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Learn10591-1-AP
antibody from Proteintech Group
Targeting: APOBEC3C
APOBEC1L, ARDC2, ARDC4, ARP5, bK150C2.3, PBI
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [16]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 10591-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10591-1-AP, RRID:AB_2057393
- Product name
- APOBEC3C antibody
- Antibody type
- Polyclonal
- Description
- APOBEC3C antibody (Cat. #10591-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references APOBEC3C coordinates DDX5 in R-loop resolution and dynamic control of Chk1-mediated stress-responsive circuitry as a prerequisite for gemcitabine resistance in p53-deficient cells.
A scalable two-step genome editing strategy for generating full-length gene-humanized mice at diverse genomic loci.
Effects of thymidylate synthase inhibitors differ in genomic uracilation and mutagenic potential.
Pan-cancer analysis and experimental validation revealed that prognostic biomarker APOBEC3C may promote M2-type macrophage polarization and prevent R-loop accumulation in glioma.
Characterization of RNA editing gene APOBEC3C as a candidate tumor suppressor in prostate cancer.
The role of APOBEC3C in modulating the tumor microenvironment and stemness properties of glioma: evidence from pancancer analysis.
APOBEC3 degradation is the primary function of HIV-1 Vif for virus replication in the myeloid cell line THP-1.
Actin-related protein 5 suppresses the cooperative activation of cardiac gene transcription by myocardin and MEF2.
APOBEC3 degradation is the primary function of HIV-1 Vif determining virion infectivity in the myeloid cell line THP-1.
Loss of SYNCRIP unleashes APOBEC-driven mutagenesis, tumor heterogeneity, and AR-targeted therapy resistance in prostate cancer.
Aberrant APOBEC3C expression induces characteristic genomic instability in pancreatic ductal adenocarcinoma.
Infection of Bronchial Epithelial Cells by the Human Adenoviruses A12, B3, and C2 Differently Regulates the Innate Antiviral Effector APOBEC3B.
APOBEC3A catalyzes mutation and drives carcinogenesis in vivo.
Enterovirus 71 antagonizes the inhibition of the host intrinsic antiviral factor A3G.
Expression and subcellular localisation of AID and APOBEC3 in adenoid and palatine tonsils.
Natural APOBEC3C variants can elicit differential HIV-1 restriction activity.
Tao L, Zhao Y, Jiang Z, Kong S, Ding Y, Ni T, Wang W, Liu Y
Cell death & disease 2026 Jan 7;17(1):6
Cell death & disease 2026 Jan 7;17(1):6
A scalable two-step genome editing strategy for generating full-length gene-humanized mice at diverse genomic loci.
Taguchi J, Kikuchi M, Jeon H, Shimizu R, Mori H, Ikawa M, Yamada Y, Sato K, Ikeda T, Yamazaki S, Ozawa M
Nature communications 2026 Jan 14;17(1):356
Nature communications 2026 Jan 14;17(1):356
Effects of thymidylate synthase inhibitors differ in genomic uracilation and mutagenic potential.
Holub E, Papp G, Pálinkás HL, Szajkó MB, Izrael R, Róna G, Vértessy BG, Békési A
Life science alliance 2026 Apr;9(4)
Life science alliance 2026 Apr;9(4)
Pan-cancer analysis and experimental validation revealed that prognostic biomarker APOBEC3C may promote M2-type macrophage polarization and prevent R-loop accumulation in glioma.
Yin W, Kuang Y, Xin Z, Huang H, Cao Y, Liu W, Wang L, Ren C, Jiang X
International journal of biological macromolecules 2025 Sep;322(Pt 1):146490
International journal of biological macromolecules 2025 Sep;322(Pt 1):146490
Characterization of RNA editing gene APOBEC3C as a candidate tumor suppressor in prostate cancer.
Wang LY, Shi J, Wang MF, Liu YM, Guo HS, Wang JC, Jiang S, Liang JQ, Liao XH, Chen SY
Scientific reports 2025 May 22;15(1):17725
Scientific reports 2025 May 22;15(1):17725
The role of APOBEC3C in modulating the tumor microenvironment and stemness properties of glioma: evidence from pancancer analysis.
Zhang S, Guo Y, Hu Y, Gao X, Bai F, Ding Q, Hou K, Wang Z, Sun X, Zhao H, Qu Z, Xu Q
Frontiers in immunology 2023;14:1242972
Frontiers in immunology 2023;14:1242972
APOBEC3 degradation is the primary function of HIV-1 Vif for virus replication in the myeloid cell line THP-1.
