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- Product number
- 16825-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#16825-1-AP, RRID:AB_2109646
- Product name
- GFAP antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated GFAP antibody (Cat. #16825-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Adenosine A(2A) receptors regulate D(2)-type medium spiny neurons in the nucleus accumbens to mediate pain and depression comorbidity.
Chronic intermittent hypoxia increases Parkinson's disease susceptibility via PPARα-mediated lipid droplet-mitochondrial dysfunction.
Flavonoids of Ziziphora clinopodioides improve Alzheimer's cognitive impairment and inhibit NLRP3 inflammasome activation via autophagy-lysosome pathway.
The C3-C3aR axis drives rotenone-induced cognitive damage via synaptic engulfment, dark microglia and PANoptosis.
Glaucine suppresses IL-16/CD4 to alleviate neuropathic pain via spinal p56(lck)-NMDA receptor signaling.
c-MAF Transcriptionally Activates Slc40a1 to Repress Ferroptosis in Sepsis-Associated Encephalopathy.
Early-life inflammation increases aggressive behavior in adult male mice through an astrocyte-neuron signaling.
DPEP2 suppresses hyperinflammation via metabolic reprogramming of macrophages in sepsis.
Reprogramming of neuronal genome function and phenotype by astrocytes.
Upregulation of T-type voltage-dependent Ca²⁺ channels in activated hepatic stellate cells promotes liver fibrosis in metabolic dysfunction-associated steatohepatitis.
Sphingosine-1-Phosphate Receptor 3 Mediated Neuroinflammation is Critically Involved in the Development of Brain Injury Following Cardiac Arrest in Mice.
A Ratiometric Afterglow Luminescence Probe for in Vivo Imaging of Neuroinflammation in Traumatic Brain Injury.
Blood-brain barrier-penetrative lipid nanoparticles enable systemic delivery of TRIM11 mRNA to disaggregate Tau in Alzheimer's disease models.
Adipose tissue-derived stromal cells enhance glycolytic metabolism in injured nerve cells via the FOXK1-HK2 axis for spinal cord injury repair.
Tanshinone IIA-pretreated mesenchymal stem cells alleviate neuroinflammation in 3×Tg-AD mice via the TREM2/PI3K/Akt pathway.
CRP Deficiency Rescues Periodontitis-Induced Hippocampal Neurogenesis Impairment by Suppressing OPC-Derived BMP4 Signaling in Rats.
Evodiamine alleviates MPTP-induced Parkinson's disease in mice by regulating gut microbiota and suppressing TLR4/MyD88/NF-kB pathway.
Roudoukou-Suanzaoren Ameliorates Chronic Restraint-Induced Anxiety- and Depression-Like Behaviors in Mice via the Gut-Brain Axis.
Mechanism of Qufeng Huoxue decoction in treating paclitaxel-induced peripheral neuropathy based on network pharmacology and molecular docking.
Enteric gliosis induced by TRPV4 alleviates intestinal excessive-motility through Ca(2+) signaling.
Triamcinolone acetonide nanoparticles ameliorate interstitial cystitis and anxiety/depression by targeting the bladder-metabolic-brain axis.
Electroacupuncture as a promising therapeutic strategy for chronic constriction injury-induced neuropathic pain: Insights into the PPARα/SIRT1/NF-κB axis.
Bufotenidine attenuates astrocyte ferroptosis in depressive-like behaviors through targeting GluA1 to reduce neuronal lipid synthesis.
STAT3 inhibition ameliorates cognitive dysfunction in type 2 diabetes mellitus by modulating astrocytes via Nrf2 pathway activation.
Modified Kai-Xin-San ameliorates cognitive impairment in Alzheimer's disease model mice by regulating neuroinflammation and synaptic dysfunction.
Sex-dependent impact of Il6 deficiency in Parkinson's disease mice.
Design, synthesis, and biological evaluation of pyranone-carbamate hybrids as selective butyrylcholinesterase inhibitors with anti-neuroinflammatory activity for Alzheimer's disease.
A mitochondria-targeted idebenone derivative W1a mitigates cerebral ischemia-reperfusion injury by preserving mitochondrial integrity and suppressing neuroinflammation.
BTLA-mediated regulation of neuroimmune responses enhances recovery after intracerebral hemorrhage.
Neuroprotective Effects of Desert Milk Exosomes in LPS-Induced Cognitive Decline: Role of Microglial M2 Polarization and AMPK Signaling.
Development of a Novel Extracellular Vesicle-Based Biomarker Approach for Pediatric High-Grade Glioma.
Glycyrrhizic acid-loaded biomimetic hybrid liposomes targeting inflammatory cascades and PD-1/PD-L1 pathway to reverse neuroinflammation-driven cognitive decline.
Astrocytic PYGM attenuates tau pathology by promoting lactate-mediated neuroprotection.
Adenylyl Cyclase 8 in Dorsal CA1 Neurons Prevents Depressive-Like Behaviors by Maintaining Neuronal Excitability and Glutamatergic Neurotransmission Through TIP39-PTH2R Signaling.
hsa_circ_0006168 drives microglial activation in TNC via miR-99b-5p/KDM6B axis to promote central sensitization in migraine.
Spatial memory in Alzheimer's disease 5XFAD mice is enhanced by XPO1 inhibitor KPT-330.
Cognitive and Motor Dysfunction in STXBP1 R406H Mice.
KANK4 Regulates CXCL16 Glycosylation Through TMEM260 to Modulate Microglial Activation in Sepsis-associated Encephalopathy.
Neonatal Spinal-Cord-Like Scaffold with Hierarchical Structural and Neurogenetic Microenvironments for Spinal Cord Injury Repair.
Degradation of LOX-1 via Neuronal Autophagy Alleviates Cerebral Ischemia/Reperfusion Injury in Mice.
CD300a Immunoreceptor Blocking Attenuates Neuronal Apoptosis by Regulating Efferocytosis and Promotes Hindlimb Functional Recovery after Acute Spinal Cord Injury in Mice.
Aquaporin-4-overexpressing mesenchymal stem cells promote neurological recovery after intracerebral hemorrhage by inhibiting TLR4/NF-κB signaling.
EGCG-loaded nanoparticles attenuate post-SAH white matter injury by targeting HO-1/S100A10 to suppress oxidative stress-induced reactive astrocytes.
Gut microbial ammonia as a mediator of PFOS neurotoxicity and its remediation by the flavonoid Icaritin.
Tianwang Buxin Pill improves cognitive function in APP/PS1 mice by reducing neuronal damage and regulating synaptic plasticity.
Aberrant histone acetylation and dysregulated synaptic plasticity in cognitive impairment induced by a high-methionine diet.
Intermittent theta-burst stimulation promotes neurovascular unit remodeling after ischemic stroke in a mouse model.
Neuro-bone-skin tri-regeneration via a microenvironment-responsive PRP-loaded chitosan hydrogel for traumatic brain injury therapy.
Dual-responsive PDA-HP hydrogel enables mitochondria-targeted mild photothermal therapy for spinal cord repair.
Microalgae-MOF integrated drug delivery system for cranial radiotherapy and chemotherapy-induced brain injury.
IMR-1 ameliorates perinatal LPS-induced brain injury by promoting the conversion of glial cells into neurons.
Electroacupuncture Stimulation of the Head Motor Area Alleviates Brain Cell Pyroptosis and Neurobehaviors in Stroke Rats Through the NF-κB/NLRP3 Signaling Axis.
KDM2B-PP1 Promotes Remyelination and Functional Recovery After Facial Nerve Injury.
Gypenosides ameliorate depression by modulating microglial state transition via the NLRP3/Caspase-1/ASC signaling pathway.
Sleep deprivation accelerates Parkinson's disease pathology by upregulating LAG3 in astrocytes and disrupting glymphatic system function.
Thalamic glutamatergic neurons regulate seizure onset and generalization in temporal lobe epilepsy.
Injectable Brain Extracellular Matrix Hydrogels Enhance Neuronal Migration and Functional Recovery After Intracerebral Hemorrhage.
Curcumin-enhanced elvitegravir therapy mitigates neuroinflammation and cognitive deficits in EcoHIV mice.
Comparisons of the Effects of Low- or High-Fat Diets Rich in Soybean Oil, Lard, and Tea Seed Oil on Markers of Blood-Brain Barrier and Neuroinflammation in Ovariectomized Mice.
Co-regulation of microglial subgroups in Alzheimer's amyloid pathology: Implications for diagnosis and drug development.
Astrocytic Ror2-induced imbalance in brain and gut homeostasis contributes to chronic post-thoracotomy pain.
Optineurin overexpression ameliorates neurodegeneration through regulating neuroinflammation and mitochondrial quality in a murine model of amyotrophic lateral sclerosis.
Baicalein ameliorates cognitive decline induced by chronic cerebral hypoperfusion through the SIRT1-mediated Notch1 pathway to improve angiogenesis and suppress neuroinflammation.
Polyphenol-rich Morus nigra L. extract mitigates neuroinflammation and cognitive impairment through gut-brain axis modulation in an Alzheimer's disease rat model.
The protective effect of Blautia coccoides in secondary injury of intracerebral hemorrhage.
Integrated proteomics analysis and network pharmacology to elucidate the mechanism of Zhilong Huoxue Tongyu Capsule alleviate hypertensive retinopathy in Ang II infusion mice model.
Biomimetic piezoelectric hydrogel system for energy metabolism reprogramming in spinal cord injury repair.
Mechanistic insights into the anti-depressant effect of quercetin: an integrated bibliometrics, bioinformatics, and animal experimentation.
The effect of ponicidin on CFA-induced chronic inflammatory pain and its mechanism based on network pharmacology and molecular docking.
miR-17-5p Regulates Astrocyte Activation Through Targeting Mfn2 to Improve Nerve Function in Rats With Spinal Cord Injury.
Phase-adapted metal ion supply for spinal cord repair with a Mg-Zn incorporated chimeric microsphere.
Novel "hot spring"-mimetic scaffolds for sequential neurovascular network reconstruction and osteoporosis reversion.
RNA-binding proteins mediate the maturation of chromatin topology during differentiation.
Madecassoside exerts anti-neurodegeneration effects in protein l-isoaspartyl methyltransferase deficient mice via targeting PRDX2-mediated oxidative stress and inflammation.
Lysophosphatidic acid receptor 5 in insular cortex as a potential analgesic target in neuropathic pain.
Nitration of Tyrosine Residue Y10 of Aβ(1-42) Ameliorates Aβ(1-42)-Induced Neurotoxicity and Memory Impairment In Vitro and In Vivo.
Irisin/FNDC5 Regulates Endothelial Function to Improve Post-Stroke-Induced Cognitive Dysfunction by Stimulating AMPK-eNOS Signaling.
A Myelin Debris Cleaner for Spinal Cord Injury Recovery: Polycaprolactone / Cell Membrane Assembled Scaffolds.
Isoacteoside alleviates LPS-induced depressive-like behaviors in mice by inhibiting neuroinflammation through regulating microglial polarization and oxidative stress.
MSCs-EXOs containing miR-21a-5p promoted cell proliferation in the rat retinal Müller cell rMC-1 via targeting LATS1.
Neurotoxicity, α-synuclein pathology, and mitochondrial dysfunction: A comparative study of different mouse models of Parkinson's disease.
Transcription factor RUNX2 participates in astrocyte-mediated neuropathic pain via transcriptional activation of Ccl2.
Transplanting neural stem cells overexpressing miRNA-21 can promote neural recovery after cerebral hemorrhage through the SOX2/LIN28-let-7 signaling pathway.
Hypoxia preconditioned MSC exosomes attenuate high-altitude cerebral edema via the miR-125a-5p/RTEF-1 axis to protect vascular endothelial cells.
Tailoring the therapeutic potential of stem cell spheroid-derived decellularized ECM through post-decellularization BDNF incorporation to enhance brain repair.
GSDME-dependent astrocyte pyroptosis promotes the progression of neuroinflammation in experimental cerebral malaria.
TSP50 in Neural Stem Cells Regulates Aging-Related Cognitive Decline and Neuroinflammation by Altering the Gut Microbiota.
TRPC6 suppresses liver fibrosis by inhibiting hepatic stellate cell activation via CaMK4-CREB pathway.
PPARα-Mediated Fatty Acid Catabolism in Astrocytes Was Involved in Improvement of Cognitive Dysfunction by Phlorizin in APP/PS1 Mice.
Cerebrospinal fluid extracellular vesicle-derived miR-9-3p in spinal cord injury with neuroprotective implications and biomarker development.
CMTM6 drives glioblastoma progression by promoting M2 polarization and suppressing antigen presentation in microglia/macrophages.
Non-Competitive AMPA Receptor Antagonist Perampanel Inhibits Ischemia-Induced Neurodegeneration and Behavioral Deficits in Focal Cortical Pial Vessel Disruption Stroke Model.
Ursolic acid improves cognitive impairment in type 2 diabetic mice by preventing complement 3 secretion and neuropathy.
Enriched environment ameliorates neurobehavioral abnormalities, hippocampal inflammation, and synaptic dysfunction in adult male mice exposed to intermittent hypoxia during pregnancy.
Exosome derived from bone marrow derived mesenchymal stem cells prevents LPS-induced depressive like behaviors.
Lactylation-induced ALKBH5 targets RNF123 to worsen retinal Müller cell activation through PKM2-regulated Glycolysis in diabetic retinopathy.
Mechanism of retinal angiogenesis induced by HIF-1α and HIF-2α under hyperoxic conditions.
Innate immune sensing of Z-nucleic acids by ZBP1-RIPK1 axis drives neuroinflammation in Alzheimer's disease.
Disulfide-Appended siRNA Nanoeyedrops: Noninvasive Gene Therapy for Targeting Retinal Angiogenesis.
Comprehensive profiling of transcription factors for reprogramming human astrocytes to neuronal cells through endogenous CRISPR-based gene activation.
Engineered extracellular vesicles for targeted FGF20 delivery enhance neuroplasticity and functional recovery in ischemic stroke.
Picroside II Alleviates the Progression of Alzheimer's Disease via the NLRP3/Caspase-1/GSDMD Pathway.
Identification of disease-associated molecular signatures in the Prp-TDP-43A315T mouse model of ALS: Toward preclinical biomarker development.
Isocucurbitacin B inhibits gliomas through the promotion of anoikis by targeting caveolin 1.
CircFGFR2 induces astrocyte pyroptosis to promote ischemic stroke.
Long noncoding RNA NONRATT007487.2 drives cancer-induced bone pain progression through direct interaction with CXCL1.
NPB-1575 attenuates neuroinflammation and resists ferroptosis in rat ischemic stroke via IRS2 signaling pathway.
Artemisinin Alleviates Chronic Social Defeat Stress-Induced Depressive-Like Behavior by Inhibiting Neuroinflammation via the TLR4/MyD88/NF-κB/NLRP3 Signaling Pathway.
Icariside II Ameliorates Depression Induced by High-Fat Diet via the Microbiota-Gut-Brain Axis in Mice.
Flexible Living Artificial Dura Mater for Efficient Therapy of Central Nervous System Injury Based on Neuronal Differentiation and Neuroprotective A2 Astrocyte Activation.
Astrocyte-microglia crosstalk in the hippocampus mediates cognitive impairments induced by chronic intermittent hypoxia.
Neuronutritional enhancement of antioxidant defense system through Nrf2/HO1/NQO1 axis in fibromyalgia.
Combination therapy with 3-Hydroxybenzaldehyde and Albendazole modulates mitochondrial protein expression in astrocytes after Angiostrongylus cantonensis infection.
Scorpion venom heat-resistant synthetic peptide improves cognitive dysfunction of APP/PS1 mice through microglial retromer complex.
METTL3 modulates bone Cancer pain via m(6)A-dependent JAK2/STAT3 activation in spinal astrocytes.
Chronic psychological stress-orchestrated glial-ILC3 circuit exacerbates intestinal inflammation and depression.
Ketone monoester alleviates cognitive impairment in a transgenic mouse model of Alzheimer's disease through innate immunological IFITM3 pathway.
Parylation dependent nuclear export of HMGB1 via exportin 1 contributes to morphine tolerance.
The GLP1R Agonist Semaglutide Inhibits Reactive Astrocytes and Enhances the Efficacy of Neural Stem Cell Transplantation Therapy in Parkinson's Disease Mice.
Hepatic acetyl-CoA metabolism modulates neuroinflammation and depression susceptibility via acetate.
Microglial activation drives neuronal dysregulation in alcohol-induced seizure susceptibility.
Parthenolide Exerts Protection against Hypoxic-Ischemic Brain Damage in Neonatal Rats by Inhibiting Perk-Mediated Endoplasmic Reticulum Stress.
Zexieyin formula attenuates Alzheimer's disease via suppressing A1 astrocyte activation: A serum pharmacochemistry and network pharmacology study.
Urolithin B promotes the functional recovery of spinal cord injury by alleviating neuroinflammation via the inhibition of NLRP3 signaling pathway.
Presence of Astrocytic S1R/5-HT1A Heterocomplex in the mPFC: A Putative Link to S1R Activation Mediated Faster Antidepressant-Like Effects.
Glial cells missing 1 triggers gliosis and angiogenesis after neonatal brain injury.
Neutralizing XCL1 Attenuates Brain Injury and Reduces Lymphocyte and Dendritic Cell Recruitment Following Intracerebral Hemorrhage in Mice.
Umbilical Cord Mesenchymal Stromal Cell-Derived Extracellular Vesicles Transfer CD59 to Astrocytes to Alleviate Complement-Dependent Cytotoxicity.
Inhibition of Neuroinflammation by Costunolide Attenuates Hypoxic-Ischemic Brain Damage via the PI3K/AKT Pathway in Neonatal Rats.
Osthole alleviates neuropathic pain by suppressing astrocytes activation and associated inflammatory responses via the PKCδ/TRPV4 signaling pathway.
Wuling San ameliorates cerebral ischemia-reperfusion injury via suppression of the TRPM2/NLRP3 pathway.
NR2A-Wnt-TLR2 signaling axis mediates neuronal mitochondrial dysfunction contributing to neuropathic pain induced by nerve injury in diabetic mice.
The compound (E)-2-(3,4-dihydroxystyryl)-3-hydroxy-4H-pyran-4-one alleviates neuroinflammation and cognitive impairment in a mouse model of Alzheimer's disease.
Single-Cell RNA Sequencing Uncovers Molecular Features Underlying the Disrupted Neurogenesis Following Traumatic Brain Injury.
Characterization of Dystrophin Dp71 Expression and Interaction Partners in Embryonic Brain Development: Implications for Duchenne/Becker Muscular Dystrophy.
Radiation Damage to a Three-Dimensional Hydrogel Model of the Brain Perivascular Niche.
Genetic mutation in HSF4 is associated with retinal degeneration in mice.
Astragalin actives autophagy and inhibits apoptosis of astrocytes in AD mice via down-regulating Fas/Fasl-VDAC1 pathway.
Astragalin alleviates lipopolysaccharide-induced depressive-like behavior in mice by preserving blood-brain barrier integrity and suppressing neuroinflammation.
Berbamine alleviates neuropathic pain via suppressing spinal TMEM34/SGK1/FOXO3 axis.
RACK7 Interacts with PRC2 Complex to Regulate Astrocyte Development.
NSAID-mediated cyclooxygenase inhibition disrupts ectodermal derivative formation in axolotl embryos.
Poliumoside Exhibits Neuroprotective Effects against Cerebral Ischemia-Reperfusion Injury by Relieving Microglia-Mediated Neuronal Damage and Astrocytic Activation.
Neutrophil Extracellular Traps Promote AIM2-Dependent Microglial Pyroptosis Following Stroke.
Neuronal Deletion of Tumor Susceptibility Gene 101 (Tsg101) Causes Rapid Apoptotic Loss of Hippocampal CA3 Neurons.
Galectin-3 activates microglia and promotes neurological impairment via NLRP3/pyroptosis pathway following traumatic brain injury.
Chemotactic Zn micromotor for treatment of high blood ammonia-associated hepatic encephalopathy.
Parvalbumin neurons mediate neurological phenotypes of anti-NMDAR encephalitis.
Elucidation of Dexmedetomidine-Induced Analgesic Tolerance Mechanisms in Neuropathic Pain With Modulation of SGK1, NR2A, and NR2B Expression via the Spinal SGK1/NF-κB Signalling Pathway.
Evaluation of cytoprotective effects of cannabidiol on neuroinflammation and neurogenesis process in rat offsprings.
Egln3 expression in microglia enhances the neuroinflammatory responses in Alzheimer's disease.
MicroRNA-204-5p Deficiency within the vmPFC Region Contributes to Neuroinflammation and Behavioral Disorders via the JAK2/STAT3 Signaling Pathway in Rats.
Indole-3-Propionic Acid Attenuates Neuroinflammation and Cognitive Deficits by Inhibiting the RAGE-JAK2-STAT3 Signaling Pathway.
Proteomic Profiling and Therapeutic Targeting of Oxidative Stress in Autoimmune Encephalitis.
Reprogramming of skin fibroblasts by 3D spheroid culture promotes peripheral nerve regeneration via the ID3/semaphorin7a pathway.
Role of FPR2 antagonism in alleviating social isolation-induced depression and protecting blood-brain barrier integrity.
Arsenic exposure induces neural cells senescence and abnormal lipid droplet accumulation leading to social memory impairment in mice.
Activation of NR2A-Wnt-TLR2 Signaling Axis in Satellite Glial Cells of the Dorsal Root Ganglion Contributes to Neuropathic Pain Induced by Nerve Injury in Diabetic Mice.
Conjugated therapy with coaxially printed neural stem cell-laden microfibers and umbilical cord mesenchymal stem cell derived exosomes on complete transactional spinal cord defects.
Glial inwardly rectifying potassium channel 4.1 regulates secretion of BDNF and GDNF via ERK1/2 MAP kinases in trigeminal neuropathic pain.
TMEM59 deficiency activates chaperone-mediated autophagy and ameliorates disease-like pathologies in tauopathy model mice.
Effects of intermittent theta burst stimulation on the inflammatory response and cerebral blood flow in promoting neurovascular repair after ischemic stroke.
Txnip/Trx Is a Potential Element in Regulating O-GlcNAc Modification in Photoreceptors to Alleviate Diabetic Retinopathy.
Visualization of P2X7 Receptors in Living Human Gliomas: An 18F-GSK1482160 PET Imaging and Neuropathology Study.
Butyrate improves abnormal sleep architecture in a Parkinson's disease mouse model via BDNF/TrkB signaling.
Dingzhen pills inhibit neuronal ferroptosis and neuroinflammation by inhibiting the cGAS-STING pathway for Parkinson's disease mice.
The Anti-Parkinsonian A2A Receptor Antagonist Istradefylline (KW-6002) Attenuates Behavioral Abnormalities, Neuroinflammation, and Neurodegeneration in Cerebral Ischemia: An Adenosinergic Signaling Link Between Stroke and Parkinson's Disease.
Excessive expression of progranulin leads to neurotoxicity rather than neuroprotection.
Exploring the dynamic pathogenesis of Parkinson's disease by case-control and longitudinal blood transcriptome analyses.
GABA-dependent microglial elimination of inhibitory synapses underlies neuronal hyperexcitability in epilepsy.
Anti-epileptic and gut-protective effects of trioctanoin and the critical role of gut microbiota in a mouse model of epilepsy.
Visualizing bulk autophagy in vivo by tagging endogenous LC3B.
Optimally Aligned Nerve Scaffolds with Sustained Astaxanthin Release Improve the Inflammatory Microenvironment through Mitophagy Activation.
Refined qingkailing attenuates reactive astrocytes and glial scar formation after ischemia stroke via the EGFR/PLCγ pathway.
High precision and cost-effective multiplex quantification of amyloid-β40, amyloid-β42, p181Tau, p217Tau, neurofilament light chain, and glial fibrillary acidic protein from plasma and serum.
Association of Hsa_circ_0059511 with the sensitivity of the temozolomide chemotherapeutic treatment in human glioma cells.
Cannabidiol ameliorates seizures and neuronal damage in ferric chloride-induced posttraumatic epilepsy by targeting TRPV1 channel.
Kai-Xin-San ameliorates fluoxetine-resistant depressive-like behaviors by modulating tryptophan-kynurenine metabolic homeostasis in a rodent model.
Role of astrocytic mu-opioid receptors of the ventrolateral periaqueductal gray in modulating anxiety-like responses.
Mild subcortical stroke induces widespread astrogliosis independent of microglia and age.
Botulinum toxin type A inhibits microglia pyroptosis by suppressing Cblb-mediated degradation of Pdlim1 to attenuate neuropathic pain.
Dopamine Alleviated Diabetic Retinal Neurodegeneration through Protecting Retinal Ganglion Cells from Ferroptosis via the Nrf2/HO‑1 Signaling Pathway.
Müller cells are activated in response to retinal outer nuclear layer degeneration in rats subjected to simulated weightlessness conditions.
A novel carbamate-based hybrid derivative with anti-neuroinflammatory properties as a selective butyrylcholinesterase inhibitor for Alzheimer's disease therapy.
N-methyl-D-aspartate Receptor Subunits 2A and 2B Mediate Connexins and Pannexins in the Trigeminal Ganglion Involved in Orofacial Inflammatory Allodynia during Temporomandibular Joint Inflammation.
Microspheres of stem cells from human exfoliated deciduous teeth exhibit superior pulp regeneration capacity.
Gypenoside XLIX alleviates sepsis-associated encephalopathy by targeting PPAR-α.
Cold atmospheric plasma-activated saline alleviates secondary injury post-SCI by inhibiting extracellular matrix remodeling and infiltration of proinflammatory macrophages.
Lactiplantibacillus plantarum SG5 inhibits neuroinflammation in MPTP-induced PD mice through GLP-1/PGC-1α pathway.
Magnolol acts as a neurorestorative agent in an A(β1‑42)‑induced mouse model of Alzheimer's disease.
Bioactive Peptide Hydrogel Scaffold with High Fluidity, Thermosensitivity, and Neurotropism in 3D Spatial Structure for Promoted Repair of Spinal Cord Injury.
An Optimized Decellularized Extracellular Matrix from Dental Pulp Stem Cell Sheets Promotes Axonal Regeneration by Multiple Modes in Spinal Cord Injury Rats.
Upregulation of delta opioid receptor by meningeal interleukin-10 prevents relapsing pain.
Astrocyte-neuron communication through the complement C3-C3aR pathway in Parkinson's disease.
Astragaloside IV plays a neuroprotective role by promoting PPARγ in cerebral ischemia-reperfusion rats.
The aqueous extract of Armadillidium vulgare Latreille alleviates neuropathic pain via inhibiting neuron-astrocyte crosstalk mediated by the IL-12-IFN-γ-IFNGR-CXCL10 pathway.
6-thioguanine inhibits EV71 replication by reducing BIRC3-mediated autophagy.
Trehalose enhances macrophage autophagy to promote myelin debris clearance after spinal cord injury.
Altered ATP13A2/PARK9 Levels Influence α-Synuclein Accumulation in Neurons via Phagocytosis and Secretion in Glial Cells.
Electrophysiology-based screening identifies neuronal HtrA serine peptidase 2 (HTRA2) as a synaptic plasticity regulator participating in tauopathy.
NLRP3 inhibitor alleviates glycemic variability-induced cognitive impairment in aged rats with type 2 diabetes mellitus.
Enhanced neural activity detection with microelectrode arrays modified by drug-loaded calcium alginate/chitosan hydrogel.
Blood glucose and β-hydroxybutyrate predict significant brain injury after hypoxia-ischemia in neonatal mice.
CircKat6b Mediates the Antidepressant Effect of Esketamine by Regulating Astrocyte Function.
DHA Improves neurodevelopmental abnormalities in offspring of gestational diabetes mellitus patients via the PPAR-γ/FATP4 pathway.
Microglia-Derived Vitamin D Binding Protein Mediates Synaptic Damage and Induces Depression by Binding to the Neuronal Receptor Megalin.
HSPA1A inhibits pyroptosis and neuroinflammation after spinal cord injury via DUSP1 inhibition of the MAPK signaling pathway.
Nasal mucosal mesenchymal stem cells promote repair of sciatic nerve injury in rats by modulating the inflammatory microenvironment.
A visual cortical-lateral posterior thalamic nucleus circuit regulates depressive-like behaviors in male mice.
Radiation damage to a three-dimensional hydrogel model of the brain perivascular niche.
Glutamatergic argonaute2 promotes the formation of the neurovascular unit in mice.
3-N-Butylphthalide alleviate Aβ-induced cellular senescence through the CDK2-pRB1-Caspase3 axis.
Nrf2 activator tertiary butylhydroquinone enhances neural stem cell differentiation and implantation in Alzheimer's disease by boosting mitochondrial function.
NSAID-mediated cyclooxygenase inhibition disrupts ectodermal derivative formation in axolotl embryos.
PD-1 Attenuates Neuropathic Pain by Ameliorating NLRP3 Inflammasome-Mediated Microglia Pyroptosis.
Multi-omics analysis delineates molecular signatures of spinal ependymal tumor.
Transglutaminase-2 Promotes Microglial Synaptic Phagocytosis and Ameliorates Epileptic Seizures by Inhibiting ABCA1 Ubiquitination.
The potential of taVNS in attenuating blood-brain barrier damage, promoting angiogenesis and improving impaired cognitive function in a rat model of vascular cognitive impairment and dementia by activating the Wnt7/β-catenin signaling pathway.
Dietary cholesterol impairs cognition via gut microbiota-derived deoxycholic acid in obese mice.
Metabolic Remodeling During the Early Phase of Spontaneous Seizure Emergence Highlights Hexosamine Biosynthetic Pathway Dysregulation in Temporal Lobe Epilepsy.
Pharmacokinetic and Pharmacodynamic Evaluation of PZ-2891, an Anti-Alzheimer's Disease Agonist of PANK2.
Soluble CSF1R alleviates microgliopathy in a CSF1R-related leukoencephalopathy (CRL) mouse model.
Microglia-specific interleukin-4 delivery by engineered extracellular vesicles restores inner blood-retinal barrier in diabetic retinopathy via GAS6-MERTK pathway.
Astroglial kappa opioid receptor-mediated reduction of glutamate exchanger xCT in the prelimbic cortex underlies chronic stress-induced depressive-like behaviors.
Promoting astrocyte-neuron triiodothyronine shuttling attenuates brain damage in neonatal hypoxic-ischemic encephalopathy.
Treadmill Exercise Modulates the Leptin/LepR/GSK-3β Signalling Pathway to Improve Leptin Sensitivity and Alleviate Neuroinflammation in High-Fat Diet-Fed APP/PS1 Mice.
Upregulating mTOR/S6 K Pathway by CASTOR1 Promotes Astrocyte Proliferation and Myelination in Gpam(-/-)-induced mouse model of cerebral palsy.
Inhibiting NLRP3 Inflammasome Activation to Alleviate Retinal Inflammation and Protect the Optic Nerve of OPTN(E50K)Mice.
Exploring the molecular mechanism of icariin improving spinal cord injury through network pharmacology combined with experimental verification.
Synergistic microglial modulation by laminarin-based platinum nanozymes for potential intracerebral hemorrhage therapy.
Electroacupuncture Improves Microglial Polarization Induced-Inflammation by Regulating the TGF-β/Smad-3 Signaling Pathway in Ischemic Stroke Mice.
The Role of the cGAS/STING Pathway in Arsenic-Induced Neurotoxicity: Insights from the Crosstalk Between Astrocytes and Neurons.
Targeting CDK1 inhibits Golgi apparatus stress-mediated neuroinflammation and neuronal apoptosis after intracerebral hemorrhage by modulating GRASP55 phosphorylation.
Sex-dependent behavioral and neuronal alterations in the F2 generation of a neurodevelopmental mouse model for schizophrenia.
Glycosides of Buyang Huanwu decoction alleviate cerebral infarction injury by inhibiting neuronal pyroptosis via astrocyte-derived exosomal miR-378b_L+1.
Activated Schwann cells promote tumor growth in colon cancer.
Preventive and therapeutic effects of Tanshinone IIA on spinal cord injury without radiographic abnormality by regulating microglial phenotype polarization.
Cyclooxygenase-1 deletion in 5 × FAD mice protects against microglia-induced neuroinflammation and mitigates cognitive impairment.
Cerebral blood flow in elastin haploinsufficient and 3xTg-AD mice.
An ancient enhancer rapidly evolving in the human lineage promotes neural development and cognitive flexibility.
FGF21 Alleviates Hypoxic-Ischemic White Matter Injury in Neonatal Mice by Mediating Inflammation and Oxidative Stress Through PPAR-γ Signaling Pathway.
RvE1/ChemR23 facilitates hematoma clearance and promotes M2 polarization of macrophages/microglia in intracerebral hemorrhage.
Targeted sonodynamic therapy induces tumor cell quasi-immunogenic ferroptosis and macrophage immunostimulatory autophagy in glioblastoma.
Recombinant human heavy-chain ferritin nanoparticles loaded with rosuvastatin attenuates secondary brain injury in intracerebral hemorrhage.
Shuangxia Decoction attenuates sleep disruption in 5×FAD mice through neuroinflammation inhibition: An integrative analysis of transcriptomic and molecular biology investigations.
Macrophage migration inhibitory factor in the mouse hippocampus promotes neuroinflammation and cognitive dysfunction following anesthesia and surgery.
Melatonin alleviates retinal injury induced by vigabatrin and partially enhances its antiepileptic effects.
Pkd2l1 deletion inhibits the neurogenesis of cerebrospinal fluid-contacting neurons and impedes spinal cord injury repair.
Luteolin attenuates cadmium neurotoxicity by suppressing glial inflammation and supporting neuronal survival.
Anxiolytic effects of accelerated continuous theta burst stimulation on mice exposed to chronic restraint stress and the underlying mechanism involving gut microbiota.
VEGF secreted by human dental pulp stem cell promotes spinal cord injury repair by inhibiting microglial pyroptosis through the PI3K/AKT pathway.
Electroacupuncture Serum Alleviates Ogd/R-Induced Astrocyte Damage by Regulating the AQP4 Via m6A Methylation of lncRNA MALAT1.
The development and potent antitumor efficacy of CD44/CD133 dual-targeting IL7Rα-armored CAR-T cells against glioblastoma.
UCH-L1 Inhibitor Alleviates Nerve Damage Caused by Moyamoya Disease.
Perioperative enriched environment attenuates postoperative cognitive dysfunction by upregulating microglia TREM2 via PI3K/Akt pathway in mouse model of ischemic stroke.
Propofol and Dexmedetomidine Ameliorate Endotoxemia-Associated Encephalopathy via Inhibiting Ferroptosis.
Epileptic seizures induced by pentylenetetrazole kindling accelerate Alzheimer-like neuropathology in 5×FAD mice.
Salidroside ameliorates cerebral ischemic injury and regulates the glutamate metabolism pathway in astrocytes.
Microglial adenosine A(2A) receptor in the paraventricular thalamic nucleus regulates pain sensation and analgesic effects independent of opioid and cannabinoid receptors.
Astrocyte-derived exosomal miR-378a-5p mitigates cerebral ischemic neuroinflammation by modulating NLRP3-mediated pyroptosis.
Exploring the multifaceted therapeutic mechanism of Schisanlactone E (XTS) in APP/PS1 mouse model of Alzheimer's disease through multi-omics analysis.
Effect of Dl-3-n-Butylphthalide on olfaction in rotenone-induced Parkinson's rats.
Vagal innervation limits brain injury by inhibiting gut-selective integrin-mediated intestinal immunocyte migration in intracerebral hemorrhage.
MCT1-mediated endothelial cell lactate shuttle as a target for promoting axon regeneration after spinal cord injury.
Exosomes Derived from Meningitic Escherichia coli-Infected Brain Microvascular Endothelial Cells Facilitate Astrocyte Activation.
Endothelial lincRNA-p21 alleviates cerebral ischemia/reperfusion injury by maintaining blood-brain barrier integrity.
Distinct biological characteristics of mesenchymal stem cells separated from different components of human placenta.
Irisflorentin improves functional recovery after spinal cord injury by protecting the blood-spinal cord barrier and promoting axonal growth.
Restoration of defective oxidative phosphorylation to a subset of neurons prevents mitochondrial encephalopathy.
The RhoB p.S73F mutation leads to cerebral palsy through dysregulation of lipid homeostasis.
Withaferin A protects against epilepsy by promoting LCN2-mediated astrocyte polarization to stopping neuronal ferroptosis.
Acetate enables metabolic fitness and cognitive performance during sleep disruption.
SOLID: minimizing tissue distortion for brain-wide profiling of diverse architectures.
Investigation of Persistent Photoconductivity of Gallium Nitride Semiconductor and Differentiation of Primary Neural Stem Cells.
Ginsenoside compound K alleviates D-galactose-induced mild cognitive impairment by modulating gut microbiota-mediated short-chain fatty acid metabolism.
Cell-Type-Specific Expression of Leptin Receptors in the Mouse Forebrain.
Differential toxic and antiepileptic features of Vigabatrin raceme and its enantiomers.
Stereotactically intracerebral transplantation of neural stem cells for ischemic stroke attenuated inflammatory responses and promoted neurogenesis: an experimental study with monkeys.
Ferroptosis contributes to diabetes-induced visual pathway neuronal damage via iron accumulation and GPX4 inactivation.
Curcumin attenuated neuroinflammation via the TLR4/MyD88/NF-κB signaling way in the juvenile rat hippocampus following kainic acid-induced epileptic seizures.
Anti-CRMP2 antibody induces anxiety-like behavior and increases pyramidal neuron excitability in mice.
Role of mitochondrial dysfunction and biogenesis in fibromyalgia syndrome: Molecular mechanism in central nervous system.
The effects of BMP2 and the mechanisms involved in the invasion and angiogenesis of IDH1 mutant glioma cells.
Novel in vivo TDP-43 stress reporter models to accelerate drug development in ALS.
Mechanically adaptive and deployable intracortical probes enable long-term neural electrophysiological recordings.
Clinical characteristics of double negative atypical inflammatory demyelinating disease: A prospective study.
CX3CR1(+)/UCHL1(+) microglial extracellular vesicles in blood: a potential biomarker for multiple sclerosis.
Ferroptosis Regulated by 5-HT3a Receptor via Calcium/Calmodulin Signaling Contributes to Neuropathic Pain in Brachial Plexus Avulsion Rat Models.
Extracellular vesicles from neural stem cells safeguard neurons in intracerebral hemorrhage by suppressing reactive astrocyte neurotoxicity.
Targeting exosomal double-stranded RNA-TLR3 signaling pathway attenuates morphine tolerance and hyperalgesia.
TBC1D15-regulated mitochondria-lysosome membrane contact exerts neuroprotective effects by alleviating mitochondrial calcium overload in seizure.
CD2AP promotes the progression of glioblastoma multiforme via TRIM5-mediated NF-kB signaling.
Dysfunctional astrocyte glutamate uptake in the hypothalamic paraventricular nucleus contributes to visceral pain and anxiety-like behavior in mice with chronic pancreatitis.
S-(N,N-diethyldithiocarbamoyl)-N-acetyl-l-cysteine for the treatment of non-small cell lung cancer through regulating NF-κB signalling pathway without neurotoxicity.
The Neuroprotective Mechanisms of PPAR-γ: Inhibition of Microglia-Mediated Neuroinflammation and Oxidative Stress in a Neonatal Mouse Model of Hypoxic-Ischemic White Matter Injury.
Neonatal hypoxia-ischemia alters the events governing the hippocampal critical period of postnatal synaptic plasticity leading to deficits in working memory in mice.
Panobinostat Attenuates Experimental Autoimmune Encephalomyelitis in Mice via Suppressing Oxidative Stress-Related Neuroinflammation and Mitochondrial Dysfunction.
Reactive astrocytes promote tumor progression by up-regulating tumor protocadherin 1 expression in lung cancer brain metastasis.
Neutrophil-Mimetic Upconversion Photosynthetic Nanosystem Derived from Microalgae for Targeted Treatment of Thromboembolic Stroke.
Probiotics alleviate chronic ethanol exposure-induced anxiety-like behavior and hippocampal neuroinflammation in male mice through gut microbiota-derived extracellular vesicles.
DHA and EPA alleviate depressive-like behaviors in chronic sleep-deprived mice: Involvement of iron metabolism, oligodendrocyte-lipids peroxidation and the LCN2-NLRP3 signaling axis.
Dexmedetomidine Attenuates Neuroinflammation-Mediated Hippocampal Neurogenesis Impairment in Sepsis-Associated Encephalopathy Mice through Central α2A-Adrenoceptor.
The P38MAPK Pathway Mediates the Destruction of the Blood-Brain Barrier in Anti-NMDAR Encephalitis Mice.
Lentivirus-mediated Knockdown of Ski Improves Neurological Function After Spinal Cord Injury in Rats.
Abnormal hippocampal neurogenesis and impaired social recognition memory in two neurodevelopmental models of schizophrenia.
Jiawei Bai-Hu-decoction ameliorated heat stroke-induced brain injury by inhibiting TLR4/NF-κB signal and mitophagy of glial cell.
Exercise rescues cognitive impairment through inhibiting the fibrinogen neuroinflammative pathway in diabetes.
Exploring miR-21 as a key regulator in two distinct approaches of bone marrow stromal cells differentiation into Schwann-like cells.
Construction of functional neural network tissue combining CBD-NT3-modified linear-ordered collagen scaffold and TrkC-modified iPSC-derived neural stem cells for spinal cord injury repair.
Inhibition of ADORA3 promotes microglial phagocytosis and alleviates chronic ischemic white matter injury.
Glucose-modified BSA/procyanidin C1 NPs penetrate the blood-brain barrier and alleviate neuroinflammation in Alzheimer's disease models.
MG53/GMs/HA-Dex neural scaffold promotes the functional recovery of spinal cord injury by alleviating neuroinflammation.
Conditioned medium from human dental pulp stem cells treats spinal cord injury by inhibiting microglial pyroptosis.
Cerebral furin deficiency causes hydrocephalus in mice.
The Traf2 and NcK interacting kinase inhibitor NCB-0846 suppresses seizure activity involving the decrease of GRIA1.
Effect of Myelin Debris on the Phenotypic Transformation of Astrocytes after Spinal Cord Injury in Rats.
Pin1 Downregulation Is Involved in Excess Retinoic Acid-Induced Failure of Neural Tube Closure.
Effect of total flavonoids of Dracocephalum moldavica L. On neuroinflammation in Alzheimer's disease model amyloid-β (Aβ1-42)-peptide-induced astrocyte activation.
A robust vessel-labeling pipeline with high tissue clearing compatibility for 3D mapping of vascular networks.
Inhibition of sugar-binding activity of Galectins-8 by thiogalactoside (TDG) attenuates secondary brain damage and improves long-term prognosis following intracerebral hemorrhage.
Melatonin MT1 receptors regulate the Sirt1/Nrf2/Ho-1/Gpx4 pathway to prevent α-synuclein-induced ferroptosis in Parkinson's disease.
A New Approach for Exploring Reperfusion Brain Damage in Hypoxic Ischemic Encephalopathy.
Inhibiting the NLRP3 Inflammasome with MCC950 Alleviates Neurological Impairment in the Brain of EAE Mice.
Dl-3-n-Butylphthalide Alleviates Secondary Brain Damage and Improves Working Memory After Stroke in Cynomolgus Monkeys.
Rasd1 is involved in white matter injury through neuron-oligodendrocyte communication after subarachnoid hemorrhage.
Baicalein ameliorates cognitive impairment of vascular dementia rats via suppressing neuroinflammation and regulating intestinal microbiota.
Oxidative stress and mitochondrial dysfunction in brain of vinclozolin exposed animals.
Panax notoginseng saponins stimulates the differentiation and neurite development of C17.2 neural stem cells against OGD/R injuries via mTOR signaling.
Hypoxia inducible factor-1α regulates microglial innate immune memory and the pathology of Parkinson's disease.
Activation of astrocytes by ANXA2-derived extracellular vesicles from lung cancer cells affects aggressiveness, immunotherapy response and microenvironment of lung cancer.
A novel microglia-targeting strategy based on nanoparticle-mediated delivery of miR-26a-5p for long-lasting analgesia in chronic pain.
Gastrodia elata polysaccharide alleviates Parkinson's disease via inhibiting apoptotic and inflammatory signaling pathways and modulating the gut microbiota.
Human-induced pluripotent stem cell-derived neural stem/progenitor cell ex vivo gene therapy with synaptic organizer CPTX for spinal cord injury.
Repeated antibiotic drug treatment negatively affects memory function and glutamatergic nervous system of the hippocampus in mice.
Rab11 regulates autophagy at dendritic spines in an mTOR- and NMDA-dependent manner.
Periplaneta Americana (L.) extract activates the ERK/CREB/BDNF pathway to promote post-stroke neuroregeneration and recovery of neurological functions in rats.
Neuronal small extracellular vesicles carrying miR-181c-5p contribute to the pathogenesis of epilepsy by regulating the protein kinase C-δ/glutamate transporter-1 axis in astrocytes.
Injectable ultrasonic sensor for wireless monitoring of intracranial signals.
PHPB ameliorates memory deficits and reduces oxidative injury in Alzheimer's disease mouse model by activating Nrf2 signaling pathway.
Hippocampal mitophagy contributes to spatial memory via maintaining neurogenesis during the development of mice.
White matter hyperintensities and the surrounding normal appearing white matter are associated with water channel disruption in the oldest old.
Citrobacter rodentium infection impairs dopamine metabolism and exacerbates the pathology of Parkinson's disease in mice.
Pongamol Alleviates Neuroinflammation and Promotes Autophagy in Alzheimer's Disease by Regulating the Akt/mTOR Signaling Pathway.
Baricitinib ameliorates inflammatory and neuropathic pain in collagen antibody-induced arthritis mice by modulating the IL-6/JAK/STAT3 pathway and CSF-1 expression in dorsal root ganglion neurons.
Ginsenoside Rd enhances blood-brain barrier integrity after cerebral ischemia/reperfusion by alleviating endothelial cells ferroptosis via activation of NRG1/ErbB4-mediated PI3K/Akt/mTOR signaling pathway.
Codonopsis pilosula water extract delays D-galactose-induced aging of the brain in mice by activating autophagy and regulating metabolism.
A probe for NIR-II imaging and multimodal analysis of early Alzheimer's disease by targeting CTGF.
Psychobiotics Lactiplantibacillus plantarum JYLP-326: Antidepressant-like effects on CUMS-induced depressed mouse model and alleviation of gut microbiota dysbiosis.
The oxytocin receptor is essential for the protective effect of pair housing on post-stroke depression in mice.
P2Y6 Receptor Activation Aggravates NLRP3-dependent Microglial Pyroptosis via Downregulation of the PI3K/AKT Pathway in a Mouse Model of Intracerebral Hemorrhage.
A disulfiram derivative against lung cancer via the Notch signaling pathway without neurotoxicity and hepatotoxicity.
NDC80/HEC1 promotes macrophage polarization and predicts glioma prognosis via single-cell RNA-seq and in vitro experiment.
Targeting Phactr4 to rescue chronic stress-induced depression-like behavior in rats via regulating neuroinflammation and neuroplasticity.
Astaxanthin alleviates fibromyalgia pain and depression via NLRP3 inflammasome inhibition.
Zein-Based Triple-Drug Nanoparticles to Promote Anti-Inflammatory Responses for Nerve Regeneration after Spinal Cord Injury.
Brain Metastasis from EGFR-Mutated Non-Small Cell Lung Cancer: Secretion of IL11 from Astrocytes Up-Regulates PDL1 and Promotes Immune Escape.
Acid Neutralization by Composite Lysine Nanoparticles for Spinal Cord Injury Recovery through Mitigating Mitochondrial Dysfunction.
Lactylation of histone by BRD4 regulates astrocyte polarization after experimental subarachnoid hemorrhage.
Local Delivery of Dual Stem Cell-Derived Exosomes Using an Electrospun Nanofibrous Platform for the Treatment of Traumatic Brain Injury.
Intestinal microbiota imbalance resulted by anti-Toxoplasma gondii immune responses aggravate gut and brain injury.
Selenoprotein W modulates tau homeostasis in an Alzheimer's disease mouse model.
Multienzyme Active Nanozyme for Efficient Sepsis Therapy through Modulating Immune and Inflammation Inhibition.
TRAF6 promotes spinal microglial M1 polarization to aggravate neuropathic pain by activating the c-JUN/NF-kB signaling pathway.
Hypersensitivity of the vimentin cytoskeleton to net-charge states and Coulomb repulsion.
Disorder of neuroplasticity aggravates cognitive impairment via neuroinflammation associated with intestinal flora dysbiosis in chronic heart failure.
Mitochondria-targeted cerium vanadate nanozyme suppressed hypoxia-ischemia injury in neonatal mice via intranasal administration.
Melatonin exerts neuroprotective effects in mice with spinal cord injury by activating the Nrf2/Keap1 signaling pathway via the MT2 receptor.
BAFF deficiency aggravated optic nerve crush-induced retinal ganglion cells damage by regulating apoptosis and neuroinflammation via NF-κB-IκBα signaling.
Based on spinal central sensitization creating analgesic screening approach to excavate anti-neuropathic pain ingredients of Corydalis yanhusuo W.T.Wang.
MiR-31-5p regulates the neuroinflammatory response via TRAF6 in neuropathic pain.
hBcl2 overexpression in BMSCs enhances resistance to myelin debris-induced apoptosis and facilitates neuroprotection after spinal cord injury in rats.
BAF45D-binding to HOX genes was differentially targeted in H9-derived spinal cord neural stem cells.
Network pharmacology analysis of the active ingredients of Corydalis hendersonii Hemsl. and their effects on eliminating neuroinflammation and improving motor functions in MPTP-intoxicated mice.
Illustrate the distribution and metabolic regulatory effects of pterostilbene in cerebral ischemia-reperfusion rat brain by mass spectrometry imaging and spatial metabolomics.
TGN-020 Alleviate Inflammation and Apoptosis After Cerebral Ischemia-Reperfusion Injury in Mice Through Glymphatic and ERK1/2 Signaling Pathway.
Caffeic acid alleviates cerebral ischemic injury in rats by resisting ferroptosis via Nrf2 signaling pathway.
Erythrocyte membrane-coated nanocarriers modified by TGN for Alzheimer's disease.
Targeted transplantation of engineered mitochondrial compound promotes functional recovery after spinal cord injury by enhancing macrophage phagocytosis.
Sustainable inflammatory activation following spinal cord injury is driven by thrombin-mediated dynamic expression of astrocytic chemokines.
Inhibition of spinal Rac1 attenuates chronic inflammatory pain by regulating the activation of astrocytes.
Chronic Spinal Cord Injury Regeneration with Combined Therapy Comprising Neural Stem/Progenitor Cell Transplantation, Rehabilitation, and Semaphorin 3A Inhibitor.
Sulbactam protects neurons against double neurotoxicity of amyloid beta and glutamate load by upregulating glial glutamate transporter 1.
Bicarbonate signalling via G protein-coupled receptor regulates ischaemia-reperfusion injury.
A Comparative Biochemical and Pathological Evaluation of Brain Samples from Knock-In Murine Models of Gaucher Disease.
Potential Role of Bmal1 in Lipopolysaccharide-Induced Depression-Like Behavior and its Associated "Inflammatory Storm".
Disease-Associated Neurotoxic Astrocyte Markers in Alzheimer Disease Based on Integrative Single-Nucleus RNA Sequencing.
Regulation of TAR DNA binding protein 43 (TDP-43) homeostasis by cytosolic DNA accumulation.
Identification of Brain Cell Type-Specific Therapeutic Targets for Glioma From Genetics.
Interleukin-3 Modulates Macrophage Phagocytic Activity and Promotes Spinal Cord Injury Repair.
Activation of the Nrf2/Keap1 signaling pathway mediates the neuroprotective effect of Perillyl alcohol against cerebral hypoxic-ischemic damage in neonatal rats.
Gut microbiota modification by diosgenin mediates antiepileptic effects in a mouse model of epilepsy.
Ginsenoside compound K alleviates brain aging by inhibiting ferroptosis through modulation of the ASK1-MKK7-JNK signaling pathway.
AD-Like Neuropsychiatric Dysfunction in a Mice Model Induced by a Combination of High-Fat Diet and Intraperitoneal Injection of Streptozotocin.
Neuron-like lineage differentiation induced by exogenous Neurexin-1 as a potential therapeutic strategy for glioma.
Liu-Shen-Wan inhibits PI3K/Akt and TRPV1 signaling alleviating bone cancer pain in rats.
Histological effects of combined therapy involving scar resection, decellularized scaffolds, and human iPSC-NS/PCs transplantation in chronic complete spinal cord injury.
Neuroprotective effects of gypenosides on LPS-induced anxiety and depression-like behaviors.
Evaluation of the Neuroprotective Effect of Total Glycosides of Cistanche deserticola and Investigation of Novel Brain-Targeting Natural MAO-B Inhibitors.
Exploring PDE5A upregulation in bipolar disorder: insights from single-nucleus RNA sequencing of human basal ganglia.
The crucial role of NR2A mediating the activation of satellite glial cells in the trigeminal ganglion contributes to orofacial inflammatory pain during TMJ inflammation.
TRIM24-DTNBP1-ATP7A mediated astrocyte cuproptosis in cognition and memory dysfunction caused by Y(2)O(3) NPs.
Propofol Mitigates Sepsis-Induced Brain Injury by Inhibiting Ferroptosis Via Activation of the Nrf2/HO-1axis.
Targeted inhibition of autophagy in hepatic stellate cells by hydroxychloroquine: An effective therapeutic approach for the treatment of liver fibrosis.
Silencing CXCL16 alleviate neuroinflammation and M1 microglial polarization in mouse brain hemorrhage model and BV2 cell model through PI3K/AKT pathway.
Protective effect of melatonin against metabolic disorders and neuropsychiatric injuries in type 2 diabetes mellitus mice.
Quercetin-loaded Human Umbilical cord Mesenchymal Stem Cell-derived sEVs for Spinal Cord Injury Recovery.
