Antibody data
- Antibody Data
- Antigen structure
- References [115]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
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Validation data
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- Product number
- 23660-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- Alpha Actin antibody
- Antibody type
- Polyclonal
- Description
- Alpha Actin antibody (Cat. #23660-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references The FAcilitates Chromatin Transcription complex regulates the ratio of glycolysis to oxidative phosphorylation in neural stem cells.
Targeting PNPO to suppress tumor growth via inhibiting autophagic flux and to reverse paclitaxel resistance in ovarian cancer.
HRD1 reduction promotes cholesterol-induced vascular smooth muscle cell phenotypic change via endoplasmic reticulum stress.
Stevioside Ameliorates Palmitic Acid-Induced Abnormal Glucose Uptake via the PDK4/AMPK/TBC1D1 Pathway in C2C12 Myotubes.
Myricanol improves metabolic profiles in dexamethasone induced lipid and protein metabolism disorders in mice.
QDPR deficiency drives immune suppression in pancreatic cancer.
Leukemia inhibitory factor protects against experimental periodontitis through immuno-modulations of both macrophages and periodontal ligament fibroblasts.
High fat diet ameliorates mitochondrial cardiomyopathy in CHCHD10 mutant mice.
The regulation of MFG-E8 on the mitophagy in diabetic sarcopenia via the HSPA1L-Parkin pathway and the effect of D-pinitol.
d-mannose targets PD-1 to lysosomal degradation and enhances T cell-mediated anti-tumor immunity.
Shenqu xiaoshi oral solution enhances digestive function and stabilizes the gastrointestinal microbiota of juvenile rats with infantile anorexia.
MDM4 was associated with poor prognosis and tumor-immune infiltration of cancers.
Overcoming therapeutic resistance in oncolytic herpes virotherapy by targeting IGF2BP3-induced NETosis in malignant glioma.
Hesperetin promotes bladder cancer cells death via the PI3K/AKT pathway by network pharmacology and molecular docking.
AZD7762 induces CRBN dependent BAG3 degradation through ubiquitin-proteasome pathway.
AMPK/PGC-1α and p53 modulate VDAC1 expression mediated by reduced ATP level and metabolic oxidative stress in neuronal cells.
Endothelium-specific deletion of p62 causes organ fibrosis and cardiac dysfunction.
Nicotinamide protects against diabetic kidney disease through regulation of Sirt1.
Rapamycin protects Sertoli cells against BPA-induced autophagy disorders.
Exercise training affects calcium ion transport by downregulating the CACNA2D1 protein to reduce hypertension-induced myocardial injury in mice.
Pharmacological Activation of Rev-erbα Attenuates Doxorubicin-Induced Cardiotoxicity by PGC-1α Signaling Pathway.
Sema3A Modified PDLSCs Exhibited Enhanced Osteogenic Capabilities and Stimulated Differentiation of Pre-Osteoblasts.
Effect of Tamoxifen on Proteome Expression during In Vitro Myogenesis in Murine Skeletal Muscle C(2)C(12) Cells.
Atorvastatin rescues vascular endothelial injury in hypertension by WWP2-mediated ubiquitination and degradation of ATP5A.
Melatonin alleviates depression-like behaviors and cognitive dysfunction in mice by regulating the circadian rhythm of AQP4 polarization.
Inhibition of Sirt2 Decreases ApoE Secretion in Astrocytes and Microglial Cells.
Depletion of PIEZO1 expression is accompanied by upregulating p53 signaling in mice with perioperative neurocognitive disorder.
ZSCAN4 interacts with PARP1 to promote DNA repair in mouse embryonic stem cells.
Human amnion-derived mesenchymal stem cells improve subclinical hypothyroidism by immunocompetence mediating apoptosis inhibition on thyroid cells in aged mice.
CCDC127 regulates lipid droplet homeostasis by enhancing mitochondria-ER contacts.
NUAK1 promotes tumor metastasis through upregulating slug transcription in esophageal squamous cell carcinoma.
Active post-transcriptional regulation and ACLY-mediated acetyl-CoA synthesis as a pivotal target of Shuang-Huang-Sheng-Bai formula for lung adenocarcinoma treatment.
Down-regulation of WWP2 aggravates Type 2 diabetes mellitus-induced vascular endothelial injury through modulating ubiquitination and degradation of DDX3X.
ACTA1 H40Y mutant iPSC-derived skeletal myocytes display mitochondrial defects in an in vitro model of nemaline myopathy.
