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- Antibody Data
- Antigen structure
- References [289]
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- Product number
- 60190-1-Ig - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#60190-1-Ig, RRID:AB_10838694
- Product name
- GFAP antibody
- Antibody type
- Monoclonal
- Description
- GFAP antibody (Cat. #60190-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, mouse, rat, pig, rabbit and has been validated for the following applications: IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat, Porcine, Rabbit
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 4B2E10
- Vial size
- 20ul, 150ul
Submitted references Oxymatrine alleviates symptoms in high-fat diet and STZ-induced SD rats with painful diabetic neuropathy by reducing inflammation and oxidative stress.
Integrating network pharmacology and transcriptomics to reveal the therapeutic effect of Long Mu Ning Xin Decoction on attention-deficit/hyperactivity disorder by regulating cAMP and PI3K/AKT pathways.
Microvascular endothelial metabolic dysfunction drives cerebral edema through bioenergetic failure after ischemia-reperfusion.
PTBP1-mediated inhibition of circular RNA SCMH1 biogenesis impairs brain recovery after ischemic stroke.
P2X7 receptor-mediated cGAS-STING pathway activation underlies chronic stress-induced depressive-like behaviors.
Reduced nuclear TDP-43 and cytoplasmic DLK1 as markers of motor neuron degeneration in amyotrophic lateral sclerosis.
Modulating GRP75 to restore calcium homeostasis: a novel neuroprotective strategy of CRSE6(#) in Parkinson's disease models.
Investigating the Effect and Mechanism of Protocatechuic Aldehyde on Vascular Dementia Based on Multi-Omics Approach.
Glibenclamide Attenuates Brain Edema After Intracerebral Hemorrhage Through Preservation of Blood-Brain Barrier Integrity and Glymphatic Function.
The engineered probiotic strain Lactococcus lactis MG1363-pMG36e-GLP-1 regulates microglial polarization and gut dysbiosis in a transgenic mouse model of Parkinson's disease.
Phosphodiesterase 4 regulates pyroptosis in subarachnoid hemorrhage.
Astrocyte-Specific Nrf2 Expression Transforms Neurotoxic Reactive Astrocytes to Neuroprotective Phenotype in 3xTg-AD Mice.
Early astrocyte-targeted intervention guided by (18)F-SMBT-1 imaging attenuates disease progression in 3xTg-AD mice.
Decorin Attenuates Epileptogenesis and Modulates Hippocampal Synaptic Plasticity via the mTOR Signalling Pathway.
Astrocytic LCN2 drives neuronal dysfunction in epilepsy by suppressing tunnel nanotube-mediated mitochondrial transfer via NLRP3 inflammasome activation.
The promoting roles of GLP1R and GIPR in stemness maintenance and multiple lineage-specific differentiation of PDLSCs.
Fibrotic scar formation after cerebral ischemic stroke: Targeting the Sonic hedgehog signaling pathway for scar reduction.
Integrated multi-omics analysis identifies potential therapeutic targets for Alzheimer's disease.
Intermittent theta-burst stimulation promotes neurovascular unit remodeling after ischemic stroke in a mouse model.
Shh-S100A10 axis curbs neuronal PANoptosis after ischemic stroke.
YAP Regulates Microglial Anti-Inflammatory Responses and Alleviates Cognitive Impairment Through the IL-33/ST2 Pathway after Traumatic Brain Injury.
Neuro-bone-skin tri-regeneration via a microenvironment-responsive PRP-loaded chitosan hydrogel for traumatic brain injury therapy.
Modulation of glutamate metabolic reprogramming via Ras-Raf-MEK/ERK signaling alleviates immune inflammation of astrocytes in glaucomatous neurodegeneration.
Identification of Fibrinogen C Domain-Containing protein 1 (FIBCD1) as a novel target for treatment of Post-Traumatic stress disorder (PTSD) and discovery of a novel FIBCD1 inhibitor.
Engineered Alzheimer Organoids Validate the Link Between Intracellular and Soluble p-Tau Biomarkers and Highlight the Contribution of Astrocytic Tau.
Injectable Brain Extracellular Matrix Hydrogels Enhance Neuronal Migration and Functional Recovery After Intracerebral Hemorrhage.
The Histone Deacetylase Activator ITSA-1 Improves the Prognosis of Cardiac Arrest Rats by Alleviating Systemic Inflammatory Responses Following Cardiopulmonary Resuscitation.
TRIM14 Inhibition Suppresses Microglial Polarization and Pyroptosis Through the NF-κB/NLRP3 Pathway to Enhance Spinal Cord Injury Repair.
Baicalein improves motor dysfunction and cognitive impairment while promoting remyelination in an animal model of multiple sclerosis through the antioxidant mechanism.
Injectable ion-coordinated double-network conductive hydrogel for spinal cord injury repair.
Promoting spinal cord injury repair by using ZnO@MOFs nanozymes functionalized hydrogel through the ROS microenvironment regulating pathway.
Lactobacillus acidophilus promotes cognitive function recovery via regulating microglial peroxisomal function in cerebral ischemia.
Transcription factor RUNX2 participates in astrocyte-mediated neuropathic pain via transcriptional activation of Ccl2.
PGC-1α Expands Neural Precursor Pool and Facilitates Cognitive Recovery Within AD Hippocampus Through the Regulation of Mitochondrial Dynamics.
Deletion of ZNRF2 Exacerbates MPTP-Induced Parkinson's Disease by Activating mTOR-Mediated Neuroinflammatory Pathways.
USP47 Regulates Excitatory Synaptic Plasticity and Modulates Seizures in Murine Models by Blocking Ubiquitinated AMPAR Degradation.
ILF3 downregulation by circMETTL9: Effect on traumatic brain injury-induced neuroinflammation.
Ptbp1 knockdown induces conversion of rat spinal cord astrocytes into neuron like cells.
Intraventricular Creatine Treatment Attenuates Alzheimer's Disease-Related Neuropathological Changes and Memory Impairment via Inhibiting STAT1 Phosphorylation.
DP1 Receptor Blockade Attenuates Microglial Senescence and Cognitive Decline Caused by PTGDS in Exosomes From Aged Brains.
SPP1 expression after spinal cord compression injury and its effects on glial cell activation.
Chronic ethanol exposure induces hippocampal neuroinflammation and neuronal damage via the astrocytic RUNX1/TOLLIP/TLR3 pathway.
Parylation dependent nuclear export of HMGB1 via exportin 1 contributes to morphine tolerance.
Microglial activation drives neuronal dysregulation in alcohol-induced seizure susceptibility.
Parthenolide Exerts Protection against Hypoxic-Ischemic Brain Damage in Neonatal Rats by Inhibiting Perk-Mediated Endoplasmic Reticulum Stress.
Isoliquiritigenin ameliorates Parkinson's disease via gut microbiota remodeling: potential mediating role of Parabacteroides distasonis.
Neutralizing XCL1 Attenuates Brain Injury and Reduces Lymphocyte and Dendritic Cell Recruitment Following Intracerebral Hemorrhage in Mice.
Trigeminal root demyelination is sufficient to induce trigeminal neuralgia-like facial pain in adult rodents.
MOF-Engineered Platelet-Mimicking Nanocarrier-Encapsulated Cascade Enzymes for ROS Scavenging and Anti-Inflammation in Cerebral Ischemia-Reperfusion Injury.
GRP78 alleviates secondary brain injury by regulating phenotype polarization in astrocytes via JAK2-STAT3 pathway after intracerebral hemorrhage.
Nose-to-Brain Delivery of Circular RNA SCMH1-Loaded Lipid Nanoparticles for Ischemic Stroke Therapy.
Liquid-liquid phase separation of RBM33 facilitates hippocampus aging by inducing microglial senescence by activating CDKN1A.
Hydromethylthionine sustains truncated tau-dependent inflammation-lowering effects in mouse brain.
PARP14 inhibits microglial activation via NNT to alleviate depressive-like behaviors in mice.
Loading tea polyphenols enhances the repair of human umbilical cord mesenchymal stem cell sheet after spinal cord injury.
Complement C4 exacerbates astrocyte-mediated neuroinflammation and promotes α-synuclein pathology in Parkinson's disease.
Neuroprotective potential of tranilast in streptozotocin-induced sporadic Alzheimer's disease model targeting TXNIP-NLRP3 inflammasome pathway.
Multiomics reveal biomolecular shifts and ER stress in sleep-restricted women affecting NSC functions.
FOXG1 Improves Cognitive Function in Alzheimer's Disease by Promoting Endogenous Neurogenesis.
DANCR knockdown alleviates neuroinflammation and functional recovery after spinal cord injury via regulating the ACTN4 / STAT3 axis.
Glial scarring limits recovery following decompressive surgery in rats with syringomyelia.
Aerobic exercise improves clearance of amyloid-β via the glymphatic system in a mouse model of Alzheimer's Disease.
Vagus nerve stimulation inhibits PANoptosis and promotes neurofunctional recovery of cerebral ischemic stroke in a Sirt1-dependent manner.
Endogenous TDP-43 mislocalization in a novel knock-in mouse model reveals DNA repair impairment, inflammation, and neuronal senescence.
Single-cell analysis reveals that GFAP(+) dedifferentiated Schwann cells promote tumor progress in PNI-positive distal cholangiocarcinoma via lactate/HMGB1 axis.
Connexin 43 is downregulated in advanced Parkinson's disease in multiple brain regions which correlates with symptoms.
Intranasal Delivery of Hydrophobic AC5216 Loaded Nanoemulsion into Brain To Alleviate Chronic Unpredictable Stress-Induced Depressive-like Behaviors.
Intracellular metabotropic glutamate receptor 5 in spinal dorsal horn neurons contributes to pain in a mouse model of vincristine-induced neuropathic pain.
Astrocytic pleiotrophin deficiency in the prefrontal cortex contributes to stress-induced depressive-like responses in male mice.
Intranasal oxytocin alleviates postsurgical pain and comorbid anxiety in mice: Participation of BK(Ca) channels in the hippocampus.
Ceftriaxone affects ferroptosis and alleviates glial cell activation in Parkinson's disease.
TNF-α mediates activation of neuronal necroptotic signaling in rat with syringomyelia.
Allopregnanolone relieves paclitaxel induced mechanical hypersensitivity via inhibiting spinal cord PGE(2)-EP2 mediated microglia-neuron signaling.
GPR43 regulates mitochondrial apoptosis through the cyclophilin D pathway in Alzheimer's disease.
Photobiomodulation mitigates blood-brain barrier disruption in APP/PS1 mouse model of Alzheimer's disease by activating the AMPK pathway.
A Multifunctional Electrochemical Biosensor Based on Near-Infrared Light-Responsive Hydrogel for In Vivo Recording and Modulation.
CircITSN1/EIF4A3/Itsn1 axis mediates postoperative cognitive dysfunction in aged mice: A novel mechanism and therapeutic target.
Mesenchymal Stem Cell-Derived Mitochondrial Transfer Promotes Tip Cell Phenotype via Glutathione Metabolic Reprogramming in Stroke Mice.
Spatiotemporal transcriptomic maps of mouse intracerebral hemorrhage at single-cell resolution.
Vagus nerve stimulation inhibits pyroptosis and improves outcome of cerebral ischemic stroke by upregulating osteopontin (SPP1) to disturb ASC oligomerization.
Magnetically Driven Biomimetic Microrobot Loaded with Eleutheroside B for Targeted Delivery and Neural Repair in Spinal Cord Injury.
Exploring Core Genes Involved in Ischemic Stroke and the Therapeutic Potential of Hyperbaric Oxygen: Insights from Transcriptomic Analysis.
Periodontitis-induced neuroinflammation triggers IFITM3-Aβ axis to cause alzheimer's disease-like pathology and cognitive decline.
Integrating scRNA-seq to explore offspring neurodevelopmental toxicity induced by Cyfluthrin exposure during pregnancy: A fate decision for NSCs.
Selective Activation of G Protein-Coupled Estrogen Receptor 1 (GPER1) Reduces ER Stress and Pyroptosis via AMPK Signaling Pathway in Experimental Subarachnoid Hemorrhage.
SENP1 inhibits aerobic glycolysis in Aβ(1-42)-incubated astrocytes by promoting PUM2 deSUMOylation.
Microglia-derived Galectin-9 drives amyloid-β pathology in Alzheimer's disease.
Endothelial AGGF1 promotes retinal angiogenesis by coordinating TNFSF12/FN14 signalling.
Mesenchymal stem cells overexpressing neuropeptide S promote the recovery of rats with spinal cord injury by activating the PI3K/AKT/GSK3β signaling pathway.
Serum-tolerant polymeric complex for stem-cell transfection and neural differentiation.
Mogroside V ameliorates astrocyte inflammation induced by cerebral ischemia through suppressing TLR4/TRADD pathway.
PD-1 Attenuates Neuropathic Pain by Ameliorating NLRP3 Inflammasome-Mediated Microglia Pyroptosis.
Redirecting the route: Monocyte-mediated delivery of oHSV-1 across a human BBB-on-chip model.
HCN2 promotes neurodevelopmental and synaptic function repair through the CaMKII/CREB pathway to alleviate general anesthesia-induced cognitive impairment.
VSIG2 as a novel immunosuppressive ligand interacts with Nectin-2 to regulate T cell responses.
Ectomesenchymal Stem Cell Transplantation Induces Microglial Polarization and Anti-inflammatory IL-10 Secretion via NF-κB and MAPK Pathways to Mitigate Brain Injury Post-cerebral Hemorrhage.
Galectin-9 activates microglial asparagine endopeptidase and promotes α-synuclein pathology in Parkinson's disease.
Omega-3 Polyunsaturated Fatty Acids Prevent Sevoflurane-induced Cognitive and Fine Motor Dysfunctions in Neonatal Mice by Enhancing Phosphorylated Tau Glymphatic System Clearance Pathway.
Aberrant neuronal excitation promotes neuroinflammation in the primary motor cortex of ischemic stroke mice.
Fibrinogen regulates microglial function through the JAK2/STAT3 signaling pathway.
Edaravone ameliorates inflammation in ischemic stroke mouse by regulating the CYP1A1 pathway through gut microbiota.
Purinergic P2X7 receptor involves in anti-retinal photodamage effects of berberine.
Neuroprotective effects of Yangming-Kaixin-Yizhi formula in Alzheimer's disease: dual regulation of PI3K/Akt and p38 MAPK signaling via network pharmacology and experimental approaches.
Deletion of SH2D5 alleviates epileptic seizures and NMDAR expression via autophagic degradation of STAT1.
Sex-specific neurotoxicity induced by long-term bisphenol A exposure: Single-cell sequencing reveals dual mechanisms involving hippocampal gliosis and neuronal apoptosis.
USP18 is a key regulator of immune function in mouse midbrain microglia.
Electroacupuncture at 5/100 Hz alleviates neuropathic pain in rats by inhibiting the CCL3/CCR5 axis in the spinal cord.
Astaxanthin alleviates spinal nerve ligation-induced neuropathic pain by modulating propionic acid levels.
Accumulation of Damaging Lipids in the Arf1-Ablated Neurons Promotes Neurodegeneration through Releasing mtDNA and Activating Inflammatory Pathways in Microglia.
Photobiomodulation modulates mitochondrial energy metabolism and ameliorates neurological damage in an APP/PS1 mousmodel of Alzheimer's disease.
Ubiquitination-mediated upregulation of glycolytic enzyme MCT4 in promoting astrocyte reactivity during neuroinflammation.
Neuroinflammation and hypoxia promote astrocyte phenotypic transformation and propel neurovascular dysfunction in brain arteriovenous malformation.
Ticagrelor alleviates neuroinflammation after traumatic brain injury by inhibiting NLRP3 inflammasome-mediated pyroptosis.
Anxiolytic effects of accelerated continuous theta burst stimulation on mice exposed to chronic restraint stress and the underlying mechanism involving gut microbiota.
M1 Microglia-Derived Exosomes Promote A1 Astrocyte Activation and Aggravate Ischemic Injury via circSTRN3/miR-331-5p/MAVS/NF-κB Pathway.
Liquiritin ameliorates painful diabetic neuropathy in SD rats by inhibiting NLRP3-MMP-9-mediated reversal of aquaporin-4 polarity in the glymphatic system.
S1P/S1PR1 signaling is involved in the development of nociceptive pain.
TAK1 inhibition mitigates intracerebral hemorrhage-induced brain injury through reduction of oxidative stress and neuronal pyroptosis via the NRF2 signaling pathway.
Astrocyte activation in hindlimb somatosensory cortex contributes to electroacupuncture analgesia in acid-induced pain.
Circular RNA SCMH1 suppresses KMO expression to inhibit mitophagy and promote functional recovery following stroke.
Microglia and Astrocytes Responses Contribute to Alleviating Inflammatory Damage by Repetitive Transcranial Magnetic Stimulation in Rats with Traumatic Brain Injury.
The necessity of eliminating the interference of panaxatriol saponins to maximize the preventive effect of panaxadiol saponins against Parkinson's disease in rats.
Tirzepatide shows neuroprotective effects via regulating brain glucose metabolism in APP/PS1 mice.
Sestrin2 remedies neuroinflammatory response by inhibiting A1 astrocyte conversion via autophagy.
Scavenger Receptor Class B Type I Modulates Epileptic Seizures and Receptor α2δ-1 Expression.
Three-Dimensional Culture of Glioblastoma Cells Using a Tissueoid Cell Culture System.
USP9X-mediated deubiquitination of Raptor contributes to autophagy impairment and memory deficits in P301S mice.
Targeted Microglial Membrane-Coated MicroRNA Nanosponge Mediates Inhibition of Glioblastoma.
An accelerated Parkinson's disease monkey model using AAV-α-synuclein plus poly(ADP-ribose).
Targeting exosomal double-stranded RNA-TLR3 signaling pathway attenuates morphine tolerance and hyperalgesia.
Human amniotic epithelial cells improve uterine spiral artery remodeling to ameliorate preeclampsia in a rat model†.
Cynarin inhibits microglia-induced pyroptosis and neuroinflammation via Nrf2/ROS/NLRP3 axis after spinal cord injury.
Shh regulates M2 microglial polarization and fibrotic scar formation after ischemic stroke.
Hypoxanthine Produces Rapid Antidepressant Effects by Suppressing Inflammation in Serum and Hippocampus.
