20333-1-AP

antibody from Proteintech Group

Targeting: AQP1 CHIP28, CO

Provider product page for 20333-1-AP

Western blot

ELISA

Immunoprecipitation

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [60]
Comments [0]
Validations
Western blot [1]
Immunohistochemistry [2]

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Product number: 20333-1-AP - Provider product page
Provider: Proteintech Group
Proper citation: Proteintech Cat#20333-1-AP, RRID:AB_10666159
Product name: AQP1 antibody
Antibody type: Polyclonal
Description: AQP1 antibody (Cat. #20333-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB, ELISA.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

AQP1 protein structure - 20333-1-AP shown in red.

Submitted references Novel approach for reconstruction of the three-dimensional biliary system in decellularized liver scaffold using hepatocyte progenitors.

Hirukawa K, Yagi H, Kuroda K, Watanabe M, Nishi K, Nagata S, Abe Y, Kitago M, Adachi S, Sudo R, Kitagawa Y
PloS one 2024;19(2):e0297285

Physiologic homeostasis after pig-to-human kidney xenotransplantation.

Judd E, Kumar V, Porrett PM, Hyndman KA, Anderson DJ, Jones-Carr ME, Shunk A, Epstein DR, Fatima H, Katsurada A, Satou R, Navar LG, Locke JE
Kidney international 2024 May;105(5):971-979

ESCRT-I protein UBAP1 controls ventricular expansion and cortical neurogenesis via modulating adherens junctions of radial glial cells.

Lu D, Zhi Y, Su H, Lin X, Lin J, Shi Y, Yi W, Hong C, Zhang T, Fu Z, Chen LY, Zhao Z, Li R, Xu Z, Chen W, Wang N, Xu D
Cell reports 2024 Mar 26;43(3):113818

White matter hyperintensities and the surrounding normal appearing white matter are associated with water channel disruption in the oldest old.

Silbert LC, Roese NE, Krajbich V, Hurworth J, Lahna D, Schwartz DL, Dodge HH, Woltjer RL
Alzheimer's & dementia : the journal of the Alzheimer's Association 2024 Jun;20(6):3839-3851

Porcine Kidney Organoids Derived from Naïve-like Embryonic Stem Cells.

Li M, Guo X, Cheng L, Zhang H, Zhou M, Zhang M, Yin Z, Guo T, Zhao L, Liu H, Liang X, Li R
International journal of molecular sciences 2024 Jan 4;25(1)

Electroacupuncture Improving Intestinal Barrier Function in Rats with Irritable Bowel Syndrome Through Regulating Aquaporins.

Kang X, Zhang H, Li X, Zhang K, Huang Z, Li Y, Ren X, Chai Y
Digestive diseases and sciences 2024 Apr;69(4):1143-1155

Targeting mechanics-induced trabecular meshwork dysfunction through YAP-TGFβ Ameliorates high myopia-induced ocular hypertension.

Bu Q, Zhu H, Cao G, Gong G, Su Y, Ge Q, Zhu W, Li Z, Pan X
Experimental eye research 2024 Apr;241:109853

A Flavonoid Glycoside Compound from Siraitia grosvenorii with Anti-Inflammatory and Hepatoprotective Effects In Vitro.

Wu J, Huang H, Gong L, Tian X, Peng Z, Zhu Y, Wang W
Biomolecules 2024 Apr 7;14(4)

Histone H3K27 methyltransferase EZH2 regulates apoptotic and inflammatory responses in sepsis-induced AKI.

Li B, Xia Y, Mei S, Ye Z, Song B, Yan X, Lin F, Rao T, Yu W, Mei C, Lv J, Wu M, Mao Z, Zhou X, Cheng F
Theranostics 2023;13(6):1860-1875

WT1(+) glomerular parietal epithelial progenitors promote renal proximal tubule regeneration after severe acute kidney injury.

Hong X, Nie H, Deng J, Liang S, Chen L, Li J, Gong S, Wang G, Zuo W, Hou F, Zhang F
Theranostics 2023;13(4):1311-1324

Generation and characterization of an inducible renal proximal tubule-specific CreERT2 mouse.