Rare sugar L-sorbose exerts antitumor activity by impairing glucose metabolism.
Inhibition of TLR4 Alleviates Heat Stroke-Induced Cardiomyocyte Injury by Down-Regulating Inflammation and Ferroptosis.
Gallocatechin Gallate Inhibits the Replication of Pseudorabies Virus via Suppressing the Entry and Release Stages in Its Replication Cycle.
Sleep Deprivation Promotes Endothelial Inflammation and Atherogenesis by Reducing Exosomal miR-182-5p.
The Valsa Mali effector Vm1G-1794 protects the aggregated MdEF-Tu from autophagic degradation to promote infection in apple.
5'-tiRNA-Gln inhibits hepatocellular carcinoma progression by repressing translation through the interaction with eukaryotic initiation factor 4A-I.
MFN2 deficiency affects calcium homeostasis in lung adenocarcinoma cells via downregulation of UCP4.
Aloe-emodin ameliorated MI-induced cardiac remodeling in mice via inhibiting TGF-β/SMAD signaling via up-regulating SMAD7.
Curcumol, a major terpenoid from Curcumae Rhizoma, attenuates human uterine leiomyoma cell development via the p38MAPK/NF-κB pathway.
CaMKK2 alleviates myocardial ischemia/reperfusion injury by inhibiting oxidative stress and inflammation via the action on the AMPK-AKT-GSK-3β/Nrf2 signaling cascade.
Nucleolus assembly impairment leads to two-cell transcriptional repression via NPM1-mediated PRC2 recruitment.
NCOA7 Regulates Growth and Metastasis of Clear Cell Renal Cell Carcinoma via MAPK/ERK Signaling Pathway.
HMOX1 Promotes Ferroptosis Induced by Erastin in Lens Epithelial Cell through Modulates Fe(2+) Production.
The protective effect of inhibiting mitochondrial fission on the juvenile rat brain following PTZ kindling through inhibiting the BCL2L13/LC3 mitophagy pathway.
G9a inhibition promotes the formation of pacemaker-like cells by reducing the enrichment of H3K9me2 in the HCN4 promoter region.
Lenvatinib inhibits intrahepatic cholangiocarcinoma via Gadd45a-mediated cell cycle arrest.
SIRT3 promotes metabolic maturation of human iPSC-derived cardiomyocytes via OPA1-controlled mitochondrial dynamics.
LOC102549726/miR-760-3p network is involved in the progression of ISO-induced pathological cardiomyocyte hypertrophy via endoplasmic reticulum stress.
miR-146a-5p Modulates Adult Hippocampal Neurogenesis Deficits Through Klf4/p-Stat3 Signaling in APP/PS1 Mice.
Orexin-A Reverse Bone Mass Loss Induced by Chronic Intermittent Hypoxia Through OX1R-Nrf2/HIF-1α Pathway.
DJ-1 promotes osteosarcoma progression through activating CDK4/RB/E2F1 signaling pathway.
Multi-Omics Analysis of MCM2 as a Promising Biomarker in Pan-Cancer.
Targeting p65 to inhibit Cas3 transcription by Onjisaponin B for radiation damage therapy in p65+/- mice.
Hace1 overexpression mitigates myocardial hypoxia/reoxygenation injury via the effects on Keap1/Nrf2 pathway.
CAMSAP2 promotes colorectal cancer cell migration and invasion through activation of JNK/c-Jun/MMP-1 signaling pathway.
LINC00514 facilitates cell proliferation, migration, invasion, and epithelial-mesenchymal transition in non-small cell lung cancer by acting on the Wnt/β-catenin signaling pathway.
Scutellarein protects against cardiac hypertrophy via suppressing TRAF2/NF-κB signaling pathway.
Chlorine disinfection elevates the toxicity of polystyrene microplastics to human cells by inducing mitochondria-dependent apoptosis.
TXNIP knockout improves cardiac function after myocardial infarction by promoting angiogenesis and reducing cardiomyocyte apoptosis.
Erectile dysfunction in hypospadiac male adult rats induced by maternal exposure to di-n-butyl phthalate.
LncRNA BACE1-AS promotes the progression of osteosarcoma through miR-762/SOX7 axis.
ZC3H4 promotes pulmonary fibrosis via an ER stress-related positive feedback loop.
BUB1B (BUB1 Mitotic Checkpoint Serine/Threonine Kinase B) promotes lung adenocarcinoma by interacting with Zinc Finger Protein ZNF143 and regulating glycolysis.
