 therapy.
Hou C, Shi S, Gao M, Ji J, Ma C, Wang T, Chen T, Liu Y, Zhong J, Zheng Y, Ye J, Ke Y
Journal of neuro-oncology 2023 Oct;165(1):79-90
Journal of neuro-oncology 2023 Oct;165(1):79-90
A Booster for Radiofrequency Ablation: Advanced Adjuvant Therapy via In Situ Nanovaccine Synergized with Anti-programmed Death Ligand 1 Immunotherapy for Systemically Constraining Hepatocellular Carcinoma.
Tian Z, Hu Q, Sun Z, Wang N, He H, Tang Z, Chen W
ACS nano 2023 Oct 10;17(19):19441-19458
ACS nano 2023 Oct 10;17(19):19441-19458
Deubiquitinase inhibitor PR-619 potentiates colon cancer immunotherapy by inducing ferroptosis.
Wu J, Liu C, Wang T, Liu H, Wei B
Immunology 2023 Nov;170(3):439-451
Immunology 2023 Nov;170(3):439-451
Mesothelin-targeted CAR-T therapy combined with irinotecan for the treatment of solid cancer.
Zhu Y, Zuo D, Wang K, Lan S, He H, Chen L, Chen X, Feng M
Journal of cancer research and clinical oncology 2023 Nov;149(16):15027-15038
Journal of cancer research and clinical oncology 2023 Nov;149(16):15027-15038
Engineering high-affinity dual targeting cellular nanovesicles for optimised cancer immunotherapy.
Zhang L, Zhao X, Niu Y, Ma X, Yuan W, Ma J
Journal of extracellular vesicles 2023 Nov;12(11):e12379
Journal of extracellular vesicles 2023 Nov;12(11):e12379
Low-dose radiotherapy combined with dual PD-L1 and VEGFA blockade elicits antitumor response in hepatocellular carcinoma mediated by activated intratumoral CD8(+) exhausted-like T cells.
Li S, Li K, Wang K, Yu H, Wang X, Shi M, Liang Z, Yang Z, Hu Y, Li Y, Liu W, Li H, Cheng S, Ye L, Yang Y
Nature communications 2023 Nov 24;14(1):7709
Nature communications 2023 Nov 24;14(1):7709
TWEAK and Fn14 are overexpressed in immune-mediated necrotizing myopathy: implications for muscle damage and repair.
Yang M, Ge H, Ji S, Li Y, Xu L, Bi Z, Bu B
Rheumatology (Oxford, England) 2023 Nov 2;62(11):3732-3741
Rheumatology (Oxford, England) 2023 Nov 2;62(11):3732-3741
FAM171B stabilizes vimentin and enhances CCL2-mediated TAM infiltration to promote bladder cancer progression.
Hu WM, Li M, Ning JZ, Tang YQ, Song TB, Li LZ, Zou F, Cheng F, Yu WM
Journal of experimental & clinical cancer research : CR 2023 Nov 2;42(1):290
Journal of experimental & clinical cancer research : CR 2023 Nov 2;42(1):290
Combination of novel oncolytic herpesvirus with paclitaxel as an efficient strategy for breast cancer therapy.
Deng X, Shen Y, Yi M, Zhang C, Zhao B, Zhong G, WeiyangLou, Xue D, Leng Q, Ding J, Zhao R, Jia W, Dong C, Dai Z
Journal of medical virology 2023 May;95(5):e28768
Journal of medical virology 2023 May;95(5):e28768
Exploration of (68)Ga-labelled prostate-specific membrane antigen-11 PET/CT parameters for identifying PBRM1 status in primary clear cell renal cell carcinoma.
Wang B, Deng Y, Xu Q, Gao J, Shen H, He X, Ding Q, Wang F, Guo H
Clinical radiology 2023 May;78(5):e417-e424
Clinical radiology 2023 May;78(5):e417-e424
Exosomal PD‑L1 promotes the formation of an immunosuppressive microenvironment in gastric diffuse large B‑cell lymphoma.
Zeng H, Wang J, Xu B, Deng H, Peng M, Deng R, Shang S, Hu Q, Li J, Lin J, Zhu H, Li Y, Zuo C
Oncology reports 2023 May;49(5)
Oncology reports 2023 May;49(5)
High baseline tumor burden-associated macrophages promote an immunosuppressive microenvironment and reduce the efficacy of immune checkpoint inhibitors through the IGFBP2-STAT3-PD-L1 pathway.
Wen Z, Sun H, Zhang Z, Zheng Y, Zheng S, Bin J, Liao Y, Shi M, Zhou R, Liao W
Cancer communications (London, England) 2023 May;43(5):562-581
Cancer communications (London, England) 2023 May;43(5):562-581
Prognostic value of CD8-to-EGFR ratio in salivary microvesicles of patients with oral squamous cell carcinoma.
Man QW, Li RF, Zhong NN, Liu B
Oral diseases 2023 May;29(4):1480-1486
Oral diseases 2023 May;29(4):1480-1486
GBP2 promotes clear cell renal cell carcinoma progression through immune infiltration and regulation of PD‑L1 expression via STAT1 signaling.
Ye S, Li S, Qin L, Zheng W, Liu B, Li X, Ren Z, Zhao H, Hu X, Ye N, Li G
Oncology reports 2023 Mar;49(3)
Oncology reports 2023 Mar;49(3)
Oncogenic epidermal growth factor receptor signal-induced histone deacetylation suppresses chemokine gene expression in human lung adenocarcinoma.