Catalpol regulates apoptosis and proliferation of endothelial cell via activating HIF-1α/VEGF signaling pathway.
Whole-body vibration elicits 40 Hz cortical gamma oscillations and ameliorates age-related cognitive impairment through hippocampal astrocyte synapses in male rats.
Transcriptional landscape of the interaction of human Mesenchymal Stem Cells with Glioblastoma in bioprinted co-cultures.
A Histopathologic Correlation Study Evaluating Glymphatic Function in Brain Tumors by Multiparametric MRI.
Development of a time-resolved immunochromatographic test strip for rapid and quantitative determination of GFAP in serum.
Let-7b-TLR7 Signaling Axis Contributes to the Anesthesia/Surgery-Induced Cognitive Impairment.
Inhibition of aquaporin-4 and its subcellular localization attenuates below-level central neuropathic pain by regulating astrocyte activation in a rat spinal cord injury model.
Inhibition of OGFOD1 by FG4592 confers neuroprotection by activating unfolded protein response and autophagy after ischemic stroke.
The Effect of Reduced Fibrinogen on Cerebrovascular Permeability during Traumatic Brain Injury in Fibrinogen Gene Heterozygous Knockout Mice.
Endogenous TDP-43 mislocalization in a novel knock-in mouse model reveals DNA repair impairment, inflammation, and neuronal senescence.
Down-regulating nuclear factor of activated T cells 1 alleviates cognitive deficits in a mouse model of sepsis-associated encephalopathy, possibly by stimulating hippocampal neurogenesis.
Enhancing stem cell therapy efficacy with functional lignin modified cerium-iron nanozyme through magnetic resonance imaging tracking and apoptosis protection in inflammatory environment.
Culture of cerebrospinal fluid-contacting neurons from neonatal mouse spinal cord.
MYPT1(SMKO) Mice Function as a Novel Spontaneous Age- and Hypertension-Dependent Animal Model of CSVD.
Ginkgolide B can alleviate spinal cord glymphatic system dysfunction and provide neuroprotection in painful diabetic neuropathy rats by inhibiting matrix metalloproteinase-9.
CHCHD10(S59L/+) mouse model: Behavioral and neuropathological features of frontotemporal dementia.
Inhibition of TREM-1 alleviates neuroinflammation by modulating microglial polarization via SYK/p38MAPK signaling pathway after traumatic brain injury.
Small Extracellular Vesicles Derived from Altered Peptide Ligand-Loaded Dendritic Cell Act as A Therapeutic Vaccine for Spinal Cord Injury Through Eliciting CD4(+) T cell-Mediated Neuroprotective Immunity.
Pathological features and molecular signatures of early olfactory dysfunction in 3xTg-AD model mice.
Human umbilical cord derived mesenchymal stem cells overexpressing HO-1 attenuate neural injury and enhance functional recovery by inhibiting inflammation in stroke mice.
OPTN gene therapy increases autophagy and protects mitochondria in SOD1-G93A-expressing transgenic mice and cells.
Innate immune sensing of lysosomal dysfunction drives multiple lysosomal storage disorders.
RNF220-mediated K63-linked polyubiquitination stabilizes Olig proteins during oligodendroglial development and myelination.
Berberine modulates microglial polarization by activating TYROBP in Alzheimer's disease.
Avicularin inhibits ferroptosis and improves cognitive impairments in Alzheimer's disease by modulating the NOX4/Nrf2 axis.
Ku70 silencing aggravates oxygen-glucose deprivation/reperfusion-induced injury by activation of the p53 apoptotic pathway in rat cortical astrocytes.
The Phenotype Changes of Astrocyte During Different Ischemia Conditions.
β-hydroxybutyrate alleviates neurological deficits by restoring glymphatic and inflammation after subarachnoid hemorrhage in mice.
Effects of nanoplastic exposure during pregnancy and lactation on neurodevelopment of rat offspring.
GDI2 deletion alleviates neurodegeneration and memory loss in the 5xFAD mice model of Alzheimer's disease.
Engagement of N(6)-methyladenisine methylation of Gng4 mRNA in astrocyte dysfunction regulated by CircHECW2.
Miniaturized Implantable Fluorescence Probes Integrated with Metal-Organic Frameworks for Deep Brain Dopamine Sensing.
Neuron-targeted liposomal coenzyme Q10 attenuates neuronal ferroptosis after subarachnoid hemorrhage by activating the ferroptosis suppressor protein 1/coenzyme Q10 system.
A mosquito mouthpart-like bionic neural probe.
Peroxiredoxin 2 Is a Potential Objective Indicator for Severity and the Clinical Status of Subarachnoid Hemorrhage Patients.
Levomilnacipran ameliorates lipopolysaccharide-induced depression-like behaviors and suppressed the TLR4/Ras signaling pathway.
Alleviating symptoms of neurodegenerative disorders by astrocyte-specific overexpression of TMEM164 in mice.
Clemastine fumarate attenuates tauopathy and meliorates cognition in hTau mice via autophagy enhancement.
Enrofloxacin hydrochloride toxicological effects on crucian carp reflected by serological changes and neurotoxicity.
ChemR23 activation attenuates cognitive impairment in chronic cerebral hypoperfusion by inhibiting NLRP3 inflammasome-induced neuronal pyroptosis.
Losartan attenuates acetic acid enema-induced visceral hypersensitivity by inhibiting the ACE1/Ang II/AT1 receptor axis in enteric glial cells.
ARL6IP1 mediates small-molecule-induced alleviation of Alzheimer pathology through FXR1-dependent BACE1 translation initiation.
Thioredoxin 1 overexpression attenuated diabetes-induced endoplasmic reticulum stress in Müller cells via apoptosis signal-regulating kinase 1.
Mechanistic Insights into the Role of OPN in Mediating Brain Damage via Triggering Lysosomal Damage in Microglia/Macrophage.
Anti-CHAC1 exosomes for nose-to-brain delivery of miR-760-3p in cerebral ischemia/reperfusion injury mice inhibiting neuron ferroptosis.
The ZSWIM8 ubiquitin ligase regulates neurodevelopment by guarding the protein quality of intrinsically disordered Dab1.
Neuronal loss of NCLX-dependent mitochondrial calcium efflux mediates age-associated cognitive decline.
Syntaxin 7 modulates seizure activity in epilepsy.
Enhanced BPGM/2,3-DPG pathway activity suppresses glycolysis in hypoxic astrocytes via FIH-1 and TET2.
Neurogranin as an important regulator in swimming training to improve the spatial memory dysfunction of mice with chronic cerebral hypoperfusion.
Taxifolin attenuates neuroinflammation and microglial pyroptosis via the PI3K/Akt signaling pathway after spinal cord injury.
3D Gelatin Microsphere Scaffolds Promote Functional Recovery after Spinal Cord Hemisection in Rats.
Transcription factor ETS proto-oncogene 1 contributes to neuropathic pain by regulating histone deacetylase 1 in primary afferent neurons.
Golgi damage caused by dysfunction of PiT-2 in primary familial brain calcification.
Negative regulation of TREM2-mediated C9orf72 poly-GA clearance by the NLRP3 inflammasome.
Development of Brain-Derived Bioscaffolds for Neural Progenitor Cell Culture.
Neurotoxic A1 astrocytes promote neuronal ferroptosis via CXCL10/CXCR3 axis in epilepsy.
Extracellular RNAs-TLR3 signaling contributes to cognitive impairment after chronic neuropathic pain in mice.
Senile plaques in Alzheimer's disease arise from Aβ- and Cathepsin D-enriched mixtures leaking out during intravascular haemolysis and microaneurysm rupture.
Electroacupuncture-Regulated miR-34a-3p/PDCD6 Axis Promotes Post-Spinal Cord Injury Recovery in Both In Vitro and In Vivo Settings.
Dexmedetomidine Can Enhance PINK1/Parkin-Mediated Mitophagy in MPTP-Induced PD Mice Model by Activating AMPK.
Downregulation of m6A Methyltransferase in the Hippocampus of Tyrobp (-/-) Mice and Implications for Learning and Memory Deficits.
Galectin-9/Tim-3 pathway mediates dopaminergic neurodegeneration in MPTP-induced mouse model of Parkinson's disease.
Nanoformulated Bumetanide Ameliorates Social Deficiency in BTBR Mice Model of Autism Spectrum Disorder.
AQP2 Promotes Astrocyte Activation by Modulating the TLR4/NFκB-p65 Pathway Following Intracerebral Hemorrhage.
Combined cell grafting and VPA administration facilitates neural repair through axonal regeneration and synaptogenesis in traumatic brain injury.
Exogenous TIPE2 Inhibit TAK1 to Improve Inflammation and Neuropathic Pain Induced by Sciatic Nerve Injury Through Inactivating NF-κB and JNK.
Blood-brain barrier permeability to enrofloxacin in Pengze crucian carp (Carassius auratus var. Pengze).
FOXG1 Contributes Adult Hippocampal Neurogenesis in Mice.
Dexmedetomidine alleviates pain in MPTP-treated mice by activating the AMPK/mTOR/NF-κB pathways in astrocytes.
The effect of prolonged formalin fixation on the expression of proteins in human brain tissues.
Seizures in PPT1 Knock-In Mice Are Associated with Inflammatory Activation of Microglia.
Repair of Spinal Cord Injury by Inhibition of PLK4 Expression Through Local Delivery of siRNA-Loaded Nanoparticles.
The circadian clock protein Rev-erbα provides neuroprotection and attenuates neuroinflammation against Parkinson's disease via the microglial NLRP3 inflammasome.
Pancreatic Stellate Cells Prolong Ex Vivo Islet Viability and Function and Improve Engraftment.
Indole-3-propionic acid alleviates ischemic brain injury in a mouse middle cerebral artery occlusion model.
Sigma-1 receptor activation alleviates blood-brain barrier disruption post cerebral ischemia stroke by stimulating the GDNF-GFRα1-RET pathway.
Extracellular vesicle-mediated delivery of circDYM alleviates CUS-induced depressive-like behaviours.
Islet amyloid polypeptide cross-seeds tau and drives the neurofibrillary pathology in Alzheimer's disease.
Astrocytic VEGFA: An essential mediator in blood-brain-barrier disruption in Parkinson's disease.
High, in Contrast to Low Levels of Acute Stress Induce Depressive-like Behavior by Involving Astrocytic, in Addition to Microglial P2X7 Receptors in the Rodent Hippocampus.
Fine-tuning of mTOR signaling by the UBE4B-KLHL22 E3 ubiquitin ligase cascade in brain development.
Spatial transcriptomics shows moxibustion promotes hippocampus astrocyte and neuron interaction.
Fucoidan ameliorates LPS-induced neuronal cell damage and cognitive impairment in mice.
Cornuside Is a Potential Agent against Alzheimer's Disease via Orchestration of Reactive Astrocytes.
Multifunctional chitin-based hollow nerve conduit for peripheral nerve regeneration and neuroma inhibition.
CUMS and dexamethasone induce depression-like phenotypes in mice by differentially altering gut microbiota and triggering macroglia activation.
Destructive Effects of Pyroptosis on Homeostasis of Neuron Survival Associated with the Dysfunctional BBB-Glymphatic System and Amyloid-Beta Accumulation after Cerebral Ischemia/Reperfusion in Rats.
The Neural Stem Cell Properties of PKD2L1(+) Cerebrospinal Fluid-Contacting Neurons in vitro.
L-Cysteine Provides Neuroprotection of Hypoxia-Ischemia Injury in Neonatal Mice via a PI3K/Akt-Dependent Mechanism.
Quantitative Proteomics Reveals the Dynamic Pathophysiology Across Different Stages in a Rat Model of Severe Traumatic Brain Injury.
Agomelatine Prevents Amyloid Plaque Deposition, Tau Phosphorylation, and Neuroinflammation in APP/PS1 Mice.
Fascin-1 is Highly Expressed Specifically in Microglia After Spinal Cord Injury and Regulates Microglial Migration.
Reconstituting neurovascular unit with primary neural stem cells and brain microvascular endothelial cells in three-dimensional matrix.
High-speed, cortex-wide volumetric recording of neuroactivity at cellular resolution using light beads microscopy.
The role of cell-free DNA in fibrinolysis for intraventricular hemorrhage.
Wnt10a/β-catenin signalling is involved in kindlin-1-mediated astrocyte activation in a chronic construction injury rat model.
Stanniocalcin-1 Protected Astrocytes from Hypoxic Damage Through the AMPK Pathway.
Effects of Chronic Secondhand Smoke (SHS) Exposure on Cognitive Performance and Metabolic Pathways in the Hippocampus of Wild-Type and Human Tau Mice.
Restoration of CTSD (cathepsin D) and lysosomal function in stroke is neuroprotective.
UBQLN2-HSP70 axis reduces poly-Gly-Ala aggregates and alleviates behavioral defects in the C9ORF72 animal model.
A Multichannel Flexible Optoelectronic Fiber Device for Distributed Implantable Neurological Stimulation and Monitoring.
Genetic deletion of Rnd3 suppresses apoptosis through NF‑κB signaling in the brain.
3-Hydroxybenzaldehyde and 4-Hydroxybenzaldehyde enhance survival of mouse astrocytes treated with Angiostrongylus cantonensis young adults excretory/secretory products.
KAT1 triggers YTHDF2-mediated ITGB1 mRNA instability to alleviate the progression of diabetic retinopathy.
Injectable Gelatin Hydrogel Suppresses Inflammation and Enhances Functional Recovery in a Mouse Model of Intracerebral Hemorrhage.
Effects of Ginkgo biloba on Early Decompression after Spinal Cord Injury.
Nrf2 Ablation Promotes Alzheimer's Disease-Like Pathology in APP/PS1 Transgenic Mice: The Role of Neuroinflammation and Oxidative Stress.
Effects of Xiaoyaosan on Depressive-Like Behaviors in Rats With Chronic Unpredictable Mild Stress Through HPA Axis Induced Astrocytic Activities.
Autophagic degradation of PML promotes susceptibility to HSV-1 by stress-induced corticosterone.
Effects of seawater immersion on open traumatic brain injury in rabbit model.
Mesenchymal stromal cell-derived extracellular vesicles modulate microglia/macrophage polarization and protect the brain against hypoxia-ischemic injury in neonatal mice by targeting delivery of miR-21a-5p.
Annexin A7 induction of neuronal apoptosis via effect on glutamate release in a rat model of subarachnoid hemorrhage.
Bexarotene Improve Depression-Like Behaviour in Mice by Protecting Against Neuro-inflammation and Synaptic Damage.
The LncRNA H19/miR-1-3p/CCL2 axis modulates lipopolysaccharide (LPS) stimulation-induced normal human astrocyte proliferation and activation.
Brain-derived neurotrophic factor and Glial cell line-derived neurotrophic factor expressions in the trigeminal root entry zone and trigeminal ganglion neurons of a trigeminal neuralgia rat model.
Pentraxin 3 contributes to neurogenesis after traumatic brain injury in mice.
FSHR ablation induces depression-like behaviors.
STK24 modulates excitatory synaptic transmission in epileptic hippocampal neurons.
L-Cysteine-Derived H(2)S Promotes Microglia M2 Polarization via Activation of the AMPK Pathway in Hypoxia-Ischemic Neonatal Mice.
Inhibition of Nwd1 activity attenuates neuronal hyperexcitability and GluN2B phosphorylation in the hippocampus.
Interleukin-6: Its role and mechanisms in rescuing depression-like behaviors in rat models of depression.
Silencing Huwe1 reduces apoptosis of cortical neurons exposed to oxygen-glucose deprivation and reperfusion.
Glutamate affects the CYP1B1- and CYP2U1-mediated hydroxylation of arachidonic acid metabolism via astrocytic mGlu5 receptor.
Neuroprotective effects of matrix metalloproteinases in cerebral ischemic rats by promoting activation and migration of astrocytes and microglia.
Dynamic cell type-specific expression of Nrf2 after traumatic brain injury in mice.
Mesenchymal stem cell derived EVs mediate neuroprotection after spinal cord injury in rats via the microRNA-21-5p/FasL gene axis.
Icariin Ameliorates Amyloid Pathologies by Maintaining Homeostasis of Autophagic Systems in Aβ(1-42)-Injected Rats.
COX-2 inhibition rescues depression-like behaviors via suppressing glial activation, oxidative stress and neuronal apoptosis in rats.
Extracellular RNAs-TLR3 signaling contributes to cognitive decline in a mouse model of postoperative cognitive dysfunction.
Glial Plasticity in the Trigeminal Root Entry Zone of a Rat Trigeminal Neuralgia Animal Model.
Resistin-Inhibited Neural Stem Cell-Derived Astrocyte Differentiation Contributes to Permeability Destruction of the Blood-Brain Barrier.
Methylene blue offers neuroprotection after intracerebral hemorrhage in rats through the PI3K/Akt/GSK3β signaling pathway.
Targeting Smox Is Neuroprotective and Ameliorates Brain Inflammation in Cerebral Ischemia/Reperfusion Rats.
Xanthoceraside modulates neurogenesis to ameliorate cognitive impairment in APP/PS1 transgenic mice.
Limb remote ischemic postconditioning protects integrity of the blood-brain barrier after stroke.
l-Cysteine suppresses hypoxia-ischemia injury in neonatal mice by reducing glial activation, promoting autophagic flux and mediating synaptic modification via H(2)S formation.
GPR40 modulates epileptic seizure and NMDA receptor function.
KPNB1 inhibition disrupts proteostasis and triggers unfolded protein response-mediated apoptosis in glioblastoma cells.
CD4+ αβ T cell infiltration into the leptomeninges of lumbar dorsal roots contributes to the transition from acute to chronic mechanical allodynia after adult rat tibial nerve injuries.
Inhibition of Cdk5 rejuvenates inhibitory circuits and restores experience-dependent plasticity in adult visual cortex.
RNF20 controls astrocytic differentiation through epigenetic regulation of STAT3 in the developing brain.
Apolipoprotein E Exerts a Whole-Brain Protective Property by Promoting M1? Microglia Quiescence After Experimental Subarachnoid Hemorrhage in Mice.
Hippocampal CA1 βCaMKII mediates neuroinflammatory responses via COX-2/PGE2 signaling pathways in depression.
HIF-1α is Critical for the Activation of Notch Signaling in Neurogenesis During Acute Epilepsy.
