Antibody data
- Antibody Data
- Antigen structure
- References [22]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
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Validation data
Reference
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- Product number
- 16520-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#16520-1-AP, RRID:AB_2292918
- Product name
- Desmin antibody
- Antibody type
- Polyclonal
- Description
- Desmin antibody (Cat. #16520-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references ESRRB Facilitates the Conversion of Trophoblast-Like Stem Cells From Induced Pluripotent Stem Cells by Directly Regulating CDX2.
Vitellogenin 2 promotes muscle development and stimulates the browning of white fat.
Podocyte apoptosis in diabetic nephropathy by BASP1 activation of the p53 pathway via WT1.
Dual Regeneration of Muscle and Nerve by Intramuscular Infusion of Mitochondria in a Nerve Crush Injury Model.
Clinical trajectory of a patient with filaminopathy who developed arrhythmogenic cardiomyopathy, myofibrillar myopathy, and multiorgan tumors.
BMP9 attenuates occurrence of venous malformation by maintaining endothelial quiescence and strengthening vessel walls via SMAD1/5/ID1/α-SMA pathway.
Neointimal hyperplasia in the inferior vena cava of adenine-induced chronic kidney disease rats with aortocaval fistulas.
TRAF6 Activates Fibroblasts to Cancer-Associated Fibroblasts through FGF19 in Tumor Microenvironment to Benefit the Malignant Phenotype of Melanoma Cells.
Multimeric conformation of type III intermediate filaments but not the filamentous conformation exhibits high affinity to lipid bilayers.
Effect of sarcolipin-mediated cell transdifferentiation in sarcopenia-associated skeletal muscle fibrosis.
miR-193a/b-3p relieves hepatic fibrosis and restrains proliferation and activation of hepatic stellate cells.
Molecular network of miR-1343 regulates the pluripotency of porcine pluripotent stem cells via repressing OTX2 expression.
Yes-associated protein regulates podocyte cell cycle re-entry and dedifferentiation in adriamycin-induced nephropathy.
Protein phosphatase 2A modulates podocyte maturation and glomerular functional integrity in mice.
Zhen-wu-tang protects against podocyte injury in rats with IgA nephropathy via PPARγ/NF-κB pathway.
Interleukin-17A participates in podocyte injury by inducing IL-1β secretion through ROS-NLRP3 inflammasome-caspase-1 pathway.
miR-17-3p Contributes to Exercise-Induced Cardiac Growth and Protects against Myocardial Ischemia-Reperfusion Injury.
Nicotine facilitates VSMC dysfunction through a miR-200b/RhoGDIA/cytoskeleton module.
Improved neurological outcome by intramuscular injection of human amniotic fluid derived stem cells in a muscle denervation model.
MiR-146a-5p suppresses activation and proliferation of hepatic stellate cells in nonalcoholic fibrosing steatohepatitis through directly targeting Wnt1 and Wnt5a.
MAD2B contributes to podocyte injury of diabetic nephropathy via inducing cyclin B1 and Skp2 accumulation.
Effects of asiaticoside on levels of podocyte cytoskeletal proteins and renal slit diaphragm proteins in adriamycin-induced rat nephropathy.
Yu S, Zhang R, Shen Q, Zhu Z, Zhang J, Wu X, Zhao W, Li N, Yang F, Wei H, Hua J
Frontiers in cell and developmental biology 2021;9:712224
Frontiers in cell and developmental biology 2021;9:712224
Vitellogenin 2 promotes muscle development and stimulates the browning of white fat.
Li Y, Sun X, Bai Y, Ji Y, Ren H, Yu X, Yan Y, He X, Dong Y, Zhang L, Luo X, Wang H
Aging 2021 Oct 5;13(19):22985-23003
Aging 2021 Oct 5;13(19):22985-23003
Podocyte apoptosis in diabetic nephropathy by BASP1 activation of the p53 pathway via WT1.
