MAB4383

antibody from Abnova Corporation

Targeting: MS4A1 B1, Bp35, CD20, MS4A2

No application information provided.

Antibody Data

Product number

MAB4383

Provider

Abnova Corporation

Proper citation

Abnova Corporation Cat#MAB4383, RRID:AB_10629007

Product name

MS4A1 monoclonal antibody, clone LT20 (APC)

Antibody type

Monoclonal

Description

Mouse monoclonal antibody raised against native MS4A1.

Isotype

IgG

Antibody clone number

LT20

Storage

Store in the dark at 4°C. Do not freeze.Avoid prolonged exposure to light.Aliquot to avoid repeated freezing and thawing.

References

Submitted references

The biological activity of human CD20 monoclonal antibodies is linked to unique epitopes on CD20.

Teeling JL, Mackus WJ, Wiegman LJ, van den Brakel JH, Beers SA, French RR, van Meerten T, Ebeling S, Vink T, Slootstra JW, Parren PW, Glennie MJ, van de Winkel JG
Journal of immunology (Baltimore, Md. : 1950) 2006 Jul 1;177(1):362-71

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CD20-induced lymphoma cell death is independent of both caspases and its redistribution into triton X-100 insoluble membrane rafts.

Chan HT, Hughes D, French RR, Tutt AL, Walshe CA, Teeling JL, Glennie MJ, Cragg MS
Cancer research 2003 Sep 1;63(17):5480-9

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Alanine-170 and proline-172 are critical determinants for extracellular CD20 epitopes; heterogeneity in the fine specificity of CD20 monoclonal antibodies is defined by additional requirements imposed by both amino acid sequence and quaternary structure.

Polyak MJ, Deans JP
Blood 2002 May 1;99(9):3256-62