23935-1-AP

antibody from Proteintech Group

Targeting: GFAP FLJ45472

Provider product page for 23935-1-AP

Western blot

ELISA

Immunocytochemistry

Immunoprecipitation

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [23]
Comments [0]
Validations
Western blot [1]
Immunohistochemistry [1]

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Product number: 23935-1-AP - Provider product page
Provider: Proteintech Group
Product name: GFAP antibody
Antibody type: Polyclonal
Description: KD/KO validated GFAP antibody (Cat. #23935-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

GFAP protein structure - 23935-1-AP shown in red.

Submitted references CD146(+) pericyte-like lung cancer brain metastatic stem cells promote tumor angiogenesis through dual regulatory effects on the VEGF/VEGFR axis.

Liu W, Duan W, Xia S, Liu Y, Chu H, Liang K, Fang S, Lin M, Wei S, You X, Hu Q, Qi J, Wang Q
Theranostics 2026;16(4):1905-1924

Understanding Glioblastoma Dynamics Using 3D Organoids and Engineered Extracellular Matrix.

McManis A, Jimenez CA, Shirolkar A, Raza Ur Rehman S, Mallick S, Murphy M, Gaharwar AK, Singh I
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(24):e22926

Intermittent fasting protects MPTP-induced Parkinson's disease mouse model through regulating gut microbiota dysbiosis.

Qu Y, Wang P, Wang D, Li B, Yang F
International immunopharmacology 2026 Apr 15;175:116447

Effect of Fangxia-Dihuang Decoction on doxorubicin-induced cognitive impairment in breast cancer animal model.

Wang X, Sun Q, Li J, Lai B, Pei X, Chen N
Frontiers in oncology 2025;15:1515498

Understanding proneural-mesenchymal transition using patient-derived glioma stem-like cell (GSC) organoids and engineered extracellular matrix.

McManis A, Jimenez CA, Shirolkar A, Rehman SRU, Mallick S, Murphy M, Gaharwar AK, Singh I
bioRxiv : the preprint server for biology 2025 Sep 20;

RBM10 deficiency promotes brain metastasis by modulating sphingolipid metabolism in a BBB model of EGFR mutant lung adenocarcinoma.

Xu G, An B, Wang R, Pan B, Hao H, Ren X, Jing Z, Gao W, Li Y, Jin Y, Lin E, Shang L, Jia D, Yu Y
Journal of experimental & clinical cancer research : CR 2025 Mar 11;44(1):95

The mechanism of Yizhi Qingxin formula to improve neuroinflammation in Alzheimer's disease by regulating the TLR4/NF‑κB/NLRP3 pathway.

Chen WX, Huang QY, Sun JH, Yang XY, Pei H, Cao Y, Li H, Ma LN
Journal of Asian natural products research 2025 Aug 4;:1-19

Metabolic regulation of the glioblastoma stem cell epitranscriptome by malate dehydrogenase 2.

Lv D, Dixit D, Cruz AF, Kim LJY, Duan L, Xu X, Wu Q, Zhong C, Lu C, Gersey ZC, Gimple RC, Xie Q, Yang K, Liu X, Fang X, Wu X, Kidwell RL, Wang X, Bao S, He HH, Locasale JW, Agnihotri S, Rich JN
Cell metabolism 2024 Nov 5;36(11):2419-2436.e8

High Intraocular Concentration of Fibrinogen Regulates Retinal Function Via the ICAM-1 Pathway.

Sotani Y, Imai H, Yamada H, Miki A, Kusuhara S, Nakamura M
Investigative ophthalmology & visual science 2024 Nov 4;65(13):34

Tangeretin Attenuates Cerebral Ischemia-Reperfusion-Induced Neuronal Pyroptosis by Inhibiting AIM2 Inflammasome Activation via Regulating NRF2.

You G, Zheng L, Zhang Y, Zhang Y, Wang Y, Guo W, Liu H, Tatiana P, Vladimir K, Zan J
Inflammation 2024 Feb;47(1):145-158

Adenosine signalling to astrocytes coordinates brain metabolism and function.

Theparambil SM, Kopach O, Braga A, Nizari S, Hosford PS, Sagi-Kiss V, Hadjihambi A, Konstantinou C, Esteras N, Gutierrez Del Arroyo A, Ackland GL, Teschemacher AG, Dale N, Eckle T, Andrikopoulos P, Rusakov DA, Kasparov S, Gourine AV
Nature 2024 Aug;632(8023):139-146

Lethal adulthood myelin breakdown by oligodendrocyte-specific Ddx54 knockout.