Liang S, Wang Y, Kang M, Deng J, Chen L, Hong X, Hou FF, Zhang F
Frontiers in cell and developmental biology 2023;11:1171637

Functional Water Channels Within the TSH Receptor: A New Paradigm for TSH Action With Disease Implications.

Latif R, Davies TF, Mezei M
Endocrinology 2023 Sep 23;164(11)

XinLi formula, a traditional Chinese decoction, alleviates chronic heart failure via regulating the interaction of AGTR1 and AQP1.

Wei XH, Liu WJ, Jiang W, Lan TH, Pan H, Ma MY, You LZ, Shang HC
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 May;113:154722

Empagliflozin reduces podocyte lipotoxicity in experimental Alport syndrome.

Ge M, Molina J, Kim JJ, Mallela SK, Ahmad A, Varona Santos J, Al-Ali H, Mitrofanova A, Sharma K, Fontanesi F, Merscher S, Fornoni A
eLife 2023 May 2;12

Distribution of Monocarboxylate Transporters in Brain and Choroid Plexus Epithelium.

Ueno M, Chiba Y, Murakami R, Miyai Y, Matsumoto K, Wakamatsu K, Takebayashi G, Uemura N, Yanase K
Pharmaceutics 2023 Jul 31;15(8)

Time-dependent laxative effect of sennoside A, the core functional component of rhubarb, is attributed to gut microbiota and aquaporins.

Zhang MM, Gong ZC, Zhao Q, Xu DQ, Fu RJ, Tang YP, Chen YY
Journal of ethnopharmacology 2023 Jul 15;311:116431

Injectable extracellular matrix hydrogels contribute to native cell infiltration in a rat partial nephrectomy model.

Kushige H, Amano Y, Yagi H, Morisaku T, Kojima H, Satou A, Hamada KI, Kitagawa Y
Journal of biomedical materials research. Part B, Applied biomaterials 2023 Jan;111(1):184-193

Novel lncRNA-prader willi/angelman region RNA, SNRPN neighbour (PWARSN) aggravates tubular epithelial cell pyroptosis by regulating TXNIP via dual way in diabetic kidney disease.

Song Y, Guo F, Zhao YY, Ma XJ, Wu LN, Yu JF, Ji HF, Shao MW, Huang FJ, Zhao L, Fan XJ, Xu YN, Wang QZ, Qin GJ
Cell proliferation 2023 Feb;56(2):e13349

Screening the effective components in treating dampness stagnancy due to spleen deficiency syndrome and elucidating the potential mechanism of Poria water extract.

Li H, Zhang D, Wang T, Luo X, Xia H, Pan X, Han S, You P, Wei Q, Liu D, Zou Z, Ye X
Chinese journal of natural medicines 2023 Feb;21(2):83-98

Aquaporin 1 is a prognostic marker and inhibits tumour progression through downregulation of Snail expression in intrahepatic cholangiocarcinoma.

Zhuang MQ, Jiang XL, Liu WD, Xie QH, Wang P, Dong LW, Hu HP, Zhou HB, Zhou YB
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2023 Aug;55(8):1133-1140

Aquaporin 1 Facilitates Ferroptosis, M1 Polarization, Mitochondrial Dysfunction, and Autophagy Damage on Lipopolysaccharide-Induced Macrophage Through Down-Regulation of P53 Signaling Pathway.

Lv W, Liang L, Liu D, Li C, Jia L, Jin Y
DNA and cell biology 2023 Aug;42(8):456-480

Identification of cell division cycle protein 20 in various forms of acute and chronic kidney injury in mice.

Swanson M, Yun J, Collier DM, Seif C, Yang CY, Regner KR, Park F
American journal of physiology. Renal physiology 2023 Aug 1;325(2):F248-F261

Pathologic light chain amyloidosis oligomer detection in urinary extracellular vesicles as a diagnostic tool for response and progression of disease.

Cooper SA, Dick CJ, Misra P, Leung N, Schinstock CA, Ramirez-Alvarado M
Frontiers in oncology 2022;12:978198

Functional differentiation and scalable production of renal proximal tubular epithelial cells from human pluripotent stem cells in a dynamic culture system.