Sumimoto H, Takano A, Igarashi T, Hanaoka J, Teramoto K, Daigo Y
Scientific reports 2023 Mar 29;13(1):5087
Scientific reports 2023 Mar 29;13(1):5087
Anti-signal recognition particle positive necrotizing myopathy-sjogren's syndrome overlap syndrome: a descriptive study on clinical and myopathology features.
Xu L, Yang MG, Hu L, Gao H, Ji S
BMC musculoskeletal disorders 2023 Mar 23;24(1):219
BMC musculoskeletal disorders 2023 Mar 23;24(1):219
PYCR1 promotes the malignant progression of lung cancer through the JAK-STAT3 signaling pathway via PRODH-dependent glutamine synthesize.
Zhang L, Zhao X, Wang E, Yang Y, Hu L, Xu H, Zhang B
Translational oncology 2023 Jun;32:101667
Translational oncology 2023 Jun;32:101667
An integrated bioinformatic investigation of focal adhesion-related genes in glioma followed by preliminary validation of COL1A2 in tumorigenesis.
Yao G, Deng L, Long X, Zhou Y, Zhou X
Aging 2023 Jun 22;15(13):6225-6254
Aging 2023 Jun 22;15(13):6225-6254
Optogenetic engineered umbilical cord MSC-derived exosomes for remodeling of the immune microenvironment in diabetic wounds and the promotion of tissue repair.
Zhao X, Fu L, Zou H, He Y, Pan Y, Ye L, Huang Y, Fan W, Zhang J, Ma Y, Chen J, Zhu M, Zhang C, Cai Y, Mou X
Journal of nanobiotechnology 2023 Jun 2;21(1):176
Journal of nanobiotechnology 2023 Jun 2;21(1):176
STAT4, a potential predictor of prognosis, promotes CD8 T‑cell infiltration in ovarian serous carcinoma by inducing CCL5 secretion.
Wang W, Liu S, Lu F, Yang B, Zhuang X, Yin J, Chen G, Sun C
Oncology reports 2023 Jul;50(1)
Oncology reports 2023 Jul;50(1)
An inflammation-associated ferroptosis signature optimizes the diagnosis, prognosis evaluation and immunotherapy options in hepatocellular carcinoma.
Ruan WY, Zhang L, Lei S, Zeng ZR, Yang YS, Cao WP, Hao QY, Lu M, Tian XB, Peng PL
Journal of cellular and molecular medicine 2023 Jul;27(13):1820-1835
Journal of cellular and molecular medicine 2023 Jul;27(13):1820-1835
Inhibition of FGFR3 upregulates MHC-I and PD-L1 via TLR3/NF-kB pathway in muscle-invasive bladder cancer.
Wu W, Chen L, Jia G, Tang Q, Han B, Xia S, Jiang Q, Liu H
Cancer medicine 2023 Jul;12(14):15676-15690
Cancer medicine 2023 Jul;12(14):15676-15690
Intra-tumoral infiltration of adipocyte facilitates the activation of antitumor immune response in pancreatic ductal adenocarcinoma.
Liu X, Liu J, Xu J, Zhang B, Wei M, Li J, Xu H, Yu X, Wang W, Shi S
Translational oncology 2023 Jan;27:101561
Translational oncology 2023 Jan;27:101561
Virulence factors and mechanisms of paediatric pneumonia caused by Enterococcus faecalis.
Tian Z, Khan AI, Rehman AU, Deng T, Ma C, Wang L
Gut pathogens 2023 Jan 9;15(1):2
Gut pathogens 2023 Jan 9;15(1):2
Inhibition of Checkpoint Kinase 1 (CHK1) Upregulates Interferon Regulatory Factor 1 (IRF1) to Promote Apoptosis and Activate Anti-Tumor Immunity via MICA in Hepatocellular Carcinoma (HCC).
Li X, Huang J, Wu Q, Du Q, Wang Y, Huang Y, Cai X, Geller DA, Yan Y
Cancers 2023 Jan 30;15(3)
Cancers 2023 Jan 30;15(3)
Expression of glucose transporter-1 in follicular lymphoma affected tumor-infiltrating immunocytes and was related to progression of disease within 24 months.
Deng Y, Ma J, Zhao S, Yang M, Sun Y, Zhang Q
Translational oncology 2023 Feb;28:101614
Translational oncology 2023 Feb;28:101614
The PD-L1 Expression and Tumor-Infiltrating Immune Cells Predict an Unfavorable Prognosis in Pancreatic Ductal Adenocarcinoma and Adenosquamous Carcinoma.
Zhang Z, Xiong Q, Xu Y, Cai X, Zhang L, Zhu Q
Journal of clinical medicine 2023 Feb 9;12(4)
Journal of clinical medicine 2023 Feb 9;12(4)
HNRNPL induced circFAM13B increased bladder cancer immunotherapy sensitivity via inhibiting glycolysis through IGF2BP1/PKM2 pathway.
Lv J, Li K, Yu H, Han J, Zhuang J, Yu R, Cheng Y, Song Q, Bai K, Cao Q, Yang H, Yang X, Lu Q
Journal of experimental & clinical cancer research : CR 2023 Feb 6;42(1):41
Journal of experimental & clinical cancer research : CR 2023 Feb 6;42(1):41
HRS Regulates Small Extracellular Vesicle PD-L1 Secretion and Is Associated with Anti-PD-1 Treatment Efficacy.
