orb385939

antibody from Biorbyt
Targeting: DES CMD1I, CSM1, CSM2
Provider product page for orb385939
Western blot
Immunocytochemistry
Immunohistochemistry
Flow cytometry

Antibody data

Product number
orb385939 - Provider product page
Provider
Biorbyt
Product name
Desmin Antibody (Muscle cell marker)
Antibody type
Monoclonal
Description
Cytoskeletal intermediate filaments (IFs) constitute a diverse group of proteins that are expressed in a highly tissue-specific manner. IFs are constructed from two-chain a-helical coiled-coil molecules arranged on an imperfect helical lattice, and have been widely used as markers for distinguishing individual cell types within a tissue and identifying the origins of metastatic tumors. Vimentin is an IF general marker of cells originating in the mesenchyme. Vimentin and Desmin, a related class III IF, are both expressed during skeletal muscle development. Desmin, a 469 amino acid protein found near the Z line in sarcomeres, is expressed more frequently in adult differentiated state tissues. Anti-desmin detects cells of normal smooth, skeletal, and cardiac muscles. Antibody reacts with leiomyomas, leiomyosarcoma, rhabdomyomas, rhabdomyosarcoma, and perivascular cells of glomus tumors of the skin.
Reactivity
Human, Mouse, Rat
Host
Mouse
Conjugate
Unconjugated
Antibody clone number
DES/1711
Vial size
20 ug
Storage
Store the Desmin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
DES protein structure - orb385939 shown in red.