Ngo TTT, Rossbach B, Sébastien I, Neubauer JC, Kurtz A, Hariharan K
Cell proliferation 2022 Mar;55(3):e13190

CD320 expression and apical membrane targeting in renal and intestinal epithelial cells.

Chen Y, Gu X, Zhang Y, Zhang X, Zhang C, Liu M, Sun S, Dong N, Wu Q
International journal of biological macromolecules 2022 Mar 15;201:85-92

Naringin suppressed airway inflammation and ameliorated pulmonary endothelial hyperpermeability by upregulating Aquaporin1 in lipopolysaccharide/cigarette smoke-induced mice.

Zhang HH, Zhou XJ, Zhong YS, Ji LT, Yu WY, Fang J, Ying HZ, Li CY
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Jun;150:113035

Differences in the localization of AQP1 and expression patterns of AQP isoforms in rat and mouse sciatic nerve and changes in rat AQPs expression after nerve crush injury.

Segura-Anaya E, Martínez-Gómez A, Dent MAR
IBRO neuroscience reports 2022 Jun;12:82-89

Establishment of a novel mouse peritoneal dialysis-associated peritoneal injury model.

Yu F, Chen J, Wang X, Cai Q, Luo J, Wang L, Chen K, He Y
Clinical and experimental nephrology 2022 Jul;26(7):649-658

Identification of potential plasma markers for hepatitis B virus-related chronic hepatitis and liver fibrosis/cirrhosis.

Zhao D, Yu S, Guo P, Zhang X, Tang Y, Dong C, Zhao S, Li L, Al-Dhamin Z, Ai R, Xue N, Dong S, Nan Y
Journal of medical virology 2022 Aug;94(8):3900-3910

Human Norovirus Induces Aquaporin 1 Production by Activating NF-κB Signaling Pathway.

Zhang M, Zhang B, Chen R, Li M, Zheng Z, Xu W, Zhang Y, Gong S, Hu Q
Viruses 2022 Apr 18;14(4)

Human iPSC-Derived Renal Cells Change Their Immunogenic Properties during Maturation: Implications for Regenerative Therapies.

Rossbach B, Hariharan K, Mah N, Oh SJ, Volk HD, Reinke P, Kurtz A
Cells 2022 Apr 13;11(8)

Metabolites and Biomarker Compounds of Neurodegenerative Diseases in Cerebrospinal Fluid.

Wakamatsu K, Chiba Y, Murakami R, Miyai Y, Matsumoto K, Kamada M, Nonaka W, Uemura N, Yanase K, Ueno M
Metabolites 2022 Apr 12;12(4)

Small-Molecule Induction Promotes Corneal Endothelial Cell Differentiation From Human iPS Cells.

Chen J, Ou Q, Wang Z, Liu Y, Hu S, Liu Y, Tian H, Xu J, Gao F, Lu L, Jin C, Xu GT, Cui HP
Frontiers in bioengineering and biotechnology 2021;9:788987

Effects of andrographolide on renal tubulointersticial injury and fibrosis. Evidence of its mechanism of action.

Liu W, Liang L, Zhang Q, Li Y, Yan S, Tang T, Ren Y, Mo J, Liu F, Chen X, Lan T
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Oct;91:153650

Generation of Urine-Derived Induced Pluripotent Stem Cell Line from Patients with Acute Kidney Injury.

Jin Y, Zhang M, Li M, Zhang H, Zhang F, Zhang H, Yin Z, Zhou M, Wan X, Li R, Cao C
Cellular reprogramming 2021 Oct;23(5):290-303

The hepatocyte growth factor/c-met pathway is a key determinant of the fibrotic kidney local microenvironment.

Fu H, Gui Y, Liu S, Wang Y, Bastacky SI, Qiao Y, Zhang R, Bonin C, Hargis G, Yu Y, Kreutzer DL, Biswas PS, Zhou Y, Wang Y, Tian XJ, Liu Y, Zhou D
iScience 2021 Oct 22;24(10):103112

NLRP3 inflammasome of renal tubular epithelial cells induces kidney injury in acute hemolytic transfusion reactions.