Emodin attenuates hypoxic-ischemic brain damage by inhibiting neuronal apoptosis in neonatal mice.
Tetramethylpyrazine alleviates ferroptosis and promotes functional recovery in spinal cord injury by regulating GPX4/ACSL4.
Fisetin Promotes Functional Recovery after Spinal Cord Injury by Inhibiting Microglia/Macrophage M1 Polarization and JAK2/STAT3 Signaling Pathway.
Du-moxibustion ameliorates depression-like behavior and neuroinflammation in chronic unpredictable mild stress-induced mice.
Toll-like receptor 3 signaling drives enteric glial cells against dextran sulfate sodium-induced colitis in mice.
MFG-E8 Alleviates Cognitive Impairments Induced by Chronic Cerebral Hypoperfusion by Phagocytosing Myelin Debris and Promoting Remyelination.
Spinal sirtuin 2 attenuates bone cancer pain by deacetylating FoxO3a.
DNMT3A promotes glioma growth and malignancy via TNF-α/NF-κB signaling pathway.
Distributional coding of associative learning in discrete populations of midbrain dopamine neurons.
Enriched Environment Inhibits Neurotoxic Reactive Astrocytes via JAK2-STAT3 to Promote Glutamatergic Synaptogenesis and Cognitive Improvement in Chronic Cerebral Hypoperfusion Rats.
Neuron-targeted liposomal coenzyme Q10 attenuates neuronal ferroptosis after subarachnoid hemorrhage by activating the ferroptosis suppressor protein 1/coenzyme Q10 system.
Selective disruption of mTORC1 and mTORC2 in VTA astrocytes induces depression and anxiety-like behaviors in mice.
KYNA Ameliorates Glutamate Toxicity of HAND by Enhancing Glutamate Uptake in A2 Astrocytes.
5-HT3a receptor contributes to neuropathic pain by regulating central sensitization in a rat with brachial plexus avulsion.
Defective neurite elongation and branching in Nibp/Trappc9 deficient zebrafish and mice.
Loss of RAB39B does not alter MPTP-induced Parkinson's disease-like phenotypes in mice.
Development of an ultrasensitive microfluidic assay for the analysis of Glial fibrillary acidic protein (GFAP) in blood.
Directed Neural Stem Cells Differentiation via Signal Communication with Ni-Zn Micromotors.
Isoflurane impairs olfaction by increasing neuronal activity in the olfactory bulb.
5-Hydroxytryptamine: a potential therapeutic target in amyotrophic lateral sclerosis.
Biliverdin modulates the Nrf2/A20/eEF1A2 axis to alleviate cerebral ischemia-reperfusion injury by inhibiting pyroptosis.
Neuron-derived extracellular vesicles contain synaptic proteins, promote spine formation, activate TrkB-mediated signalling and preserve neuronal complexity.
Xiangshao Decoction alleviates gastric mucosal injury through NRF2 signaling pathway and reduces neuroinflammation in gastric ulcer rats.
Glioma-derived small extracellular vesicles induce pericyte-phenotype transition of glioma stem cells under hypoxic conditions.
MDM2 upregulation induces mitophagy deficiency via Mic60 ubiquitination in fetal microglial inflammation and consequently neuronal DNA damage caused by exposure to ZnO-NPs during pregnancy.
Human umbilical cord-derived mesenchymal stem cells ameliorate perioperative neurocognitive disorder by inhibiting inflammatory responses and activating BDNF/TrkB/CREB signaling pathway in aged mice.
Transmembrane protein 184B (TMEM184B) promotes expression of synaptic gene networks in the mouse hippocampus.
Long-term potentiation-based screening identifies neuronal PYGM as a synaptic plasticity regulator participating in Alzheimer's disease.
Protocol for fine casting, imaging, and analysis of murine vascular networks with VALID.
A microtubule stabilizer ameliorates protein pathogenesis and neurodegeneration in mouse models of repetitive traumatic brain injury.
Long-term iTBS Improves Neural Functional Recovery by Reducing the Inflammatory Response and Inhibiting Neuronal Apoptosis Via miR-34c-5p/p53/Bax Signaling Pathway in Cerebral Ischemic Rats.
Alleviating symptoms of neurodegenerative disorders by astrocyte-specific overexpression of TMEM164 in mice.
Electroacupuncture ameliorates cardiac dysfunction in myocardial ischemia model rats: a potential role of the hypothalamic-pituitary-adrenal axis.
Determinants of astrocytic pathology in stem cell models of primary tauopathies.
Anti-inflammatory effects of myristic acid mediated by the NF-κB pathway in lipopolysaccharide-induced BV-2 microglial cells.
Neurovascular protection of alisol A on cerebral ischemia mice through activating the AKT/GSK3β pathway.
Enteric glial cells aggravate the intestinal epithelial barrier damage by secreting S100β under high-altitude conditions.
Hepatocyte growth factor pretreatment boosts functional recovery after spinal cord injury through human iPSC-derived neural stem/progenitor cell transplantation.
Enriched environment attenuates ferroptosis after cerebral ischemia/reperfusion injury by regulating iron metabolism.
Attenuation of Chronic Stress-Induced Depressive-like Symptoms by Fish Oil via Alleviating Neuroinflammation and Impaired Tryptophan Metabolism in Aging Rats.
Agomir-331 Suppresses Reactive Gliosis and Neuroinflammation after Traumatic Brain Injury.
Aluminum exposure induces central nervous system impairment via activating NLRP3-medicated pyroptosis pathway.
Umbilical cord mesenchymal stem cell-conditioned medium inhibits microglial activation to ameliorate neuroinflammation in amyotrophic lateral sclerosis mice and cell models.
NCBP1 Improves Cognitive Function in Mice by Reducing Oxidative Stress, Neuronal Loss, and Glial Activation After Status Epilepticus.
Catalpol Alleviates Ischemic Stroke Through Promoting Angiogenesis and Facilitating Proliferation and Differentiation of Neural Stem Cells via the VEGF-A/KDR Pathway.
Gut microbiome-derived ammonia modulates stress vulnerability in the host.
Inhibition of ANXA2 activity attenuates epileptic susceptibility and GluA1 phosphorylation.
Potential value of Interleukin-6 as a diagnostic biomarker in human MDD and the antidepressant effect of its receptor antagonist tocilizumab in lipopolysaccharide-challenged rats.
Deferoxamine attenuates visual impairment in retinal ischemia‒reperfusion via inhibiting ferroptosis.
TLR2 deficiency is beneficial at the late phase in MPTP-induced Parkinson' disease mice.
In vivo labeling and quantitative imaging of neuronal populations using MRI.
Dulaglutide Improves Gliosis and Suppresses Apoptosis/Autophagy Through the PI3K/Akt/mTOR Signaling Pathway in Vascular Dementia Rats.
IL1RAP Knockdown in LPS-Stimulated Normal Human Astrocytes Suppresses LPS-Induced Reactive Astrogliosis and Promotes Neuronal Cell Proliferation.
miR-26a-5p alleviates CFA-induced chronic inflammatory hyperalgesia through Wnt5a/CaMKII/NFAT signaling in mice.
Increased level of RAB39B leads to neuronal dysfunction and behavioural changes in mice.
Spinal astrocytic MeCP2 regulates Kir4.1 for the maintenance of chronic hyperalgesia in neuropathic pain.
Bone marrow mesenchymal stem cells and exercise restore motor function following spinal cord injury by activating PI3K/AKT/mTOR pathway.
Double-target neural circuit-magnetic stimulation improves motor function in spinal cord injury by attenuating astrocyte activation.
The BET PROTAC inhibitor dBET6 protects against retinal degeneration and inhibits the cGAS-STING in response to light damage.
Multi-omics analysis of a drug-induced model of bipolar disorder in zebrafish.
Mesenchymal stem cells transplantation combined with IronQ attenuates ICH-induced inflammation response via Mincle/syk signaling pathway.
Endothelial depletion of Atg7 triggers astrocyte-microvascular disassociation at blood-brain barrier.
HSPA1A ameliorated spinal cord injury in rats by inhibiting apoptosis to exert neuroprotective effects.
LAMP-2A ablation in hippocampal CA1 astrocytes confers cerebroprotection and ameliorates neuronal injury after global brain ischemia.
β2-Microglobulin exacerbates neuroinflammation, brain damage, and cognitive impairment after stroke in rats.
Deletion of Bak1 alleviates microglial necroptosis and neuroinflammation after experimental subarachnoid hemorrhage.
Isolation, culture, and characterization of duck primary neurons.
Kynurenic acid blunts A1 astrocyte activation against neurodegeneration in HIV-associated neurocognitive disorders.
Azithromycin and Sildenafil May Have Protective Effects on Retinal Ganglion Cells via Different Pathways: Study in a Rodent Microbead Model.
Swimming training combined with fecal microbial transplantation protects motor functions in rats with spinal cord injury by improving the intestinal system.
Activation of TLR7-mediated autophagy increases epileptic susceptibility via reduced KIF5A-dependent GABA(A) receptor transport in a murine model.
Blocking Two-Pore Domain Potassium Channel TREK-1 Inhibits the Activation of A1-Like Reactive Astrocyte Through the NF-κB Signaling Pathway in a Rat Model of Major Depressive Disorder.
Glial cell line-derived neurotrophic factor and brain-derived neurotrophic factor regulate the interaction between astrocytes and Schwann cells at the trigeminal root entry zone.
HDAC6 Deficiency Has Moderate Effects on Behaviors and Parkinson's Disease Pathology in Mice.
Tonic Meningeal Interleukin-10 Upregulates Delta Opioid Receptor to Prevent Relapse to Pain.
Limb Remote Ischemic Postconditioning Improves Glymphatic Dysfunction After Cerebral Ischemia-Reperfusion Injury.
Lymphocyte-Related Immunomodulatory Therapy with Siponimod (BAF-312) Improves Outcomes in Mice with Acute Intracerebral Hemorrhage.
Parthenolide alleviates microglia-mediated neuroinflammation via MAPK/TRIM31/NLRP3 signaling to ameliorate cognitive disorder.
Ketogenic diet attenuates neuroinflammation and induces conversion of M1 microglia to M2 in an EAE model of multiple sclerosis by regulating the NF-κB/NLRP3 pathway and inhibiting HDAC3 and P2X7R activation.
Ginsenoside-Rg1 synergized with voluntary running exercise protects against glial activation and dysregulation of neuronal plasticity in depression.
Schwann cells regulate tumor cells and cancer-associated fibroblasts in the pancreatic ductal adenocarcinoma microenvironment.
Modulation of the Proliferative Pathway, Neuroinflammation and Pain in Endometriosis.
Multi-omics analysis reveals BDE47 induces depression-like behaviors in mice by interfering with the 2-arachidonoyl glycerol-associated microbiota-gut-brain axis.
Repeated sevoflurane exposures inhibit neurogenesis by inducing the upregulation of glutamate transporter 1 in astrocytes.
Clptm1, a new target in suppressing epileptic seizure by regulating GABA(A) R-mediated inhibitory synaptic transmission in a PTZ-induced epilepsy model.
Fra-1 induces apoptosis and neuroinflammation by targeting S100A8 to modulate TLR4 pathways in spinal cord ischemia/reperfusion injury.
Ginsenoside Rg1 promotes astrocyte-to-neuron transdifferentiation in rat and its possible mechanism.
Tocilizumab promotes repair of spinal cord injury by facilitating the restoration of tight junctions between vascular endothelial cells.
Role of NF-κB in lead exposure-induced activation of astrocytes based on bioinformatics analysis of hippocampal proteomics.
Integration of genetically engineered virus nanofibers and fibrin to form injectable fibrous neuron-rich hydrogels and enable neural differentiation.
Platelet-Rich Plasma Gel-Loaded Collagen/Chitosan Composite Film Accelerated Rat Sciatic Nerve Injury Repair.
Superenhancer activation of KLHDC8A drives glioma ciliation and hedgehog signaling.
Thioflavin S Staining and Amyloid Formation Are Unique to Mixed Tauopathies.
The protective effect of inhibiting mitochondrial fission on the juvenile rat brain following PTZ kindling through inhibiting the BCL2L13/LC3 mitophagy pathway.
Human cytomegalovirus pUL97 upregulates SOCS3 expression via transcription factor RFX7 in neural progenitor cells.
Caffeic acid protects against atherosclerotic lesions and cognitive decline in ApoE(-/-) mice.
Honokiol alleviated neurodegeneration by reducing oxidative stress and improving mitochondrial function in mutant SOD1 cellular and mouse models of amyotrophic lateral sclerosis.
A versatile vessel casting method for fine mapping of vascular networks using a hydrogel-based lipophilic dye solution.
Peroxiredoxin-6 Released by Astrocytes Contributes to Neuroapoptosis During Ischemia.
A Simple 3D Cell Culture Method for Studying the Interactions between Human Mesenchymal Stromal/Stem Cells and Patients Derived Glioblastoma.
Circular RNA METTL9 contributes to neuroinflammation following traumatic brain injury by complexing with astrocytic SND1.
Enrofloxacin exposure induces anxiety-like behavioral responses in zebrafish by affecting the microbiota-gut-brain axis.
Bumetanide Rescues Aquaporin-4 Depolarization via Suppressing β-Dystroglycan Cleavage and Provides Neuroprotection in Rat Retinal Ischemia-Reperfusion Injury.
Neurotoxic A1 astrocytes promote neuronal ferroptosis via CXCL10/CXCR3 axis in epilepsy.
Mitochondrial fission drives neuronal metabolic burden to promote stress susceptibility in male mice.
Astrocytes and microglia-targeted Danshensu liposomes enhance the therapeutic effects on cerebral ischemia-reperfusion injury.
Effects of electroacupuncture on glial scar generation in SCI model rats.
Epstein-Barr virus: To be a trigger of autoimmune glial fibrillary acidic protein astrocytopathy?
Ischemic Preconditioning Alleviates Cerebral Ischemia-Reperfusion Injury by Interfering With Glycocalyx.
P-hydroxy benzaldehyde facilitates reprogramming of reactive astrocytes into neurons via endogenous transcriptional regulation.
Pregabalin inhibits purinergic P2Y(2) receptor and TRPV4 to suppress astrocyte activation and to relieve neuropathic pain.
Early-Stage Application of Agomir-137 Promotes Locomotor Recovery in a Mouse Model of Motor Cortex Injury.
Neuroinflammation-induced parvalbumin interneuron and oscillation deficits might contribute to neurobehavioral abnormities in a two-hit model of depression.
Sirt1 Overexpression Inhibits Fibrous Scar Formation and Improves Functional Recovery After Cerebral Ischemic Injury Through the Deacetylation of 14-3-3ζ.
Lycium barbarum glycopeptide targets PER2 to inhibit lipogenesis in glioblastoma by downregulating SREBP1c.
Synergistic effects of lipopolysaccharide and rotenone on dopamine neuronal damage in rats.
Berberine-loaded MSC-derived sEVs encapsulated in injectable GelMA hydrogel for spinal cord injury repair.
Bioactive NIR-II gold clusters for three-dimensional imaging and acute inflammation inhibition.
Exosomes secreted by mesenchymal stem cells delay brain aging by upregulating SIRT1 expression.
Evaluation of BDE-47-induced neurodevelopmental toxicity in zebrafish embryos.
Microenvironmental modulation in tandem with human stem cell transplantation enhances functional recovery after chronic complete spinal cord injury.
Lipid-accumulated reactive astrocytes promote disease progression in epilepsy.
Geranylgeranylacetone-induced heat shock protein70 expression reduces retinal ischemia-reperfusion injury through PI3K/AKT/mTOR signaling.
Engineered Extracellular Vesicle-Delivered CRISPR/CasRx as a Novel RNA Editing Tool.
Oral feeding of nanoplastics affects brain function of mice by inducing macrophage IL-1 signal in the intestine.
NOD-like receptor NLRC5 promotes neuroinflammation and inhibits neuronal survival in Parkinson's disease models.
Mitochondrial-targeting fluorescent small molecule IR-780 alleviates radiation-induced brain injury.
Cryo-Shocked Platelet Coupled with ROS-Responsive Nanomedicine for Targeted Treatment of Thromboembolic Disease.
The role of reactive astrocytes in neurotoxicity induced by ultrafine particulate matter.
Functional OCT angiography reveals early retinal neurovascular dysfunction in diabetes with capillary resolution.
Icariside II Attenuates Methamphetamine-Induced Neurotoxicity and Behavioral Impairments via Activating the Keap1-Nrf2 Pathway.
The Dectin-1 Receptor Signaling Pathway Mediates the Remyelination Effect of Lentinan through Suppression of Neuroinflammation and Conversion of Microglia.
Diet-Induced High Serum Levels of Trimethylamine-N-oxide Enhance the Cellular Inflammatory Response without Exacerbating Acute Intracerebral Hemorrhage Injury in Mice.
Decitabine attenuates ischemic stroke by reducing astrocytes proliferation in rats.
Conditional deletion of MAD2B in forebrain neurons enhances hippocampus-dependent learning and memory in mice.
Periodontitis Salivary Microbiota Aggravates Ischemic Stroke Through IL-17A.
Rare KCND3 Loss-of-Function Mutation Associated With the SCA19/22.
NF-κB and AP-1 are required for the lipopolysaccharide-induced expression of MCP-1, CXCL1, and Cx43 in cultured rat dorsal spinal cord astrocytes.
Blood-nerve barrier disruption and coagulation system activation induced by mechanical compression injury participate in the peripheral sensitization of trigeminal neuralgia.
Molar loss further exacerbates 2-VO-induced cognitive impairment associated with the activation of p38MAPK/NFκB pathway.
Effect of β-hydroxybutyrate on behavioral alterations, molecular and morphological changes in CNS of multiple sclerosis mouse model.
TAZ Induces Migration of Microglia and Promotes Neurological Recovery After Spinal Cord Injury.
Coeloglossum viride Var. Bracteatum Extract Attenuates MPTP-Induced Neurotoxicity in vivo by Restoring BDNF-TrkB and FGF2-Akt Signaling Axis and Inhibiting RIP1-Driven Inflammation.
DAPT Attenuates Cadmium-Induced Toxicity in Mice by Inhibiting Inflammation and the Notch/HES-1 Signaling Axis.
Edaravone Dexborneol Treatment Attenuates Neuronal Apoptosis and Improves Neurological Function by Suppressing 4-HNE-Associated Oxidative Stress After Subarachnoid Hemorrhage.
Alpha-Asaronol Alleviates Dysmyelination by Enhancing Glutamate Transport Through the Activation of PPARγ-GLT-1 Signaling in Hypoxia-Ischemia Neonatal Rats.
Dual Effects: Intrastriatal Injection of α-syn N103/tau N368 Preformed Fibrils Promotes Endogenous α-synuclein Aggregates in the Proximal Colon.
Continuous theta-burst stimulation enhances and sustains neurogenesis following ischemic stroke.
Vagus nerve stimulation promotes the M1-to-M2 transition via inhibition of TLR4/NF-κB in microglial to rescue the reperfusion injury.
Temporal and Sex-Linked Protein Expression Dynamics in a Familial Model of Alzheimer's Disease.
Bilateral intracerebroventricular injection of streptozotocin induces AD-like behavioral impairments and neuropathological features in mice: Involved with the fundamental role of neuroinflammation.
Human PMSCs-derived small extracellular vesicles alleviate neuropathic pain through miR-26a-5p/Wnt5a in SNI mice model.
Delivery of miRNAs through Metal-Organic Framework Nanoparticles for Assisting Neural Stem Cell Therapy for Ischemic Stroke.
Imatinib inhibits pericyte-fibroblast transition and inflammation and promotes axon regeneration by blocking the PDGF-BB/PDGFRβ pathway in spinal cord injury.
Apelin-13 reduces lipopolysaccharide-induced neuroinflammation and cognitive impairment via promoting glucocorticoid receptor expression and nuclear translocation.
A Mouse Model of Neurodegeneration Induced by Blade Penetrating Stab Wound to the Hippocampus.
Pedigree-based study to identify GOLGB1 as a risk gene for bipolar disorder.
Flufenamic acid improves survival and neurologic outcome after successful cardiopulmonary resuscitation in mice.
Rac-deficient cerebellar granule neurons die before they migrate to the internal granule layer.
Effects of intraperitoneal injection of lipopolysaccharide-induced peripheral inflammation on dopamine neuron damage in rat midbrain.
Celastrol inhibits pathologic neovascularization in oxygen-induced retinopathy by targeting the miR-17-5p/HIF-1α/VEGF pathway.
Apelin-13 attenuates depressive-like behaviors induced by chronic unpredictable mild stress via activating AMPK/PGC-1α/FNDC5/BDNF pathway.
Neuroprotective Effect of Azithromycin Following Induction of Optic Nerve Crush in Wild Type and Immunodeficient Mice.
Treadmill Exercise Modulates Intestinal Microbes and Suppresses LPS Displacement to Alleviate Neuroinflammation in the Brains of APP/PS1 Mice.
LY6E protein facilitates adeno-associated virus crossing in a biomimetic chip model of the human blood-brain barrier.
Oncofetal protein IGF2BP1 regulates IQGAP3 expression to maintain stem cell potential in cancer.
S100A8 regulates autophagy-dependent ferroptosis in microglia after experimental subarachnoid hemorrhage.
Differential roles of NMDAR subunits 2A and 2B in mediating peripheral and central sensitization contributing to orofacial neuropathic pain.
Functions of retinal astrocytes and Müller cells in mammalian myopia.
Spinal cord astrocytes regulate myocardial ischemia-reperfusion injury.
Decreased Spire2 Expression is Involved in Epilepsy.
Administration of C5a Receptor Antagonist Improves the Efficacy of Human Induced Pluripotent Stem Cell-Derived Neural Stem/Progenitor Cell Transplantation in the Acute Phase of Spinal Cord Injury.
sEVs(RVG) selectively delivers antiviral siRNA to fetus brain, inhibits ZIKV infection and mitigates ZIKV-induced microcephaly in mouse model.
Adeno-associated virus-mediated in vivo suppression of expression of EPHX2 gene modulates the activity of paraventricular nucleus neurons in spontaneously hypertensive rats.
Inhibition of ROCK2 kinase activity improved behavioral deficits and reduced neuron damage in a DEACMP rat model.
Involvement of the BDNF-TrkB-KCC2 pathway in neuropathic pain after brachial plexus avulsion.
Gut microbiota shapes social dominance through modulating HDAC2 in the medial prefrontal cortex.
Salidroside alleviates cadmium-induced toxicity in mice by restoring the notch/HES-1 and RIP1-driven inflammatory signaling axis.
Mechanistic Insights into Ameliorating Effect of Geraniol on D-Galactose Induced Memory Impairment in Rats.
Effects of ketogenic diet on cognitive functions of mice fed high-fat-high-cholesterol diet.
Pancreatic Stellate Cells Prolong Ex Vivo Islet Viability and Function and Improve Engraftment.
Attenuation of histone H4 lysine 16 acetylation (H4K16ac) elicits a neuroprotection against ischemic stroke by alleviating the autophagic/lysosomal dysfunction in neurons at the penumbra.
Anti-IgLON5 antibodies cause progressive behavioral and neuropathological changes in mice.
Astragalin attenuates AlCl(3)/D-galactose-induced aging-like disorders by inhibiting oxidative stress and neuroinflammation.
MG53 protein rejuvenates hUC-MSCs and facilitates their therapeutic effects in AD mice by activating Nrf2 signaling pathway.
N-Acetylcysteine alleviates spinal cord injury in rats after early decompression surgery by regulating inflammation and apoptosis.
Neuroprotective effects of CysLTR antagonist on Streptococcus pneumoniae-induced meningitis in rats.
Pulsed-Focused Ultrasound Provides Long-Term Suppression of Epileptiform Bursts in the Kainic Acid-Induced Epilepsy Rat Model.
UPF1/circRPPH1/ATF3 feedback loop promotes the malignant phenotype and stemness of GSCs.
Ror2 mediates chronic post-thoracotomy pain by inducing the transformation of A1/A2 reactive astrocytes in rats.
The role of regulatory T cells on the activation of astrocytes in the brain of high-fat diet mice following lead exposure.
Malignant Melanoma-Derived Exosomes Induce Endothelial Damage and Glial Activation on a Human BBB Chip Model.
The adaptor SH2B1 and the phosphatase PTP4A1 regulate the phosphorylation of cytohesin-2 in myelinating Schwann cells in mice.
A congenital CMV infection model for follow-up studies of neurodevelopmental disorders, neuroimaging abnormalities, and treatment.
Folic Acid Inhibits Aging-Induced Telomere Attrition and Apoptosis in Astrocytes In Vivo and In Vitro.
Coeloglossum viride var. bracteatum extract attenuates Aβ-induced toxicity by inhibiting RIP1-driven inflammation and necroptosis.
Neuroprotective effects of liraglutide against inflammation through the AMPK/NF-κB pathway in a mouse model of Parkinson's disease.
The histone deacetylase inhibitor belinostat ameliorates experimental autoimmune encephalomyelitis in mice by inhibiting TLR2/MyD88 and HDAC3/ NF-κB p65-mediated neuroinflammation.
The N-Terminal Region of Middle East Respiratory Syndrome Coronavirus Accessory Protein 8b Is Essential for Enhanced Virulence of an Attenuated Murine Coronavirus.
Neuroprotective effects of alisol A 24-acetate on cerebral ischaemia-reperfusion injury are mediated by regulating the PI3K/AKT pathway.
Exosomes derived from bone-marrow mesenchymal stem cells alleviate cognitive decline in AD-like mice by improving BDNF-related neuropathology.
Silk fibroin nanofibrous scaffolds incorporated with microRNA-222 loaded chitosan nanoparticles for enhanced neuronal differentiation of neural stem cells.
Maternal sevoflurane exposure affects neural stem cell differentiation in offspring rats through NRF2 signaling.
Histological and molecular characterization of glaucoma model induced by one or two injections of microbeads to the anterior chamber of mice.
Early Diagnosis of Murine Sepsis-Associated Encephalopathy Using Dynamic PET/CT Imaging and Multiparametric MRI.
Astrocyte-derived sEVs alleviate fibrosis and promote functional recovery after spinal cord injury in rats.
Dysregulation of ErbB4 Signaling Pathway in the Dorsal Hippocampus after Neonatal Hypoxia-Ischemia and Late Deficits in PV(+) Interneurons, Synaptic Plasticity and Working Memory.
Postmortem 7T MRI for guided histopathology and evaluation of cerebrovascular disease.
Melatonin attenuates bone cancer pain via the SIRT1/HMGB1 pathway.
RSL3 triggers glioma stem cell differentiation via the Tgm2/AKT/ID1 signaling axis.
Gold Nanostrip Array-Mediated Wireless Electrical Stimulation for Accelerating Functional Neuronal Differentiation.
EMMPRIN Promotes the Expression of MMP-9 and Exacerbates Neurological Dysfunction in a Mouse Model of Intracerebral Hemorrhage.
Taurine supplementation improves hippocampal metabolism in immature rats with intrauterine growth restriction (IUGR) through protecting neurons and reducing gliosis.
Preventive effects of arctigenin from Arctium lappa L against LPS-induced neuroinflammation and cognitive impairments in mice.
Focused ultrasound/microbubbles-assisted BBB opening enhances LNP-mediated mRNA delivery to brain.
Construction and identification of an immortalized rat intestinal smooth muscle cell line.
The contribution of proteasomal impairment to autophagy activation by C9orf72 poly-GA aggregates.
Gene delivery of chitosan-graft-polyethyleneimine vectors loaded on scaffolds for nerve regeneration.
A non-invasive system to monitor in vivo neural graft activity after spinal cord injury.
Maresin 1 improves cognitive decline and ameliorates inflammation and blood-brain barrier damage in rats with chronic cerebral hypoperfusion.
Maternal stress programs a demasculinization of glutamatergic transmission in stress-related brain regions of aged rats.
Stemness Maintenance and Massproduction of Neural Stem Cells on Poly L-Lactic Acid Nanofibrous Membrane Based on Piezoelectriceffect.
Cannabidiol prevents depressive-like behaviors through the modulation of neural stem cell differentiation.
NLRP3 inflammasome of microglia promotes A1 astrocyte transformation, neo-neuron decline and cognition impairment in endotoxemia.
Intranasal Administration of Agomir-let-7i Improves Cognitive Function in Mice with Traumatic Brain Injury.
Profiling of Sexually Dimorphic Genes in Neural Cells to Identify Eif2s3y, Whose Overexpression Causes Autism-Like Behaviors in Male Mice.
Oridonin Alleviates LPS-Induced Depression by Inhibiting NLRP3 Inflammasome via Activation of Autophagy.
Gut Microbiota Disorders Promote Inflammation and Aggravate Spinal Cord Injury Through the TLR4/MyD88 Signaling Pathway.
Neuroprotective Effect of Ceftriaxone on MPTP-Induced Parkinson's Disease Mouse Model by Regulating Inflammation and Intestinal Microbiota.
Combined Use of Chitosan and Olfactory Mucosa Mesenchymal Stem/Stromal Cells to Promote Peripheral Nerve Regeneration In Vivo.
The Role of Exercise in Reducing Hyperlipidemia-Induced Neuronal Damage in Apolipoprotein E-Deficient Mice.
Dl-3-n-Butylphthalide Reduces Cognitive Deficits and Alleviates Neuropathology in P301S Tau Transgenic Mice.
Alteration of N (6) -Methyladenosine mRNA Methylation in a Rat Model of Cerebral Ischemia-Reperfusion Injury.
Dl-3-n-Butylphthalide Rescues Dopaminergic Neurons in Parkinson's Disease Models by Inhibiting the NLRP3 Inflammasome and Ameliorating Mitochondrial Impairment.
Fascin-1 is Highly Expressed Specifically in Microglia After Spinal Cord Injury and Regulates Microglial Migration.
Resveratrol Alleviates Levodopa-Induced Dyskinesia in Rats.
Catalytic patch with redox Cr/CeO(2) nanozyme of noninvasive intervention for brain trauma.
Edaravone attenuates cadmium-induced toxicity by inhibiting oxidative stress and inflammation in ICR mice.
The Long Non-coding RNA NEAT1/miR-224-5p/IL-33 Axis Modulates Macrophage M2a Polarization and A1 Astrocyte Activation.
Lack of Mof reduces acute liver injury by enhancing transcriptional activation of Igf1.
Utilizing the Faxitron MultiRad 225 X-ray irradiation system for the construction of mouse chronic whole brain radiation model.
Overexpression of miR-338-5p in exosomes derived from mesenchymal stromal cells provides neuroprotective effects by the Cnr1/Rap1/Akt pathway after spinal cord injury in rats.
Ketamine ameliorates depressive-like behaviors in mice through increasing glucose uptake regulated by the ERK/GLUT3 signaling pathway.
Sleep disturbance induces depressive behaviors and neuroinflammation by altering the circadian oscillations of clock genes in rats.
Inhibition of sEH via stabilizing the level of EETs alleviated Alzheimer's disease through GSK3β signaling pathway.
Astrocytic Kir4.1 regulates NMDAR/calpain signaling axis in lipopolysaccharide-induced depression-like behaviors in mice.
Aluminum impairs cognitive function by activating DDX3X-NLRP3-mediated pyroptosis signaling pathway.
Vagus nerve stimulation mediates microglia M1/2 polarization via inhibition of TLR4 pathway after ischemic stroke.
Deficiency of cGAS signaling protects against sepsis-associated encephalopathy.
The seed oil of Paeonia ludlowii ameliorates Aβ25-35-induced Alzheimer's disease in rats.
Proteomic analysis of aged and OPTN E50K retina in the development of normal tension glaucoma.
A diet high in sugar and fat influences neurotransmitter metabolism and then affects brain function by altering the gut microbiota.
Activation of FXR by ganoderic acid A promotes remyelination in multiple sclerosis via anti-inflammation and regeneration mechanism.
A five-m6A regulatory gene signature is a prognostic biomarker in lung adenocarcinoma patients.
Modulation of the HMGB1/TLR4/NF-κB signaling pathway in the CNS by matrine in experimental autoimmune encephalomyelitis.
Taurine improves the differentiation of neural stem cells in fetal rats with intrauterine growth restriction via activation of the PKA-CREB-BDNF signaling pathway.
Ganoderma lucidum polysaccharides ameliorated depression-like behaviors in the chronic social defeat stress depression model via modulation of Dectin-1 and the innate immune system.
Translation of GGC repeat expansions into a toxic polyglycine protein in NIID defines a novel class of human genetic disorders: The polyG diseases.
A Novel Rat Model with Long Range Optic Nerve Injury to Study Retinal Ganglion Cells Endogenous Regeneration.
Edaravone attenuates H(2)O(2) or glutamate-induced toxicity in hippocampal neurons and improves AlCl(3)/D-galactose induced cognitive impairment in mice.
Effect of the interference with DRP1 expression on the biological characteristics of glioma stem cells.
Resveratrol attenuates manganese-induced oxidative stress and neuroinflammation through SIRT1 signaling in mice.
C-phycocyanin Mitigates Cognitive Impairment in Doxorubicin-Induced Chemobrain: Impact on Neuroinflammation, Oxidative Stress, and Brain Mitochondrial and Synaptic Alterations.
Effects of the histone acetylase inhibitor C646 on growth and differentiation of adipose-derived stem cells.
Parvalbumin interneuron-mediated neural disruption in an animal model of postintensive care syndrome: prevention by fluoxetine.
Annexin A1 Attenuates Neutrophil Migration and IL-6 Expression through Fpr2 in a Mouse Model of Streptococcus suis-Induced Meningitis.
Dicer1 promotes Aβ clearance via blocking B2 RNA-mediated repression of apolipoprotein E.
Gisenoside Rg1 attenuates cadmium-induced neurotoxicity in vitro and in vivo by attenuating oxidative stress and inflammation.
Flow cytometry analysis of immune and glial cells in a trigeminal neuralgia rat model.
Astaxanthin alleviates neuropathic pain by inhibiting the MAPKs and NF-κB pathways.
Proinflammatory Pathways Are Activated in the Human Q344X Rhodopsin Knock-In Mouse Model of Retinitis Pigmentosa.
Phytogalactolipid dLGG Inhibits Mouse Melanoma Brain Metastasis through Regulating Oxylipin Activity and Re-Programming Macrophage Polarity in the Tumor Microenvironment.
Melatonin prevents diabetes-associated cognitive dysfunction from microglia-mediated neuroinflammation by activating autophagy via TLR4/Akt/mTOR pathway.
Reduction of Autophagosome Overload Attenuates Neuronal Cell Death After Traumatic Brain Injury.
Chemogenetic Activation of CX3CR1-Expressing Spinal Microglia Using Gq-DREADD Elicits Mechanical Allodynia in Male Mice.
Involvement of Oxytocin Receptor/Erk/MAPK Signaling in the mPFC in Early Life Stress-Induced Autistic-Like Behaviors.
Cdk5 Inhibitory Peptide Prevents Loss of Neurons and Alleviates Behavioral Changes in p25 Transgenic Mice.
SerpinA3N deficiency deteriorates impairments of learning and memory in mice following hippocampal stab injury.
Ginsenoside-Rg1 Rescues Stress-Induced Depression-Like Behaviors via Suppression of Oxidative Stress and Neural Inflammation in Rats.
The Protective Effect of Adiponectin-Transfected Endothelial Progenitor Cells on Cognitive Function in D-Galactose-Induced Aging Rats.
Biological and Proteomic Characteristics of an Immortalized Human Pancreatic Stellate Cell Line.
RNA-seq analysis of gene expression profiles in isolated stria vascularis from wild-type and Alport mice reveals key pathways underling Alport strial pathogenesis.
Prolonged inflammation leads to ongoing damage after spinal cord injury.
Resveratrol Preincubation Enhances the Therapeutic Efficacy of hUC-MSCs by Improving Cell Migration and Modulating Neuroinflammation Mediated by MAPK Signaling in a Mouse Model of Alzheimer's Disease.
Olanzapine-Induced Activation of Hypothalamic Astrocytes and Toll-Like Receptor-4 Signaling via Endoplasmic Reticulum Stress Were Related to Olanzapine-Induced Weight Gain.
N-Acetylcysteine Rescues Hippocampal Oxidative Stress-Induced Neuronal Injury via Suppression of p38/JNK Signaling in Depressed Rats.
Time-Dependent Impairment of Fear Conditioning and Associated Brain Regions After Pilocarpine-Induced Status Epilepticus.
Dl-3-n-Butylphthalide Promotes Remyelination and Suppresses Inflammation by Regulating AMPK/SIRT1 and STAT3/NF-κB Signaling in Chronic Cerebral Hypoperfusion.
Chemogenetic Regulation of CX3CR1-Expressing Microglia Using Gi-DREADD Exerts Sex-Dependent Anti-Allodynic Effects in Mouse Models of Neuropathic Pain.
C-X-C Motif Chemokine 10 Contributes to the Development of Neuropathic Pain by Increasing the Permeability of the Blood-Spinal Cord Barrier.
Neuroprotective Effects of Fluoxetine Against Chronic Stress-Induced Neural Inflammation and Apoptosis: Involvement of the p38 Activity.
Knockdown of TXNDC9 induces apoptosis and autophagy in glioma and mediates cell differentiation by p53 activation.
Cell therapy for spinal cord injury by using human iPSC-derived region-specific neural progenitor cells.
Obesity Worsens Gulf War Illness Symptom Persistence Pathology by Linking Altered Gut Microbiome Species to Long-Term Gastrointestinal, Hepatic, and Neuronal Inflammation in a Mouse Model.
Neural network disturbance in the medial prefrontal cortex might contribute to cognitive impairments induced by neuroinflammation.
Liraglutide Up-regulation Thioredoxin Attenuated Müller Cells Apoptosis in High Glucose by Regulating Oxidative Stress and Endoplasmic Reticulum Stress.
Caspase inhibition rescues F1Fo ATP synthase dysfunction-mediated dendritic spine elimination.
Loss of TDP-43 in astrocytes leads to motor deficits by triggering A1-like reactive phenotype and triglial dysfunction.
Non-neuronal crosstalk promotes an inflammatory response in nodose ganglia cultures after exposure to byproducts from gram positive, high-fat-diet-associated gut bacteria.
Inhibition of the NLRP3-inflammasome prevents cognitive deficits in experimental autoimmune encephalomyelitis mice via the alteration of astrocyte phenotype.
Cathodal tDCS exerts neuroprotective effect in rat brain after acute ischemic stroke.
Effect of AQP4-RNAi in treating traumatic brain edema: Multi-modal MRI and histopathological changes of early stage edema in a rat model.
Carbon dot targeting to nitrogen signaling molecules for inhibiting neuronal death.
Ghrelin promotes neural differentiation of adipose tissue-derived mesenchymal stem cell via AKT/mTOR and β-catenin signaling pathways.
The effect of swimming exercise and diet on the hypothalamic inflammation of ApoE-/- mice based on SIRT1-NF-κB-GnRH expression.
Excretory/secretory products of Angiostrongylus cantonensis fifth-stage larvae induce endoplasmic reticulum stress via the Sonic hedgehog pathway in mouse astrocytes.
Polydopamine/carboxylic graphene oxide-composited polypyrrole films for promoting adhesion and alignment of Schwann cells.
Protection of the Geum japonicum Thunb. var. chinense extracts against oxygen-glucose deprivation and re-oxygenation induced astrocytes injury via BDNF/PI3K/Akt/CREB pathway.
Scorpion alleviates bone cancer pain through inhibition of bone destruction and glia activation.
Elevated lymphocyte specific protein 1 expression is involved in the regulation of leukocyte migration and immunosuppressive microenvironment in glioblastoma.
Neuroinflammation induced by secretion of acetylated HMGB1 from activated microglia in hippocampi of mice following chronic cold exposure.
Silencing of circular RNA HIPK2 in neural stem cells enhances functional recovery following ischaemic stroke.
Resveratrol Downregulates STAT3 Expression and Astrocyte Activation in Primary Astrocyte Cultures of Rat.
Effects of circadian rhythm disorder on the hippocampus of SHR and WKY rats.
Photobiomodulation therapy for repeated closed head injury in rats.
The Pattern of AQP4 Expression in the Ageing Human Brain and in Cerebral Amyloid Angiopathy.
GABA-mediated activated microglia induce neuroinflammation in the hippocampus of mice following cold exposure through the NLRP3 inflammasome and NF-κB signaling pathways.
Small molecular compounds efficiently convert human fibroblasts directly into neurons.
Donepezil-induced oligodendrocyte differentiation is mediated through estrogen receptors.
Zika virus promotes CCN1 expression via the CaMKIIα-CREB pathway in astrocytes.
Cryogen spray cooling mitigates inflammation and injury-induced CISD2 decline in rat spinal cord hemisection model.
Neuroprotective effects and mechanisms of action of nicotinamide mononucleotide (NMN) in a photoreceptor degenerative model of retinal detachment.
Evaluating the Cytotoxicity of Ti(3)C(2) MXene to Neural Stem Cells.
Silencing IFNγ inhibits A1 astrocytes and attenuates neurogenesis decline and cognitive impairment in endotoxemia.
Spider venom components decrease glioblastoma cell migration and invasion through RhoA-ROCK and Na(+)/K(+)-ATPase β2: potential molecular entities to treat invasive brain cancer.
Perinatal exposure to nonylphenol delayed myelination in offspring cerebellum.
Antidepressant-like Effect of Merazin Hydrate Depends on NO/ERK by Suppressing Its Downstream NF-κB or Nonactivating CREB/BDNF in Mouse Hippocampus.
Upregulation of miRNA-9-5p Promotes Angiogenesis after Traumatic Brain Injury by Inhibiting Ptch-1.
PPARα-Dependent Effects of Palmitoylethanolamide Against Retinal Neovascularization and Fibrosis.
[Establishment of a vimentin knockout and HIV-1 gp120 transgenic mouse model].
Local Serpin Treatment via Chitosan-Collagen Hydrogel after Spinal Cord Injury Reduces Tissue Damage and Improves Neurologic Function.
Metal ion-responsive nanocarrier derived from phosphonated calix[4]arenes for delivering dauricine specifically to sites of brain injury in a mouse model of intracerebral hemorrhage.
Doxorubicin-polyglycerol-nanodiamond conjugates disrupt STAT3/IL-6-mediated reciprocal activation loop between glioblastoma cells and astrocytes.
Chlorogenic acid effectively treats cancers through induction of cancer cell differentiation.
Sailuotong Capsule Prevents the Cerebral Ischaemia-Induced Neuroinflammation and Impairment of Recognition Memory through Inhibition of LCN2 Expression.
C(18)H(17)NO(6) and Its Combination with Scutellarin Suppress the Proliferation and Induce the Apoptosis of Human Glioma Cells via Upregulation of Fas-Associated Factor 1 Expression.
Decreased immunoglobulin G in brain regions of elder female APOE4-TR mice accompany with Aβ accumulation.
Myelin Damage in Diffuse Axonal Injury.
BAF45D Downregulation in Spinal Cord Ependymal Cells Following Spinal Cord Injury in Adult Rats and Its Potential Role in the Development of Neuronal Lesions.
Expression of cysteinyl leukotriene receptor in brain tissues of rats with Streptococcus pneumoniae meningitis.
Evidence for Sexual Dimorphism in the Response to TLR3 Activation in the Developing Neonatal Mouse Brain: A Pilot Study.
Folic acid improves abnormal behavior via mitigation of oxidative stress, inflammation, and ferroptosis in the BTBR T+ tf/J mouse model of autism.
Melatonin alleviates cognition impairment by antagonizing brain insulin resistance in aged rats fed a high-fat diet.
Ellagic acid supports neuron by regulating astroglia Nrf2.
Long non-coding RNA linc00645 promotes TGF-β-induced epithelial-mesenchymal transition by regulating miR-205-3p-ZEB1 axis in glioma.
Geraniin Attenuates Lipopolysaccharide-Induced Cognitive Impairment in Mice by Inhibiting Toll-Like Receptor 4 Activation.
Circular RNA TLK1 Aggravates Neuronal Injury and Neurological Deficits after Ischemic Stroke via miR-335-3p/TIPARP.
Activation of mitogen-activated protein kinases in satellite glial cells of the trigeminal ganglion contributes to substance P-mediated inflammatory pain.
Cordycepin (3'-deoxyadenosine) promotes remyelination via suppression of neuroinflammation in a cuprizone-induced mouse model of demyelination.
Glutaminyl cyclase inhibitor exhibits anti-inflammatory effects in both AD and LPS-induced inflammatory model mice.
Antinociceptive effect of isoorientin against neuropathic pain induced by the chronic constriction injury of the sciatic nerve in mice.
Propentofylline reduces mechanical allodynia and induces mitogen-activated protein kinase phosphatase-1: An experimental study in a rat model of acute incisional pain.
Protective effect of 4-Methoxy benzyl alcohol on the neurovascular unit after cerebral ischemia reperfusion injury.
Nanozyme-Based Bandage with Single-Atom Catalysis for Brain Trauma.
P2Y(14) receptor is functionally expressed in satellite glial cells and mediates interleukin-1β and chemokine CCL2 secretion.
Magnolol exhibits anti-inflammatory and neuroprotective effects in a rat model of intracerebral haemorrhage.
Modulation of α-adrenoceptor signalling protects photoreceptors after retinal detachment by inhibiting oxidative stress and inflammation.
Combinatory FK506 and Minocycline Treatment Alleviates Prion-Induced Neurodegenerative Events via Caspase-Mediated MAPK-NRF2 Pathway.
AKR1B10 (Aldo-keto reductase family 1 B10) promotes brain metastasis of lung cancer cells in a multi-organ microfluidic chip model.
Effects of astrocyte on neuronal outgrowth in a layered 3D structure.
Toxicity mechanism of sevoflurane in neural stem cells of rats through DNA methylation.
GABA(B) receptor activation attenuates inflammatory orofacial pain by modulating interleukin-1β in satellite glial cells: Role of NF-κB and MAPK signaling pathways.
Chondroitin sulfate proteoglycan represses neural stem/progenitor cells migration via PTPσ/α-actinin4 signaling pathway.
Chronic mild hypoxia promotes hippocampal neurogenesis involving Notch1 signaling in epileptic rats.
The DosR antigen Rv1737c from Mycobacterium tuberculosis confers inflammation regulation in tuberculosis infection.
PRRT2 deficiency induces paroxysmal kinesigenic dyskinesia by influencing synaptic function in the primary motor cortex of rats.
HMGB1-mediated differential response on hippocampal neurotransmitter disorder and neuroinflammation in adolescent male and female mice following cold exposure.
Redox Trimetallic Nanozyme with Neutral Environment Preference for Brain Injury.
Microglia as modulators of exosomal alpha-synuclein transmission.
Overriding FUS autoregulation in mice triggers gain-of-toxic dysfunctions in RNA metabolism and autophagy-lysosome axis.
Pseudovirus rVSVΔG-ZEBOV-GP Infects Neurons in Retina and CNS, Causing Apoptosis and Neurodegeneration in Neonatal Mice.
Possible mechanisms of prenatal cold stress induced-anxiety-like behavior depression in offspring rats.
Melatonin receptor activation provides cerebral protection after traumatic brain injury by mitigating oxidative stress and inflammation via the Nrf2 signaling pathway.
Resveratrol suppresses the myofibroblastic phenotype and fibrosis formation in kidneys via proliferation-related signalling pathways.
The P2Y(14) receptor in the trigeminal ganglion contributes to the maintenance of inflammatory pain.
The glutamatergic system and astrocytic impairment in rat hippocampus: a comparative study of underlying etiology and pathophysiology of depression.
Silencing of microRNA-146a alleviates the neural damage in temporal lobe epilepsy by down-regulating Notch-1.
Folic Acid Decreases Astrocyte Apoptosis by Preventing Oxidative Stress-Induced Telomere Attrition.
I-8, a novel inhibitor of mutant IDH1, inhibits cancer progression in vitro and in vivo.
GA-binding protein GABPβ1 is required for the proliferation of neural stem/progenitor cells.
Astroglial dysfunctions drive aberrant synaptogenesis and social behavioral deficits in mice with neonatal exposure to lengthy general anesthesia.
Neuroprotective effects of an engineered commensal bacterium in the 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine Parkinson disease mouse model via producing glucagon-like peptide-1.
Microglia Activated by Excess Cortisol Induce HMGB1 Acetylation and Neuroinflammation in the Hippocampal DG Region of Mice Following Cold Exposure.
miR-504 suppresses mesenchymal phenotype of glioblastoma by directly targeting the FZD7-mediated Wnt-β-catenin pathway.
Icariin attenuates neuroinflammation and exerts dopamine neuroprotection via an Nrf2-dependent manner.
Ginkgo biloba Extract Inhibits Astrocytic Lipocalin-2 Expression and Alleviates Neuroinflammatory Injury via the JAK2/STAT3 Pathway After Ischemic Brain Stroke.
Yi-nao-jie-yu Prescription Exerts a Positive Effect on Neurogenesis by Regulating Notch Signals in the Hippocampus of Post-stroke Depression Rats.
Neuroprotective Effects of Ginsenoside-Rg1 Against Depression-Like Behaviors via Suppressing Glial Activation, Synaptic Deficits, and Neuronal Apoptosis in Rats.
Skull optical clearing window for in vivo imaging of the mouse cortex at synaptic resolution.
Glia Maturation Factor and Mast Cell-Dependent Expression of Inflammatory Mediators and Proteinase Activated Receptor-2 in Neuroinflammation.
Neuroprotective Effects of Curcumin on IL-1β-Induced Neuronal Apoptosis and Depression-Like Behaviors Caused by Chronic Stress in Rats.
Honokiol Ameliorates Amyloidosis and Neuroinflammation and Improves Cognitive Impairment in Alzheimer's Disease Transgenic Mice.
Curcumin attenuates chronic intermittent hypoxia-induced brain injuries by inhibiting AQP4 and p38 MAPK pathway.
GABAB receptor mediate hippocampal neuroinflammation in adolescent male and female mice after cold expose.
Bexarotene protects against neurotoxicity partially through a PPARγ-dependent mechanism in mice following traumatic brain injury.
Decreased expression of LATS1 correlates with astrogliosis after spinal cord injury.
Deficiency in augmenter of liver regeneration accelerates liver fibrosis by promoting migration of hepatic stellate cell.
Beneficial Effects of Exercise Pretreatment in a Sporadic Alzheimer's Rat Model.
N-methyl D-aspartate receptor subtype 2B antagonist, Ro 25-6981, attenuates neuropathic pain by inhibiting postsynaptic density 95 expression.
A model to study complement involvement in experimental retinal degeneration.
Early Postnatal Exposure to Airborne Fine Particulate Matter Induces Autism-like Phenotypes in Male Rats.
Knockdown of Ski decreased the reactive astrocytes proliferation in vitro induced by oxygen-glucose deprivation/reoxygenation.
Transplantation of hypoxic preconditioned neural stem cells benefits functional recovery via enhancing neurotrophic secretion after spinal cord injury in rats.
Tert-butylhydroquinone post-treatment attenuates neonatal hypoxic-ischemic brain damage in rats.
Glia maturation factor beta is required for reactive gliosis after traumatic brain injury in zebrafish.
ZDHHC8 critically regulates seizure susceptibility in epilepsy.
Tick-Borne Encephalitis Virus Nonstructural Protein NS5 Induces RANTES Expression Dependent on the RNA-Dependent RNA Polymerase Activity.
Photobiomodulation therapy promotes neurogenesis by improving post-stroke local microenvironment and stimulating neuroprogenitor cells.
Long-term treadmill exercise attenuates Aβ burdens and astrocyte activation in APP/PS1 mouse model of Alzheimer's disease.
Neuroprotective Effect of Anethole Against Neuropathic Pain Induced by Chronic Constriction Injury of the Sciatic Nerve in Mice.
Dietary eicosapentaenoic acid normalizes hippocampal omega-3 and 6 polyunsaturated fatty acid profile, attenuates glial activation and regulates BDNF function in a rodent model of neuroinflammation induced by central interleukin-1β administration.
Reversal of pancreatic desmoplasia by re-educating stellate cells with a tumour microenvironment-activated nanosystem.
Effect of tumor necrosis factor-α on the expression of the ammonia transporter Rhcg in the brain in mice with acute liver failure.
Expressions of nestin and glial fibrillary acidic protein in rat retina after optic nerve transection.
Intranasal Delivery of a Caspase-1 Inhibitor in the Treatment of Global Cerebral Ischemia.
An Increase of Sigma-1 Receptor in the Penumbra Neuron after Acute Ischemic Stroke.
Neuroprotective Effect of Chitosan Oligosaccharide on Hypoxic-Ischemic Brain Damage in Neonatal Rats.
Discovery of Aquaporin-1 and Aquaporin-4 Expression in an Intramedullary Spinal Cord Ependymal Cyst: Case Report.
Chronic metformin treatment facilitates seizure termination.
Inhibition of Blood-Brain Barrier Disruption by an Apolipoprotein E-Mimetic Peptide Ameliorates Early Brain Injury in Experimental Subarachnoid Hemorrhage.
Human Umbilical Cord Mesenchymal Stem Cells Overexpressing Nerve Growth Factor Ameliorate Diabetic Cystopathy in Rats.
The role of sodium hydrosulfide in attenuating the aging process via PI3K/AKT and CaMKKβ/AMPK pathways.
Early Minocycline and Late FK506 Treatment Improves Survival and Alleviates Neuroinflammation, Neurodegeneration, and Behavioral Deficits in Prion-Infected Hamsters.
Expression of Signaling Molecules in Progressive Multifocal Leukoencephalopathy.
Effects of oxidative stress on hyperglycaemia-induced brain malformations in a diabetes mouse model.
Oligodendroglial deletion of ESCRT-I component TSG101 causes spongiform encephalopathy.
Poly-L-ornithine enhances migration of neural stem/progenitor cells via promoting α-Actinin 4 binding to actin filaments.
Formylpeptide Receptors Promote the Migration and Differentiation of Rat Neural Stem Cells.
Intrathecal Injection of Human Umbilical Cord-Derived Mesenchymal Stem Cells Ameliorates Neuropathic Pain in Rats.
