UGT1A4

gene product
HUG-BR2, UGT1D
This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. This enzyme has some glucuronidase activity towards bilirubin, although is is more active on amines, steroids, and sapogenins. [provided by RefSeq, Jul 2008]
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LifeSpan BioSciences, Inc.
8 antibodies
Invitrogen Antibodies
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Affinity Biosciences
1 antibody
antibodies-online
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GeneTex
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Bioworld Technology, Inc
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Cusabio Biotech Co., Ltd
1 antibody
St John's Laboratory
1 antibody
Biorbyt
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Novus Biologicals
2 antibodies
OriGene
2 antibodies
Aviva Systems Biology
1 antibody
NovoPro Bioscience Inc.
1 antibody
ProSci
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United States Biological
24 antibodies
Abbexa
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MyBioSource
1 antibody
Abgent
1 antibody
Creative Diagnostics
1 antibody
Leading Biology
1 antibody
MilliporeSigma / Merck KGaA
1 antibody