Liu Z, Chen Y, Niu B, Yin D, Feng F, Gu S, An Q, Xu J, An N, Zhang J, Yi J, Yin W, Qin X, Hu X
Clinical and translational medicine 2021 Mar;11(3):e373

Transient Receptor Potential Channel 6 Knockout Ameliorates Kidney Fibrosis by Inhibition of Epithelial-Mesenchymal Transition.

Zhang Y, Yin N, Sun A, Wu Q, Hu W, Hou X, Zeng X, Zhu M, Liao Y
Frontiers in cell and developmental biology 2020;8:602703

AQP1 modulates tendon stem/progenitor cells senescence during tendon aging.

Chen M, Li Y, Xiao L, Dai G, Lu P, Wang Y, Rui Y
Cell death & disease 2020 Mar 18;11(3):193

Higher expression levels of aquaporin (AQP)1 and AQP5 in the lungs of arid-desert living Lepus yarkandensis.

Zhang J, Li S, Liu J, Li L, Deng F, Baikeli B, Li L, Ma X, Liu G
Journal of animal physiology and animal nutrition 2020 Jul;104(4):1186-1195

Generating Multiple Kidney Progenitors and Cell Types from Human Pluripotent Stem Cells.

Hariharan K, Reinke P, Kurtz A
Methods in molecular biology (Clifton, N.J.) 2019;1926:103-115

Higher Expression Levels of Aquaporin Family of Proteins in the Kidneys of Arid-Desert Living Lepus yarkandensis.

Zhang J, Li S, Deng F, Baikeli B, Huang S, Wang B, Liu G
Frontiers in physiology 2019;10:1172

Distribution of aquaporins and sodium transporters in the gastrointestinal tract of a desert hare, Lepus yarkandensis.

Zhang J, Li S, Deng F, Baikeli B, Yu W, Liu G
Scientific reports 2019 Nov 12;9(1):16639

Escin suppresses HMGB1-induced overexpression of aquaporin-1 and increased permeability in endothelial cells.

Chen C, Wang S, Chen J, Liu X, Zhang M, Wang X, Xu W, Zhang Y, Li H, Pan X, Si M
FEBS open bio 2019 May;9(5):891-900

PEDF decreases cardiomyocyte edema during oxygen‑glucose deprivation and recovery via inhibiting lactate accumulation and expression of AQP1.

Huang B, Miao H, Yuan Y, Qiu F, Liu X, Liu Z, Zhang H, Zhao Q, Wang M, Dong H, Zhang Z
International journal of molecular medicine 2019 May;43(5):1979-1990

CSRP3 mediates polyphenols-induced cardioprotection in hypertension.

Oudot C, Gomes A, Nicolas V, Le Gall M, Chaffey P, Broussard C, Calamita G, Mastrodonato M, Gena P, Perfettini JL, Hamelin J, Lemoine A, Fischmeister R, Vieira HLA, Santos CN, Brenner C
The Journal of nutritional biochemistry 2019 Apr;66:29-42

Downregulation of Aquaporins (AQP1 and AQP5) and Na,K-ATPase in Porcine Reproductive and Respiratory Syndrome Virus-Infected Pig Lungs.

Zhang J, Yan M, Gu W, Chen A, Liu J, Li L, Zhang S, Liu G
Inflammation 2018 Jun;41(3):1104-1114

Wnt4 is significantly upregulated during the early phases of cisplatin-induced acute kidney injury.

He YX, Diao TT, Song SM, Wang CC, Wang Y, Zhou CL, Bai YB, Yu SS, Mi X, Yang XY, Wei QJ, Li B
Scientific reports 2018 Jul 12;8(1):10555

A novel histochemical method of simultaneous detection by a single- or double-immunofluorescence and Bielschowsky's silver staining in teased rat sciatic nerves.

Segura-Anaya E, Flores-Miranda R, Martínez-Gómez A, Dent MAR
Journal of neuroscience methods 2018 Jul 1;304:46-51

Leucine rich α-2 glycoprotein is a potential urinary biomarker for renal tubular injury.