Transcriptome-Wide Identification of Differentially Expressed Genes and Long Non-coding RNAs in Aluminum-Treated Rat Hippocampus.
The BAF45D Protein Is Preferentially Expressed in Adult Neurogenic Zones and in Neurons and May Be Required for Retinoid Acid Induced PAX6 Expression.
Activation inhibitors of nuclear factor kappa B protect neurons against the NMDA-induced damage in the rat retina.
Antibody incubation at 37°C improves fluorescent immunolabeling in free-floating thick tissue sections.
Methylene Blue promotes cortical neurogenesis and ameliorates behavioral deficit after photothrombotic stroke in rats.
Gadd45b prevents autophagy and apoptosis against rat cerebral neuron oxygen-glucose deprivation/reperfusion injury.
Huwe1 interacts with Gadd45b under oxygen-glucose deprivation and reperfusion injury in primary Rat cortical neuronal cells.
Cell-density-dependent manifestation of partial characteristics for neuronal precursors in a newly established human gliosarcoma cell line.
Transplantation of mesenchymal stem cells exerts anti-apoptotic effects in adult rats after spinal cord ischemia-reperfusion injury.
Protein tyrosine phosphatase receptor U (PTPRU) is required for glioma growth and motility.
Ming Z, Liu Y, Jia S, Su Y, Yan W, Lin J
Frontiers in immunology 2026;17:1750051
Frontiers in immunology 2026;17:1750051
Integrating network pharmacology and transcriptomics to reveal the therapeutic effect of Long Mu Ning Xin Decoction on attention-deficit/hyperactivity disorder by regulating cAMP and PI3K/AKT pathways.
Ren X, Ding L, Jiang Y
Frontiers in pharmacology 2026;17:1744709
Frontiers in pharmacology 2026;17:1744709
Microvascular endothelial metabolic dysfunction drives cerebral edema through bioenergetic failure after ischemia-reperfusion.
Zhou YF, Yang SB, Zhang F, Sun XD, Chang BH, Li YN, Wu JH, Jin HJ, Huang M, Chen SC, Yang H, Zhu DY, Menon BK, Hu B
Theranostics 2026;16(7):3577-3598
Theranostics 2026;16(7):3577-3598
PTBP1-mediated inhibition of circular RNA SCMH1 biogenesis impairs brain recovery after ischemic stroke.
Bai Y, Han B, Zhang Y, Wen L, Liu C, Wang Y, Cui J, Zheng B, Cai N, Xu L, Shen L, Zhang Y, Yao H
Theranostics 2026;16(1):239-253
Theranostics 2026;16(1):239-253
P2X7 receptor-mediated cGAS-STING pathway activation underlies chronic stress-induced depressive-like behaviors.
He XM, Zhang Y, Chen CY, Tang YH, Li X
Purinergic signalling 2026 Mar 30;22(2)
Purinergic signalling 2026 Mar 30;22(2)
Reduced nuclear TDP-43 and cytoplasmic DLK1 as markers of motor neuron degeneration in amyotrophic lateral sclerosis.
Takeda T, Ishikawa A, Kokubun S, Saito Y, Isose S, Ito K, Arai K, Kuwabara S, Honda K
Journal of neuropathology and experimental neurology 2026 Mar 19;
Journal of neuropathology and experimental neurology 2026 Mar 19;
Modulating GRP75 to restore calcium homeostasis: a novel neuroprotective strategy of CRSE6(#) in Parkinson's disease models.
Wang X, Li S, Xiang X, Zhang X, Yu C, Qing D, Law BY, Tang Y
Journal of advanced research 2026 Mar 19;
Journal of advanced research 2026 Mar 19;
Investigating the Effect and Mechanism of Protocatechuic Aldehyde on Vascular Dementia Based on Multi-Omics Approach.
Xiao T, Tao J, Tan J, Yi X, Wang Z, Duan X
Biomolecules 2026 Mar 11;16(3)
Biomolecules 2026 Mar 11;16(3)
Glibenclamide Attenuates Brain Edema After Intracerebral Hemorrhage Through Preservation of Blood-Brain Barrier Integrity and Glymphatic Function.
Du C, Wu Y, Geng Y, Ali A, Li Z, Liu Z, Ma C
Neurochemical research 2026 Mar 10;51(2)
Neurochemical research 2026 Mar 10;51(2)
The engineered probiotic strain Lactococcus lactis MG1363-pMG36e-GLP-1 regulates microglial polarization and gut dysbiosis in a transgenic mouse model of Parkinson's disease.
Yue M, Chen T, Chen W, Wei J, Liao B, Zhang J, Li F, Hong D, Fang X
Neural regeneration research 2026 Mar 1;21(3):1211-1221
Neural regeneration research 2026 Mar 1;21(3):1211-1221
Phosphodiesterase 4 regulates pyroptosis in subarachnoid hemorrhage.
Tan J, Ma Y, Song R, Ye H, Su J, He Z
Neural regeneration research 2026 Jun 1;21(6):2609-2620
Neural regeneration research 2026 Jun 1;21(6):2609-2620
Astrocyte-Specific Nrf2 Expression Transforms Neurotoxic Reactive Astrocytes to Neuroprotective Phenotype in 3xTg-AD Mice.
Guo S, Wei F, Sun H, Jin H, Cheng W, Fu C, Wang H, Yin Y
Glia 2026 Jan;74(1):e70087
Glia 2026 Jan;74(1):e70087
Early astrocyte-targeted intervention guided by (18)F-SMBT-1 imaging attenuates disease progression in 3xTg-AD mice.
Guo S, Wei F, Chang Y, Wu S, Lou Z, Ma Y, Huang Q, He K, Fu C, Cao X, Liang S, Cheng W, Yin Y
European journal of nuclear medicine and molecular imaging 2026 Feb;53(3):2034-2046
European journal of nuclear medicine and molecular imaging 2026 Feb;53(3):2034-2046
Decorin Attenuates Epileptogenesis and Modulates Hippocampal Synaptic Plasticity via the mTOR Signalling Pathway.
Liu Z, Shen Y, Luo AD, Ao WL, Guan SQ, Lei F, Xu ZC, Yu CY, Xu P, Huang H
Neurochemical research 2026 Feb 17;51(2):74
Neurochemical research 2026 Feb 17;51(2):74
Astrocytic LCN2 drives neuronal dysfunction in epilepsy by suppressing tunnel nanotube-mediated mitochondrial transfer via NLRP3 inflammasome activation.
Zhou Z, Zhang P, Jiang Y, Xu Y, Liu F, Chen X, Chen D, Tang W, Liao R, Liu L
Free radical biology & medicine 2026 Feb 16;244:84-106
Free radical biology & medicine 2026 Feb 16;244:84-106
The promoting roles of GLP1R and GIPR in stemness maintenance and multiple lineage-specific differentiation of PDLSCs.
Shen Y, Zhang M, Yang T, Wu Y, Qiu Y, Zhang L, Li F, Chen M, Chen Q, Wei W, Li H, Shen Y
Cellular & molecular biology letters 2026 Feb 11;31(1):22
Cellular & molecular biology letters 2026 Feb 11;31(1):22
Fibrotic scar formation after cerebral ischemic stroke: Targeting the Sonic hedgehog signaling pathway for scar reduction.
Wen J, Tang H, Tian M, Wang L, Yang Q, Zhao Y, Li X, Ren Y, Wang J, Zhou L, Tan Y, Wu H, Cai X, Wang Y, Cao H, Xu J, Yang Q
Neural regeneration research 2026 Feb 1;21(2):756-768
Neural regeneration research 2026 Feb 1;21(2):756-768
Integrated multi-omics analysis identifies potential therapeutic targets for Alzheimer's disease.
Li H, Kang J, Liang Z, Wang X, Zhu L, Tang H, Peng W
Neural regeneration research 2026 Aug 1;21(8):3769-3778
Neural regeneration research 2026 Aug 1;21(8):3769-3778
Intermittent theta-burst stimulation promotes neurovascular unit remodeling after ischemic stroke in a mouse model.
Zhang J, Ding M, Luo L, Huang D, Li S, Chen S, Fan Y, Liu L, Xie H, Liu G, Yu K, Wu J, Xiao X, Wu Y
Neural regeneration research 2026 Aug 1;21(8):3598-3608
Neural regeneration research 2026 Aug 1;21(8):3598-3608
Shh-S100A10 axis curbs neuronal PANoptosis after ischemic stroke.
Wang L, Tang H, Wen J, Yang Q, Huang J, Zhao Y, Ren Y, Yang Q
Neural regeneration research 2026 Aug 1;21(8):3579-3587
Neural regeneration research 2026 Aug 1;21(8):3579-3587
YAP Regulates Microglial Anti-Inflammatory Responses and Alleviates Cognitive Impairment Through the IL-33/ST2 Pathway after Traumatic Brain Injury.
Zhao R, Gao SQ, Wang X, Li T, Gao CC, Han YL, Qiu JY, Miao SH, Sun Y, Zheng XB, Jin WX, Zhou ML
Journal of neurotrauma 2026 Apr;43(7-8):641-659
Journal of neurotrauma 2026 Apr;43(7-8):641-659
Neuro-bone-skin tri-regeneration via a microenvironment-responsive PRP-loaded chitosan hydrogel for traumatic brain injury therapy.
Yang W, Su Y, Wang H, Liu P, Cheng P, Zhao H, He Y, Liu Y, Ma S, Guan F, Yao M
Materials today. Bio 2026 Apr;37:102913
Materials today. Bio 2026 Apr;37:102913
Modulation of glutamate metabolic reprogramming via Ras-Raf-MEK/ERK signaling alleviates immune inflammation of astrocytes in glaucomatous neurodegeneration.
Wang X, Tan S, Mou Z, Zheng Y, Yuan J, Zeng L, Wei M, Ouyang R, Fan X, Huo Y, Pu Y, Lei J, Gao X, Wang D, Peng Y, Li H
Free radical biology & medicine 2026 Apr;247:469-485
Free radical biology & medicine 2026 Apr;247:469-485
Identification of Fibrinogen C Domain-Containing protein 1 (FIBCD1) as a novel target for treatment of Post-Traumatic stress disorder (PTSD) and discovery of a novel FIBCD1 inhibitor.
Ma S, Wang Z, Zhang F, Zhang H
Brain, behavior, and immunity 2026 Apr 20;136:106775
Brain, behavior, and immunity 2026 Apr 20;136:106775
Engineered Alzheimer Organoids Validate the Link Between Intracellular and Soluble p-Tau Biomarkers and Highlight the Contribution of Astrocytic Tau.
Zhang R, Dong X, Pei G, Huang S
Neuroscience bulletin 2026 Apr 11;
Neuroscience bulletin 2026 Apr 11;
Injectable Brain Extracellular Matrix Hydrogels Enhance Neuronal Migration and Functional Recovery After Intracerebral Hemorrhage.
Xia J, Gao X, Yao J, Fei Y, Song D, Gu Z, Zheng G, Gu Y, Tu C
Biomaterials research 2025;29:0192
Biomaterials research 2025;29:0192
The Histone Deacetylase Activator ITSA-1 Improves the Prognosis of Cardiac Arrest Rats by Alleviating Systemic Inflammatory Responses Following Cardiopulmonary Resuscitation.
Zhang C, Wei H, Zhang Q, Zhan H, Lu Y, Li Y, Li B, Huang W, Nian F, Liu R, Hu C, Chen J
Mediators of inflammation 2025;2025:8156593
Mediators of inflammation 2025;2025:8156593
TRIM14 Inhibition Suppresses Microglial Polarization and Pyroptosis Through the NF-κB/NLRP3 Pathway to Enhance Spinal Cord Injury Repair.
Lin X, Xia Y, Yang X, Niu P, Wang H, Liu W, Huang J, Lin F
Mediators of inflammation 2025;2025:5053685
Mediators of inflammation 2025;2025:5053685
Baicalein improves motor dysfunction and cognitive impairment while promoting remyelination in an animal model of multiple sclerosis through the antioxidant mechanism.
Wang Q, Wang Z, Li Y, Wang Q, Chen Y, Xu B, Xu H
Frontiers in pharmacology 2025;16:1659631
Frontiers in pharmacology 2025;16:1659631
Injectable ion-coordinated double-network conductive hydrogel for spinal cord injury repair.
Yu H, Liu F, Hu Y, Wan W, Liu Q, Zhou S, Zhang L, Li L, Huang F
Frontiers in bioengineering and biotechnology 2025;13:1618680
Frontiers in bioengineering and biotechnology 2025;13:1618680
Promoting spinal cord injury repair by using ZnO@MOFs nanozymes functionalized hydrogel through the ROS microenvironment regulating pathway.
Ding J, Gao B, Sang Z, Dai Z, Chen Z, Mei X
Regenerative biomaterials 2025;12:rbaf095
Regenerative biomaterials 2025;12:rbaf095
Lactobacillus acidophilus promotes cognitive function recovery via regulating microglial peroxisomal function in cerebral ischemia.
Huang Y, Zhang X, Yu C, Liu Y, Kang H, Liu Y, Ni Y, Xia Y, Jiang Z, Chen J, Zhao K, Han L, Zou X, Wang J, Lei T, Gan C, Zhang H
Cell host & microbe 2025 Sep 10;33(9):1484-1501.e12
Cell host & microbe 2025 Sep 10;33(9):1484-1501.e12
Transcription factor RUNX2 participates in astrocyte-mediated neuropathic pain via transcriptional activation of Ccl2.
Shen W, Song S, Zhao X, Li D, Liu J, Yue S
Biochemical and biophysical research communications 2025 Sep 1;777:152263
Biochemical and biophysical research communications 2025 Sep 1;777:152263
PGC-1α Expands Neural Precursor Pool and Facilitates Cognitive Recovery Within AD Hippocampus Through the Regulation of Mitochondrial Dynamics.
Wang YX, Wang YJ, Pan W, Xu LF, Wang JQ, Wang H, Qian X, Zou CZ, Zhu X, Wang J
Molecular neurobiology 2025 Oct;62(10):13534-13556
Molecular neurobiology 2025 Oct;62(10):13534-13556
Deletion of ZNRF2 Exacerbates MPTP-Induced Parkinson's Disease by Activating mTOR-Mediated Neuroinflammatory Pathways.
Zhang F, Xu J, Yuan Q, Xie Y, Zhang L, Zhang J, Xu Z, Liu M
Molecular neurobiology 2025 Oct;62(10):12394-12412
Molecular neurobiology 2025 Oct;62(10):12394-12412
USP47 Regulates Excitatory Synaptic Plasticity and Modulates Seizures in Murine Models by Blocking Ubiquitinated AMPAR Degradation.
Yang J, Zhang H, Wang Y, Luo Y, Zheng W, Liu Y, Jiang Q, Deng J, Liu Q, Zhang P, Huang H, Yu C, Xu Z, Chen Y
Neuroscience bulletin 2025 Oct;41(10):1805-1823
Neuroscience bulletin 2025 Oct;41(10):1805-1823
ILF3 downregulation by circMETTL9: Effect on traumatic brain injury-induced neuroinflammation.
Sun L, Huang H, Hu Y, Guan Y, Zhu J, Xiao C, Zhang ZJ, Liu S
Experimental neurology 2025 Oct 6;395:115490
Experimental neurology 2025 Oct 6;395:115490
Ptbp1 knockdown induces conversion of rat spinal cord astrocytes into neuron like cells.
Hu X, Han S, Li Z, Li Y, Gao J
Scientific reports 2025 Oct 14;15(1):35928
Scientific reports 2025 Oct 14;15(1):35928
Intraventricular Creatine Treatment Attenuates Alzheimer's Disease-Related Neuropathological Changes and Memory Impairment via Inhibiting STAT1 Phosphorylation.
Shao X, Sun J, Wang X, Yin XS, Chen Z, Xu Y, Wang T, Yuan B, Qiu W, Liu F, Chen Y, Ma C
ACS chemical neuroscience 2025 Oct 1;16(19):3790-3800
ACS chemical neuroscience 2025 Oct 1;16(19):3790-3800
DP1 Receptor Blockade Attenuates Microglial Senescence and Cognitive Decline Caused by PTGDS in Exosomes From Aged Brains.
Liu Y, Liao P, Yan B, Li D, Zhang S, Zhang W, Jia Z, Zhang Z, Gao H, Liu Q, Chen F, Lei P, Yin Z
Aging cell 2025 Nov;24(11):e70228
Aging cell 2025 Nov;24(11):e70228
SPP1 expression after spinal cord compression injury and its effects on glial cell activation.
Lei L, Wang X, Zhao J
Neurochemistry international 2025 Nov;190:106063
Neurochemistry international 2025 Nov;190:106063
Chronic ethanol exposure induces hippocampal neuroinflammation and neuronal damage via the astrocytic RUNX1/TOLLIP/TLR3 pathway.
Shen H, Zhang Q, Lv Q, Liu H, Wang C, Meng F, Guo Y, Pei J, Yu C, Tie J, Chen X, Zhang C, Yu H, Wang X
Brain, behavior, and immunity 2025 Nov;130:106081
Brain, behavior, and immunity 2025 Nov;130:106081
Parylation dependent nuclear export of HMGB1 via exportin 1 contributes to morphine tolerance.
Liang YP, Zhang DY, Le DS, Liu L, Yang F, Sun SY, Lai GR, Zhang C, Zhao ML, Liao PS, Liu T, Wang B
Brain, behavior, and immunity 2025 Nov;130:106070
Brain, behavior, and immunity 2025 Nov;130:106070
Microglial activation drives neuronal dysregulation in alcohol-induced seizure susceptibility.
Zhang S, Zhou Y, Ren Y, Shang J, Jiang A, Hong Y, Hong S, Wang C, Wang W, Chen J
Scientific reports 2025 Nov 3;15(1):38389
Scientific reports 2025 Nov 3;15(1):38389
Parthenolide Exerts Protection against Hypoxic-Ischemic Brain Damage in Neonatal Rats by Inhibiting Perk-Mediated Endoplasmic Reticulum Stress.
Mao N, Zheng Y, Yuan J, Feng X, Ren Y, Wang X, Tao X, Wang X, Fang M, Lin Z
Molecular neurobiology 2025 Nov 29;63(1):210
Molecular neurobiology 2025 Nov 29;63(1):210
Isoliquiritigenin ameliorates Parkinson's disease via gut microbiota remodeling: potential mediating role of Parabacteroides distasonis.
