Antibody data
- Antibody Data
- Antigen structure
- References [1]
- Comments [0]
- Validations
- Flow cytometry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 343522 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#343522, RRID:AB_2228973
- Product name
- PerCP/Cy5.5 anti-human CD34
- Antibody type
- Monoclonal
- Antigen
- CD34
- Description
- CD34, also known as gp105-120, is a type I monomeric sialomucin-like glycophosphoprotein with an approximate molecular weight of 105-120 kD. Selectively expressed on the majority of hematopoietic stem/progenitor cells, bone marrow stromal cells, capillary endothelial cells, embryonic fibroblasts, and some nervous tissue, CD34 is a commonly used marker to identify human hematopoietic stem/progenitor cells. According to the differential sensitivity to enzymatic cleavage, four groups of epitopes of CD34 have been described. CD34 mediates cell adhesion and lymphocytes homing through binding to L-selectin and E-selectin ligands.
- Reactivity
- Human, Simian
- Host
- Mouse
- Conjugate
- Far-Red dye
- Isotype
- IgG
- Vial size
- 100 tests
- Storage
- The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Submitted references A promoter DNA demethylation landscape of human hematopoietic differentiation.
Calvanese V, Fernández AF, Urdinguio RG, Suárez-Alvarez B, Mangas C, Pérez-García V, Bueno C, Montes R, Ramos-Mejía V, Martínez-Camblor P, Ferrero C, Assenov Y, Bock C, Menendez P, Carrera AC, Lopez-Larrea C, Fraga MF
Nucleic acids research 2012 Jan;40(1):116-31
Nucleic acids research 2012 Jan;40(1):116-31
No comments: Submit comment
Supportive validation
- Submitted by
- BioLegend (provider)
- Main image
- Experimental details
- Human peripheral blood leukocytes stained with CD45 FITC and 581 PerCP/Cy5.5 (top) or mouse IgG1,κ PerCP/Cy5.5 isotype control (bottom). Cytogram gated for total live CD14 negative lymphocyte population