23495-1-AP

antibody from Proteintech Group

Targeting: UGT1A1 GNT1, UGT1, UGT1A

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Antibody Data

Product number

23495-1-AP

Provider

Proteintech Group

Product name

UGT1A1 antibody

Antibody type

Polyclonal

Description

UGT1A1 antibody (Cat. #23495-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: WB,ELISA.

Reactivity

Human, Mouse

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

Schisandrin B Targets PXR to Enhance Bile Acid Metabolism and Alleviate ANIT-Induced Cholestatic Liver Injury via Dual Pathways.

Zhang Y, Lan H, Yu X, Zhuo L, Zhao B, Liu F, An L, Zhang F, Liu Z, Wang C
International journal of biological sciences 2026;22(1):387-409

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PXR ribosylation at E194 amplifies NAPQI in acetaminophen‒induced liver injury in mice, rescued by Schisandrin B.

Long JC, Liu CX, Wang MY, Liu CH, Zhang F, Liu ZQ, An L, Wang CY
Acta pharmacologica Sinica 2026 Feb;47(2):370-382

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Ursolic acid drug-drug nanocrystals ameliorate cholestatic liver injury via inhibiting oxidative stress and regulating bile acid metabolism.

Hu M, Hua X, Xiong W, Zheng E, Yang X, Lu Y, He B, Zhong X, Jiang Z, Zhang Q, Liu Y
Frontiers in pharmacology 2025;16:1586141

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Huachansu injection enhances anti-colorectal cancer efficacy of irinotecan and alleviates its induced intestinal toxicity through upregulating UGT1A1-OATP1B3 expression in vitro and in vivo.

Jiang B, Meng ZY, Hu YJ, Chen JJ, Zong L, Xu LY, Zhang XQ, Zhang JX, Han YL
Journal of integrative medicine 2025 Sep;23(5):576-590

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Gut bacteria and the host synergies promote resveratrol metabolism and induce tolerance in ALD mice.

Zhang SX, Hu FF, Chen H, Guo J, Xiang ZW, Ding X, Ye ML, Ye WL, Chen JH, Wang X, Han WJ, Zhou HH, Zhang W, Huang Y, Wu LL, Lian GH, Chen Y
NPJ biofilms and microbiomes 2025 Jul 14;11(1):132

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Sodium taurocholate co-transporting polypeptide deficiency attenuates acetaminophen-induced hepatotoxicity via regulating expression of drug metabolism enzymes in mice.

Yang F, Wu L, Xu W, Wu Y, Zhu S, Zhang Y, Chong Y, Peng L
Toxicology and applied pharmacology 2025 Apr;497:117266

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Genetically Modified Hepatocytes Targeting Bilirubin and Ammonia Metabolism for the Construction of Bioartificial Liver System.

Wang K, Zhu Y, Li M, Yang Y, Zuo D, Sheng J, Zhang X, Wang W, Zhou P, Feng M
Biomaterials research 2024;28:0043

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Taraxasterol protects against acetaminophen-induced hepatotoxicity by reducing liver inflammatory response and ameliorating oxidative stress in mice.

Lin W, Gu B, Gu Y, Zhao R, Huang Y, Fan R, Rong W, Liu Z
International immunopharmacology 2024 Sep 10;138:112580

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Dysregulated Glucuronidation of Bilirubin Exacerbates Liver Inflammation and Fibrosis in Schistosomiasis Japonica through the NF-κB Signaling Pathway.

Xue Q, Wang Y, Liu Y, Hua H, Zhou X, Xu Y, Zhang Y, Xiong C, Liu X, Yang K, Huang Y
Pathogens (Basel, Switzerland) 2024 Mar 28;13(4)

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Air-ventilated normothermic mechanical perfusion improves susceptibility to donation after circulatory death and cold preservation-induced cholestatic liver injury through PPAR-γ/UGT1A1 axis.

Wang Y, Tao RL, Yu DS, Wu KW, Bai Y, Yang DJ, Gu Y, Guo WZ, Zhang SJ, Jin Y, Shi JH
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Aug 31;38(16):e70014

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Bicyclol attenuates high fat diet-induced non-alcoholic fatty liver disease/non-alcoholic steatohepatitis through modulating multiple pathways in mice.

Wu J, Jia S, Xu B, Yao X, Shao J, Yao J, Cen D, Yao X
Frontiers in pharmacology 2023;14:1157200

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Peptide-dendrimer-reinforced bioinks for 3D bioprinting of heterogeneous and biomimetic in vitro models.

Zhou K, Ding R, Tao X, Cui Y, Yang J, Mao H, Gu Z
Acta biomaterialia 2023 Oct 1;169:243-255

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NRF2 and FXR dual signaling pathways cooperatively regulate the effects of oleanolic acid on cholestatic liver injury.

Liu J, Liu J, Meng C, Gu Q, Huang C, Liu F, Xia C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jan;108:154529

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The Protective Effect of Sulforaphane on Dextran Sulfate Sodium-Induced Colitis Depends on Gut Microbial and Nrf2-Related Mechanism.

He C, Gao M, Zhang X, Lei P, Yang H, Qing Y, Zhang L
Frontiers in nutrition 2022;9:893344

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The Glycosyltransferase Pathway: An Integrated Analysis of the Cell Metabolome.

Audet-Delage Y, Rouleau M, Villeneuve L, Guillemette C
Metabolites 2022 Oct 21;12(10)

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Oleanolic acid alleviates ANIT-induced cholestatic liver injury by activating Fxr and Nrf2 pathways to ameliorate disordered bile acids homeostasis.

Liu J, Liu J, Meng C, Huang C, Liu F, Xia C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jul 20;102:154173

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Silencing of Aberrant Secretory Protein Expression by Disease-Associated Mutations.

Tikhonova EB, Karamysheva ZN, von Heijne G, Karamyshev AL
Journal of molecular biology 2019 Jun 28;431(14):2567-2580