Design, synthesis and biological evaluation of novel 1,3,4,9-tetrahydropyrano[3,4-b]indoles as potential treatment of triple negative breast cancer by suppressing PI3K/AKT/mTOR pathway.
The RNA polymerase of cytoplasmically replicating Zika virus binds with chromatin DNA in nuclei and regulates host gene transcription.
Functional investigation of SLC1A2 variants associated with epilepsy.
RSL3 triggers glioma stem cell differentiation via the Tgm2/AKT/ID1 signaling axis.
Mitochondrial dysfunction by TFAM depletion disrupts self-renewal and lineage differentiation of human PSCs by affecting cell proliferation and YAP response.
Luteolin alleviates cognitive impairment in Alzheimer's disease mouse model via inhibiting endoplasmic reticulum stress-dependent neuroinflammation.
NAP1L5 Promotes Nucleolar Hypertrophy and Is Required for Translation Activation During Cardiomyocyte Hypertrophy.
JNK signaling-dependent regulation of histone acetylation are involved in anacardic acid alleviates cardiomyocyte hypertrophy induced by phenylephrine.
Interactions between the ERK1/2 signaling pathway and PCAF play a key role in PE‑induced cardiomyocyte hypertrophy.
Diosgenin exerts anti-tumor effects through inactivation of cAMP/PKA/CREB signaling pathway in colorectal cancer.
A novel SIRT6 activator ameliorates neuroinflammation and ischemic brain injury via EZH2/FOXC1 axis.
PGC1α Promotes Cisplatin Resistance in Ovarian Cancer by Regulating the HSP70/HK2/VDAC1 Signaling Pathway.
Overexpression of retinoid X receptor beta provides protection against oxidized low-density lipoprotein-induced inflammation via regulating PGC1α-dependent mitochondrial homeostasis in endothelial cells.
Different roles of BAG3 in cardiac physiological hypertrophy and pathological remodeling.
Betulinic acid attenuated bleomycin-induced pulmonary fibrosis by effectively intervening Wnt/β-catenin signaling.
USP15 participates in DBP-induced testicular oxidative stress injury through regulating the Keap1/Nrf2 signaling pathway.
Pygo1 regulates pathological cardiac hypertrophy via a β-catenin-dependent mechanism.
5-Azacytidine-Induced Cardiomyocyte Differentiation of Very Small Embryonic-Like Stem Cells.
Prognostic Significance and Related Mechanisms of Hexokinase 1 in Ovarian Cancer.
Evaluation of toxicity of halloysite nanotubes and multi-walled carbon nanotubes to endothelial cells in vitro and blood vessels in vivo.
USP22 promotes proliferation in renal cell carcinoma by stabilizing survivin.
Identification of miR-515-3p and its targets, vimentin and MMP3, as a key regulatory mechanism in esophageal cancer metastasis: functional and clinical significance.
The roles of dipeptidyl peptidase-4 and its inhibitors in the regulation of airway epithelial-mesenchymal transition.
Ginsenoside Rg3 promotes regression from hepatic fibrosis through reducing inflammation-mediated autophagy signaling pathway.
AMPK decreases ERK1/2 activity and cancer cell sensitivity to nutrition deprivation by mediating a positive feedback loop involving eEF2K.
Fucoxanthin inhibits hepatic oxidative stress, inflammation, and fibrosis in diet-induced nonalcoholic steatohepatitis model mice.
Moderate-Intensity Continuous Training Improves FGF21 and KLB Expression in Obese Mice.
CFIm25-regulated lncRNA acv3UTR promotes gastric tumorigenesis via miR-590-5p/YAP1 axis.
Therapeutic Effects of Human Urine-Derived Stem Cells in a Rat Model of Cisplatin-Induced Acute Kidney Injury In Vivo and In Vitro.
miR-30a-3p Targets MAD2L1 and Regulates Proliferation of Gastric Cancer Cells.
MicroRNA-92b-3p suppresses angiotensin II-induced cardiomyocyte hypertrophy via targeting HAND2.
CUDC-907 displays potent antitumor activity against human pancreatic adenocarcinoma in vitro and in vivo through inhibition of HDAC6 to downregulate c-Myc expression.
FAM83D inhibits autophagy and promotes proliferation and invasion of ovarian cancer cells via PI3K/AKT/mTOR pathway.
lncRNA TUG1 Promotes Cisplatin Resistance by Regulating CCND2 via Epigenetically Silencing miR-194-5p in Bladder Cancer.
