14486-1-AP

antibody from Proteintech Group

Targeting: CD34

Provider product page for 14486-1-AP

Western blot

ELISA

Immunocytochemistry

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [71]
Comments [0]
Validations
Western blot [1]
Immunohistochemistry [3]

Submit

Product number: 14486-1-AP - Provider product page
Provider: Proteintech Group
Proper citation: Proteintech Cat#14486-1-AP, RRID:AB_2228975
Product name: CD34 antibody
Antibody type: Polyclonal
Description: CD34 antibody (Cat. #14486-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IHC, WB,ELISA.
Reactivity: Human
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

CD34 protein structure - 14486-1-AP shown in red.

Submitted references A TSHR-Targeting Aptamer in Monocytes Correlating with Clinical Activity in TAO.

Cao J, Zhang F, Chen H, Wu B, Yin J, Chenzhao C, Xiong W
International journal of nanomedicine 2024;19:3577-3588

Increased Piezo1 expression in myofibroblasts in patients with symptomatic carotid atherosclerotic plaques undergoing carotid endarterectomy: A pilot study.

Konishi T, Kamiyama K, Osato T, Yoshimoto T, Aoki T, Anzai T, Tanaka S
Vascular 2024 Oct;32(5):1063-1069

Antibacterial and Anti-Inflammatory Polysaccharide from Fructus Ligustri Lucidi Incorporated in PVA/Pectin Hydrogels Accelerate Wound Healing.

Xi Y, Hu L, Chen X, Zuo L, Bai X, Du W, Xu N
Molecules (Basel, Switzerland) 2024 Mar 22;29(7)

A transcriptome based molecular classification scheme for cholangiocarcinoma and subtype-derived prognostic biomarker.

Fan Z, Zou X, Wang G, Liu Y, Jiang Y, Wang H, Zhang P, Wei F, Du X, Wang M, Sun X, Ji B, Hu X, Chen L, Zhou P, Wang D, Bai J, Xiao X, Zuo L, Xia X, Yi X, Lv G
Nature communications 2024 Jan 11;15(1):484

The Potential of Berberine to Target Telocytes in Rabbit Heart.

Yang M, Yang T, Mei L, Zhang Y, Liang C, Bai X, Zhang Z, Shi Y, Chen Q
Planta medica 2024 Feb;90(2):84-95

FGF19 promotes nasopharyngeal carcinoma progression by inducing angiogenesis via inhibiting TRIM21-mediated ANXA2 ubiquitination.

Shi S, Zhang Q, Zhang K, Chen W, Xie H, Pan S, Xue Z, You B, Zhao J, You Y
Cellular oncology (Dordrecht, Netherlands) 2024 Feb;47(1):283-301

Inhibition of infantile hemangioma growth and promotion of apoptosis via VEGF/PI3K/Akt axis by 755-nm long-pulse alexandrite laser.

Ke C, Chen C, Yang M, Chen H, Ke Y, Li L
Biomedical journal 2024 Aug;47(4):100675

Human Umbilical Cord Mesenchymal Stem Cells Repair Endothelial Injury and Dysfunction by Regulating NLRP3 to Inhibit Endothelial Cell Pyroptosis in Kawasaki Disease.

Xu T, Chen T, Fang H, Shen X, Shen X, Tang Z, Zhao J
Inflammation 2024 Apr;47(2):483-502

Reciprocal negative feedback between Prrx1 and miR-140-3p regulates rapid chondrogenesis in the regenerating antler.

Hu P, Zhang G, Ba H, Ren J, Li J, Wang Z, Li C
Cellular & molecular biology letters 2024 Apr 20;29(1):56

Primary extra-gastrointestinal stromal tumor of retroperitoneum: Clinicopathologic characteristics and prognosis of six cases.

Lin J, Liao W, Wang J, Li W, Tang X, Li H, Yi X, Lu X, Chen Z, Zhu B, Feng X, Diao D
Frontiers in oncology 2023;13:1033598

Itraconazole inhibits proliferation, induces apoptosis, and reduces angiogenesis of hemangioma endothelial cells by downregulating the hedgehog signaling pathway.