Potential implications of Apolipoprotein E in early brain injury after experimental subarachnoid hemorrhage: Involvement in the modulation of blood-brain barrier integrity.
Endoplasmic reticulum stress mediates JNK-dependent IRS-1 serine phosphorylation and results in Tau hyperphosphorylation in amyloid β oligomer-treated PC12 cells and primary neurons.
Neural stem/progenitor cells react to non-glial cns neoplasms.
The Neuropilin-1 Inhibitor, ATWLPPR Peptide, Prevents Experimental Diabetes-Induced Retinal Injury by Preserving Vascular Integrity and Decreasing Oxidative Stress.
Deficiency of macrophage migration inhibitory factor attenuates tau hyperphosphorylation in mouse models of Alzheimer's disease.
Poly-L-ornithine promotes preferred differentiation of neural stem/progenitor cells via ERK signalling pathway.
Disrupted SOX10 function causes spongiform neurodegeneration in gray tremor mice.
An immortalized rat pancreatic stellate cell line RP-2 as a new cell model for evaluating pancreatic fibrosis, inflammation and immunity.
Severely exacerbated neuromyelitis optica rat model with extensive astrocytopathy by high affinity anti-aquaporin-4 monoclonal antibody.
Limb remote ischemic postconditioning protects cerebral ischemia from injury associated with expression of HIF-1α in rats.
Remote ischemic post-conditioning improves neurological function by AQP4 down-regulation in astrocytes.
The positive effects of Ginsenoside Rg1 upon the hematopoietic microenvironment in a D-Galactose-induced aged rat model.
Ginsenoside Rg1 prevents cognitive impairment and hippocampus senescence in a rat model of D-galactose-induced aging.
Photoreceptor degeneration, structural remodeling and glial activation: a morphological study on a genetic mouse model for pericyte deficiency.
Increased expression of Notch1 in temporal lobe epilepsy: animal models and clinical evidence.
Puerarin protected the brain from cerebral ischemia injury via astrocyte apoptosis inhibition.
Effects of phlorizin on diabetic retinopathy according to isobaric tags for relative and absolute quantification-based proteomics in db/db mice.
Contribution of SATB2 to the stronger osteogenic potential of bone marrow stromal cells from craniofacial bones.
Further assessment of neuropathology in retinal explants and neuroprotection by human neural progenitor cells.
Progranulin is expressed within motor neurons and promotes neuronal cell survival.
Zhou D, Yang X, Song L, Wu M, Zhang H, Cao JL, Min S
Frontiers in pharmacology 2026;17:1759544
Frontiers in pharmacology 2026;17:1759544
Chronic intermittent hypoxia increases Parkinson's disease susceptibility via PPARα-mediated lipid droplet-mitochondrial dysfunction.
Zhai MR, Pan J, Wu ZH, He YY, Zhang KR, Ren L, Wang YR, Li YB, Gao J, Xiao L, Liu YH
Theranostics 2026;16(5):2466-2487
Theranostics 2026;16(5):2466-2487
Flavonoids of Ziziphora clinopodioides improve Alzheimer's cognitive impairment and inhibit NLRP3 inflammasome activation via autophagy-lysosome pathway.
Gu L, Liu J, Shan X, Li S, Zheng M, Wang C, Tan Y, Zhuo X, Li Q, Yang W, Zhang X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 May;154:158028
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 May;154:158028
The C3-C3aR axis drives rotenone-induced cognitive damage via synaptic engulfment, dark microglia and PANoptosis.
Liu J, Hou L, Ma Y, Tian L, Hong JS, Zhao J, Wang Q
Redox biology 2026 Mar;90:104062
Redox biology 2026 Mar;90:104062
Glaucine suppresses IL-16/CD4 to alleviate neuropathic pain via spinal p56(lck)-NMDA receptor signaling.
Li X, Wang R, Ma X, Yang J, Zhang S, Zhang Z, Jiang H, Liu J, Yu B, Dai W
Naunyn-Schmiedeberg's archives of pharmacology 2026 Mar;399(5):6485-6500
Naunyn-Schmiedeberg's archives of pharmacology 2026 Mar;399(5):6485-6500
c-MAF Transcriptionally Activates Slc40a1 to Repress Ferroptosis in Sepsis-Associated Encephalopathy.
Song W, Shen Q, Zhang H, Bu X, Gao W, Wang W
CNS neuroscience & therapeutics 2026 Mar;32(3):e70820
CNS neuroscience & therapeutics 2026 Mar;32(3):e70820
Early-life inflammation increases aggressive behavior in adult male mice through an astrocyte-neuron signaling.
Wang J, Wang J, Chen H, Gao F, Xu R, Lv Y, Ding S, Li F, Li X, Shi Y, Wei H, Chen X, Zhao J, Xiong J, Li X, Zhao L, Meng QT, Xiao X, Wang ZH
Molecular psychiatry 2026 Mar;31(3):1455-1474
Molecular psychiatry 2026 Mar;31(3):1455-1474
DPEP2 suppresses hyperinflammation via metabolic reprogramming of macrophages in sepsis.
Luo W, Xu W, Yin Q, Song J, Wang J, Guan Y, Huang J, Yu J, Zou K, Jin D, Xu C, Qiu M, Qiu Z, Zhong J
Nature communications 2026 Mar 9;17(1)
Nature communications 2026 Mar 9;17(1)
Reprogramming of neuronal genome function and phenotype by astrocytes.
Li B, Hagy KT, Safi A, Beer MA, Barrera A, Geraghty S, Rai R, Pederson AN, Reisman SJ, Love MI, Sullivan PF, Eroglu C, Crawford GE, Gersbach CA
bioRxiv : the preprint server for biology 2026 Mar 7;
bioRxiv : the preprint server for biology 2026 Mar 7;
Upregulation of T-type voltage-dependent Ca²⁺ channels in activated hepatic stellate cells promotes liver fibrosis in metabolic dysfunction-associated steatohepatitis.
Kawata N, Kondo R, Hashizume M, Suzuki Y, Yamamura H
Pflugers Archiv : European journal of physiology 2026 Mar 31;478(4)
Pflugers Archiv : European journal of physiology 2026 Mar 31;478(4)
Sphingosine-1-Phosphate Receptor 3 Mediated Neuroinflammation is Critically Involved in the Development of Brain Injury Following Cardiac Arrest in Mice.
Wang X, Cai SQ, Gao Y, Fan JJ, Ren LW, Gao HC, Chen XD, Duan ML
Neurochemical research 2026 Mar 19;51(2)
Neurochemical research 2026 Mar 19;51(2)
A Ratiometric Afterglow Luminescence Probe for in Vivo Imaging of Neuroinflammation in Traumatic Brain Injury.
Deng L, Xiang J, Zeng X, Li Z, Chen Z, Zhang C, He H, Ye T, Gong Q, Song G, Liang C
Analytical chemistry 2026 Mar 17;98(10):7877-7887
Analytical chemistry 2026 Mar 17;98(10):7877-7887
Blood-brain barrier-penetrative lipid nanoparticles enable systemic delivery of TRIM11 mRNA to disaggregate Tau in Alzheimer's disease models.
Zou Y, Sang Y, Zheng M, Shi B
Cell reports. Medicine 2026 Mar 17;7(3):102685
Cell reports. Medicine 2026 Mar 17;7(3):102685
Adipose tissue-derived stromal cells enhance glycolytic metabolism in injured nerve cells via the FOXK1-HK2 axis for spinal cord injury repair.
Li F, Li H, Jia Y, Ou L, Fang Y, Pan L, Liu H, Ning B
Journal of translational medicine 2026 Mar 17;24(1)
Journal of translational medicine 2026 Mar 17;24(1)
Tanshinone IIA-pretreated mesenchymal stem cells alleviate neuroinflammation in 3×Tg-AD mice via the TREM2/PI3K/Akt pathway.
Wu J, Ge Y, Zhang L, Huang J, Huang N, Luo Y
Stem cell research & therapy 2026 Mar 17;17(1)
Stem cell research & therapy 2026 Mar 17;17(1)
CRP Deficiency Rescues Periodontitis-Induced Hippocampal Neurogenesis Impairment by Suppressing OPC-Derived BMP4 Signaling in Rats.
Li L, Deng P, Hou S, Xia X, Zhao W, Zhu X, Zhang Y, Wang C, Xu L, Song J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar 17;:e16199
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar 17;:e16199
Evodiamine alleviates MPTP-induced Parkinson's disease in mice by regulating gut microbiota and suppressing TLR4/MyD88/NF-kB pathway.
Wang S, Zhu Y, Wang J, Jin W, Li N, Li Z, Chang Y, Jiang C, Wang T
Scientific reports 2026 Mar 13;16(1)
Scientific reports 2026 Mar 13;16(1)
Roudoukou-Suanzaoren Ameliorates Chronic Restraint-Induced Anxiety- and Depression-Like Behaviors in Mice via the Gut-Brain Axis.
Wang X, Xu J, Li M, Du L, Wang C, Zhang C
Journal of agricultural and food chemistry 2026 Mar 11;74(9):7607-7620
Journal of agricultural and food chemistry 2026 Mar 11;74(9):7607-7620
Mechanism of Qufeng Huoxue decoction in treating paclitaxel-induced peripheral neuropathy based on network pharmacology and molecular docking.
Ao G, Shu D, Xu L, Liu X, Sheng J, Jiang Z, Han Z, Ruan F, Wang X, Hua Z
Neuropeptides 2026 Mar 11;117:102608
Neuropeptides 2026 Mar 11;117:102608
Enteric gliosis induced by TRPV4 alleviates intestinal excessive-motility through Ca(2+) signaling.
Tan Q, Li T, Xie H, Chen Y, Chen S, Xu C, Yang F, Dong H, Chen J, Xiao W
Neuropharmacology 2026 Mar 1;285:110807
Neuropharmacology 2026 Mar 1;285:110807
Triamcinolone acetonide nanoparticles ameliorate interstitial cystitis and anxiety/depression by targeting the bladder-metabolic-brain axis.
Liu Z, Ju Q, Yang Y, Lu Q, Huang R, Yang J, Bao Y, Jiang T, Peng Y, Liu Y, Zhang D, Shen W
Materials today. Bio 2026 Jun;38:103112
Materials today. Bio 2026 Jun;38:103112
Electroacupuncture as a promising therapeutic strategy for chronic constriction injury-induced neuropathic pain: Insights into the PPARα/SIRT1/NF-κB axis.
Jia P, Chen Y, Wu Q, Zhang R, Jabeen T, Du Y, Lei L, Duan S, Chen A, Yin L, Jiang S
Colloids and surfaces. B, Biointerfaces 2026 Jun;262:115546
Colloids and surfaces. B, Biointerfaces 2026 Jun;262:115546
Bufotenidine attenuates astrocyte ferroptosis in depressive-like behaviors through targeting GluA1 to reduce neuronal lipid synthesis.
Wu W, Chen Z, Xu Y, Xie X, Tan A, Hu M, Xu D, Lv X, Chen W, Zhou J, Zhu Y, Ma H
Free radical biology & medicine 2026 Jun;249:589-602
Free radical biology & medicine 2026 Jun;249:589-602
STAT3 inhibition ameliorates cognitive dysfunction in type 2 diabetes mellitus by modulating astrocytes via Nrf2 pathway activation.
Wang J, Chen P, Li Y, Wang R, Ding W, Yu R, Qin Q, Wu R, Wei W, Shi J, Yuan H, Zhuang C, Sun Y
Free radical biology & medicine 2026 Jun;249:165-179
Free radical biology & medicine 2026 Jun;249:165-179
Modified Kai-Xin-San ameliorates cognitive impairment in Alzheimer's disease model mice by regulating neuroinflammation and synaptic dysfunction.
Liu XY, Wang K, Zhong JJ, Lin CL, Zhu JR, Wang PP, Guo R, Shao SS, Lim HSD, Siow KL, Shan Kek R, Ng YH, Chen M, Han RC, Yao H, Zheng GQ, Wen L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jun;155:158102
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jun;155:158102
Sex-dependent impact of Il6 deficiency in Parkinson's disease mice.
Chen F, Duan Y, Wang M, Liu Z, Zhao J, Fan G, He Y, Dong H, Zhang X, Fang R, Zhang Y, Yan X, Shen C, Tang X, Ma Y, Yu M, Zhou R, Fei J, Huang F
Genes & diseases 2026 Jul;13(4):101986
Genes & diseases 2026 Jul;13(4):101986
Design, synthesis, and biological evaluation of pyranone-carbamate hybrids as selective butyrylcholinesterase inhibitors with anti-neuroinflammatory activity for Alzheimer's disease.
Liu X, Xu J, Lin C, Gao X, Xie Y, Chen X, Huang Q, Ye R, Shi H, Zhang L, Ye ZC, Wu C, Zha D
Bioorganic chemistry 2026 Jul 15;176:109887
Bioorganic chemistry 2026 Jul 15;176:109887
A mitochondria-targeted idebenone derivative W1a mitigates cerebral ischemia-reperfusion injury by preserving mitochondrial integrity and suppressing neuroinflammation.
Li M, Kong D, Ren Q, Li Z, Wang Z, Bai Z, Meng L, Liu X, Yang Z, Wu G
Bioorganic chemistry 2026 Jan;168:109356
Bioorganic chemistry 2026 Jan;168:109356
BTLA-mediated regulation of neuroimmune responses enhances recovery after intracerebral hemorrhage.
Wu Y, Zhang Y, Fu P, Huang M, Chen S, Li Y, Wu T, Rastegar-Kashkooli Y, Cheng N, Zhao T, Wang Y, Wang X, Wang J, Wang J, Jiang C
Journal of neuroinflammation 2026 Jan 23;23(1):69
Journal of neuroinflammation 2026 Jan 23;23(1):69
Neuroprotective Effects of Desert Milk Exosomes in LPS-Induced Cognitive Decline: Role of Microglial M2 Polarization and AMPK Signaling.
Li Y, Lu W, Qian W, Liao X, Wang P, Wang Y, Jiao W, Wang M, Zhao J, Yang J, Gao H, Li H
Nutrients 2026 Jan 19;18(2)
Nutrients 2026 Jan 19;18(2)
Development of a Novel Extracellular Vesicle-Based Biomarker Approach for Pediatric High-Grade Glioma.
Fernandez Garcia A, Iyer P, Ashi P, Tella I, Sangaraboina V, Bhagat D, Janarthanam C, Bargues-Carot A, Kanthasamy AG, Spoerer T, Golan ME, Stice SL, Funato K
Journal of extracellular biology 2026 Feb;5(2):e70117
Journal of extracellular biology 2026 Feb;5(2):e70117
Glycyrrhizic acid-loaded biomimetic hybrid liposomes targeting inflammatory cascades and PD-1/PD-L1 pathway to reverse neuroinflammation-driven cognitive decline.
Wang Y, Luo F, Zhang P, Niu H, Tan Y, Zhang Y, Tang Z, Du L, Jin Y, Jin X
Materials today. Bio 2026 Feb;36:102657
Materials today. Bio 2026 Feb;36:102657
Astrocytic PYGM attenuates tau pathology by promoting lactate-mediated neuroprotection.
Cao J, Meng J, Chen Y, Tang Z, Wang Y, Li K, Zhang X, Luo H, Li H, Wang Z, Zhang YW
Alzheimer's & dementia : the journal of the Alzheimer's Association 2026 Feb;22(2):e71202
Alzheimer's & dementia : the journal of the Alzheimer's Association 2026 Feb;22(2):e71202
Adenylyl Cyclase 8 in Dorsal CA1 Neurons Prevents Depressive-Like Behaviors by Maintaining Neuronal Excitability and Glutamatergic Neurotransmission Through TIP39-PTH2R Signaling.
Liu ZJ, Bi JR, Yu ZY, Tian M, Chen ZY, Wei R, Wang MM, Zha HW, Zhang YQ, Wang HJ, Qiang BY, Sun SS, Zhu XJ, Chen WB, Sun D
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Feb;13(10):e12170
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Feb;13(10):e12170
hsa_circ_0006168 drives microglial activation in TNC via miR-99b-5p/KDM6B axis to promote central sensitization in migraine.
Chen Q, Zhai Q, Lin J, Huang Y, Li H, Zhang C, Yu Q, Sun T, Pan Y
The journal of headache and pain 2026 Feb 7;27(1)
The journal of headache and pain 2026 Feb 7;27(1)
Spatial memory in Alzheimer's disease 5XFAD mice is enhanced by XPO1 inhibitor KPT-330.
Wong SQ, Ouellette A, Harrison L, McNamara A, Tam RA, Alexandrov A, Nawrocik-Madrid A, Sanchez JJ, Ginsburg BC, Andrade AA, Lapierre LR
GeroScience 2026 Feb 6;
GeroScience 2026 Feb 6;
Cognitive and Motor Dysfunction in STXBP1 R406H Mice.
Liu H, Duan YZ, Li S, Hu Y, Mao X, Cheng Y
Journal of molecular neuroscience : MN 2026 Feb 28;76(1)
Journal of molecular neuroscience : MN 2026 Feb 28;76(1)
KANK4 Regulates CXCL16 Glycosylation Through TMEM260 to Modulate Microglial Activation in Sepsis-associated Encephalopathy.
Peng M, Tan S, Li A, Guo Q, Liu L
Inflammation 2026 Feb 28;49(1)
Inflammation 2026 Feb 28;49(1)
Neonatal Spinal-Cord-Like Scaffold with Hierarchical Structural and Neurogenetic Microenvironments for Spinal Cord Injury Repair.
Bai B, Wang J, Jiang L, Zou C, Liu S, Qi Z, Zhang C, Li Z, Zhang R, Liu Y, Lu G, Song X, Li C, Zhao H, Ran N, Zhou G, Kong X, Yung PSH, Lei D, Feng S, Zhou H
ACS nano 2026 Feb 24;20(7):5423-5437
ACS nano 2026 Feb 24;20(7):5423-5437
Degradation of LOX-1 via Neuronal Autophagy Alleviates Cerebral Ischemia/Reperfusion Injury in Mice.
Hu Y, Zheng Y, Shen T, Wang R, Yan F, Tao Z, Luo Y, Liu P
Molecular neurobiology 2026 Feb 17;63(1):444
Molecular neurobiology 2026 Feb 17;63(1):444
CD300a Immunoreceptor Blocking Attenuates Neuronal Apoptosis by Regulating Efferocytosis and Promotes Hindlimb Functional Recovery after Acute Spinal Cord Injury in Mice.
Okuwaki S, Takahashi H, Nakahashi-Oda C, Sakashita K, Nakagawa T, Ogata Y, Sunami T, Shimizu T, Gamada H, Noguchi H, Miura K, Funayama T, Yamazaki M, Shibuya A, Koda M
Journal of neurotrauma 2026 Feb 17;:8977151261415619
Journal of neurotrauma 2026 Feb 17;:8977151261415619
Aquaporin-4-overexpressing mesenchymal stem cells promote neurological recovery after intracerebral hemorrhage by inhibiting TLR4/NF-κB signaling.
Li Y, Yang W, Tang Y, Tao Z, Li P, Xu B, Zhao X, Lu X
Free radical biology & medicine 2026 Feb 16;244:147-165
Free radical biology & medicine 2026 Feb 16;244:147-165
EGCG-loaded nanoparticles attenuate post-SAH white matter injury by targeting HO-1/S100A10 to suppress oxidative stress-induced reactive astrocytes.
Lang D, Zheng Y, Zhang J, Li Z, Niu M, Wang J, Wang X, Huang L, Xue J, Li L, Chen Y
Redox report : communications in free radical research 2026 Dec 31;31(1):2664955
Redox report : communications in free radical research 2026 Dec 31;31(1):2664955
Gut microbial ammonia as a mediator of PFOS neurotoxicity and its remediation by the flavonoid Icaritin.
Yi Y, Zhang W, Wei Y, Ran W, Liu D, Deng W, Duan S, Yao J, Wang L, Zhang Y, Gao J, Gong Q
Gut microbes 2026 Dec 31;18(1):2620125
Gut microbes 2026 Dec 31;18(1):2620125
Tianwang Buxin Pill improves cognitive function in APP/PS1 mice by reducing neuronal damage and regulating synaptic plasticity.
Zou F, Ren X, Huo G, Liu P, Sun C
Journal of ethnopharmacology 2026 Aug 10;367:121683
Journal of ethnopharmacology 2026 Aug 10;367:121683
Aberrant histone acetylation and dysregulated synaptic plasticity in cognitive impairment induced by a high-methionine diet.
Li J, Fu Y, Gu X, Xie Q, Liu Z, Cao Z, Li L, Ren J, Li Y, Yang H, Peng Z, Liu Z, Xie J
Neural regeneration research 2026 Aug 1;21(8):3842-3853
Neural regeneration research 2026 Aug 1;21(8):3842-3853
Intermittent theta-burst stimulation promotes neurovascular unit remodeling after ischemic stroke in a mouse model.
Zhang J, Ding M, Luo L, Huang D, Li S, Chen S, Fan Y, Liu L, Xie H, Liu G, Yu K, Wu J, Xiao X, Wu Y
Neural regeneration research 2026 Aug 1;21(8):3598-3608
Neural regeneration research 2026 Aug 1;21(8):3598-3608
Neuro-bone-skin tri-regeneration via a microenvironment-responsive PRP-loaded chitosan hydrogel for traumatic brain injury therapy.
Yang W, Su Y, Wang H, Liu P, Cheng P, Zhao H, He Y, Liu Y, Ma S, Guan F, Yao M
Materials today. Bio 2026 Apr;37:102913
Materials today. Bio 2026 Apr;37:102913
Dual-responsive PDA-HP hydrogel enables mitochondria-targeted mild photothermal therapy for spinal cord repair.
Li Y, Hu J, Ran B, Zhong H, Zhong N, Zhong Y, Fu X, Liu X, Wu G, Zhong Q, Li J
Materials today. Bio 2026 Apr;37:102783
Materials today. Bio 2026 Apr;37:102783
Microalgae-MOF integrated drug delivery system for cranial radiotherapy and chemotherapy-induced brain injury.
Li X, Ye J, Zhong D, Xie J, Ding Z, Zhou M
Biomaterials 2026 Apr;327:123767
Biomaterials 2026 Apr;327:123767
IMR-1 ameliorates perinatal LPS-induced brain injury by promoting the conversion of glial cells into neurons.
Tang J, Zhou S, Zhang Z, Duan B, Xu Y
Journal of molecular histology 2026 Apr 27;57(3)
Journal of molecular histology 2026 Apr 27;57(3)
Electroacupuncture Stimulation of the Head Motor Area Alleviates Brain Cell Pyroptosis and Neurobehaviors in Stroke Rats Through the NF-κB/NLRP3 Signaling Axis.
Hu Z, Yong Z
Neurochemical research 2026 Apr 27;51(3)
Neurochemical research 2026 Apr 27;51(3)
KDM2B-PP1 Promotes Remyelination and Functional Recovery After Facial Nerve Injury.
Xu H, Yang H, Cao Y, Fan Z
Journal of oral rehabilitation 2026 Apr 24;
Journal of oral rehabilitation 2026 Apr 24;
Gypenosides ameliorate depression by modulating microglial state transition via the NLRP3/Caspase-1/ASC signaling pathway.
Guo M, Cui C, Zheng ZJ, Li N, Yuan HS, Chen YH, Ding H, Zhang Y, Cheng Y, Piao XL
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr 15;156:158189
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr 15;156:158189
Sleep deprivation accelerates Parkinson's disease pathology by upregulating LAG3 in astrocytes and disrupting glymphatic system function.
Sun YR, Lv QK, Xue XY, Zhang Y, Shi LY, Sun ML, Shen Y, Mao CJ, Wang LH, Wang F, Liu JY, Liu CF
Journal of advanced research 2026 Apr 13;
Journal of advanced research 2026 Apr 13;
Thalamic glutamatergic neurons regulate seizure onset and generalization in temporal lobe epilepsy.
Liang S, Han Y, Wang J, Liu L, Zhu M, Zhang M, Sun Z, Zhang X, Wang Y, Sun Y
Cell reports 2026 Apr 10;45(4):117246
Cell reports 2026 Apr 10;45(4):117246
Injectable Brain Extracellular Matrix Hydrogels Enhance Neuronal Migration and Functional Recovery After Intracerebral Hemorrhage.
Xia J, Gao X, Yao J, Fei Y, Song D, Gu Z, Zheng G, Gu Y, Tu C
Biomaterials research 2025;29:0192
Biomaterials research 2025;29:0192
Curcumin-enhanced elvitegravir therapy mitigates neuroinflammation and cognitive deficits in EcoHIV mice.
Godse S, Zhou L, Sinha N, Salman M, Ishrat T, Kumar S
Experimental biology and medicine (Maywood, N.J.) 2025;250:10758
Experimental biology and medicine (Maywood, N.J.) 2025;250:10758
Comparisons of the Effects of Low- or High-Fat Diets Rich in Soybean Oil, Lard, and Tea Seed Oil on Markers of Blood-Brain Barrier and Neuroinflammation in Ovariectomized Mice.
Lin SH, Soetanto CG, Chiu WC, Cross TL, Kao NJ, Wu YR, Lin CI, Jha P
International journal of food science 2025;2025:4154633
International journal of food science 2025;2025:4154633
Co-regulation of microglial subgroups in Alzheimer's amyloid pathology: Implications for diagnosis and drug development.
Zhou Y, Huang Y, Fan Y, Xue F
PloS one 2025;20(12):e0337741
PloS one 2025;20(12):e0337741
Astrocytic Ror2-induced imbalance in brain and gut homeostasis contributes to chronic post-thoracotomy pain.
Liu C, Shen L, Xu L, Zhu A, Huang Y
Frontiers in aging neuroscience 2025;17:1675725
Frontiers in aging neuroscience 2025;17:1675725
Optineurin overexpression ameliorates neurodegeneration through regulating neuroinflammation and mitochondrial quality in a murine model of amyotrophic lateral sclerosis.
Zhao S, Chen R, An Y, Zhang Y, Ma C, Gao Y, Lu Y, Yang F, Bai X, Zhang J
Frontiers in aging neuroscience 2025;17:1522073
Frontiers in aging neuroscience 2025;17:1522073
Baicalein ameliorates cognitive decline induced by chronic cerebral hypoperfusion through the SIRT1-mediated Notch1 pathway to improve angiogenesis and suppress neuroinflammation.
Li M, Song J, Niu X, Mo F, Xie X, Li X, Yin Y, Wang T, Song X, Liu J, Lv P
Frontiers in aging neuroscience 2025;17:1521353
Frontiers in aging neuroscience 2025;17:1521353
Polyphenol-rich Morus nigra L. extract mitigates neuroinflammation and cognitive impairment through gut-brain axis modulation in an Alzheimer's disease rat model.
Li Y, Zhang Y, Liu M, Dawuti T, Chen X, Xiao H
Frontiers in pharmacology 2025;16:1695768
Frontiers in pharmacology 2025;16:1695768
The protective effect of Blautia coccoides in secondary injury of intracerebral hemorrhage.
Shao X, Zheng M, Ye C, Lu J, Li M, Su K, Lin H, He L, Qi X, Wang J
Frontiers in microbiology 2025;16:1616222
Frontiers in microbiology 2025;16:1616222
Integrated proteomics analysis and network pharmacology to elucidate the mechanism of Zhilong Huoxue Tongyu Capsule alleviate hypertensive retinopathy in Ang II infusion mice model.
Wu J, Xie W, Xie Y, Mazhar M, Duan J
Frontiers in pharmacology 2025;16:1573693
Frontiers in pharmacology 2025;16:1573693
Biomimetic piezoelectric hydrogel system for energy metabolism reprogramming in spinal cord injury repair.
Shi G, Su T, Li J, Wang A, Gao G, Tao B, Chen N, Tian L, Yan J, Zhao L, Zhang J, Zhao Y
Theranostics 2025;15(11):4955-4969
Theranostics 2025;15(11):4955-4969
Mechanistic insights into the anti-depressant effect of quercetin: an integrated bibliometrics, bioinformatics, and animal experimentation.
Song Z, Wu Y, Luo L, Hu Q, Wu S, Wu M, Zhang G
Frontiers in nutrition 2025;12:1612746
Frontiers in nutrition 2025;12:1612746
The effect of ponicidin on CFA-induced chronic inflammatory pain and its mechanism based on network pharmacology and molecular docking.
Wang P, Jiang H, Yao J, He G, Tao T, Qin Z
Frontiers in medicine 2025;12:1510271
Frontiers in medicine 2025;12:1510271
miR-17-5p Regulates Astrocyte Activation Through Targeting Mfn2 to Improve Nerve Function in Rats With Spinal Cord Injury.
Zhao Y, Wu H, Xu M, Zhong Y
The European journal of neuroscience 2025 Sep;62(6):e70257
The European journal of neuroscience 2025 Sep;62(6):e70257
Phase-adapted metal ion supply for spinal cord repair with a Mg-Zn incorporated chimeric microsphere.
Liu X, Ma B, Hu S, Li D, Pan C, Xu Z, Chen H, Wang Y, Wang H
Biomaterials 2025 Sep;320:123253
Biomaterials 2025 Sep;320:123253
Novel "hot spring"-mimetic scaffolds for sequential neurovascular network reconstruction and osteoporosis reversion.
Zhao Y, Liu J, Hu L, Yao X, Tu R, Goto T, Zhang L, Wu X, Liu G, Dai H
Biomaterials 2025 Sep;320:123191
Biomaterials 2025 Sep;320:123191
RNA-binding proteins mediate the maturation of chromatin topology during differentiation.
Dehingia B, Milewska-Puchała M, Janowski M, Rafiee MR, Abbas M, Piotrowska A, Senge J, Blaut P, Walsh D, Severino J, Chaudhury D, Iqbal S, Montiel-Manriquez R, Jankowska S, Zare P, Huber W, Xu J, Casellas R, Zimmermann T, Dłotko P, Krijgsveld J, Pękowska A
Nature cell biology 2025 Sep;27(9):1510-1525
Nature cell biology 2025 Sep;27(9):1510-1525
Madecassoside exerts anti-neurodegeneration effects in protein l-isoaspartyl methyltransferase deficient mice via targeting PRDX2-mediated oxidative stress and inflammation.
Zhong W, Zhu G, Lu D, Wang L, Zhang B, Su Z, Qin Z
Biochemical pharmacology 2025 Sep;239:117034
Biochemical pharmacology 2025 Sep;239:117034
Lysophosphatidic acid receptor 5 in insular cortex as a potential analgesic target in neuropathic pain.
Wang B, Feng X, Woodhouse K, Sharma D, Meng X, Shang H, Hu H, Zhang D, Zhang Y, Li JX, Tao YX
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2025 Sep;22(5):e00609
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2025 Sep;22(5):e00609
Nitration of Tyrosine Residue Y10 of Aβ(1-42) Ameliorates Aβ(1-42)-Induced Neurotoxicity and Memory Impairment In Vitro and In Vivo.
Zhao J, Chen J, Lu J, Shi Q, Wang Q, Gao Z, Zeng L, Liu Q
Journal of neurochemistry 2025 Sep;169(9):e70218
Journal of neurochemistry 2025 Sep;169(9):e70218
Irisin/FNDC5 Regulates Endothelial Function to Improve Post-Stroke-Induced Cognitive Dysfunction by Stimulating AMPK-eNOS Signaling.
Guo HH, Liang JJ, Pan RH, Zheng MF, Qiu YX, Jiang SS, Fu XY, Tsang HW, Yau SY, Ou HN
Brain and behavior 2025 Sep;15(9):e70767
Brain and behavior 2025 Sep;15(9):e70767
A Myelin Debris Cleaner for Spinal Cord Injury Recovery: Polycaprolactone / Cell Membrane Assembled Scaffolds.
Zhou Y, Xu T, Zhou Y, Chen N, Wu Z, Yang Z, Yang C, Chen X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(36):e03269
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(36):e03269
Isoacteoside alleviates LPS-induced depressive-like behaviors in mice by inhibiting neuroinflammation through regulating microglial polarization and oxidative stress.
Bi J, Zhang H, Wei J, Huang X, Dong Y, Dong Y, Xie Y, Li R, Chen S, Zhao Z, Cheng B
Behavioral and brain functions : BBF 2025 Sep 29;21(1):30
Behavioral and brain functions : BBF 2025 Sep 29;21(1):30
MSCs-EXOs containing miR-21a-5p promoted cell proliferation in the rat retinal Müller cell rMC-1 via targeting LATS1.
Deng L, Wang Y
Stem cell research & therapy 2025 Sep 29;16(1):529
Stem cell research & therapy 2025 Sep 29;16(1):529
Neurotoxicity, α-synuclein pathology, and mitochondrial dysfunction: A comparative study of different mouse models of Parkinson's disease.
Tang X, He Y, Liang M, Ning P, Zhao J, Zhang Y, Yan X, Sun R, Wei G, Shen R, Huang F, Yu M
Neural regeneration research 2025 Sep 29;
Neural regeneration research 2025 Sep 29;
Transcription factor RUNX2 participates in astrocyte-mediated neuropathic pain via transcriptional activation of Ccl2.
Shen W, Song S, Zhao X, Li D, Liu J, Yue S
Biochemical and biophysical research communications 2025 Sep 1;777:152263
Biochemical and biophysical research communications 2025 Sep 1;777:152263
Transplanting neural stem cells overexpressing miRNA-21 can promote neural recovery after cerebral hemorrhage through the SOX2/LIN28-let-7 signaling pathway.
Dai W, Li Y, Du J, Shen G, Fan M, Su Z, Xu F, Yuan F
Animal models and experimental medicine 2025 Oct;8(10):1760-1774
Animal models and experimental medicine 2025 Oct;8(10):1760-1774
Hypoxia preconditioned MSC exosomes attenuate high-altitude cerebral edema via the miR-125a-5p/RTEF-1 axis to protect vascular endothelial cells.
Zuo JC, Liang J, Hu N, Yao B, Zhang QJ, Zeng XL, Zhang LJ, Zhang X, Chang ZH, Chen C, Yan XJ, Shao WW, Zhu P, Li XH
Bioactive materials 2025 Oct;52:541-563
Bioactive materials 2025 Oct;52:541-563
Tailoring the therapeutic potential of stem cell spheroid-derived decellularized ECM through post-decellularization BDNF incorporation to enhance brain repair.
Kao YC, Yang PC, Lin YP, Chen GH, Liu SW, Ho CH, Huang SC, Lee PY, Chen L, Huang CC
Biomaterials 2025 Oct;321:123332
Biomaterials 2025 Oct;321:123332
GSDME-dependent astrocyte pyroptosis promotes the progression of neuroinflammation in experimental cerebral malaria.
Wang J, Zhu Q, Tong G, Yu K, Liang J, Huang Y, Wang Y, Yang C, Li T, Liang W, Li G, Liu X, Sun J, Li Y, Shen Y, Zhao Y
Apoptosis : an international journal on programmed cell death 2025 Oct;30(9-10):2385-2400
Apoptosis : an international journal on programmed cell death 2025 Oct;30(9-10):2385-2400
TSP50 in Neural Stem Cells Regulates Aging-Related Cognitive Decline and Neuroinflammation by Altering the Gut Microbiota.
Li X, Chen Y, Gao Z, Liu X, Song Z, Gao F, Wang S, Yu C, Sun L, Huang Y, Zheng L, Wang G, Sun Y, Li J, Yang X, Bao Y
Aging cell 2025 Oct;24(10):e70188
Aging cell 2025 Oct;24(10):e70188
TRPC6 suppresses liver fibrosis by inhibiting hepatic stellate cell activation via CaMK4-CREB pathway.
Jiang S, Wang Y, Ren Y, Tang Q, Xue C, Wang Z, Zhang Q, Hu Y, Wang H, Zhao F, Zhu MX, Cao Z
British journal of pharmacology 2025 Oct;182(20):5004-5022
British journal of pharmacology 2025 Oct;182(20):5004-5022
PPARα-Mediated Fatty Acid Catabolism in Astrocytes Was Involved in Improvement of Cognitive Dysfunction by Phlorizin in APP/PS1 Mice.
Fu Y, Zhang X, Li L, Jiang H, Ren Q, Yi T, Zhang Y, Lu Y
Antioxidants (Basel, Switzerland) 2025 Oct 31;14(11)
Antioxidants (Basel, Switzerland) 2025 Oct 31;14(11)
Cerebrospinal fluid extracellular vesicle-derived miR-9-3p in spinal cord injury with neuroprotective implications and biomarker development.
Tanaka T, Morimoto S, Ito K, Yasutake K, Kato C, Shinozaki M, Suda K, Maeda T, Yato Y, Nakamura M, Okano H, Nagoshi N
Communications biology 2025 Oct 27;8(1):1498
Communications biology 2025 Oct 27;8(1):1498
CMTM6 drives glioblastoma progression by promoting M2 polarization and suppressing antigen presentation in microglia/macrophages.
Li X, Han W, Cai W, Yang R, Bai G, Sun C, Ge S, Zhang C, Han X, Yang H, Chen Y, Shan Q, Li X, Tian X, Lyu Y, Li J, Wang X
European journal of medical research 2025 Oct 27;30(1):1018
European journal of medical research 2025 Oct 27;30(1):1018
Non-Competitive AMPA Receptor Antagonist Perampanel Inhibits Ischemia-Induced Neurodegeneration and Behavioral Deficits in Focal Cortical Pial Vessel Disruption Stroke Model.
Zaki MG, Moutaoufik MT, Pordeli M, Babu M, Taghibiglou C, Cayabyab FS
Cells 2025 Oct 19;14(20)
Cells 2025 Oct 19;14(20)
Ursolic acid improves cognitive impairment in type 2 diabetic mice by preventing complement 3 secretion and neuropathy.
Suo Y, Fu Y, Wang C, Wu Y, Tian P
Brain research bulletin 2025 Oct 15;231:111562
Brain research bulletin 2025 Oct 15;231:111562
Enriched environment ameliorates neurobehavioral abnormalities, hippocampal inflammation, and synaptic dysfunction in adult male mice exposed to intermittent hypoxia during pregnancy.
Fang SK, Hu F, Zhang Y, Lun WZ, Zhang YM, Li XY, Zhang KX, Hu ZY, Wei RM, Ren CY, Chen GH
Brain research bulletin 2025 Oct 15;231:111544
Brain research bulletin 2025 Oct 15;231:111544
Exosome derived from bone marrow derived mesenchymal stem cells prevents LPS-induced depressive like behaviors.
Liu H, Yan XJ, Hu JL, Pan H, Mao X, Cheng Y
Brain research bulletin 2025 Oct 15;231:111527
Brain research bulletin 2025 Oct 15;231:111527
Lactylation-induced ALKBH5 targets RNF123 to worsen retinal Müller cell activation through PKM2-regulated Glycolysis in diabetic retinopathy.
Luo S, Sun Y, Hu Y, Xu Y
Journal of translational medicine 2025 Oct 15;23(1):1105
Journal of translational medicine 2025 Oct 15;23(1):1105
Mechanism of retinal angiogenesis induced by HIF-1α and HIF-2α under hyperoxic conditions.
Feng X, Li C, Zhang W, Jiao K, Zhang L, Xiao L
Scientific reports 2025 Oct 15;15(1):36049
Scientific reports 2025 Oct 15;15(1):36049
Innate immune sensing of Z-nucleic acids by ZBP1-RIPK1 axis drives neuroinflammation in Alzheimer's disease.
Song Z, Xie X, Chen Y, Zhang B, Li X, Yang Y, Mo W, Zhang J, Xu D
Immunity 2025 Oct 14;58(10):2574-2592.e9
Immunity 2025 Oct 14;58(10):2574-2592.e9
Disulfide-Appended siRNA Nanoeyedrops: Noninvasive Gene Therapy for Targeting Retinal Angiogenesis.
Liu S, Wang D, Ye S, Zhang J, Du B, Lian Z, Yang W, Zhou J, Chen Q, Li J, Li J, Yang H
ACS nano 2025 Oct 14;19(40):35333-35347
ACS nano 2025 Oct 14;19(40):35333-35347
Comprehensive profiling of transcription factors for reprogramming human astrocytes to neuronal cells through endogenous CRISPR-based gene activation.
Reisman SJ, Halabi D, Miller SE, Song L, Geraghty S, Sangvai N, Rice G, Safi A, Crawford GE, Gersbach CA
bioRxiv : the preprint server for biology 2025 Oct 12;
bioRxiv : the preprint server for biology 2025 Oct 12;
Engineered extracellular vesicles for targeted FGF20 delivery enhance neuroplasticity and functional recovery in ischemic stroke.
Guo S, Wang Z, Shi R, Huang P, Fang Y, Chen S, Huang M, Hu J, Lu Y, Xu X, Zou Y, Ruan L, Li X, Lin L, Wang X
Journal of controlled release : official journal of the Controlled Release Society 2025 Oct 10;386:114080
Journal of controlled release : official journal of the Controlled Release Society 2025 Oct 10;386:114080
Picroside II Alleviates the Progression of Alzheimer's Disease via the NLRP3/Caspase-1/GSDMD Pathway.
Li S, Gao Y, Zhang Y, Zhang J, Zhao Y, Chang C, Gao X, Zhang J, Yang G
Neuromolecular medicine 2025 Oct 10;27(1):68
Neuromolecular medicine 2025 Oct 10;27(1):68
Identification of disease-associated molecular signatures in the Prp-TDP-43A315T mouse model of ALS: Toward preclinical biomarker development.
Al Ojaimi Y, Osman S, Alarcan H, Emond P, Veyrat-Durebex C, Lanznaster D, Meme S, Clemencon R, Galineau L, Corcia P, Andres C, Vourc'h P, Masse F, Trovero F, Blasco H
Journal of neuropathology and experimental neurology 2025 Oct 1;84(10):911-927
Journal of neuropathology and experimental neurology 2025 Oct 1;84(10):911-927
Isocucurbitacin B inhibits gliomas through the promotion of anoikis by targeting caveolin 1.
Han M, Yang J, Chen P, Li S, Tang H, Fan H, Wang Y, Li X, Pan W, Koutouratsas V, Zhao Z, Peng F
Cancer letters 2025 Oct 1;629:217873
Cancer letters 2025 Oct 1;629:217873
CircFGFR2 induces astrocyte pyroptosis to promote ischemic stroke.
Pang N, Liu Y, Yu S, Li Y, Shi K
Neuroscience 2025 Oct 1;584:356-366
Neuroscience 2025 Oct 1;584:356-366
Long noncoding RNA NONRATT007487.2 drives cancer-induced bone pain progression through direct interaction with CXCL1.
Jiang H, Wang L, Xu Y, Dai Z, Chen J, Zheng D, Zheng H
The Korean journal of pain 2025 Oct 1;38(4):378-390
The Korean journal of pain 2025 Oct 1;38(4):378-390
NPB-1575 attenuates neuroinflammation and resists ferroptosis in rat ischemic stroke via IRS2 signaling pathway.
Li XN, Shang NY, Liu MY, Sui SY, Tang JS, Lan JQ, Kang YY, Zhang BD, Wen ZP, Feng XH, Wu L, Dai JG, Peng Y
Acta pharmacologica Sinica 2025 Nov;46(11):2893-2907
Acta pharmacologica Sinica 2025 Nov;46(11):2893-2907
Artemisinin Alleviates Chronic Social Defeat Stress-Induced Depressive-Like Behavior by Inhibiting Neuroinflammation via the TLR4/MyD88/NF-κB/NLRP3 Signaling Pathway.
Wang L, Li H, Zhao Y, Sun X, Qian M, Shao F, Li L, Hu W, Dai L, Bao H
Phytotherapy research : PTR 2025 Nov;39(11):5263-5281
Phytotherapy research : PTR 2025 Nov;39(11):5263-5281
Icariside II Ameliorates Depression Induced by High-Fat Diet via the Microbiota-Gut-Brain Axis in Mice.
Luo YM, Dong L, Li YL, Lin M, Xie DY, Gao JM, Zhang YD, Zhu YZ, Gong QH
Phytotherapy research : PTR 2025 Nov;39(11):5159-5173
Phytotherapy research : PTR 2025 Nov;39(11):5159-5173
Flexible Living Artificial Dura Mater for Efficient Therapy of Central Nervous System Injury Based on Neuronal Differentiation and Neuroprotective A2 Astrocyte Activation.
Yang H, Liu H, Lou C, Han M, Sun Z, Su Y, Bian K, Zhao D, Li Y, Sang Y, Liu C, Geng Z, Liu H, Qiu J
Advanced materials (Deerfield Beach, Fla.) 2025 Nov;37(45):e11878
Advanced materials (Deerfield Beach, Fla.) 2025 Nov;37(45):e11878
Astrocyte-microglia crosstalk in the hippocampus mediates cognitive impairments induced by chronic intermittent hypoxia.
Wu ZH, Zhai MR, Wang YR, Ren L, Pan J, Xiao L, Liu YH
Neurobiology of disease 2025 Nov;216:107117
Neurobiology of disease 2025 Nov;216:107117
Neuronutritional enhancement of antioxidant defense system through Nrf2/HO1/NQO1 axis in fibromyalgia.
Inferrera F, Tranchida N, Fusco R, Cuzzocrea S, Impellizzeri D, Siracusa R, D'Amico R, Rashan L, Badaeva A, Danilov A, Calabrese V, Di Paola R, Cordaro M
Neurochemistry international 2025 Nov;190:106057
Neurochemistry international 2025 Nov;190:106057
Combination therapy with 3-Hydroxybenzaldehyde and Albendazole modulates mitochondrial protein expression in astrocytes after Angiostrongylus cantonensis infection.
Huang YH, Chang SH, Cheng CJ, Lin YH, Chou YC, Chen CL, Chen KY
PLoS neglected tropical diseases 2025 Nov;19(11):e0013773
PLoS neglected tropical diseases 2025 Nov;19(11):e0013773
Scorpion venom heat-resistant synthetic peptide improves cognitive dysfunction of APP/PS1 mice through microglial retromer complex.
Zhang Y, Wu YX, Zhang XG, Guo SY, He J, Hu NN, Huang YL, Kong Y, Li QF, Sui AR, Zhu BH, Piao H, Zhao J, Li S
British journal of pharmacology 2025 Nov;182(21):5391-5408
British journal of pharmacology 2025 Nov;182(21):5391-5408
METTL3 modulates bone Cancer pain via m(6)A-dependent JAK2/STAT3 activation in spinal astrocytes.
Liu M, Yang L, Yan Z, Huang Y
Cellular signalling 2025 Nov;135:112046
Cellular signalling 2025 Nov;135:112046
Chronic psychological stress-orchestrated glial-ILC3 circuit exacerbates intestinal inflammation and depression.
Zhang Z, Ren S, Fan X, Chen H, Chen J, Wang X, Zong H, Zhang S, Zhao T, Sun Y, Pang R, Song W, Zhang W, Wang B, Chen Z, Ge L
Brain, behavior, and immunity 2025 Nov;130:106118
Brain, behavior, and immunity 2025 Nov;130:106118
Ketone monoester alleviates cognitive impairment in a transgenic mouse model of Alzheimer's disease through innate immunological IFITM3 pathway.
Zhang T, Ruan J, Liu Z, Yu Y, Lu Y, Zhang X, Hou C, Liu X, Yuan Y, Han X
Brain, behavior, and immunity 2025 Nov;130:106094
Brain, behavior, and immunity 2025 Nov;130:106094
Parylation dependent nuclear export of HMGB1 via exportin 1 contributes to morphine tolerance.
Liang YP, Zhang DY, Le DS, Liu L, Yang F, Sun SY, Lai GR, Zhang C, Zhao ML, Liao PS, Liu T, Wang B
Brain, behavior, and immunity 2025 Nov;130:106070
Brain, behavior, and immunity 2025 Nov;130:106070
The GLP1R Agonist Semaglutide Inhibits Reactive Astrocytes and Enhances the Efficacy of Neural Stem Cell Transplantation Therapy in Parkinson's Disease Mice.
Song D, Zou X, Ma D, Zhao Y, Liu T, Shen B, Cheng O
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(43):e17664
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(43):e17664
Hepatic acetyl-CoA metabolism modulates neuroinflammation and depression susceptibility via acetate.
Cao Y, Zhao Y, Deng T, Zhou Q, Hu G, Hu ZL, Jiang YY, Yang XH, Wang F, Wu PF, Chen JG
Cell metabolism 2025 Nov 4;37(11):2185-2201.e8
Cell metabolism 2025 Nov 4;37(11):2185-2201.e8
Microglial activation drives neuronal dysregulation in alcohol-induced seizure susceptibility.
Zhang S, Zhou Y, Ren Y, Shang J, Jiang A, Hong Y, Hong S, Wang C, Wang W, Chen J
Scientific reports 2025 Nov 3;15(1):38389
Scientific reports 2025 Nov 3;15(1):38389
Parthenolide Exerts Protection against Hypoxic-Ischemic Brain Damage in Neonatal Rats by Inhibiting Perk-Mediated Endoplasmic Reticulum Stress.
Mao N, Zheng Y, Yuan J, Feng X, Ren Y, Wang X, Tao X, Wang X, Fang M, Lin Z
Molecular neurobiology 2025 Nov 29;63(1):210
Molecular neurobiology 2025 Nov 29;63(1):210
Zexieyin formula attenuates Alzheimer's disease via suppressing A1 astrocyte activation: A serum pharmacochemistry and network pharmacology study.
Zhou S, Sun M, Song Z, Qin Z, Wu H, Wang M, Zhu B
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157375
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157375
Urolithin B promotes the functional recovery of spinal cord injury by alleviating neuroinflammation via the inhibition of NLRP3 signaling pathway.
Su Y, Wang H, Yang W, Zhang S, Liu F, Han K, Guan F, Ma S, Cui Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157331
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157331
Presence of Astrocytic S1R/5-HT1A Heterocomplex in the mPFC: A Putative Link to S1R Activation Mediated Faster Antidepressant-Like Effects.
Ren P, Wang JY, Xu MJ, Ni H, Zhang S, Yue CX, Yang DY, Li YF
Molecular neurobiology 2025 Nov 24;63(1):163
Molecular neurobiology 2025 Nov 24;63(1):163
Glial cells missing 1 triggers gliosis and angiogenesis after neonatal brain injury.
Hayashi Y, Abdullah A, Fuke S, Fazera Mohd Ariffin NA, Daun KA, Morimura N, Nakabayashi K, Tatsumoto S, Go Y, Hosoya T, Hitoshi S
iScience 2025 Nov 21;28(11):113860
iScience 2025 Nov 21;28(11):113860
Neutralizing XCL1 Attenuates Brain Injury and Reduces Lymphocyte and Dendritic Cell Recruitment Following Intracerebral Hemorrhage in Mice.
Shi J, Chen S, Wang J, Rastegar-Kashkooli Y, Fu P, Huang M, Zhang J, Wang J, Jiang C
Molecular neurobiology 2025 Nov 19;63(1):70
Molecular neurobiology 2025 Nov 19;63(1):70
Umbilical Cord Mesenchymal Stromal Cell-Derived Extracellular Vesicles Transfer CD59 to Astrocytes to Alleviate Complement-Dependent Cytotoxicity.
Shen Q, Wang X, Ou Q, Wang Q, Zhao Z, Chen Z, Zhu X, Li D, Jin C, Gao F, Wang J, Lu L, Bi Y, Wan W, Guan Y, Xu GT, Xu JY, Tian H
Molecular neurobiology 2025 Nov 14;63(1):41
Molecular neurobiology 2025 Nov 14;63(1):41
Inhibition of Neuroinflammation by Costunolide Attenuates Hypoxic-Ischemic Brain Damage via the PI3K/AKT Pathway in Neonatal Rats.
Hu Y, Qian R, He Y, Gao Q, Wang X, Lin H, Lin W, Fang Y, Zhu J, Wang X, Nan Y, Lin Z
Molecular neurobiology 2025 Nov 14;63(1):39
Molecular neurobiology 2025 Nov 14;63(1):39
Osthole alleviates neuropathic pain by suppressing astrocytes activation and associated inflammatory responses via the PKCδ/TRPV4 signaling pathway.
Xu X, Song S, Zhao X, Qu Y, Li D, Shen L, Liu J, Yue S
International immunopharmacology 2025 Nov 14;165:115453
International immunopharmacology 2025 Nov 14;165:115453
Wuling San ameliorates cerebral ischemia-reperfusion injury via suppression of the TRPM2/NLRP3 pathway.
Li H, Tao D, Chen Y, Deng Y, Wei W, Xue X
European journal of medical research 2025 Nov 10;30(1):1096
European journal of medical research 2025 Nov 10;30(1):1096
NR2A-Wnt-TLR2 signaling axis mediates neuronal mitochondrial dysfunction contributing to neuropathic pain induced by nerve injury in diabetic mice.
Zhang YY, Wang MY, Zhu DX, Li YL, Yi YT, Zhou C, Li CJ, Liu F, Shen JF
Neuropharmacology 2025 Nov 1;278:110561
Neuropharmacology 2025 Nov 1;278:110561
The compound (E)-2-(3,4-dihydroxystyryl)-3-hydroxy-4H-pyran-4-one alleviates neuroinflammation and cognitive impairment in a mouse model of Alzheimer's disease.
Liu X, Wu W, Li X, Wang C, Chai K, Yuan F, Zheng H, Yao Y, Li C, Ye ZC, Zha D
Neural regeneration research 2025 Nov 1;20(11):3330-3344
Neural regeneration research 2025 Nov 1;20(11):3330-3344
Single-Cell RNA Sequencing Uncovers Molecular Features Underlying the Disrupted Neurogenesis Following Traumatic Brain Injury.
Liu C, Shao FH, He XC, Du HZ, Liu CM, Zhou B, Teng ZQ
Glia 2025 May;73(5):1036-1050
Glia 2025 May;73(5):1036-1050
Characterization of Dystrophin Dp71 Expression and Interaction Partners in Embryonic Brain Development: Implications for Duchenne/Becker Muscular Dystrophy.
