17329-1-AP

antibody from Proteintech Group

Targeting: KRT20 CK20, K20, MGC35423

Provider product page for 17329-1-AP

Western blot

ELISA

Immunocytochemistry

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [12]
Comments [0]
Validations
Western blot [1]
Immunocytochemistry [1]
Immunohistochemistry [2]

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Product number: 17329-1-AP - Provider product page
Provider: Proteintech Group
Proper citation: Proteintech Cat#17329-1-AP, RRID:AB_2133592
Product name: Cytokeratin 20 antibody
Antibody type: Polyclonal
Description: Cytokeratin 20 antibody (Cat. #17329-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB, ELISA.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

KRT20 protein structure - 17329-1-AP shown in red.

Submitted references Propolis Has an Anticancer Effect on Early Stage Colorectal Cancer by Affecting Epithelial Differentiation and Gut Immunity in the Tumor Microenvironment.

Shen MH, Liu CY, Chang KW, Lai CL, Chang SC, Huang CJ
Nutrients 2023 Oct 24;15(21)

Single-cell transcriptomics uncovers EGFR signaling-mediated gastric progenitor cell differentiation in stomach homeostasis.

Takada H, Sasagawa Y, Yoshimura M, Tanaka K, Iwayama Y, Hayashi T, Isomura-Matoba A, Nikaido I, Kurisaki A
Nature communications 2023 Jun 29;14(1):3750

Establishment and characterization of an immortalized epithelial cell line from human gallbladder.

Wang Z, Wang S, Jia Z, Zhao Y, Yang M, Yan W, Chen T, Xiang D, Shao R, Liu Y
Frontiers in oncology 2022;12:994087

Gut microbiota drives macrophage-dependent self-renewal of intestinal stem cells via niche enteric serotonergic neurons.

Zhu P, Lu T, Wu J, Fan D, Liu B, Zhu X, Guo H, Du Y, Liu F, Tian Y, Fan Z
Cell research 2022 Jun;32(6):555-569

5-hydroxytryptamine produced by enteric serotonergic neurons initiates colorectal cancer stem cell self-renewal and tumorigenesis.

Zhu P, Lu T, Chen Z, Liu B, Fan D, Li C, Wu J, He L, Zhu X, Du Y, Tian Y, Fan Z
Neuron 2022 Jul 20;110(14):2268-2282.e4

LGR4 cooperates with PrPc to endow the stemness of colorectal cancer stem cells contributing to tumorigenesis and liver metastasis.

Cheng Q, Zheng H, Li M, Wang H, Guo X, Zheng Z, Chen C, Liu J, Zhan T, Li Z, Wu H, Han J, Liu L, Tang T, Chen Q, Du L
Cancer letters 2022 Aug 1;540:215725

Identification of cis-HOX-HOXC10 axis as a therapeutic target for colorectal tumor-initiating cells without APC mutations.

Chen Z, Wu J, Liu B, Zhang G, Wang Z, Zhang L, Wang K, Fan Z, Zhu P
Cell reports 2021 Jul 27;36(4):109431

IL-13 secreted by ILC2s promotes the self-renewal of intestinal stem cells through circular RNA circPan3.

Zhu P, Zhu X, Wu J, He L, Lu T, Wang Y, Liu B, Ye B, Sun L, Fan D, Wang J, Yang L, Qin X, Du Y, Li C, He L, Ren W, Wu X, Tian Y, Fan Z
Nature immunology 2019 Feb;20(2):183-194

LncGata6 maintains stemness of intestinal stem cells and promotes intestinal tumorigenesis.

Zhu P, Wu J, Wang Y, Zhu X, Lu T, Liu B, He L, Ye B, Wang S, Meng S, Fan D, Wang J, Yang L, Qin X, Du Y, Li C, He L, Ren W, Wu X, Tian Y, Fan Z
Nature cell biology 2018 Oct;20(10):1134-1144

A microengineered collagen scaffold for generating a polarized crypt-villus architecture of human small intestinal epithelium.

Wang Y, Gunasekara DB, Reed MI, DiSalvo M, Bultman SJ, Sims CE, Magness ST, Allbritton NL
Biomaterials 2017 Jun;128:44-55

DC - SIGNR by influencing the lncRNA HNRNPKP2 upregulates the expression of CXCR4 in gastric cancer liver metastasis.

Zhang Y, Zhang Q, Zhang M, Yuan M, Wang Z, Zhang J, Zhou X, Zhang Y, Lin F, Na H, Ren S, Zuo Y
Molecular cancer 2017 Apr 13;16(1):78

Urothelial Defects from Targeted Inactivation of Exocyst Sec10 in Mice Cause Ureteropelvic Junction Obstructions.

Fogelgren B, Polgar N, Lui VH, Lee AJ, Tamashiro KK, Napoli JA, Walton CB, Zuo X, Lipschutz JH
PloS one 2015;10(6):e0129346

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Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: COLO 320 cells were subjected to SDS PAGE followed by western blot with 17329-1-AP(KRT20 antibody) at dilution of 1:1500
Sample type: cell line

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: The Cytokeratin 20 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Cytokeratin 20. This antibody recognizes human,mouse,rat antigen. The Cytokeratin 20 antibody has been validated for the following applications: ELISA, WB, IHC, IF analysis.
Appendix: 17329-1-AP.pdf

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Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: Immunohistochemical of paraffin-embedded human colon cancer using 17329-1-AP(KRT20 antibody) at dilution of 1:100 (under 10x lens)
Sample type: tissue

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: Immunohistochemical of paraffin-embedded human colon cancer using 17329-1-AP(KRT20 antibody) at dilution of 1:100 (under 40x lens)
Sample type: tissue