Dong J, Cui J, Shi X, Wang T, Liu S
Heliyon 2023 Sep;9(9):e19244

Venlafaxine antagonizes the noradrenaline-promoted colon cancer progression by inhibiting the norepinephrine transporter.

Zhang H, Han J, Zhang J, Miao J, Li F, Tang K, Zhou K, Duan B, Li W, Cheng J, Sun Y, Hou N, Huang C
Cell death discovery 2023 May 8;9(1):152

EPAS1 prevents telomeric damage-induced senescence by enhancing transcription of TRF1, TRF2, and RAD50.

Li KQ, Liu GJ, Liu XY, Chen QF, Huang XY, Tu Q, Zhang J, Chang Q, Xie YH, Hua R, Xu DM, Liu Z, Zhao B
Zoological research 2023 May 18;44(3):636-649

m(6)A methylation reader IGF2BP2 activates endothelial cells to promote angiogenesis and metastasis of lung adenocarcinoma.

Fang H, Sun Q, Zhou J, Zhang H, Song Q, Zhang H, Yu G, Guo Y, Huang C, Mou Y, Jia C, Song Y, Liu A, Song K, Lu C, Tian R, Wei S, Yang D, Chen Y, Li T, Wang K, Yu Y, Lv Y, Mo K, Sun P, Yu X, Song X
Molecular cancer 2023 Jun 23;22(1):99

Role of the blood-spinal cord barrier: An adheren junction regulation mechanism that promotes chronic postsurgical pain.

Zhao Q, Yao J, Meng B, Shen S, Cao S
Biochemical and biophysical research communications 2023 Jun 11;660:65-72

Targeting the mitochondrial calcium uniporter inhibits cancer progression and alleviates cisplatin resistance in esophageal squamous cell carcinoma.

Miao Y, Wang X, Lai Y, Huang Y, Yin H, Meng X, Liu H, Hou R, Lin W, Zhang X, Zhang X, Chai BC, Zhang F, Guo L, Yang S
International journal of oncology 2023 Jul;63(1)

Placental homing peptide guides HIF1α‑silenced exosomes conjugates for targeted enhancement of invasion of trophoblast cells.

Chen F, Cen H, Mao D, Feng R
Molecular medicine reports 2023 Jul;28(1)

Self-powered enzyme-linked microneedle patch for scar-prevention healing of diabetic wounds.

Zhang X, Wang Z, Jiang H, Zeng H, An N, Liu B, Sun L, Fan Z
Science advances 2023 Jul 14;9(28):eadh1415

Imbalance in ALR ubiquitination accelerates the progression of nonalcoholic steatohepatitis to hepatocellular carcinoma.

Zheng M, Ai Z, Guo Y, Chen Y, Xie P, An W
Oncogene 2023 Jan;42(4):308-321

The role and molecular mechanism of gut microbiota in Graves' orbitopathy.

Li Y, Luo B, Tong B, Xie Z, Cao J, Bai X, Peng Y, Wu Y, Wang W, Qi X
Journal of endocrinological investigation 2023 Feb;46(2):305-317

Exosomal circTUBGCP4 promotes vascular endothelial cell tipping and colorectal cancer metastasis by activating Akt signaling pathway.

Chen C, Liu Y, Liu L, Si C, Xu Y, Wu X, Wang C, Sun Z, Kang Q
Journal of experimental & clinical cancer research : CR 2023 Feb 15;42(1):46

CXCL8 Promotes Endothelial-to-Mesenchymal Transition of Endothelial Cells and Protects Cells from Erastin-Induced Ferroptosis via CXCR2-Mediated Activation of the NF-κB Signaling Pathway.

