CABT-B12018

antibody from Creative Diagnostics

Targeting: LILRB3 CD85a, HL9, ILT5, LIR-3, LIR3, PIR-B, PIRB

Flow cytometry (Recommended by provider)

Antibody Data

Product number

CABT-B12018

Provider

Creative Diagnostics

Product name

Human anti-Mouse LILRB3 recombinant monoclonal antibody, clone SFB900 [FITC]

Antibody type

Monoclonal

Description

It recognozes the B isoform of the mouse paired immunoglobulin-like receptor (PIR-A and PIR-B) antigen, a single-pass type I membrane protein which is also known as leukocyte immunoglobulin-like receptor 3 (LIR-3). Cell surface expression of PIR molecules on myeloid and B lineage cells increase with cellular differentiation and activation. PIR molecules are also expressed on dendritic cells, monocytes/macrophages, and mast cells in varying levels, but not on T cells and NK cells. PIRs functions as receptors for class I MHC antigens. PIR-B down-regulates antigen-induced B cell\u2013activation by recruiting phosphatases to its immunoreceptor tyrosine-based inhibitor motifs (ITIM). Additional information: It displays negligible binding to Fc receptors.

Reactivity

Mouse

Host

Human

Conjugate

Green dye

Isotype

IgG

Antibody clone number

SFB900

Vial size

150 _g in 1 mL

Storage

Store protected from light at 2ÿ8 °C. Do not freeze.