Ikeda T, Shimizu R, Nasser H, Carpenter MA, Cheng AZ, Brown WL, Sauter D, Harris RS
bioRxiv : the preprint server for biology 2023 Mar 29;
bioRxiv : the preprint server for biology 2023 Mar 29;
Actin-related protein 5 suppresses the cooperative activation of cardiac gene transcription by myocardin and MEF2.
Morita T, Hayashi K
FEBS open bio 2023 Feb;13(2):363-379
FEBS open bio 2023 Feb;13(2):363-379
APOBEC3 degradation is the primary function of HIV-1 Vif determining virion infectivity in the myeloid cell line THP-1.
Ikeda T, Shimizu R, Nasser H, Carpenter MA, Cheng AZ, Brown WL, Sauter D, Harris RS
mBio 2023 Aug 31;14(4):e0078223
mBio 2023 Aug 31;14(4):e0078223
Loss of SYNCRIP unleashes APOBEC-driven mutagenesis, tumor heterogeneity, and AR-targeted therapy resistance in prostate cancer.
Li X, Wang Y, Deng S, Zhu G, Wang C, Johnson NA, Zhang Z, Tirado CR, Xu Y, Metang LA, Gonzalez J, Mukherji A, Ye J, Yang Y, Peng W, Tang Y, Hofstad M, Xie Z, Yoon H, Chen L, Liu X, Chen S, Zhu H, Strand D, Liang H, Raj G, He HH, Mendell JT, Li B, Wang T, Mu P
Cancer cell 2023 Aug 14;41(8):1427-1449.e12
Cancer cell 2023 Aug 14;41(8):1427-1449.e12
Aberrant APOBEC3C expression induces characteristic genomic instability in pancreatic ductal adenocarcinoma.
Qian Y, Gong Y, Zou X, Liu Y, Chen Y, Wang R, Dai Z, Tasiheng Y, Lin X, Wang X, Luo G, Yu X, Cheng H, Liu C
Oncogenesis 2022 Jun 24;11(1):35
Oncogenesis 2022 Jun 24;11(1):35
Infection of Bronchial Epithelial Cells by the Human Adenoviruses A12, B3, and C2 Differently Regulates the Innate Antiviral Effector APOBEC3B.
Lejeune N, Poulain F, Willemart K, Blockx Z, Mathieu S, Gillet NA
Journal of virology 2021 Jun 10;95(13):e0241320
Journal of virology 2021 Jun 10;95(13):e0241320
APOBEC3A catalyzes mutation and drives carcinogenesis in vivo.
Law EK, Levin-Klein R, Jarvis MC, Kim H, Argyris PP, Carpenter MA, Starrett GJ, Temiz NA, Larson LK, Durfee C, Burns MB, Vogel RI, Stavrou S, Aguilera AN, Wagner S, Largaespada DA, Starr TK, Ross SR, Harris RS
The Journal of experimental medicine 2020 Dec 7;217(12)
The Journal of experimental medicine 2020 Dec 7;217(12)
Enterovirus 71 antagonizes the inhibition of the host intrinsic antiviral factor A3G.
Li Z, Ning S, Su X, Liu X, Wang H, Liu Y, Zheng W, Zheng B, Yu XF, Zhang W
Nucleic acids research 2018 Nov 30;46(21):11514-11527
Nucleic acids research 2018 Nov 30;46(21):11514-11527
Expression and subcellular localisation of AID and APOBEC3 in adenoid and palatine tonsils.
Seishima N, Kondo S, Wakae K, Wakisaka N, Kobayashi E, Kano M, Moriyama-Kita M, Nakanishi Y, Endo K, Imoto T, Ishikawa K, Sugimoto H, Hatano M, Ueno T, Koura M, Kitamura K, Muramatsu M, Yoshizaki T
Scientific reports 2018 Jan 17;8(1):918
Scientific reports 2018 Jan 17;8(1):918
Natural APOBEC3C variants can elicit differential HIV-1 restriction activity.
Anderson BD, Ikeda T, Moghadasi SA, Martin AS, Brown WL, Harris RS
Retrovirology 2018 Dec 17;15(1):78
Retrovirology 2018 Dec 17;15(1):78
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Human peripheral blood leukocyte cells were subjected to SDS PAGE followed by western blot with 10591-1-AP( APOBEC3C Antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The APOBEC3C antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human APOBEC3C. This antibody recognizes human antigen. The APOBEC3C antibody has been validated for the following applications: ELISA, IHC, WB analysis.