Long noncoding RNA Neat1 modulates myogenesis by recruiting Ezh2.
Function of BRD4 in the pathogenesis of high glucose‑induced cardiac hypertrophy.
Epigallocatechin-3-gallate inhibits angiotensin II-induced cardiomyocyte hypertrophy via regulating Hippo signaling pathway in H9c2 rat cardiomyocytes.
Thioredoxin-interacting protein deficiency ameliorates kidney inflammation and fibrosis in mice with unilateral ureteral obstruction.
Gemin5 plays a role in unassembled-U1 snRNA disposal in SMN-deficient cells.
Dihydroartemisinin inhibits the viability of cervical cancer cells by upregulating caveolin 1 and mitochondrial carrier homolog 2: Involvement of p53 activation and NAD(P)H:quinone oxidoreductase 1 downregulation.
L-PGDS Mediates Vagus Nerve Stimulation-Induced Neuroprotection in a Rat Model of Ischemic Stroke by Suppressing the Apoptotic Response.
Overexpression of TRIB3 promotes angiogenesis in human gastric cancer.
Loss of Mouse P2Y6 Nucleotide Receptor Is Associated with Physiological Macrocardia and Amplified Pathological Cardiac Hypertrophy.
Vinexin β Interacts with Hepatitis C Virus NS5A, Modulating Its Hyperphosphorylation To Regulate Viral Propagation.
Transgenic mice overexpressing glia maturation factor-β, an oxidative stress inducible gene, show premature aging due to Zmpste24 down-regulation.
Actin-induced dimerization of palladin promotes actin-bundling.
DEAD-box RNA helicase DDX3X inhibits DENV replication via regulating type one interferon pathway.
Oncogenic miR-17/20a Forms a Positive Feed-forward Loop with the p53 Kinase DAPK3 to Promote Tumorigenesis.
Lou Y, Wu L, Cai W, Deng H, Sang R, Xie S, Xu X, Yuan X, Wu C, Xu M, Ge W, Xi Y, Yang X
Journal of molecular cell biology 2024 Sep 30;16(4)
Journal of molecular cell biology 2024 Sep 30;16(4)
Targeting PNPO to suppress tumor growth via inhibiting autophagic flux and to reverse paclitaxel resistance in ovarian cancer.
Li X, Guan W, Liu H, Yuan J, Wang F, Guan B, Chen J, Lu Q, Zhang L, Xu G
Apoptosis : an international journal on programmed cell death 2024 Oct;29(9-10):1546-1563
Apoptosis : an international journal on programmed cell death 2024 Oct;29(9-10):1546-1563
HRD1 reduction promotes cholesterol-induced vascular smooth muscle cell phenotypic change via endoplasmic reticulum stress.
Wang L, Ren Z, Wu L, Zhang X, Wang M, Niu H, He X, Wang H, Chen Y, Shi G, Qian X
Molecular and cellular biochemistry 2024 Nov;479(11):3021-3036
Molecular and cellular biochemistry 2024 Nov;479(11):3021-3036
Stevioside Ameliorates Palmitic Acid-Induced Abnormal Glucose Uptake via the PDK4/AMPK/TBC1D1 Pathway in C2C12 Myotubes.
Zhang C, Li S, Li L, Wang R, Luo S, Li G
Endocrinology, diabetes & metabolism 2024 May;7(3):e00482
Endocrinology, diabetes & metabolism 2024 May;7(3):e00482
Myricanol improves metabolic profiles in dexamethasone induced lipid and protein metabolism disorders in mice.
Li T, Hu X, Fan L, Yang Y, He K
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 May;174:116557
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 May;174:116557
QDPR deficiency drives immune suppression in pancreatic cancer.
Liu J, He X, Deng S, Zhao S, Zhang S, Chen Z, Xue C, Zeng L, Zhao H, Zhou Y, Bai R, Xu Z, Liu S, Zhou Q, Li M, Zhang J, Huang X, Chen R, Wang L, Lin D, Zheng J
Cell metabolism 2024 May 7;36(5):984-999.e8
Cell metabolism 2024 May 7;36(5):984-999.e8
Leukemia inhibitory factor protects against experimental periodontitis through immuno-modulations of both macrophages and periodontal ligament fibroblasts.
