Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations [0]
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- Product number
- ABIN320181 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1) antibody (FITC)
- Antibody type
- Monoclonal
- Antigen
- NS-O cells transfected with human CD20. Spleen cells from immunised BALB/c mice were fused with cells of the mouse myeloma cell line NS1.
- Description
- Affinity Chromatography on Protein A.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Green dye
- Isotype
- IgG
- Antibody clone number
- AT80
- Vial size
- 25 μg
- Concentration
- 0.1 mg/mL
- Storage
- Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light
Submitted references CD20-induced lymphoma cell death is independent of both caspases and its redistribution into triton X-100 insoluble membrane rafts.
Complement-mediated lysis by anti-CD20 mAb correlates with segregation into lipid rafts.
Alanine-170 and proline-172 are critical determinants for extracellular CD20 epitopes; heterogeneity in the fine specificity of CD20 monoclonal antibodies is defined by additional requirements imposed by both amino acid sequence and quaternary structure.
High-dose leptin activates human leukocytes via receptor expression on monocytes.
Chan HT, Hughes D, French RR, Tutt AL, Walshe CA, Teeling JL, Glennie MJ, Cragg MS
Cancer research 2003 Sep 1;63(17):5480-9
Cancer research 2003 Sep 1;63(17):5480-9
Complement-mediated lysis by anti-CD20 mAb correlates with segregation into lipid rafts.
Cragg MS, Morgan SM, Chan HT, Morgan BP, Filatov AV, Johnson PW, French RR, Glennie MJ
Blood 2003 Feb 1;101(3):1045-52
Blood 2003 Feb 1;101(3):1045-52
Alanine-170 and proline-172 are critical determinants for extracellular CD20 epitopes; heterogeneity in the fine specificity of CD20 monoclonal antibodies is defined by additional requirements imposed by both amino acid sequence and quaternary structure.
Polyak MJ, Deans JP
Blood 2002 May 1;99(9):3256-62
Blood 2002 May 1;99(9):3256-62
High-dose leptin activates human leukocytes via receptor expression on monocytes.
Zarkesh-Esfahani H, Pockley G, Metcalfe RA, Bidlingmaier M, Wu Z, Ajami A, Weetman AP, Strasburger CJ, Ross RJ
Journal of immunology (Baltimore, Md. : 1950) 2001 Oct 15;167(8):4593-9
Journal of immunology (Baltimore, Md. : 1950) 2001 Oct 15;167(8):4593-9
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