Xiao BL, Wang XL, Xia HF, Zhang LZ, Wang KM, Chen ZK, Zhong YH, Jiang HG, Zhou FX, Wang W, Chen GL, Chen G
Cancer immunology research 2023 Feb 3;11(2):228-240
Cancer immunology research 2023 Feb 3;11(2):228-240
Apoptotic tumor cell-derived microparticles loading Napabucasin inhibit CSCs and synergistic immune therapy.
Jing B, Guo F, An R, Gao Y, Li Y, Xie Y, Wang J, Chen Y, Li H, Gao T, Jin Q, Zhang L, Xie M
Journal of nanobiotechnology 2023 Feb 2;21(1):37
Journal of nanobiotechnology 2023 Feb 2;21(1):37
Proteomic and single-cell landscape reveals novel pathogenic mechanisms of HBV-infected intrahepatic cholangiocarcinoma.
Shen Y, Xu S, Ye C, Li Q, Chen R, Wu W, Jiang Q, Jia Y, Zhang X, Fan L, Fu W, Jiang M, Chen J, Timko MP, Zhao P, Ruan J
iScience 2023 Feb 17;26(2):106003
iScience 2023 Feb 17;26(2):106003
Behind the Indolent Facade: Uncovering the Molecular Features and Malignancy Potential in Lung Minimally Invasive Adenocarcinoma by Single-Cell Transcriptomics.
Zhang X, Liang B, Huang Y, Meng H, Li Z, Du J, Zhou L, Zhong Y, Wang B, Lin X, Yu G, Chen X, Lu W, Chen ZS, Yang X, Huang Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Dec;10(36):e2303753
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Dec;10(36):e2303753
PPARγ agonist inhibits c-Myc-mediated colorectal cancer tumor immune escape.
Xu L, Che S, Chen H, Liu Q, Shi J, Jin J, Hou Y
Journal of cellular biochemistry 2023 Aug;124(8):1145-1154
Journal of cellular biochemistry 2023 Aug;124(8):1145-1154
Single cell transcriptomic analyses implicate an immunosuppressive tumor microenvironment in pancreatic cancer liver metastasis.
Zhang S, Fang W, Zhou S, Zhu D, Chen R, Gao X, Li Z, Fu Y, Zhang Y, Yang F, Zhao J, Wu H, Wang P, Shen Y, Shen S, Xu G, Wang L, Yan C, Zou X, Chen D, Lv Y
Nature communications 2023 Aug 23;14(1):5123
Nature communications 2023 Aug 23;14(1):5123
Single-cell dissection of cervical cancer reveals key subsets of the tumor immune microenvironment.
Cao G, Yue J, Ruan Y, Han Y, Zhi Y, Lu J, Liu M, Xu X, Wang J, Gu Q, Wen X, Gao J, Zhang Q, Kang J, Wang C, Li F
The EMBO journal 2023 Aug 15;42(16):e110757
The EMBO journal 2023 Aug 15;42(16):e110757
CT-based radiomics signature to predict CD8+ tumor infiltrating lymphocytes in non-small-cell lung cancer.
Chen Y, Xu T, Jiang C, You S, Cheng Z, Gong J
Acta radiologica (Stockholm, Sweden : 1987) 2023 Apr;64(4):1390-1399
Acta radiologica (Stockholm, Sweden : 1987) 2023 Apr;64(4):1390-1399
Regulation of CD8(+) T cells infiltration and immunotherapy by circMGA/HNRNPL complex in bladder cancer.
Sun J, Zhang H, Wei W, Xiao X, Huang C, Wang L, Zhong H, Jiang Y, Zheng F, Yang H, Jiang G, Zhang X
Oncogene 2023 Apr;42(15):1247-1262
Oncogene 2023 Apr;42(15):1247-1262
MAX transcriptionally enhances PD-L1 to inhibit CD8+ T cell-mediated killing of lung adenocarcinoma cells.
Huang D, Wang X, Qian Y, Wu J, Chen B, Zhang D, Dong F, Li Y
Cellular immunology 2023 Apr;386:104706
Cellular immunology 2023 Apr;386:104706
Characterization of myeloid signature genes for predicting prognosis and immune landscape in Ewing sarcoma.
Zhang Z, Shi Y, Zhu Z, Fu J, Liu D, Liu X, Dang J, Tao H, Fan H
Cancer science 2023 Apr;114(4):1240-1255
Cancer science 2023 Apr;114(4):1240-1255
Self-Assembly Catalase Nanocomplex Conveyed by Bacterial Vesicles for Oxygenated Photodynamic Therapy and Tumor Immunotherapy.
Zhang J, Li Z, Liu L, Li L, Zhang L, Wang Y, Zhao J
International journal of nanomedicine 2022;17:1971-1985
International journal of nanomedicine 2022;17:1971-1985
CLEC1B is a Promising Prognostic Biomarker and Correlated with Immune Infiltration in Hepatocellular Carcinoma.
Liang X, Song F, Fang W, Zhang Y, Feng Z, Chen Z, Han L, Chen Z
International journal of general medicine 2022;15:5661-5672
International journal of general medicine 2022;15:5661-5672
A Comparison for Type 2 Cytokines and Lesional Inflammatory Infiltrations in Bullous Pemphigoid and Atopic Dermatitis.