Fujimoto T, Mori M, Tonosaki M, Yaoi T, Nakano K, Okamura T, Itoh K
Molecular neurobiology 2025 May;62(5):6256-6272
Molecular neurobiology 2025 May;62(5):6256-6272
Radiation Damage to a Three-Dimensional Hydrogel Model of the Brain Perivascular Niche.
Ivanova YI, Nunes AC, Cruz V, Selting K, Harley BAC
Tissue engineering. Part C, Methods 2025 May;31(5):181-190
Tissue engineering. Part C, Methods 2025 May;31(5):181-190
Genetic mutation in HSF4 is associated with retinal degeneration in mice.
Liu B, Lang Y, Li Y, Jiang M, Xue M, Jia X, Peng X, Hu Y
Experimental eye research 2025 May;254:110316
Experimental eye research 2025 May;254:110316
Astragalin actives autophagy and inhibits apoptosis of astrocytes in AD mice via down-regulating Fas/Fasl-VDAC1 pathway.
Wang S, Yang Y, Lin J, Zhang W, Yang C, Zhang R, Zhou C, Zhang L, Wang X, Liu J, Jin X, Ma Y
Free radical biology & medicine 2025 May;232:72-85
Free radical biology & medicine 2025 May;232:72-85
Astragalin alleviates lipopolysaccharide-induced depressive-like behavior in mice by preserving blood-brain barrier integrity and suppressing neuroinflammation.
Cao MM, Guo Z, Wang J, Ma HY, Qin XY, Hu Y, Lan R
Free radical biology & medicine 2025 May;232:340-352
Free radical biology & medicine 2025 May;232:340-352
Berbamine alleviates neuropathic pain via suppressing spinal TMEM34/SGK1/FOXO3 axis.
Yao CH, Zhang ZM, Zhang S, Jiang H, Wang R, Liu JH, Xie H, Dai WL
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 May;140:156619
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 May;140:156619
RACK7 Interacts with PRC2 Complex to Regulate Astrocyte Development.
Jiao F, Tang T, Wang B, He S, Zhang Y, Dong L, Xu B, Liu Y, Zhu P, Guo R
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 May;12(19):e2416350
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 May;12(19):e2416350
NSAID-mediated cyclooxygenase inhibition disrupts ectodermal derivative formation in axolotl embryos.
Marshall EJ, Ramarapu R, Leathers TA, Morrison-Welch N, Sandberg K, Kawashima M, Rogers CD
Differentiation; research in biological diversity 2025 May-Jun;143:100856
Differentiation; research in biological diversity 2025 May-Jun;143:100856
Poliumoside Exhibits Neuroprotective Effects against Cerebral Ischemia-Reperfusion Injury by Relieving Microglia-Mediated Neuronal Damage and Astrocytic Activation.
Bai L, Guan Z, Zhang J, Lv Z, Duan Y, Tian S
ACS chemical neuroscience 2025 May 7;16(9):1780-1791
ACS chemical neuroscience 2025 May 7;16(9):1780-1791
Neutrophil Extracellular Traps Promote AIM2-Dependent Microglial Pyroptosis Following Stroke.
Chen H, Ni L, Zhang J, Zheng X, Chen Y, Jin X, Hu B, Xu X, Tang Q, Li S, Hao Y, Sun S, He C, Cao S, Hu X
Aging and disease 2025 May 30;17(3):1616-1633
Aging and disease 2025 May 30;17(3):1616-1633
Neuronal Deletion of Tumor Susceptibility Gene 101 (Tsg101) Causes Rapid Apoptotic Loss of Hippocampal CA3 Neurons.
Walker WP, Ratz-Mitchem ML, Wagner KU, Gunn TM
Biomolecules 2025 May 28;15(6)
Biomolecules 2025 May 28;15(6)
Galectin-3 activates microglia and promotes neurological impairment via NLRP3/pyroptosis pathway following traumatic brain injury.
Sun Y, Gao SQ, Wang X, Li T, Han YL, Miao SH, Zhao R, Zheng XB, Qiu JY, Jin WX, Gao CC, Zhou ML
Brain research 2025 May 15;1855:149560
Brain research 2025 May 15;1855:149560
Chemotactic Zn micromotor for treatment of high blood ammonia-associated hepatic encephalopathy.
Feng Y, Gao C, Peng X, Chen B, Ding M, Du D, Rong J, Lv Q, Wilson DA, Tu Y, Peng F
Nature communications 2025 May 15;16(1):4525
Nature communications 2025 May 15;16(1):4525
Parvalbumin neurons mediate neurological phenotypes of anti-NMDAR encephalitis.
Feng YF, Zeng ZK, Ni Y, Hu Y, Yang KX, Cai F, Zhou QM, Chen M, Zhu XN, Chen S, Hu J
Brain : a journal of neurology 2025 May 13;148(5):1652-1664
Brain : a journal of neurology 2025 May 13;148(5):1652-1664
Elucidation of Dexmedetomidine-Induced Analgesic Tolerance Mechanisms in Neuropathic Pain With Modulation of SGK1, NR2A, and NR2B Expression via the Spinal SGK1/NF-κB Signalling Pathway.
Huikang W, Shiya C, Di P, Kiani FA, Hao L, Sha N, Xuan L, Abouelfetouh MM, Ahmed Z, Mingxing D, Yi D
Journal of cellular and molecular medicine 2025 Mar;29(6):e70372
Journal of cellular and molecular medicine 2025 Mar;29(6):e70372
Evaluation of cytoprotective effects of cannabidiol on neuroinflammation and neurogenesis process in rat offsprings.
Catakli D, Erzurumlu Y, Asci H, Savran M, Sezer S
Reproductive toxicology (Elmsford, N.Y.) 2025 Mar;132:108761
Reproductive toxicology (Elmsford, N.Y.) 2025 Mar;132:108761
Egln3 expression in microglia enhances the neuroinflammatory responses in Alzheimer's disease.
Guan J, Wu P, Liu M, Jiang C, Meng X, Wu X, Lu M, Fan Y, Gan L
Brain, behavior, and immunity 2025 Mar;125:21-32
Brain, behavior, and immunity 2025 Mar;125:21-32
MicroRNA-204-5p Deficiency within the vmPFC Region Contributes to Neuroinflammation and Behavioral Disorders via the JAK2/STAT3 Signaling Pathway in Rats.
Chen X, Gan Y, Zhang K, Wu Y, Li Y, Lan T, Zhuang X, Chen S, Yu S
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Mar;12(10):e2403080
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Mar;12(10):e2403080
Indole-3-Propionic Acid Attenuates Neuroinflammation and Cognitive Deficits by Inhibiting the RAGE-JAK2-STAT3 Signaling Pathway.
Hao Z, Ji R, Su Y, Wang H, Yang W, Zhang S, Liu Y, Ma S, Guan F, Cui Y
Journal of agricultural and food chemistry 2025 Mar 5;73(9):5208-5222
Journal of agricultural and food chemistry 2025 Mar 5;73(9):5208-5222
Proteomic Profiling and Therapeutic Targeting of Oxidative Stress in Autoimmune Encephalitis.
Zhang F, Zhang C, Sun W, Xie S, Wu P, Zeng G, Liu X
Journal of molecular neuroscience : MN 2025 Mar 19;75(2):38
Journal of molecular neuroscience : MN 2025 Mar 19;75(2):38
Reprogramming of skin fibroblasts by 3D spheroid culture promotes peripheral nerve regeneration via the ID3/semaphorin7a pathway.
Tan X, Zhang Z, Cao X, Qu L, Xiong Y, Li H, Wang Y, Chen Z, Shi C
Stem cells translational medicine 2025 Mar 18;14(3)
Stem cells translational medicine 2025 Mar 18;14(3)
Role of FPR2 antagonism in alleviating social isolation-induced depression and protecting blood-brain barrier integrity.
Zheng J, Wang H, Wu W, Wang L, Qin M, Zhu L, Liu Z, Chen Y, Yu Y
Journal of neuroinflammation 2025 Mar 13;22(1):79
Journal of neuroinflammation 2025 Mar 13;22(1):79
Arsenic exposure induces neural cells senescence and abnormal lipid droplet accumulation leading to social memory impairment in mice.
Zhang B, Chen J, Wang J, Pan X
Environmental pollution (Barking, Essex : 1987) 2025 Mar 1;368:125779
Environmental pollution (Barking, Essex : 1987) 2025 Mar 1;368:125779
Activation of NR2A-Wnt-TLR2 Signaling Axis in Satellite Glial Cells of the Dorsal Root Ganglion Contributes to Neuropathic Pain Induced by Nerve Injury in Diabetic Mice.
Zhang YY, Zhu DX, Wang MY, Yi YT, Feng YH, Zhou C, Li CJ, Liu F, Shen JF
Molecular neurobiology 2025 Jun;62(6):8013-8037
Molecular neurobiology 2025 Jun;62(6):8013-8037
Conjugated therapy with coaxially printed neural stem cell-laden microfibers and umbilical cord mesenchymal stem cell derived exosomes on complete transactional spinal cord defects.
Li X, Zhang J, Zhang Y, Guo L, Gao M, Wang Y, Qiu W, Yuan Y, Zhu J, Liu B, Xiong H, Xu T, Xu R
Materials today. Bio 2025 Jun;32:101639
Materials today. Bio 2025 Jun;32:101639
Glial inwardly rectifying potassium channel 4.1 regulates secretion of BDNF and GDNF via ERK1/2 MAP kinases in trigeminal neuropathic pain.
Lin J, Fang X, Ou M, Wang Z, Zhang X, Feng Y, Liu F, Zhang Y, Zhou C, Shen J
International journal of biological macromolecules 2025 Jun;317(Pt 1):144811
International journal of biological macromolecules 2025 Jun;317(Pt 1):144811
TMEM59 deficiency activates chaperone-mediated autophagy and ameliorates disease-like pathologies in tauopathy model mice.
Zheng N, Wang Z, Cao J, Li K, Xu H, Wang J, Zhang L, Meng J, Tang Z, Luo H, Sun H, Zhang X, Zhang YW
Alzheimer's & dementia : the journal of the Alzheimer's Association 2025 Jun;21(6):e70369
Alzheimer's & dementia : the journal of the Alzheimer's Association 2025 Jun;21(6):e70369
Effects of intermittent theta burst stimulation on the inflammatory response and cerebral blood flow in promoting neurovascular repair after ischemic stroke.
Zhang J, Li S, Huang D, Fu J, Chen S, Ren N, Yang P, Song D, Bai X, Xie H, Liu G, Yu K, Ng SSM, Wu J, Xiao X, Wu Y
Molecular brain 2025 Jun 9;18(1):48
Molecular brain 2025 Jun 9;18(1):48
Txnip/Trx Is a Potential Element in Regulating O-GlcNAc Modification in Photoreceptors to Alleviate Diabetic Retinopathy.
Imdad L, Xu S, Meng Y, Bao K, Dong W, Yin X, Tong Y, Zhang W, Ren X, Kong L
International journal of molecular sciences 2025 Jun 4;26(11)
International journal of molecular sciences 2025 Jun 4;26(11)
Visualization of P2X7 Receptors in Living Human Gliomas: An 18F-GSK1482160 PET Imaging and Neuropathology Study.
Zhou W, Yue Q, Yuan Y, Huang Q, He K, Hua T, Han J, He Y, Guan Y, Chen L, Xie F, Mao Y
Clinical cancer research : an official journal of the American Association for Cancer Research 2025 Jun 3;31(11):2183-2195
Clinical cancer research : an official journal of the American Association for Cancer Research 2025 Jun 3;31(11):2183-2195
Butyrate improves abnormal sleep architecture in a Parkinson's disease mouse model via BDNF/TrkB signaling.
Duan WX, Xie WY, Ying C, Fen W, Cheng XY, Mao CJ, Liu JY, Liu CF
NPJ Parkinson's disease 2025 Jun 19;11(1):175
NPJ Parkinson's disease 2025 Jun 19;11(1):175
Dingzhen pills inhibit neuronal ferroptosis and neuroinflammation by inhibiting the cGAS-STING pathway for Parkinson's disease mice.
Fu G, Li T, Zhao Y, Zhang S, Xue X, Yang Y, Li T, Luo S, Yue G, Lei T
Chinese medicine 2025 Jun 16;20(1):87
Chinese medicine 2025 Jun 16;20(1):87
The Anti-Parkinsonian A2A Receptor Antagonist Istradefylline (KW-6002) Attenuates Behavioral Abnormalities, Neuroinflammation, and Neurodegeneration in Cerebral Ischemia: An Adenosinergic Signaling Link Between Stroke and Parkinson's Disease.
Zaki MG, Jakova E, Pordeli M, Setork E, Taghibiglou C, Cayabyab FS
International journal of molecular sciences 2025 Jun 13;26(12)
International journal of molecular sciences 2025 Jun 13;26(12)
Excessive expression of progranulin leads to neurotoxicity rather than neuroprotection.
Kusakari S, Suzuki H, Nawa M, Sudo K, Yamazaki R, Miyagi T, Ohara T, Matsuoka M, Kanekura K
Neurobiology of disease 2025 Jun 1;209:106895
Neurobiology of disease 2025 Jun 1;209:106895
Exploring the dynamic pathogenesis of Parkinson's disease by case-control and longitudinal blood transcriptome analyses.
Xue G, Wang G, Shi Q, Wang H, Lv BM, Gao M, Niu X, Zhang HY
Neurobiology of disease 2025 Jun 1;209:106891
Neurobiology of disease 2025 Jun 1;209:106891
GABA-dependent microglial elimination of inhibitory synapses underlies neuronal hyperexcitability in epilepsy.
Chen ZP, Zhao X, Wang S, Cai R, Liu Q, Ye H, Wang MJ, Peng SY, Xue WX, Zhang YX, Li W, Tang H, Huang T, Zhang Q, Li L, Gao L, Zhou H, Hang C, Zhu JN, Li X, Liu X, Cong Q, Yan C
Nature neuroscience 2025 Jul;28(7):1404-1417
Nature neuroscience 2025 Jul;28(7):1404-1417
Anti-epileptic and gut-protective effects of trioctanoin and the critical role of gut microbiota in a mouse model of epilepsy.
Yu F, Ji JL, Wang Y, Liu YD, Lian YM, Wang MZ, Cai ZX
Brain research bulletin 2025 Jul;227:111401
Brain research bulletin 2025 Jul;227:111401
Visualizing bulk autophagy in vivo by tagging endogenous LC3B.
Gao X, Xiong Y, Ma H, Zhou H, Liu W, Sun Q
Autophagy 2025 Jul;21(7):1591-1607
Autophagy 2025 Jul;21(7):1591-1607
Optimally Aligned Nerve Scaffolds with Sustained Astaxanthin Release Improve the Inflammatory Microenvironment through Mitophagy Activation.
Jin X, Liu S, Fang J, Chen F, Xu B, Nan L, Zhao S, Wu Z, Guan Z, Tao K, Liu J
Small (Weinheim an der Bergstrasse, Germany) 2025 Jul;21(26):e2502939
Small (Weinheim an der Bergstrasse, Germany) 2025 Jul;21(26):e2502939
Refined qingkailing attenuates reactive astrocytes and glial scar formation after ischemia stroke via the EGFR/PLCγ pathway.
Ren ZL, Zhang CX, Zheng YX, Chen CA, Dan-Chen, Lan X, Yan X, Liu Y, He YH, Cheng JL, Han JH, Wang QG, Wang XQ, Cheng FF, Li CX
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul;142:156696
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul;142:156696
High precision and cost-effective multiplex quantification of amyloid-β40, amyloid-β42, p181Tau, p217Tau, neurofilament light chain, and glial fibrillary acidic protein from plasma and serum.
Alishahi F, Beam CR, Gatz M, Schneider LS, Nation DA, Yassine HN, Kaplan H, Ganesan S, Pappas I, Davis DW, Zandi E
Journal of Alzheimer's disease : JAD 2025 Jul;106(2):739-755
Journal of Alzheimer's disease : JAD 2025 Jul;106(2):739-755
Association of Hsa_circ_0059511 with the sensitivity of the temozolomide chemotherapeutic treatment in human glioma cells.
Chen Y, Cheng P, Huang W, Jing Y, Su J, Wu Z, Cai J
Scientific reports 2025 Jul 30;15(1):27761
Scientific reports 2025 Jul 30;15(1):27761
Cannabidiol ameliorates seizures and neuronal damage in ferric chloride-induced posttraumatic epilepsy by targeting TRPV1 channel.
Ma L, Gao Y, Chen J, Hai D, Yu J, Tang S, Liu N, Liu Y
Journal of ethnopharmacology 2025 Jul 24;351:120072
Journal of ethnopharmacology 2025 Jul 24;351:120072
Kai-Xin-San ameliorates fluoxetine-resistant depressive-like behaviors by modulating tryptophan-kynurenine metabolic homeostasis in a rodent model.
Yao L, Jing R, Wang C, Wang Y, Li X, Wu X, Wang Y, Liu L, Mu L, Liu P, Hu Y
Journal of ethnopharmacology 2025 Jul 24;351:120011
Journal of ethnopharmacology 2025 Jul 24;351:120011
Role of astrocytic mu-opioid receptors of the ventrolateral periaqueductal gray in modulating anxiety-like responses.
Du Y, Zhang A, Li Z, Zhao Y, Liu S, Wei C, Zheng Q, Qiao Y, Liu Y, Ren W, Han J, Liu Z, Gao F
Behavioral and brain functions : BBF 2025 Jul 23;21(1):24
Behavioral and brain functions : BBF 2025 Jul 23;21(1):24
Mild subcortical stroke induces widespread astrogliosis independent of microglia and age.
Stackhouse TL, Marxmiller BD, Sullivan SJ, McConnell HL, Knittel LM, De La Torre R, Houser A, Zhang W, Woltjer RL, Mishra A
bioRxiv : the preprint server for biology 2025 Jul 23;
bioRxiv : the preprint server for biology 2025 Jul 23;
Botulinum toxin type A inhibits microglia pyroptosis by suppressing Cblb-mediated degradation of Pdlim1 to attenuate neuropathic pain.
Tian S, Wu L, Zheng H, Cheng Z, Liu J, Liu M, Yu X, Tu J, Wu W
The journal of headache and pain 2025 Jul 22;26(1):165
The journal of headache and pain 2025 Jul 22;26(1):165
Dopamine Alleviated Diabetic Retinal Neurodegeneration through Protecting Retinal Ganglion Cells from Ferroptosis via the Nrf2/HO‑1 Signaling Pathway.
Rao S, Xiao K, Chen X, Sun X
ACS omega 2025 Jul 22;10(28):30397-30410
ACS omega 2025 Jul 22;10(28):30397-30410
Müller cells are activated in response to retinal outer nuclear layer degeneration in rats subjected to simulated weightlessness conditions.
Mu Y, Zhang N, Wei D, Yang G, Yao L, Xu X, Li Y, Xue J, Zhang Z, Chen T
Neural regeneration research 2025 Jul 1;20(7):2116-2128
Neural regeneration research 2025 Jul 1;20(7):2116-2128
A novel carbamate-based hybrid derivative with anti-neuroinflammatory properties as a selective butyrylcholinesterase inhibitor for Alzheimer's disease therapy.
Liu X, Xu J, Yu C, Dai C, Chen J, Zhong J, Yang Y, Lin H, Chen X, Zhang Q, Dai L, Zhang J, Zha D, Ye ZC
Bioorganic chemistry 2025 Jul 1;161:108551
Bioorganic chemistry 2025 Jul 1;161:108551
N-methyl-D-aspartate Receptor Subunits 2A and 2B Mediate Connexins and Pannexins in the Trigeminal Ganglion Involved in Orofacial Inflammatory Allodynia during Temporomandibular Joint Inflammation.
Li YL, Zhang YY, Song QX, Liu F, Liu YJ, Li YK, Zhou C, Shen JF
Molecular neurobiology 2025 Jan;62(1):1247-1265
Molecular neurobiology 2025 Jan;62(1):1247-1265
Microspheres of stem cells from human exfoliated deciduous teeth exhibit superior pulp regeneration capacity.
Ding J, Sun Z, Ma L, Wang L, Liao Z, Liang L, Yang H, Mao R
Dental materials : official publication of the Academy of Dental Materials 2025 Jan;41(1):70-80
Dental materials : official publication of the Academy of Dental Materials 2025 Jan;41(1):70-80
Gypenoside XLIX alleviates sepsis-associated encephalopathy by targeting PPAR-α.
Zhao P, Zhang W, Zhou X, Zhao Y, Li A, Sun Y
Experimental neurology 2025 Jan;383:115027
Experimental neurology 2025 Jan;383:115027
Cold atmospheric plasma-activated saline alleviates secondary injury post-SCI by inhibiting extracellular matrix remodeling and infiltration of proinflammatory macrophages.
Jiang Y, Wang LY, Liu Y, Li JJ, Zhang SQ, Feng XJ, Yang CJ, Zhou Y
Experimental neurology 2025 Jan;383:115004
Experimental neurology 2025 Jan;383:115004
Lactiplantibacillus plantarum SG5 inhibits neuroinflammation in MPTP-induced PD mice through GLP-1/PGC-1α pathway.
Qi Y, Dong Y, Chen J, Xie S, Ma X, Yu X, Yu Y, Wang Y
Experimental neurology 2025 Jan;383:115001
Experimental neurology 2025 Jan;383:115001
Magnolol acts as a neurorestorative agent in an A(β1‑42)‑induced mouse model of Alzheimer's disease.
Yu Q, Shi Y, Wu Y, Liu R, Zhang H, Wu L, Ding M
Experimental and therapeutic medicine 2025 Jan;29(1):12
Experimental and therapeutic medicine 2025 Jan;29(1):12
Bioactive Peptide Hydrogel Scaffold with High Fluidity, Thermosensitivity, and Neurotropism in 3D Spatial Structure for Promoted Repair of Spinal Cord Injury.
Sun Z, Luan X, Sun Z, Li D, Hu H, Xue Q, Liu B, Yu Q, Wei G, Zhang X, Xi Y
Small (Weinheim an der Bergstrasse, Germany) 2025 Jan;21(2):e2406990
Small (Weinheim an der Bergstrasse, Germany) 2025 Jan;21(2):e2406990
An Optimized Decellularized Extracellular Matrix from Dental Pulp Stem Cell Sheets Promotes Axonal Regeneration by Multiple Modes in Spinal Cord Injury Rats.
Qiu W, Zhou B, Luo Y, Chen Y, Chen Z, Wu K, Wu H, Wu B, Guo J, Fang F
Advanced healthcare materials 2025 Jan;14(1):e2402312
Advanced healthcare materials 2025 Jan;14(1):e2402312
Upregulation of delta opioid receptor by meningeal interleukin-10 prevents relapsing pain.
Inyang KE, Sim J, Clark KB, Geron M, Monahan K, Evans C, O'Connell P, Laumet S, Peng B, Ma J, Heijnen CJ, Dantzer R, Scherrer G, Kavelaars A, Bernard M, Aldhamen YA, Folger JK, Bavencoffe A, Laumet G
Brain, behavior, and immunity 2025 Jan;123:399-410
Brain, behavior, and immunity 2025 Jan;123:399-410
Astrocyte-neuron communication through the complement C3-C3aR pathway in Parkinson's disease.
Chi X, Yin S, Sun Y, Kou L, Zou W, Wang Y, Jin Z, Wang T, Xia Y
Brain, behavior, and immunity 2025 Jan;123:229-243
Brain, behavior, and immunity 2025 Jan;123:229-243
Astragaloside IV plays a neuroprotective role by promoting PPARγ in cerebral ischemia-reperfusion rats.
Ding Y, Jie K, Xin L, Shao B
Behavioural brain research 2025 Jan 5;476:115267
Behavioural brain research 2025 Jan 5;476:115267
The aqueous extract of Armadillidium vulgare Latreille alleviates neuropathic pain via inhibiting neuron-astrocyte crosstalk mediated by the IL-12-IFN-γ-IFNGR-CXCL10 pathway.
Yang Y, Zhang S, Yang J, Yao C, Li X, Dai W, Liu J
Journal of ethnopharmacology 2025 Jan 31;340:119173
Journal of ethnopharmacology 2025 Jan 31;340:119173
6-thioguanine inhibits EV71 replication by reducing BIRC3-mediated autophagy.
You Q, Wu J, Lyu R, Cai Y, Jiang N, Liu Y, Zhang F, He Y, Chen D, Wu Z
BMC microbiology 2025 Jan 29;25(1):53
BMC microbiology 2025 Jan 29;25(1):53
Trehalose enhances macrophage autophagy to promote myelin debris clearance after spinal cord injury.
Ma Z, Meng C, Wang X, Zhao Y, Wang J, Chen Y, Li Y, Jiang Y, Ouyang F, Li J, Zheng M, Cheng L, Jing J
Cell & bioscience 2025 Jan 29;15(1):11
Cell & bioscience 2025 Jan 29;15(1):11
Altered ATP13A2/PARK9 Levels Influence α-Synuclein Accumulation in Neurons via Phagocytosis and Secretion in Glial Cells.
Tsunemi T, Ishiguro Y, Yoroisaka A, Feng D, Hattori N
Cells 2025 Jan 22;14(3)
Cells 2025 Jan 22;14(3)
Electrophysiology-based screening identifies neuronal HtrA serine peptidase 2 (HTRA2) as a synaptic plasticity regulator participating in tauopathy.
Zheng N, Li K, Cao J, Wang Z, Zhang L, Zhao Z, He J, Wang Y, Zhu X, Chen Y, Meng J, Zhao D, Niu M, Luo H, Zhang X, Sun H, Zhang YW
Translational psychiatry 2025 Jan 10;15(1):5
Translational psychiatry 2025 Jan 10;15(1):5
NLRP3 inhibitor alleviates glycemic variability-induced cognitive impairment in aged rats with type 2 diabetes mellitus.
Yang W, Si SC, Li J, Ma YX, Zhao H, Liu J
Molecular and cellular endocrinology 2025 Jan 1;595:112406
Molecular and cellular endocrinology 2025 Jan 1;595:112406
Enhanced neural activity detection with microelectrode arrays modified by drug-loaded calcium alginate/chitosan hydrogel.
Wang Y, Han M, Jing L, Jia Q, Lv S, Xu Z, Liu J, Cai X
Biosensors & bioelectronics 2025 Jan 1;267:116837
Biosensors & bioelectronics 2025 Jan 1;267:116837
Blood glucose and β-hydroxybutyrate predict significant brain injury after hypoxia-ischemia in neonatal mice.
Duck SA, Nazareth M, Fassinger A, Pinto C, Elmore G, Nugent M, St Pierre M, Vannucci SJ, Chavez-Valdez R
Pediatric research 2025 Feb;97(2):798-808
Pediatric research 2025 Feb;97(2):798-808
CircKat6b Mediates the Antidepressant Effect of Esketamine by Regulating Astrocyte Function.
Hu N, Zheng Y, Liu X, Jia J, Feng J, Zhang C, Liu L, Wang X
Molecular neurobiology 2025 Feb;62(2):2587-2600
Molecular neurobiology 2025 Feb;62(2):2587-2600
DHA Improves neurodevelopmental abnormalities in offspring of gestational diabetes mellitus patients via the PPAR-γ/FATP4 pathway.
Jiang Y, Zhou X, He Z, Wei L, Zhu S, Zhang H, Zhang J, Chen Y, Du Y, Ding W, Wang S, Wang Z, Feng L
Biochemical pharmacology 2025 Feb;232:116726
Biochemical pharmacology 2025 Feb;232:116726
Microglia-Derived Vitamin D Binding Protein Mediates Synaptic Damage and Induces Depression by Binding to the Neuronal Receptor Megalin.
Kong Y, Zhang X, Li L, Zhao T, Huang Z, Zhang A, Sun Y, Jiao J, Zhang G, Liu M, Han Y, Yang L, Zhang Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Feb;12(6):e2410273
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Feb;12(6):e2410273
HSPA1A inhibits pyroptosis and neuroinflammation after spinal cord injury via DUSP1 inhibition of the MAPK signaling pathway.
He X, Deng B, Zhang C, Zhang G, Yang F, Zhu D, Yang Y, Ma B, Hu X, Wang Y, Kang X
Molecular medicine (Cambridge, Mass.) 2025 Feb 9;31(1):53
Molecular medicine (Cambridge, Mass.) 2025 Feb 9;31(1):53
Nasal mucosal mesenchymal stem cells promote repair of sciatic nerve injury in rats by modulating the inflammatory microenvironment.
Tang Y, Li Y, Yang W, Tao Z, Shi W, Yu M, Xu B, Lu X
Neuroscience letters 2025 Feb 6;848:138112
Neuroscience letters 2025 Feb 6;848:138112
A visual cortical-lateral posterior thalamic nucleus circuit regulates depressive-like behaviors in male mice.
Wu F, Gu C, Xu R, Ma J, Gao L, Zhang Y, Bu S, Lu Q, Zhao T, Han Y, Guo C, Cui Y, Ding J, Hu G, Zhang Z
Nature communications 2025 Feb 6;16(1):1395
Nature communications 2025 Feb 6;16(1):1395
Radiation damage to a three-dimensional hydrogel model of the brain perivascular niche.
Ivanova YI, Nunes AC, Cruz V, Selting K, Harley BAC
bioRxiv : the preprint server for biology 2025 Feb 26;
bioRxiv : the preprint server for biology 2025 Feb 26;
Glutamatergic argonaute2 promotes the formation of the neurovascular unit in mice.
Sona C, Yeh YT, Li Y, Liu X, Ghosh A, Hinte LC, Ku MC, Rathjen T, Niendorf T, Yu G, Jia S, Kononenko NL, Hermann A, Luo J, Lin J, von Meyenn F, Yan X, Poy MN
Science signaling 2025 Feb 25;18(875):eadl6745
Science signaling 2025 Feb 25;18(875):eadl6745
3-N-Butylphthalide alleviate Aβ-induced cellular senescence through the CDK2-pRB1-Caspase3 axis.
Tian Y, Li W, Zhang Y
Brain research 2025 Feb 15;1849:149435
Brain research 2025 Feb 15;1849:149435
Nrf2 activator tertiary butylhydroquinone enhances neural stem cell differentiation and implantation in Alzheimer's disease by boosting mitochondrial function.
Lin L, Li J, Yu Z, He J, Li Y, Jiang J, Xia Y
Brain research 2025 Feb 15;1849:149341
Brain research 2025 Feb 15;1849:149341
NSAID-mediated cyclooxygenase inhibition disrupts ectodermal derivative formation in axolotl embryos.
Marshall EJ, Ramarapu R, Leathers TA, Morrison-Welch N, Sandberg K, Kawashima M, Rogers CD
bioRxiv : the preprint server for biology 2025 Feb 15;
bioRxiv : the preprint server for biology 2025 Feb 15;
PD-1 Attenuates Neuropathic Pain by Ameliorating NLRP3 Inflammasome-Mediated Microglia Pyroptosis.
Deng D, Ma L, Shen J, Huang L, Zhang T, Yang X, Huang S, Zhao W, Zhou Y, Fan S, Wang K, Chen X
Molecular neurobiology 2025 Dec;62(12):15478-15493
Molecular neurobiology 2025 Dec;62(12):15478-15493
Multi-omics analysis delineates molecular signatures of spinal ependymal tumor.
Liu W, Ning C, Geng X, Wang B, Zhang Y, Wang C, Liu Y, Zheng G, Wang Y, Wang X, Li D, Jia W
Cellular oncology (Dordrecht, Netherlands) 2025 Dec;48(6):1987-2000
Cellular oncology (Dordrecht, Netherlands) 2025 Dec;48(6):1987-2000
Transglutaminase-2 Promotes Microglial Synaptic Phagocytosis and Ameliorates Epileptic Seizures by Inhibiting ABCA1 Ubiquitination.
Zhou Z, Wang X, Yang J, Qin J, Feng B, Qin Q, Tian J, Luo Z, Yang X, Huang H, Xu X, Li J, Xu Z, Yu C, Zhang H
CNS neuroscience & therapeutics 2025 Dec;31(12):e70725
CNS neuroscience & therapeutics 2025 Dec;31(12):e70725
The potential of taVNS in attenuating blood-brain barrier damage, promoting angiogenesis and improving impaired cognitive function in a rat model of vascular cognitive impairment and dementia by activating the Wnt7/β-catenin signaling pathway.
Sun R, Li H, Wang M, Yan L, Jiang J, Liu Q, Li S, Liang Y, Qian Y, Yu T
Autonomic neuroscience : basic & clinical 2025 Dec;262:103353
Autonomic neuroscience : basic & clinical 2025 Dec;262:103353
Dietary cholesterol impairs cognition via gut microbiota-derived deoxycholic acid in obese mice.
Liu Y, Wang Z, Zhang Y, Zhao T, Zhang Q, Huang W, Lu B
Gut microbes 2025 Dec;17(1):2537753
Gut microbes 2025 Dec;17(1):2537753
Metabolic Remodeling During the Early Phase of Spontaneous Seizure Emergence Highlights Hexosamine Biosynthetic Pathway Dysregulation in Temporal Lobe Epilepsy.
Zhao Z, Zhang YF, Xu LQ, Zhong MK, Ma CL
Journal of neurochemistry 2025 Dec;169(12):e70314
Journal of neurochemistry 2025 Dec;169(12):e70314
Pharmacokinetic and Pharmacodynamic Evaluation of PZ-2891, an Anti-Alzheimer's Disease Agonist of PANK2.
Chen Y, Ma H, Jin M, Zhang S, Qu S, Wang G, Aa J
Pharmaceuticals (Basel, Switzerland) 2025 Dec 9;18(12)
Pharmaceuticals (Basel, Switzerland) 2025 Dec 9;18(12)
Soluble CSF1R alleviates microgliopathy in a CSF1R-related leukoencephalopathy (CRL) mouse model.
Zhou Y, Hu B, Luo J, Wang X, Huang X, Li Y, Zhang X, Bu G, Zhang H, Zhang YW, Zheng H
Journal of neuroinflammation 2025 Dec 5;23(1):12
Journal of neuroinflammation 2025 Dec 5;23(1):12
Microglia-specific interleukin-4 delivery by engineered extracellular vesicles restores inner blood-retinal barrier in diabetic retinopathy via GAS6-MERTK pathway.
Fan Y, Ge P, Wang X, Xu J, Wang J, Li H, Gu Q, Xie H, Lin Y, Lu Y, Wang C, Xie P, Hu Z
Journal of nanobiotechnology 2025 Dec 29;24(1):101
Journal of nanobiotechnology 2025 Dec 29;24(1):101
Astroglial kappa opioid receptor-mediated reduction of glutamate exchanger xCT in the prelimbic cortex underlies chronic stress-induced depressive-like behaviors.
Chen Y, Guo LB, Zan GY, Xu C, Yao SY, Wu S, Jiang X, Liu Z, Long JD, Liu B, He X, Shao X, Fang J, Liu JG, Wang YJ
Molecular psychiatry 2025 Dec 24;
Molecular psychiatry 2025 Dec 24;
Promoting astrocyte-neuron triiodothyronine shuttling attenuates brain damage in neonatal hypoxic-ischemic encephalopathy.
Yu G, Yang Y, Zhou W, Wang X, Feng Y, Wang X, Lin Z
Journal of neuroinflammation 2025 Dec 2;23(1):5
Journal of neuroinflammation 2025 Dec 2;23(1):5
Treadmill Exercise Modulates the Leptin/LepR/GSK-3β Signalling Pathway to Improve Leptin Sensitivity and Alleviate Neuroinflammation in High-Fat Diet-Fed APP/PS1 Mice.
Wang J, Liao M, Tong Z, Yuan S, Hu Z, Chen Z, Zeng F, Zou R, Chen D, Chen G, Wang Z, Liu W
Molecular neurobiology 2025 Aug;62(8):9651-9669
Molecular neurobiology 2025 Aug;62(8):9651-9669
Upregulating mTOR/S6 K Pathway by CASTOR1 Promotes Astrocyte Proliferation and Myelination in Gpam(-/-)-induced mouse model of cerebral palsy.
Chen Z, Liu L, Guo X, Zhang Y, Zhong M, Xu Y, Peng T Sr, Peng T Jr, Zhang Y, Hou Q, Fan D, Gao T, He L, Tang H, Hu H, Xu K
Molecular neurobiology 2025 Aug;62(8):10724-10741
Molecular neurobiology 2025 Aug;62(8):10724-10741
Inhibiting NLRP3 Inflammasome Activation to Alleviate Retinal Inflammation and Protect the Optic Nerve of OPTN(E50K)Mice.
Wang S, Xiao R, Lu Y, Zhang Y, Zhang S, Liu X, Yuan H
Inflammation 2025 Aug;48(4):2105-2121
Inflammation 2025 Aug;48(4):2105-2121
Exploring the molecular mechanism of icariin improving spinal cord injury through network pharmacology combined with experimental verification.
Zhou M, Jiang Z, Zhang M, Feng S, Ma B, Kan S, Fu X, Zhu R
Naunyn-Schmiedeberg's archives of pharmacology 2025 Aug;398(8):10539-10556
Naunyn-Schmiedeberg's archives of pharmacology 2025 Aug;398(8):10539-10556
Synergistic microglial modulation by laminarin-based platinum nanozymes for potential intracerebral hemorrhage therapy.
Guo X, Zheng Q, Gao W, Xiao Y, Shi L, Lin F, Xiong Y, Zhang Y, Xu Q, Wang L, He S, Zheng F
Biomaterials 2025 Aug;319:123212
Biomaterials 2025 Aug;319:123212
Electroacupuncture Improves Microglial Polarization Induced-Inflammation by Regulating the TGF-β/Smad-3 Signaling Pathway in Ischemic Stroke Mice.
Yang G, Zhang L, Yuan Y, Mazhar M, Zhang D, Liu Y, Chen G, Fan X
CNS neuroscience & therapeutics 2025 Aug;31(8):e70567
CNS neuroscience & therapeutics 2025 Aug;31(8):e70567
The Role of the cGAS/STING Pathway in Arsenic-Induced Neurotoxicity: Insights from the Crosstalk Between Astrocytes and Neurons.
Luo D, Sun B, Wang W, Zhang A
Biological trace element research 2025 Aug;203(8):4224-4239
Biological trace element research 2025 Aug;203(8):4224-4239
Targeting CDK1 inhibits Golgi apparatus stress-mediated neuroinflammation and neuronal apoptosis after intracerebral hemorrhage by modulating GRASP55 phosphorylation.
Zhang X, Yang M, Jiang F, Wang Y, Zhou Z, Wu Z
Cellular signalling 2025 Aug;132:111835
Cellular signalling 2025 Aug;132:111835
Sex-dependent behavioral and neuronal alterations in the F2 generation of a neurodevelopmental mouse model for schizophrenia.
Wang YC, Huang YY, E ED, Fu CX, Li JW, Mi YW, Zhong N, Yang FR, Zhang T, Xu LM, Zhang XQ
Progress in neuro-psychopharmacology & biological psychiatry 2025 Aug 30;141:111476
Progress in neuro-psychopharmacology & biological psychiatry 2025 Aug 30;141:111476
Glycosides of Buyang Huanwu decoction alleviate cerebral infarction injury by inhibiting neuronal pyroptosis via astrocyte-derived exosomal miR-378b_L+1.
Lang T, Qin K, Shao L, Fan B, Chen H, Yu B, Li S, Xie Y, Liao Y, Hu J, Sun R, Zhong Z, Deng C, She Y
Journal of ethnopharmacology 2025 Aug 29;352:120234
Journal of ethnopharmacology 2025 Aug 29;352:120234
Activated Schwann cells promote tumor growth in colon cancer.
He K, Wang H, Wu H, Li W, Huo R, Jiang L, Yu M, Xue J
Cancer letters 2025 Aug 28;626:217791
Cancer letters 2025 Aug 28;626:217791
Preventive and therapeutic effects of Tanshinone IIA on spinal cord injury without radiographic abnormality by regulating microglial phenotype polarization.
Xu L, Ma Y, Jiang G, Cao Z, Song J, Gao Y, Wang G, Fan J, Yang Y, Yu X
International immunopharmacology 2025 Aug 28;161:115086
International immunopharmacology 2025 Aug 28;161:115086
Cyclooxygenase-1 deletion in 5 × FAD mice protects against microglia-induced neuroinflammation and mitigates cognitive impairment.
Wang J, Ni H, Wang Y, Wei L, Ding H, Guo Z, Pan H, Yu Y, Luo J, Pan W, Wang D, Ke ZJ
Translational neurodegeneration 2025 Aug 22;14(1):43
Translational neurodegeneration 2025 Aug 22;14(1):43
Cerebral blood flow in elastin haploinsufficient and 3xTg-AD mice.
Cullen AE, Reeve EH, Winder NR, Henson GD, Arora N, Leonhardt T, Hogan A, Kumaran SK, Setthavonsack N, Krajbich V, Alkayed NJ, Pike MM, Woltjer RL, Walker AE
bioRxiv : the preprint server for biology 2025 Aug 22;
bioRxiv : the preprint server for biology 2025 Aug 22;
An ancient enhancer rapidly evolving in the human lineage promotes neural development and cognitive flexibility.
Tan K, Higgins K, Liu Q, Wilkinson MF
Science advances 2025 Aug 15;11(33):eadt0534
Science advances 2025 Aug 15;11(33):eadt0534
FGF21 Alleviates Hypoxic-Ischemic White Matter Injury in Neonatal Mice by Mediating Inflammation and Oxidative Stress Through PPAR-γ Signaling Pathway.
Fang M, Lu L, Lou J, Ou J, Yu Q, Tao X, Zhu J, Lin Z
Molecular neurobiology 2025 Apr;62(4):4743-4768
Molecular neurobiology 2025 Apr;62(4):4743-4768
RvE1/ChemR23 facilitates hematoma clearance and promotes M2 polarization of macrophages/microglia in intracerebral hemorrhage.
Fang M, Xia F, Teng B, Xia W, Yang Y, Wang J, Tao C, Hu X
Experimental neurology 2025 Apr;386:115173
Experimental neurology 2025 Apr;386:115173
Targeted sonodynamic therapy induces tumor cell quasi-immunogenic ferroptosis and macrophage immunostimulatory autophagy in glioblastoma.
Wang MF, Guo J, Yuan SJ, Li K, Zhang Q, Lei HM, Wu JL, Zhao L, Xu YH, Chen X
Biomaterials 2025 Apr;315:122913
Biomaterials 2025 Apr;315:122913
Recombinant human heavy-chain ferritin nanoparticles loaded with rosuvastatin attenuates secondary brain injury in intracerebral hemorrhage.
Guo T, Wang Y, Hayat MA, Si Y, Ni Y, Zhang J, Qiu Y, Zeng Y, Cao Y, Hong Y, Chen B, Hu J
International journal of biological macromolecules 2025 Apr;302:140542
International journal of biological macromolecules 2025 Apr;302:140542
Shuangxia Decoction attenuates sleep disruption in 5×FAD mice through neuroinflammation inhibition: An integrative analysis of transcriptomic and molecular biology investigations.
Wang J, Pan H, Tang H, Zhang J, Li T, Liu Y, Huang Y, Fei Z, Wang Y
Journal of ethnopharmacology 2025 Apr 9;345:119642
Journal of ethnopharmacology 2025 Apr 9;345:119642
Macrophage migration inhibitory factor in the mouse hippocampus promotes neuroinflammation and cognitive dysfunction following anesthesia and surgery.
Zeng L, Hu PC, Zhang Y, Han TT, Wang X, Zhao YL, Li SY, Luo AL
International immunopharmacology 2025 Apr 4;151:114351
International immunopharmacology 2025 Apr 4;151:114351
Melatonin alleviates retinal injury induced by vigabatrin and partially enhances its antiepileptic effects.
Ma M, Fan M, Xu S, Zheng Q, Wang C, Chen P, Wei Y, Ge J
International immunopharmacology 2025 Apr 24;153:114516
International immunopharmacology 2025 Apr 24;153:114516
Pkd2l1 deletion inhibits the neurogenesis of cerebrospinal fluid-contacting neurons and impedes spinal cord injury repair.
Zhang Y, Cao L, Yan H, Luo Z, Chen C, Shangguan Z, Li Q, Shi X, Yang L, Tan W, Yang S, Fu J, Wang C, Dou X, Li Q
Cell death discovery 2025 Apr 23;11(1):194
Cell death discovery 2025 Apr 23;11(1):194
Luteolin attenuates cadmium neurotoxicity by suppressing glial inflammation and supporting neuronal survival.
Ma HY, Wang J, Wang J, Guo Z, Qin XY, Lan R, Hu Y
International immunopharmacology 2025 Apr 16;152:114406
International immunopharmacology 2025 Apr 16;152:114406
Anxiolytic effects of accelerated continuous theta burst stimulation on mice exposed to chronic restraint stress and the underlying mechanism involving gut microbiota.
Wang Y, Guo C, Zang B, Wang P, Yang C, Shi R, Kong Y, Sui A, Li S, Lin Y
Journal of affective disorders 2025 Apr 15;375:49-63
Journal of affective disorders 2025 Apr 15;375:49-63
VEGF secreted by human dental pulp stem cell promotes spinal cord injury repair by inhibiting microglial pyroptosis through the PI3K/AKT pathway.
Zhang X, Liu T, Ma Z, Li G, Ding N, Wang Z, Guan Y, Zhang Y, Liu L, Chen X
Journal of translational medicine 2025 Apr 12;23(1):437
Journal of translational medicine 2025 Apr 12;23(1):437
Electroacupuncture Serum Alleviates Ogd/R-Induced Astrocyte Damage by Regulating the AQP4 Via m6A Methylation of lncRNA MALAT1.
Zhang H, Xu X, Li X, Zeng C, Peng Y
Neurochemical research 2025 Apr 10;50(2):139
Neurochemical research 2025 Apr 10;50(2):139
The development and potent antitumor efficacy of CD44/CD133 dual-targeting IL7Rα-armored CAR-T cells against glioblastoma.
Zhai Y, Li G, Pan C, Yu M, Hu H, Wang D, Shi Z, Jiang T, Zhang W
Cancer letters 2025 Apr 1;614:217541
Cancer letters 2025 Apr 1;614:217541
UCH-L1 Inhibitor Alleviates Nerve Damage Caused by Moyamoya Disease.
Xu M, Zhao X, Zhao J, Tan Z, Zhang C, Huang Y, Zhong H, Guo M, Zhang C, Ye P, Zheng W
Applied bionics and biomechanics 2024;2024:2550642
Applied bionics and biomechanics 2024;2024:2550642
Perioperative enriched environment attenuates postoperative cognitive dysfunction by upregulating microglia TREM2 via PI3K/Akt pathway in mouse model of ischemic stroke.
Yao Y, Hu L, Li D, Wang Y, Pan J, Fan D
Frontiers in neuroscience 2024;18:1520710
Frontiers in neuroscience 2024;18:1520710
Propofol and Dexmedetomidine Ameliorate Endotoxemia-Associated Encephalopathy via Inhibiting Ferroptosis.
Zhou Y, Yang Y, Yi L, Pan M, Tang W, Duan H
Drug design, development and therapy 2024;18:1349-1368
Drug design, development and therapy 2024;18:1349-1368
Epileptic seizures induced by pentylenetetrazole kindling accelerate Alzheimer-like neuropathology in 5×FAD mice.
Zou Y, Wang C, Li H, Zhong M, Lin J, Hu Y, Chen Z, Gan CL
Frontiers in pharmacology 2024;15:1500105
Frontiers in pharmacology 2024;15:1500105
Salidroside ameliorates cerebral ischemic injury and regulates the glutamate metabolism pathway in astrocytes.
Zheng X, Zhang H, Zhang Y, Ding Z, Huang Z, Li H, Yao M, Song W, Liu J
Frontiers in pharmacology 2024;15:1472100
Frontiers in pharmacology 2024;15:1472100
Microglial adenosine A(2A) receptor in the paraventricular thalamic nucleus regulates pain sensation and analgesic effects independent of opioid and cannabinoid receptors.
Cao Y, Wu Z, Zhang M, Ji R, Zhang H, Song L
Frontiers in pharmacology 2024;15:1467305
Frontiers in pharmacology 2024;15:1467305
Astrocyte-derived exosomal miR-378a-5p mitigates cerebral ischemic neuroinflammation by modulating NLRP3-mediated pyroptosis.
Sun R, Liao W, Lang T, Qin K, Jiao K, Shao L, Deng C, She Y
Frontiers in immunology 2024;15:1454116
Frontiers in immunology 2024;15:1454116
Exploring the multifaceted therapeutic mechanism of Schisanlactone E (XTS) in APP/PS1 mouse model of Alzheimer's disease through multi-omics analysis.
Song Z, He J, Yu W, He C, Yang M, Li P, Li Z, Jian G, Cheng S
Frontiers in microbiology 2024;15:1440564
Frontiers in microbiology 2024;15:1440564
Effect of Dl-3-n-Butylphthalide on olfaction in rotenone-induced Parkinson's rats.
Wang J, Li H, Wang C, Li D, Zhang Y, Shen M, Xu X, Wu T
Frontiers in neurology 2024;15:1367973
Frontiers in neurology 2024;15:1367973
Vagal innervation limits brain injury by inhibiting gut-selective integrin-mediated intestinal immunocyte migration in intracerebral hemorrhage.
Fu P, Zong Y, Dai Y, Zhu L, Chen S, Rastegar-Kashkooli Y, Wang J, Zhang J, Wang J, Jiang C
Theranostics 2024;14(19):7383-7404
Theranostics 2024;14(19):7383-7404
MCT1-mediated endothelial cell lactate shuttle as a target for promoting axon regeneration after spinal cord injury.
Shi C, Xu J, Ding Y, Chen X, Yuan F, Zhu F, Duan C, Hu J, Lu H, Wu T, Jiang L
Theranostics 2024;14(14):5662-5681
Theranostics 2024;14(14):5662-5681
Exosomes Derived from Meningitic Escherichia coli-Infected Brain Microvascular Endothelial Cells Facilitate Astrocyte Activation.
Yang R, Qu X, Zhi S, Wang J, Fu J, Tan C, Chen H, Wang X
Molecular neurobiology 2024 Sep;61(9):7195-7210
Molecular neurobiology 2024 Sep;61(9):7195-7210
Endothelial lincRNA-p21 alleviates cerebral ischemia/reperfusion injury by maintaining blood-brain barrier integrity.
Zhao YH, Liang Y, Wang KJ, Jin SN, Yu XM, Zhang Q, Wei JY, Liu H, Fang WG, Zhao WD, Li Y, Chen YH
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2024 Sep;44(9):1532-1550
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2024 Sep;44(9):1532-1550
Distinct biological characteristics of mesenchymal stem cells separated from different components of human placenta.
Deng X, Zhang S, Qing Q, Wang P, Ma H, Ma Q, Zhao W, Tang H, Lu M
Biochemistry and biophysics reports 2024 Sep;39:101739
Biochemistry and biophysics reports 2024 Sep;39:101739
Irisflorentin improves functional recovery after spinal cord injury by protecting the blood-spinal cord barrier and promoting axonal growth.
Hu Z, Tan H, Zhang Y, Qi T, Li Y, Li N, Zhou Z, Wang Y, Wang H, Zhang H, Wang Q
Experimental neurology 2024 Sep;379:114886
Experimental neurology 2024 Sep;379:114886
Restoration of defective oxidative phosphorylation to a subset of neurons prevents mitochondrial encephalopathy.
Walker BR, Theard LM, Pinto M, Rodriguez-Silva M, Bacman SR, Moraes CT
EMBO molecular medicine 2024 Sep;16(9):2210-2232
EMBO molecular medicine 2024 Sep;16(9):2210-2232
The RhoB p.S73F mutation leads to cerebral palsy through dysregulation of lipid homeostasis.
Wu X, Liu R, Zhang Z, Yang J, Liu X, Jiang L, Fang M, Wang S, Lai L, Song Y, Li Z
EMBO molecular medicine 2024 Sep;16(9):2002-2023
EMBO molecular medicine 2024 Sep;16(9):2002-2023
Withaferin A protects against epilepsy by promoting LCN2-mediated astrocyte polarization to stopping neuronal ferroptosis.
Zhou Z, Zhang P, Ya D, Liu J, Xu Y, Zhang Y, Tang W, Zhou D, Liao R, Liu L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155892
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155892
Acetate enables metabolic fitness and cognitive performance during sleep disruption.
He Q, Ji L, Wang Y, Zhang Y, Wang H, Wang J, Zhu Q, Xie M, Ou W, Liu J, Tang K, Lu K, Liu Q, Zhou J, Zhao R, Cai X, Li N, Cao Y, Li T
Cell metabolism 2024 Sep 3;36(9):1998-2014.e15
Cell metabolism 2024 Sep 3;36(9):1998-2014.e15
SOLID: minimizing tissue distortion for brain-wide profiling of diverse architectures.
Zhu J, Liu X, Liu Z, Deng Y, Xu J, Liu K, Zhang R, Meng X, Fei P, Yu T, Zhu D
Nature communications 2024 Sep 27;15(1):8303
Nature communications 2024 Sep 27;15(1):8303
Investigation of Persistent Photoconductivity of Gallium Nitride Semiconductor and Differentiation of Primary Neural Stem Cells.
Meng Y, Du X, Zhou S, Li J, Feng R, Zhang H, Xu Q, Zhao W, Liu Z, Zhong H
Molecules (Basel, Switzerland) 2024 Sep 19;29(18)
Molecules (Basel, Switzerland) 2024 Sep 19;29(18)
Ginsenoside compound K alleviates D-galactose-induced mild cognitive impairment by modulating gut microbiota-mediated short-chain fatty acid metabolism.
Yan X, Bai X, Fu R, Duan Z, Zeng W, Zhu C
Food & function 2024 Sep 16;15(18):9037-9052
Food & function 2024 Sep 16;15(18):9037-9052
Cell-Type-Specific Expression of Leptin Receptors in the Mouse Forebrain.
Canepa CR, Kara JA, Lee CC
International journal of molecular sciences 2024 Sep 12;25(18)
International journal of molecular sciences 2024 Sep 12;25(18)
Differential toxic and antiepileptic features of Vigabatrin raceme and its enantiomers.