Lee H, Fujimoto M, Ohkawara T, Honda H, Serada S, Terada Y, Naka T
Biochemical and biophysical research communications 2018 Apr 15;498(4):1045-1051

A novel IL-1RA-PEP fusion protein with enhanced brain penetration ameliorates cerebral ischemia-reperfusion injury by inhibition of oxidative stress and neuroinflammation.

Zhang DD, Zou MJ, Zhang YT, Fu WL, Xu T, Wang JX, Xia WR, Huang ZG, Gan XD, Zhu XM, Xu DG
Experimental neurology 2017 Nov;297:1-13

Discovery of Aquaporin-1 and Aquaporin-4 Expression in an Intramedullary Spinal Cord Ependymal Cyst: Case Report.

Shepard MJ, Padmanaban V, Edwards NA, Chittiboina P, Ray-Chaudhury A, Heiss JD
World neurosurgery 2017 Nov;107:1046.e1-1046.e7

Direct visualization of the arterial wall water permeability barrier using CARS microscopy.

Lucotte BM, Powell C, Knutson JR, Combs CA, Malide D, Yu ZX, Knepper M, Patel KD, Pielach A, Johnson E, Borysova L, Dora KA, Balaban RS
Proceedings of the National Academy of Sciences of the United States of America 2017 May 2;114(18):4805-4810

Emodin ameliorates acute lung injury induced by severe acute pancreatitis through the up-regulated expressions of AQP1 and AQP5 in lung.

Xu J, Huang B, Wang Y, Tong C, Xie P, Fan R, Gao Z
Clinical and experimental pharmacology & physiology 2016 Nov;43(11):1071-1079

Kidney-specific knockout of Sav1 in the mouse promotes hyperproliferation of renal tubular epithelium through suppression of the Hippo pathway.

Kai T, Tsukamoto Y, Hijiya N, Tokunaga A, Nakada C, Uchida T, Daa T, Iha H, Takahashi M, Nomura T, Sato F, Mimata H, Ikawa M, Seto M, Matsuura K, Moriyama M
The Journal of pathology 2016 May;239(1):97-108

Stromal-Based Signatures for the Classification of Gastric Cancer.

Uhlik MT, Liu J, Falcon BL, Iyer S, Stewart J, Celikkaya H, O'Mahony M, Sevinsky C, Lowes C, Douglass L, Jeffries C, Bodenmiller D, Chintharlapalli S, Fischl A, Gerald D, Xue Q, Lee JY, Santamaria-Pang A, Al-Kofahi Y, Sui Y, Desai K, Doman T, Aggarwal A, Carter JH, Pytowski B, Jaminet SC, Ginty F, Nasir A, Nagy JA, Dvorak HF, Benjamin LE
Cancer research 2016 May 1;76(9):2573-86

Comparative morphological evaluation of domestic animal cornea.

Nautscher N, Bauer A, Steffl M, Amselgruber WM
Veterinary ophthalmology 2016 Jul;19(4):297-304

Localization of aquaporin 1 water channel in the Schmidt-Lanterman incisures and the paranodal regions of the rat sciatic nerve.

Segura-Anaya E, Martínez-Gómez A, Dent MA
Neuroscience 2015 Jan 29;285:119-27

Traditional Chinese medicine, Qing Ying Tang, ameliorates the severity of acute lung injury induced by severe acute pancreatitis in rats via the upregulation of aquaporin-1.

Gao Z, Xu J, Sun D, Zhang R, Liang R, Wang L, Fan R
Experimental and therapeutic medicine 2014 Dec;8(6):1819-1824

Proteomic analysis of podocyte exosome-enriched fraction from normal human urine.

Prunotto M, Farina A, Lane L, Pernin A, Schifferli J, Hochstrasser DF, Lescuyer P, Moll S
Journal of proteomics 2013 Apr 26;82:193-229

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Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: human skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 20333-1-AP(AQP1 antibody) at dilution of 1:1000
Sample type: tissue

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: Immunohistochemical of paraffin-embedded human kidney using 20333-1-AP(AQP1 antibody) at dilution of 1:100 (under 10x lens)
Sample type: tissue

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: The AQP1 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human AQP1. This antibody recognizes human,mouse,rat antigen. The AQP1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
Appendix: 20333-1-AP.pdf

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