Hu YQ, Zhang JZ
Clinical, cosmetic and investigational dermatology 2022;15:2313-2321
Clinical, cosmetic and investigational dermatology 2022;15:2313-2321
Identification of a novel immune gene panel in tongue squamous cell carcinoma.
Sun J, Guo F, Tang Q, Chen G, Peng J, Shen Y, Zhang J, Hu J, Yang C
American journal of translational research 2022;14(5):2801-2824
American journal of translational research 2022;14(5):2801-2824
Single-cell sequencing reveals effects of chemotherapy on the immune landscape and TCR/BCR clonal expansion in a relapsed ovarian cancer patient.
Ren Y, Li R, Feng H, Xie J, Gao L, Chu S, Li Y, Meng F, Ning Y
Frontiers in immunology 2022;13:985187
Frontiers in immunology 2022;13:985187
Identification of ST3GAL5 as a prognostic biomarker correlating with CD8(+) T cell exhaustion in clear cell renal cell carcinoma.
Liu J, Li M, Wu J, Qi Q, Li Y, Wang S, Liang S, Zhang Y, Zhu Z, Huang R, Yan J, Zhu R
Frontiers in immunology 2022;13:979605
Frontiers in immunology 2022;13:979605
CEP192 is a novel prognostic marker and correlates with the immune microenvironment in hepatocellular carcinoma.
Liu Y, Liang W, Chang Y, He Z, Wu M, Zheng H, Ke X, Lv M, Liu Q, Liu Q, Tang W, Huang Q, Lu Y, He M, Yang Q, Mo C, Wang J, Peng K, Min Z, Su H, Chen J
Frontiers in immunology 2022;13:950884
Frontiers in immunology 2022;13:950884
A Study on the Radiosensitivity of Radiation-Induced Lung Injury at the Acute Phase Based on Single-Cell Transcriptomics.
Ma L, Ye Y, Lu H, Xing Y, Zhao Z, Quan C, Jia Z, Lu Y, Li Y, Zhou G
Frontiers in immunology 2022;13:941976
Frontiers in immunology 2022;13:941976
Single-cell RNA sequencing reveals distinct immunology profiles in human keloid.
Feng C, Shan M, Xia Y, Zheng Z, He K, Wei Y, Song K, Meng T, Liu H, Hao Y, Liang Z, Wang Y, Huang Y
Frontiers in immunology 2022;13:940645
Frontiers in immunology 2022;13:940645
Identify the immune characteristics and immunotherapy value of CD93 in the pan-cancer based on the public data sets.
Guo A, Zhang J, Tian Y, Peng Y, Luo P, Zhang J, Liu Z, Wu W, Zhang H, Cheng Q
Frontiers in immunology 2022;13:907182
Frontiers in immunology 2022;13:907182
Transmembrane Protein 170B is a Prognostic Biomarker and Associated With Immune Infiltrates in Pancreatic Adenocarcinoma.
Zhang Z, Shang J, Dai Z, Yao Y, Shi Y, Zhong D, Liang Y, Lai C, Yang Q, Feng T, Huang X
Frontiers in genetics 2022;13:848391
Frontiers in genetics 2022;13:848391
A Pan-Cancer Analysis Reveals CLEC5A as a Biomarker for Cancer Immunity and Prognosis.
Chen R, Wu W, Chen SY, Liu ZZ, Wen ZP, Yu J, Zhang LB, Liu Z, Zhang J, Luo P, Zeng WJ, Cheng Q
Frontiers in immunology 2022;13:831542
Frontiers in immunology 2022;13:831542
A novel ganglioside-related risk signature can reveal the distinct immune landscape of neuroblastoma and predict the immunotherapeutic response.
Yang J, Han L, Sha Y, Jin Y, Li Z, Gong B, Li J, Liu Y, Wang Y, Zhao Q
Frontiers in immunology 2022;13:1061814
Frontiers in immunology 2022;13:1061814
Identification and experimental validation of a tumor-infiltrating lymphocytes-related long noncoding RNA signature for prognosis of clear cell renal cell carcinoma.
Deng Y, Guo K, Tang Z, Feng Y, Cai S, Ye J, Xi Y, Li J, Liu R, Cai C, Tan Z, Zhang Y, Han Z, Zeng G, Zhong W
Frontiers in immunology 2022;13:1046790
Frontiers in immunology 2022;13:1046790
A pan-cancer and single-cell sequencing analysis of CD161, a promising onco-immunological biomarker in tumor microenvironment and immunotherapy.
Li H, Zhou K, Wang K, Cao H, Wu W, Wang Z, Dai Z, Chen S, Peng Y, Xiao G, Luo P, Zhang J, Liu Z, Cheng Q, Zhang H
Frontiers in immunology 2022;13:1040289
Frontiers in immunology 2022;13:1040289
A specific immune signature for predicting the prognosis of glioma patients with IDH1-mutation and guiding immune checkpoint blockade therapy.
Zeng Z, Hu C, Ruan W, Zhang J, Lei S, Yang Y, Peng P, Pan F, Chen T
Frontiers in immunology 2022;13:1001381
Frontiers in immunology 2022;13:1001381
Machine learning-based identification of tumor-infiltrating immune cell-associated lncRNAs for improving outcomes and immunotherapy responses in patients with low-grade glioma.