Li M, Zhang X, Lu J, Xiang J, Wu J, Zheng M, Yang S, He L, Shao X
Journal of translational medicine 2025 Nov 28;23(1):1363
Journal of translational medicine 2025 Nov 28;23(1):1363
Neutralizing XCL1 Attenuates Brain Injury and Reduces Lymphocyte and Dendritic Cell Recruitment Following Intracerebral Hemorrhage in Mice.
Shi J, Chen S, Wang J, Rastegar-Kashkooli Y, Fu P, Huang M, Zhang J, Wang J, Jiang C
Molecular neurobiology 2025 Nov 19;63(1):70
Molecular neurobiology 2025 Nov 19;63(1):70
Trigeminal root demyelination is sufficient to induce trigeminal neuralgia-like facial pain in adult rodents.
Wang ZY, Ding YQ, Wen JM, Zheng BW, Zhang K, Qi JG
The journal of headache and pain 2025 Nov 19;26(1):264
The journal of headache and pain 2025 Nov 19;26(1):264
MOF-Engineered Platelet-Mimicking Nanocarrier-Encapsulated Cascade Enzymes for ROS Scavenging and Anti-Inflammation in Cerebral Ischemia-Reperfusion Injury.
Li H, Xie X, Zhang Y, Han X, Shi T, Li J, Chen W, Wei Q, Pan H, Xu S, Chen Q, Yin L, Qin C
Pharmaceutics 2025 Nov 16;17(11)
Pharmaceutics 2025 Nov 16;17(11)
GRP78 alleviates secondary brain injury by regulating phenotype polarization in astrocytes via JAK2-STAT3 pathway after intracerebral hemorrhage.
Yang J, Duan C, Song Y, Zhu X, Shen J, Ji Q
International immunopharmacology 2025 Nov 14;165:115466
International immunopharmacology 2025 Nov 14;165:115466
Nose-to-Brain Delivery of Circular RNA SCMH1-Loaded Lipid Nanoparticles for Ischemic Stroke Therapy.
Jia Y, Xu L, Leng S, Sun Y, Huang X, Wang Y, Ren H, Li G, Bai Y, Zhang Z, Han B, Shen L, Ju M, Chen L, Yao H
Advanced materials (Deerfield Beach, Fla.) 2025 May;37(19):e2500598
Advanced materials (Deerfield Beach, Fla.) 2025 May;37(19):e2500598
Liquid-liquid phase separation of RBM33 facilitates hippocampus aging by inducing microglial senescence by activating CDKN1A.
Yang X, Wei L, Zhong S, Wang Q, Zhang Y, Zhang Y, Yu A
International journal of biological macromolecules 2025 May;310(Pt 2):142986
International journal of biological macromolecules 2025 May;310(Pt 2):142986
Hydromethylthionine sustains truncated tau-dependent inflammation-lowering effects in mouse brain.
Santos RX, Lee SH, Lofthouse R, Melis V, Robinson L, Leith M, Dreesen E, Armstrong P, Vorley T, Goatman EA, Hull C, Riedel G, Wischik CM, Harrington CR
The FEBS journal 2025 May;292(10):2602-2623
The FEBS journal 2025 May;292(10):2602-2623
PARP14 inhibits microglial activation via NNT to alleviate depressive-like behaviors in mice.
Yu X, Yang T, Wu D, Xu C, Li Z, Sun A, Gao S, Li H, Fan Z, Huang R
Brain, behavior, and immunity 2025 May;126:235-246
Brain, behavior, and immunity 2025 May;126:235-246
Loading tea polyphenols enhances the repair of human umbilical cord mesenchymal stem cell sheet after spinal cord injury.
Zhao Y, Ye C, Wang H, Chen C, Lu Y, Yang C, Xu T, Zhou Y, Wu Z, Song X, Zhu Z, Yang Z, Chen X
Stem cell research & therapy 2025 May 28;16(1):264
Stem cell research & therapy 2025 May 28;16(1):264
Complement C4 exacerbates astrocyte-mediated neuroinflammation and promotes α-synuclein pathology in Parkinson's disease.
Zou W, Kou L, Wang Y, Jin Z, Xiong N, Wang T, Xia Y
NPJ Parkinson's disease 2025 May 28;11(1):141
NPJ Parkinson's disease 2025 May 28;11(1):141
Neuroprotective potential of tranilast in streptozotocin-induced sporadic Alzheimer's disease model targeting TXNIP-NLRP3 inflammasome pathway.
Padhy DS, Vesmaker K, Banerjee S
International immunopharmacology 2025 May 27;156:114691
International immunopharmacology 2025 May 27;156:114691
Multiomics reveal biomolecular shifts and ER stress in sleep-restricted women affecting NSC functions.
Malik V, Huang X, Zhou H, Bojar R, Soni RK, Landry DW, Jelic S, Wang J
iScience 2025 May 16;28(5):112510
iScience 2025 May 16;28(5):112510
FOXG1 Improves Cognitive Function in Alzheimer's Disease by Promoting Endogenous Neurogenesis.
Pan W, Xu LF, Wang YX, Wang YJ, Wang JQ, Qian X, Zhou CZ, Wang H, Fan XH, Wang J
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 May 15;39(9):e70582
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 May 15;39(9):e70582
DANCR knockdown alleviates neuroinflammation and functional recovery after spinal cord injury via regulating the ACTN4 / STAT3 axis.
Xia B, Yu C, Liu J, Lin J, Lyu J, Wang X, Zhu L
Archives of biochemistry and biophysics 2025 Mar;765:110293
Archives of biochemistry and biophysics 2025 Mar;765:110293
Glial scarring limits recovery following decompressive surgery in rats with syringomyelia.
Cui S, Li J, Zhang C, Li Q, Jiang C, Wang X, Yu X, Li K, Feng Y, Jian F
Experimental neurology 2025 Mar;385:115113
Experimental neurology 2025 Mar;385:115113
Aerobic exercise improves clearance of amyloid-β via the glymphatic system in a mouse model of Alzheimer's Disease.
Liang S, Liu H, Wang X, Lin H, Zheng L, Zhang Y, Peng L, Huang S, Chen L
Brain research bulletin 2025 Mar;222:111263
Brain research bulletin 2025 Mar;222:111263
Vagus nerve stimulation inhibits PANoptosis and promotes neurofunctional recovery of cerebral ischemic stroke in a Sirt1-dependent manner.
Tang H, Wen J, Wang L, Yang Q, Qin T, Ren Y, Zhao Y, Li C, Li J, Cao H, Xu J, Yang Q
Neurochemistry international 2025 Mar;184:105950
Neurochemistry international 2025 Mar;184:105950
Endogenous TDP-43 mislocalization in a novel knock-in mouse model reveals DNA repair impairment, inflammation, and neuronal senescence.
Mitra J, Kodavati M, Dharmalingam P, Guerrero EN, Rao KS, Garruto RM, Hegde ML
Acta neuropathologica communications 2025 Mar 8;13(1):54
Acta neuropathologica communications 2025 Mar 8;13(1):54
Single-cell analysis reveals that GFAP(+) dedifferentiated Schwann cells promote tumor progress in PNI-positive distal cholangiocarcinoma via lactate/HMGB1 axis.
Zu Z, Zhang C, Shi J, Chen K, Tang H, Hu K, Liu E, Ji C, Feng R, Shi X, Zhai W
Cell death & disease 2025 Mar 27;16(1):215
Cell death & disease 2025 Mar 27;16(1):215
Connexin 43 is downregulated in advanced Parkinson's disease in multiple brain regions which correlates with symptoms.
Hastings N, Rahman S, Stempor PA, Wayland MT, Kuan WL, Kotter MRN
Scientific reports 2025 Mar 25;15(1):10250
Scientific reports 2025 Mar 25;15(1):10250
Intranasal Delivery of Hydrophobic AC5216 Loaded Nanoemulsion into Brain To Alleviate Chronic Unpredictable Stress-Induced Depressive-like Behaviors.
Zhang Y, Wang Y, Wang H, Bian L, Gao F, Yao H, Xie J
ACS applied materials & interfaces 2025 Mar 19;17(11):16533-16547
ACS applied materials & interfaces 2025 Mar 19;17(11):16533-16547
Intracellular metabotropic glutamate receptor 5 in spinal dorsal horn neurons contributes to pain in a mouse model of vincristine-induced neuropathic pain.
Li X, Yang H, Qian M, Liu H, Zuo S, Liu JC, Ge WH, Zhou L
Neuroscience letters 2025 Mar 15;852:138193
Neuroscience letters 2025 Mar 15;852:138193
Astrocytic pleiotrophin deficiency in the prefrontal cortex contributes to stress-induced depressive-like responses in male mice.
Chi D, Zhang K, Zhang J, He Z, Zhou H, Huang W, Liu Y, Huang J, Zeng W, Bai X, Ou C, Ouyang H
Nature communications 2025 Mar 14;16(1):2528
Nature communications 2025 Mar 14;16(1):2528
Intranasal oxytocin alleviates postsurgical pain and comorbid anxiety in mice: Participation of BK(Ca) channels in the hippocampus.
Tang YB, Tang L, Chen B, Fan MJ, Chen GJ, Ou YN, Yang F, Wu XZ
Neuropharmacology 2025 Mar 1;265:110243
Neuropharmacology 2025 Mar 1;265:110243
Ceftriaxone affects ferroptosis and alleviates glial cell activation in Parkinson's disease.
Zhi H, Wang X, Chen Y, Cai Z, Li J, Guo D
International journal of molecular medicine 2025 Jun;55(6)
International journal of molecular medicine 2025 Jun;55(6)
TNF-α mediates activation of neuronal necroptotic signaling in rat with syringomyelia.
Li J, Cui S, Li Y, Bai J, Zhang C, Li K, Jian F
Experimental neurology 2025 Jun;388:115214
Experimental neurology 2025 Jun;388:115214
Allopregnanolone relieves paclitaxel induced mechanical hypersensitivity via inhibiting spinal cord PGE(2)-EP2 mediated microglia-neuron signaling.
Guo K, Gao L, Li P, Feng S, Zhao L, Wang X
IBRO neuroscience reports 2025 Jun;18:211-221
IBRO neuroscience reports 2025 Jun;18:211-221
GPR43 regulates mitochondrial apoptosis through the cyclophilin D pathway in Alzheimer's disease.
Wang X, Wu S, Deng Z, Yan M, Wang D, Yang M, Zhong F, Song J, Chen L, Chen Y, Tian Q, Yu W, Lü Y
Molecular medicine (Cambridge, Mass.) 2025 Jun 4;31(1):219
Molecular medicine (Cambridge, Mass.) 2025 Jun 4;31(1):219
Photobiomodulation mitigates blood-brain barrier disruption in APP/PS1 mouse model of Alzheimer's disease by activating the AMPK pathway.
Ma C, Ye Y, Shi X, Li N, Mu Z, Tan T, Yin H, Dai J, Liu Y, Chen H
Alzheimer's research & therapy 2025 Jun 23;17(1):141
Alzheimer's research & therapy 2025 Jun 23;17(1):141
A Multifunctional Electrochemical Biosensor Based on Near-Infrared Light-Responsive Hydrogel for In Vivo Recording and Modulation.
Zhang C, Zheng Q, Li C, Zhu Y, Ji J, Yang G, Guo C, Wang Y, Zhu Q, Zhu W, Fu D, Ding S
Analytical chemistry 2025 Jun 17;97(23):12164-12170
Analytical chemistry 2025 Jun 17;97(23):12164-12170
CircITSN1/EIF4A3/Itsn1 axis mediates postoperative cognitive dysfunction in aged mice: A novel mechanism and therapeutic target.
Zhang C, Zhu X, Gao R, Chen H, Yan C, Liu W, Yang L, Zeng X, Yang H, Liu J, Li Q, Ma D, Zhu T, Chen C
Molecular therapy. Nucleic acids 2025 Jun 10;36(2):102555
Molecular therapy. Nucleic acids 2025 Jun 10;36(2):102555
Mesenchymal Stem Cell-Derived Mitochondrial Transfer Promotes Tip Cell Phenotype via Glutathione Metabolic Reprogramming in Stroke Mice.
Zhang Q, Huang J, Chen X, Li L, Chen L, Zhou X, Zhao X, Liu M, Zhao W, Yan J, Wang Y, Su Y, Liu Y, Xu S, Zeng W
ACS nano 2025 Jun 10;19(22):20452-20471
ACS nano 2025 Jun 10;19(22):20452-20471
Spatiotemporal transcriptomic maps of mouse intracerebral hemorrhage at single-cell resolution.
Xiang R, Wang J, Chen Z, Tao J, Peng Q, Ding R, Zhou T, Tu Z, Wang S, Yang T, Chen J, Jia Z, Li X, Zhang X, Chen S, Cheng N, Zhao M, Li J, Xue Q, Zhang H, Jiang C, Xing N, Ouyang K, Pekny A, Michalowska MM, de Pablo Y, Wilhelmsson U, Mitsios N, Liu C, Xu X, Fan X, Pekna M, Pekny M, Chen X, Liu L, Mulder J, Wang M, Wang J
Neuron 2025 Jul 9;113(13):2102-2122.e7
Neuron 2025 Jul 9;113(13):2102-2122.e7
Vagus nerve stimulation inhibits pyroptosis and improves outcome of cerebral ischemic stroke by upregulating osteopontin (SPP1) to disturb ASC oligomerization.
Wen J, Tang H, Wang L, Yang Q, Zhao Y, Ren Y, Qin T, Li X, Xu J, Jia G, Yang Q
BMC medicine 2025 Jul 7;23(1):407
BMC medicine 2025 Jul 7;23(1):407
Magnetically Driven Biomimetic Microrobot Loaded with Eleutheroside B for Targeted Delivery and Neural Repair in Spinal Cord Injury.
Niu J, Zhang F, Liu C, Xie K, Zhang Y, Zhang J, Wang X, Song C, Li B, Jiang Y, Li T, Wang Y
ACS applied materials & interfaces 2025 Jul 30;17(30):42688-42705
ACS applied materials & interfaces 2025 Jul 30;17(30):42688-42705
Exploring Core Genes Involved in Ischemic Stroke and the Therapeutic Potential of Hyperbaric Oxygen: Insights from Transcriptomic Analysis.
Bao Y, Guo X, Wang J, Kang J, Ma R, Cheng X, Ma Y, Niu Y, Zhang W, Li X
Neuromolecular medicine 2025 Jul 26;27(1):54
Neuromolecular medicine 2025 Jul 26;27(1):54
Periodontitis-induced neuroinflammation triggers IFITM3-Aβ axis to cause alzheimer's disease-like pathology and cognitive decline.
Kong L, Li J, Gao L, Zhao Y, Chen W, Wang X, Wang S, Wang F
Alzheimer's research & therapy 2025 Jul 19;17(1):166
Alzheimer's research & therapy 2025 Jul 19;17(1):166
Integrating scRNA-seq to explore offspring neurodevelopmental toxicity induced by Cyfluthrin exposure during pregnancy: A fate decision for NSCs.
Gao H, Tian X, Wu B, Geng X, Chen Y, Song Y, Yan Y, Li X, Ni W, Zhao J, Yang H
Journal of hazardous materials 2025 Jul 15;492:138205
Journal of hazardous materials 2025 Jul 15;492:138205
Selective Activation of G Protein-Coupled Estrogen Receptor 1 (GPER1) Reduces ER Stress and Pyroptosis via AMPK Signaling Pathway in Experimental Subarachnoid Hemorrhage.
Liang Y, Fu W, Tang Y, Ye H, Wang Y, Sun C, Xiang Y, Xiong W, Cui M, Chen Y, Wang T, Deng Y
Molecular neurobiology 2025 Jan;62(1):871-884
Molecular neurobiology 2025 Jan;62(1):871-884
SENP1 inhibits aerobic glycolysis in Aβ(1-42)-incubated astrocytes by promoting PUM2 deSUMOylation.
Liu Q, Jiang M, Wang Z, Meng J, Jia H, Li J, Lin J, Guo L, Gao L
Cell biology and toxicology 2025 Jan 10;41(1):28
Cell biology and toxicology 2025 Jan 10;41(1):28
Microglia-derived Galectin-9 drives amyloid-β pathology in Alzheimer's disease.
Zhang G, Peng Q, Guo X, Pan L, Xiong M, Zhang X, Dai L, Zhang Z, Xiao T, He J, Liu M, Ke W, Zhang Z
Aging cell 2025 Feb;24(2):e14396
Aging cell 2025 Feb;24(2):e14396
Endothelial AGGF1 promotes retinal angiogenesis by coordinating TNFSF12/FN14 signalling.
Cheng Y, Zhang M, Li C, Su L, Fu L, Wu S, Xu C, Sun B, Chen L
Nature communications 2025 Feb 4;16(1):1332
Nature communications 2025 Feb 4;16(1):1332
Mesenchymal stem cells overexpressing neuropeptide S promote the recovery of rats with spinal cord injury by activating the PI3K/AKT/GSK3β signaling pathway.
Yang W, Li Y, Tang Y, Tao Z, Yu M, Sun C, Ye Y, Xu B, Zhao X, Zhang Y, Lu X
Stem cell research & therapy 2025 Feb 28;16(1):100
Stem cell research & therapy 2025 Feb 28;16(1):100
Serum-tolerant polymeric complex for stem-cell transfection and neural differentiation.
Jin Y, Han G, Gao Y, Cheng H, Sun C, Ni J, Zhou J, Zhang H, Ding Y
Nature communications 2025 Feb 27;16(1):2022
Nature communications 2025 Feb 27;16(1):2022
Mogroside V ameliorates astrocyte inflammation induced by cerebral ischemia through suppressing TLR4/TRADD pathway.
Chen M, Li L, Qin Y, Teng H, Lu C, Mai R, Zhu Z, Mo J, Qi Z
International immunopharmacology 2025 Feb 20;148:114085
International immunopharmacology 2025 Feb 20;148:114085
PD-1 Attenuates Neuropathic Pain by Ameliorating NLRP3 Inflammasome-Mediated Microglia Pyroptosis.
Deng D, Ma L, Shen J, Huang L, Zhang T, Yang X, Huang S, Zhao W, Zhou Y, Fan S, Wang K, Chen X
Molecular neurobiology 2025 Dec;62(12):15478-15493
Molecular neurobiology 2025 Dec;62(12):15478-15493
Redirecting the route: Monocyte-mediated delivery of oHSV-1 across a human BBB-on-chip model.