Ji HZ, Chen L, Ren M, Li S, Liu TY, Chen HJ, Yu HH, Sun Y
Pharmaceuticals (Basel, Switzerland) 2023 Aug 25;16(9)

Expression of Dickkopf-1 and Twist2 in Cervical Squamous Cell Carcinoma and Their Correlation with Vasculogenic Mimicry.

Wang B, Zhang H, Wei L, Li Y
Journal of healthcare engineering 2022;2022:9288476

Tissue Kallikrein Protects Rat Prostate against the Inflammatory Damage in a Chronic Autoimmune Prostatitis Model via Restoring Endothelial Function in a Bradykinin Receptor B2-Dependent Way.

Zhang M, Lin D, Luo C, Wei P, Cui K, Chen Z
Oxidative medicine and cellular longevity 2022;2022:1247806

Bevacizumab is an Efficient Therapeutic Approach with Low Side Effects in Patient-Derived Xenografts of Adenoid Cystic Carcinoma of the Lacrimal Gland.

Zhang J, Yan X, Liu R, Wu S, Liu Q, Li J, Ma J
Cancer management and research 2022;14:1023-1032

Connective tissue growth factor promotes cementogenesis and cementum repair via Cx43/β-catenin axis.

Wu Z, He Y, Chen S, Zhu L, Wang J, Zhang D, Xie J, Zou S, Zhou C
Stem cell research & therapy 2022 Sep 6;13(1):460

Shikonin as a WT1 Inhibitor Promotes Promyeloid Leukemia Cell Differentiation.

Guo Z, Sun L, Xia H, Tian S, Liu M, Hou J, Li J, Lin H, Du G
Molecules (Basel, Switzerland) 2022 Nov 26;27(23)

Construction and a preliminary study of paracrine effect of bone marrow-derived endothelial progenitor cell sheet.

Xue F, Bai Y, Jiang Y, Liu J, Jian K
Cell and tissue banking 2022 Mar;23(1):185-197

Novel magnetic silk fibroin scaffolds with delayed degradation for potential long-distance vascular repair.

Liu X, Sun Y, Chen B, Li Y, Zhu P, Wang P, Yan S, Li Y, Yang F, Gu N
Bioactive materials 2022 Jan;7:126-143

A pan-cancer analysis of molecular characteristics and oncogenic role of gasdermins.

Mu M, Yu Q, Zhang Q, Guo J, Wang X, Sun X, Yu J
Cancer cell international 2022 Feb 14;22(1):80

A novel type of mesenchymal stem cells derived from bovine metanephric mesenchyme.

Wang Y, Wu Y, Liu Y, Zhang Y, Yang X, Gao Y, Guan W
Tissue & cell 2022 Dec;79:101970

Apelin/APJ-Manipulated CaMKK/AMPK/GSK3β Signaling Works as an Endogenous Counterinjury Mechanism in Promoting the Vitality of Random-Pattern Skin Flaps.

Lou ZL, Zhang CX, Li JF, Chen RH, Wu WJ, Hu XF, Shi HC, Gao WY, Zhao QF
Oxidative medicine and cellular longevity 2021;2021:8836058

Characteristics of pulmonary microvascular structure in postnatal yaks.

Wan R, Zhao Z, Zhao M, Hu K, Zhai J, Yu H, Wei Q
Scientific reports 2021 Sep 14;11(1):18265

Hypoxic tubular epithelial cells regulate the angiogenesis of HMEC-1 cells via mediation of Rab7/MMP-2 axis.

Yang Y, Wang J, Zhang Y, Hu X, Li L, Chen P
Aging 2021 Oct 25;13(20):23769-23779

Yiqi-Huoxue granule promotes angiogenesis of ischemic myocardium through miR-126/PI3K/Akt axis in endothelial cells.

Gao H, Peng C, Wu L, Gao S, Wang Z, Dai L, Wu H
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Nov;92:153713

Novel insights into the role of 5-Methylcytosine RNA methylation in human abdominal aortic aneurysm.