Zhang N, Zhang H, Wu W, Zhou R, Li S, Wang Z, Dai Z, Zhang L, Liu F, Liu Z, Zhang J, Luo P, Liu Z, Cheng Q
Theranostics 2022;12(13):5931-5948
Theranostics 2022;12(13):5931-5948
Label-free LC-MS/MS proteomics analyses reveal CLIC1 as a predictive biomarker for bladder cancer staging and prognosis.
Wang W, Huang G, Lin H, Ren L, Fu L, Mao X
Frontiers in oncology 2022;12:1102392
Frontiers in oncology 2022;12:1102392
Screening of an individualized treatment strategy for an advanced gallbladder cancer using patient-derived tumor xenograft and organoid models.
Tan D, An J, Gong M, Wang H, Li H, Meng H, Zhang C, Zhao Y, Ge X, Shi C
Frontiers in oncology 2022;12:1043479
Frontiers in oncology 2022;12:1043479
Oncolytic adenovirus with MUC16-BiTE shows enhanced antitumor immune response by reversing the tumor microenvironment in PDX model of ovarian cancer.
Wang Q, Ma X, Wu H, Zhao C, Chen J, Li R, Yan S, Li Y, Zhang Q, Song K, Yuan C, Kong B
Oncoimmunology 2022;11(1):2096362
Oncoimmunology 2022;11(1):2096362
Identify the Prognostic and Immune Profile of VSIR in the Tumor Microenvironment: A Pan-Cancer Analysis.
Liu Y, Zhang J, Wang Z, Zhang X, Dai Z, Wu W, Zhang N, Liu Z, Zhang J, Luo P, Wen Z, Yu J, Zhang H, Yang T, Cheng Q
Frontiers in cell and developmental biology 2022;10:821649
Frontiers in cell and developmental biology 2022;10:821649
Immunohistochemical analysis of PD-L1 and tumor-infiltrating immune cells expression in the tumor microenvironment of primary signet ring cell carcinoma of the prostate.
Teng QL, Yang XR, Wen S, Dai ZH, Wang HL, Liu TQ, Wang L, Fan B, Liu ZY
Asian journal of andrology 2022 Sep-Oct;24(5):525-532
Asian journal of andrology 2022 Sep-Oct;24(5):525-532
Sphingosine kinase 1 promotes tumor immune evasion by regulating the MTA3-PD-L1 axis.
Lau P, Zhang G, Zhao S, Liang L, Zhang H, Zhou G, Hung MC, Chen X, Liu H
Cellular & molecular immunology 2022 Oct;19(10):1153-1167
Cellular & molecular immunology 2022 Oct;19(10):1153-1167
miR-126 downregulates CXCL12 expression in intestinal epithelial cells to suppress the recruitment and function of macrophages and tumorigenesis in a murine model of colitis-associated colorectal cancer.
Wu S, Yuan W, Luo W, Nie K, Wu X, Meng X, Shen Z, Wang X
Molecular oncology 2022 Oct;16(19):3465-3489
Molecular oncology 2022 Oct;16(19):3465-3489
Tannins in Terminalia bellirica inhibits hepatocellular carcinoma growth via re-educating tumor-associated macrophages and restoring CD8(+)T cell function.
Chang Z, Zhang Q, Hu Q, Liu Y, Zhang L, Liu R
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Oct;154:113543
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Oct;154:113543
An improved cell line-derived xenograft humanized mouse model for evaluation of PD-1/PD-L1 blocker BMS202-induced immune responses in colorectal cancer.
Shang P, Yu L, Cao S, Guo C, Zhang W
Acta biochimica et biophysica Sinica 2022 Oct 25;54(10):1497-1506
Acta biochimica et biophysica Sinica 2022 Oct 25;54(10):1497-1506
Si-Wu-Tang ameliorates bile duct ligation-induced liver fibrosis via modulating immune environment.
Ma Z, Xue X, Bai J, Cai Y, Jin X, Jia K, Ding M, Lyu X, Li X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Nov;155:113834
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Nov;155:113834
Machine learning-based tumor-infiltrating immune cell-associated lncRNAs for predicting prognosis and immunotherapy response in patients with glioblastoma.
Zhang H, Zhang N, Wu W, Zhou R, Li S, Wang Z, Dai Z, Zhang L, Liu Z, Zhang J, Luo P, Liu Z, Cheng Q
Briefings in bioinformatics 2022 Nov 19;23(6)
Briefings in bioinformatics 2022 Nov 19;23(6)
Identification of CD73 as a Novel Biomarker Encompassing the Tumor Microenvironment, Prognosis, and Therapeutic Responses in Various Cancers.
Tang K, Zhang J, Cao H, Xiao G, Wang Z, Zhang X, Zhang N, Wu W, Zhang H, Wang Q, Xu H, Cheng Q
Cancers 2022 Nov 17;14(22)
Cancers 2022 Nov 17;14(22)
Programmed death ligand 1 and tumor-infiltrating CD8(+) T lymphocytes are associated with the clinical features in meningioma.
Zhang Y, Wang X, Shi M, Song Y, Yu J, Han S
BMC cancer 2022 Nov 12;22(1):1171
BMC cancer 2022 Nov 12;22(1):1171
LRRC8A Is a Promising Prognostic Biomarker and Therapeutic Target for Pancreatic Adenocarcinoma.