Xu SL, Fan M, Ma MD, Zheng Q, Chen PQ, Wei YD, Sun HM, Sun HZ, Ge JF
Brain research 2024 Sep 1;1838:148991
Brain research 2024 Sep 1;1838:148991
Stereotactically intracerebral transplantation of neural stem cells for ischemic stroke attenuated inflammatory responses and promoted neurogenesis: an experimental study with monkeys.
Liu YF, Liu HT, Chang C, Yang CX, Liu XN, Wang X, Ge W, Wang RZ, Bao XJ
International journal of surgery (London, England) 2024 Sep 1;110(9):5417-5433
International journal of surgery (London, England) 2024 Sep 1;110(9):5417-5433
Ferroptosis contributes to diabetes-induced visual pathway neuronal damage via iron accumulation and GPX4 inactivation.
Wang B, Jin Y, Ouyang X, Zhu R, Wang X, Li S, Jiang F
Metabolic brain disease 2024 Oct;39(7):1459-1468
Metabolic brain disease 2024 Oct;39(7):1459-1468
Curcumin attenuated neuroinflammation via the TLR4/MyD88/NF-κB signaling way in the juvenile rat hippocampus following kainic acid-induced epileptic seizures.
Fang Q, Cai Y, Yang Y, Zhang J, Ke J, Luo J, Zheng Y, Zhang Z, Alidu AJ, Wang Q, Huang X
Metabolic brain disease 2024 Oct;39(7):1387-1403
Metabolic brain disease 2024 Oct;39(7):1387-1403
Anti-CRMP2 antibody induces anxiety-like behavior and increases pyramidal neuron excitability in mice.
Pan Y, Jiang Y, Wang D, Guo Z, He F, Chen Z, Dai C, Yuan Z, Chen R, Xu K, Hu Y
Biochimica et biophysica acta. Molecular basis of disease 2024 Oct;1870(7):167338
Biochimica et biophysica acta. Molecular basis of disease 2024 Oct;1870(7):167338
Role of mitochondrial dysfunction and biogenesis in fibromyalgia syndrome: Molecular mechanism in central nervous system.
Marino Y, Inferrera F, D'Amico R, Impellizzeri D, Cordaro M, Siracusa R, Gugliandolo E, Fusco R, Cuzzocrea S, Di Paola R
Biochimica et biophysica acta. Molecular basis of disease 2024 Oct;1870(7):167301
Biochimica et biophysica acta. Molecular basis of disease 2024 Oct;1870(7):167301
The effects of BMP2 and the mechanisms involved in the invasion and angiogenesis of IDH1 mutant glioma cells.
Xu H, Cao Y, Ruan J, Wang F, He Y, Yang L, Yu T, Du F, Zhang N, Cao X
Journal of neuro-oncology 2024 Oct;170(1):161-171
Journal of neuro-oncology 2024 Oct;170(1):161-171
Novel in vivo TDP-43 stress reporter models to accelerate drug development in ALS.
Ferro F, Wolf CR, Henstridge C, Inesta-Vaquera F
Open biology 2024 Oct;14(10):240073
Open biology 2024 Oct;14(10):240073
Mechanically adaptive and deployable intracortical probes enable long-term neural electrophysiological recordings.
Wang S, Jiang Q, Liu H, Yu C, Li P, Pan G, Xu K, Xiao R, Hao Y, Wang C, Song J
Proceedings of the National Academy of Sciences of the United States of America 2024 Oct;121(40):e2403380121
Proceedings of the National Academy of Sciences of the United States of America 2024 Oct;121(40):e2403380121
Clinical characteristics of double negative atypical inflammatory demyelinating disease: A prospective study.
Jiang F, Cai H, Li H, Yin W, Ouyang S, Hu J, Tu E, Fu K, Yin J, Zhao Z, Yang J, Zeng Q, Yang H
Annals of clinical and translational neurology 2024 Oct;11(10):2769-2784
Annals of clinical and translational neurology 2024 Oct;11(10):2769-2784
CX3CR1(+)/UCHL1(+) microglial extracellular vesicles in blood: a potential biomarker for multiple sclerosis.
Duan J, Lv A, Guo Z, Liu Q, Tian C, Yang Y, Bi J, Yu X, Peng G, Luo B, Cai Z, Xu B, Fu Y, Zhang J
Journal of neuroinflammation 2024 Oct 9;21(1):254
Journal of neuroinflammation 2024 Oct 9;21(1):254
Ferroptosis Regulated by 5-HT3a Receptor via Calcium/Calmodulin Signaling Contributes to Neuropathic Pain in Brachial Plexus Avulsion Rat Models.
Liao C, Guo J, Li S, Rui J, Gao K, Lao J, Zhou Y
ACS chemical neuroscience 2024 Oct 6;
ACS chemical neuroscience 2024 Oct 6;
Extracellular vesicles from neural stem cells safeguard neurons in intracerebral hemorrhage by suppressing reactive astrocyte neurotoxicity.
Li T, Zhang L, Wang P, Yu J, Zhong J, Tang Q, Zhu T, Chen K, Li F, Hong P, Wei J, Sun X, Ji G, Song B, Zhu J
Cell reports 2024 Oct 22;43(10):114854
Cell reports 2024 Oct 22;43(10):114854
Targeting exosomal double-stranded RNA-TLR3 signaling pathway attenuates morphine tolerance and hyperalgesia.
Wang B, Le DS, Liu L, Zhang XX, Yang F, Lai GR, Zhang C, Zhao ML, Shen YP, Liao PS, Liu T, Liang YP
Cell reports. Medicine 2024 Oct 15;5(10):101782
Cell reports. Medicine 2024 Oct 15;5(10):101782
TBC1D15-regulated mitochondria-lysosome membrane contact exerts neuroprotective effects by alleviating mitochondrial calcium overload in seizure.
Xie Y, Zhang W, Peng T, Wang X, Lian X, He J, Wang C, Xie N
Scientific reports 2024 Oct 10;14(1):23782
Scientific reports 2024 Oct 10;14(1):23782
CD2AP promotes the progression of glioblastoma multiforme via TRIM5-mediated NF-kB signaling.
Zhang L, He J, Zhao W, Zhou Y, Li J, Li S, Zhao W, Zhang L, Tang Z, Tan G, Chen S, Zhang B, Zhang YW, Wang Z
Cell death & disease 2024 Oct 1;15(10):722
Cell death & disease 2024 Oct 1;15(10):722
Dysfunctional astrocyte glutamate uptake in the hypothalamic paraventricular nucleus contributes to visceral pain and anxiety-like behavior in mice with chronic pancreatitis.
Luo R, Hu X, Li X, Lei F, Liao P, Yi L, Zhang X, Zhou B, Jiang R
Glia 2024 Nov;72(11):2022-2037
Glia 2024 Nov;72(11):2022-2037
S-(N,N-diethyldithiocarbamoyl)-N-acetyl-l-cysteine for the treatment of non-small cell lung cancer through regulating NF-κB signalling pathway without neurotoxicity.
Lv H, Yang H, Duan Y, Yan C, Li G, Zhao G, Sun F, Feng Y, Li Y, Fu Y, Li Y, Zhao Z, Jia X
Journal of drug targeting 2024 Nov;32(9):1111-1124
Journal of drug targeting 2024 Nov;32(9):1111-1124
The Neuroprotective Mechanisms of PPAR-γ: Inhibition of Microglia-Mediated Neuroinflammation and Oxidative Stress in a Neonatal Mouse Model of Hypoxic-Ischemic White Matter Injury.
Fang M, Yu Q, Ou J, Lou J, Zhu J, Lin Z
CNS neuroscience & therapeutics 2024 Nov;30(11):e70081
CNS neuroscience & therapeutics 2024 Nov;30(11):e70081
Neonatal hypoxia-ischemia alters the events governing the hippocampal critical period of postnatal synaptic plasticity leading to deficits in working memory in mice.
Parmar P, Spahic H, Lechner C, St Pierre M, Carlin K, Nugent M, Chavez-Valdez R
Neurobiology of disease 2024 Nov;202:106722
Neurobiology of disease 2024 Nov;202:106722
Panobinostat Attenuates Experimental Autoimmune Encephalomyelitis in Mice via Suppressing Oxidative Stress-Related Neuroinflammation and Mitochondrial Dysfunction.
Shen Y, Zhao J, Yang R, Yang H, Guo M, Ji B, Du G, Li L
International journal of molecular sciences 2024 Nov 9;25(22)
International journal of molecular sciences 2024 Nov 9;25(22)
Reactive astrocytes promote tumor progression by up-regulating tumor protocadherin 1 expression in lung cancer brain metastasis.
Tang M, Liang K, Duan W, Xia S, Shi D, Li E, Liu W, Wang Q
Biochemical and biophysical research communications 2024 Nov 5;732:150431
Biochemical and biophysical research communications 2024 Nov 5;732:150431
Neutrophil-Mimetic Upconversion Photosynthetic Nanosystem Derived from Microalgae for Targeted Treatment of Thromboembolic Stroke.
Quan X, Liu C, Chen J, Li Y, Yuan Z, Zheng Y, Mok GSP, Wang R, Zhao Y
ACS nano 2024 Nov 5;18(44):30307-30320
ACS nano 2024 Nov 5;18(44):30307-30320
Probiotics alleviate chronic ethanol exposure-induced anxiety-like behavior and hippocampal neuroinflammation in male mice through gut microbiota-derived extracellular vesicles.
Pei J, Zhang C, Zhang Q, Yu H, Yuan H, Guo Y, Shen H, Liu H, Wang C, Meng F, Yu C, Tie J, Chen X, Wu X, Zhang G, Wang X
Journal of nanobiotechnology 2024 Nov 22;22(1):730
Journal of nanobiotechnology 2024 Nov 22;22(1):730
DHA and EPA alleviate depressive-like behaviors in chronic sleep-deprived mice: Involvement of iron metabolism, oligodendrocyte-lipids peroxidation and the LCN2-NLRP3 signaling axis.
Chen L, Yang Y, Zhang N, Che H, Wang Z, Han J, Wen M
Free radical biology & medicine 2024 Nov 20;225:654-664
Free radical biology & medicine 2024 Nov 20;225:654-664
Dexmedetomidine Attenuates Neuroinflammation-Mediated Hippocampal Neurogenesis Impairment in Sepsis-Associated Encephalopathy Mice through Central α2A-Adrenoceptor.
Zhang X, Feng Y, Zhong Y, Ding R, Guo Y, Jiang F, Xing Y, Shi H, Bao H, Si Y
ACS chemical neuroscience 2024 Nov 20;15(22):4185-4201
ACS chemical neuroscience 2024 Nov 20;15(22):4185-4201
The P38MAPK Pathway Mediates the Destruction of the Blood-Brain Barrier in Anti-NMDAR Encephalitis Mice.
Lao D, Gong Z, Li T, Mo X, Huang W
Neurochemical research 2024 Nov 19;50(1):21
Neurochemical research 2024 Nov 19;50(1):21
Lentivirus-mediated Knockdown of Ski Improves Neurological Function After Spinal Cord Injury in Rats.
Wang ZQ, Ran R, Ma CW, Zhao GH, Zhou KS, Zhang HH
Neurochemical research 2024 Nov 16;50(1):15
Neurochemical research 2024 Nov 16;50(1):15
Abnormal hippocampal neurogenesis and impaired social recognition memory in two neurodevelopmental models of schizophrenia.
Dong Y, Fu C, Zhang T, Dong F, Zhu X, Jiang Y, Hu L, Pan L, Li J, Zhang X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Nov 15;38(21):e70138
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Nov 15;38(21):e70138
Jiawei Bai-Hu-decoction ameliorated heat stroke-induced brain injury by inhibiting TLR4/NF-κB signal and mitophagy of glial cell.
Lin YK, Hong YL, Liu CY, Lin WQ, Liang K, Deng SQ, Zhang XJ, Zeng JX, Wang S
Journal of ethnopharmacology 2024 Nov 15;334:118571
Journal of ethnopharmacology 2024 Nov 15;334:118571
Exercise rescues cognitive impairment through inhibiting the fibrinogen neuroinflammative pathway in diabetes.
Lu D, Qu C, Fang M, Zhang J
Metabolic brain disease 2024 Nov 13;40(1):2
Metabolic brain disease 2024 Nov 13;40(1):2
Exploring miR-21 as a key regulator in two distinct approaches of bone marrow stromal cells differentiation into Schwann-like cells.
Liu YM, Wang HY, Wei CH, Li JP, Wang Y, Ma WZ, Jia H
Synapse (New York, N.Y.) 2024 May;78(3):e22293
Synapse (New York, N.Y.) 2024 May;78(3):e22293
Construction of functional neural network tissue combining CBD-NT3-modified linear-ordered collagen scaffold and TrkC-modified iPSC-derived neural stem cells for spinal cord injury repair.
Wu Z, Zhou Y, Hou X, Liu W, Yin W, Wang L, Cao Y, Jiang Z, Guo Y, Chen Q, Xie W, Wang Z, Shi N, Liu Y, Gao X, Luo L, Dai J, Ren C, Jiang X
Bioactive materials 2024 May;35:242-258
Bioactive materials 2024 May;35:242-258
Inhibition of ADORA3 promotes microglial phagocytosis and alleviates chronic ischemic white matter injury.
Xu Y, Tang L, Zhou C, Sun L, Hu Y, Zhang Z, Xia S, Bao X, Yang H, Xu Y
CNS neuroscience & therapeutics 2024 May;30(5):e14742
CNS neuroscience & therapeutics 2024 May;30(5):e14742
Glucose-modified BSA/procyanidin C1 NPs penetrate the blood-brain barrier and alleviate neuroinflammation in Alzheimer's disease models.
Duan L, Hao Z, Ji R, Li X, Wang H, Su Y, Guan F, Ma S
International journal of biological macromolecules 2024 May;268(Pt 1):131739
International journal of biological macromolecules 2024 May;268(Pt 1):131739
MG53/GMs/HA-Dex neural scaffold promotes the functional recovery of spinal cord injury by alleviating neuroinflammation.
Li X, Ji R, Duan L, Hao Z, Su Y, Wang H, Guan F, Ma S
International journal of biological macromolecules 2024 May;267(Pt 2):131520
International journal of biological macromolecules 2024 May;267(Pt 2):131520
Conditioned medium from human dental pulp stem cells treats spinal cord injury by inhibiting microglial pyroptosis.
Liu T, Ma Z, Liu L, Pei Y, Wu Q, Xu S, Liu Y, Ding N, Guan Y, Zhang Y, Chen X
Neural regeneration research 2024 May;19(5):1105-1111
Neural regeneration research 2024 May;19(5):1105-1111
Cerebral furin deficiency causes hydrocephalus in mice.
Xie S, Xie X, Tang J, Luo B, Chen J, Wen Q, Zhou J, Chen G
Genes & diseases 2024 May;11(3):101009
Genes & diseases 2024 May;11(3):101009
The Traf2 and NcK interacting kinase inhibitor NCB-0846 suppresses seizure activity involving the decrease of GRIA1.
Wang M, Gu Y, Li Q, Feng B, Lv X, Zhang H, Kong Q, Dong Z, Tian X, Zhang Y
Genes & diseases 2024 May;11(3):100997
Genes & diseases 2024 May;11(3):100997
Effect of Myelin Debris on the Phenotypic Transformation of Astrocytes after Spinal Cord Injury in Rats.
Lv J, Yu H, Shan F, Ye J, Li A, Jing J, Zheng M, Tian D
Neuroscience 2024 May 24;547:1-16
Neuroscience 2024 May 24;547:1-16
Pin1 Downregulation Is Involved in Excess Retinoic Acid-Induced Failure of Neural Tube Closure.
Chen Y, Pang J, Ye L, Zhang Z, Kang J, Qiu Z, Lin N, Liu H
International journal of molecular sciences 2024 May 21;25(11)
International journal of molecular sciences 2024 May 21;25(11)
Effect of total flavonoids of Dracocephalum moldavica L. On neuroinflammation in Alzheimer's disease model amyloid-β (Aβ1-42)-peptide-induced astrocyte activation.
Ren W, Yan XS, Fan JC, Huo DS, Wang XX, Jia JX, Yang ZJ
Journal of toxicology and environmental health. Part A 2024 May 18;87(10):436-447
Journal of toxicology and environmental health. Part A 2024 May 18;87(10):436-447
A robust vessel-labeling pipeline with high tissue clearing compatibility for 3D mapping of vascular networks.
Deng Y, Zhu J, Liu X, Dai J, Yu T, Zhu D
iScience 2024 May 17;27(5):109730
iScience 2024 May 17;27(5):109730
Inhibition of sugar-binding activity of Galectins-8 by thiogalactoside (TDG) attenuates secondary brain damage and improves long-term prognosis following intracerebral hemorrhage.
Song J, Bai H, Chen S, Xing Y, Lou J
Heliyon 2024 May 15;10(9):e30422
Heliyon 2024 May 15;10(9):e30422
Melatonin MT1 receptors regulate the Sirt1/Nrf2/Ho-1/Gpx4 pathway to prevent α-synuclein-induced ferroptosis in Parkinson's disease.
Lv QK, Tao KX, Yao XY, Pang MZ, Cao BE, Liu CF, Wang F
Journal of pineal research 2024 Mar;76(2):e12948
Journal of pineal research 2024 Mar;76(2):e12948
A New Approach for Exploring Reperfusion Brain Damage in Hypoxic Ischemic Encephalopathy.
Zhang T, Zhang Z, Geng J, Lin K, Lin X, Jiao M, Zhu J, Guo X, Lin Z
Molecular neurobiology 2024 Mar;61(3):1417-1432
Molecular neurobiology 2024 Mar;61(3):1417-1432
Inhibiting the NLRP3 Inflammasome with MCC950 Alleviates Neurological Impairment in the Brain of EAE Mice.
Hou B, Yin J, Liu S, Guo J, Zhang B, Zhang Z, Yang L, Tan X, Long Y, Feng S, Zhou J, Wu Y, Wang X, Han S, Wang Z, He X
Molecular neurobiology 2024 Mar;61(3):1318-1330
Molecular neurobiology 2024 Mar;61(3):1318-1330
Dl-3-n-Butylphthalide Alleviates Secondary Brain Damage and Improves Working Memory After Stroke in Cynomolgus Monkeys.
Jiang Z, Wei J, Liang J, Huang W, Ouyang F, Chen C, Li P, Cao S, Cai Y, Li J, Huang B, Zeng J, Chen Y
Stroke 2024 Mar;55(3):725-734
Stroke 2024 Mar;55(3):725-734
Rasd1 is involved in white matter injury through neuron-oligodendrocyte communication after subarachnoid hemorrhage.
Fu W, Che X, Tan J, Cui S, Ma Y, Xu D, Long H, Yang X, Wen T, He Z
CNS neuroscience & therapeutics 2024 Mar;30(3):e14452
CNS neuroscience & therapeutics 2024 Mar;30(3):e14452
Baicalein ameliorates cognitive impairment of vascular dementia rats via suppressing neuroinflammation and regulating intestinal microbiota.
Song J, Li M, Kang N, Jin W, Xiao Y, Li Z, Qi Q, Zhang J, Duan Y, Feng X, Lv P
Brain research bulletin 2024 Mar;208:110888
Brain research bulletin 2024 Mar;208:110888
Oxidative stress and mitochondrial dysfunction in brain of vinclozolin exposed animals.
Interdonato L, Marino Y, D'Amico R, Impellizzeri D, Cordaro M, Siracusa R, Gugliandolo E, Franco GA, Fusco R, Cuzzocrea S, Di Paola R
Neurochemistry international 2024 Mar;174:105681
Neurochemistry international 2024 Mar;174:105681
Panax notoginseng saponins stimulates the differentiation and neurite development of C17.2 neural stem cells against OGD/R injuries via mTOR signaling.
Gao J, Yao M, Zhang Y, Jiang Y, Liu J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Mar;172:116260
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Mar;172:116260
Hypoxia inducible factor-1α regulates microglial innate immune memory and the pathology of Parkinson's disease.
Dong H, Zhang X, Duan Y, He Y, Zhao J, Wang Z, Wang J, Li Q, Fan G, Liu Z, Shen C, Zhang Y, Yu M, Fei J, Huang F
Journal of neuroinflammation 2024 Mar 30;21(1):80
Journal of neuroinflammation 2024 Mar 30;21(1):80
Activation of astrocytes by ANXA2-derived extracellular vesicles from lung cancer cells affects aggressiveness, immunotherapy response and microenvironment of lung cancer.
He M, Xie G, Shen F, Li X
Heliyon 2024 Mar 30;10(6):e27729
Heliyon 2024 Mar 30;10(6):e27729
A novel microglia-targeting strategy based on nanoparticle-mediated delivery of miR-26a-5p for long-lasting analgesia in chronic pain.
Lu Y, Liu S, Wang P, Guo X, Qin Z, Hou H, Tao T
Journal of nanobiotechnology 2024 Mar 23;22(1):128
Journal of nanobiotechnology 2024 Mar 23;22(1):128
Gastrodia elata polysaccharide alleviates Parkinson's disease via inhibiting apoptotic and inflammatory signaling pathways and modulating the gut microbiota.
Gan QX, Peng MY, Wei HB, Chen LL, Chen XY, Li ZH, An GQ, Ma YT
Food & function 2024 Mar 18;15(6):2920-2938
Food & function 2024 Mar 18;15(6):2920-2938
Human-induced pluripotent stem cell-derived neural stem/progenitor cell ex vivo gene therapy with synaptic organizer CPTX for spinal cord injury.
Saijo Y, Nagoshi N, Kawai M, Kitagawa T, Suematsu Y, Ozaki M, Shinozaki M, Kohyama J, Shibata S, Takeuchi K, Nakamura M, Yuzaki M, Okano H
Stem cell reports 2024 Mar 12;19(3):383-398
Stem cell reports 2024 Mar 12;19(3):383-398
Repeated antibiotic drug treatment negatively affects memory function and glutamatergic nervous system of the hippocampus in mice.
Takahashi K, Kurokawa K, Miyagawa K, Mochida-Saito A, Takeda H, Tsuji M
Neuroscience letters 2024 Mar 10;825:137711
Neuroscience letters 2024 Mar 10;825:137711
Rab11 regulates autophagy at dendritic spines in an mTOR- and NMDA-dependent manner.
Janusz-Kaminska A, Brzozowska A, Tempes A, Urbanska M, Blazejczyk M, Miłek J, Kuzniewska B, Zeng J, Wesławski J, Kisielewska K, Bassell GJ, Jaworski J
Molecular biology of the cell 2024 Mar 1;35(3):ar43
Molecular biology of the cell 2024 Mar 1;35(3):ar43
Periplaneta Americana (L.) extract activates the ERK/CREB/BDNF pathway to promote post-stroke neuroregeneration and recovery of neurological functions in rats.
Rao J, Li H, Zhang H, Xiang X, Ding X, Li L, Geng F, Qi H
Journal of ethnopharmacology 2024 Mar 1;321:117400
Journal of ethnopharmacology 2024 Mar 1;321:117400
Neuronal small extracellular vesicles carrying miR-181c-5p contribute to the pathogenesis of epilepsy by regulating the protein kinase C-δ/glutamate transporter-1 axis in astrocytes.
Ma L, Wu Q, You Y, Zhang P, Tan D, Liang M, Huang Y, Gao Y, Ban Y, Chen Y, Yuan J
Glia 2024 Jun;72(6):1082-1095
Glia 2024 Jun;72(6):1082-1095
Injectable ultrasonic sensor for wireless monitoring of intracranial signals.
Tang H, Yang Y, Liu Z, Li W, Zhang Y, Huang Y, Kang T, Yu Y, Li N, Tian Y, Liu X, Cheng Y, Yin Z, Jiang X, Chen X, Zang J
Nature 2024 Jun;630(8015):84-90
Nature 2024 Jun;630(8015):84-90
PHPB ameliorates memory deficits and reduces oxidative injury in Alzheimer's disease mouse model by activating Nrf2 signaling pathway.
Shang NY, Huang LJ, Lan JQ, Kang YY, Tang JS, Wang HY, Li XN, Sun Z, Chen QY, Liu MY, Wen ZP, Feng XH, Wu L, Peng Y
Acta pharmacologica Sinica 2024 Jun;45(6):1142-1159
Acta pharmacologica Sinica 2024 Jun;45(6):1142-1159
Hippocampal mitophagy contributes to spatial memory via maintaining neurogenesis during the development of mice.
Xu L, Saeed S, Ma X, Cen X, Sun Y, Tian Y, Zhang X, Zhang D, Tang A, Zhou H, Lai J, Xia H, Hu S
CNS neuroscience & therapeutics 2024 Jun;30(6):e14800
CNS neuroscience & therapeutics 2024 Jun;30(6):e14800
White matter hyperintensities and the surrounding normal appearing white matter are associated with water channel disruption in the oldest old.
Silbert LC, Roese NE, Krajbich V, Hurworth J, Lahna D, Schwartz DL, Dodge HH, Woltjer RL
Alzheimer's & dementia : the journal of the Alzheimer's Association 2024 Jun;20(6):3839-3851
Alzheimer's & dementia : the journal of the Alzheimer's Association 2024 Jun;20(6):3839-3851
Citrobacter rodentium infection impairs dopamine metabolism and exacerbates the pathology of Parkinson's disease in mice.
He Y, Zhao J, Ma Y, Yan X, Duan Y, Zhang X, Dong H, Fang R, Zhang Y, Li Q, Yang P, Yu M, Fei J, Huang F
Journal of neuroinflammation 2024 Jun 7;21(1):153
Journal of neuroinflammation 2024 Jun 7;21(1):153
Pongamol Alleviates Neuroinflammation and Promotes Autophagy in Alzheimer's Disease by Regulating the Akt/mTOR Signaling Pathway.
Hu K, Wu S, Xu J, Zhang Y, Zhang Y, Wu X, Miao J, Yao Y, Zhu S, Chen G, Ren J
Journal of agricultural and food chemistry 2024 Jun 6;
Journal of agricultural and food chemistry 2024 Jun 6;
Baricitinib ameliorates inflammatory and neuropathic pain in collagen antibody-induced arthritis mice by modulating the IL-6/JAK/STAT3 pathway and CSF-1 expression in dorsal root ganglion neurons.
Makabe K, Okada H, Tachibana N, Ishikura H, Ito N, Tanaka M, Chijimatsu R, Terashima A, Yano F, Asaka M, Yanagihara D, Taketomi S, Matsumoto T, Tanaka S, Omata Y, Saito T
Arthritis research & therapy 2024 Jun 15;26(1):121
Arthritis research & therapy 2024 Jun 15;26(1):121
Ginsenoside Rd enhances blood-brain barrier integrity after cerebral ischemia/reperfusion by alleviating endothelial cells ferroptosis via activation of NRG1/ErbB4-mediated PI3K/Akt/mTOR signaling pathway.
Hu S, Fei Y, Jin C, Yao J, Ding H, Wang J, Liu C
Neuropharmacology 2024 Jun 15;251:109929
Neuropharmacology 2024 Jun 15;251:109929
Codonopsis pilosula water extract delays D-galactose-induced aging of the brain in mice by activating autophagy and regulating metabolism.
Wang X, Kang J, Li X, Wu P, Huang Y, Duan Y, Feng J, Wang J
Journal of ethnopharmacology 2024 Jun 12;327:118016
Journal of ethnopharmacology 2024 Jun 12;327:118016
A probe for NIR-II imaging and multimodal analysis of early Alzheimer's disease by targeting CTGF.
Lu C, Meng C, Li Y, Yuan J, Ren X, Gao L, Su D, Cao K, Cui M, Yuan Q, Gao X
Nature communications 2024 Jun 12;15(1):5000
Nature communications 2024 Jun 12;15(1):5000
Psychobiotics Lactiplantibacillus plantarum JYLP-326: Antidepressant-like effects on CUMS-induced depressed mouse model and alleviation of gut microbiota dysbiosis.
Zhu R, Zhao X, Wu H, Zeng X, Wei J, Chen T
Journal of affective disorders 2024 Jun 1;354:752-764
Journal of affective disorders 2024 Jun 1;354:752-764
The oxytocin receptor is essential for the protective effect of pair housing on post-stroke depression in mice.
Jiang ST, Lian SY, Sun YH, Pan MB, Wang B, Wang H, Hua J, Wang YC, Wang QL, Dong YF
Experimental gerontology 2024 Jun 1;190:112432
Experimental gerontology 2024 Jun 1;190:112432
P2Y6 Receptor Activation Aggravates NLRP3-dependent Microglial Pyroptosis via Downregulation of the PI3K/AKT Pathway in a Mouse Model of Intracerebral Hemorrhage.
Li Y, Tu H, Zhang S, Ding Z, Wu G, Piao J, Lv D, Hu L, Li F, Wang Q
Molecular neurobiology 2024 Jul;61(7):4259-4277
Molecular neurobiology 2024 Jul;61(7):4259-4277
A disulfiram derivative against lung cancer via the Notch signaling pathway without neurotoxicity and hepatotoxicity.
Lv H, Yang H, Duan Y, Sha H, Zhao Z
Naunyn-Schmiedeberg's archives of pharmacology 2024 Jul;397(7):4747-4760
Naunyn-Schmiedeberg's archives of pharmacology 2024 Jul;397(7):4747-4760
NDC80/HEC1 promotes macrophage polarization and predicts glioma prognosis via single-cell RNA-seq and in vitro experiment.
Ye W, Liang X, Chen G, Chen Q, Zhang H, Zhang N, Huang Y, Cheng Q, Chen X
CNS neuroscience & therapeutics 2024 Jul;30(7):e14850
CNS neuroscience & therapeutics 2024 Jul;30(7):e14850
Targeting Phactr4 to rescue chronic stress-induced depression-like behavior in rats via regulating neuroinflammation and neuroplasticity.
Li Y, Chen X, Lan T, Wang W, Wang C, Chang M, Yu Z, Yu S
International journal of biological macromolecules 2024 Jul;273(Pt 2):132854
International journal of biological macromolecules 2024 Jul;273(Pt 2):132854
Astaxanthin alleviates fibromyalgia pain and depression via NLRP3 inflammasome inhibition.
Zhao L, Tao X, Wang K, Song Y, Zhang B, Yang L, Wang Z
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jul;176:116856
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jul;176:116856
Zein-Based Triple-Drug Nanoparticles to Promote Anti-Inflammatory Responses for Nerve Regeneration after Spinal Cord Injury.
Wang J, Lin Y, Li C, Lei F, Luo H, Jing P, Fu Y, Zhang Z, Wang C, Liu Z, Jiang J, Zhou M, Du X, Liu Z, Zhou X, Sun X, Zhong Z
Advanced healthcare materials 2024 Jul;13(18):e2304261
Advanced healthcare materials 2024 Jul;13(18):e2304261
Brain Metastasis from EGFR-Mutated Non-Small Cell Lung Cancer: Secretion of IL11 from Astrocytes Up-Regulates PDL1 and Promotes Immune Escape.
Tang M, Xu M, Wang J, Liu Y, Liang K, Jin Y, Duan W, Xia S, Li G, Chu H, Liu W, Wang Q
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jul;11(26):e2306348
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jul;11(26):e2306348
Acid Neutralization by Composite Lysine Nanoparticles for Spinal Cord Injury Recovery through Mitigating Mitochondrial Dysfunction.
Wang Q, Ge L, Guo J, Zhang H, Chen T, Lian F, Li L, Xu Y, Xu J, Chen N, Zhang Y, Ruan Z, Xiao J, Zhang H, Yang L
ACS biomaterials science & engineering 2024 Jul 8;10(7):4480-4495
ACS biomaterials science & engineering 2024 Jul 8;10(7):4480-4495
Lactylation of histone by BRD4 regulates astrocyte polarization after experimental subarachnoid hemorrhage.
Zhang F, Zhou J, Lu P, Zhang X, Yang L, Wu J, Zhang L, Zhang L, Pang J, Xie H, Xie B, Jiang Y, Peng J
Journal of neuroinflammation 2024 Jul 30;21(1):186
Journal of neuroinflammation 2024 Jul 30;21(1):186
Local Delivery of Dual Stem Cell-Derived Exosomes Using an Electrospun Nanofibrous Platform for the Treatment of Traumatic Brain Injury.
Li J, Li X, Li X, Liang Z, Wang Z, Shahzad KA, Xu M, Tan F
ACS applied materials & interfaces 2024 Jul 24;16(29):37497-37512
ACS applied materials & interfaces 2024 Jul 24;16(29):37497-37512
Intestinal microbiota imbalance resulted by anti-Toxoplasma gondii immune responses aggravate gut and brain injury.
Chen J, Zhang C, Yang Z, Wu W, Zou W, Xin Z, Zheng S, Liu R, Yang L, Peng H
Parasites & vectors 2024 Jul 2;17(1):284
Parasites & vectors 2024 Jul 2;17(1):284
Selenoprotein W modulates tau homeostasis in an Alzheimer's disease mouse model.
Ren B, Situ J, Huang X, Tan Q, Xiao S, Li N, Tian J, Du X, Ni J, Liu Q
Communications biology 2024 Jul 17;7(1):872
Communications biology 2024 Jul 17;7(1):872
Multienzyme Active Nanozyme for Efficient Sepsis Therapy through Modulating Immune and Inflammation Inhibition.
Xin Q, Zhang S, Sun S, Song N, Zhe Y, Tian F, Zhang S, Guo M, Zhang XD, Zhang J, Wang H, Zhang R
ACS applied materials & interfaces 2024 Jul 17;16(28):36047-36062
ACS applied materials & interfaces 2024 Jul 17;16(28):36047-36062
TRAF6 promotes spinal microglial M1 polarization to aggravate neuropathic pain by activating the c-JUN/NF-kB signaling pathway.
Zhao Y, Li T, Zhang L, Yang J, Zhao F, Wang Y, Ouyang Y, Liu J
Cell biology and toxicology 2024 Jul 12;40(1):54
Cell biology and toxicology 2024 Jul 12;40(1):54
Hypersensitivity of the vimentin cytoskeleton to net-charge states and Coulomb repulsion.
Unger BA, Wu CY, Choi AA, He C, Xu K
bioRxiv : the preprint server for biology 2024 Jul 11;
bioRxiv : the preprint server for biology 2024 Jul 11;
Disorder of neuroplasticity aggravates cognitive impairment via neuroinflammation associated with intestinal flora dysbiosis in chronic heart failure.
Chen J, Wei X, Wu X, Zhang Q, Xia G, Xia H, Shang H, Lin S
Aging 2024 Jul 1;16(13):10882-10904
Aging 2024 Jul 1;16(13):10882-10904
Mitochondria-targeted cerium vanadate nanozyme suppressed hypoxia-ischemia injury in neonatal mice via intranasal administration.
Jiang Z, Wang W, Zhao Y, Li T, Xin D, Gai C, Liu D, Wang Z
Journal of controlled release : official journal of the Controlled Release Society 2024 Jan;365:1074-1088
Journal of controlled release : official journal of the Controlled Release Society 2024 Jan;365:1074-1088
Melatonin exerts neuroprotective effects in mice with spinal cord injury by activating the Nrf2/Keap1 signaling pathway via the MT2 receptor.
Yan L, Han X, Zhang M, Kou H, Liu H, Cheng T
Experimental and therapeutic medicine 2024 Jan;27(1):37
Experimental and therapeutic medicine 2024 Jan;27(1):37
BAFF deficiency aggravated optic nerve crush-induced retinal ganglion cells damage by regulating apoptosis and neuroinflammation via NF-κB-IκBα signaling.
Lin J, Deng W, Liao J, Ke D, Cui L, Zhong H, Huang K, Jiang L, Chen Q, Xu F, Tang F
International immunopharmacology 2024 Jan 5;126:111287
International immunopharmacology 2024 Jan 5;126:111287
Based on spinal central sensitization creating analgesic screening approach to excavate anti-neuropathic pain ingredients of Corydalis yanhusuo W.T.Wang.
Zhou MY, Yao CH, Yang YJ, Li X, Yang J, Liu JH, Yu BY, Dai WL
Journal of ethnopharmacology 2024 Jan 30;319(Pt 1):117084
Journal of ethnopharmacology 2024 Jan 30;319(Pt 1):117084
MiR-31-5p regulates the neuroinflammatory response via TRAF6 in neuropathic pain.
Liu Y, Wang L, Zhou C, Yuan Y, Fang B, Lu K, Xu F, Chen L, Huang L
Biology direct 2024 Jan 24;19(1):10
Biology direct 2024 Jan 24;19(1):10
hBcl2 overexpression in BMSCs enhances resistance to myelin debris-induced apoptosis and facilitates neuroprotection after spinal cord injury in rats.
Tian D, You X, Ye J, Chen G, Yu H, Lv J, Shan F, Liang C, Bi Y, Jing J, Zheng M
Scientific reports 2024 Jan 21;14(1):1830
Scientific reports 2024 Jan 21;14(1):1830
BAF45D-binding to HOX genes was differentially targeted in H9-derived spinal cord neural stem cells.
Liu C, Xie Y, Chen X, Liu L, Liu C, Yin Z
Scientific reports 2024 Jan 2;14(1):29
Scientific reports 2024 Jan 2;14(1):29
Network pharmacology analysis of the active ingredients of Corydalis hendersonii Hemsl. and their effects on eliminating neuroinflammation and improving motor functions in MPTP-intoxicated mice.
Wang J, Liu QT, Shen DY, Bai JP, Hu Y, Huang Q, Yu HJ, He NN, Qin XY, Lan R
Journal of ethnopharmacology 2024 Jan 10;318(Pt B):117009
Journal of ethnopharmacology 2024 Jan 10;318(Pt B):117009
Illustrate the distribution and metabolic regulatory effects of pterostilbene in cerebral ischemia-reperfusion rat brain by mass spectrometry imaging and spatial metabolomics.
Ban W, Jiang X, Lv L, Jiao Y, Huang J, Yang Z, You Y
Talanta 2024 Jan 1;266(Pt 2):125060
Talanta 2024 Jan 1;266(Pt 2):125060
TGN-020 Alleviate Inflammation and Apoptosis After Cerebral Ischemia-Reperfusion Injury in Mice Through Glymphatic and ERK1/2 Signaling Pathway.
Li X, Xie Z, Zhou Q, Tan X, Meng W, Pang Y, Huang L, Ding Z, Hu Y, Li R, Huang G, Li H
Molecular neurobiology 2024 Feb;61(2):1175-1186
Molecular neurobiology 2024 Feb;61(2):1175-1186
Caffeic acid alleviates cerebral ischemic injury in rats by resisting ferroptosis via Nrf2 signaling pathway.
Li XN, Shang NY, Kang YY, Sheng N, Lan JQ, Tang JS, Wu L, Zhang JL, Peng Y
Acta pharmacologica Sinica 2024 Feb;45(2):248-267
Acta pharmacologica Sinica 2024 Feb;45(2):248-267
Erythrocyte membrane-coated nanocarriers modified by TGN for Alzheimer's disease.
Gu J, Yan C, Yin S, Wu H, Liu C, Xue A, Lei X, Zhang N, Geng F
Journal of controlled release : official journal of the Controlled Release Society 2024 Feb;366:448-459
Journal of controlled release : official journal of the Controlled Release Society 2024 Feb;366:448-459
Targeted transplantation of engineered mitochondrial compound promotes functional recovery after spinal cord injury by enhancing macrophage phagocytosis.
Xu J, Shi C, Yuan F, Ding Y, Xie Y, Liu Y, Zhu F, Lu H, Duan C, Hu J, Jiang L
Bioactive materials 2024 Feb;32:427-444
Bioactive materials 2024 Feb;32:427-444
Sustainable inflammatory activation following spinal cord injury is driven by thrombin-mediated dynamic expression of astrocytic chemokines.
He B, Niu L, Li S, Li H, Hou Y, Li A, Zhang X, Hao H, Song H, Cai R, Zhou Y, Wang Y, Wang Y
Brain, behavior, and immunity 2024 Feb;116:85-100
Brain, behavior, and immunity 2024 Feb;116:85-100
Inhibition of spinal Rac1 attenuates chronic inflammatory pain by regulating the activation of astrocytes.
Wan Y, Zhou J, Zhang P, Lin X, Li H
Cellular signalling 2024 Feb;114:110972
Cellular signalling 2024 Feb;114:110972
Chronic Spinal Cord Injury Regeneration with Combined Therapy Comprising Neural Stem/Progenitor Cell Transplantation, Rehabilitation, and Semaphorin 3A Inhibitor.
Yoshida T, Tashiro S, Nagoshi N, Shinozaki M, Shibata T, Inoue M, Ogawa S, Shibata S, Tsuji T, Okano H, Nakamura M
eNeuro 2024 Feb;11(2)
eNeuro 2024 Feb;11(2)
Sulbactam protects neurons against double neurotoxicity of amyloid beta and glutamate load by upregulating glial glutamate transporter 1.
Li L, Li W, Jiang W, Xu R
Cell death discovery 2024 Feb 6;10(1):64
Cell death discovery 2024 Feb 6;10(1):64
Bicarbonate signalling via G protein-coupled receptor regulates ischaemia-reperfusion injury.
Jo-Watanabe A, Inaba T, Osada T, Hashimoto R, Nishizawa T, Okuno T, Ihara S, Touhara K, Hattori N, Oh-Hora M, Nureki O, Yokomizo T
Nature communications 2024 Feb 27;15(1):1530
Nature communications 2024 Feb 27;15(1):1530
A Comparative Biochemical and Pathological Evaluation of Brain Samples from Knock-In Murine Models of Gaucher Disease.
Furderer ML, Berhe B, Chen TC, Wincovitch S, Jiang X, Tayebi N, Sidransky E, Han TU
International journal of molecular sciences 2024 Feb 2;25(3)
International journal of molecular sciences 2024 Feb 2;25(3)
Potential Role of Bmal1 in Lipopolysaccharide-Induced Depression-Like Behavior and its Associated "Inflammatory Storm".
Xu DD, Hou ZQ, Xu YY, Liang J, Gao YJ, Zhang C, Guo F, Huang DD, Ge JF, Xia QR
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2024 Feb 2;19(1):4
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2024 Feb 2;19(1):4
Disease-Associated Neurotoxic Astrocyte Markers in Alzheimer Disease Based on Integrative Single-Nucleus RNA Sequencing.
Yu W, Li Y, Zhong F, Deng Z, Wu J, Yu W, Lü Y
Cellular and molecular neurobiology 2024 Feb 12;44(1):20
Cellular and molecular neurobiology 2024 Feb 12;44(1):20
Regulation of TAR DNA binding protein 43 (TDP-43) homeostasis by cytosolic DNA accumulation.
Yang C, Leifer C, Lammerding J, Hu F
The Journal of biological chemistry 2024 Dec;300(12):107999
The Journal of biological chemistry 2024 Dec;300(12):107999
Identification of Brain Cell Type-Specific Therapeutic Targets for Glioma From Genetics.
Gui J, Chen J, Wan K, Liu Y, Huang K, Zhu X
CNS neuroscience & therapeutics 2024 Dec;30(12):e70185
CNS neuroscience & therapeutics 2024 Dec;30(12):e70185
Interleukin-3 Modulates Macrophage Phagocytic Activity and Promotes Spinal Cord Injury Repair.
Li J, Zheng M, Ouyang F, Ye J, Huang J, Zhao Y, Wang J, Shan F, Li Z, Yu S, Yao F, Tian D, Cheng L, Jing J
CNS neuroscience & therapeutics 2024 Dec;30(12):e70181
CNS neuroscience & therapeutics 2024 Dec;30(12):e70181
Activation of the Nrf2/Keap1 signaling pathway mediates the neuroprotective effect of Perillyl alcohol against cerebral hypoxic-ischemic damage in neonatal rats.
Fang Y, Zheng Y, Gao Q, Pang M, Wu Y, Feng X, Tao X, Hu Y, Lin Z, Lin W
Redox report : communications in free radical research 2024 Dec;29(1):2394714
Redox report : communications in free radical research 2024 Dec;29(1):2394714
Gut microbiota modification by diosgenin mediates antiepileptic effects in a mouse model of epilepsy.
Li X, Li J, Ji J, Li S, Yao X, Fan H, Yao R
Journal of neurochemistry 2024 Dec;168(12):3982-4000
Journal of neurochemistry 2024 Dec;168(12):3982-4000
Ginsenoside compound K alleviates brain aging by inhibiting ferroptosis through modulation of the ASK1-MKK7-JNK signaling pathway.
Yan X, Bai X, Sun G, Duan Z, Fu R, Zeng W, Zhu C, Fan D
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156239
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156239
AD-Like Neuropsychiatric Dysfunction in a Mice Model Induced by a Combination of High-Fat Diet and Intraperitoneal Injection of Streptozotocin.
Sun H, Gao X, Niu J, Chen P, He S, Xu S, Ge J
eNeuro 2024 Dec;11(12)
eNeuro 2024 Dec;11(12)
Neuron-like lineage differentiation induced by exogenous Neurexin-1 as a potential therapeutic strategy for glioma.
Liao C, Chen Y, Peng D, Li S, Liu L, Li Q, Huang R, Huang L, Jiang T, Hu H, Li Y
Cancer letters 2024 Dec 8;611:217387
Cancer letters 2024 Dec 8;611:217387
Liu-Shen-Wan inhibits PI3K/Akt and TRPV1 signaling alleviating bone cancer pain in rats.
Zhang H, Jiang J, Chen X, Zhu F, Fu F, Chen A, Fu L, Mao D
Cancer biology & therapy 2024 Dec 31;25(1):2432098
Cancer biology & therapy 2024 Dec 31;25(1):2432098
Histological effects of combined therapy involving scar resection, decellularized scaffolds, and human iPSC-NS/PCs transplantation in chronic complete spinal cord injury.
Ito K, Shinozaki M, Hashimoto S, Saijo Y, Suematsu Y, Tanaka T, Nishi K, Yagi H, Shibata S, Kitagawa Y, Nakamura M, Okano H, Kohyama J, Nagoshi N
Scientific reports 2024 Dec 28;14(1):31500
Scientific reports 2024 Dec 28;14(1):31500
Neuroprotective effects of gypenosides on LPS-induced anxiety and depression-like behaviors.
Guo M, Pei WJ, Liu L, Chen K, Cheng Y, Piao XL
International immunopharmacology 2024 Dec 25;143(Pt 1):113367
International immunopharmacology 2024 Dec 25;143(Pt 1):113367
Evaluation of the Neuroprotective Effect of Total Glycosides of Cistanche deserticola and Investigation of Novel Brain-Targeting Natural MAO-B Inhibitors.
Zhai X, Xie W, Yaqoob MD, Zhao F, Zhu HZ, Yang SS, Wang K, Wang X, Wang HC, Wang X
ACS chemical neuroscience 2024 Dec 18;15(24):4544-4558
ACS chemical neuroscience 2024 Dec 18;15(24):4544-4558
Exploring PDE5A upregulation in bipolar disorder: insights from single-nucleus RNA sequencing of human basal ganglia.
Bai Z, Li P, Gao X, Zu G, Jiang A, Wu K, Mechawar N, Turecki G, Lehnert K, Snell RG, Zhou J, Hu J, Yan B, Chen L, Li W, Chen Y, Liu S, Zhu Y, You L
Translational psychiatry 2024 Dec 18;14(1):494
Translational psychiatry 2024 Dec 18;14(1):494
The crucial role of NR2A mediating the activation of satellite glial cells in the trigeminal ganglion contributes to orofacial inflammatory pain during TMJ inflammation.
Song QX, Zhang YY, Li YL, Liu F, Liu YJ, Li YK, Li CJ, Zhou C, Shen JF
Neuropharmacology 2024 Dec 15;261:110173
Neuropharmacology 2024 Dec 15;261:110173
TRIM24-DTNBP1-ATP7A mediated astrocyte cuproptosis in cognition and memory dysfunction caused by Y(2)O(3) NPs.
Chen Z, Liu J, Zheng M, Mo M, Hu X, Liu C, Pathak JL, Wang L, Chen L
The Science of the total environment 2024 Dec 1;954:176353
The Science of the total environment 2024 Dec 1;954:176353
Propofol Mitigates Sepsis-Induced Brain Injury by Inhibiting Ferroptosis Via Activation of the Nrf2/HO-1axis.
Zhou Y, Yang Y, Yi L, Pan M, Tang W, Duan H
Neurochemical research 2024 Aug;49(8):2131-2147
Neurochemical research 2024 Aug;49(8):2131-2147
Targeted inhibition of autophagy in hepatic stellate cells by hydroxychloroquine: An effective therapeutic approach for the treatment of liver fibrosis.
Hou LS, Zhai XP, Zhang YW, Xing JH, Li C, Zhou SY, Zhu XH, Zhang BL
Liver international : official journal of the International Association for the Study of the Liver 2024 Aug;44(8):1937-1951
Liver international : official journal of the International Association for the Study of the Liver 2024 Aug;44(8):1937-1951
Silencing CXCL16 alleviate neuroinflammation and M1 microglial polarization in mouse brain hemorrhage model and BV2 cell model through PI3K/AKT pathway.
Dingyi L, Libin H, Jifeng P, Ding Z, Yulong L, Zhangyi W, Yunong Y, Qinghua W, Feng L
Experimental brain research 2024 Aug;242(8):1917-1932
Experimental brain research 2024 Aug;242(8):1917-1932
Protective effect of melatonin against metabolic disorders and neuropsychiatric injuries in type 2 diabetes mellitus mice.
Gao X, Sun H, Wei Y, Niu J, Hao S, Sun H, Tang G, Qi C, Ge J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Aug;131:155805
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Aug;131:155805
Quercetin-loaded Human Umbilical cord Mesenchymal Stem Cell-derived sEVs for Spinal Cord Injury Recovery.
Yang C, Xu T, Lu Y, Liu J, Chen C, Wang H, Chen X
Neuroscience 2024 Aug 6;552:14-28
Neuroscience 2024 Aug 6;552:14-28
Emodin attenuates hypoxic-ischemic brain damage by inhibiting neuronal apoptosis in neonatal mice.
Guo Y, Chen Y, Zhang H, Zhang Q, Jin M, Wang S, Du X, Du Y, Xu D, Wang M, Li L, Luo L
Neuroscience 2024 Aug 30;554:83-95
Neuroscience 2024 Aug 30;554:83-95
Tetramethylpyrazine alleviates ferroptosis and promotes functional recovery in spinal cord injury by regulating GPX4/ACSL4.
Liu G, Deng B, Huo L, Fan X, Bai H, Zhao Y, Xu L, Gao F, Mu X
European journal of pharmacology 2024 Aug 15;977:176710
European journal of pharmacology 2024 Aug 15;977:176710
Fisetin Promotes Functional Recovery after Spinal Cord Injury by Inhibiting Microglia/Macrophage M1 Polarization and JAK2/STAT3 Signaling Pathway.
Ji R, Hao Z, Wang H, Su Y, Yang W, Li X, Duan L, Guan F, Ma S
Journal of agricultural and food chemistry 2024 Aug 14;72(32):17964-17976
Journal of agricultural and food chemistry 2024 Aug 14;72(32):17964-17976
Du-moxibustion ameliorates depression-like behavior and neuroinflammation in chronic unpredictable mild stress-induced mice.
Jia Z, Yu W, Li X, Dong T, Wang X, Li J, Yang J, Liu Y
Journal of affective disorders 2024 Aug 1;358:211-221
Journal of affective disorders 2024 Aug 1;358:211-221
Toll-like receptor 3 signaling drives enteric glial cells against dextran sulfate sodium-induced colitis in mice.
Zeng J, Lu QQ, Du XL, Yuan L, Yang XJ
Journal of molecular histology 2024 Apr;55(2):201-210
Journal of molecular histology 2024 Apr;55(2):201-210
MFG-E8 Alleviates Cognitive Impairments Induced by Chronic Cerebral Hypoperfusion by Phagocytosing Myelin Debris and Promoting Remyelination.
Dong X, Zhang Z, Shu X, Zhuang Z, Liu P, Liu R, Xia S, Bao X, Xu Y, Chen Y
Neuroscience bulletin 2024 Apr;40(4):483-499
Neuroscience bulletin 2024 Apr;40(4):483-499
Spinal sirtuin 2 attenuates bone cancer pain by deacetylating FoxO3a.
Yang C, Kang F, Huang X, Wu W, Hou G, Zheng K, Han M, Kan B, Zhang Z, Li J
Biochimica et biophysica acta. Molecular basis of disease 2024 Apr;1870(4):167129
Biochimica et biophysica acta. Molecular basis of disease 2024 Apr;1870(4):167129
DNMT3A promotes glioma growth and malignancy via TNF-α/NF-κB signaling pathway.
Su X, Liu J, Tu Z, Ji Q, Li J, Liu F
Translational cancer research 2024 Apr 30;13(4):1786-1806
Translational cancer research 2024 Apr 30;13(4):1786-1806
Distributional coding of associative learning in discrete populations of midbrain dopamine neurons.
Avvisati R, Kaufmann AK, Young CJ, Portlock GE, Cancemi S, Costa RP, Magill PJ, Dodson PD
Cell reports 2024 Apr 23;43(4):114080
Cell reports 2024 Apr 23;43(4):114080
Enriched Environment Inhibits Neurotoxic Reactive Astrocytes via JAK2-STAT3 to Promote Glutamatergic Synaptogenesis and Cognitive Improvement in Chronic Cerebral Hypoperfusion Rats.
Fan B, Lin J, Luo Q, Liao W, Hao C
Neurotoxicity research 2024 Apr 2;42(2):22
Neurotoxicity research 2024 Apr 2;42(2):22
Neuron-targeted liposomal coenzyme Q10 attenuates neuronal ferroptosis after subarachnoid hemorrhage by activating the ferroptosis suppressor protein 1/coenzyme Q10 system.
Peng Z, Ding YN, Yang ZM, Li XJ, Zhuang Z, Lu Y, Tang QS, Hang CH, Li W
Acta biomaterialia 2024 Apr 15;179:325-339
Acta biomaterialia 2024 Apr 15;179:325-339
Selective disruption of mTORC1 and mTORC2 in VTA astrocytes induces depression and anxiety-like behaviors in mice.