Micheli S, Reale A, Rossetto A, Parolin C, Mammano F, Calistri A, Cimetta E
Materials today. Bio 2025 Dec;35:102458
Materials today. Bio 2025 Dec;35:102458
HCN2 promotes neurodevelopmental and synaptic function repair through the CaMKII/CREB pathway to alleviate general anesthesia-induced cognitive impairment.
Yang L, Cheng X, Ye L, Shi Y, Ye C, Wei F
Cellular signalling 2025 Dec;136:112113
Cellular signalling 2025 Dec;136:112113
VSIG2 as a novel immunosuppressive ligand interacts with Nectin-2 to regulate T cell responses.
Wang X, Hu R, Chen K, He K, Li Y, Gao J, Tian Y, Du G, Wang Z, Zhao Y, Lai L, Su M
Journal of neuroinflammation 2025 Dec 5;23(1):11
Journal of neuroinflammation 2025 Dec 5;23(1):11
Ectomesenchymal Stem Cell Transplantation Induces Microglial Polarization and Anti-inflammatory IL-10 Secretion via NF-κB and MAPK Pathways to Mitigate Brain Injury Post-cerebral Hemorrhage.
Li Y, Yang W, Tang Y, Du S, Ye Y, Xu B, Shi W, Zhao X, Lu X
Neurochemical research 2025 Dec 20;51(1):20
Neurochemical research 2025 Dec 20;51(1):20
Galectin-9 activates microglial asparagine endopeptidase and promotes α-synuclein pathology in Parkinson's disease.
Peng Q, Zhang G, Guo X, Xu X, Li Y, Pan L, Meng L, Xiong J, Li S, Zhang Z
Cell death and differentiation 2025 Dec 14;
Cell death and differentiation 2025 Dec 14;
Omega-3 Polyunsaturated Fatty Acids Prevent Sevoflurane-induced Cognitive and Fine Motor Dysfunctions in Neonatal Mice by Enhancing Phosphorylated Tau Glymphatic System Clearance Pathway.
Cao T, Jiang S, Di L, Huang P, Cao L, Wang X, Li J, Jin W, Huang L
Molecular neurobiology 2025 Dec 1;63(1):228
Molecular neurobiology 2025 Dec 1;63(1):228
Aberrant neuronal excitation promotes neuroinflammation in the primary motor cortex of ischemic stroke mice.
Li TT, Guo XF, Zhao YJ, Cheng YH, Xin DQ, Song Y, Liu DX, Wang Z
Acta pharmacologica Sinica 2025 Aug;46(8):2105-2119
Acta pharmacologica Sinica 2025 Aug;46(8):2105-2119
Fibrinogen regulates microglial function through the JAK2/STAT3 signaling pathway.
Li X, Song X, Yi F, Hou H
Cellular immunology 2025 Aug;414:104976
Cellular immunology 2025 Aug;414:104976
Edaravone ameliorates inflammation in ischemic stroke mouse by regulating the CYP1A1 pathway through gut microbiota.
Zhang Y, Jiao X, Qi X, Wang G, Ma Y
Experimental neurology 2025 Aug;390:115263
Experimental neurology 2025 Aug;390:115263
Purinergic P2X7 receptor involves in anti-retinal photodamage effects of berberine.
Ye SS, Wang JN, Zhao YF, Dai LS, Zhang JZ, Zuo YQ, Song JT
Purinergic signalling 2025 Aug;21(4):675-685
Purinergic signalling 2025 Aug;21(4):675-685
Neuroprotective effects of Yangming-Kaixin-Yizhi formula in Alzheimer's disease: dual regulation of PI3K/Akt and p38 MAPK signaling via network pharmacology and experimental approaches.
Lei J, Li J, Wu W, Xiong R, Liu Y, Tang Y
Metabolic brain disease 2025 Aug 29;40(7):254
Metabolic brain disease 2025 Aug 29;40(7):254
Deletion of SH2D5 alleviates epileptic seizures and NMDAR expression via autophagic degradation of STAT1.
Guo H, Zhang H, Zhang C, Shen Y, Jiang L, Yang M, Zhang Y, Zhang N, Zhang R, Yu R, Yang Y, Tian X
JCI insight 2025 Aug 22;10(16)
JCI insight 2025 Aug 22;10(16)
Sex-specific neurotoxicity induced by long-term bisphenol A exposure: Single-cell sequencing reveals dual mechanisms involving hippocampal gliosis and neuronal apoptosis.
Wang Z, Li C, He H, Cao Y, Liu X, Feng M, Wu T, Zhang X, Li P, Hu X, Li J, Qi C, Xiao H, Wu Q
The Science of the total environment 2025 Aug 10;989:179810
The Science of the total environment 2025 Aug 10;989:179810
USP18 is a key regulator of immune function in mouse midbrain microglia.
Lu L, Jifu C, Pei B, Gao X, Xu Z, Yin X, Xia J, Wang J
Life sciences 2025 Aug 1;374:123692
Life sciences 2025 Aug 1;374:123692
Electroacupuncture at 5/100 Hz alleviates neuropathic pain in rats by inhibiting the CCL3/CCR5 axis in the spinal cord.
Wang F, Ye Z, Yin X, Zhou C, Zhong M, Zhao G
Acupuncture in medicine : journal of the British Medical Acupuncture Society 2025 Apr;43(2):95-103
Acupuncture in medicine : journal of the British Medical Acupuncture Society 2025 Apr;43(2):95-103
Astaxanthin alleviates spinal nerve ligation-induced neuropathic pain by modulating propionic acid levels.
Li J, Dong D, Sun Y, Wang Q, Li Y, Tao X, Wang K, Zhao L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Apr;139:156448
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Apr;139:156448
Accumulation of Damaging Lipids in the Arf1-Ablated Neurons Promotes Neurodegeneration through Releasing mtDNA and Activating Inflammatory Pathways in Microglia.
Li X, Jin S, Wang D, Wu Y, Tang X, Liu Y, Yao T, Han S, Sun L, Wang Y, Hou SX
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(16):e2414260
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(16):e2414260
Photobiomodulation modulates mitochondrial energy metabolism and ameliorates neurological damage in an APP/PS1 mousmodel of Alzheimer's disease.
Chen H, Li N, Liu N, Zhu H, Ma C, Ye Y, Shi X, Luo G, Dong X, Tan T, Wei X, Yin H
Alzheimer's research & therapy 2025 Apr 5;17(1):72
Alzheimer's research & therapy 2025 Apr 5;17(1):72
Ubiquitination-mediated upregulation of glycolytic enzyme MCT4 in promoting astrocyte reactivity during neuroinflammation.
Yang L, Hu C, Chen X, Sun M, Zhang J, Feng Z, Cui T, Zhu R, Zhang X, Xiao Y, Gong Y, Yang Y, Zhang Q, Zhang Y, Yan Y
Journal of neuroinflammation 2025 Apr 30;22(1):126
Journal of neuroinflammation 2025 Apr 30;22(1):126
Neuroinflammation and hypoxia promote astrocyte phenotypic transformation and propel neurovascular dysfunction in brain arteriovenous malformation.
Tu T, Peng Z, Zhang L, Yang J, Guo K, Tang X, Ye J, Zhang F, Huang A, Yu J, Huang C, Zhang H, Wang D, Peng J, Jiang Y
Journal of neuroinflammation 2025 Apr 29;22(1):124
Journal of neuroinflammation 2025 Apr 29;22(1):124
Ticagrelor alleviates neuroinflammation after traumatic brain injury by inhibiting NLRP3 inflammasome-mediated pyroptosis.
Zhu S, Hu Z, Xu S, Tu Y
Neuroreport 2025 Apr 2;36(6):306-313
Neuroreport 2025 Apr 2;36(6):306-313
Anxiolytic effects of accelerated continuous theta burst stimulation on mice exposed to chronic restraint stress and the underlying mechanism involving gut microbiota.
Wang Y, Guo C, Zang B, Wang P, Yang C, Shi R, Kong Y, Sui A, Li S, Lin Y
Journal of affective disorders 2025 Apr 15;375:49-63
Journal of affective disorders 2025 Apr 15;375:49-63
M1 Microglia-Derived Exosomes Promote A1 Astrocyte Activation and Aggravate Ischemic Injury via circSTRN3/miR-331-5p/MAVS/NF-κB Pathway.
Li Z, Xu P, Deng Y, Duan R, Peng Q, Wang S, Xu Z, Hong Y, Zhang Y
Journal of inflammation research 2024;17:9285-9305
Journal of inflammation research 2024;17:9285-9305
Liquiritin ameliorates painful diabetic neuropathy in SD rats by inhibiting NLRP3-MMP-9-mediated reversal of aquaporin-4 polarity in the glymphatic system.
Jia SY, Yin WQ, Xu WM, Li J, Yan W, Lin JY
Frontiers in pharmacology 2024;15:1436146
Frontiers in pharmacology 2024;15:1436146
S1P/S1PR1 signaling is involved in the development of nociceptive pain.
Dong D, Yu X, Tao X, Wang Q, Zhao L
Frontiers in pharmacology 2024;15:1407347
Frontiers in pharmacology 2024;15:1407347
TAK1 inhibition mitigates intracerebral hemorrhage-induced brain injury through reduction of oxidative stress and neuronal pyroptosis via the NRF2 signaling pathway.
Zhao J, Chen C, Ge L, Jiang Z, Hu Z, Yin L
Frontiers in immunology 2024;15:1386780
Frontiers in immunology 2024;15:1386780
Astrocyte activation in hindlimb somatosensory cortex contributes to electroacupuncture analgesia in acid-induced pain.
Ye Q, Li J, Ren WJ, Zhang Y, Wang T, Rubini P, Yin HY, Illes P, Tang Y
Frontiers in neurology 2024;15:1348038
Frontiers in neurology 2024;15:1348038
Circular RNA SCMH1 suppresses KMO expression to inhibit mitophagy and promote functional recovery following stroke.
Wang Y, Bai Y, Cai Y, Zhang Y, Shen L, Xi W, Zhou Z, Xu L, Liu X, Han B, Yao H
Theranostics 2024;14(19):7292-7308
Theranostics 2024;14(19):7292-7308
Microglia and Astrocytes Responses Contribute to Alleviating Inflammatory Damage by Repetitive Transcranial Magnetic Stimulation in Rats with Traumatic Brain Injury.
Qian F, He R, Du X, Wei Y, Zhou Z, Fan J, He Y
Neurochemical research 2024 Sep;49(9):2636-2651
Neurochemical research 2024 Sep;49(9):2636-2651
The necessity of eliminating the interference of panaxatriol saponins to maximize the preventive effect of panaxadiol saponins against Parkinson's disease in rats.
Wang Y, Zhang Y, Li Y, Zhang Z, Lian XY
Journal of ginseng research 2024 Sep;48(5):464-473
Journal of ginseng research 2024 Sep;48(5):464-473
Tirzepatide shows neuroprotective effects via regulating brain glucose metabolism in APP/PS1 mice.
Yang S, Zhao X, Zhang Y, Tang Q, Li Y, Du Y, Yu P
Peptides 2024 Sep;179:171271
Peptides 2024 Sep;179:171271
Sestrin2 remedies neuroinflammatory response by inhibiting A1 astrocyte conversion via autophagy.
Pan Z, Yu X, Wang W, Shen K, Chen J, Zhang Y, Huang R
Journal of neurochemistry 2024 Sep;168(9):2640-2653
Journal of neurochemistry 2024 Sep;168(9):2640-2653
Scavenger Receptor Class B Type I Modulates Epileptic Seizures and Receptor α2δ-1 Expression.
Huang Y, Gao Y, Huang Z, Liang M, Chen Y
Neurochemical research 2024 Oct;49(10):2842-2853
Neurochemical research 2024 Oct;49(10):2842-2853
Three-Dimensional Culture of Glioblastoma Cells Using a Tissueoid Cell Culture System.
Okamoto N, Taniura N, Nakayama T, Tanaka E, Kageyama Y, Noujima M, Kushima R, Mukaisho KI
Acta histochemica et cytochemica 2024 Oct 28;57(5):149-155
Acta histochemica et cytochemica 2024 Oct 28;57(5):149-155
USP9X-mediated deubiquitination of Raptor contributes to autophagy impairment and memory deficits in P301S mice.
Zheng S, Zhu J, Wang C, Wu Y, Sun S, Guo H, Chang Y, Ma R, Li G
Cell communication and signaling : CCS 2024 Oct 24;22(1):516
Cell communication and signaling : CCS 2024 Oct 24;22(1):516
Targeted Microglial Membrane-Coated MicroRNA Nanosponge Mediates Inhibition of Glioblastoma.
Yin Y, Tian N, Deng Z, Wang J, Kuang L, Tang Y, Zhu S, Dong Z, Wang Z, Wu X, Han M, Hu X, Deng Y, Yin T, Wang Y
ACS nano 2024 Oct 22;18(42):29089-29105
ACS nano 2024 Oct 22;18(42):29089-29105
An accelerated Parkinson's disease monkey model using AAV-α-synuclein plus poly(ADP-ribose).
Liu S, Yang N, Yan Y, Wang S, Chen J, Wang Y, Gan X, Zhou J, Xie G, Wang H, Huang T, Ji W, Wang Z, Si W
Cell reports methods 2024 Oct 21;4(10):100876
Cell reports methods 2024 Oct 21;4(10):100876
Targeting exosomal double-stranded RNA-TLR3 signaling pathway attenuates morphine tolerance and hyperalgesia.
Wang B, Le DS, Liu L, Zhang XX, Yang F, Lai GR, Zhang C, Zhao ML, Shen YP, Liao PS, Liu T, Liang YP
Cell reports. Medicine 2024 Oct 15;5(10):101782
Cell reports. Medicine 2024 Oct 15;5(10):101782
Human amniotic epithelial cells improve uterine spiral artery remodeling to ameliorate preeclampsia in a rat model†.
Geng L, Qin Z, Han TL, Zhou Y, Zhong X, Zhang G, Dong X
Biology of reproduction 2024 Oct 14;111(4):906-918
Biology of reproduction 2024 Oct 14;111(4):906-918
Cynarin inhibits microglia-induced pyroptosis and neuroinflammation via Nrf2/ROS/NLRP3 axis after spinal cord injury.
Zhang B, Yu J, Bao L, Feng D, Qin Y, Fan D, Hong X, Chen Y
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2024 Nov;73(11):1981-1994
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2024 Nov;73(11):1981-1994
Shh regulates M2 microglial polarization and fibrotic scar formation after ischemic stroke.
Yang Q, Jiang P, Tang H, Wen J, Zhou L, Zhao Y, Wang L, Wang J, Yang Q
Neurochemistry international 2024 Nov;180:105862
Neurochemistry international 2024 Nov;180:105862
Hypoxanthine Produces Rapid Antidepressant Effects by Suppressing Inflammation in Serum and Hippocampus.
Wu L, Chen J, Yu Q, Lu C, Shu Y
ACS chemical neuroscience 2024 Nov 6;15(21):3970-3980
ACS chemical neuroscience 2024 Nov 6;15(21):3970-3980
Catalpol regulates apoptosis and proliferation of endothelial cell via activating HIF-1α/VEGF signaling pathway.
Ni J, Zhang Q, Jiang L, Wang H, Zhang C, Deng J
Scientific reports 2024 Nov 16;14(1):28327
Scientific reports 2024 Nov 16;14(1):28327
Whole-body vibration elicits 40 Hz cortical gamma oscillations and ameliorates age-related cognitive impairment through hippocampal astrocyte synapses in male rats.
Liu M, Li L, Chen R, Wang Q, Zeng T, Hu J, Yan C, Xiao J, Xia X
Biogerontology 2024 Nov 15;26(1):11
Biogerontology 2024 Nov 15;26(1):11
Transcriptional landscape of the interaction of human Mesenchymal Stem Cells with Glioblastoma in bioprinted co-cultures.
Oliver L, Landais Y, Gratas C, Cartron PF, Paris F, Heymann D, Vallette FM, Serandour A
Stem cell research & therapy 2024 Nov 14;15(1):424
Stem cell research & therapy 2024 Nov 14;15(1):424
A Histopathologic Correlation Study Evaluating Glymphatic Function in Brain Tumors by Multiparametric MRI.
Gao M, Liu Z, Zang H, Wu X, Yan Y, Lin H, Yuan J, Liu T, Zhou Y, Liu J
Clinical cancer research : an official journal of the American Association for Cancer Research 2024 Nov 1;30(21):4876-4886
Clinical cancer research : an official journal of the American Association for Cancer Research 2024 Nov 1;30(21):4876-4886
Development of a time-resolved immunochromatographic test strip for rapid and quantitative determination of GFAP in serum.
Wang Y, Yu Z, Ning Z, Li M, Li W, Zhong Y, Chen H, Zhang X, Tang X, Cheng X, Li L, Aigul A, Zan J
Mikrochimica acta 2024 May 13;191(6):325
Mikrochimica acta 2024 May 13;191(6):325
Let-7b-TLR7 Signaling Axis Contributes to the Anesthesia/Surgery-Induced Cognitive Impairment.
Deng L, Gao R, Chen H, Jiao B, Zhang C, Wei L, Yan C, Ye-Lehmann S, Zhu T, Chen C
Molecular neurobiology 2024 Mar;61(3):1818-1832
Molecular neurobiology 2024 Mar;61(3):1818-1832
Inhibition of aquaporin-4 and its subcellular localization attenuates below-level central neuropathic pain by regulating astrocyte activation in a rat spinal cord injury model.
Song Y, Xue T, Guo S, Yu Z, Yun C, Zhao J, Song Z, Liu Z
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2024 Mar;21(2):e00306
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2024 Mar;21(2):e00306
Inhibition of OGFOD1 by FG4592 confers neuroprotection by activating unfolded protein response and autophagy after ischemic stroke.
Xie J, Zhang Y, Li B, Xi W, Wang Y, Li L, Liu C, Shen L, Han B, Kong Y, Yao H, Zhang Z
Journal of translational medicine 2024 Mar 7;22(1):248
Journal of translational medicine 2024 Mar 7;22(1):248
The Effect of Reduced Fibrinogen on Cerebrovascular Permeability during Traumatic Brain Injury in Fibrinogen Gene Heterozygous Knockout Mice.