Xu R, Hu Y, Xie Q, Zhang C, Zhao Y, Zhang H, Shi H, Wang X, Shi C
Cancers 2022 Nov 10;14(22)
Cancers 2022 Nov 10;14(22)
CD4(+) T cells are required to improve the efficacy of CIK therapy in non-small cell lung cancer.
Liu S, Meng Y, Liu L, Lv Y, Yu W, Liu T, Wang L, Mu D, Zhou Q, Liu M, Ren Y, Zhang D, Li B, Sun Q, Ren X
Cell death & disease 2022 May 6;13(5):441
Cell death & disease 2022 May 6;13(5):441
The Immunological Contribution of a Novel Metabolism-Related Signature to the Prognosis and Anti-Tumor Immunity in Cervical Cancer.
Yu S, Li X, Ma M, Yang R, Zhang J, Wu S
Cancers 2022 May 13;14(10)
Cancers 2022 May 13;14(10)
Single-cell transcriptomics links malignant T cells to the tumor immune landscape in cutaneous T cell lymphoma.
Liu X, Jin S, Hu S, Li R, Pan H, Liu Y, Lai P, Xu D, Sun J, Liu Z, Gao Y, Zhao Y, Liu F, Xiao Y, Li Y, Wen Y, Chen Z, Xu B, Lin Y, Ran M, Li Q, Yang S, Li H, Tu P, Haniffa M, Teichmann SA, Bai F, Wang Y
Nature communications 2022 Mar 3;13(1):1158
Nature communications 2022 Mar 3;13(1):1158
Polymeric indoximod based prodrug nanoparticles with doxorubicin entrapment for inducing immunogenic cell death and improving the immunotherapy of breast cancer.
Zang X, Song J, Yi X, Piyu J
Journal of materials chemistry. B 2022 Mar 23;10(12):2019-2027
Journal of materials chemistry. B 2022 Mar 23;10(12):2019-2027
Photosynthetic microorganisms coupled photodynamic therapy for enhanced antitumor immune effect.
Wang H, Liu H, Guo Y, Zai W, Li X, Xiong W, Zhao X, Yao Y, Hu Y, Zou Z, Wu J
Bioactive materials 2022 Jun;12:97-106
Bioactive materials 2022 Jun;12:97-106
The impact of neoadjuvant chemotherapy on the tumor microenvironment in advanced high-grade serous carcinoma.
Shen Y, Ren Y, Chen K, Cen Y, Zhang B, Lu W, Xu J
Oncogenesis 2022 Jul 30;11(1):43
Oncogenesis 2022 Jul 30;11(1):43
CMTM6: increased circulating level and up-regulated expression in labial salivary glands in patients with primary Sjogren's syndrome.
Qian S, Xu J, Zhao S, Yang P, Yang C
Clinical and experimental immunology 2022 Jan 28;207(1):65-71
Clinical and experimental immunology 2022 Jan 28;207(1):65-71
Remodeling Chondroitin-6-Sulfate-Mediated Immune Exclusion Enhances Anti-PD-1 Response in Colorectal Cancer with Microsatellite Stability.
Wu Q, Huang Q, Jiang Y, Sun F, Liang B, Wang J, Hu X, Sun M, Ma Z, Shi Y, Liang Y, Tan Y, Zeng D, Yao F, Xu X, Yao Z, Li S, Rong X, Huang N, Sun L, Liao W, Shi M
Cancer immunology research 2022 Feb;10(2):182-199
Cancer immunology research 2022 Feb;10(2):182-199
Salivary non-apoptotic tumoral microvesicles: A potential progressive marker in oral cancer patients.
Man QW, Li RF, Bu LL, Zhao Y, Liu B
Journal of cellular and molecular medicine 2022 Dec;26(24):5955-5965
Journal of cellular and molecular medicine 2022 Dec;26(24):5955-5965
Interleukin-10 induces expression of CD39 on CD8+T cells to potentiate anti-PD1 efficacy in EGFR-mutated non-small cell lung cancer.
Qiao M, Zhou F, Liu X, Jiang T, Wang H, Jia Y, Li X, Zhao C, Cheng L, Chen X, Ren S, Liu H, Zhou C
Journal for immunotherapy of cancer 2022 Dec;10(12)
Journal for immunotherapy of cancer 2022 Dec;10(12)
SPI1 is a prognostic biomarker of immune infiltration and immunotherapy efficacy in clear cell renal cell carcinoma.
Feng H, Wang T, Ye J, Yang Y, Huang X, Lai D, Lv Z, Huang Y, Zhang X
Discover oncology 2022 Dec 7;13(1):134
Discover oncology 2022 Dec 7;13(1):134
Association of MARCH7 with tumor progression and T-cell infiltration in esophageal cancer.
Singh S, Bano A, Saraya A, Das P, Sharma R
Medical oncology (Northwood, London, England) 2022 Dec 30;40(1):67
Medical oncology (Northwood, London, England) 2022 Dec 30;40(1):67
Neuropilin-1 is a valuable biomarker for predicting response of advanced non-small cell lung cancer patients to hypofractionated radiotherapy and PD-1 blockade.
Kang P, Li Y, Hu Z, Lei M, Cheng J, Guo X, Zhang L, Lin S, Yuan Q
International immunopharmacology 2022 Aug;109:108732
International immunopharmacology 2022 Aug;109:108732
Downregulation of PD-L1 and HLA-I in non-small cell lung cancer with ALK fusion.