Zheng Z, Zhou H, Yang L, Zhang L, Guo M
Behavioural brain research 2024 Apr 12;463:114888
Behavioural brain research 2024 Apr 12;463:114888
KYNA Ameliorates Glutamate Toxicity of HAND by Enhancing Glutamate Uptake in A2 Astrocytes.
Chen J, Zou J, Huang P, Gao X, Lun J, Li Y, Gong Z, Cao H
International journal of molecular sciences 2024 Apr 12;25(8)
International journal of molecular sciences 2024 Apr 12;25(8)
5-HT3a receptor contributes to neuropathic pain by regulating central sensitization in a rat with brachial plexus avulsion.
Liao C, Guo J, Rui J, Gao K, Lao J, Zhou Y
Physiology & behavior 2024 Apr 1;277:114503
Physiology & behavior 2024 Apr 1;277:114503
Defective neurite elongation and branching in Nibp/Trappc9 deficient zebrafish and mice.
Hu M, Bodnar B, Zhang Y, Xie F, Li F, Li S, Zhao J, Zhao R, Gedupoori N, Mo Y, Lin L, Li X, Meng W, Yang X, Wang H, Barbe MF, Srinivasan S, Bethea JR, Mo X, Xu H, Hu W
International journal of biological sciences 2023;19(10):3226-3248
International journal of biological sciences 2023;19(10):3226-3248
Loss of RAB39B does not alter MPTP-induced Parkinson's disease-like phenotypes in mice.
Wang Z, Yang D, Jiang Y, Wang Y, Niu M, Wang C, Luo H, Xu H, Li J, Zhang YW, Zhang X
Frontiers in aging neuroscience 2023;15:1087823
Frontiers in aging neuroscience 2023;15:1087823
Development of an ultrasensitive microfluidic assay for the analysis of Glial fibrillary acidic protein (GFAP) in blood.
Fazeli B, Huss A, Gómez de San José N, Otto M, Tumani H, Halbgebauer S
Frontiers in molecular biosciences 2023;10:1175230
Frontiers in molecular biosciences 2023;10:1175230
Directed Neural Stem Cells Differentiation via Signal Communication with Ni-Zn Micromotors.
Feng Y, Gao C, Xie D, Liu L, Chen B, Liu S, Yang H, Gao Z, Wilson DA, Tu Y, Peng F
Advanced materials (Deerfield Beach, Fla.) 2023 Sep;35(35):e2301736
Advanced materials (Deerfield Beach, Fla.) 2023 Sep;35(35):e2301736
Isoflurane impairs olfaction by increasing neuronal activity in the olfactory bulb.
Fu H, Zhou J, Li S, Zhang Y, Chen Z, Yang Y, Li A, Wang D
Acta physiologica (Oxford, England) 2023 Sep;239(1):e14009
Acta physiologica (Oxford, England) 2023 Sep;239(1):e14009
5-Hydroxytryptamine: a potential therapeutic target in amyotrophic lateral sclerosis.
Jiang SS, Gong MN, Rao W, Chai W, Chen WZ, Zhang X, Nie HB, Xu RS
Neural regeneration research 2023 Sep;18(9):2047-2055
Neural regeneration research 2023 Sep;18(9):2047-2055
Biliverdin modulates the Nrf2/A20/eEF1A2 axis to alleviate cerebral ischemia-reperfusion injury by inhibiting pyroptosis.
Bai W, Huo S, Zhou G, Li J, Yang Y, Shao J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115057
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115057
Neuron-derived extracellular vesicles contain synaptic proteins, promote spine formation, activate TrkB-mediated signalling and preserve neuronal complexity.
Solana-Balaguer J, Campoy-Campos G, Martín-Flores N, Pérez-Sisqués L, Sitjà-Roqueta L, Kucukerden M, Gámez-Valero A, Coll-Manzano A, Martí E, Pérez-Navarro E, Alberch J, Soriano J, Masana M, Malagelada C
Journal of extracellular vesicles 2023 Sep;12(9):e12355
Journal of extracellular vesicles 2023 Sep;12(9):e12355
Xiangshao Decoction alleviates gastric mucosal injury through NRF2 signaling pathway and reduces neuroinflammation in gastric ulcer rats.
Gong H, Han D, Luo Z, Zhu Q, Zhu X, Liu S, Chen D
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Sep;118:154954
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Sep;118:154954
Glioma-derived small extracellular vesicles induce pericyte-phenotype transition of glioma stem cells under hypoxic conditions.
Cheng Y, Li S, Hou Y, Wan W, Wang K, Fu S, Yuan Y, Yang K, Ye X
Cellular signalling 2023 Sep;109:110754
Cellular signalling 2023 Sep;109:110754
MDM2 upregulation induces mitophagy deficiency via Mic60 ubiquitination in fetal microglial inflammation and consequently neuronal DNA damage caused by exposure to ZnO-NPs during pregnancy.
Zhang Y, Zhang Y, Lei Y, Wu J, Kang Y, Zheng S, Shao L
Journal of hazardous materials 2023 Sep 5;457:131750
Journal of hazardous materials 2023 Sep 5;457:131750
Human umbilical cord-derived mesenchymal stem cells ameliorate perioperative neurocognitive disorder by inhibiting inflammatory responses and activating BDNF/TrkB/CREB signaling pathway in aged mice.
Wei P, Jia M, Kong X, Lyu W, Feng H, Sun X, Li J, Yang JJ
Stem cell research & therapy 2023 Sep 21;14(1):263
Stem cell research & therapy 2023 Sep 21;14(1):263
Transmembrane protein 184B (TMEM184B) promotes expression of synaptic gene networks in the mouse hippocampus.
Wright EB, Larsen EG, Coloma-Roessle CM, Hart HR, Bhattacharya MRC
BMC genomics 2023 Sep 20;24(1):559
BMC genomics 2023 Sep 20;24(1):559
Long-term potentiation-based screening identifies neuronal PYGM as a synaptic plasticity regulator participating in Alzheimer's disease.
Wang T, Zhou YQ, Wang Y, Zhang L, Zhu X, Wang XY, Wang JH, Han LK, Meng J, Zhang X, Luo H, Ma QL, Wang ZX, Zhang YW
Zoological research 2023 Sep 18;44(5):867-881
Zoological research 2023 Sep 18;44(5):867-881
Protocol for fine casting, imaging, and analysis of murine vascular networks with VALID.
Zhu J, Liu X, Xu J, Liu Z, Deng Y, Dai J, Yu T, Zhu D
STAR protocols 2023 Sep 15;4(3):102441
STAR protocols 2023 Sep 15;4(3):102441
A microtubule stabilizer ameliorates protein pathogenesis and neurodegeneration in mouse models of repetitive traumatic brain injury.
Zhao X, Zeng W, Xu H, Sun Z, Hu Y, Peng B, McBride JD, Duan J, Deng J, Zhang B, Kim SJ, Zoll B, Saito T, Sasaguri H, Saido TC, Ballatore C, Yao H, Wang Z, Trojanowski JQ, Brunden KR, Lee VM, He Z
Science translational medicine 2023 Sep 13;15(713):eabo6889
Science translational medicine 2023 Sep 13;15(713):eabo6889
Long-term iTBS Improves Neural Functional Recovery by Reducing the Inflammatory Response and Inhibiting Neuronal Apoptosis Via miR-34c-5p/p53/Bax Signaling Pathway in Cerebral Ischemic Rats.
Hu S, Wang X, Yang X, Ouyang S, Pan X, Fu Y, Wu S
Neuroscience 2023 Sep 1;527:37-51
Neuroscience 2023 Sep 1;527:37-51
Alleviating symptoms of neurodegenerative disorders by astrocyte-specific overexpression of TMEM164 in mice.
Zhang L, Jia Z, Wu Q, Bai T, Wang B, Hu X, Li T, Liu X, Fu J, Chen Y, Ding X, Liu Z, Xu Z, Zhou H
Nature metabolism 2023 Oct;5(10):1787-1802
Nature metabolism 2023 Oct;5(10):1787-1802
Electroacupuncture ameliorates cardiac dysfunction in myocardial ischemia model rats: a potential role of the hypothalamic-pituitary-adrenal axis.
Kun W, Jie Z, Shuai C, Xin WU, Guoqi Z, Shengbing WU, Meiqi Z
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2023 Oct;43(5):944-954
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2023 Oct;43(5):944-954
Determinants of astrocytic pathology in stem cell models of primary tauopathies.
Fiock KL, Hook JN, Hefti MM
Acta neuropathologica communications 2023 Oct 6;11(1):161
Acta neuropathologica communications 2023 Oct 6;11(1):161
Anti-inflammatory effects of myristic acid mediated by the NF-κB pathway in lipopolysaccharide-induced BV-2 microglial cells.
Huang Q, Chen C, Zhang Z, Xue Q
Molecular omics 2023 Oct 30;19(9):726-734
Molecular omics 2023 Oct 30;19(9):726-734
Neurovascular protection of alisol A on cerebral ischemia mice through activating the AKT/GSK3β pathway.
Li H, Zhang C, Zhou Y, Deng Y, Zheng X, Xue X
Aging 2023 Oct 26;15(20):11639-11653
Aging 2023 Oct 26;15(20):11639-11653
Enteric glial cells aggravate the intestinal epithelial barrier damage by secreting S100β under high-altitude conditions.
Xie H, Zeng X, Wang W, Wang W, Han B, Tan Q, Hu Q, Liu X, Chen S, Chen J, Sun L, Chen Y, Xiao W
Molecular biomedicine 2023 Oct 2;4(1):31
Molecular biomedicine 2023 Oct 2;4(1):31
Hepatocyte growth factor pretreatment boosts functional recovery after spinal cord injury through human iPSC-derived neural stem/progenitor cell transplantation.
Suematsu Y, Nagoshi N, Shinozaki M, Kase Y, Saijo Y, Hashimoto S, Shibata T, Kajikawa K, Kamata Y, Ozaki M, Yasutake K, Shindo T, Shibata S, Matsumoto M, Nakamura M, Okano H
Inflammation and regeneration 2023 Oct 16;43(1):50
Inflammation and regeneration 2023 Oct 16;43(1):50
Enriched environment attenuates ferroptosis after cerebral ischemia/reperfusion injury by regulating iron metabolism.
Luo Q, Zheng J, Fan B, Liu J, Liao W, Zhang X
Brain research bulletin 2023 Oct 15;203:110778
Brain research bulletin 2023 Oct 15;203:110778
Attenuation of Chronic Stress-Induced Depressive-like Symptoms by Fish Oil via Alleviating Neuroinflammation and Impaired Tryptophan Metabolism in Aging Rats.
Tung TH, Lai WD, Lee HC, Su KP, Panunggal B, Huang SY
Journal of agricultural and food chemistry 2023 Oct 11;71(40):14550-14561
Journal of agricultural and food chemistry 2023 Oct 11;71(40):14550-14561
Agomir-331 Suppresses Reactive Gliosis and Neuroinflammation after Traumatic Brain Injury.
Wang JX, Xiao X, He XC, He BD, Liu CM, Teng ZQ
Cells 2023 Oct 11;12(20)
Cells 2023 Oct 11;12(20)
Aluminum exposure induces central nervous system impairment via activating NLRP3-medicated pyroptosis pathway.
Hao W, Zhu X, Liu Z, Song Y, Wu S, Lu X, Yang J, Jin C
Ecotoxicology and environmental safety 2023 Oct 1;264:115401
Ecotoxicology and environmental safety 2023 Oct 1;264:115401
Umbilical cord mesenchymal stem cell-conditioned medium inhibits microglial activation to ameliorate neuroinflammation in amyotrophic lateral sclerosis mice and cell models.
Tang J, Kang Y, Zhou Y, Chen Q, Lan J, Liu X, Peng Y
Brain research bulletin 2023 Oct 1;202:110760
Brain research bulletin 2023 Oct 1;202:110760
NCBP1 Improves Cognitive Function in Mice by Reducing Oxidative Stress, Neuronal Loss, and Glial Activation After Status Epilepticus.
Gao X, You Z, Huang C, Liu Z, Tan Z, Li J, Liu Y, Liu X, Wei F, Fan Z, Qi S, Sun J
Molecular neurobiology 2023 Nov;60(11):6676-6688
Molecular neurobiology 2023 Nov;60(11):6676-6688
Catalpol Alleviates Ischemic Stroke Through Promoting Angiogenesis and Facilitating Proliferation and Differentiation of Neural Stem Cells via the VEGF-A/KDR Pathway.
Sun S, Xu Y, Yu N, Zhang M, Wang J, Wan D, Tian Z, Zhu H
Molecular neurobiology 2023 Nov;60(11):6227-6247
Molecular neurobiology 2023 Nov;60(11):6227-6247
Gut microbiome-derived ammonia modulates stress vulnerability in the host.
Wang P, Wu PF, Wang HJ, Liao F, Wang F, Chen JG
Nature metabolism 2023 Nov;5(11):1986-2001
Nature metabolism 2023 Nov;5(11):1986-2001
Inhibition of ANXA2 activity attenuates epileptic susceptibility and GluA1 phosphorylation.
Ma L, Wu Q, Yuan J, Wang Y, Zhang P, Liu Q, Tan D, Liang M, Chen Y
CNS neuroscience & therapeutics 2023 Nov;29(11):3644-3656
CNS neuroscience & therapeutics 2023 Nov;29(11):3644-3656
Potential value of Interleukin-6 as a diagnostic biomarker in human MDD and the antidepressant effect of its receptor antagonist tocilizumab in lipopolysaccharide-challenged rats.
Xu D, Xu Y, Gao X, Yan M, Zhang C, Wu X, Xia Q, Ge J
International immunopharmacology 2023 Nov;124(Pt B):110903
International immunopharmacology 2023 Nov;124(Pt B):110903
Deferoxamine attenuates visual impairment in retinal ischemia‒reperfusion via inhibiting ferroptosis.
Wang X, Li M, Diao K, Wang Y, Chen H, Zhao Z, Li Y, Jia X, Wang H, Zheng F, Xia Z, Han L, Zhang M
Scientific reports 2023 Nov 17;13(1):20145
Scientific reports 2023 Nov 17;13(1):20145
TLR2 deficiency is beneficial at the late phase in MPTP-induced Parkinson' disease mice.
He Y, Zhao J, Dong H, Zhang X, Duan Y, Ma Y, Yu M, Fei J, Huang F
Life sciences 2023 Nov 15;333:122171
Life sciences 2023 Nov 15;333:122171
In vivo labeling and quantitative imaging of neuronal populations using MRI.
Li S, Xu X, Li C, Xu Z, Wu K, Ye Q, Zhang Y, Jiang X, Cang C, Tian C, Wen J
NeuroImage 2023 Nov 1;281:120374
NeuroImage 2023 Nov 1;281:120374
Dulaglutide Improves Gliosis and Suppresses Apoptosis/Autophagy Through the PI3K/Akt/mTOR Signaling Pathway in Vascular Dementia Rats.
Guan T, Xiao Y, Xie X, Meng N, Qi Q, Xu J, Jiang X, Zhang Z, Teng Z, Lv P
Neurochemical research 2023 May;48(5):1561-1579
Neurochemical research 2023 May;48(5):1561-1579
IL1RAP Knockdown in LPS-Stimulated Normal Human Astrocytes Suppresses LPS-Induced Reactive Astrogliosis and Promotes Neuronal Cell Proliferation.
Zhou J, Xiang W, Zhang K, Zhao Q, Xu Z, Li Z
Neurochemical research 2023 May;48(5):1468-1479
Neurochemical research 2023 May;48(5):1468-1479
miR-26a-5p alleviates CFA-induced chronic inflammatory hyperalgesia through Wnt5a/CaMKII/NFAT signaling in mice.
Lu Y, Liu M, Guo X, Wang P, Zeng F, Wang H, Tang J, Qin Z, Tao T
CNS neuroscience & therapeutics 2023 May;29(5):1254-1271
CNS neuroscience & therapeutics 2023 May;29(5):1254-1271
Increased level of RAB39B leads to neuronal dysfunction and behavioural changes in mice.
Wang Z, Niu M, Zheng N, Meng J, Jiang Y, Yang D, Yao P, Yao T, Luo H, Xu H, Ge Y, Zhang YW, Zhang X
Journal of cellular and molecular medicine 2023 May;27(9):1214-1226
Journal of cellular and molecular medicine 2023 May;27(9):1214-1226
Spinal astrocytic MeCP2 regulates Kir4.1 for the maintenance of chronic hyperalgesia in neuropathic pain.
Ou M, Chen Y, Liu J, Zhang D, Yang Y, Shen J, Miao C, Tang SJ, Liu X, Mulkey DK, Zhu T, Zhou C
Progress in neurobiology 2023 May;224:102436
Progress in neurobiology 2023 May;224:102436
Bone marrow mesenchymal stem cells and exercise restore motor function following spinal cord injury by activating PI3K/AKT/mTOR pathway.
Sun X, Huang LY, Pan HX, Li LJ, Wang L, Pei GQ, Wang Y, Zhang Q, Cheng HX, He CQ, Wei Q
Neural regeneration research 2023 May;18(5):1067-1075
Neural regeneration research 2023 May;18(5):1067-1075
Double-target neural circuit-magnetic stimulation improves motor function in spinal cord injury by attenuating astrocyte activation.
Zhao D, Zhang Y, Zheng Y, Li XT, Sun CC, Yang Q, Xie Q, Xu DS
Neural regeneration research 2023 May;18(5):1062-1066
Neural regeneration research 2023 May;18(5):1062-1066
The BET PROTAC inhibitor dBET6 protects against retinal degeneration and inhibits the cGAS-STING in response to light damage.
Zhu X, Liu W, Tang X, Chen Y, Ge X, Ke Q, Liang X, Gan Y, Zheng Y, Zou M, Deng M, Liu Y, Li DW, Gong L
Journal of neuroinflammation 2023 May 22;20(1):119
Journal of neuroinflammation 2023 May 22;20(1):119
Multi-omics analysis of a drug-induced model of bipolar disorder in zebrafish.
Li Y, Zhang L, Mao M, He L, Wang T, Pan Y, Zhao X, Li Z, Mu X, Qian Y, Qiu J
iScience 2023 May 19;26(5):106744
iScience 2023 May 19;26(5):106744
Mesenchymal stem cells transplantation combined with IronQ attenuates ICH-induced inflammation response via Mincle/syk signaling pathway.
Yang G, Kantapan J, Mazhar M, Bai X, Zou Y, Wang H, Huang B, Yang S, Dechsupa N, Wang L
Stem cell research & therapy 2023 May 15;14(1):131
Stem cell research & therapy 2023 May 15;14(1):131
Endothelial depletion of Atg7 triggers astrocyte-microvascular disassociation at blood-brain barrier.
Liu H, Wei JY, Li Y, Ban M, Sun Q, Wang HJ, Zhao D, Tong PG, Wang L, Wang KJ, Yue JL, Zhang HY, Fang WG, Liu DX, Shang DS, Li B, Jin YP, Cao L, Zhao WD, Chen YH
The Journal of cell biology 2023 May 1;222(5)
The Journal of cell biology 2023 May 1;222(5)
HSPA1A ameliorated spinal cord injury in rats by inhibiting apoptosis to exert neuroprotective effects.
He X, Guo X, Deng B, Kang J, Liu W, Zhang G, Wang Y, Yang Y, Kang X
Experimental neurology 2023 Mar;361:114301
Experimental neurology 2023 Mar;361:114301
LAMP-2A ablation in hippocampal CA1 astrocytes confers cerebroprotection and ameliorates neuronal injury after global brain ischemia.
Fu HY, Cui Y, Li Q, Wang D, Li H, Yang L, Wang DJ, Zhou JW
Brain pathology (Zurich, Switzerland) 2023 Mar;33(2):e13114
Brain pathology (Zurich, Switzerland) 2023 Mar;33(2):e13114
β2-Microglobulin exacerbates neuroinflammation, brain damage, and cognitive impairment after stroke in rats.
Chen F, Liu J, Li FQ, Wang SS, Zhang YY, Lu YY, Hu FF, Yao RQ
Neural regeneration research 2023 Mar;18(3):603-608
Neural regeneration research 2023 Mar;18(3):603-608
Deletion of Bak1 alleviates microglial necroptosis and neuroinflammation after experimental subarachnoid hemorrhage.
Qiu X, Tao Q, Zhang L, Kuang C, Xie Y, Zhang L, Yin S, Peng J, Jiang Y
Journal of neurochemistry 2023 Mar;164(6):829-846
Journal of neurochemistry 2023 Mar;164(6):829-846
Isolation, culture, and characterization of duck primary neurons.
Yang S, Wu J, Xian X, Chen Q
Poultry science 2023 Mar;102(3):102485
Poultry science 2023 Mar;102(3):102485
Kynurenic acid blunts A1 astrocyte activation against neurodegeneration in HIV-associated neurocognitive disorders.
Lun J, Li Y, Gao X, Gong Z, Chen X, Zou J, Zhou C, Huang Y, Zhou B, Huang P, Cao H
Journal of neuroinflammation 2023 Mar 30;20(1):87
Journal of neuroinflammation 2023 Mar 30;20(1):87
Azithromycin and Sildenafil May Have Protective Effects on Retinal Ganglion Cells via Different Pathways: Study in a Rodent Microbead Model.
Sela TC, Zahavi A, Friedman-Gohas M, Weiss S, Sternfeld A, Ilguisonis A, Badash D, Geffen N, Ofri R, BarKana Y, Goldenberg-Cohen N
Pharmaceuticals (Basel, Switzerland) 2023 Mar 24;16(4)
Pharmaceuticals (Basel, Switzerland) 2023 Mar 24;16(4)
Swimming training combined with fecal microbial transplantation protects motor functions in rats with spinal cord injury by improving the intestinal system.
Ouyang S, Wang X, Chen Y, Deng L, Yang X, Hu S, Wu S
Neuroscience letters 2023 Mar 16;799:137104
Neuroscience letters 2023 Mar 16;799:137104
Activation of TLR7-mediated autophagy increases epileptic susceptibility via reduced KIF5A-dependent GABA(A) receptor transport in a murine model.
Liu J, Ke P, Guo H, Gu J, Liu Y, Tian X, Wang X, Xiao F
Experimental & molecular medicine 2023 Jun;55(6):1159-1173
Experimental & molecular medicine 2023 Jun;55(6):1159-1173
Blocking Two-Pore Domain Potassium Channel TREK-1 Inhibits the Activation of A1-Like Reactive Astrocyte Through the NF-κB Signaling Pathway in a Rat Model of Major Depressive Disorder.
Cong T, Sun Y, Zhou Y, Wu H, Li L, Chu Z, Chen X, Li J, Zhao D, Wang Y, Liu Y, Yin S, Xiao Z
Neurochemical research 2023 Jun;48(6):1737-1754
Neurochemical research 2023 Jun;48(6):1737-1754
Glial cell line-derived neurotrophic factor and brain-derived neurotrophic factor regulate the interaction between astrocytes and Schwann cells at the trigeminal root entry zone.
Adam MI, Lin L, Makin AM, Zhang XF, Zhou LX, Liao XY, Zhao L, Wang F, Luo DS
Neural regeneration research 2023 Jun;18(6):1364-1370
Neural regeneration research 2023 Jun;18(6):1364-1370
HDAC6 Deficiency Has Moderate Effects on Behaviors and Parkinson's Disease Pathology in Mice.
Zhao J, He Y, Duan Y, Ma Y, Dong H, Zhang X, Fang R, Zhang Y, Yu M, Huang F
International journal of molecular sciences 2023 Jun 9;24(12)
International journal of molecular sciences 2023 Jun 9;24(12)
Tonic Meningeal Interleukin-10 Upregulates Delta Opioid Receptor to Prevent Relapse to Pain.
Inyang KE, Sim J, Clark KB, Matan G, Monahan K, Evans C, Beng P, Ma JV, Heijnen CJ, Dantzer R, Scherrer G, Kavelaars A, Bernard M, Aldhamen Y, Folger JK, Laumet G
bioRxiv : the preprint server for biology 2023 Jun 9;
bioRxiv : the preprint server for biology 2023 Jun 9;
Limb Remote Ischemic Postconditioning Improves Glymphatic Dysfunction After Cerebral Ischemia-Reperfusion Injury.
Li X, Tan X, Zhou Q, Xie Z, Meng W, Pang Y, Huang L, Ding Z, Hu Y, Li R, Huang G, Li H
Neuroscience 2023 Jun 15;521:20-30
Neuroscience 2023 Jun 15;521:20-30
Lymphocyte-Related Immunomodulatory Therapy with Siponimod (BAF-312) Improves Outcomes in Mice with Acute Intracerebral Hemorrhage.
Zhang Z, Li Y, Shi J, Zhu L, Dai Y, Fu P, Liu S, Hong M, Zhang J, Wang J, Jiang C
Aging and disease 2023 Jun 1;14(3):966-991
Aging and disease 2023 Jun 1;14(3):966-991
Parthenolide alleviates microglia-mediated neuroinflammation via MAPK/TRIM31/NLRP3 signaling to ameliorate cognitive disorder.
Fan M, Wang C, Zhao X, Jiang Y, Wang C
International immunopharmacology 2023 Jul;120:110287
International immunopharmacology 2023 Jul;120:110287
Ketogenic diet attenuates neuroinflammation and induces conversion of M1 microglia to M2 in an EAE model of multiple sclerosis by regulating the NF-κB/NLRP3 pathway and inhibiting HDAC3 and P2X7R activation.
Sun W, Wang Q, Zhang R, Zhang N
Food & function 2023 Jul 31;14(15):7247-7269
Food & function 2023 Jul 31;14(15):7247-7269
Ginsenoside-Rg1 synergized with voluntary running exercise protects against glial activation and dysregulation of neuronal plasticity in depression.
Wang W, Wang L, Wang L, Li Y, Lan T, Wang C, Chen X, Chen S, Yu S
Food & function 2023 Jul 31;14(15):7222-7239
Food & function 2023 Jul 31;14(15):7222-7239
Schwann cells regulate tumor cells and cancer-associated fibroblasts in the pancreatic ductal adenocarcinoma microenvironment.
Xue M, Zhu Y, Jiang Y, Han L, Shi M, Su R, Wang L, Xiong C, Wang C, Wang T, Deng S, Wu D, Cao Y, Dong L, Bai F, Zhao S, Deng X, Peng C, Li H, Chen J, Shen B, Jiang L, Chen H
Nature communications 2023 Jul 31;14(1):4600
Nature communications 2023 Jul 31;14(1):4600
Modulation of the Proliferative Pathway, Neuroinflammation and Pain in Endometriosis.
Interdonato L, Marino Y, D'Amico R, Cordaro M, Siracusa R, Impellizzeri D, Macrì F, Fusco R, Cuzzocrea S, Di Paola R
International journal of molecular sciences 2023 Jul 21;24(14)
International journal of molecular sciences 2023 Jul 21;24(14)
Multi-omics analysis reveals BDE47 induces depression-like behaviors in mice by interfering with the 2-arachidonoyl glycerol-associated microbiota-gut-brain axis.
Wang CQ, Su Z, Dai CG, Song JL, Qian B
Ecotoxicology and environmental safety 2023 Jul 1;259:115041
Ecotoxicology and environmental safety 2023 Jul 1;259:115041
Repeated sevoflurane exposures inhibit neurogenesis by inducing the upregulation of glutamate transporter 1 in astrocytes.
Kong F, Zhang Y, Wang T, Zhong L, Feng C, Wu Y
The European journal of neuroscience 2023 Jan;57(2):217-232
The European journal of neuroscience 2023 Jan;57(2):217-232
Clptm1, a new target in suppressing epileptic seizure by regulating GABA(A) R-mediated inhibitory synaptic transmission in a PTZ-induced epilepsy model.
Zhang XL, Zhou JY, Zhang P, Lin L, Mei R, Zhang FL, Chen YM, Li R
The Kaohsiung journal of medical sciences 2023 Jan;39(1):61-69
The Kaohsiung journal of medical sciences 2023 Jan;39(1):61-69
Fra-1 induces apoptosis and neuroinflammation by targeting S100A8 to modulate TLR4 pathways in spinal cord ischemia/reperfusion injury.
Chen Y, Dong Y, Zhang ZL, Han J, Chen FS, Tong XY, Ma H
Brain pathology (Zurich, Switzerland) 2023 Jan;33(1):e13113
Brain pathology (Zurich, Switzerland) 2023 Jan;33(1):e13113
Ginsenoside Rg1 promotes astrocyte-to-neuron transdifferentiation in rat and its possible mechanism.
Shen K, Wu D, Sun B, Zhu Y, Wang H, Zou W, Ma Y, Lu Z
CNS neuroscience & therapeutics 2023 Jan;29(1):256-269
CNS neuroscience & therapeutics 2023 Jan;29(1):256-269
Tocilizumab promotes repair of spinal cord injury by facilitating the restoration of tight junctions between vascular endothelial cells.
Luo Y, Yao F, Shi Y, Zhu Z, Xiao Z, You X, Liu Y, Yu S, Tian D, Cheng L, Zheng M, Jing J
Fluids and barriers of the CNS 2023 Jan 9;20(1):1
Fluids and barriers of the CNS 2023 Jan 9;20(1):1
Role of NF-κB in lead exposure-induced activation of astrocytes based on bioinformatics analysis of hippocampal proteomics.
Fan S, Weixuan W, Han H, Liansheng Z, Gang L, Jierui W, Yanshu Z
Chemico-biological interactions 2023 Jan 25;370:110310
Chemico-biological interactions 2023 Jan 25;370:110310
Integration of genetically engineered virus nanofibers and fibrin to form injectable fibrous neuron-rich hydrogels and enable neural differentiation.
Chen Y, Liu X, Yang M, Sun W, Mao C
Journal of materials chemistry. B 2023 Jan 25;11(4):802-815
Journal of materials chemistry. B 2023 Jan 25;11(4):802-815
Platelet-Rich Plasma Gel-Loaded Collagen/Chitosan Composite Film Accelerated Rat Sciatic Nerve Injury Repair.
Yuan B, Zheng X, Wu ML, Yang Y, Chen JW, Gao HC, Liu J
ACS omega 2023 Jan 24;8(3):2931-2941
ACS omega 2023 Jan 24;8(3):2931-2941
Superenhancer activation of KLHDC8A drives glioma ciliation and hedgehog signaling.
Lee D, Gimple RC, Wu X, Prager BC, Qiu Z, Wu Q, Daggubati V, Mariappan A, Gopalakrishnan J, Sarkisian MR, Raleigh DR, Rich JN
The Journal of clinical investigation 2023 Jan 17;133(2)
The Journal of clinical investigation 2023 Jan 17;133(2)
Thioflavin S Staining and Amyloid Formation Are Unique to Mixed Tauopathies.
Fiock KL, Betters RK, Hefti MM
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2023 Feb;71(2):73-86
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2023 Feb;71(2):73-86
The protective effect of inhibiting mitochondrial fission on the juvenile rat brain following PTZ kindling through inhibiting the BCL2L13/LC3 mitophagy pathway.
Fang Q, Zheng S, Chen Q, Chen L, Yang Y, Wang Y, Zhang H, Chen J
Metabolic brain disease 2023 Feb;38(2):453-466
Metabolic brain disease 2023 Feb;38(2):453-466
Human cytomegalovirus pUL97 upregulates SOCS3 expression via transcription factor RFX7 in neural progenitor cells.
Wang XZ, Wen L, Zhou YP, Huang SN, Yang B, Cheng S, Zeng WB, Mei MJ, Sun JY, Jiang X, Cheng H, Luo MH
PLoS pathogens 2023 Feb;19(2):e1011166
PLoS pathogens 2023 Feb;19(2):e1011166
Caffeic acid protects against atherosclerotic lesions and cognitive decline in ApoE(-/-) mice.
Sun R, Wu T, Xing S, Wei S, Bielicki JK, Pan X, Zhou M, Chen J
Journal of pharmacological sciences 2023 Feb;151(2):110-118
Journal of pharmacological sciences 2023 Feb;151(2):110-118
Honokiol alleviated neurodegeneration by reducing oxidative stress and improving mitochondrial function in mutant SOD1 cellular and mouse models of amyotrophic lateral sclerosis.
Zhou Y, Tang J, Lan J, Zhang Y, Wang H, Chen Q, Kang Y, Sun Y, Feng X, Wu L, Jin H, Chen S, Peng Y
Acta pharmaceutica Sinica. B 2023 Feb;13(2):577-597
Acta pharmaceutica Sinica. B 2023 Feb;13(2):577-597
A versatile vessel casting method for fine mapping of vascular networks using a hydrogel-based lipophilic dye solution.
Zhu J, Liu X, Xu J, Deng Y, Wang P, Liu Z, Yang Q, Li D, Yu T, Zhu D
Cell reports methods 2023 Feb 27;3(2):100407
Cell reports methods 2023 Feb 27;3(2):100407
Peroxiredoxin-6 Released by Astrocytes Contributes to Neuroapoptosis During Ischemia.
Hou JY, Zhou XL, Wang XY, Liang J, Xue Q
Neuroscience 2023 Feb 21;512:59-69
Neuroscience 2023 Feb 21;512:59-69
A Simple 3D Cell Culture Method for Studying the Interactions between Human Mesenchymal Stromal/Stem Cells and Patients Derived Glioblastoma.
Oliver L, Álvarez-Arenas A, Salaud C, Jiménez-Sanchez J, Calvo GF, Belmonte-Beitia J, Blandin S, Vidal L, Pérez V, Heymann D, Vallette FM
Cancers 2023 Feb 18;15(4)
Cancers 2023 Feb 18;15(4)
Circular RNA METTL9 contributes to neuroinflammation following traumatic brain injury by complexing with astrocytic SND1.
Huang C, Sun L, Xiao C, You W, Sun L, Wang S, Zhang Z, Liu S
Journal of neuroinflammation 2023 Feb 17;20(1):39
Journal of neuroinflammation 2023 Feb 17;20(1):39
Enrofloxacin exposure induces anxiety-like behavioral responses in zebrafish by affecting the microbiota-gut-brain axis.
Tian D, Shi W, Yu Y, Zhou W, Tang Y, Zhang W, Huang L, Han Y, Liu G
The Science of the total environment 2023 Feb 1;858(Pt 3):160094
The Science of the total environment 2023 Feb 1;858(Pt 3):160094
Bumetanide Rescues Aquaporin-4 Depolarization via Suppressing β-Dystroglycan Cleavage and Provides Neuroprotection in Rat Retinal Ischemia-Reperfusion Injury.
Chen C, Fan P, Zhang L, Xue K, Hu J, Huang J, Lu W, Xu J, Xu S, Qiu G, Ran J, Gan S
Neuroscience 2023 Feb 1;510:95-108
Neuroscience 2023 Feb 1;510:95-108
Neurotoxic A1 astrocytes promote neuronal ferroptosis via CXCL10/CXCR3 axis in epilepsy.
Liang P, Zhang X, Zhang Y, Wu Y, Song Y, Wang X, Chen T, Liu W, Peng B, Yin J, He F, Fan Y, Han S, He X
Free radical biology & medicine 2023 Feb 1;195:329-342
Free radical biology & medicine 2023 Feb 1;195:329-342
Mitochondrial fission drives neuronal metabolic burden to promote stress susceptibility in male mice.
Dong WT, Long LH, Deng Q, Liu D, Wang JL, Wang F, Chen JG
Nature metabolism 2023 Dec;5(12):2220-2236
Nature metabolism 2023 Dec;5(12):2220-2236
Astrocytes and microglia-targeted Danshensu liposomes enhance the therapeutic effects on cerebral ischemia-reperfusion injury.
Bai M, Cui N, Liao Y, Guo C, Li L, Yin Y, Wen A, Wang J, Ye W, Ding Y
Journal of controlled release : official journal of the Controlled Release Society 2023 Dec;364:473-489
Journal of controlled release : official journal of the Controlled Release Society 2023 Dec;364:473-489
Effects of electroacupuncture on glial scar generation in SCI model rats.
Hu Y, Zhao H, Shi S, Zhao Y, Gao X, Sun J, Li Z, Yao H
Anatomical record (Hoboken, N.J. : 2007) 2023 Dec;306(12):3156-3168
Anatomical record (Hoboken, N.J. : 2007) 2023 Dec;306(12):3156-3168
Epstein-Barr virus: To be a trigger of autoimmune glial fibrillary acidic protein astrocytopathy?
Li XL, Wang JY, Li LK, Yang CL, Zhao XL, Yang B, Zhang P, Liu B, Li YB, Zhang ZX, Duan RS
CNS neuroscience & therapeutics 2023 Dec;29(12):4139-4146
CNS neuroscience & therapeutics 2023 Dec;29(12):4139-4146
Ischemic Preconditioning Alleviates Cerebral Ischemia-Reperfusion Injury by Interfering With Glycocalyx.
Zhang YN, Wu Q, Zhang NN, Chen HS
Translational stroke research 2023 Dec;14(6):929-940
Translational stroke research 2023 Dec;14(6):929-940
P-hydroxy benzaldehyde facilitates reprogramming of reactive astrocytes into neurons via endogenous transcriptional regulation.
Li X, Fan R, Xiang J, Yuan Y, Mao X, Zhou N
The International journal of neuroscience 2023 Dec;133(10):1096-1108
The International journal of neuroscience 2023 Dec;133(10):1096-1108
Pregabalin inhibits purinergic P2Y(2) receptor and TRPV4 to suppress astrocyte activation and to relieve neuropathic pain.
Song S, Wang Q, Qu Y, Gao W, Li D, Xu X, Yue S
European journal of pharmacology 2023 Dec 5;960:176140
European journal of pharmacology 2023 Dec 5;960:176140
Early-Stage Application of Agomir-137 Promotes Locomotor Recovery in a Mouse Model of Motor Cortex Injury.
Liu XT, Teng ZQ
International journal of molecular sciences 2023 Dec 5;24(24)
International journal of molecular sciences 2023 Dec 5;24(24)
Neuroinflammation-induced parvalbumin interneuron and oscillation deficits might contribute to neurobehavioral abnormities in a two-hit model of depression.
Liu QR, Shi CN, Wang F, Tong JH
Heliyon 2023 Aug;9(8):e18468
Heliyon 2023 Aug;9(8):e18468
Sirt1 Overexpression Inhibits Fibrous Scar Formation and Improves Functional Recovery After Cerebral Ischemic Injury Through the Deacetylation of 14-3-3ζ.
Chen Y, Huang J, Liu J, Zhu H, Li X, Wen J, Tian M, Ren J, Zhou L, Yang Q
Molecular neurobiology 2023 Aug;60(8):4795-4810
Molecular neurobiology 2023 Aug;60(8):4795-4810
Lycium barbarum glycopeptide targets PER2 to inhibit lipogenesis in glioblastoma by downregulating SREBP1c.
Yao J, Hui JW, Chen YJ, Luo DY, Yan JS, Zhang YF, Lan YX, Yan XR, Wang ZH, Fan H, Xia HC
Cancer gene therapy 2023 Aug;30(8):1084-1093
Cancer gene therapy 2023 Aug;30(8):1084-1093
Synergistic effects of lipopolysaccharide and rotenone on dopamine neuronal damage in rats.
He JY, Li DD, Wen Q, Qin TY, Long H, Zhang SB, Zhang F
CNS neuroscience & therapeutics 2023 Aug;29(8):2281-2291
CNS neuroscience & therapeutics 2023 Aug;29(8):2281-2291
Berberine-loaded MSC-derived sEVs encapsulated in injectable GelMA hydrogel for spinal cord injury repair.
Wang H, Tang Q, Lu Y, Chen C, Zhao YL, Xu T, Yang CW, Chen XQ
International journal of pharmaceutics 2023 Aug 25;643:123283
International journal of pharmaceutics 2023 Aug 25;643:123283
Bioactive NIR-II gold clusters for three-dimensional imaging and acute inflammation inhibition.
Ma H, Zhang X, Liu L, Huang Y, Sun S, Chen K, Xin Q, Liu P, Yan Y, Wang Y, Li Y, Liu H, Zhao R, Tan K, Chen X, Yuan X, Li Y, Liu Y, Dai H, Liu C, Wang H, Zhang XD
Science advances 2023 Aug 2;9(31):eadh7828
Science advances 2023 Aug 2;9(31):eadh7828
Exosomes secreted by mesenchymal stem cells delay brain aging by upregulating SIRT1 expression.
Zhang X, Liu T, Hou X, Zhou Z, Zhang F, Ma H, Wu X, Jiang J
Scientific reports 2023 Aug 14;13(1):13213
Scientific reports 2023 Aug 14;13(1):13213
Evaluation of BDE-47-induced neurodevelopmental toxicity in zebrafish embryos.
Zhuang J, Pan ZJ, Qin Y, Liang H, Zhang WF, Sun ZY, Shi HB
Environmental science and pollution research international 2023 Apr;30(18):54022-54034
Environmental science and pollution research international 2023 Apr;30(18):54022-54034
Microenvironmental modulation in tandem with human stem cell transplantation enhances functional recovery after chronic complete spinal cord injury.
Hashimoto S, Nagoshi N, Shinozaki M, Nakanishi K, Suematsu Y, Shibata T, Kawai M, Kitagawa T, Ago K, Kamata Y, Yasutake K, Koya I, Ando Y, Minoda A, Shindo T, Shibata S, Matsumoto M, Nakamura M, Okano H
Biomaterials 2023 Apr;295:122002
Biomaterials 2023 Apr;295:122002
Lipid-accumulated reactive astrocytes promote disease progression in epilepsy.
Chen ZP, Wang S, Zhao X, Fang W, Wang Z, Ye H, Wang MJ, Ke L, Huang T, Lv P, Jiang X, Zhang Q, Li L, Xie ST, Zhu JN, Hang C, Chen D, Liu X, Yan C
Nature neuroscience 2023 Apr;26(4):542-554
Nature neuroscience 2023 Apr;26(4):542-554
Geranylgeranylacetone-induced heat shock protein70 expression reduces retinal ischemia-reperfusion injury through PI3K/AKT/mTOR signaling.
Zhang L, Xue K, Fan P, Chen C, Hu J, Huang J, Lu W, Xu J, Xu S, Ran J, Zhu S, Gan S
Experimental eye research 2023 Apr;229:109416
Experimental eye research 2023 Apr;229:109416
Engineered Extracellular Vesicle-Delivered CRISPR/CasRx as a Novel RNA Editing Tool.
Li T, Zhang L, Lu T, Zhu T, Feng C, Gao N, Liu F, Yu J, Chen K, Zhong J, Tang Q, Zhang Q, Deng X, Ren J, Zeng J, Zhou H, Zhu J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Apr;10(10):e2206517
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Apr;10(10):e2206517
Oral feeding of nanoplastics affects brain function of mice by inducing macrophage IL-1 signal in the intestine.
Yang Q, Dai H, Cheng Y, Wang B, Xu J, Zhang Y, Chen Y, Xu F, Ma Q, Lin F, Wang C
Cell reports 2023 Apr 25;42(4):112346
Cell reports 2023 Apr 25;42(4):112346
NOD-like receptor NLRC5 promotes neuroinflammation and inhibits neuronal survival in Parkinson's disease models.
Liu Z, Shen C, Li H, Tong J, Wu Y, Ma Y, Wang J, Wang Z, Li Q, Zhang X, Dong H, Yang Y, Yu M, Wang J, Zhou R, Fei J, Huang F
Journal of neuroinflammation 2023 Apr 18;20(1):96
Journal of neuroinflammation 2023 Apr 18;20(1):96
Mitochondrial-targeting fluorescent small molecule IR-780 alleviates radiation-induced brain injury.
Zhang C, Zheng J, Chen W, Yang W, Tan X, Fan X, Shen G, Qu L, Chen Z, Shi C
Brain research 2023 Apr 15;1805:148285
Brain research 2023 Apr 15;1805:148285
Cryo-Shocked Platelet Coupled with ROS-Responsive Nanomedicine for Targeted Treatment of Thromboembolic Disease.
Quan X, Liang X, Ding Y, Han Y, Li J, Yuan M, Li Y, Yuan Z, Wang R, Zhao Y
ACS nano 2023 Apr 11;17(7):6519-6533
ACS nano 2023 Apr 11;17(7):6519-6533
The role of reactive astrocytes in neurotoxicity induced by ultrafine particulate matter.
Li B, Chang X, Liang X, Liu T, Shen Y, Zhang Q, Yang X, Lyu Y, Liu L, Guo J, Wu M, Gao Y, Yan X, Wang T, Zhang W, Qiu Y, Zheng J
The Science of the total environment 2023 Apr 1;867:161416
The Science of the total environment 2023 Apr 1;867:161416
Functional OCT angiography reveals early retinal neurovascular dysfunction in diabetes with capillary resolution.
Liu K, Zhu T, Gao M, Yin X, Zheng R, Yan Y, Gao L, Ding Z, Ye J, Li P
Biomedical optics express 2023 Apr 1;14(4):1670-1684
Biomedical optics express 2023 Apr 1;14(4):1670-1684
Icariside II Attenuates Methamphetamine-Induced Neurotoxicity and Behavioral Impairments via Activating the Keap1-Nrf2 Pathway.
Huang J, Ding J, Wang Z, Li Y, He Y, Wang X, Fan H, Xie Q, Qiu P
Oxidative medicine and cellular longevity 2022;2022:8400876
Oxidative medicine and cellular longevity 2022;2022:8400876
The Dectin-1 Receptor Signaling Pathway Mediates the Remyelination Effect of Lentinan through Suppression of Neuroinflammation and Conversion of Microglia.
Zhang D, Jia Y, Sun X, Li H, Yin M, Li H, Dai L, Han L, Wang L, Qian M, Du J, Zhu K, Bao H
Journal of immunology research 2022;2022:3002304
Journal of immunology research 2022;2022:3002304
Diet-Induced High Serum Levels of Trimethylamine-N-oxide Enhance the Cellular Inflammatory Response without Exacerbating Acute Intracerebral Hemorrhage Injury in Mice.
Li C, Zhu L, Dai Y, Zhang Z, Huang L, Wang TJ, Fu P, Li Y, Wang J, Jiang C
Oxidative medicine and cellular longevity 2022;2022:1599747
Oxidative medicine and cellular longevity 2022;2022:1599747
Decitabine attenuates ischemic stroke by reducing astrocytes proliferation in rats.
Zhang Q, Li D, Zhao H, Zhang X
PloS one 2022;17(8):e0272482
PloS one 2022;17(8):e0272482
Conditional deletion of MAD2B in forebrain neurons enhances hippocampus-dependent learning and memory in mice.
Cheng L, Su Y, Zhi K, Xie Y, Zhang C, Meng X
Frontiers in cellular neuroscience 2022;16:956029
Frontiers in cellular neuroscience 2022;16:956029
Periodontitis Salivary Microbiota Aggravates Ischemic Stroke Through IL-17A.
Chen YL, Bai L, Dilimulati D, Shao S, Qiu C, Liu T, Xu S, Bai XB, Du LJ, Zhou LJ, Lin WZ, Meng XQ, Jin YC, Liu Y, Zhang XH, Duan SZ, Jia F
Frontiers in neuroscience 2022;16:876582
Frontiers in neuroscience 2022;16:876582
Rare KCND3 Loss-of-Function Mutation Associated With the SCA19/22.
Li M, Liu F, Hao X, Fan Y, Li J, Hu Z, Shi J, Fan L, Zhang S, Ma D, Guo M, Xu Y, Shi C
Frontiers in molecular neuroscience 2022;15:919199
Frontiers in molecular neuroscience 2022;15:919199
NF-κB and AP-1 are required for the lipopolysaccharide-induced expression of MCP-1, CXCL1, and Cx43 in cultured rat dorsal spinal cord astrocytes.
Lu Y, Li B, Xu A, Liang X, Xu T, Jin H, Xie Y, Wang R, Liu X, Gao X, Han Y, Zeng J
Frontiers in molecular neuroscience 2022;15:859558
Frontiers in molecular neuroscience 2022;15:859558
Blood-nerve barrier disruption and coagulation system activation induced by mechanical compression injury participate in the peripheral sensitization of trigeminal neuralgia.
Zhou LX, Lin SW, Qiu RH, Lin L, Guo YF, Luo DS, Li YQ, Wang F
Frontiers in molecular neuroscience 2022;15:1059980
Frontiers in molecular neuroscience 2022;15:1059980
Molar loss further exacerbates 2-VO-induced cognitive impairment associated with the activation of p38MAPK/NFκB pathway.
Lu Y, Pang Q, Wu Q, Luo B, Tang X, Jiang Q
Frontiers in aging neuroscience 2022;14:930016
Frontiers in aging neuroscience 2022;14:930016
Effect of β-hydroxybutyrate on behavioral alterations, molecular and morphological changes in CNS of multiple sclerosis mouse model.
Sun W, Wen M, Liu M, Wang Q, Liu Q, Li L, Siebert HC, Loers G, Zhang R, Zhang N
Frontiers in aging neuroscience 2022;14:1075161
Frontiers in aging neuroscience 2022;14:1075161
TAZ Induces Migration of Microglia and Promotes Neurological Recovery After Spinal Cord Injury.
Hu X, Huang J, Li Y, Dong L, Chen Y, Ouyang F, Li J, Li Z, Jing J, Cheng L
Frontiers in pharmacology 2022;13:938416
Frontiers in pharmacology 2022;13:938416
Coeloglossum viride Var. Bracteatum Extract Attenuates MPTP-Induced Neurotoxicity in vivo by Restoring BDNF-TrkB and FGF2-Akt Signaling Axis and Inhibiting RIP1-Driven Inflammation.
Lang XY, Hu Y, Bai JP, Wang J, Qin XY, Lan R
Frontiers in pharmacology 2022;13:903235
Frontiers in pharmacology 2022;13:903235
DAPT Attenuates Cadmium-Induced Toxicity in Mice by Inhibiting Inflammation and the Notch/HES-1 Signaling Axis.
Yang JY, Shen DY, Wang J, Dai JF, Qin XY, Hu Y, Lan R
Frontiers in pharmacology 2022;13:902796
Frontiers in pharmacology 2022;13:902796
Edaravone Dexborneol Treatment Attenuates Neuronal Apoptosis and Improves Neurological Function by Suppressing 4-HNE-Associated Oxidative Stress After Subarachnoid Hemorrhage.
Chen Q, Cai Y, Zhu X, Wang J, Gao F, Yang M, Mao L, Zhang Z, Sun B
Frontiers in pharmacology 2022;13:848529
Frontiers in pharmacology 2022;13:848529
Alpha-Asaronol Alleviates Dysmyelination by Enhancing Glutamate Transport Through the Activation of PPARγ-GLT-1 Signaling in Hypoxia-Ischemia Neonatal Rats.
Ge Y, Zhen F, Liu Z, Feng Z, Wang G, Zhang C, Wang X, Sun Y, Zheng X, Bai Y, Yao R
Frontiers in pharmacology 2022;13:766744
Frontiers in pharmacology 2022;13:766744
Dual Effects: Intrastriatal Injection of α-syn N103/tau N368 Preformed Fibrils Promotes Endogenous α-synuclein Aggregates in the Proximal Colon.
Wang J, Yang X, Zeng W, Zhang X, Yang X, Xu Y, Liu K, Zhang Z, Xu Y, Cao X
Journal of Parkinson's disease 2022;12(7):2097-2116
Journal of Parkinson's disease 2022;12(7):2097-2116
Continuous theta-burst stimulation enhances and sustains neurogenesis following ischemic stroke.
Zong X, Gu J, Zhou S, Ding D, Hu Y, Tucker L, Huang Z, Geng D, Gao D
Theranostics 2022;12(13):5710-5726
Theranostics 2022;12(13):5710-5726
Vagus nerve stimulation promotes the M1-to-M2 transition via inhibition of TLR4/NF-κB in microglial to rescue the reperfusion injury.
Zhang L, Zhang X, Liu Y, Wang S, Jia G
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2022 Sep;31(9):106596
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2022 Sep;31(9):106596
Temporal and Sex-Linked Protein Expression Dynamics in a Familial Model of Alzheimer's Disease.
Blasco Tavares Pereira Lopes F, Schlatzer D, Wang R, Li X, Feng E, Koyutürk M, Qi X, Chance MR
Molecular & cellular proteomics : MCP 2022 Sep;21(9):100280
Molecular & cellular proteomics : MCP 2022 Sep;21(9):100280
Bilateral intracerebroventricular injection of streptozotocin induces AD-like behavioral impairments and neuropathological features in mice: Involved with the fundamental role of neuroinflammation.
Fan M, Liu S, Sun HM, Ma MD, Gao YJ, Qi CC, Xia QR, Ge JF
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Sep;153:113375
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Sep;153:113375
Human PMSCs-derived small extracellular vesicles alleviate neuropathic pain through miR-26a-5p/Wnt5a in SNI mice model.
Lu Y, Zhang J, Zeng F, Wang P, Guo X, Wang H, Qin Z, Tao T
Journal of neuroinflammation 2022 Sep 7;19(1):221
Journal of neuroinflammation 2022 Sep 7;19(1):221
Delivery of miRNAs through Metal-Organic Framework Nanoparticles for Assisting Neural Stem Cell Therapy for Ischemic Stroke.
Yang H, Han M, Li J, Ke H, Kong Y, Wang W, Wang L, Ma W, Qiu J, Wang X, Xin T, Liu H
ACS nano 2022 Sep 27;16(9):14503-14516
ACS nano 2022 Sep 27;16(9):14503-14516
Imatinib inhibits pericyte-fibroblast transition and inflammation and promotes axon regeneration by blocking the PDGF-BB/PDGFRβ pathway in spinal cord injury.
Yao F, Luo Y, Liu YC, Chen YH, Li YT, Hu XY, You XY, Yu SS, Li ZY, Chen L, Tian DS, Zheng MG, Cheng L, Jing JH
Inflammation and regeneration 2022 Sep 26;42(1):44
Inflammation and regeneration 2022 Sep 26;42(1):44
Apelin-13 reduces lipopolysaccharide-induced neuroinflammation and cognitive impairment via promoting glucocorticoid receptor expression and nuclear translocation.