He Y, Zhang H, Yin F, Guo P, Wang S, Wu Y, Xin S, Han Y, Zhang J
Frontiers in bioscience (Landmark edition) 2021 Nov 30;26(11):1147-1165

Nuclear exosome HMGB3 secreted by nasopharyngeal carcinoma cells promotes tumour metastasis by inducing angiogenesis.

Zhang K, Liu D, Zhao J, Shi S, He X, Da P, You Y, You B
Cell death & disease 2021 May 28;12(6):554

Acidosis induces synovial fibroblasts to release vascular endothelial growth factor via acid-sensitive ion channel 1a.

Qian X, Zhang Y, Tao J, Niu R, Song S, Wang C, Peng X, Chen F
Laboratory investigation; a journal of technical methods and pathology 2021 Mar;101(3):280-291

Autophagy-induced p62 accumulation is required for curcumol to regulate KLF5-mediated angiogenesis in liver sinusoidal endothelial cells.

Gao L, Yang X, Liang B, Jia Y, Tan S, Chen A, Cao P, Zhang Z, Zheng S, Sun L, Zhang F, Shao J
Toxicology 2021 Mar 30;452:152707

Curcumol inhibits KLF5-dependent angiogenesis by blocking the ROS/ERK signaling in liver sinusoidal endothelial cells.

Gao L, Yang X, Li Y, Wang Z, Wang S, Tan S, Chen A, Cao P, Shao J, Zhang Z, Zhang F, Zheng S
Life sciences 2021 Jan 1;264:118696

miR-126 regulates angiogenesis in myocardial ischemia by targeting HIF-1α.

Gao S, Gao H, Dai L, Han Y, Lei Z, Wang X, Chang H, Liu S, Wang Z, Tong H, Wu H
Experimental cell research 2021 Dec 15;409(2):112925

ICAM1 initiates CTC cluster formation and trans-endothelial migration in lung metastasis of breast cancer.

Taftaf R, Liu X, Singh S, Jia Y, Dashzeveg NK, Hoffmann AD, El-Shennawy L, Ramos EK, Adorno-Cruz V, Schuster EJ, Scholten D, Patel D, Zhang Y, Davis AA, Reduzzi C, Cao Y, D'Amico P, Shen Y, Cristofanilli M, Muller WA, Varadan V, Liu H
Nature communications 2021 Aug 11;12(1):4867

Clopidogrel-Induced Gastric Injury in Rats is Attenuated by Stable Gastric Pentadecapeptide BPC 157.

Wu H, Wei M, Li N, Lu Q, Shrestha SM, Tan J, Zhang Z, Wu G, Shi R
Drug design, development and therapy 2020;14:5599-5610

Chronic Unpredictable Mild Stress Accelerates the Growth of Bladder Cancer in a Xenograft Mouse Model.

Zhou Q, Ding W, Qian Z, Jiang G, Sun C, Xu K
Psychology research and behavior management 2020;13:1289-1297

Circadian Clock Protein PERIOD2 Suppresses the PI3K/Akt Pathway and Promotes Cisplatin Sensitivity in Ovarian Cancer.

Wang Z, Li F, Wei M, Zhang S, Wang T
Cancer management and research 2020;12:11897-11908

A Histomorphological Study of the Divergent Corpus Spongiosum Surrounding the Urethral Plate in Hypospadias.

Bao X, Huang Y, Lyu Y, Xi Z, Xie H, Fu Q, Song L, Chen F
Urology 2020 Oct;144:188-193

Pharmacological Effects of Fasudil on Flap Survival in a Rodent Model.

Ji E, Wang J, Wang L, Pan Z, Gao W
The Journal of surgical research 2020 Nov;255:575-582

Chitosan-calcium alginate dressing promotes wound healing: A preliminary study.

Zhao WY, Fang QQ, Wang XF, Wang XW, Zhang T, Shi BH, Zheng B, Zhang DD, Hu YY, Ma L, Tan WQ
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2020 May;28(3):326-337

lncRNA PVT1 Promotes Tumorigenesis of Colorectal Cancer by Stabilizing miR-16-5p and Interacting with the VEGFA/VEGFR1/AKT Axis.