Oizumi H, Miyamoto Y, Seiwa C, Yamamoto M, Yoshioka N, Iizuka S, Torii T, Ohbuchi K, Mizoguchi K, Yamauchi J, Asou H
iScience 2023 Oct 20;26(10):107448

Vitamin D(3) analogue calcipotriol inhibits the profibrotic effects of transforming growth factor- β1 on pancreatic stellate cells.

Zheng M, Li H, Gao Y, Brigstock DR, Gao R
European journal of pharmacology 2023 Oct 15;957:176000

Effect of Tanshinone IIA on Gut Microbiome in Diabetes-Induced Cognitive Impairment.

Zheng Y, Zhou X, Wang C, Zhang J, Chang D, Liu W, Zhu M, Zhuang S, Shi H, Wang X, Chen Y, Cheng Z, Lin Y, Nan L, Sun Y, Min L, Liu J, Chen J, Zhang J, Huang M
Frontiers in pharmacology 2022;13:890444

Insm1 promotes differentiation of retinal progenitor cells toward photoreceptor cells in the developing retina through up-regulation of SHH.

Zhou P, Xu Y, Yang L, Meng P, Guo J, Liu Z, Jin B, Xie K, Zhu H, Du L, Jin X
Journal of molecular histology 2022 Dec;53(6):947-954

Destructive Effects of Pyroptosis on Homeostasis of Neuron Survival Associated with the Dysfunctional BBB-Glymphatic System and Amyloid-Beta Accumulation after Cerebral Ischemia/Reperfusion in Rats.

Lyu Z, Chan Y, Li Q, Zhang Q, Liu K, Xiang J, Li X, Cai D, Li Y, Wang B, Yu Z
Neural plasticity 2021;2021:4504363

Maternal high sugar and fat diet benefits offspring brain function via targeting on the gut-brain axis.

Wang D, Zhang H, Zeng M, Tang X, Zhu X, Guo Y, Qi L, Xie Y, Zhang M, Chen D
Aging 2021 Mar 26;13(7):10240-10274

CGG repeat RNA G-quadruplexes interact with FMRpolyG to cause neuronal dysfunction in fragile X-related tremor/ataxia syndrome.

Asamitsu S, Yabuki Y, Ikenoshita S, Kawakubo K, Kawasaki M, Usuki S, Nakayama Y, Adachi K, Kugoh H, Ishii K, Matsuura T, Nanba E, Sugiyama H, Fukunaga K, Shioda N
Science advances 2021 Jan;7(3)

Characterization of Nef expression in different brain regions of SIV-infected macaques.

Yarandi SS, Robinson JA, Vakili S, Donadoni M, Burdo TH, Sariyer IK
PloS one 2020;15(11):e0241667

Identification and immunohistochemical characterization of G-quadruplexes in mouse brain.

Asamitsu S, Imai Y, Yabuki Y, Ikenoshita S, Takeuchi M, Kashiwagi H, Tanoue Y, Fukuda T, Shioda N
Biochemical and biophysical research communications 2020 Oct 8;531(1):67-74

Label-free classification of neurons and glia in neural stem cell cultures using a hyperspectral imaging microscopy combined with machine learning.

Ogi H, Moriwaki S, Kokubo M, Hikida Y, Itoh K
Scientific reports 2019 Jan 24;9(1):633

Effects of three-dimensional collagen scaffolds on the expression profiles and biological functions of glioma cells.

Jia W, Jiang X, Liu W, Wang L, Zhu B, Zhu H, Liu X, Zhong M, Xie D, Huang W, Jia W, Li S, Liu X, Zuo X, Cheng D, Dai J, Ren C
International journal of oncology 2018 Jun;52(6):1787-1800

Administration of molecular hydrogen during pregnancy improves behavioral abnormalities of offspring in a maternal immune activation model.

Imai K, Kotani T, Tsuda H, Nakano T, Ushida T, Iwase A, Nagai T, Toyokuni S, Suzumura A, Kikkawa F
Scientific reports 2018 Jun 15;8(1):9221

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Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: mouse brain tissue were subjected to SDS PAGE followed by western blot with 23935-1-AP(GFAP antibody) at dilution of 1:1000
Sample type: tissue

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: The GFAP antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human GFAP. This antibody recognizes human, mouse, rat antigen. The GFAP antibody has been validated for the following applications: ELISA, WB, IHC analysis.
Appendix: 23935-1-AP.pdf

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