Hu S, Shen P, Chen B, Tian SW, You Y
Neuroscience letters 2022 Sep 25;788:136850
Neuroscience letters 2022 Sep 25;788:136850
A Mouse Model of Neurodegeneration Induced by Blade Penetrating Stab Wound to the Hippocampus.
He BD, Liu CM, Teng ZQ
Biology 2022 Sep 18;11(9)
Biology 2022 Sep 18;11(9)
Pedigree-based study to identify GOLGB1 as a risk gene for bipolar disorder.
Liu FR, Zhou Y, Wang Y, Huang LL, Zhang X, Luo H, Wu SY, Lyu HY, Huang LH, Xu H, Zhang YW
Translational psychiatry 2022 Sep 17;12(1):390
Translational psychiatry 2022 Sep 17;12(1):390
Flufenamic acid improves survival and neurologic outcome after successful cardiopulmonary resuscitation in mice.
Chen J, Chang Y, Zhu J, Peng Y, Li Z, Zhang K, Zhang Y, Lin C, Lin Z, Pan S, Huang K
Journal of neuroinflammation 2022 Sep 1;19(1):214
Journal of neuroinflammation 2022 Sep 1;19(1):214
Rac-deficient cerebellar granule neurons die before they migrate to the internal granule layer.
Katayama KI, Zheng Y, Inoue N
Scientific reports 2022 Sep 1;12(1):14848
Scientific reports 2022 Sep 1;12(1):14848
Effects of intraperitoneal injection of lipopolysaccharide-induced peripheral inflammation on dopamine neuron damage in rat midbrain.
Yang QY, Li XW, Yang R, Qin TY, Long H, Zhang SB, Zhang F
CNS neuroscience & therapeutics 2022 Oct;28(10):1624-1636
CNS neuroscience & therapeutics 2022 Oct;28(10):1624-1636
Celastrol inhibits pathologic neovascularization in oxygen-induced retinopathy by targeting the miR-17-5p/HIF-1α/VEGF pathway.
Zhao K, Jiang Y, Zhang J, Shi J, Zheng P, Yang C, Chen Y
Cell cycle (Georgetown, Tex.) 2022 Oct;21(19):2091-2108
Cell cycle (Georgetown, Tex.) 2022 Oct;21(19):2091-2108
Apelin-13 attenuates depressive-like behaviors induced by chronic unpredictable mild stress via activating AMPK/PGC-1α/FNDC5/BDNF pathway.
Hu S, He L, Chen B, You Y
Peptides 2022 Oct;156:170847
Peptides 2022 Oct;156:170847
Neuroprotective Effect of Azithromycin Following Induction of Optic Nerve Crush in Wild Type and Immunodeficient Mice.
Zloto O, Zahavi A, Richard S, Friedman-Gohas M, Weiss S, Goldenberg-Cohen N
International journal of molecular sciences 2022 Oct 6;23(19)
International journal of molecular sciences 2022 Oct 6;23(19)
Treadmill Exercise Modulates Intestinal Microbes and Suppresses LPS Displacement to Alleviate Neuroinflammation in the Brains of APP/PS1 Mice.
Yuan S, Yang J, Jian Y, Lei Y, Yao S, Hu Z, Liu X, Tang C, Liu W
Nutrients 2022 Oct 5;14(19)
Nutrients 2022 Oct 5;14(19)
LY6E protein facilitates adeno-associated virus crossing in a biomimetic chip model of the human blood-brain barrier.
Liu D, Zhu M, Lin Y, Li M, Huang R, Yang L, Song Y, Diao Y, Yang C
Lab on a chip 2022 Oct 25;22(21):4180-4190
Lab on a chip 2022 Oct 25;22(21):4180-4190
Oncofetal protein IGF2BP1 regulates IQGAP3 expression to maintain stem cell potential in cancer.
Myint K, Chuang LSH, Teh YX, Mawan NA, Shi EJ, Mok MMH, Nuttonmanit N, Matsuo J, Li Y, Yang H, Okabe A, Kaneda A, Osato M, So JB, Yong WP, Tan P, Yeoh KG, Ito Y
iScience 2022 Oct 21;25(10):105194
iScience 2022 Oct 21;25(10):105194
S100A8 regulates autophagy-dependent ferroptosis in microglia after experimental subarachnoid hemorrhage.
Tao Q, Qiu X, Li C, Zhou J, Gu L, Zhang L, Pang J, Zhang L, Yin S, Jiang Y, Peng J
Experimental neurology 2022 Nov;357:114171
Experimental neurology 2022 Nov;357:114171
Differential roles of NMDAR subunits 2A and 2B in mediating peripheral and central sensitization contributing to orofacial neuropathic pain.
Zhang YY, Liu F, Fang ZH, Li YL, Liao HL, Song QX, Zhou C, Shen JF
Brain, behavior, and immunity 2022 Nov;106:129-146
Brain, behavior, and immunity 2022 Nov;106:129-146
Functions of retinal astrocytes and Müller cells in mammalian myopia.
Zhang X, Yu X, Wen Y, Jin L, Zhang L, Zhu H, Zhang D, Xie C, Guo D, Tong J, Shen Y
BMC ophthalmology 2022 Nov 24;22(1):451
BMC ophthalmology 2022 Nov 24;22(1):451
Spinal cord astrocytes regulate myocardial ischemia-reperfusion injury.
Wu C, Liu R, Luo Z, Sun M, Qile M, Xu S, Jin S, Zhang L, Gross ER, Zhang Y, He S
Basic research in cardiology 2022 Nov 11;117(1):56
Basic research in cardiology 2022 Nov 11;117(1):56
Decreased Spire2 Expression is Involved in Epilepsy.
Hao L, Zhang H, Peng X, Yang Y, Yang M, Guo Y, Wang X, Jing W
Neuroscience 2022 Nov 10;504:1-9
Neuroscience 2022 Nov 10;504:1-9
Administration of C5a Receptor Antagonist Improves the Efficacy of Human Induced Pluripotent Stem Cell-Derived Neural Stem/Progenitor Cell Transplantation in the Acute Phase of Spinal Cord Injury.
Shibata R, Nagoshi N, Kajikawa K, Ito S, Shibata S, Shindo T, Khazaei M, Nori S, Kohyama J, Fehlings MG, Matsumoto M, Nakamura M, Okano H
Journal of neurotrauma 2022 May;39(9-10):667-682
Journal of neurotrauma 2022 May;39(9-10):667-682
sEVs(RVG) selectively delivers antiviral siRNA to fetus brain, inhibits ZIKV infection and mitigates ZIKV-induced microcephaly in mouse model.
Zhang R, Fu Y, Cheng M, Ma W, Zheng N, Wang Y, Wu Z
Molecular therapy : the journal of the American Society of Gene Therapy 2022 May 4;30(5):2078-2091
Molecular therapy : the journal of the American Society of Gene Therapy 2022 May 4;30(5):2078-2091
Adeno-associated virus-mediated in vivo suppression of expression of EPHX2 gene modulates the activity of paraventricular nucleus neurons in spontaneously hypertensive rats.
Zhu X, Li K, Gao Y
Biochemical and biophysical research communications 2022 May 28;606:121-127
Biochemical and biophysical research communications 2022 May 28;606:121-127
Inhibition of ROCK2 kinase activity improved behavioral deficits and reduced neuron damage in a DEACMP rat model.
Xu L, Liu X, Guo C, Wang C, Zhao J, Zhang X, Li W, Zhang P, Gu R
Brain research bulletin 2022 Mar;180:24-30
Brain research bulletin 2022 Mar;180:24-30
Involvement of the BDNF-TrkB-KCC2 pathway in neuropathic pain after brachial plexus avulsion.
Zhao S, Wang F, Wang L, Xu Y, Lv L, Duan W, Bai R, Meng Z, Shao X
Brain and behavior 2022 Mar;12(3):e2464
Brain and behavior 2022 Mar;12(3):e2464
Gut microbiota shapes social dominance through modulating HDAC2 in the medial prefrontal cortex.
Wang T, Xu J, Xu Y, Xiao J, Bi N, Gu X, Wang HL
Cell reports 2022 Mar 8;38(10):110478
Cell reports 2022 Mar 8;38(10):110478
Salidroside alleviates cadmium-induced toxicity in mice by restoring the notch/HES-1 and RIP1-driven inflammatory signaling axis.
Shu XM, Hu Y, Fang X, Wang J, Qin XY, Lan R
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2022 Jun;71(5-6):615-626
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2022 Jun;71(5-6):615-626
Mechanistic Insights into Ameliorating Effect of Geraniol on D-Galactose Induced Memory Impairment in Rats.
Atef MM, Emam MN, Abo El Gheit RE, Elbeltagi EM, Alshenawy HA, Radwan DA, Younis RL, Abd-Ellatif RN
Neurochemical research 2022 Jun;47(6):1664-1678
Neurochemical research 2022 Jun;47(6):1664-1678
Effects of ketogenic diet on cognitive functions of mice fed high-fat-high-cholesterol diet.
Lin DT, Kao NJ, Cross TL, Lee WJ, Lin SH
The Journal of nutritional biochemistry 2022 Jun;104:108974
The Journal of nutritional biochemistry 2022 Jun;104:108974
Pancreatic Stellate Cells Prolong Ex Vivo Islet Viability and Function and Improve Engraftment.
Paul PK, Das R, Drow TJ, de Souza AH, Balamurugan AN, Belt Davis D, Galipeau J
Stem cells translational medicine 2022 Jun 22;11(6):630-643
Stem cells translational medicine 2022 Jun 22;11(6):630-643
Attenuation of histone H4 lysine 16 acetylation (H4K16ac) elicits a neuroprotection against ischemic stroke by alleviating the autophagic/lysosomal dysfunction in neurons at the penumbra.
Lingling D, Miaomiao Q, Yili L, Hongyun H, Yihao D
Brain research bulletin 2022 Jun 15;184:24-33
Brain research bulletin 2022 Jun 15;184:24-33
Anti-IgLON5 antibodies cause progressive behavioral and neuropathological changes in mice.
Ni Y, Feng Y, Shen D, Chen M, Zhu X, Zhou Q, Gao Y, Liu J, Zhang Q, Shen Y, Peng L, Zeng Z, Yin D, Hu J, Chen S
Journal of neuroinflammation 2022 Jun 11;19(1):140
Journal of neuroinflammation 2022 Jun 11;19(1):140
Astragalin attenuates AlCl(3)/D-galactose-induced aging-like disorders by inhibiting oxidative stress and neuroinflammation.
Hu Y, Fang X, Wang J, Ren TT, Zhao YY, Dai JF, Qin XY, Lan R
Neurotoxicology 2022 Jul;91:60-68
Neurotoxicology 2022 Jul;91:60-68
MG53 protein rejuvenates hUC-MSCs and facilitates their therapeutic effects in AD mice by activating Nrf2 signaling pathway.
Ma S, Zhou X, Wang Y, Li Z, Wang Y, Shi J, Guan F
Redox biology 2022 Jul;53:102325
Redox biology 2022 Jul;53:102325
N-Acetylcysteine alleviates spinal cord injury in rats after early decompression surgery by regulating inflammation and apoptosis.
Guo X, He J, Zhang R, Wang T, Chen J, Wang J, Wang Z, Chang G, Niu Y, Niu Z, Song J
Neurological research 2022 Jul;44(7):605-613
Neurological research 2022 Jul;44(7):605-613
Neuroprotective effects of CysLTR antagonist on Streptococcus pneumoniae-induced meningitis in rats.
Yu S, Chen X, Li X, Yan J, Jiang Y
Experimental and therapeutic medicine 2022 Jul;24(1):443
Experimental and therapeutic medicine 2022 Jul;24(1):443
Pulsed-Focused Ultrasound Provides Long-Term Suppression of Epileptiform Bursts in the Kainic Acid-Induced Epilepsy Rat Model.
Chu PC, Yu HY, Lee CC, Fisher R, Liu HL
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2022 Jul;19(4):1368-1380
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2022 Jul;19(4):1368-1380
UPF1/circRPPH1/ATF3 feedback loop promotes the malignant phenotype and stemness of GSCs.
Xu J, Zhang G, Hu J, Li H, Zhao J, Zong S, Guo Z, Jiang Y, Jing Z
Cell death & disease 2022 Jul 23;13(7):645
Cell death & disease 2022 Jul 23;13(7):645
Ror2 mediates chronic post-thoracotomy pain by inducing the transformation of A1/A2 reactive astrocytes in rats.
Liu C, Shen L, Xu L, Zhu A, Huang Y
Cellular signalling 2022 Jan;89:110183
Cellular signalling 2022 Jan;89:110183
The role of regulatory T cells on the activation of astrocytes in the brain of high-fat diet mice following lead exposure.
Wu L, Li S, Li C, He B, Lv L, Wang J, Wang J, Wang W, Zhang Y
Chemico-biological interactions 2022 Jan 5;351:109740
Chemico-biological interactions 2022 Jan 5;351:109740
Malignant Melanoma-Derived Exosomes Induce Endothelial Damage and Glial Activation on a Human BBB Chip Model.
Wang P, Wu Y, Chen W, Zhang M, Qin J
Biosensors 2022 Jan 31;12(2)
Biosensors 2022 Jan 31;12(2)
The adaptor SH2B1 and the phosphatase PTP4A1 regulate the phosphorylation of cytohesin-2 in myelinating Schwann cells in mice.
Miyamoto Y, Torii T, Homma K, Oizumi H, Ohbuchi K, Mizoguchi K, Takashima S, Yamauchi J
Science signaling 2022 Jan 25;15(718):eabi5276
Science signaling 2022 Jan 25;15(718):eabi5276
A congenital CMV infection model for follow-up studies of neurodevelopmental disorders, neuroimaging abnormalities, and treatment.
Zhou YP, Mei MJ, Wang XZ, Huang SN, Chen L, Zhang M, Li XY, Qin HB, Dong X, Cheng S, Wen L, Yang B, An XF, He AD, Zhang B, Zeng WB, Li XJ, Lu Y, Li HC, Li H, Zou WG, Redwood AJ, Rayner S, Cheng H, McVoy MA, Tang Q, Britt WJ, Zhou X, Jiang X, Luo MH
JCI insight 2022 Jan 11;7(1)
JCI insight 2022 Jan 11;7(1)
Folic Acid Inhibits Aging-Induced Telomere Attrition and Apoptosis in Astrocytes In Vivo and In Vitro.
Li Z, Zhou D, Zhang D, Zhao J, Li W, Sun Y, Chen Y, Liu H, Wilson JX, Qian Z, Huang G
Cerebral cortex (New York, N.Y. : 1991) 2022 Jan 10;32(2):286-297
Cerebral cortex (New York, N.Y. : 1991) 2022 Jan 10;32(2):286-297
Coeloglossum viride var. bracteatum extract attenuates Aβ-induced toxicity by inhibiting RIP1-driven inflammation and necroptosis.
Li XX, Lang XY, Ren TT, Wang J, Lan R, Qin XY
Journal of ethnopharmacology 2022 Jan 10;282:114606
Journal of ethnopharmacology 2022 Jan 10;282:114606
Neuroprotective effects of liraglutide against inflammation through the AMPK/NF-κB pathway in a mouse model of Parkinson's disease.
Cao B, Zhang Y, Chen J, Wu P, Dong Y, Wang Y
Metabolic brain disease 2022 Feb;37(2):451-462
Metabolic brain disease 2022 Feb;37(2):451-462
The histone deacetylase inhibitor belinostat ameliorates experimental autoimmune encephalomyelitis in mice by inhibiting TLR2/MyD88 and HDAC3/ NF-κB p65-mediated neuroinflammation.
Shen Y, Yang R, Zhao J, Chen M, Chen S, Ji B, Chen H, Liu D, Li L, Du G
Pharmacological research 2022 Feb;176:105969
Pharmacological research 2022 Feb;176:105969
The N-Terminal Region of Middle East Respiratory Syndrome Coronavirus Accessory Protein 8b Is Essential for Enhanced Virulence of an Attenuated Murine Coronavirus.
Li Y, Jin Y, Kuang L, Luo Z, Li F, Sun J, Zhu A, Zhuang Z, Wang Y, Wen L, Liu D, Chen C, Gan M, Zhao J, Zhao J
Journal of virology 2022 Feb 9;96(3):e0184221
Journal of virology 2022 Feb 9;96(3):e0184221
Neuroprotective effects of alisol A 24-acetate on cerebral ischaemia-reperfusion injury are mediated by regulating the PI3K/AKT pathway.
Lu T, Li H, Zhou Y, Wei W, Ding L, Zhan Z, Liu W, Tao J, Xue X
Journal of neuroinflammation 2022 Feb 7;19(1):37
Journal of neuroinflammation 2022 Feb 7;19(1):37
Exosomes derived from bone-marrow mesenchymal stem cells alleviate cognitive decline in AD-like mice by improving BDNF-related neuropathology.
Liu S, Fan M, Xu JX, Yang LJ, Qi CC, Xia QR, Ge JF
Journal of neuroinflammation 2022 Feb 7;19(1):35
Journal of neuroinflammation 2022 Feb 7;19(1):35
Silk fibroin nanofibrous scaffolds incorporated with microRNA-222 loaded chitosan nanoparticles for enhanced neuronal differentiation of neural stem cells.
Li Z, Meng Z, Zhao Z
Carbohydrate polymers 2022 Feb 1;277:118791
Carbohydrate polymers 2022 Feb 1;277:118791
Maternal sevoflurane exposure affects neural stem cell differentiation in offspring rats through NRF2 signaling.
Zhang Y, Kuai S, Zhang Y, Xue H, Wu Z, Zhao P
Neurotoxicology 2022 Dec;93:348-354
Neurotoxicology 2022 Dec;93:348-354
Histological and molecular characterization of glaucoma model induced by one or two injections of microbeads to the anterior chamber of mice.
Zahavi A, Friedman Gohas M, Sternfeld A, Daoud Zreiq N, Muhsinoglu O, Ofri R, BarKana Y, Goldenberg-Cohen N
International ophthalmology 2022 Dec;42(12):3763-3775
International ophthalmology 2022 Dec;42(12):3763-3775
Early Diagnosis of Murine Sepsis-Associated Encephalopathy Using Dynamic PET/CT Imaging and Multiparametric MRI.
Zhu T, Jiang J, Xiao Y, Xu D, Liang Z, Bi L, Yang M, Liang M, Li D, Lin Y
Molecular imaging and biology 2022 Dec;24(6):928-939
Molecular imaging and biology 2022 Dec;24(6):928-939
Astrocyte-derived sEVs alleviate fibrosis and promote functional recovery after spinal cord injury in rats.
Lu Y, Chen C, Wang H, Du R, Ji J, Xu T, Yang C, Chen X
International immunopharmacology 2022 Dec;113(Pt A):109322
International immunopharmacology 2022 Dec;113(Pt A):109322
Dysregulation of ErbB4 Signaling Pathway in the Dorsal Hippocampus after Neonatal Hypoxia-Ischemia and Late Deficits in PV(+) Interneurons, Synaptic Plasticity and Working Memory.
Spahic H, Parmar P, Miller S, Emerson PC, Lechner C, St Pierre M, Rastogi N, Nugent M, Duck SA, Kirkwood A, Chavez-Valdez R
International journal of molecular sciences 2022 Dec 28;24(1)
International journal of molecular sciences 2022 Dec 28;24(1)
Postmortem 7T MRI for guided histopathology and evaluation of cerebrovascular disease.
Lahna D, Roese N, Woltjer R, Boespflug EL, Schwartz D, Grinstead J, Dodge HH, Wall R, Kaye JA, Rooney WD, Silbert LC
Journal of neuropathology and experimental neurology 2022 Dec 19;82(1):57-70
Journal of neuropathology and experimental neurology 2022 Dec 19;82(1):57-70
Melatonin attenuates bone cancer pain via the SIRT1/HMGB1 pathway.
Yang C, Kang F, Huang X, Zhang W, Wang S, Han M, Zhang Z, Li J
Neuropharmacology 2022 Dec 1;220:109254
Neuropharmacology 2022 Dec 1;220:109254
RSL3 triggers glioma stem cell differentiation via the Tgm2/AKT/ID1 signaling axis.
Li M, Song D, Chen X, Wang X, Xu L, Yang M, Yang J, Kalvakolanu DV, Wei X, Liu X, Li Y, Guo B, Zhang L
Biochimica et biophysica acta. Molecular basis of disease 2022 Dec 1;1868(12):166529
Biochimica et biophysica acta. Molecular basis of disease 2022 Dec 1;1868(12):166529
Gold Nanostrip Array-Mediated Wireless Electrical Stimulation for Accelerating Functional Neuronal Differentiation.
Yang H, Su Y, Sun Z, Ma B, Liu F, Kong Y, Sun C, Li B, Sang Y, Wang S, Li G, Qiu J, Liu C, Geng Z, Liu H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Aug;9(22):e2202376
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Aug;9(22):e2202376
EMMPRIN Promotes the Expression of MMP-9 and Exacerbates Neurological Dysfunction in a Mouse Model of Intracerebral Hemorrhage.
Liu Y, Bai Q, Yong VW, Xue M
Neurochemical research 2022 Aug;47(8):2383-2395
Neurochemical research 2022 Aug;47(8):2383-2395
Taurine supplementation improves hippocampal metabolism in immature rats with intrauterine growth restriction (IUGR) through protecting neurons and reducing gliosis.
Fang Q, Liu J, Chen L, Chen Q, Wang Y, Li Z, Fu W, Liu Y
Metabolic brain disease 2022 Aug;37(6):2077-2088
Metabolic brain disease 2022 Aug;37(6):2077-2088
Preventive effects of arctigenin from Arctium lappa L against LPS-induced neuroinflammation and cognitive impairments in mice.
Yuan Q, Wu Y, Wang G, Zhou X, Dong X, Lou Z, Li S, Wang D
Metabolic brain disease 2022 Aug;37(6):2039-2052
Metabolic brain disease 2022 Aug;37(6):2039-2052
Focused ultrasound/microbubbles-assisted BBB opening enhances LNP-mediated mRNA delivery to brain.
Ogawa K, Kato N, Yoshida M, Hiu T, Matsuo T, Mizukami S, Omata D, Suzuki R, Maruyama K, Mukai H, Kawakami S
Journal of controlled release : official journal of the Controlled Release Society 2022 Aug;348:34-41
Journal of controlled release : official journal of the Controlled Release Society 2022 Aug;348:34-41
Construction and identification of an immortalized rat intestinal smooth muscle cell line.
Chen H, Li X, Gao L, Zhang D, Han T
Neurogastroenterology and motility 2022 Aug;34(8):e14359
Neurogastroenterology and motility 2022 Aug;34(8):e14359
The contribution of proteasomal impairment to autophagy activation by C9orf72 poly-GA aggregates.
Pu M, Tai Y, Yuan L, Zhang Y, Guo H, Hao Z, Chen J, Qi X, Wang G, Tao Z, Ren J
Cellular and molecular life sciences : CMLS 2022 Aug 29;79(9):501
Cellular and molecular life sciences : CMLS 2022 Aug 29;79(9):501
Gene delivery of chitosan-graft-polyethyleneimine vectors loaded on scaffolds for nerve regeneration.
Wang Y, Li Y, Huang Z, Yang B, Mu N, Yang Z, Deng M, Liao X, Yin G, Nie Y, Chen T, Ma H
Carbohydrate polymers 2022 Aug 15;290:119499
Carbohydrate polymers 2022 Aug 15;290:119499
A non-invasive system to monitor in vivo neural graft activity after spinal cord injury.
Ago K, Nagoshi N, Imaizumi K, Kitagawa T, Kawai M, Kajikawa K, Shibata R, Kamata Y, Kojima K, Shinozaki M, Kondo T, Iwano S, Miyawaki A, Ohtsuka M, Bito H, Kobayashi K, Shibata S, Shindo T, Kohyama J, Matsumoto M, Nakamura M, Okano H
Communications biology 2022 Aug 10;5(1):803
Communications biology 2022 Aug 10;5(1):803
Maresin 1 improves cognitive decline and ameliorates inflammation and blood-brain barrier damage in rats with chronic cerebral hypoperfusion.
Li T, Zheng J, Wang Z, Xu L, Sun D, Song H, Wu S, Du M, Peng S, Zhang J
Brain research 2022 Aug 1;1788:147936
Brain research 2022 Aug 1;1788:147936
Maternal stress programs a demasculinization of glutamatergic transmission in stress-related brain regions of aged rats.
Verhaeghe R, Gao V, Morley-Fletcher S, Bouwalerh H, Van Camp G, Cisani F, Nicoletti F, Maccari S
GeroScience 2022 Apr;44(2):1047-1069
GeroScience 2022 Apr;44(2):1047-1069
Stemness Maintenance and Massproduction of Neural Stem Cells on Poly L-Lactic Acid Nanofibrous Membrane Based on Piezoelectriceffect.
Lu X, Sun C, Chen L, Feng Z, Gao H, Hu S, Dong M, Wang J, Zhou W, Ren N, Zhou H, Liu H
Small (Weinheim an der Bergstrasse, Germany) 2022 Apr;18(13):e2107236
Small (Weinheim an der Bergstrasse, Germany) 2022 Apr;18(13):e2107236
Cannabidiol prevents depressive-like behaviors through the modulation of neural stem cell differentiation.
Hou M, Wang S, Yu D, Lu X, Zhao X, Chen Z, Yan C
Frontiers of medicine 2022 Apr;16(2):227-239
Frontiers of medicine 2022 Apr;16(2):227-239
NLRP3 inflammasome of microglia promotes A1 astrocyte transformation, neo-neuron decline and cognition impairment in endotoxemia.
Xiao T, Ji H, Shangguan X, Qu S, Cui Y, Xu J
Biochemical and biophysical research communications 2022 Apr 30;602:1-7
Biochemical and biophysical research communications 2022 Apr 30;602:1-7
Intranasal Administration of Agomir-let-7i Improves Cognitive Function in Mice with Traumatic Brain Injury.
He XC, Wang J, Du HZ, Liu CM, Teng ZQ
Cells 2022 Apr 15;11(8)
Cells 2022 Apr 15;11(8)
Profiling of Sexually Dimorphic Genes in Neural Cells to Identify Eif2s3y, Whose Overexpression Causes Autism-Like Behaviors in Male Mice.
Zhang M, Zhou Y, Jiang Y, Lu Z, Xiao X, Ning J, Sun H, Zhang X, Luo H, Can D, Lu J, Xu H, Zhang YW
Frontiers in cell and developmental biology 2021;9:669798
Frontiers in cell and developmental biology 2021;9:669798
Oridonin Alleviates LPS-Induced Depression by Inhibiting NLRP3 Inflammasome via Activation of Autophagy.
Li C, Zhu Y, Wu Y, Fu M, Wu Y, Wu Y, Qiu Y, Zhang H, Ding M
Frontiers in medicine 2021;8:813047
Frontiers in medicine 2021;8:813047
Gut Microbiota Disorders Promote Inflammation and Aggravate Spinal Cord Injury Through the TLR4/MyD88 Signaling Pathway.
Rong Z, Huang Y, Cai H, Chen M, Wang H, Liu G, Zhang Z, Wu J
Frontiers in nutrition 2021;8:702659
Frontiers in nutrition 2021;8:702659
Neuroprotective Effect of Ceftriaxone on MPTP-Induced Parkinson's Disease Mouse Model by Regulating Inflammation and Intestinal Microbiota.
Zhou X, Lu J, Wei K, Wei J, Tian P, Yue M, Wang Y, Hong D, Li F, Wang B, Chen T, Fang X
Oxidative medicine and cellular longevity 2021;2021:9424582
Oxidative medicine and cellular longevity 2021;2021:9424582
Combined Use of Chitosan and Olfactory Mucosa Mesenchymal Stem/Stromal Cells to Promote Peripheral Nerve Regeneration In Vivo.
Alvites RD, Branquinho MV, Sousa AC, Amorim I, Magalhães R, João F, Almeida D, Amado S, Prada J, Pires I, Zen F, Raimondo S, Luís AL, Geuna S, Varejão ASP, Maurício AC
Stem cells international 2021;2021:6613029
Stem cells international 2021;2021:6613029
The Role of Exercise in Reducing Hyperlipidemia-Induced Neuronal Damage in Apolipoprotein E-Deficient Mice.
Bai Y, Feng Y, Jiang B, Yang Y, Pei Z, Yang Q, Cui Y
BioMed research international 2021;2021:5512518
BioMed research international 2021;2021:5512518
Dl-3-n-Butylphthalide Reduces Cognitive Deficits and Alleviates Neuropathology in P301S Tau Transgenic Mice.
Chang Y, Yao Y, Ma R, Wang Z, Hu J, Wu Y, Jiang X, Li L, Li G
Frontiers in neuroscience 2021;15:620176
Frontiers in neuroscience 2021;15:620176
Alteration of N (6) -Methyladenosine mRNA Methylation in a Rat Model of Cerebral Ischemia-Reperfusion Injury.
Yi D, Wang Q, Zhao Y, Song Y, You H, Wang J, Liu R, Shi Z, Chen X, Luo Q
Frontiers in neuroscience 2021;15:605654
Frontiers in neuroscience 2021;15:605654
Dl-3-n-Butylphthalide Rescues Dopaminergic Neurons in Parkinson's Disease Models by Inhibiting the NLRP3 Inflammasome and Ameliorating Mitochondrial Impairment.
Que R, Zheng J, Chang Z, Zhang W, Li H, Xie Z, Huang Z, Wang HT, Xu J, Jin D, Yang W, Tan EK, Wang Q
Frontiers in immunology 2021;12:794770
Frontiers in immunology 2021;12:794770
Fascin-1 is Highly Expressed Specifically in Microglia After Spinal Cord Injury and Regulates Microglial Migration.
Yu S, Cheng L, Tian D, Li Z, Yao F, Luo Y, Liu Y, Zhu Z, Zheng M, Jing J
Frontiers in pharmacology 2021;12:729524
Frontiers in pharmacology 2021;12:729524
Resveratrol Alleviates Levodopa-Induced Dyskinesia in Rats.
Zheng CQ, Fan HX, Li XX, Li JJ, Sheng S, Zhang F
Frontiers in immunology 2021;12:683577
Frontiers in immunology 2021;12:683577
Catalytic patch with redox Cr/CeO(2) nanozyme of noninvasive intervention for brain trauma.
Zhang S, Liu Y, Sun S, Wang J, Li Q, Yan R, Gao Y, Liu H, Liu S, Hao W, Dai H, Liu C, Sun Y, Long W, Mu X, Zhang XD
Theranostics 2021;11(6):2806-2821
Theranostics 2021;11(6):2806-2821
Edaravone attenuates cadmium-induced toxicity by inhibiting oxidative stress and inflammation in ICR mice.
Fan SR, Ren TT, Yun MY, Lan R, Qin XY
Neurotoxicology 2021 Sep;86:1-9
Neurotoxicology 2021 Sep;86:1-9
The Long Non-coding RNA NEAT1/miR-224-5p/IL-33 Axis Modulates Macrophage M2a Polarization and A1 Astrocyte Activation.
Liu D, Wei Y, Liu Y, Wu T, Hu J, Lu H
Molecular neurobiology 2021 Sep;58(9):4506-4519
Molecular neurobiology 2021 Sep;58(9):4506-4519
Lack of Mof reduces acute liver injury by enhancing transcriptional activation of Igf1.
Wang M, Liu H, Zhang X, Zhao W, Li D, Xu C, Wu Z, Xie F, Li X
Journal of cellular physiology 2021 Sep;236(9):6559-6570
Journal of cellular physiology 2021 Sep;236(9):6559-6570
Utilizing the Faxitron MultiRad 225 X-ray irradiation system for the construction of mouse chronic whole brain radiation model.
He Y, Peng Y, Chang Y, Zhu J, Li Z, Huang K, Pan S
Journal of radiation research 2021 Sep 28;
Journal of radiation research 2021 Sep 28;
Overexpression of miR-338-5p in exosomes derived from mesenchymal stromal cells provides neuroprotective effects by the Cnr1/Rap1/Akt pathway after spinal cord injury in rats.
Zhang A, Bai Z, Yi W, Hu Z, Hao J
Neuroscience letters 2021 Sep 14;761:136124
Neuroscience letters 2021 Sep 14;761:136124
Ketamine ameliorates depressive-like behaviors in mice through increasing glucose uptake regulated by the ERK/GLUT3 signaling pathway.
Ouyang X, Wang Z, Luo M, Wang M, Liu X, Chen J, Feng J, Jia J, Wang X
Scientific reports 2021 Sep 13;11(1):18181
Scientific reports 2021 Sep 13;11(1):18181
Sleep disturbance induces depressive behaviors and neuroinflammation by altering the circadian oscillations of clock genes in rats.
Xing C, Zhou Y, Xu H, Ding M, Zhang Y, Zhang M, Hu M, Huang X, Song L
Neuroscience research 2021 Oct;171:124-132
Neuroscience research 2021 Oct;171:124-132
Inhibition of sEH via stabilizing the level of EETs alleviated Alzheimer's disease through GSK3β signaling pathway.
Sun CP, Zhang XY, Zhou JJ, Huo XK, Yu ZL, Morisseau C, Hammock BD, Ma XC
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Oct;156:112516
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Oct;156:112516
Astrocytic Kir4.1 regulates NMDAR/calpain signaling axis in lipopolysaccharide-induced depression-like behaviors in mice.
Song Z, Bian Z, Zhang Z, Wang X, Zhu A, Zhu G
Toxicology and applied pharmacology 2021 Oct 15;429:115711
Toxicology and applied pharmacology 2021 Oct 15;429:115711
Aluminum impairs cognitive function by activating DDX3X-NLRP3-mediated pyroptosis signaling pathway.
Hao W, Hao C, Wu C, Xu Y, Wu S, Lu X, Yang J, Jin C
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Nov;157:112591
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Nov;157:112591
Vagus nerve stimulation mediates microglia M1/2 polarization via inhibition of TLR4 pathway after ischemic stroke.
Zhang L, Liu Y, Wang S, Long L, Zang Q, Ma J, Yu L, Jia G
Biochemical and biophysical research communications 2021 Nov 5;577:71-79
Biochemical and biophysical research communications 2021 Nov 5;577:71-79
Deficiency of cGAS signaling protects against sepsis-associated encephalopathy.
Tan C, Xu F, Xie Q, Li F
Biochemical and biophysical research communications 2021 Nov 5;577:38-44
Biochemical and biophysical research communications 2021 Nov 5;577:38-44
The seed oil of Paeonia ludlowii ameliorates Aβ25-35-induced Alzheimer's disease in rats.
Lu YZ, Zhang CQ, Yu BX, Zhang EH, Quan H, Yin X, Cai H, Yuan F, Li LQ, Xu YJ, Su YJ, Xing YJ, Liao ZH, Lan XZ
Food science & nutrition 2021 May;9(5):2402-2413
Food science & nutrition 2021 May;9(5):2402-2413
Proteomic analysis of aged and OPTN E50K retina in the development of normal tension glaucoma.
Liu X, Wang Q, Shao Z, Zhang S, Hou M, Jiang M, Du M, Li J, Yuan H
Human molecular genetics 2021 May 31;30(11):1030-1044
Human molecular genetics 2021 May 31;30(11):1030-1044
A diet high in sugar and fat influences neurotransmitter metabolism and then affects brain function by altering the gut microbiota.
Guo Y, Zhu X, Zeng M, Qi L, Tang X, Wang D, Zhang M, Xie Y, Li H, Yang X, Chen D
Translational psychiatry 2021 May 27;11(1):328
Translational psychiatry 2021 May 27;11(1):328
Activation of FXR by ganoderic acid A promotes remyelination in multiple sclerosis via anti-inflammation and regeneration mechanism.
Jia Y, Zhang D, Li H, Luo S, Xiao Y, Han L, Zhou F, Wang C, Feng L, Wang G, Wu P, Xiao C, Yu H, Du J, Bao H
Biochemical pharmacology 2021 Mar;185:114422
Biochemical pharmacology 2021 Mar;185:114422
A five-m6A regulatory gene signature is a prognostic biomarker in lung adenocarcinoma patients.
Wu X, Sheng H, Wang L, Xia P, Wang Y, Yu L, Lv W, Hu J
Aging 2021 Mar 26;13(7):10034-10057
Aging 2021 Mar 26;13(7):10034-10057
Modulation of the HMGB1/TLR4/NF-κB signaling pathway in the CNS by matrine in experimental autoimmune encephalomyelitis.
Chu Y, Jing Y, Zhao X, Wang M, Zhang M, Ma R, Ma W, Lv Y, Zhu L
Journal of neuroimmunology 2021 Mar 15;352:577480
Journal of neuroimmunology 2021 Mar 15;352:577480
Taurine improves the differentiation of neural stem cells in fetal rats with intrauterine growth restriction via activation of the PKA-CREB-BDNF signaling pathway.
Fang Q, Liu J, Chen L, Chen Q, Ke J, Zhang J, Liu Y, Fu W
Metabolic brain disease 2021 Jun;36(5):969-981
Metabolic brain disease 2021 Jun;36(5):969-981
Ganoderma lucidum polysaccharides ameliorated depression-like behaviors in the chronic social defeat stress depression model via modulation of Dectin-1 and the innate immune system.
Li H, Xiao Y, Han L, Jia Y, Luo S, Zhang D, Zhang L, Wu P, Xiao C, Kan W, Du J, Bao H
Brain research bulletin 2021 Jun;171:16-24
Brain research bulletin 2021 Jun;171:16-24
Translation of GGC repeat expansions into a toxic polyglycine protein in NIID defines a novel class of human genetic disorders: The polyG diseases.
Boivin M, Deng J, Pfister V, Grandgirard E, Oulad-Abdelghani M, Morlet B, Ruffenach F, Negroni L, Koebel P, Jacob H, Riet F, Dijkstra AA, McFadden K, Clayton WA, Hong D, Miyahara H, Iwasaki Y, Sone J, Wang Z, Charlet-Berguerand N
Neuron 2021 Jun 2;109(11):1825-1835.e5
Neuron 2021 Jun 2;109(11):1825-1835.e5
A Novel Rat Model with Long Range Optic Nerve Injury to Study Retinal Ganglion Cells Endogenous Regeneration.
Zhang S, Liu B, Zhu H, Jin H, Gong Z, Qiu H, Xu M, Chen M, Nan K, Wu W
Neuroscience 2021 Jun 15;465:71-84
Neuroscience 2021 Jun 15;465:71-84
Edaravone attenuates H(2)O(2) or glutamate-induced toxicity in hippocampal neurons and improves AlCl(3)/D-galactose induced cognitive impairment in mice.
Wu HT, Yu Y, Li XX, Lang XY, Gu RZ, Fan SR, Fang X, Bai JP, Lan R, Qin XY
Neurotoxicology 2021 Jul;85:68-78
Neurotoxicology 2021 Jul;85:68-78
Effect of the interference with DRP1 expression on the biological characteristics of glioma stem cells.
Zhang L, Cao H, Tao H, Yang J, Gong W, Hu Q
Experimental and therapeutic medicine 2021 Jul;22(1):696
Experimental and therapeutic medicine 2021 Jul;22(1):696
Resveratrol attenuates manganese-induced oxidative stress and neuroinflammation through SIRT1 signaling in mice.
Cong L, Lei MY, Liu ZQ, Liu ZF, Ma Z, Liu K, Li J, Deng Y, Liu W, Xu B
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Jul;153:112283
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Jul;153:112283
C-phycocyanin Mitigates Cognitive Impairment in Doxorubicin-Induced Chemobrain: Impact on Neuroinflammation, Oxidative Stress, and Brain Mitochondrial and Synaptic Alterations.
Wang C, Zhao Y, Wang L, Pan S, Liu Y, Li S, Wang D
Neurochemical research 2021 Feb;46(2):149-158
Neurochemical research 2021 Feb;46(2):149-158
Effects of the histone acetylase inhibitor C646 on growth and differentiation of adipose-derived stem cells.
Wang Z, Wang X, Bi M, Hu X, Wang Q, Liang H, Liu D
Cell cycle (Georgetown, Tex.) 2021 Feb;20(4):392-405
Cell cycle (Georgetown, Tex.) 2021 Feb;20(4):392-405
Parvalbumin interneuron-mediated neural disruption in an animal model of postintensive care syndrome: prevention by fluoxetine.
Wang Y, Yin XY, He X, Zhou CM, Shen JC, Tong JH
Aging 2021 Feb 22;13(6):8720-8736
Aging 2021 Feb 22;13(6):8720-8736
Annexin A1 Attenuates Neutrophil Migration and IL-6 Expression through Fpr2 in a Mouse Model of Streptococcus suis-Induced Meningitis.
Ni C, Gao S, Zheng Y, Liu P, Zhai Y, Huang W, Jiang H, Lv Q, Kong D, Jiang Y
Infection and immunity 2021 Feb 16;89(3)
Infection and immunity 2021 Feb 16;89(3)
Dicer1 promotes Aβ clearance via blocking B2 RNA-mediated repression of apolipoprotein E.
Wang Y, Lian M, Xiu X, Zhang Z, Song L, Wu S
Biochimica et biophysica acta. Molecular basis of disease 2021 Feb 1;1867(2):166038
Biochimica et biophysica acta. Molecular basis of disease 2021 Feb 1;1867(2):166038
Gisenoside Rg1 attenuates cadmium-induced neurotoxicity in vitro and in vivo by attenuating oxidative stress and inflammation.
Ren TT, Yang JY, Wang J, Fan SR, Lan R, Qin XY
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2021 Dec;70(10-12):1151-1164
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2021 Dec;70(10-12):1151-1164
Flow cytometry analysis of immune and glial cells in a trigeminal neuralgia rat model.
Lin J, Zhou L, Luo Z, Adam MI, Zhao L, Wang F, Luo D
Scientific reports 2021 Dec 7;11(1):23569
Scientific reports 2021 Dec 7;11(1):23569
Astaxanthin alleviates neuropathic pain by inhibiting the MAPKs and NF-κB pathways.
Zhao L, Tao X, Song T
European journal of pharmacology 2021 Dec 5;912:174575
European journal of pharmacology 2021 Dec 5;912:174575
Proinflammatory Pathways Are Activated in the Human Q344X Rhodopsin Knock-In Mouse Model of Retinitis Pigmentosa.
Hollingsworth TJ, Hubbard MG, Levi HJ, White W, Wang X, Simpson R, Jablonski MM, Gross AK
Biomolecules 2021 Aug 6;11(8)
Biomolecules 2021 Aug 6;11(8)
Phytogalactolipid dLGG Inhibits Mouse Melanoma Brain Metastasis through Regulating Oxylipin Activity and Re-Programming Macrophage Polarity in the Tumor Microenvironment.
Yang CC, Chang MT, Chang CK, Shyur LF
Cancers 2021 Aug 16;13(16)
Cancers 2021 Aug 16;13(16)
Melatonin prevents diabetes-associated cognitive dysfunction from microglia-mediated neuroinflammation by activating autophagy via TLR4/Akt/mTOR pathway.
Cui Y, Yang M, Wang Y, Ren J, Lin P, Cui C, Song J, He Q, Hu H, Wang K, Sun Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Apr;35(4):e21485
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Apr;35(4):e21485
Reduction of Autophagosome Overload Attenuates Neuronal Cell Death After Traumatic Brain Injury.
Quan X, Song L, Zheng X, Liu S, Ding H, Li S, Xu G, Li X, Liu L
Neuroscience 2021 Apr 15;460:107-119
Neuroscience 2021 Apr 15;460:107-119
Chemogenetic Activation of CX3CR1-Expressing Spinal Microglia Using Gq-DREADD Elicits Mechanical Allodynia in Male Mice.
Saika F, Matsuzaki S, Kishioka S, Kiguchi N
Cells 2021 Apr 12;10(4)
Cells 2021 Apr 12;10(4)
Involvement of Oxytocin Receptor/Erk/MAPK Signaling in the mPFC in Early Life Stress-Induced Autistic-Like Behaviors.
Wei J, Ma L, Ju P, Yang B, Wang YX, Chen J
Frontiers in cell and developmental biology 2020;8:564485
Frontiers in cell and developmental biology 2020;8:564485
Cdk5 Inhibitory Peptide Prevents Loss of Neurons and Alleviates Behavioral Changes in p25 Transgenic Mice.
Huang Y, Huang W, Huang Y, Song P, Zhang M, Zhang HT, Pan S, Hu Y
Journal of Alzheimer's disease : JAD 2020;74(4):1231-1242
Journal of Alzheimer's disease : JAD 2020;74(4):1231-1242
SerpinA3N deficiency deteriorates impairments of learning and memory in mice following hippocampal stab injury.
Wang ZM, Liu C, Wang YY, Deng YS, He XC, Du HZ, Liu CM, Teng ZQ
Cell death discovery 2020;6(1):88
Cell death discovery 2020;6(1):88
Ginsenoside-Rg1 Rescues Stress-Induced Depression-Like Behaviors via Suppression of Oxidative Stress and Neural Inflammation in Rats.
Li Y, Wang L, Wang P, Fan C, Zhang P, Shen J, Yu SY
Oxidative medicine and cellular longevity 2020;2020:2325391
Oxidative medicine and cellular longevity 2020;2020:2325391
The Protective Effect of Adiponectin-Transfected Endothelial Progenitor Cells on Cognitive Function in D-Galactose-Induced Aging Rats.
Huang J, Hou B, Zhang S, Wang M, Lu X, Wang Q, Liu Y
Neural plasticity 2020;2020:1273198
Neural plasticity 2020;2020:1273198
Biological and Proteomic Characteristics of an Immortalized Human Pancreatic Stellate Cell Line.
Sun L, Qu L, Brigstock DR, Li H, Li Y, Gao R
International journal of medical sciences 2020;17(1):137-144
International journal of medical sciences 2020;17(1):137-144
RNA-seq analysis of gene expression profiles in isolated stria vascularis from wild-type and Alport mice reveals key pathways underling Alport strial pathogenesis.
Dufek B, Meehan DT, Delimont D, Wilhelm K, Samuelson G, Coenen R, Madison J, Doyle E, Smyth B, Phillips G, Gratton MA, Cosgrove D
PloS one 2020;15(8):e0237907
PloS one 2020;15(8):e0237907
Prolonged inflammation leads to ongoing damage after spinal cord injury.
Kwiecien JM, Dabrowski W, Dąbrowska-Bouta B, Sulkowski G, Oakden W, Kwiecien-Delaney CJ, Yaron JR, Zhang L, Schutz L, Marzec-Kotarska B, Stanisz GJ, Karis JP, Struzynska L, Lucas AR
PloS one 2020;15(3):e0226584
PloS one 2020;15(3):e0226584
Resveratrol Preincubation Enhances the Therapeutic Efficacy of hUC-MSCs by Improving Cell Migration and Modulating Neuroinflammation Mediated by MAPK Signaling in a Mouse Model of Alzheimer's Disease.
Wang X, Wu J, Ma S, Xie Y, Liu H, Yao M, Zhang Y, Yang GL, Yang B, Guo R, Guan F
Frontiers in cellular neuroscience 2020;14:62
Frontiers in cellular neuroscience 2020;14:62
Olanzapine-Induced Activation of Hypothalamic Astrocytes and Toll-Like Receptor-4 Signaling via Endoplasmic Reticulum Stress Were Related to Olanzapine-Induced Weight Gain.
He M, Qian K, Zhang Y, Huang XF, Deng C, Zhang B, Gao G, Li J, Xie H, Sun T
Frontiers in neuroscience 2020;14:589650
Frontiers in neuroscience 2020;14:589650
N-Acetylcysteine Rescues Hippocampal Oxidative Stress-Induced Neuronal Injury via Suppression of p38/JNK Signaling in Depressed Rats.
Fan C, Long Y, Wang L, Liu X, Liu Z, Lan T, Li Y, Yu SY
Frontiers in cellular neuroscience 2020;14:554613
Frontiers in cellular neuroscience 2020;14:554613
Time-Dependent Impairment of Fear Conditioning and Associated Brain Regions After Pilocarpine-Induced Status Epilepticus.
Qiu X, Kinoshita M, Peng A, Li W, Lai W, Wang J, Zhang L, Chen L
Frontiers in behavioral neuroscience 2020;14:149
Frontiers in behavioral neuroscience 2020;14:149
Dl-3-n-Butylphthalide Promotes Remyelination and Suppresses Inflammation by Regulating AMPK/SIRT1 and STAT3/NF-κB Signaling in Chronic Cerebral Hypoperfusion.
Li M, Meng N, Guo X, Niu X, Zhao Z, Wang W, Xie X, Lv P
Frontiers in aging neuroscience 2020;12:137
Frontiers in aging neuroscience 2020;12:137
Chemogenetic Regulation of CX3CR1-Expressing Microglia Using Gi-DREADD Exerts Sex-Dependent Anti-Allodynic Effects in Mouse Models of Neuropathic Pain.
Saika F, Matsuzaki S, Kobayashi D, Ideguchi Y, Nakamura TY, Kishioka S, Kiguchi N
Frontiers in pharmacology 2020;11:925
Frontiers in pharmacology 2020;11:925
C-X-C Motif Chemokine 10 Contributes to the Development of Neuropathic Pain by Increasing the Permeability of the Blood-Spinal Cord Barrier.
Li HL, Huang Y, Zhou YL, Teng RH, Zhou SZ, Lin JP, Yang Y, Zhu SM, Xu H, Yao YX
Frontiers in immunology 2020;11:477
Frontiers in immunology 2020;11:477
Neuroprotective Effects of Fluoxetine Against Chronic Stress-Induced Neural Inflammation and Apoptosis: Involvement of the p38 Activity.
Zhao Y, Shang P, Wang M, Xie M, Liu J
Frontiers in physiology 2020;11:351
Frontiers in physiology 2020;11:351
Knockdown of TXNDC9 induces apoptosis and autophagy in glioma and mediates cell differentiation by p53 activation.
Zheng T, Chen K, Zhang X, Feng H, Shi Y, Liu L, Zhang J, Chen Y
Aging 2020 Sep 8;12(18):18649-18659
Aging 2020 Sep 8;12(18):18649-18659
Cell therapy for spinal cord injury by using human iPSC-derived region-specific neural progenitor cells.
Kajikawa K, Imaizumi K, Shinozaki M, Shibata S, Shindo T, Kitagawa T, Shibata R, Kamata Y, Kojima K, Nagoshi N, Matsumoto M, Nakamura M, Okano H
Molecular brain 2020 Sep 3;13(1):120
Molecular brain 2020 Sep 3;13(1):120
Obesity Worsens Gulf War Illness Symptom Persistence Pathology by Linking Altered Gut Microbiome Species to Long-Term Gastrointestinal, Hepatic, and Neuronal Inflammation in a Mouse Model.
Bose D, Saha P, Mondal A, Fanelli B, Seth RK, Janulewicz P, Sullivan K, Lasley S, Horner R, Colwell RR, Shetty AK, Klimas N, Chatterjee S
Nutrients 2020 Sep 10;12(9)
Nutrients 2020 Sep 10;12(9)
Neural network disturbance in the medial prefrontal cortex might contribute to cognitive impairments induced by neuroinflammation.
Ji MH, Lei L, Gao DP, Tong JH, Wang Y, Yang JJ
Brain, behavior, and immunity 2020 Oct;89:133-144
Brain, behavior, and immunity 2020 Oct;89:133-144
Liraglutide Up-regulation Thioredoxin Attenuated Müller Cells Apoptosis in High Glucose by Regulating Oxidative Stress and Endoplasmic Reticulum Stress.
Ren X, Sun L, Wei L, Liu J, Zhu J, Yu Q, Kong H, Kong L
Current eye research 2020 Oct;45(10):1283-1291
Current eye research 2020 Oct;45(10):1283-1291
Caspase inhibition rescues F1Fo ATP synthase dysfunction-mediated dendritic spine elimination.
Chen H, Tian J, Guo L, Du H
Scientific reports 2020 Oct 16;10(1):17589
Scientific reports 2020 Oct 16;10(1):17589
Loss of TDP-43 in astrocytes leads to motor deficits by triggering A1-like reactive phenotype and triglial dysfunction.
Peng AYT, Agrawal I, Ho WY, Yen YC, Pinter AJ, Liu J, Phua QXC, Koh KB, Chang JC, Sanford E, Man JHK, Wong P, Gutmann DH, Tucker-Kellogg G, Ling SC
Proceedings of the National Academy of Sciences of the United States of America 2020 Nov 17;117(46):29101-29112
Proceedings of the National Academy of Sciences of the United States of America 2020 Nov 17;117(46):29101-29112
Non-neuronal crosstalk promotes an inflammatory response in nodose ganglia cultures after exposure to byproducts from gram positive, high-fat-diet-associated gut bacteria.
Cawthon CR, Kirkland RA, Pandya S, Brinson NA, de La Serre CB
Physiology & behavior 2020 Nov 1;226:113124
Physiology & behavior 2020 Nov 1;226:113124
Inhibition of the NLRP3-inflammasome prevents cognitive deficits in experimental autoimmune encephalomyelitis mice via the alteration of astrocyte phenotype.
Hou B, Zhang Y, Liang P, He Y, Peng B, Liu W, Han S, Yin J, He X
Cell death & disease 2020 May 15;11(5):377
Cell death & disease 2020 May 15;11(5):377
Cathodal tDCS exerts neuroprotective effect in rat brain after acute ischemic stroke.
Zhang KY, Rui G, Zhang JP, Guo L, An GZ, Lin JJ, He W, Ding GR
BMC neuroscience 2020 May 12;21(1):21
BMC neuroscience 2020 May 12;21(1):21
Effect of AQP4-RNAi in treating traumatic brain edema: Multi-modal MRI and histopathological changes of early stage edema in a rat model.
Guan Y, Li L, Chen J, Lu H
Experimental and therapeutic medicine 2020 Mar;19(3):2029-2036
Experimental and therapeutic medicine 2020 Mar;19(3):2029-2036
Carbon dot targeting to nitrogen signaling molecules for inhibiting neuronal death.