Sulimai N, Brown J, Lominadze D
Biomolecules 2024 Mar 22;14(4)
Biomolecules 2024 Mar 22;14(4)
Endogenous TDP-43 mislocalization in a novel knock-in mouse model reveals DNA repair impairment, inflammation, and neuronal senescence.
Mitra J, Dharmalingam P, Kodavati M, Guerrero EN, Rao KS, Garruto RM, Hegde ML
Research square 2024 Mar 20;
Research square 2024 Mar 20;
Down-regulating nuclear factor of activated T cells 1 alleviates cognitive deficits in a mouse model of sepsis-associated encephalopathy, possibly by stimulating hippocampal neurogenesis.
Guo Y, Feng Y, Jiang F, Hu L, Shan T, Li H, Liao H, Bao H, Shi H, Si Y
Brain research 2024 Mar 1;1826:148731
Brain research 2024 Mar 1;1826:148731
Enhancing stem cell therapy efficacy with functional lignin modified cerium-iron nanozyme through magnetic resonance imaging tracking and apoptosis protection in inflammatory environment.
Huang H, Zhang L, Yew PYM, Sugiarto S, Zhou R, Kai D, Wang Z
International journal of biological macromolecules 2024 Jun;271(Pt 1):132349
International journal of biological macromolecules 2024 Jun;271(Pt 1):132349
Culture of cerebrospinal fluid-contacting neurons from neonatal mouse spinal cord.
Cao L, Zhang HQ, He YQ, An PJ, Yang LL, Tan W, Liu G, Wang CQ, Dou XW, Li Q
Cell and tissue banking 2024 Jun;25(2):443-452
Cell and tissue banking 2024 Jun;25(2):443-452
MYPT1(SMKO) Mice Function as a Novel Spontaneous Age- and Hypertension-Dependent Animal Model of CSVD.
Chen J, Li CG, Yang LX, Qian Y, Zhu LW, Liu PY, Cao X, Wang Y, Zhu MS, Xu Y
Translational stroke research 2024 Jun;15(3):606-619
Translational stroke research 2024 Jun;15(3):606-619
Ginkgolide B can alleviate spinal cord glymphatic system dysfunction and provide neuroprotection in painful diabetic neuropathy rats by inhibiting matrix metalloproteinase-9.
Li J, Jia S, Song Y, Xu W, Lin J
Neuropharmacology 2024 Jun 1;250:109907
Neuropharmacology 2024 Jun 1;250:109907
CHCHD10(S59L/+) mouse model: Behavioral and neuropathological features of frontotemporal dementia.
Genin EC, di Borgo PP, Lorivel T, Hugues S, Farinelli M, Mauri-Crouzet A, Lespinasse F, Godin L, Paquis-Flucklinger V, Petit-Paitel A
Neurobiology of disease 2024 Jun 1;195:106498
Neurobiology of disease 2024 Jun 1;195:106498
Inhibition of TREM-1 alleviates neuroinflammation by modulating microglial polarization via SYK/p38MAPK signaling pathway after traumatic brain injury.
Zhao T, Zhou Y, Zhang D, Han D, Ma J, Li S, Li T, Hu S, Li Z
Brain research 2024 Jul 1;1834:148907
Brain research 2024 Jul 1;1834:148907
Small Extracellular Vesicles Derived from Altered Peptide Ligand-Loaded Dendritic Cell Act as A Therapeutic Vaccine for Spinal Cord Injury Through Eliciting CD4(+) T cell-Mediated Neuroprotective Immunity.
Wang S, Li G, Liang X, Wu Z, Chen C, Zhang F, Niu J, Li X, Yan J, Wang N, Li J, Wang Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jan;11(3):e2304648
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jan;11(3):e2304648
Pathological features and molecular signatures of early olfactory dysfunction in 3xTg-AD model mice.
Yu H, Wang F, Jia D, Bi S, Gong J, Wu JJ, Mao Y, Chen J, Chai GS
CNS neuroscience & therapeutics 2024 Feb;30(2):e14632
CNS neuroscience & therapeutics 2024 Feb;30(2):e14632
Human umbilical cord derived mesenchymal stem cells overexpressing HO-1 attenuate neural injury and enhance functional recovery by inhibiting inflammation in stroke mice.
Yang Y, Liu Q, Deng S, Shao Q, Peng L, Ling Y, Huang Y, Zheng S, Jiang Q, Nie D, Chen J
CNS neuroscience & therapeutics 2024 Feb;30(2):e14412
CNS neuroscience & therapeutics 2024 Feb;30(2):e14412
OPTN gene therapy increases autophagy and protects mitochondria in SOD1-G93A-expressing transgenic mice and cells.
Wen D, Ji Y, Li Y, Duan W, Wang Y, Li Z, Tao M, Liu Y
The FEBS journal 2024 Feb;291(4):795-813
The FEBS journal 2024 Feb;291(4):795-813
Innate immune sensing of lysosomal dysfunction drives multiple lysosomal storage disorders.
Wang A, Chen C, Mei C, Liu S, Xiang C, Fang W, Zhang F, Xu Y, Chen S, Zhang Q, Bai X, Lin A, Neculai D, Xia B, Ye C, Zou J, Liang T, Feng XH, Li X, Shen C, Xu P
Nature cell biology 2024 Feb;26(2):219-234
Nature cell biology 2024 Feb;26(2):219-234
RNF220-mediated K63-linked polyubiquitination stabilizes Olig proteins during oligodendroglial development and myelination.
Li Y, Wan LP, Song NN, Ding YQ, Zhao S, Niu J, Mao B, Sheng N, Ma P
Science advances 2024 Feb 9;10(6):eadk3931
Science advances 2024 Feb 9;10(6):eadk3931
Berberine modulates microglial polarization by activating TYROBP in Alzheimer's disease.
Yang Y, Wu J, Jia L, Feng S, Qi Z, Yu H, Wu Y, Wang S
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156237
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156237
Avicularin inhibits ferroptosis and improves cognitive impairments in Alzheimer's disease by modulating the NOX4/Nrf2 axis.
Li Z, Lu Y, Zhen Y, Jin W, Ma X, Yuan Z, Liu B, Zhou XL, Zhang L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156209
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156209
Ku70 silencing aggravates oxygen-glucose deprivation/reperfusion-induced injury by activation of the p53 apoptotic pathway in rat cortical astrocytes.
Xie X, Liu J
Histochemistry and cell biology 2024 Dec 23;163(1):20
Histochemistry and cell biology 2024 Dec 23;163(1):20
The Phenotype Changes of Astrocyte During Different Ischemia Conditions.
Meng F, Cui J, Wang P, Wang J, Sun J, Li L
Brain sciences 2024 Dec 14;14(12)
Brain sciences 2024 Dec 14;14(12)
β-hydroxybutyrate alleviates neurological deficits by restoring glymphatic and inflammation after subarachnoid hemorrhage in mice.
Tan X, Li X, Li R, Meng W, Xie Z, Li J, Pang Y, Huang G, Li L, Li H
Experimental neurology 2024 Aug;378:114819
Experimental neurology 2024 Aug;378:114819
Effects of nanoplastic exposure during pregnancy and lactation on neurodevelopment of rat offspring.
Tian L, Zhang Y, Chen J, Liu X, Nie H, Li K, Liu H, Lai W, Shi Y, Xi Z, Lin B
Journal of hazardous materials 2024 Aug 5;474:134800
Journal of hazardous materials 2024 Aug 5;474:134800
GDI2 deletion alleviates neurodegeneration and memory loss in the 5xFAD mice model of Alzheimer's disease.
Wang M, He X, Li J, Han D, You P, Yu H, Wang L, Su B
Biochimica et biophysica acta. Molecular basis of disease 2024 Apr;1870(4):167093
Biochimica et biophysica acta. Molecular basis of disease 2024 Apr;1870(4):167093
Engagement of N(6)-methyladenisine methylation of Gng4 mRNA in astrocyte dysfunction regulated by CircHECW2.
Bai Y, Chang D, Ren H, Ju M, Wang Y, Chen B, Li H, Liu X, Li D, Huo X, Guo X, Tong M, Tan Y, Yao H, Han B
Acta pharmaceutica Sinica. B 2024 Apr;14(4):1644-1660
Acta pharmaceutica Sinica. B 2024 Apr;14(4):1644-1660
Miniaturized Implantable Fluorescence Probes Integrated with Metal-Organic Frameworks for Deep Brain Dopamine Sensing.
Ling W, Shang X, Yu C, Li C, Xu K, Feng L, Wei Y, Tang T, Huang X
ACS nano 2024 Apr 16;18(15):10596-10608
ACS nano 2024 Apr 16;18(15):10596-10608
Neuron-targeted liposomal coenzyme Q10 attenuates neuronal ferroptosis after subarachnoid hemorrhage by activating the ferroptosis suppressor protein 1/coenzyme Q10 system.
Peng Z, Ding YN, Yang ZM, Li XJ, Zhuang Z, Lu Y, Tang QS, Hang CH, Li W
Acta biomaterialia 2024 Apr 15;179:325-339
Acta biomaterialia 2024 Apr 15;179:325-339
A mosquito mouthpart-like bionic neural probe.
Zhou Y, Yang H, Wang X, Yang H, Sun K, Zhou Z, Sun L, Zhao J, Tao TH, Wei X
Microsystems & nanoengineering 2023;9:88
Microsystems & nanoengineering 2023;9:88
Peroxiredoxin 2 Is a Potential Objective Indicator for Severity and the Clinical Status of Subarachnoid Hemorrhage Patients.
Peng Z, Pang C, Li XJ, Zhang HS, Zhang JT, Zhu Q, Xu HJ, Gao YY, Zhuang Z, Li W, Zhang QR, Lu Y, Hang CH
Disease markers 2023;2023:5781180
Disease markers 2023;2023:5781180
Levomilnacipran ameliorates lipopolysaccharide-induced depression-like behaviors and suppressed the TLR4/Ras signaling pathway.
Li S, Zhu Z, Lan T, Wu Y, Li Y, Wang C, Jian W, Yu SY
International immunopharmacology 2023 Sep;122:110595
International immunopharmacology 2023 Sep;122:110595
Alleviating symptoms of neurodegenerative disorders by astrocyte-specific overexpression of TMEM164 in mice.
Zhang L, Jia Z, Wu Q, Bai T, Wang B, Hu X, Li T, Liu X, Fu J, Chen Y, Ding X, Liu Z, Xu Z, Zhou H
Nature metabolism 2023 Oct;5(10):1787-1802
Nature metabolism 2023 Oct;5(10):1787-1802
Clemastine fumarate attenuates tauopathy and meliorates cognition in hTau mice via autophagy enhancement.
Zhu J, Jiang X, Chang Y, Wu Y, Sun S, Wang C, Zheng S, Wang M, Yao Y, Li G, Ma R
International immunopharmacology 2023 Oct;123:110649
International immunopharmacology 2023 Oct;123:110649
Enrofloxacin hydrochloride toxicological effects on crucian carp reflected by serological changes and neurotoxicity.
Wan G, Huang J, Wang R, Liu H, Wei L, Liang X, Li F, Wang Z, Gu X, Ruan J
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 2023 Nov;273:109737
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 2023 Nov;273:109737
ChemR23 activation attenuates cognitive impairment in chronic cerebral hypoperfusion by inhibiting NLRP3 inflammasome-induced neuronal pyroptosis.
Zhang Y, Zhang J, Zhao Y, Zhang Y, Liu L, Xu X, Wang X, Fu J
Cell death & disease 2023 Nov 6;14(11):721
Cell death & disease 2023 Nov 6;14(11):721
Losartan attenuates acetic acid enema-induced visceral hypersensitivity by inhibiting the ACE1/Ang II/AT1 receptor axis in enteric glial cells.
Sun Y, Liu X, Wang L, Li L, Quan X, Shi H, Wang T, Mei L, Chen Y, Zhang Y, Li J, Meng R, Wang J, Dai F
European journal of pharmacology 2023 May 5;946:175650
European journal of pharmacology 2023 May 5;946:175650
ARL6IP1 mediates small-molecule-induced alleviation of Alzheimer pathology through FXR1-dependent BACE1 translation initiation.
Zhou GF, Tang J, Ma YL, Fu X, Liu JY, Yang RZ, Zhang HS, Cai XH, Wang JW, Xie XY, Song L, Luo B, Chen J, Chen L, Deng XJ, Chen GJ
Proceedings of the National Academy of Sciences of the United States of America 2023 May 30;120(22):e2220148120
Proceedings of the National Academy of Sciences of the United States of America 2023 May 30;120(22):e2220148120
Thioredoxin 1 overexpression attenuated diabetes-induced endoplasmic reticulum stress in Müller cells via apoptosis signal-regulating kinase 1.
Yu X, Teng Q, Bao K, Chudhary M, Qi H, Zhou W, Che H, Liu J, Ren X, Kong L
Journal of cellular biochemistry 2023 Mar;124(3):421-433
Journal of cellular biochemistry 2023 Mar;124(3):421-433
Mechanistic Insights into the Role of OPN in Mediating Brain Damage via Triggering Lysosomal Damage in Microglia/Macrophage.
Gai C, Zhao Y, Xin D, Li T, Cheng Y, Jiang Z, Song Y, Liu D, Wang Z
Cells 2023 Mar 9;12(6)
Cells 2023 Mar 9;12(6)
Anti-CHAC1 exosomes for nose-to-brain delivery of miR-760-3p in cerebral ischemia/reperfusion injury mice inhibiting neuron ferroptosis.
Wang Y, Niu H, Li L, Han J, Liu Z, Chu M, Sha X, Zhao J
Journal of nanobiotechnology 2023 Mar 27;21(1):109
Journal of nanobiotechnology 2023 Mar 27;21(1):109
The ZSWIM8 ubiquitin ligase regulates neurodevelopment by guarding the protein quality of intrinsically disordered Dab1.
Wang G, Lei J, Wang Y, Yu J, He Y, Zhao W, Hu Z, Xu Z, Jin Y, Gu Y, Guo X, Yang B, Gao Z, Wang Z
Cerebral cortex (New York, N.Y. : 1991) 2023 Mar 21;33(7):3866-3881
Cerebral cortex (New York, N.Y. : 1991) 2023 Mar 21;33(7):3866-3881
Neuronal loss of NCLX-dependent mitochondrial calcium efflux mediates age-associated cognitive decline.
Jadiya P, Cohen HM, Kolmetzky DW, Kadam AA, Tomar D, Elrod JW
iScience 2023 Mar 17;26(3):106296
iScience 2023 Mar 17;26(3):106296
Syntaxin 7 modulates seizure activity in epilepsy.
Wu J, Zhang H, Yang L, Chen Y, Li J, Yang M, Zhang X, He C, Wang X, Xu X
Neurobiology of disease 2023 Jun 1;181:106118
Neurobiology of disease 2023 Jun 1;181:106118
Enhanced BPGM/2,3-DPG pathway activity suppresses glycolysis in hypoxic astrocytes via FIH-1 and TET2.
E G, Sun B, Liu B, Xu G, He S, Wang Y, Feng L, Wei H, Zhang J, Chen J, Gao Y, Zhang E
Brain research bulletin 2023 Jan;192:36-46
Brain research bulletin 2023 Jan;192:36-46
Neurogranin as an important regulator in swimming training to improve the spatial memory dysfunction of mice with chronic cerebral hypoperfusion.
Lin H, Zhang J, Dai Y, Liu H, He X, Chen L, Tao J, Li C, Liu W
Journal of sport and health science 2023 Jan;12(1):116-129
Journal of sport and health science 2023 Jan;12(1):116-129
Taxifolin attenuates neuroinflammation and microglial pyroptosis via the PI3K/Akt signaling pathway after spinal cord injury.
Hu Z, Xuan L, Wu T, Jiang N, Liu X, Chang J, Wang T, Han N, Tian X
International immunopharmacology 2023 Jan;114:109616
International immunopharmacology 2023 Jan;114:109616
3D Gelatin Microsphere Scaffolds Promote Functional Recovery after Spinal Cord Hemisection in Rats.
Ke H, Yang H, Zhao Y, Li T, Xin D, Gai C, Jiang Z, Wang Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Jan;10(3):e2204528
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Jan;10(3):e2204528
Transcription factor ETS proto-oncogene 1 contributes to neuropathic pain by regulating histone deacetylase 1 in primary afferent neurons.
Zheng HL, Sun SY, Jin T, Zhang M, Zeng Y, Liu Q, Yang K, Wei R, Pan Z, Lin F
Molecular pain 2023 Jan-Dec;19:17448069231152125
Molecular pain 2023 Jan-Dec;19:17448069231152125
Golgi damage caused by dysfunction of PiT-2 in primary familial brain calcification.
Sun H, Wang Z, Zhang Q, Chen N, Tang M, Yang Z, Xu Y, Kang J, Wang Y
Biochemical and biophysical research communications 2023 Jan 29;642:167-174
Biochemical and biophysical research communications 2023 Jan 29;642:167-174
Negative regulation of TREM2-mediated C9orf72 poly-GA clearance by the NLRP3 inflammasome.
Shu X, Wei C, Tu WY, Zhong K, Qi S, Wang A, Bai L, Zhang SX, Luo B, Xu ZZ, Zhang K, Shen C
Cell reports 2023 Feb 28;42(2):112133
Cell reports 2023 Feb 28;42(2):112133
Development of Brain-Derived Bioscaffolds for Neural Progenitor Cell Culture.
Terek JC, Hebb MO, Flynn LE
ACS pharmacology & translational science 2023 Feb 10;6(2):320-333
ACS pharmacology & translational science 2023 Feb 10;6(2):320-333
Neurotoxic A1 astrocytes promote neuronal ferroptosis via CXCL10/CXCR3 axis in epilepsy.
Liang P, Zhang X, Zhang Y, Wu Y, Song Y, Wang X, Chen T, Liu W, Peng B, Yin J, He F, Fan Y, Han S, He X
Free radical biology & medicine 2023 Feb 1;195:329-342
Free radical biology & medicine 2023 Feb 1;195:329-342
Extracellular RNAs-TLR3 signaling contributes to cognitive impairment after chronic neuropathic pain in mice.