Wu H, Wei M, Jiang X, Tan J, Xu W, Fan X, Zhang R, Ding C, Zhao F, Shao X, Zhang Z, Shi R, Zhang W, Wu G
Molecular therapy. Nucleic acids 2020 Jun 5;20:438-450

LncRNA Gm16410 regulates PM(2.5)-induced lung Endothelial-Mesenchymal Transition via the TGF-β1/Smad3/p-Smad3 pathway.

Ma K, Li C, Xu J, Ren F, Xu X, Liu C, Niu B, Li F
Ecotoxicology and environmental safety 2020 Dec 1;205:111327

Inhibition of DNA Methyltransferase by RG108 Promotes Pluripotency-Related Character of Porcine Bone Marrow Mesenchymal Stem Cells.

Li Q, Zhai Y, Man X, Zhang S, An X
Cellular reprogramming 2020 Apr;22(2):82-89

Kallistatin correlates with inflammation in abdominal aortic aneurysm and suppresses its formation in mice.

He Y, Han Y, Xing J, Zhai X, Wang S, Xin S, Zhang J
Cardiovascular diagnosis and therapy 2020 Apr;10(2):107-123

Therapeutic Effects of Human Urine-Derived Stem Cells in a Rat Model of Cisplatin-Induced Acute Kidney Injury In Vivo and In Vitro.

Sun B, Luo X, Yang C, Liu P, Yang Y, Dong X, Yang Z, Xu J, Zhang Y, Li L
Stem cells international 2019;2019:8035076

SDF-1α promotes repair of myocardial ischemic necrosis zones in rats.

Cai X, Zhu Z, Zhang Y, Tian X
International journal of clinical and experimental pathology 2019;12(6):1956-1967

Inhibitory effect of taspine derivative TAD1822-7 on tumor cell growth and angiogenesis via suppression of EphrinB2 and related signaling pathways.

Liu R, Yu R, Cui Y, Fan M, Wang B, Zhang Y
Acta pharmaceutica (Zagreb, Croatia) 2019 Sep 1;69(3):423-431

Molecular interplay between microRNA-130a and PTEN in palmitic acid-mediated impaired function of endothelial progenitor cells: Effects of metformin.

Gu X, Wang XQ, Lin MJ, Liang H, Fan SY, Wang L, Yan X, Liu W, Shen FX
International journal of molecular medicine 2019 May;43(5):2187-2198

Alpinate Oxyphyllae extracts enhance the longevity and homing of mesenchymal stem cells and augment their protection against senescence in H9c2 cells.

Chang YM, Asokan Shibu M, Tsai CT, Tsai CC, Lin SL, Chang CC, Viswanadha VP, Chen RJ, Chang JH, Huang CY
Journal of cellular physiology 2019 Jul;234(7):12042-12050

Increased m6A methylation level is associated with the progression of human abdominal aortic aneurysm.

He Y, Xing J, Wang S, Xin S, Han Y, Zhang J
Annals of translational medicine 2019 Dec;7(24):797

Overexpression of Cyclophilin A in Human Periapical Lesions.

Wang Y, Liu G, Zhang J, Zhu L, Yu J, Zhu S, Lv F, Peng B
Journal of endodontics 2019 Dec;45(12):1496-1503

Astaxanthin ameliorates renal interstitial fibrosis and peritubular capillary rarefaction in unilateral ureteral obstruction.

Zhao J, Meng M, Zhang J, Li L, Zhu X, Zhang L, Wang C, Gao M
Molecular medicine reports 2019 Apr;19(4):3168-3178

Ligand Activation of PPARγ by Ligustrazine Suppresses Pericyte Functions of Hepatic Stellate Cells via SMRT-Mediated Transrepression of HIF-1α.