Ouyang L, Mu X, Wang J, Li Q, Gao Y, Liu H, Sun S, Ren Q, Yan R, Wang J, Liu Q, Sun Y, Liu C, He H, Long W, Zhang XD
Journal of materials chemistry. B 2020 Mar 18;8(11):2321-2330
Journal of materials chemistry. B 2020 Mar 18;8(11):2321-2330
Ghrelin promotes neural differentiation of adipose tissue-derived mesenchymal stem cell via AKT/mTOR and β-catenin signaling pathways.
Liu GB, Pan YM, Liu YS, Hu JH, Zhang XD, Zhang DW, Wang Y, Feng YK, Yu JB, Cheng YX
The Kaohsiung journal of medical sciences 2020 Jun;36(6):405-416
The Kaohsiung journal of medical sciences 2020 Jun;36(6):405-416
The effect of swimming exercise and diet on the hypothalamic inflammation of ApoE-/- mice based on SIRT1-NF-κB-GnRH expression.
Wang X, Yang J, Lu T, Zhan Z, Wei W, Lyu X, Jiang Y, Xue X
Aging 2020 Jun 9;12(11):11085-11099
Aging 2020 Jun 9;12(11):11085-11099
Excretory/secretory products of Angiostrongylus cantonensis fifth-stage larvae induce endoplasmic reticulum stress via the Sonic hedgehog pathway in mouse astrocytes.
Chen KY, Chen YJ, Cheng CJ, Jhan KY, Wang LC
Parasites & vectors 2020 Jun 18;13(1):317
Parasites & vectors 2020 Jun 18;13(1):317
Polydopamine/carboxylic graphene oxide-composited polypyrrole films for promoting adhesion and alignment of Schwann cells.
Li Y, Huang Z, Pu X, Chen X, Yin G, Wang Y, Miao D, Fan J, Mu J
Colloids and surfaces. B, Biointerfaces 2020 Jul;191:110972
Colloids and surfaces. B, Biointerfaces 2020 Jul;191:110972
Protection of the Geum japonicum Thunb. var. chinense extracts against oxygen-glucose deprivation and re-oxygenation induced astrocytes injury via BDNF/PI3K/Akt/CREB pathway.
Du L, Mei Z, Huang Y, Tao W, Wang K, Huang W, Zhou H, Feng Z
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jul;127:110123
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jul;127:110123
Scorpion alleviates bone cancer pain through inhibition of bone destruction and glia activation.
Yu J, Luo Y, Jin H, Lv J, Zhou T, Yabasin IB, Wen Q
Molecular pain 2020 Jan-Dec;16:1744806920909993
Molecular pain 2020 Jan-Dec;16:1744806920909993
Elevated lymphocyte specific protein 1 expression is involved in the regulation of leukocyte migration and immunosuppressive microenvironment in glioblastoma.
Cao JY, Guo Q, Guan GF, Zhu C, Zou CY, Zhang LY, Cheng W, Wang GL, Cheng P, Wu AH, Li GY
Aging 2020 Jan 29;12(2):1656-1684
Aging 2020 Jan 29;12(2):1656-1684
Neuroinflammation induced by secretion of acetylated HMGB1 from activated microglia in hippocampi of mice following chronic cold exposure.
Xu B, Lang LM, Lian S, Guo JR, Wang JF, Liu J, Yang HM, Li SZ
Brain research 2020 Jan 1;1726:146495
Brain research 2020 Jan 1;1726:146495
Silencing of circular RNA HIPK2 in neural stem cells enhances functional recovery following ischaemic stroke.
Wang G, Han B, Shen L, Wu S, Yang L, Liao J, Wu F, Li M, Leng S, Zang F, Zhang Y, Bai Y, Mao Y, Chen B, Yao H
EBioMedicine 2020 Feb;52:102660
EBioMedicine 2020 Feb;52:102660
Resveratrol Downregulates STAT3 Expression and Astrocyte Activation in Primary Astrocyte Cultures of Rat.
Wu M, Wang L, Li F, Hu R, Ma J, Zhang K, Cheng X
Neurochemical research 2020 Feb;45(2):455-464
Neurochemical research 2020 Feb;45(2):455-464
Effects of circadian rhythm disorder on the hippocampus of SHR and WKY rats.
Wang Y, Zhang Y, Wang W, Liu X, Chi Y, Lei J, Zhang B, Zhang T
Neurobiology of learning and memory 2020 Feb;168:107141
Neurobiology of learning and memory 2020 Feb;168:107141
Photobiomodulation therapy for repeated closed head injury in rats.
Yang B, Xu J, Li Y, Dong Y, Li Y, Tucker L, Yang L, Zong X, Wu C, Xu T, Hu S, Zhang Q, Yan X
Journal of biophotonics 2020 Feb;13(2):e201960117
Journal of biophotonics 2020 Feb;13(2):e201960117
The Pattern of AQP4 Expression in the Ageing Human Brain and in Cerebral Amyloid Angiopathy.
Owasil R, O'Neill R, Keable A, Nimmo J, MacGregor Sharp M, Kelly L, Saito S, Simpson JE, Weller RO, Smith C, Attems J, Wharton SB, Yuen HM, Carare RO
International journal of molecular sciences 2020 Feb 12;21(4)
International journal of molecular sciences 2020 Feb 12;21(4)
GABA-mediated activated microglia induce neuroinflammation in the hippocampus of mice following cold exposure through the NLRP3 inflammasome and NF-κB signaling pathways.
Lang L, Xu B, Yuan J, Li S, Lian S, Chen Y, Guo J, Yang H
International immunopharmacology 2020 Dec;89(Pt B):106908
International immunopharmacology 2020 Dec;89(Pt B):106908
Small molecular compounds efficiently convert human fibroblasts directly into neurons.
Yang J, Cao H, Guo S, Zhu H, Tao H, Zhang L, Chen Z, Sun T, Chi S, Hu Q
Molecular medicine reports 2020 Dec;22(6):4763-4771
Molecular medicine reports 2020 Dec;22(6):4763-4771
Donepezil-induced oligodendrocyte differentiation is mediated through estrogen receptors.
Imamura O, Arai M, Dateki M, Oishi K, Takishima K
Journal of neurochemistry 2020 Dec;155(5):494-507
Journal of neurochemistry 2020 Dec;155(5):494-507
Zika virus promotes CCN1 expression via the CaMKIIα-CREB pathway in astrocytes.
Sun J, Zhang W, Tan Z, Zheng C, Tang Y, Ke X, Zhang Y, Liu Y, Li P, Hu Q, Wang H, Mao P, Zheng Z
Virulence 2020 Dec;11(1):113-131
Virulence 2020 Dec;11(1):113-131
Cryogen spray cooling mitigates inflammation and injury-induced CISD2 decline in rat spinal cord hemisection model.
Kung WM, Chang CJ, Chen TY, Lin MS
Journal of integrative neuroscience 2020 Dec 30;19(4):619-628
Journal of integrative neuroscience 2020 Dec 30;19(4):619-628
Neuroprotective effects and mechanisms of action of nicotinamide mononucleotide (NMN) in a photoreceptor degenerative model of retinal detachment.
Chen X, Amorim JA, Moustafa GA, Lee JJ, Yu Z, Ishihara K, Iesato Y, Barbisan P, Ueta T, Togka KA, Lu L, Sinclair DA, Vavvas DG
Aging 2020 Dec 29;12(24):24504-24521
Aging 2020 Dec 29;12(24):24504-24521
Evaluating the Cytotoxicity of Ti(3)C(2) MXene to Neural Stem Cells.
Wu W, Ge H, Zhang L, Lei X, Yang Y, Fu Y, Feng H
Chemical research in toxicology 2020 Dec 21;33(12):2953-2962
Chemical research in toxicology 2020 Dec 21;33(12):2953-2962
Silencing IFNγ inhibits A1 astrocytes and attenuates neurogenesis decline and cognitive impairment in endotoxemia.
Lu Y, Yang Y, Peng Z, Xie L, Zhong X, Liang F, Yuan C, Lu B
Biochemical and biophysical research communications 2020 Dec 17;533(4):1519-1526
Biochemical and biophysical research communications 2020 Dec 17;533(4):1519-1526
Spider venom components decrease glioblastoma cell migration and invasion through RhoA-ROCK and Na(+)/K(+)-ATPase β2: potential molecular entities to treat invasive brain cancer.
Barreto N, Caballero M, Bonfanti AP, de Mato FCP, Munhoz J, da Rocha-E-Silva TAA, Sutti R, Vitorino-Araujo JL, Verinaud L, Rapôso C
Cancer cell international 2020 Dec 17;20(1):576
Cancer cell international 2020 Dec 17;20(1):576
Perinatal exposure to nonylphenol delayed myelination in offspring cerebellum.
Jiang Y, You M, Li S, Xu Y, Wang Y
Biochemical pharmacology 2020 Aug;178:114120
Biochemical pharmacology 2020 Aug;178:114120
Antidepressant-like Effect of Merazin Hydrate Depends on NO/ERK by Suppressing Its Downstream NF-κB or Nonactivating CREB/BDNF in Mouse Hippocampus.
Wu L, Liu X, Huang Y, Lu C, Zhou J, Ren P, Huang X
ACS chemical neuroscience 2020 Aug 19;11(16):2472-2481
ACS chemical neuroscience 2020 Aug 19;11(16):2472-2481
Upregulation of miRNA-9-5p Promotes Angiogenesis after Traumatic Brain Injury by Inhibiting Ptch-1.
Wu J, He J, Tian X, Li H, Wen Y, Shao Q, Cheng C, Wang G, Sun X
Neuroscience 2020 Aug 1;440:160-174
Neuroscience 2020 Aug 1;440:160-174
PPARα-Dependent Effects of Palmitoylethanolamide Against Retinal Neovascularization and Fibrosis.
Ye S, Chen Q, Jiang N, Liang X, Li J, Zong R, Huang C, Qiu Y, Ma JX, Liu Z
Investigative ophthalmology & visual science 2020 Apr 9;61(4):15
Investigative ophthalmology & visual science 2020 Apr 9;61(4):15
[Establishment of a vimentin knockout and HIV-1 gp120 transgenic mouse model].
He X, Peng L, Zhang B, Li L, Wu C, Xiao H, Yang W, Zeng Z, Yang X, Long M, Cao H, Huang S
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2020 Apr 30;40(4):519-524
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2020 Apr 30;40(4):519-524
Local Serpin Treatment via Chitosan-Collagen Hydrogel after Spinal Cord Injury Reduces Tissue Damage and Improves Neurologic Function.
Kwiecien JM, Zhang L, Yaron JR, Schutz LN, Kwiecien-Delaney CJ, Awo EA, Burgin M, Dabrowski W, Lucas AR
Journal of clinical medicine 2020 Apr 23;9(4)
Journal of clinical medicine 2020 Apr 23;9(4)
Metal ion-responsive nanocarrier derived from phosphonated calix[4]arenes for delivering dauricine specifically to sites of brain injury in a mouse model of intracerebral hemorrhage.
Li M, Liu G, Wang K, Wang L, Fu X, Lim LY, Chen W, Mo J
Journal of nanobiotechnology 2020 Apr 19;18(1):61
Journal of nanobiotechnology 2020 Apr 19;18(1):61
Doxorubicin-polyglycerol-nanodiamond conjugates disrupt STAT3/IL-6-mediated reciprocal activation loop between glioblastoma cells and astrocytes.
Chen Z, Yuan SJ, Li K, Zhang Q, Li TF, An HC, Xu HZ, Yue Y, Han M, Xu YH, Komatsu N, Zhao L, Chen X
Journal of controlled release : official journal of the Controlled Release Society 2020 Apr 10;320:469-483
Journal of controlled release : official journal of the Controlled Release Society 2020 Apr 10;320:469-483
Chlorogenic acid effectively treats cancers through induction of cancer cell differentiation.
Huang S, Wang LL, Xue NN, Li C, Guo HH, Ren TK, Zhan Y, Li WB, Zhang J, Chen XG, Han YX, Zhang JL, Jiang JD
Theranostics 2019;9(23):6745-6763
Theranostics 2019;9(23):6745-6763
Sailuotong Capsule Prevents the Cerebral Ischaemia-Induced Neuroinflammation and Impairment of Recognition Memory through Inhibition of LCN2 Expression.
Zhang Y, Liu J, Yao M, Song W, Zheng Y, Xu L, Sun M, Yang B, Bensoussan A, Chang D, Li H
Oxidative medicine and cellular longevity 2019;2019:8416105
Oxidative medicine and cellular longevity 2019;2019:8416105
C(18)H(17)NO(6) and Its Combination with Scutellarin Suppress the Proliferation and Induce the Apoptosis of Human Glioma Cells via Upregulation of Fas-Associated Factor 1 Expression.
He XY, Xiong LL, Xia QJ, Wang YY, Zhao XM, Du RL, Huang J, He XQ, Jia-Liu, Wang TH
BioMed research international 2019;2019:6821219
BioMed research international 2019;2019:6821219
Decreased immunoglobulin G in brain regions of elder female APOE4-TR mice accompany with Aβ accumulation.
Zhang L, Xu J, Gao J, Chen P, Yin M, Zhao W
Immunity & ageing : I & A 2019;16:2
Immunity & ageing : I & A 2019;16:2
Myelin Damage in Diffuse Axonal Injury.
Mu J, Li M, Wang T, Li X, Bai M, Zhang G, Kong J
Frontiers in neuroscience 2019;13:217
Frontiers in neuroscience 2019;13:217
BAF45D Downregulation in Spinal Cord Ependymal Cells Following Spinal Cord Injury in Adult Rats and Its Potential Role in the Development of Neuronal Lesions.
Wang Z, Huang J, Liu C, Liu L, Shen Y, Shen C, Liu C
Frontiers in neuroscience 2019;13:1151
Frontiers in neuroscience 2019;13:1151
Expression of cysteinyl leukotriene receptor in brain tissues of rats with Streptococcus pneumoniae meningitis.
Yu S, Yan J, Chen X, Zhu X, Li X, Liao L
International journal of clinical and experimental pathology 2019;12(12):4242-4252
International journal of clinical and experimental pathology 2019;12(12):4242-4252
Evidence for Sexual Dimorphism in the Response to TLR3 Activation in the Developing Neonatal Mouse Brain: A Pilot Study.
Chavez-Valdez R, Mottahedin A, Stridh L, Yellowhair TR, Jantzie LL, Northington FJ, Mallard C
Frontiers in physiology 2019;10:306
Frontiers in physiology 2019;10:306
Folic acid improves abnormal behavior via mitigation of oxidative stress, inflammation, and ferroptosis in the BTBR T+ tf/J mouse model of autism.
Zhang Q, Wu H, Zou M, Li L, Li Q, Sun C, Xia W, Cao Y, Wu L
The Journal of nutritional biochemistry 2019 Sep;71:98-109
The Journal of nutritional biochemistry 2019 Sep;71:98-109
Melatonin alleviates cognition impairment by antagonizing brain insulin resistance in aged rats fed a high-fat diet.
Xu J, Gao H, Zhang L, Rong S, Yang W, Ma C, Chen M, Huang Q, Deng Q, Huang F
Journal of pineal research 2019 Sep;67(2):e12584
Journal of pineal research 2019 Sep;67(2):e12584
Ellagic acid supports neuron by regulating astroglia Nrf2.
Wang GQ, He XM, Zhu GF, Li DD, Shi JS, Zhang F
Biotechnology and applied biochemistry 2019 Sep;66(5):738-743
Biotechnology and applied biochemistry 2019 Sep;66(5):738-743
Long non-coding RNA linc00645 promotes TGF-β-induced epithelial-mesenchymal transition by regulating miR-205-3p-ZEB1 axis in glioma.
Li C, Zheng H, Hou W, Bao H, Xiong J, Che W, Gu Y, Sun H, Liang P
Cell death & disease 2019 Sep 26;10(10):717
Cell death & disease 2019 Sep 26;10(10):717
Geraniin Attenuates Lipopolysaccharide-Induced Cognitive Impairment in Mice by Inhibiting Toll-Like Receptor 4 Activation.
Wang D, Dong X, Wang B, Liu Y, Li S
Journal of agricultural and food chemistry 2019 Sep 11;67(36):10079-10088
Journal of agricultural and food chemistry 2019 Sep 11;67(36):10079-10088
Circular RNA TLK1 Aggravates Neuronal Injury and Neurological Deficits after Ischemic Stroke via miR-335-3p/TIPARP.
Wu F, Han B, Wu S, Yang L, Leng S, Li M, Liao J, Wang G, Ye Q, Zhang Y, Chen H, Chen X, Zhong M, Xu Y, Liu Q, Zhang JH, Yao H
The Journal of neuroscience : the official journal of the Society for Neuroscience 2019 Sep 11;39(37):7369-7393
The Journal of neuroscience : the official journal of the Society for Neuroscience 2019 Sep 11;39(37):7369-7393
Activation of mitogen-activated protein kinases in satellite glial cells of the trigeminal ganglion contributes to substance P-mediated inflammatory pain.
Zhang Y, Song N, Liu F, Lin J, Liu M, Huang C, Liao D, Zhou C, Wang H, Shen J
International journal of oral science 2019 Sep 10;11(3):24
International journal of oral science 2019 Sep 10;11(3):24
Cordycepin (3'-deoxyadenosine) promotes remyelination via suppression of neuroinflammation in a cuprizone-induced mouse model of demyelination.
Jia Y, Li H, Bao H, Zhang D, Feng L, Xiao Y, Zhu K, Hou Y, Luo S, Zhang Y, Xiao L, Chen X, Zhou J, Wang C, Wang G, Yu H, Xiao C, Du J
International immunopharmacology 2019 Oct;75:105777
International immunopharmacology 2019 Oct;75:105777
Glutaminyl cyclase inhibitor exhibits anti-inflammatory effects in both AD and LPS-induced inflammatory model mice.
Wang X, Wang L, Yu X, Li Y, Liu Z, Zou Y, Zheng Y, He Z, Wu H
International immunopharmacology 2019 Oct;75:105770
International immunopharmacology 2019 Oct;75:105770
Antinociceptive effect of isoorientin against neuropathic pain induced by the chronic constriction injury of the sciatic nerve in mice.
Zhang G, Liu N, Zhu C, Ma L, Yang J, Du J, Zhang W, Sun T, Niu J, Yu J
International immunopharmacology 2019 Oct;75:105753
International immunopharmacology 2019 Oct;75:105753
Propentofylline reduces mechanical allodynia and induces mitogen-activated protein kinase phosphatase-1: An experimental study in a rat model of acute incisional pain.
Yang Y, Shi Y, Jia J, Wang S, Chang H, Li M, Jin X, Wang J
Neurological research 2019 Oct;41(10):900-908
Neurological research 2019 Oct;41(10):900-908
Protective effect of 4-Methoxy benzyl alcohol on the neurovascular unit after cerebral ischemia reperfusion injury.
He F, Dai R, Zhou X, Li X, Song X, Yan H, Meng Q, Yang C, Lin Q
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109260
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109260
Nanozyme-Based Bandage with Single-Atom Catalysis for Brain Trauma.
Yan R, Sun S, Yang J, Long W, Wang J, Mu X, Li Q, Hao W, Zhang S, Liu H, Gao Y, Ouyang L, Chen J, Liu S, Zhang XD, Ming D
ACS nano 2019 Oct 22;13(10):11552-11560
ACS nano 2019 Oct 22;13(10):11552-11560
P2Y(14) receptor is functionally expressed in satellite glial cells and mediates interleukin-1β and chemokine CCL2 secretion.
Lin J, Liu F, Zhang YY, Song N, Liu MK, Fang XY, Liao DQ, Zhou C, Wang H, Shen JF
Journal of cellular physiology 2019 Nov;234(11):21199-21210
Journal of cellular physiology 2019 Nov;234(11):21199-21210
Magnolol exhibits anti-inflammatory and neuroprotective effects in a rat model of intracerebral haemorrhage.
Zhou F, Jiang Z, Yang B, Hu Z
Brain, behavior, and immunity 2019 Mar;77:161-167
Brain, behavior, and immunity 2019 Mar;77:161-167
Modulation of α-adrenoceptor signalling protects photoreceptors after retinal detachment by inhibiting oxidative stress and inflammation.
Li T, Yang S, She X, Yan Q, Zhang P, Zhu H, Wang F, Luo X, Sun X
British journal of pharmacology 2019 Mar;176(6):801-813
British journal of pharmacology 2019 Mar;176(6):801-813
Combinatory FK506 and Minocycline Treatment Alleviates Prion-Induced Neurodegenerative Events via Caspase-Mediated MAPK-NRF2 Pathway.
Shah SZA, Zhao D, Taglialatela G, Hussain T, Dong H, Sabir N, Mangi MH, Wu W, Lai M, Zhang X, Duan Y, Wang L, Zhou X, Yang L
International journal of molecular sciences 2019 Mar 6;20(5)
International journal of molecular sciences 2019 Mar 6;20(5)
AKR1B10 (Aldo-keto reductase family 1 B10) promotes brain metastasis of lung cancer cells in a multi-organ microfluidic chip model.
Liu W, Song J, Du X, Zhou Y, Li Y, Li R, Lyu L, He Y, Hao J, Ben J, Wang W, Shi H, Wang Q
Acta biomaterialia 2019 Jun;91:195-208
Acta biomaterialia 2019 Jun;91:195-208
Effects of astrocyte on neuronal outgrowth in a layered 3D structure.
Fang A, Li D, Hao Z, Wang L, Pan B, Gao L, Qu X, He J
Biomedical engineering online 2019 Jun 18;18(1):74
Biomedical engineering online 2019 Jun 18;18(1):74
Toxicity mechanism of sevoflurane in neural stem cells of rats through DNA methylation.
Wang K, Tian Y, Zhang Y, Li X, Wei X, Hu H, Xu S
Experimental and therapeutic medicine 2019 Jul;18(1):237-241
Experimental and therapeutic medicine 2019 Jul;18(1):237-241
GABA(B) receptor activation attenuates inflammatory orofacial pain by modulating interleukin-1β in satellite glial cells: Role of NF-κB and MAPK signaling pathways.
Liu F, Zhang YY, Song N, Lin J, Liu MK, Huang CL, Zhou C, Wang H, Wang M, Shen JF
Brain research bulletin 2019 Jul;149:240-250
Brain research bulletin 2019 Jul;149:240-250
Chondroitin sulfate proteoglycan represses neural stem/progenitor cells migration via PTPσ/α-actinin4 signaling pathway.
Zhong J, Lan C, Zhang C, Yang Y, Chen WX, Zhang KY, Zhao HL, Fang XY, Li HH, Tan L, Wang P, Ge HF, Hu R, Feng H
Journal of cellular biochemistry 2019 Jul;120(7):11008-11021
Journal of cellular biochemistry 2019 Jul;120(7):11008-11021
Chronic mild hypoxia promotes hippocampal neurogenesis involving Notch1 signaling in epileptic rats.
Sun C, Fu J, Qu Z, Li D, Si P, Qiao Q, Zhang W, Xue Y, Zhen J, Wang W
Brain research 2019 Jul 1;1714:88-98
Brain research 2019 Jul 1;1714:88-98
The DosR antigen Rv1737c from Mycobacterium tuberculosis confers inflammation regulation in tuberculosis infection.
Gao X, Wu C, Wang X, Xu H, Wu Y, Li Y, Jia Y, Wei C, He W, Wang Y, Zhang B
Scandinavian journal of immunology 2019 Jan;89(1):e12729
Scandinavian journal of immunology 2019 Jan;89(1):e12729
PRRT2 deficiency induces paroxysmal kinesigenic dyskinesia by influencing synaptic function in the primary motor cortex of rats.
Mo J, Wang B, Zhu X, Wu X, Liu Y
Neurobiology of disease 2019 Jan;121:274-285
Neurobiology of disease 2019 Jan;121:274-285
HMGB1-mediated differential response on hippocampal neurotransmitter disorder and neuroinflammation in adolescent male and female mice following cold exposure.
Xu B, Zang SC, Li SZ, Guo JR, Wang JF, Wang D, Zhang LP, Yang HM, Lian S
Brain, behavior, and immunity 2019 Feb;76:223-235
Brain, behavior, and immunity 2019 Feb;76:223-235
Redox Trimetallic Nanozyme with Neutral Environment Preference for Brain Injury.
Mu X, Wang J, Li Y, Xu F, Long W, Ouyang L, Liu H, Jing Y, Wang J, Dai H, Liu Q, Sun Y, Liu C, Zhang XD
ACS nano 2019 Feb 26;13(2):1870-1884
ACS nano 2019 Feb 26;13(2):1870-1884
Microglia as modulators of exosomal alpha-synuclein transmission.
Xia Y, Zhang G, Han C, Ma K, Guo X, Wan F, Kou L, Yin S, Liu L, Huang J, Xiong N, Wang T
Cell death & disease 2019 Feb 20;10(3):174
Cell death & disease 2019 Feb 20;10(3):174
Overriding FUS autoregulation in mice triggers gain-of-toxic dysfunctions in RNA metabolism and autophagy-lysosome axis.
Ling SC, Dastidar SG, Tokunaga S, Ho WY, Lim K, Ilieva H, Parone PA, Tyan SH, Tse TM, Chang JC, Platoshyn O, Bui NB, Bui A, Vetto A, Sun S, McAlonis-Downes M, Han JS, Swing D, Kapeli K, Yeo GW, Tessarollo L, Marsala M, Shaw CE, Tucker-Kellogg G, La Spada AR, Lagier-Tourenne C, Da Cruz S, Cleveland DW
eLife 2019 Feb 12;8
eLife 2019 Feb 12;8
Pseudovirus rVSVΔG-ZEBOV-GP Infects Neurons in Retina and CNS, Causing Apoptosis and Neurodegeneration in Neonatal Mice.
McWilliams IL, Kielczewski JL, Ireland DDC, Sykes JS, Lewkowicz AP, Konduru K, Xu BC, Chan CC, Caspi RR, Manangeeswaran M, Verthelyi D
Cell reports 2019 Feb 12;26(7):1718-1726.e4
Cell reports 2019 Feb 12;26(7):1718-1726.e4
Possible mechanisms of prenatal cold stress induced-anxiety-like behavior depression in offspring rats.
Lian S, Xu B, Wang D, Wang L, Li W, Yao R, Ji H, Wang J, Guo J, Li S, Yang H
Behavioural brain research 2019 Feb 1;359:304-311
Behavioural brain research 2019 Feb 1;359:304-311
Melatonin receptor activation provides cerebral protection after traumatic brain injury by mitigating oxidative stress and inflammation via the Nrf2 signaling pathway.
Wang J, Jiang C, Zhang K, Lan X, Chen X, Zang W, Wang Z, Guan F, Zhu C, Yang X, Lu H, Wang J
Free radical biology & medicine 2019 Feb 1;131:345-355
Free radical biology & medicine 2019 Feb 1;131:345-355
Resveratrol suppresses the myofibroblastic phenotype and fibrosis formation in kidneys via proliferation-related signalling pathways.
Zhang X, Lu H, Xie S, Wu C, Guo Y, Xiao Y, Zheng S, Zhu H, Zhang Y, Bai Y
British journal of pharmacology 2019 Dec;176(24):4745-4759
British journal of pharmacology 2019 Dec;176(24):4745-4759
The P2Y(14) receptor in the trigeminal ganglion contributes to the maintenance of inflammatory pain.
Lin J, Zhang YY, Liu F, Fang XY, Liu MK, Huang CL, Wang H, Liao DQ, Zhou C, Shen JF
Neurochemistry international 2019 Dec;131:104567
Neurochemistry international 2019 Dec;131:104567
The glutamatergic system and astrocytic impairment in rat hippocampus: a comparative study of underlying etiology and pathophysiology of depression.
Jiang S, Zhang QA, Guo Q, Di Z
Journal of integrative neuroscience 2019 Dec 30;18(4):387-392
Journal of integrative neuroscience 2019 Dec 30;18(4):387-392
Silencing of microRNA-146a alleviates the neural damage in temporal lobe epilepsy by down-regulating Notch-1.
Huang H, Cui G, Tang H, Kong L, Wang X, Cui C, Xiao Q, Ji H
Molecular brain 2019 Dec 3;12(1):102
Molecular brain 2019 Dec 3;12(1):102
Folic Acid Decreases Astrocyte Apoptosis by Preventing Oxidative Stress-Induced Telomere Attrition.
Li W, Ma Y, Li Z, Lv X, Wang X, Zhou D, Luo S, Wilson JX, Huang G
International journal of molecular sciences 2019 Dec 20;21(1)
International journal of molecular sciences 2019 Dec 20;21(1)
I-8, a novel inhibitor of mutant IDH1, inhibits cancer progression in vitro and in vivo.
Jia P, Wu Y, Du H, Yang L, Zhang Z, Ma T, Li S, Yuan S, Lu L, Zha X
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2019 Dec 1;140:105072
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2019 Dec 1;140:105072
GA-binding protein GABPβ1 is required for the proliferation of neural stem/progenitor cells.
Liu C, Dai SK, Sun Z, Wang Z, Liu PP, Du HZ, Yu S, Liu CM, Teng ZQ
Stem cell research 2019 Aug;39:101501
Stem cell research 2019 Aug;39:101501
Astroglial dysfunctions drive aberrant synaptogenesis and social behavioral deficits in mice with neonatal exposure to lengthy general anesthesia.
Zhou B, Chen L, Liao P, Huang L, Chen Z, Liao D, Yang L, Wang J, Yu G, Wang L, Zhang J, Zuo Y, Liu J, Jiang R
PLoS biology 2019 Aug;17(8):e3000086
PLoS biology 2019 Aug;17(8):e3000086
Neuroprotective effects of an engineered commensal bacterium in the 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine Parkinson disease mouse model via producing glucagon-like peptide-1.
Fang X, Tian P, Zhao X, Jiang C, Chen T
Journal of neurochemistry 2019 Aug;150(4):441-452
Journal of neurochemistry 2019 Aug;150(4):441-452
Microglia Activated by Excess Cortisol Induce HMGB1 Acetylation and Neuroinflammation in the Hippocampal DG Region of Mice Following Cold Exposure.
Xu B, Lang LM, Li SZ, Guo JR, Wang JF, Yang HM, Lian S
Biomolecules 2019 Aug 30;9(9)
Biomolecules 2019 Aug 30;9(9)
miR-504 suppresses mesenchymal phenotype of glioblastoma by directly targeting the FZD7-mediated Wnt-β-catenin pathway.
Liu Q, Guan Y, Li Z, Wang Y, Liu Y, Cui R, Wang Y
Journal of experimental & clinical cancer research : CR 2019 Aug 16;38(1):358
Journal of experimental & clinical cancer research : CR 2019 Aug 16;38(1):358
Icariin attenuates neuroinflammation and exerts dopamine neuroprotection via an Nrf2-dependent manner.
Zhang B, Wang G, He J, Yang Q, Li D, Li J, Zhang F
Journal of neuroinflammation 2019 Apr 22;16(1):92
Journal of neuroinflammation 2019 Apr 22;16(1):92
Ginkgo biloba Extract Inhibits Astrocytic Lipocalin-2 Expression and Alleviates Neuroinflammatory Injury via the JAK2/STAT3 Pathway After Ischemic Brain Stroke.
Zhang Y, Liu J, Yang B, Zheng Y, Yao M, Sun M, Xu L, Lin C, Chang D, Tian F
Frontiers in pharmacology 2018;9:518
Frontiers in pharmacology 2018;9:518
Yi-nao-jie-yu Prescription Exerts a Positive Effect on Neurogenesis by Regulating Notch Signals in the Hippocampus of Post-stroke Depression Rats.
Tian H, Li X, Tang Q, Zhang W, Li Q, Sun X, Zhao R, Ma C, Liu H, Gao Y, Han F
Frontiers in psychiatry 2018;9:483
Frontiers in psychiatry 2018;9:483
Neuroprotective Effects of Ginsenoside-Rg1 Against Depression-Like Behaviors via Suppressing Glial Activation, Synaptic Deficits, and Neuronal Apoptosis in Rats.
Fan C, Song Q, Wang P, Li Y, Yang M, Yu SY
Frontiers in immunology 2018;9:2889
Frontiers in immunology 2018;9:2889
Skull optical clearing window for in vivo imaging of the mouse cortex at synaptic resolution.
Zhao YJ, Yu TT, Zhang C, Li Z, Luo QM, Xu TH, Zhu D
Light, science & applications 2018;7:17153
Light, science & applications 2018;7:17153
Glia Maturation Factor and Mast Cell-Dependent Expression of Inflammatory Mediators and Proteinase Activated Receptor-2 in Neuroinflammation.
Kempuraj D, Selvakumar GP, Thangavel R, Ahmed ME, Zaheer S, Kumar KK, Yelam A, Kaur H, Dubova I, Raikwar SP, Iyer SS, Zaheer A
Journal of Alzheimer's disease : JAD 2018;66(3):1117-1129
Journal of Alzheimer's disease : JAD 2018;66(3):1117-1129
Neuroprotective Effects of Curcumin on IL-1β-Induced Neuronal Apoptosis and Depression-Like Behaviors Caused by Chronic Stress in Rats.
Fan C, Song Q, Wang P, Li Y, Yang M, Yu SY
Frontiers in cellular neuroscience 2018;12:516
Frontiers in cellular neuroscience 2018;12:516
Honokiol Ameliorates Amyloidosis and Neuroinflammation and Improves Cognitive Impairment in Alzheimer's Disease Transgenic Mice.
Wang D, Dong X, Wang C
The Journal of pharmacology and experimental therapeutics 2018 Sep;366(3):470-478
The Journal of pharmacology and experimental therapeutics 2018 Sep;366(3):470-478
Curcumin attenuates chronic intermittent hypoxia-induced brain injuries by inhibiting AQP4 and p38 MAPK pathway.
Wang B, Li W, Jin H, Nie X, Shen H, Li E, Wang W
Respiratory physiology & neurobiology 2018 Sep;255:50-57
Respiratory physiology & neurobiology 2018 Sep;255:50-57
GABAB receptor mediate hippocampal neuroinflammation in adolescent male and female mice after cold expose.
Xu B, Lian S, Li SZ, Guo JR, Wang JF, Wang D, Zhang LP, Yang HM
Brain research bulletin 2018 Sep;142:163-175
Brain research bulletin 2018 Sep;142:163-175
Bexarotene protects against neurotoxicity partially through a PPARγ-dependent mechanism in mice following traumatic brain injury.
He J, Liu H, Zhong J, Guo Z, Wu J, Zhang H, Huang Z, Jiang L, Li H, Zhang Z, Liu L, Wu Y, Qi L, Sun X, Cheng C
Neurobiology of disease 2018 Sep;117:114-124
Neurobiology of disease 2018 Sep;117:114-124
Decreased expression of LATS1 correlates with astrogliosis after spinal cord injury.
Wang Y, Chen M
Biochemical and biophysical research communications 2018 Oct 20;505(1):151-156
Biochemical and biophysical research communications 2018 Oct 20;505(1):151-156
Deficiency in augmenter of liver regeneration accelerates liver fibrosis by promoting migration of hepatic stellate cell.
Ai WL, Dong LY, Wang J, Li ZW, Wang X, Gao J, Wu Y, An W
Biochimica et biophysica acta. Molecular basis of disease 2018 Nov;1864(11):3780-3791
Biochimica et biophysica acta. Molecular basis of disease 2018 Nov;1864(11):3780-3791
Beneficial Effects of Exercise Pretreatment in a Sporadic Alzheimer's Rat Model.
Wu C, Yang L, Tucker D, Dong Y, Zhu L, Duan R, Liu TC, Zhang Q
Medicine and science in sports and exercise 2018 May;50(5):945-956
Medicine and science in sports and exercise 2018 May;50(5):945-956
N-methyl D-aspartate receptor subtype 2B antagonist, Ro 25-6981, attenuates neuropathic pain by inhibiting postsynaptic density 95 expression.
Huang LE, Guo SH, Thitiseranee L, Yang Y, Zhou YF, Yao YX
Scientific reports 2018 May 18;8(1):7848
Scientific reports 2018 May 18;8(1):7848
A model to study complement involvement in experimental retinal degeneration.
Mohlin C, Sandholm K, Kvanta A, Ekdahl KN, Johansson K
Upsala journal of medical sciences 2018 Mar;123(1):28-42
Upsala journal of medical sciences 2018 Mar;123(1):28-42
Early Postnatal Exposure to Airborne Fine Particulate Matter Induces Autism-like Phenotypes in Male Rats.
Li K, Li L, Cui B, Gai Z, Li Q, Wang S, Yan J, Lin B, Tian L, Liu H, Liu X, Xi Z
Toxicological sciences : an official journal of the Society of Toxicology 2018 Mar 1;162(1):189-199
Toxicological sciences : an official journal of the Society of Toxicology 2018 Mar 1;162(1):189-199
Knockdown of Ski decreased the reactive astrocytes proliferation in vitro induced by oxygen-glucose deprivation/reoxygenation.
Zhao X, Zhou KS, Li ZH, Nan W, Wang J, Xia YY, Zhang HH
Journal of cellular biochemistry 2018 Jun;119(6):4548-4558
Journal of cellular biochemistry 2018 Jun;119(6):4548-4558
Transplantation of hypoxic preconditioned neural stem cells benefits functional recovery via enhancing neurotrophic secretion after spinal cord injury in rats.
Fan WL, Liu P, Wang G, Pu JG, Xue X, Zhao JH
Journal of cellular biochemistry 2018 Jun;119(6):4339-4351
Journal of cellular biochemistry 2018 Jun;119(6):4339-4351
Tert-butylhydroquinone post-treatment attenuates neonatal hypoxic-ischemic brain damage in rats.
Zhang J, Tucker LD, DongYan, Lu Y, Yang L, Wu C, Li Y, Zhang Q
Neurochemistry international 2018 Jun;116:1-12
Neurochemistry international 2018 Jun;116:1-12
Glia maturation factor beta is required for reactive gliosis after traumatic brain injury in zebrafish.
Yin G, Du M, Li R, Li K, Huang X, Duan D, Ai X, Yao F, Zhang L, Hu Z, Wu B
Experimental neurology 2018 Jul;305:129-138
Experimental neurology 2018 Jul;305:129-138
ZDHHC8 critically regulates seizure susceptibility in epilepsy.
Yang Q, Zheng F, Hu Y, Yang Y, Li Y, Chen G, Wang W, He M, Zhou R, Ma Y, Xu D, Tian X, Gao X, Wang Q, Wang X
Cell death & disease 2018 Jul 23;9(8):795
Cell death & disease 2018 Jul 23;9(8):795
Tick-Borne Encephalitis Virus Nonstructural Protein NS5 Induces RANTES Expression Dependent on the RNA-Dependent RNA Polymerase Activity.
Zheng Z, Yang J, Jiang X, Liu Y, Zhang X, Li M, Zhang M, Fu M, Hu K, Wang H, Luo MH, Gong P, Hu Q
Journal of immunology (Baltimore, Md. : 1950) 2018 Jul 1;201(1):53-68
Journal of immunology (Baltimore, Md. : 1950) 2018 Jul 1;201(1):53-68
Photobiomodulation therapy promotes neurogenesis by improving post-stroke local microenvironment and stimulating neuroprogenitor cells.
Yang L, Tucker D, Dong Y, Wu C, Lu Y, Li Y, Zhang J, Liu TC, Zhang Q
Experimental neurology 2018 Jan;299(Pt A):86-96
Experimental neurology 2018 Jan;299(Pt A):86-96
Long-term treadmill exercise attenuates Aβ burdens and astrocyte activation in APP/PS1 mouse model of Alzheimer's disease.
Zhang J, Guo Y, Wang Y, Song L, Zhang R, Du Y
Neuroscience letters 2018 Feb 14;666:70-77
Neuroscience letters 2018 Feb 14;666:70-77
Neuroprotective Effect of Anethole Against Neuropathic Pain Induced by Chronic Constriction Injury of the Sciatic Nerve in Mice.
Wang B, Zhang G, Yang M, Liu N, Li YX, Ma H, Ma L, Sun T, Tan H, Yu J
Neurochemical research 2018 Dec;43(12):2404-2422
Neurochemical research 2018 Dec;43(12):2404-2422
Dietary eicosapentaenoic acid normalizes hippocampal omega-3 and 6 polyunsaturated fatty acid profile, attenuates glial activation and regulates BDNF function in a rodent model of neuroinflammation induced by central interleukin-1β administration.
Dong Y, Xu M, Kalueff AV, Song C
European journal of nutrition 2018 Aug;57(5):1781-1791
European journal of nutrition 2018 Aug;57(5):1781-1791
Reversal of pancreatic desmoplasia by re-educating stellate cells with a tumour microenvironment-activated nanosystem.
Han X, Li Y, Xu Y, Zhao X, Zhang Y, Yang X, Wang Y, Zhao R, Anderson GJ, Zhao Y, Nie G
Nature communications 2018 Aug 23;9(1):3390
Nature communications 2018 Aug 23;9(1):3390
Effect of tumor necrosis factor-α on the expression of the ammonia transporter Rhcg in the brain in mice with acute liver failure.
Wang W, Lu H, Lu X, Wang D, Wang Z, Dai W, Wang J, Liu P
Journal of neuroinflammation 2018 Aug 22;15(1):234
Journal of neuroinflammation 2018 Aug 22;15(1):234
Expressions of nestin and glial fibrillary acidic protein in rat retina after optic nerve transection.
Wang L, Li P
International journal of ophthalmology 2017;10(10):1510-1515
International journal of ophthalmology 2017;10(10):1510-1515
Intranasal Delivery of a Caspase-1 Inhibitor in the Treatment of Global Cerebral Ischemia.
Zhao N, Zhuo X, Lu Y, Dong Y, Ahmed ME, Tucker D, Scott EL, Zhang Q
Molecular neurobiology 2017 Sep;54(7):4936-4952
Molecular neurobiology 2017 Sep;54(7):4936-4952
An Increase of Sigma-1 Receptor in the Penumbra Neuron after Acute Ischemic Stroke.
Zhang X, Wu F, Jiao Y, Tang T, Yang L, Lu C, Zhang Y, Zhang Y, Bai Y, Chao J, Teng G, Yao H
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2017 Sep;26(9):1981-1987
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2017 Sep;26(9):1981-1987
Neuroprotective Effect of Chitosan Oligosaccharide on Hypoxic-Ischemic Brain Damage in Neonatal Rats.
Wu W, Wei W, Lu M, Zhu X, Liu N, Niu Y, Sun T, Li Y, Yu J
Neurochemical research 2017 Nov;42(11):3186-3198
Neurochemical research 2017 Nov;42(11):3186-3198
Discovery of Aquaporin-1 and Aquaporin-4 Expression in an Intramedullary Spinal Cord Ependymal Cyst: Case Report.
Shepard MJ, Padmanaban V, Edwards NA, Chittiboina P, Ray-Chaudhury A, Heiss JD
World neurosurgery 2017 Nov;107:1046.e1-1046.e7
World neurosurgery 2017 Nov;107:1046.e1-1046.e7
Chronic metformin treatment facilitates seizure termination.
Yang Y, Zhu B, Zheng F, Li Y, Zhang Y, Hu Y, Wang X
Biochemical and biophysical research communications 2017 Mar 4;484(2):450-455
Biochemical and biophysical research communications 2017 Mar 4;484(2):450-455
Inhibition of Blood-Brain Barrier Disruption by an Apolipoprotein E-Mimetic Peptide Ameliorates Early Brain Injury in Experimental Subarachnoid Hemorrhage.
Pang J, Chen Y, Kuai L, Yang P, Peng J, Wu Y, Chen Y, Vitek MP, Chen L, Sun X, Jiang Y
Translational stroke research 2017 Jun;8(3):257-272
Translational stroke research 2017 Jun;8(3):257-272
Human Umbilical Cord Mesenchymal Stem Cells Overexpressing Nerve Growth Factor Ameliorate Diabetic Cystopathy in Rats.
WenBo W, Fei Z, YiHeng D, Wei W, TingMang Y, WenHao Z, QianRu L, HaiTao L
Neurochemical research 2017 Dec;42(12):3537-3547
Neurochemical research 2017 Dec;42(12):3537-3547
The role of sodium hydrosulfide in attenuating the aging process via PI3K/AKT and CaMKKβ/AMPK pathways.
Chen X, Zhao X, Cai H, Sun H, Hu Y, Huang X, Kong W, Kong W
Redox biology 2017 Aug;12:987-1003
Redox biology 2017 Aug;12:987-1003
Early Minocycline and Late FK506 Treatment Improves Survival and Alleviates Neuroinflammation, Neurodegeneration, and Behavioral Deficits in Prion-Infected Hamsters.
Shah SZA, Zhao D, Taglialatela G, Khan SH, Hussain T, Dong H, Lai M, Zhou X, Yang L
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2017 Apr;14(2):463-483
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2017 Apr;14(2):463-483
Expression of Signaling Molecules in Progressive Multifocal Leukoencephalopathy.
Wollebo HS, Cotto B, Adiga R, Langford D, White MK
Current HIV research 2016;14(1):47-53
Current HIV research 2016;14(1):47-53
Effects of oxidative stress on hyperglycaemia-induced brain malformations in a diabetes mouse model.
Jin Y, Wang G, Han SS, He MY, Cheng X, Ma ZL, Wu X, Yang X, Liu GS
Experimental cell research 2016 Sep 10;347(1):201-211
Experimental cell research 2016 Sep 10;347(1):201-211
Oligodendroglial deletion of ESCRT-I component TSG101 causes spongiform encephalopathy.
Walker WP, Oehler A, Edinger AL, Wagner KU, Gunn TM
Biology of the cell 2016 Nov;108(11):324-337
Biology of the cell 2016 Nov;108(11):324-337
Poly-L-ornithine enhances migration of neural stem/progenitor cells via promoting α-Actinin 4 binding to actin filaments.
Ge H, Yu A, Chen J, Yuan J, Yin Y, Duanmu W, Tan L, Yang Y, Lan C, Chen W, Feng H, Hu R
Scientific reports 2016 Nov 22;6:37681
Scientific reports 2016 Nov 22;6:37681
Formylpeptide Receptors Promote the Migration and Differentiation of Rat Neural Stem Cells.
Wang G, Zhang L, Chen X, Xue X, Guo Q, Liu M, Zhao J
Scientific reports 2016 May 13;6:25946
Scientific reports 2016 May 13;6:25946
Intrathecal Injection of Human Umbilical Cord-Derived Mesenchymal Stem Cells Ameliorates Neuropathic Pain in Rats.
Chen C, Chen F, Yao C, Shu S, Feng J, Hu X, Hai Q, Yao S, Chen X
Neurochemical research 2016 Dec;41(12):3250-3260
Neurochemical research 2016 Dec;41(12):3250-3260
Potential implications of Apolipoprotein E in early brain injury after experimental subarachnoid hemorrhage: Involvement in the modulation of blood-brain barrier integrity.
Pang J, Wu Y, Peng J, Yang P, Kuai L, Qin X, Cao F, Sun X, Chen L, Vitek MP, Jiang Y
Oncotarget 2016 Aug 30;7(35):56030-56044
Oncotarget 2016 Aug 30;7(35):56030-56044
Endoplasmic reticulum stress mediates JNK-dependent IRS-1 serine phosphorylation and results in Tau hyperphosphorylation in amyloid β oligomer-treated PC12 cells and primary neurons.
Zhang X, Tang S, Zhang Q, Shao W, Han X, Wang Y, Du Y
Gene 2016 Aug 10;587(2):183-93
Gene 2016 Aug 10;587(2):183-93
Neural stem/progenitor cells react to non-glial cns neoplasms.
Campbell JG, Miller DC, Cundiff DD, Feng Q, Litofsky NS
SpringerPlus 2015;4:53
SpringerPlus 2015;4:53
The Neuropilin-1 Inhibitor, ATWLPPR Peptide, Prevents Experimental Diabetes-Induced Retinal Injury by Preserving Vascular Integrity and Decreasing Oxidative Stress.
Wang J, Wang S, Li M, Wu D, Liu F, Yang R, Ji S, Ji A, Li Y
PloS one 2015;10(11):e0142571
PloS one 2015;10(11):e0142571
Deficiency of macrophage migration inhibitory factor attenuates tau hyperphosphorylation in mouse models of Alzheimer's disease.
Li SQ, Yu Y, Han JZ, Wang D, Liu J, Qian F, Fan GH, Bucala R, Ye RD
Journal of neuroinflammation 2015 Sep 17;12:177
Journal of neuroinflammation 2015 Sep 17;12:177
Poly-L-ornithine promotes preferred differentiation of neural stem/progenitor cells via ERK signalling pathway.
Ge H, Tan L, Wu P, Yin Y, Liu X, Meng H, Cui G, Wu N, Lin J, Hu R, Feng H
Scientific reports 2015 Oct 27;5:15535
Scientific reports 2015 Oct 27;5:15535
Disrupted SOX10 function causes spongiform neurodegeneration in gray tremor mice.
Anderson SR, Lee I, Ebeling C, Stephenson DA, Schweitzer KM, Baxter D, Moon TM, LaPierre S, Jaques B, Silvius D, Wegner M, Hood LE, Carlson G, Gunn TM
Mammalian genome : official journal of the International Mammalian Genome Society 2015 Feb;26(1-2):80-93
Mammalian genome : official journal of the International Mammalian Genome Society 2015 Feb;26(1-2):80-93
An immortalized rat pancreatic stellate cell line RP-2 as a new cell model for evaluating pancreatic fibrosis, inflammation and immunity.
Piao RL, Xiu M, Brigstock DR, Gao RP
Hepatobiliary & pancreatic diseases international : HBPD INT 2015 Dec;14(6):651-9
Hepatobiliary & pancreatic diseases international : HBPD INT 2015 Dec;14(6):651-9
Severely exacerbated neuromyelitis optica rat model with extensive astrocytopathy by high affinity anti-aquaporin-4 monoclonal antibody.
Kurosawa K, Misu T, Takai Y, Sato DK, Takahashi T, Abe Y, Iwanari H, Ogawa R, Nakashima I, Fujihara K, Hamakubo T, Yasui M, Aoki M
Acta neuropathologica communications 2015 Dec 4;3:82
Acta neuropathologica communications 2015 Dec 4;3:82
Limb remote ischemic postconditioning protects cerebral ischemia from injury associated with expression of HIF-1α in rats.
Zong Y, Jiang L, Zhang M, Zhou F, Qi W, Li S, Yang H, Zou Y, Xia Q, Zhou X, Hu X, Wang T
BMC neuroscience 2015 Dec 29;16:97
BMC neuroscience 2015 Dec 29;16:97
Remote ischemic post-conditioning improves neurological function by AQP4 down-regulation in astrocytes.
Li S, Hu X, Zhang M, Zhou F, Lin N, Xia Q, Zhou Y, Qi W, Zong Y, Yang H, Wang T
Behavioural brain research 2015 Aug 1;289:1-8
Behavioural brain research 2015 Aug 1;289:1-8
The positive effects of Ginsenoside Rg1 upon the hematopoietic microenvironment in a D-Galactose-induced aged rat model.
Hu W, Jing P, Wang L, Zhang Y, Yong J, Wang Y
BMC complementary and alternative medicine 2015 Apr 15;15:119
BMC complementary and alternative medicine 2015 Apr 15;15:119
Ginsenoside Rg1 prevents cognitive impairment and hippocampus senescence in a rat model of D-galactose-induced aging.
Zhu J, Mu X, Zeng J, Xu C, Liu J, Zhang M, Li C, Chen J, Li T, Wang Y
PloS one 2014;9(6):e101291
PloS one 2014;9(6):e101291
Photoreceptor degeneration, structural remodeling and glial activation: a morphological study on a genetic mouse model for pericyte deficiency.
Genové G, Mollick T, Johansson K
Neuroscience 2014 Oct 24;279:269-84
Neuroscience 2014 Oct 24;279:269-84
Increased expression of Notch1 in temporal lobe epilepsy: animal models and clinical evidence.
Liu X, Yang Z, Yin Y, Deng X
Neural regeneration research 2014 Mar 1;9(5):526-33
Neural regeneration research 2014 Mar 1;9(5):526-33
Puerarin protected the brain from cerebral ischemia injury via astrocyte apoptosis inhibition.
Wang N, Zhang Y, Wu L, Wang Y, Cao Y, He L, Li X, Zhao J
Neuropharmacology 2014 Apr;79:282-9
Neuropharmacology 2014 Apr;79:282-9
Effects of phlorizin on diabetic retinopathy according to isobaric tags for relative and absolute quantification-based proteomics in db/db mice.
Zhang SY, Li BY, Li XL, Cheng M, Cai Q, Yu F, Wang WD, Tan M, Yan G, Hu SL, Gao HQ
Molecular vision 2013;19:812-21
Molecular vision 2013;19:812-21
Contribution of SATB2 to the stronger osteogenic potential of bone marrow stromal cells from craniofacial bones.
Zhang P, Men J, Fu Y, Shan T, Ye J, Wu Y, Tao Z, Liu L, Jiang H
Cell and tissue research 2012 Dec;350(3):425-37
Cell and tissue research 2012 Dec;350(3):425-37
Further assessment of neuropathology in retinal explants and neuroprotection by human neural progenitor cells.
Mohlin C, Liljekvist-Soltic I, Johansson K
Journal of neural engineering 2011 Dec;8(6):066012
Journal of neural engineering 2011 Dec;8(6):066012
Progranulin is expressed within motor neurons and promotes neuronal cell survival.
Ryan CL, Baranowski DC, Chitramuthu BP, Malik S, Li Z, Cao M, Minotti S, Durham HD, Kay DG, Shaw CA, Bennett HP, Bateman A
BMC neuroscience 2009 Oct 27;10:130
BMC neuroscience 2009 Oct 27;10:130
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- C6 cells were subjected to SDS PAGE followed by western blot with 16825-1-AP(GFAP antibody) at dilution of 1:800
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human brain using 16825-1-AP(GFAP antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The GFAP antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human GFAP. This antibody recognizes human,mouse,rat antigen. The GFAP antibody has been validated for the following applications: ELISA, IHC, WB analysis.