Zhang X, Gao R, Zhang C, Teng Y, Chen H, Li Q, Liu C, Wu J, Wei L, Deng L, Wu L, Ye-Lehmann S, Mao X, Liu J, Zhu T, Chen C
Signal transduction and targeted therapy 2023 Aug 7;8(1):292
Signal transduction and targeted therapy 2023 Aug 7;8(1):292
Senile plaques in Alzheimer's disease arise from Aβ- and Cathepsin D-enriched mixtures leaking out during intravascular haemolysis and microaneurysm rupture.
Fu H, Li J, Du P, Jin W, Gao G, Cui D
FEBS letters 2023 Apr;597(7):1007-1040
FEBS letters 2023 Apr;597(7):1007-1040
Electroacupuncture-Regulated miR-34a-3p/PDCD6 Axis Promotes Post-Spinal Cord Injury Recovery in Both In Vitro and In Vivo Settings.
Ma L, Ma L, Yang Y, Chen T, Wang L, Deng Q
Journal of immunology research 2022;2022:9329494
Journal of immunology research 2022;2022:9329494
Dexmedetomidine Can Enhance PINK1/Parkin-Mediated Mitophagy in MPTP-Induced PD Mice Model by Activating AMPK.
Chen C, Chen Y, Liu T, Song D, Ma D, Cheng O
Oxidative medicine and cellular longevity 2022;2022:7511393
Oxidative medicine and cellular longevity 2022;2022:7511393
Downregulation of m6A Methyltransferase in the Hippocampus of Tyrobp (-/-) Mice and Implications for Learning and Memory Deficits.
Lv Z, Xu T, Li R, Zheng D, Li Y, Li W, Yang Y, Hao Y
Frontiers in neuroscience 2022;16:739201
Frontiers in neuroscience 2022;16:739201
Galectin-9/Tim-3 pathway mediates dopaminergic neurodegeneration in MPTP-induced mouse model of Parkinson's disease.
Peng Q, Zhang G, Guo X, Dai L, Xiong M, Zhang Z, Chen L, Zhang Z
Frontiers in molecular neuroscience 2022;15:1046992
Frontiers in molecular neuroscience 2022;15:1046992
Nanoformulated Bumetanide Ameliorates Social Deficiency in BTBR Mice Model of Autism Spectrum Disorder.
Lv H, Gu X, Shan X, Zhu T, Ma B, Zhang HT, Bambini-Junior V, Zhang T, Li WG, Gao X, Li F
Frontiers in immunology 2022;13:870577
Frontiers in immunology 2022;13:870577
AQP2 Promotes Astrocyte Activation by Modulating the TLR4/NFκB-p65 Pathway Following Intracerebral Hemorrhage.
Deng S, Chen X, Lei Q, Lu W
Frontiers in immunology 2022;13:847360
Frontiers in immunology 2022;13:847360
Combined cell grafting and VPA administration facilitates neural repair through axonal regeneration and synaptogenesis in traumatic brain injury.
Liu S, Tian H, Niu Y, Yu C, Xie L, Jin Z, Niu W, Ren J, Fu L, Yao Z
Acta biochimica et biophysica Sinica 2022 Sep 25;54(9):1289-1300
Acta biochimica et biophysica Sinica 2022 Sep 25;54(9):1289-1300
Exogenous TIPE2 Inhibit TAK1 to Improve Inflammation and Neuropathic Pain Induced by Sciatic Nerve Injury Through Inactivating NF-κB and JNK.
Sun X, Li X, Zhou Y, Wang Y, Liu X
Neurochemical research 2022 Oct;47(10):3167-3177
Neurochemical research 2022 Oct;47(10):3167-3177
Blood-brain barrier permeability to enrofloxacin in Pengze crucian carp (Carassius auratus var. Pengze).
Zhang F, Wang R, Huang J, Zhang H, Wang L, Zhong Z, Ruan J, Liu H
Veterinary medicine and science 2022 Nov;8(6):2404-2410
Veterinary medicine and science 2022 Nov;8(6):2404-2410
FOXG1 Contributes Adult Hippocampal Neurogenesis in Mice.
Wang J, Zhai HR, Ma SF, Shi HZ, Zhang WJ, Yun Q, Liu WJ, Liu ZZ, Zhang WN
International journal of molecular sciences 2022 Nov 29;23(23)
International journal of molecular sciences 2022 Nov 29;23(23)
Dexmedetomidine alleviates pain in MPTP-treated mice by activating the AMPK/mTOR/NF-κB pathways in astrocytes.
Chen Y, Li Y, Li C, Zhu D, Cheng O, Cui J
Neuroscience letters 2022 Nov 20;791:136933
Neuroscience letters 2022 Nov 20;791:136933
The effect of prolonged formalin fixation on the expression of proteins in human brain tissues.
Wu X, Deng C, Su Y, Zhang C, Chen M, Tian K, Wu H, Xu S
Acta histochemica 2022 May;124(4):151879
Acta histochemica 2022 May;124(4):151879
Seizures in PPT1 Knock-In Mice Are Associated with Inflammatory Activation of Microglia.
Zhang X, Wang M, Feng B, Zhang Q, Tong J, Wang M, Lu C, Peng S
International journal of molecular sciences 2022 May 17;23(10)
International journal of molecular sciences 2022 May 17;23(10)
Repair of Spinal Cord Injury by Inhibition of PLK4 Expression Through Local Delivery of siRNA-Loaded Nanoparticles.
Gu Y, Zhang R, Jiang B, Xu X, Guan JJ, Jiang XJ, Zhou Y, Zhou YL, Chen X
Journal of molecular neuroscience : MN 2022 Mar;72(3):544-554
Journal of molecular neuroscience : MN 2022 Mar;72(3):544-554
The circadian clock protein Rev-erbα provides neuroprotection and attenuates neuroinflammation against Parkinson's disease via the microglial NLRP3 inflammasome.
Kou L, Chi X, Sun Y, Han C, Wan F, Hu J, Yin S, Wu J, Li Y, Zhou Q, Zou W, Xiong N, Huang J, Xia Y, Wang T
Journal of neuroinflammation 2022 Jun 6;19(1):133
Journal of neuroinflammation 2022 Jun 6;19(1):133
Pancreatic Stellate Cells Prolong Ex Vivo Islet Viability and Function and Improve Engraftment.
Paul PK, Das R, Drow TJ, de Souza AH, Balamurugan AN, Belt Davis D, Galipeau J
Stem cells translational medicine 2022 Jun 22;11(6):630-643
Stem cells translational medicine 2022 Jun 22;11(6):630-643
Indole-3-propionic acid alleviates ischemic brain injury in a mouse middle cerebral artery occlusion model.
Xie Y, Zou X, Han J, Zhang Z, Feng Z, Ouyang Q, Hua S, Liu Z, Li C, Cai Y, Zou Y, Tang Y, Jiang X
Experimental neurology 2022 Jul;353:114081
Experimental neurology 2022 Jul;353:114081
Sigma-1 receptor activation alleviates blood-brain barrier disruption post cerebral ischemia stroke by stimulating the GDNF-GFRα1-RET pathway.
Liu D, Yang L, Liu P, Ji X, Qi X, Wang Z, Chi T, Zou L
Experimental neurology 2022 Jan;347:113867
Experimental neurology 2022 Jan;347:113867
Extracellular vesicle-mediated delivery of circDYM alleviates CUS-induced depressive-like behaviours.
Yu X, Bai Y, Han B, Ju M, Tang T, Shen L, Li M, Yang L, Zhang Z, Hu G, Chao J, Zhang Y, Yao H
Journal of extracellular vesicles 2022 Jan;11(1):e12185
Journal of extracellular vesicles 2022 Jan;11(1):e12185
Islet amyloid polypeptide cross-seeds tau and drives the neurofibrillary pathology in Alzheimer's disease.
Zhang G, Meng L, Wang Z, Peng Q, Chen G, Xiong J, Zhang Z
Molecular neurodegeneration 2022 Jan 29;17(1):12
Molecular neurodegeneration 2022 Jan 29;17(1):12
Astrocytic VEGFA: An essential mediator in blood-brain-barrier disruption in Parkinson's disease.
Lan G, Wang P, Chan RB, Liu Z, Yu Z, Liu X, Yang Y, Zhang J
Glia 2022 Feb;70(2):337-353
Glia 2022 Feb;70(2):337-353
High, in Contrast to Low Levels of Acute Stress Induce Depressive-like Behavior by Involving Astrocytic, in Addition to Microglial P2X7 Receptors in the Rodent Hippocampus.
Zhao YF, Ren WJ, Zhang Y, He JR, Yin HY, Liao Y, Rubini P, Deussing JM, Verkhratsky A, Yuan ZQ, Illes P, Tang Y
International journal of molecular sciences 2022 Feb 8;23(3)
International journal of molecular sciences 2022 Feb 8;23(3)
Fine-tuning of mTOR signaling by the UBE4B-KLHL22 E3 ubiquitin ligase cascade in brain development.
Kong X, Shu X, Wang J, Liu D, Ni Y, Zhao W, Wang L, Gao Z, Chen J, Yang B, Guo X, Wang Z
Development (Cambridge, England) 2022 Dec 15;149(24)
Development (Cambridge, England) 2022 Dec 15;149(24)
Spatial transcriptomics shows moxibustion promotes hippocampus astrocyte and neuron interaction.
Zhang N, Shen Y, Zhu W, Li C, Liu S, Li H, Wang Y, Wang J, Zhang Q, Sun J, Xie L, Yu S, Wu Q
Life sciences 2022 Dec 1;310:121052
Life sciences 2022 Dec 1;310:121052
Fucoidan ameliorates LPS-induced neuronal cell damage and cognitive impairment in mice.
Wang Y, Wang Q, Duan L, Li X, Yang W, Huang T, Kong M, Guan F, Ma S
International journal of biological macromolecules 2022 Dec 1;222(Pt A):759-771
International journal of biological macromolecules 2022 Dec 1;222(Pt A):759-771
Cornuside Is a Potential Agent against Alzheimer's Disease via Orchestration of Reactive Astrocytes.
Shi JZ, Zheng XM, Zhou YF, Yun LY, Luo DM, Hao JJ, Liu PF, Zhang WK, Xu JK, Yan Y, Xie XM, He YY, Pang XB
Nutrients 2022 Aug 3;14(15)
Nutrients 2022 Aug 3;14(15)
Multifunctional chitin-based hollow nerve conduit for peripheral nerve regeneration and neuroma inhibition.
Yang X, Huang L, Yi X, Huang S, Duan B, Yu A
Carbohydrate polymers 2022 Aug 1;289:119443
Carbohydrate polymers 2022 Aug 1;289:119443
CUMS and dexamethasone induce depression-like phenotypes in mice by differentially altering gut microbiota and triggering macroglia activation.
Wu J, Li J, Gaurav C, Muhammad U, Chen Y, Li X, Chen J, Wang Z
General psychiatry 2021;34(6):e100529
General psychiatry 2021;34(6):e100529
Destructive Effects of Pyroptosis on Homeostasis of Neuron Survival Associated with the Dysfunctional BBB-Glymphatic System and Amyloid-Beta Accumulation after Cerebral Ischemia/Reperfusion in Rats.
Lyu Z, Chan Y, Li Q, Zhang Q, Liu K, Xiang J, Li X, Cai D, Li Y, Wang B, Yu Z
Neural plasticity 2021;2021:4504363
Neural plasticity 2021;2021:4504363
The Neural Stem Cell Properties of PKD2L1(+) Cerebrospinal Fluid-Contacting Neurons in vitro.
Wang S, He Y, Zhang H, Chen L, Cao L, Yang L, Wang C, Pan Y, Tang Q, Tan W, Dou X, Li Q
Frontiers in cellular neuroscience 2021;15:630882
Frontiers in cellular neuroscience 2021;15:630882
L-Cysteine Provides Neuroprotection of Hypoxia-Ischemia Injury in Neonatal Mice via a PI3K/Akt-Dependent Mechanism.
Li T, Li J, Li T, Zhao Y, Ke H, Wang S, Liu D, Wang Z
Drug design, development and therapy 2021;15:517-529
Drug design, development and therapy 2021;15:517-529
Quantitative Proteomics Reveals the Dynamic Pathophysiology Across Different Stages in a Rat Model of Severe Traumatic Brain Injury.
Luo W, Yang Z, Zhang W, Zhou D, Guo X, Wang S, He F, Wang Y
Frontiers in molecular neuroscience 2021;14:785938
Frontiers in molecular neuroscience 2021;14:785938
Agomelatine Prevents Amyloid Plaque Deposition, Tau Phosphorylation, and Neuroinflammation in APP/PS1 Mice.
Yang XB, Zu HB, Zhao YF, Yao K
Frontiers in aging neuroscience 2021;13:766410
Frontiers in aging neuroscience 2021;13:766410
Fascin-1 is Highly Expressed Specifically in Microglia After Spinal Cord Injury and Regulates Microglial Migration.
Yu S, Cheng L, Tian D, Li Z, Yao F, Luo Y, Liu Y, Zhu Z, Zheng M, Jing J
Frontiers in pharmacology 2021;12:729524
Frontiers in pharmacology 2021;12:729524
Reconstituting neurovascular unit with primary neural stem cells and brain microvascular endothelial cells in three-dimensional matrix.
Wang H, Yang H, Shi Y, Xiao Y, Yin Y, Jiang B, Ren H, Chen W, Xue Q, Xu X
Brain pathology (Zurich, Switzerland) 2021 Sep;31(5):e12940
Brain pathology (Zurich, Switzerland) 2021 Sep;31(5):e12940
High-speed, cortex-wide volumetric recording of neuroactivity at cellular resolution using light beads microscopy.
Demas J, Manley J, Tejera F, Barber K, Kim H, Traub FM, Chen B, Vaziri A
Nature methods 2021 Sep;18(9):1103-1111
Nature methods 2021 Sep;18(9):1103-1111
The role of cell-free DNA in fibrinolysis for intraventricular hemorrhage.
Xie F, Tan Q, Yu A, Guo P, Wang L, Zeng Z, Liang L, Xian J, Feng H, Chen Z
Journal of neurosurgery 2021 Oct 1;135(4):1105-1112
Journal of neurosurgery 2021 Oct 1;135(4):1105-1112
Wnt10a/β-catenin signalling is involved in kindlin-1-mediated astrocyte activation in a chronic construction injury rat model.
Zhao B, Pan Y, Xu H, Song X
The European journal of neuroscience 2021 Nov;54(10):7409-7421
The European journal of neuroscience 2021 Nov;54(10):7409-7421
Stanniocalcin-1 Protected Astrocytes from Hypoxic Damage Through the AMPK Pathway.
Sun B, He S, Liu B, Xu G, Guoji E, Feng L, Xu L, Chen D, Zhao W, Chen J, Gao Y, Zhang E
Neurochemical research 2021 Nov;46(11):2948-2957
Neurochemical research 2021 Nov;46(11):2948-2957
Effects of Chronic Secondhand Smoke (SHS) Exposure on Cognitive Performance and Metabolic Pathways in the Hippocampus of Wild-Type and Human Tau Mice.
Raber J, Perez R, Torres ERS, Krenik D, Boutros S, Patel E, Chlebowski AC, Torres ER, Perveen Z, Penn A, Paulsen DB, Bartlett MG, Jia E, Holden S, Hall R, Morré J, Wong C, Ho E, Choi J, Stevens JF, Noël A, Bobe G, Kisby G
Environmental health perspectives 2021 May;129(5):57009
Environmental health perspectives 2021 May;129(5):57009
Restoration of CTSD (cathepsin D) and lysosomal function in stroke is neuroprotective.
Hossain MI, Marcus JM, Lee JH, Garcia PL, Singh V, Shacka JJ, Zhang J, Gropen TI, Falany CN, Andrabi SA
Autophagy 2021 Jun;17(6):1330-1348
Autophagy 2021 Jun;17(6):1330-1348
UBQLN2-HSP70 axis reduces poly-Gly-Ala aggregates and alleviates behavioral defects in the C9ORF72 animal model.
Zhang K, Wang A, Zhong K, Qi S, Wei C, Shu X, Tu WY, Xu W, Xia C, Xiao Y, Chen A, Bai L, Zhang J, Luo B, Wang W, Shen C
Neuron 2021 Jun 16;109(12):1949-1962.e6
Neuron 2021 Jun 16;109(12):1949-1962.e6
A Multichannel Flexible Optoelectronic Fiber Device for Distributed Implantable Neurological Stimulation and Monitoring.
Yu J, Ling W, Li Y, Ma N, Wu Z, Liang R, Pan H, Liu W, Fu B, Wang K, Li C, Wang H, Peng H, Ning B, Yang J, Huang X
Small (Weinheim an der Bergstrasse, Germany) 2021 Jan;17(4):e2005925
Small (Weinheim an der Bergstrasse, Germany) 2021 Jan;17(4):e2005925
Genetic deletion of Rnd3 suppresses apoptosis through NF‑κB signaling in the brain.
Dong H, Sun Q, Zhang Y, Li Y, Yuan F, Mao S, Liu B
Oncology reports 2021 Feb;45(2):595-605
Oncology reports 2021 Feb;45(2):595-605
3-Hydroxybenzaldehyde and 4-Hydroxybenzaldehyde enhance survival of mouse astrocytes treated with Angiostrongylus cantonensis young adults excretory/secretory products.
Chen KY, Chen YJ, Cheng CJ, Jhan KY, Chiu CH, Wang LC
Biomedical journal 2021 Dec;44(6 Suppl 2):S258-S266
Biomedical journal 2021 Dec;44(6 Suppl 2):S258-S266
KAT1 triggers YTHDF2-mediated ITGB1 mRNA instability to alleviate the progression of diabetic retinopathy.
Qi Y, Yao R, Zhang W, Cui Q
Pharmacological research 2021 Aug;170:105713
Pharmacological research 2021 Aug;170:105713
Injectable Gelatin Hydrogel Suppresses Inflammation and Enhances Functional Recovery in a Mouse Model of Intracerebral Hemorrhage.
Xu J, Duan Z, Qi X, Ou Y, Guo X, Zi L, Wei Y, Liu H, Ma L, Li H, You C, Tian M
Frontiers in bioengineering and biotechnology 2020;8:785
Frontiers in bioengineering and biotechnology 2020;8:785
Effects of Ginkgo biloba on Early Decompression after Spinal Cord Injury.
