ABIN320181

antibody from antibodies-online

Targeting: MS4A1 B1, Bp35, CD20, MS4A2

Flow cytometry (Recommended by provider)

Antibody Data

Product number

ABIN320181

Provider

antibodies-online

Product name

anti-Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1) antibody (FITC)

Antibody type

Monoclonal

Antigen

NS-O cells transfected with human CD20. Spleen cells from immunised BALB/c mice were fused with cells of the mouse myeloma cell line NS1.

Description

Affinity Chromatography on Protein A.

Reactivity

Human

Host

Mouse

Conjugate

Green dye

Isotype

IgG

Antibody clone number

AT80

Vial size

25 μg

Concentration

0.1 mg/mL

Storage

Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.

Handling

Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light

References

Submitted references

CD20-induced lymphoma cell death is independent of both caspases and its redistribution into triton X-100 insoluble membrane rafts.

Chan HT, Hughes D, French RR, Tutt AL, Walshe CA, Teeling JL, Glennie MJ, Cragg MS
Cancer research 2003 Sep 1;63(17):5480-9

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Complement-mediated lysis by anti-CD20 mAb correlates with segregation into lipid rafts.

Cragg MS, Morgan SM, Chan HT, Morgan BP, Filatov AV, Johnson PW, French RR, Glennie MJ
Blood 2003 Feb 1;101(3):1045-52

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Alanine-170 and proline-172 are critical determinants for extracellular CD20 epitopes; heterogeneity in the fine specificity of CD20 monoclonal antibodies is defined by additional requirements imposed by both amino acid sequence and quaternary structure.

Polyak MJ, Deans JP
Blood 2002 May 1;99(9):3256-62

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High-dose leptin activates human leukocytes via receptor expression on monocytes.

Zarkesh-Esfahani H, Pockley G, Metcalfe RA, Bidlingmaier M, Wu Z, Ajami A, Weetman AP, Strasburger CJ, Ross RJ
Journal of immunology (Baltimore, Md. : 1950) 2001 Oct 15;167(8):4593-9