Zhang Y, Xu C, Ye Q, Tong L, Jiang H, Zhu X, Huang L, Lin W, Fu H, Wang J, Persson PB, Lai EY, Mao J
Acta physiologica (Oxford, England) 2021 May;232(1):e13634
Acta physiologica (Oxford, England) 2021 May;232(1):e13634
Dual Regeneration of Muscle and Nerve by Intramuscular Infusion of Mitochondria in a Nerve Crush Injury Model.
Sheu ML, Shen CC, Tsou HK, Yang MY, Su HL, Sheehan J, Chang MH, Chen HS, Pan HC
Neurosurgery 2021 Jun 15;89(1):E49-E59
Neurosurgery 2021 Jun 15;89(1):E49-E59
Clinical trajectory of a patient with filaminopathy who developed arrhythmogenic cardiomyopathy, myofibrillar myopathy, and multiorgan tumors.
Matsumura T, Inoue K, Toyooka K, Inoue M, Iida A, Saito Y, Nishikawa T, Moriuchi K, Beck G, Nishino I, Fujimura H
Neuromuscular disorders : NMD 2021 Dec;31(12):1282-1286
Neuromuscular disorders : NMD 2021 Dec;31(12):1282-1286
BMP9 attenuates occurrence of venous malformation by maintaining endothelial quiescence and strengthening vessel walls via SMAD1/5/ID1/α-SMA pathway.
Li Y, Shang Q, Li P, Yang Z, Yang J, Shi J, Ge S, Wang Y, Fan X, Jia R
Journal of molecular and cellular cardiology 2020 Oct;147:92-107
Journal of molecular and cellular cardiology 2020 Oct;147:92-107
Neointimal hyperplasia in the inferior vena cava of adenine-induced chronic kidney disease rats with aortocaval fistulas.
Du J, Liang L, Liu S, Yang X, Cao S, Zhang H, Su H, Gong X, Chen Q, Kong X, Xu D
Clinical and experimental nephrology 2020 Nov;24(11):1007-1014
Clinical and experimental nephrology 2020 Nov;24(11):1007-1014
TRAF6 Activates Fibroblasts to Cancer-Associated Fibroblasts through FGF19 in Tumor Microenvironment to Benefit the Malignant Phenotype of Melanoma Cells.
Guo Y, Zhang X, Zeng W, Zhang J, Cai L, Wu Z, Su J, Xiao Y, Liu N, Tang L, Xu X, Chen X, Peng C
The Journal of investigative dermatology 2020 Nov;140(11):2268-2279.e11
The Journal of investigative dermatology 2020 Nov;140(11):2268-2279.e11
Multimeric conformation of type III intermediate filaments but not the filamentous conformation exhibits high affinity to lipid bilayers.
Hwang B, Ise H
Genes to cells : devoted to molecular & cellular mechanisms 2020 Jun;25(6):413-426
Genes to cells : devoted to molecular & cellular mechanisms 2020 Jun;25(6):413-426
Effect of sarcolipin-mediated cell transdifferentiation in sarcopenia-associated skeletal muscle fibrosis.
Chen QN, Fan Z, Lyu AK, Wu J, Guo A, Yang YF, Chen JL, Xiao Q
Experimental cell research 2020 Apr 1;389(1):111890
Experimental cell research 2020 Apr 1;389(1):111890
miR-193a/b-3p relieves hepatic fibrosis and restrains proliferation and activation of hepatic stellate cells.
Ju B, Nie Y, Yang X, Wang X, Li F, Wang M, Wang C, Zhang H
Journal of cellular and molecular medicine 2019 Jun;23(6):3824-3832
Journal of cellular and molecular medicine 2019 Jun;23(6):3824-3832
Molecular network of miR-1343 regulates the pluripotency of porcine pluripotent stem cells via repressing OTX2 expression.
Xie Y, Cao H, Zhang Z, Zhang S, Wang H
RNA biology 2019 Jan;16(1):82-92
RNA biology 2019 Jan;16(1):82-92
Yes-associated protein regulates podocyte cell cycle re-entry and dedifferentiation in adriamycin-induced nephropathy.
