Antibody data
- Antibody Data
- Antigen structure
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- Product number
- TAB-028 - Provider product page
- Provider
- Creative Biolabs
- Product name
- Anti-Human CD20 Recombinant Antibody (Ofatumumab)
- Antibody type
- Monoclonal
- Description
- Recombinant monoclonal antibody to Human CD20. Ofatumumab (trade name Arzerra, also known as HuMax-CD20) is a human monoclonal antibody (for the CD20 protein) which appears to inhibit early-stage B lymphocyte activation. It is FDA approved for treating chronic lymphocytic leukemia that is refractory to fludarabine and Campath and has also shown potential in treating Follicular non-Hodgkin's lymphoma, Diffuse large B cell lymphoma, rheumatoid arthritis and relapsing remitting multiple sclerosis. Ofatumumab has also received conditional approval in Europe for the treatment of refractory chronic lymphocytic leukemia. This makes ofatumumab the first marketing application for an antibody, as well as the first human monoclonal antibody which targets the CD20 molecule that will be available for patients with refractory CLL.
- Reactivity
- Human
- Host
- Human
- Storage
- 4¡ãC. For long term storage, aliquot and store at -20¡ãC. Repeated thawing and freezing must be avoided.
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