Guo X, Wang X, Dong J, Lv W, Zhao S, Jin L, Guo J, Wang M, Cai C, Sun J, Zhou Y, Zhang Q, Chen X, Yang J, Ji R, Xin X, Li M, Li Y, Fan J
Evidence-based complementary and alternative medicine : eCAM 2020;2020:6958246
Evidence-based complementary and alternative medicine : eCAM 2020;2020:6958246
Nrf2 Ablation Promotes Alzheimer's Disease-Like Pathology in APP/PS1 Transgenic Mice: The Role of Neuroinflammation and Oxidative Stress.
Ren P, Chen J, Li B, Zhang M, Yang B, Guo X, Chen Z, Cheng H, Wang P, Wang S, Wang N, Zhang G, Wu X, Ma D, Guan D, Zhao R
Oxidative medicine and cellular longevity 2020;2020:3050971
Oxidative medicine and cellular longevity 2020;2020:3050971
Effects of Xiaoyaosan on Depressive-Like Behaviors in Rats With Chronic Unpredictable Mild Stress Through HPA Axis Induced Astrocytic Activities.
Song M, Zhang J, Li X, Liu Y, Wang T, Yan Z, Chen J
Frontiers in psychiatry 2020;11:545823
Frontiers in psychiatry 2020;11:545823
Autophagic degradation of PML promotes susceptibility to HSV-1 by stress-induced corticosterone.
Li W, Luo Z, Yan CY, Wang XH, He ZJ, Ouyang SH, Yan C, Liu LF, Zhou QQ, Mu HL, Gong HB, Duan WJ, Liang L, Kurihara H, Feng D, Li YF, He RR
Theranostics 2020;10(20):9032-9049
Theranostics 2020;10(20):9032-9049
Effects of seawater immersion on open traumatic brain injury in rabbit model.
Liu KL, Yu XJ, Sun TZ, Wang YC, Chen MX, Su YW, Zhang HC, Chen YM, Gao HL, Shi XL, Qi J, Li Y, Li HB, Dong WJ, He JK, Kang YM
Brain research 2020 Sep 15;1743:146903
Brain research 2020 Sep 15;1743:146903
Mesenchymal stromal cell-derived extracellular vesicles modulate microglia/macrophage polarization and protect the brain against hypoxia-ischemic injury in neonatal mice by targeting delivery of miR-21a-5p.
Xin D, Li T, Chu X, Ke H, Yu Z, Cao L, Bai X, Liu D, Wang Z
Acta biomaterialia 2020 Sep 1;113:597-613
Acta biomaterialia 2020 Sep 1;113:597-613
Annexin A7 induction of neuronal apoptosis via effect on glutamate release in a rat model of subarachnoid hemorrhage.
Lin QS, Wang WX, Lin YX, Lin ZY, Yu LH, Kang Y, Kang DZ
Journal of neurosurgery 2020 Mar 1;132(3):777-787
Journal of neurosurgery 2020 Mar 1;132(3):777-787
Bexarotene Improve Depression-Like Behaviour in Mice by Protecting Against Neuro-inflammation and Synaptic Damage.
Yuan C, Dai C, Li Z, Zheng L, Zhao M, Dong S
Neurochemical research 2020 Jul;45(7):1500-1509
Neurochemical research 2020 Jul;45(7):1500-1509
The LncRNA H19/miR-1-3p/CCL2 axis modulates lipopolysaccharide (LPS) stimulation-induced normal human astrocyte proliferation and activation.
Li P, Li Y, Dai Y, Wang B, Li L, Jiang B, Wu P, Xu J
Cytokine 2020 Jul;131:155106
Cytokine 2020 Jul;131:155106
Brain-derived neurotrophic factor and Glial cell line-derived neurotrophic factor expressions in the trigeminal root entry zone and trigeminal ganglion neurons of a trigeminal neuralgia rat model.
Luo D, Luo L, Lin R, Lin L, Lin Q
Anatomical record (Hoboken, N.J. : 2007) 2020 Dec;303(12):3014-3023
Anatomical record (Hoboken, N.J. : 2007) 2020 Dec;303(12):3014-3023
Pentraxin 3 contributes to neurogenesis after traumatic brain injury in mice.
Zhou C, Chen H, Zheng JF, Guo ZD, Huang ZJ, Wu Y, Zhong JJ, Sun XC, Cheng CJ
Neural regeneration research 2020 Dec;15(12):2318-2326
Neural regeneration research 2020 Dec;15(12):2318-2326
FSHR ablation induces depression-like behaviors.
Bi WK, Shao SS, Li ZW, Ruan YW, Luan SS, Dong ZH, Wang J, Wu SS, Guo T, Ma SZ, Gao L, Zhao JJ, He Z
Acta pharmacologica Sinica 2020 Aug;41(8):1033-1040
Acta pharmacologica Sinica 2020 Aug;41(8):1033-1040
STK24 modulates excitatory synaptic transmission in epileptic hippocampal neurons.
Yang J, Jiang Q, Yu X, Xu T, Wang Y, Deng J, Liu Y, Chen Y
CNS neuroscience & therapeutics 2020 Aug;26(8):851-861
CNS neuroscience & therapeutics 2020 Aug;26(8):851-861
L-Cysteine-Derived H(2)S Promotes Microglia M2 Polarization via Activation of the AMPK Pathway in Hypoxia-Ischemic Neonatal Mice.
Zhou X, Chu X, Xin D, Li T, Bai X, Qiu J, Yuan H, Liu D, Wang D, Wang Z
Frontiers in molecular neuroscience 2019;12:58
Frontiers in molecular neuroscience 2019;12:58
Inhibition of Nwd1 activity attenuates neuronal hyperexcitability and GluN2B phosphorylation in the hippocampus.
Yang Q, Huang Z, Luo Y, Zheng F, Hu Y, Liu H, Zhu S, He M, Xu D, Li Y, Yang M, Yang Y, Wei X, Gao X, Wang W, Ma J, Ma Y, Wang X, Wang Q
EBioMedicine 2019 Sep;47:470-483
EBioMedicine 2019 Sep;47:470-483
Interleukin-6: Its role and mechanisms in rescuing depression-like behaviors in rat models of depression.
Wang P, Feng YB, Wang L, Li Y, Fan C, Song Q, Yu SY
Brain, behavior, and immunity 2019 Nov;82:106-121
Brain, behavior, and immunity 2019 Nov;82:106-121
Silencing Huwe1 reduces apoptosis of cortical neurons exposed to oxygen-glucose deprivation and reperfusion.
He GQ, Xu WM, Liao HJ, Jiang C, Li CQ, Zhang W
Neural regeneration research 2019 Nov;14(11):1977-1985
Neural regeneration research 2019 Nov;14(11):1977-1985
Glutamate affects the CYP1B1- and CYP2U1-mediated hydroxylation of arachidonic acid metabolism via astrocytic mGlu5 receptor.
Yu X, Wu J, Hu M, Wu J, Zhu Q, Yang Z, Xie X, Feng YQ, Yue J
The international journal of biochemistry & cell biology 2019 May;110:111-121
The international journal of biochemistry & cell biology 2019 May;110:111-121
Neuroprotective effects of matrix metalloproteinases in cerebral ischemic rats by promoting activation and migration of astrocytes and microglia.
Zhang X, Zhao HH, Li D, Li HP
Brain research bulletin 2019 Mar;146:136-142
Brain research bulletin 2019 Mar;146:136-142
Dynamic cell type-specific expression of Nrf2 after traumatic brain injury in mice.
Dong W, Sun Y, Cheng H, Yang B, Wang L, Jiang Z, Li B, Wen S, Guo X, Guan D, Zhao R
The European journal of neuroscience 2019 Jul;50(2):1981-1993
The European journal of neuroscience 2019 Jul;50(2):1981-1993
Mesenchymal stem cell derived EVs mediate neuroprotection after spinal cord injury in rats via the microRNA-21-5p/FasL gene axis.
Zhou X, Chu X, Yuan H, Qiu J, Zhao C, Xin D, Li T, Ma W, Wang H, Wang Z, Wang D
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jul;115:108818
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jul;115:108818
Icariin Ameliorates Amyloid Pathologies by Maintaining Homeostasis of Autophagic Systems in Aβ(1-42)-Injected Rats.
Jiang X, Chen LL, Lan Z, Xiong F, Xu X, Yin YY, Li P, Wang P
Neurochemical research 2019 Dec;44(12):2708-2722
Neurochemical research 2019 Dec;44(12):2708-2722
COX-2 inhibition rescues depression-like behaviors via suppressing glial activation, oxidative stress and neuronal apoptosis in rats.
Song Q, Feng YB, Wang L, Shen J, Li Y, Fan C, Wang P, Yu SY
Neuropharmacology 2019 Dec 1;160:107779
Neuropharmacology 2019 Dec 1;160:107779
Extracellular RNAs-TLR3 signaling contributes to cognitive decline in a mouse model of postoperative cognitive dysfunction.
Chen C, Gao R, Li M, Wang Q, Chen H, Zhang S, Mao X, Behensky A, Zhang Z, Gan L, Li T, Liao R, Li Q, Yu H, Yang J, Zhu T, Liu J
Brain, behavior, and immunity 2019 Aug;80:439-451
Brain, behavior, and immunity 2019 Aug;80:439-451
Glial Plasticity in the Trigeminal Root Entry Zone of a Rat Trigeminal Neuralgia Animal Model.
Luo D, Lin R, Luo L, Li Q, Chen T, Qiu R, Li Y
Neurochemical research 2019 Aug;44(8):1893-1902
Neurochemical research 2019 Aug;44(8):1893-1902
Resistin-Inhibited Neural Stem Cell-Derived Astrocyte Differentiation Contributes to Permeability Destruction of the Blood-Brain Barrier.
Xiaoying L, Li T, Yu S, Jiusheng J, Jilin Z, Jiayi W, Dongxin L, Wengang F, Xinyue Z, Hao Y, Yuhua C, Deshu S
Neurochemical research 2019 Apr;44(4):905-916
Neurochemical research 2019 Apr;44(4):905-916
Methylene blue offers neuroprotection after intracerebral hemorrhage in rats through the PI3K/Akt/GSK3β signaling pathway.
Chen C, Zhou F, Zeng L, Jiang Z, Hu Z
Journal of cellular physiology 2019 Apr;234(4):5304-5318
Journal of cellular physiology 2019 Apr;234(4):5304-5318
Targeting Smox Is Neuroprotective and Ameliorates Brain Inflammation in Cerebral Ischemia/Reperfusion Rats.
Fan J, Chen M, Wang X, Tian Z, Wang J, Fan D, Zeng J, Zhang K, Dai X
Toxicological sciences : an official journal of the Society of Toxicology 2019 Apr 1;168(2):381-393
Toxicological sciences : an official journal of the Society of Toxicology 2019 Apr 1;168(2):381-393
Xanthoceraside modulates neurogenesis to ameliorate cognitive impairment in APP/PS1 transgenic mice.
Zhu L, Chi T, Zhao X, Yang L, Song S, Lu Q, Ji X, Liu P, Wang L, Zou L
The journal of physiological sciences : JPS 2018 Sep;68(5):555-565
The journal of physiological sciences : JPS 2018 Sep;68(5):555-565
Limb remote ischemic postconditioning protects integrity of the blood-brain barrier after stroke.
Li J, Hu XS, Zhou FF, Li S, Lin YS, Qi WQ, Qi CF, Zhang X
Neural regeneration research 2018 Sep;13(9):1585-1593
Neural regeneration research 2018 Sep;13(9):1585-1593
l-Cysteine suppresses hypoxia-ischemia injury in neonatal mice by reducing glial activation, promoting autophagic flux and mediating synaptic modification via H(2)S formation.
Xin D, Chu X, Bai X, Ma W, Yuan H, Qiu J, Liu C, Li T, Zhou X, Chen W, Liu D, Wang Z
Brain, behavior, and immunity 2018 Oct;73:222-234
Brain, behavior, and immunity 2018 Oct;73:222-234
GPR40 modulates epileptic seizure and NMDA receptor function.
Yang Y, Tian X, Xu D, Zheng F, Lu X, Zhang Y, Ma Y, Li Y, Xu X, Zhu B, Wang X
Science advances 2018 Oct;4(10):eaau2357
Science advances 2018 Oct;4(10):eaau2357
KPNB1 inhibition disrupts proteostasis and triggers unfolded protein response-mediated apoptosis in glioblastoma cells.
Zhu ZC, Liu JW, Li K, Zheng J, Xiong ZQ
Oncogene 2018 May;37(22):2936-2952
Oncogene 2018 May;37(22):2936-2952
CD4+ αβ T cell infiltration into the leptomeninges of lumbar dorsal roots contributes to the transition from acute to chronic mechanical allodynia after adult rat tibial nerve injuries.
Du B, Ding YQ, Xiao X, Ren HY, Su BY, Qi JG
Journal of neuroinflammation 2018 Mar 15;15(1):81
Journal of neuroinflammation 2018 Mar 15;15(1):81
Inhibition of Cdk5 rejuvenates inhibitory circuits and restores experience-dependent plasticity in adult visual cortex.
Li Y, Wang L, Zhang X, Huang M, Li S, Wang X, Chen L, Jiang B, Yang Y
Neuropharmacology 2018 Jan;128:207-220
Neuropharmacology 2018 Jan;128:207-220
RNF20 controls astrocytic differentiation through epigenetic regulation of STAT3 in the developing brain.
Liang Q, Xia W, Li W, Jiao J
Cell death and differentiation 2018 Feb;25(2):294-306
Cell death and differentiation 2018 Feb;25(2):294-306
Apolipoprotein E Exerts a Whole-Brain Protective Property by Promoting M1? Microglia Quiescence After Experimental Subarachnoid Hemorrhage in Mice.
Pang J, Peng J, Matei N, Yang P, Kuai L, Wu Y, Chen L, Vitek MP, Li F, Sun X, Zhang JH, Jiang Y
Translational stroke research 2018 Dec;9(6):654-668
Translational stroke research 2018 Dec;9(6):654-668
Hippocampal CA1 βCaMKII mediates neuroinflammatory responses via COX-2/PGE2 signaling pathways in depression.
Song Q, Fan C, Wang P, Li Y, Yang M, Yu SY
Journal of neuroinflammation 2018 Dec 8;15(1):338
Journal of neuroinflammation 2018 Dec 8;15(1):338
HIF-1α is Critical for the Activation of Notch Signaling in Neurogenesis During Acute Epilepsy.
Li Y, Wu L, Yu M, Yang F, Wu B, Lu S, Tu M, Xu H
Neuroscience 2018 Dec 1;394:206-219
Neuroscience 2018 Dec 1;394:206-219
Transcriptome-Wide Identification of Differentially Expressed Genes and Long Non-coding RNAs in Aluminum-Treated Rat Hippocampus.
Xu Y, Zhang H, Pan B, Zhang S, Wang S, Niu Q
Neurotoxicity research 2018 Aug;34(2):220-232
Neurotoxicity research 2018 Aug;34(2):220-232
The BAF45D Protein Is Preferentially Expressed in Adult Neurogenic Zones and in Neurons and May Be Required for Retinoid Acid Induced PAX6 Expression.
Liu C, Sun R, Huang J, Zhang D, Huang D, Qi W, Wang S, Xie F, Shen Y, Shen C
Frontiers in neuroanatomy 2017;11:94
Frontiers in neuroanatomy 2017;11:94
Activation inhibitors of nuclear factor kappa B protect neurons against the NMDA-induced damage in the rat retina.
Sakamoto K, Okuwaki T, Ushikubo H, Mori A, Nakahara T, Ishii K
Journal of pharmacological sciences 2017 Sep 29;
Journal of pharmacological sciences 2017 Sep 29;
Antibody incubation at 37°C improves fluorescent immunolabeling in free-floating thick tissue sections.
Xiao X, Feng YP, Du B, Sun HR, Ding YQ, Qi JG
BioTechniques 2017 Mar 1;62(3):115-122
BioTechniques 2017 Mar 1;62(3):115-122
Methylene Blue promotes cortical neurogenesis and ameliorates behavioral deficit after photothrombotic stroke in rats.
Ahmed ME, Tucker D, Dong Y, Lu Y, Zhao N, Wang R, Zhang Q
Neuroscience 2016 Nov 12;336:39-48
Neuroscience 2016 Nov 12;336:39-48
Gadd45b prevents autophagy and apoptosis against rat cerebral neuron oxygen-glucose deprivation/reperfusion injury.
He G, Xu W, Tong L, Li S, Su S, Tan X, Li C
Apoptosis : an international journal on programmed cell death 2016 Apr;21(4):390-403
Apoptosis : an international journal on programmed cell death 2016 Apr;21(4):390-403
Huwe1 interacts with Gadd45b under oxygen-glucose deprivation and reperfusion injury in primary Rat cortical neuronal cells.
He GQ, Xu WM, Li JF, Li SS, Liu B, Tan XD, Li CQ
Molecular brain 2015 Dec 23;8:88
Molecular brain 2015 Dec 23;8:88
Cell-density-dependent manifestation of partial characteristics for neuronal precursors in a newly established human gliosarcoma cell line.
Yao PS, Kang DZ, Wang XF, Lin RY, Ye ZC
In vitro cellular & developmental biology. Animal 2015 Apr;51(4):345-52
In vitro cellular & developmental biology. Animal 2015 Apr;51(4):345-52
Transplantation of mesenchymal stem cells exerts anti-apoptotic effects in adult rats after spinal cord ischemia-reperfusion injury.
Yin F, Guo L, Meng CY, Liu YJ, Lu RF, Li P, Zhou YB
Brain research 2014 May 2;1561:1-10
Brain research 2014 May 2;1561:1-10
Protein tyrosine phosphatase receptor U (PTPRU) is required for glioma growth and motility.
Zhu Z, Liu Y, Li K, Liu J, Wang H, Sun B, Xiong Z, Jiang H, Zheng J, Hu Z
Carcinogenesis 2014 Aug;35(8):1901-10
Carcinogenesis 2014 Aug;35(8):1901-10
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human brain tissue were subjected to SDS PAGE followed by western blot with 60190-1-Ig(GFAP antibody) at dilution of 1:10000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human brain using 60190-1-Ig(GFAP antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The GFAP antibody from Proteintech is a mouse monoclonal antibody to a recombinant protein of human GFAP. This antibody recognizes human, mouse, rat antigen. The GFAP antibody has been validated for the following applications: ELISA, WB, IHC analysis.