Xie K, Xu C, Zhang M, Wang M, Min L, Qian C, Wang Q, Ni Z, Mou S, Dai H, Pang H, Gu L
Cell death & disease 2019 Dec 4;10(12):915
Cell death & disease 2019 Dec 4;10(12):915
Protein phosphatase 2A modulates podocyte maturation and glomerular functional integrity in mice.
Zhu X, Ye Y, Xu C, Gao C, Zhang Y, Zhou J, Lin W, Mao J
Cell communication and signaling : CCS 2019 Aug 6;17(1):91
Cell communication and signaling : CCS 2019 Aug 6;17(1):91
Zhen-wu-tang protects against podocyte injury in rats with IgA nephropathy via PPARγ/NF-κB pathway.
Liu B, He Y, Lu R, Zhou J, Bai L, Zhang P, Ye S, Wu J, Liang C, Zhou Y, Zhou J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 May;101:635-647
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 May;101:635-647
Interleukin-17A participates in podocyte injury by inducing IL-1β secretion through ROS-NLRP3 inflammasome-caspase-1 pathway.
Yan J, Li Y, Yang H, Zhang L, Yang B, Wang M, Li Q
Scandinavian journal of immunology 2018 Apr;87(4):e12645
Scandinavian journal of immunology 2018 Apr;87(4):e12645
miR-17-3p Contributes to Exercise-Induced Cardiac Growth and Protects against Myocardial Ischemia-Reperfusion Injury.
Shi J, Bei Y, Kong X, Liu X, Lei Z, Xu T, Wang H, Xuan Q, Chen P, Xu J, Che L, Liu H, Zhong J, Sluijter JP, Li X, Rosenzweig A, Xiao J
Theranostics 2017;7(3):664-676
Theranostics 2017;7(3):664-676
Nicotine facilitates VSMC dysfunction through a miR-200b/RhoGDIA/cytoskeleton module.
Liang D, Wang Z, Yan Z, Hou S, Xu W, Wang L, Shang M, Qiao Z
Scientific reports 2017 Mar 2;7:43798
Scientific reports 2017 Mar 2;7:43798
Improved neurological outcome by intramuscular injection of human amniotic fluid derived stem cells in a muscle denervation model.
Chen CJ, Cheng FC, Su HL, Sheu ML, Lu ZH, Chiang CY, Yang DY, Sheehan J, Pan HC
PloS one 2015;10(5):e0124624
PloS one 2015;10(5):e0124624
MiR-146a-5p suppresses activation and proliferation of hepatic stellate cells in nonalcoholic fibrosing steatohepatitis through directly targeting Wnt1 and Wnt5a.
Du J, Niu X, Wang Y, Kong L, Wang R, Zhang Y, Zhao S, Nan Y
Scientific reports 2015 Nov 5;5:16163
Scientific reports 2015 Nov 5;5:16163
MAD2B contributes to podocyte injury of diabetic nephropathy via inducing cyclin B1 and Skp2 accumulation.
Su H, Wan Q, Tian XJ, He FF, Gao P, Tang H, Ye C, Fan D, Chen S, Wang YM, Meng XF, Zhang C
American journal of physiology. Renal physiology 2015 Apr 1;308(7):F728-36
American journal of physiology. Renal physiology 2015 Apr 1;308(7):F728-36
Effects of asiaticoside on levels of podocyte cytoskeletal proteins and renal slit diaphragm proteins in adriamycin-induced rat nephropathy.
Wang Z, Liu J, Sun W
Life sciences 2013 Sep 3;93(8):352-8
Life sciences 2013 Sep 3;93(8):352-8
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse heart tissue were subjected to SDS PAGE followed by western blot with 16520-1-AP(DES antibody) at dilution of 1:4000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using DES antibody 16520-1-AP at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human heart using 16520-1-AP(DES antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human heart using 16520-1-AP(DES antibody) at dilution of 1:100 (under 40x lens)
- Sample type
- tissue