NBP2-44743-0.1ml

antibody from Novus Biologicals
Targeting: MS4A1 B1, Bp35, CD20, MS4A2
Provider product page for NBP2-44743-0.1ml

Antibody data

Product number
NBP2-44743-0.1ml - Provider product page
Provider
Novus Biologicals
Product name
Mouse Monoclonal CD20 Antibody
Antibody type
Monoclonal
Description
Tissue culture supernatant. Recognizes a protein of 30-33kDa, which is identified as CD20. Its epitope is located in the cytoplasmic domain of CD20 and was, therefore, ascribed as CD20cy in the 5th Workshop. CD20 is a non-Ig differentiation antigen of B-cells and its expression is restricted to normal and neoplastic B-cells, being absent from all other leukocytes and tissues. CD20 is expressed by pre B-cells and persists during all stages of B-cell maturation but is lost upon terminal differentiation into plasma cells. This MAb can be used for immunophenotyping of leukemia and malignant cells, B lymphocyte detection in peripheral blood and B cell localization in tissues. It reacts with the majority of B-cells present in peripheral blood and lymphoid tissues and their derived lymphomas. In lymphoid tissue, germinal center blasts and B-immunoblasts are particularly reactive. It is a reliable antibody for ascribing a B-cell phenotype in known lymphoid tissues. Rarely, CD20-positive T-cell lymphomas have been reported. Reactivity has also been noted with Reed-Sternberg cells in cases of Hodgkins disease, particularly of lymphocyte predominant type.
Reactivity
Human, Rat, Bovine, Canine, Porcine, Simian
Host
Mouse
Isotype
IgG
Vial size
0.1 ml
Storage
Store at 4C.
MS4A1 protein structure - NBP2-44743-0.1ml shown in red.