Zhang F, Lu S, He J, Jin H, Wang F, Wu L, Shao J, Chen A, Zheng S
Theranostics 2018;8(3):610-626

CCN1/Cyr61 enhances the function of hepatic stellate cells in promoting the progression of hepatocellular carcinoma.

Li ZQ, Wu WR, Zhao C, Zhao C, Zhang XL, Yang Z, Pan J, Si WK
International journal of molecular medicine 2018 Mar;41(3):1518-1528

De novo lipogenesis and desaturation of fatty acids during adipogenesis in bovine adipose-derived mesenchymal stem cells.

Yue Y, Zhang L, Zhang X, Li X, Yu H
In vitro cellular & developmental biology. Animal 2018 Jan;54(1):23-31

Image-guided stem cells with functionalized self-assembling peptide nanofibers for treatment of acute myocardial infarction in a mouse model.

Li X, Chen YY, Wang XM, Gao K, Gao YZ, Cao J, Zhang ZL, Lei J, Jin ZY, Wang YN
American journal of translational research 2017;9(8):3723-3731

In vivo evaluation of the effects of simultaneous inhibition of GLUT-1 and HIF-1α by antisense oligodeoxynucleotides on the radiosensitivity of laryngeal carcinoma using micro 18F-FDG PET/CT.

Shen LF, Zhao X, Zhou SH, Lu ZJ, Zhao K, Fan J, Zhou ML
Oncotarget 2017 May 23;8(21):34709-34726

Canonical hedgehog signalling regulates hepatic stellate cell-mediated angiogenesis in liver fibrosis.

Zhang F, Hao M, Jin H, Yao Z, Lian N, Wu L, Shao J, Chen A, Zheng S
British journal of pharmacology 2017 Mar;174(5):409-423

A taspine derivative supresses Caco-2 cell growth by competitively targeting EphrinB2 and regulating its pathway.

Dai B, Wang W, Ma Y, Liu R, Zhang Y
Oncology reports 2016 Sep;36(3):1526-34

Intravenous Administration of Endothelial Colony-Forming Cells Overexpressing Integrin β1 Augments Angiogenesis in Ischemic Legs.

Goto K, Takemura G, Takahashi T, Okada H, Kanamori H, Kawamura I, Watanabe T, Morishita K, Tsujimoto A, Miyazaki N, Ushikoshi H, Kawasaki M, Mikami A, Kosai K, Minatoguchi S
Stem cells translational medicine 2016 Feb;5(2):218-26

Serum Renalase Levels Correlate with Disease Activity in Lupus Nephritis.

Qi C, Wang L, Zhang M, Shao X, Chang X, Fan Z, Cao Q, Mou S, Wang Q, Yan Y, Desir G, Ni Z
PloS one 2015;10(10):e0139627

Effect of the vascular endothelial growth factor expression level on angiopoietin-2-mediated nasopharyngeal carcinoma growth.

Chen HH, Weng BQ, Cheng KJ, Liu HY, Wang SQ, Lu YY
Vascular cell 2014 Mar 1;6(1):4

Intratumoral neutrophils: a poor prognostic factor for hepatocellular carcinoma following resection.

Li YW, Qiu SJ, Fan J, Zhou J, Gao Q, Xiao YS, Xu YF
Journal of hepatology 2011 Mar;54(3):497-505

No comments: Submit comment

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: HL-60 cells were subjected to SDS PAGE followed by western blot with 14486-1-AP(CD34 antibody) at dilution of 1:500
Sample type: cell line

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: Immunohistochemical of paraffin-embedded human endometrial cancer using 14486-1-AP(CD34 antibody) at dilution of 1:100 (under 10x lens)
Sample type: tissue

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: Immunohistochemical of paraffin-embedded human endometrial cancer using 14486-1-AP(CD34 antibody) at dilution of 1:100 (under 40x lens)
Sample type: tissue

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: The CD34 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human CD34. This antibody recognizes human, mouse antigen. The CD34 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
Appendix: 14486-1-AP.pdf

: Show more