Mu D, Guo J, Yu W, Zhang J, Ren X, Han Y
Thoracic cancer 2022 Apr;13(8):1153-1163
Thoracic cancer 2022 Apr;13(8):1153-1163
SIGLEC15 amplifies immunosuppressive properties of tumor-associated macrophages in pancreatic cancer.
Li TJ, Jin KZ, Li H, Ye LY, Li PC, Jiang B, Lin X, Liao ZY, Zhang HR, Shi SM, Lin MX, Fei QL, Xiao ZW, Xu HX, Liu L, Yu XJ, Wu WD
Cancer letters 2022 Apr 1;530:142-155
Cancer letters 2022 Apr 1;530:142-155
Paraspeckle Promotes Hepatocellular Carcinoma Immune Escape by Sequestering IFNGR1 mRNA.
Zan J, Zhao X, Deng X, Ding H, Wang B, Lu M, Wei Z, Huang Z, Wang S
Cellular and molecular gastroenterology and hepatology 2021;12(2):465-487
Cellular and molecular gastroenterology and hepatology 2021;12(2):465-487
ACSL4 Expression Is Associated With CD8+ T Cell Infiltration and Immune Response in Bladder Cancer.
Luo W, Wang J, Dai X, Zhang H, Qu Y, Xiao W, Ye D, Zhu Y
Frontiers in oncology 2021;11:754845
Frontiers in oncology 2021;11:754845
A Novel Strategy Conjugating PD-L1 Polypeptide With Doxorubicin Alleviates Chemotherapeutic Resistance and Enhances Immune Response in Colon Cancer.
Wang M, Shu XS, Li M, Zhang Y, Yao Y, Huang X, Li J, Wei P, He Z, Lu J, Ying Y
Frontiers in oncology 2021;11:737323
Frontiers in oncology 2021;11:737323
Clinical Relevance and Prognostic Value of the Neuronal Protein Neuroligin 2 in Breast Cancer.
Zhang G, Sun Y, Wu ZS, Huang X
Frontiers in oncology 2021;11:630257
Frontiers in oncology 2021;11:630257
Development of bispecific anti-c-Met/PD-1 diabodies for the treatment of solid tumors and the effect of c-Met binding affinity on efficacy.
Yuan Q, Liang Q, Sun Z, Yuan X, Hou W, Wang Y, Wang H, Yu M
Oncoimmunology 2021;10(1):1914954
Oncoimmunology 2021;10(1):1914954
Injectable shear-thinning polylysine hydrogels for localized immunotherapy of gastric cancer through repolarization of tumor-associated macrophages.
Yang Y, Yang Y, Chen M, Chen J, Wang J, Ma Y, Qian H
Biomaterials science 2021 Sep 28;9(19):6597-6608
Biomaterials science 2021 Sep 28;9(19):6597-6608
Hyperbaric oxygen treatment on keloid tumor immune gene expression.
Wang CH, Shan MJ, Liu H, Hao Y, Song KX, Wu HW, Meng T, Feng C, Qi Z, Wang Z, Wang YB
Chinese medical journal 2021 Sep 13;134(18):2205-2213
Chinese medical journal 2021 Sep 13;134(18):2205-2213
Cancer-cell-biomimetic Upconversion nanoparticles combining chemo-photodynamic therapy and CD73 blockade for metastatic triple-negative breast cancer.
Jin F, Qi J, Liu D, You Y, Shu G, Du Y, Wang J, Xu X, Ying X, Ji J, Du Y
Journal of controlled release : official journal of the Controlled Release Society 2021 Sep 10;337:90-104
Journal of controlled release : official journal of the Controlled Release Society 2021 Sep 10;337:90-104
A novel mechanism of lung cancer inhibition by methionine enkephalin through remodeling the immune status of the tumor microenvironment.
Zhang S, Huang H, Handley M, Griffin N, Bai X, Shan F
International immunopharmacology 2021 Oct;99:107999
International immunopharmacology 2021 Oct;99:107999
CMTM6 expression in M2 macrophages is a potential predictor of PD-1/PD-L1 inhibitor response in colorectal cancer.
Wu X, Lan X, Hu W, Zhang W, Lai X, Xu S, Li J, Qiu W, Wang W, Xiao J, Wang F, Ding Y, Liang L
Cancer immunology, immunotherapy : CII 2021 Nov;70(11):3235-3248
Cancer immunology, immunotherapy : CII 2021 Nov;70(11):3235-3248
Dipeptidyl Peptidase (DPP)-4 Inhibitor Impairs the Outcomes of Patients with Type 2 Diabetes Mellitus After Curative Resection for Colorectal Cancer.
Saito A, Kitayama J, Horie H, Koinuma K, Kawashima R, Ohzawa H, Yamaguchi H, Kawahira H, Mimura T, Lefor AK, Sata N
Cancer research communications 2021 Nov;1(2):106-114
Cancer research communications 2021 Nov;1(2):106-114
A multi-effective and long-acting immunotherapy through one single hydrogel based injection.
Wang M, Cheng X, Luo L, Liu Y, Cao F, Zhao S, Peng H, Hong C, Jin L, Deng L, Xin H, Wang X
Biomaterials science 2021 Feb 21;9(4):1374-1380
Biomaterials science 2021 Feb 21;9(4):1374-1380
The impact of tobacco exposure on tumor microenvironment and prognosis in lung adenocarcinoma by integrative analysis of multi-omics data.
