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Immunocytochemistry
ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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- Product number
- NB110-59922 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB110-59922, RRID:AB_892347
- Product name
- Mouse Monoclonal Cytokeratin 5/14 Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified. This antibody cocktail reacts with cytokeratin 5 intermediate filament protein as well as to 50 kD cytokeratin protein designated cytokeratin 14. Basal cells of human epidermis express acidic cytokeratin 14 and basic cytokeratin 5. Cytokeratin 5 is a 58 kD protein which is closely related to cytokeratin 6. Cytokeratin 5 and 6 are expressed in basal cell epithelioma, basal cells of prostate, urothelium, vagina, squamous cell carcinomas of skin, tongue, epiglottis, and in the rectal-anal region. Cytokeratin 5 can be useful in the destinction of mesotheliomas from most adenocarcinomas. Cytokeratin 14 belongs to the type A (acidic) subfamily of low MW cytokeratins and exists in combination with cytokeratin 15. This antibody can be useful to distinguish stratified ephithelial cells from simple epithelial cells.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 6 ml
- Storage
- Store at 4C.
Submitted references Characterization of cultured epithelial cells using a novel technique not requiring enzymatic digestion for subculturing.
Characterization of a unique technique for culturing primary adult human epithelial progenitor/"stem cells".
Peramo A, Feinberg SE, Marcelo CL
Cell and tissue banking 2013 Sep;14(3):423-35
Cell and tissue banking 2013 Sep;14(3):423-35
Characterization of a unique technique for culturing primary adult human epithelial progenitor/"stem cells".
Marcelo CL, Peramo A, Ambati A, Feinberg SE
BMC dermatology 2012 Jun 24;12:8
BMC dermatology 2012 Jun 24;12:8
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Supportive validation
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- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Cytokeratin 5/14 Antibody (XM26 & LL002) [NB110-59922] - Formalin fixed paraffin embedded human tonsil stained with Cytokeratin 5/14 (NB110-59922).