Lu X, Ma L, Yin X, Ji H, Qian Y, Zhong S, Yan A, Zhang Y
International immunopharmacology 2021 Dec;101(Pt B):108253
International immunopharmacology 2021 Dec;101(Pt B):108253
Tailoring Chemoimmunostimulant Bioscaffolds for Inhibiting Tumor Growth and Metastasis after Incomplete Microwave Ablation.
Shen Y, Chen L, Guan X, Han X, Bo X, Li S, Sun L, Chen Y, Yue W, Xu H
ACS nano 2021 Dec 28;15(12):20414-20429
ACS nano 2021 Dec 28;15(12):20414-20429
FABP4 deactivates NF-κB-IL1α pathway by ubiquitinating ATPB in tumor-associated macrophages and promotes neuroblastoma progression.
Miao L, Zhuo Z, Tang J, Huang X, Liu J, Wang HY, Xia H, He J
Clinical and translational medicine 2021 Apr;11(4):e395
Clinical and translational medicine 2021 Apr;11(4):e395
CD137 agonist induces gastric cancer cell apoptosis by enhancing the functions of CD8(+) T cells via NF-κB signaling.
Hu BS, Tang T, Jia JL, Xie BC, Wu TL, Sheng YY, Xue YZ, Tang HM
Cancer cell international 2020;20:513
Cancer cell international 2020;20:513
Role of GLUT-1 in the Upregulation of PD-L1 Expression After Radiotherapy and Association of PD-L1 with Favourable Overall Survival in Hypopharyngeal Cancer.
Shen LF, Zhou SH, Guo Y
OncoTargets and therapy 2020;13:11221-11235
OncoTargets and therapy 2020;13:11221-11235
Whole-Exome Sequencing Reveals New Potential Mutations Genes for Primary Mucosa-Associated Lymphoid Tissue Lymphoma Arising From the Kidney.
Wen S, Liu T, Zhang H, Zhou X, Jin H, Sun M, Yun Z, Luo H, Ni Z, Zhao R, Fan B
Frontiers in oncology 2020;10:609839
Frontiers in oncology 2020;10:609839
IDO1 Expression Increased After Neoadjuvant Therapy Predicts Poor Pathologic Response and Prognosis in Esophageal Squamous Cell Carcinoma.
Jiao R, Zheng X, Sun Y, Feng Z, Song S, Ge H
Frontiers in oncology 2020;10:1099
Frontiers in oncology 2020;10:1099
An IL6-Adenosine Positive Feedback Loop between CD73(+) γδTregs and CAFs Promotes Tumor Progression in Human Breast Cancer.
Hu G, Cheng P, Pan J, Wang S, Ding Q, Jiang Z, Cheng L, Shao X, Huang L, Huang J
Cancer immunology research 2020 Oct;8(10):1273-1286
Cancer immunology research 2020 Oct;8(10):1273-1286
The innate immune effector ISG12a promotes cancer immunity by suppressing the canonical Wnt/β-catenin signaling pathway.
Deng R, Zuo C, Li Y, Xue B, Xun Z, Guo Y, Wang X, Xu Y, Tian R, Chen S, Liu Q, Chen J, Wang J, Huang X, Li H, Guo M, Wang X, Yang M, Wu Z, Wang J, Ma J, Hu J, Li G, Tang S, Tu Z, Ji H, Zhu H
Cellular & molecular immunology 2020 Nov;17(11):1163-1179
Cellular & molecular immunology 2020 Nov;17(11):1163-1179
Metformin changes the immune microenvironment of colorectal cancer in patients with type 2 diabetes mellitus.
Saito A, Kitayama J, Horie H, Koinuma K, Ohzawa H, Yamaguchi H, Kawahira H, Mimura T, Lefor AK, Sata N
Cancer science 2020 Nov;111(11):4012-4020
Cancer science 2020 Nov;111(11):4012-4020
A Comparison of Splenic Pathologic Change and Immune Function in HBV-Related Portal Hypertension and Chinese Budd-Chiari Syndrome Patients with Hypersplenism.
Li S, Huang N, Dang X, Li L, Li Z, Zhang C, Jiang A, Kong G, Ji F, Yang J, Li Z
Viral immunology 2020 Mar;33(2):112-121
Viral immunology 2020 Mar;33(2):112-121
Single-Cell Transcriptome Analysis Reveals Intratumoral Heterogeneity in ccRCC, which Results in Different Clinical Outcomes.
Hu J, Chen Z, Bao L, Zhou L, Hou Y, Liu L, Xiong M, Zhang Y, Wang B, Tao Z, Chen K
Molecular therapy : the journal of the American Society of Gene Therapy 2020 Jul 8;28(7):1658-1672
Molecular therapy : the journal of the American Society of Gene Therapy 2020 Jul 8;28(7):1658-1672
NIR-Triggered Sequentially Responsive Nanocarriers Amplified Cascade Synergistic Effect of Chemo-Photodynamic Therapy with Inspired Antitumor Immunity.
Jin F, Qi J, Zhu M, Liu D, You Y, Shu G, Du Y, Wang J, Yu H, Sun M, Xu X, Shen Q, Ying X, Ji J, Du Y
ACS applied materials & interfaces 2020 Jul 22;12(29):32372-32387
ACS applied materials & interfaces 2020 Jul 22;12(29):32372-32387
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