Ou Y, Fan L, Wang X, Xia H, Cheng M, Huang J, Liang Y, Wang Y, Zhou Y
Journal of periodontology 2024 Mar 15;
Journal of periodontology 2024 Mar 15;
High fat diet ameliorates mitochondrial cardiomyopathy in CHCHD10 mutant mice.
Southwell N, Manzo O, Bacman S, Zhao D, Sayles NM, Dash J, Fujita K, D'Aurelio M, Di Lorenzo A, Manfredi G, Kawamata H
EMBO molecular medicine 2024 Jun;16(6):1352-1378
EMBO molecular medicine 2024 Jun;16(6):1352-1378
The regulation of MFG-E8 on the mitophagy in diabetic sarcopenia via the HSPA1L-Parkin pathway and the effect of D-pinitol.
Zhao W, Zhao B, Meng X, Li B, Wang Y, Yu F, Fu C, Yu X, Li X, Dai C, Wang J, Gao H, Cheng M
Journal of cachexia, sarcopenia and muscle 2024 Jun;15(3):934-948
Journal of cachexia, sarcopenia and muscle 2024 Jun;15(3):934-948
d-mannose targets PD-1 to lysosomal degradation and enhances T cell-mediated anti-tumor immunity.
Dong W, Lin M, Zhang R, Sun X, Li H, Liu T, Xu Y, Lv L
Cancer letters 2024 Jun 1;591:216883
Cancer letters 2024 Jun 1;591:216883
Shenqu xiaoshi oral solution enhances digestive function and stabilizes the gastrointestinal microbiota of juvenile rats with infantile anorexia.
Zhao M, Xiang T, Dong Z, Liu G, Wang P, Qi X, Hao Q, Han N, Liu Z, Li S, Yin J, Zhai J
Journal of ethnopharmacology 2024 Jan 30;319(Pt 1):117112
Journal of ethnopharmacology 2024 Jan 30;319(Pt 1):117112
MDM4 was associated with poor prognosis and tumor-immune infiltration of cancers.
Liu J, Yang J, Pan Q, Wang X, Wang X, Chen H, Zheng X, Huang Q
European journal of medical research 2024 Jan 27;29(1):79
European journal of medical research 2024 Jan 27;29(1):79
Overcoming therapeutic resistance in oncolytic herpes virotherapy by targeting IGF2BP3-induced NETosis in malignant glioma.
Dai W, Tian R, Yu L, Bian S, Chen Y, Yin B, Luan Y, Chen S, Fan Z, Yan R, Pan X, Hou Y, Li R, Chen J, Shu M
Nature communications 2024 Jan 2;15(1):131
Nature communications 2024 Jan 2;15(1):131
Hesperetin promotes bladder cancer cells death via the PI3K/AKT pathway by network pharmacology and molecular docking.
Lv Y, Liu Z, Deng L, Xia S, Mu Q, Xiao B, Xiu Y, Liu Z
Scientific reports 2024 Jan 10;14(1):1009
Scientific reports 2024 Jan 10;14(1):1009
AZD7762 induces CRBN dependent BAG3 degradation through ubiquitin-proteasome pathway.
Liao Y, Yuan C, Huang M, Si W, Li D, Wu W, Zhang S, Wu R, Quan Y, Yu X, Liao S
Anti-cancer drugs 2024 Jan 1;35(1):46-54
Anti-cancer drugs 2024 Jan 1;35(1):46-54
AMPK/PGC-1α and p53 modulate VDAC1 expression mediated by reduced ATP level and metabolic oxidative stress in neuronal cells.
Wang Z, Xu T, Sun Y, Zhang X, Wang X
Acta biochimica et biophysica Sinica 2024 Feb 25;56(2):162-173
Acta biochimica et biophysica Sinica 2024 Feb 25;56(2):162-173
Endothelium-specific deletion of p62 causes organ fibrosis and cardiac dysfunction.
Feng J, Li Y, Zhang Y, Sun S, Sun J, Xu Q, Ji X, Liu Y, Wan Q
Journal of translational medicine 2024 Feb 16;22(1):161
Journal of translational medicine 2024 Feb 16;22(1):161
Nicotinamide protects against diabetic kidney disease through regulation of Sirt1.
Yang Y, Huang J, Xie L, Wang Y, Guo S, Wang M, Shao X, Liu W, Wang Y, Li Q, Wu X, Zhang Z, Zeng F, Gong W
Endocrine 2024 Aug;85(2):638-648
Endocrine 2024 Aug;85(2):638-648
Rapamycin protects Sertoli cells against BPA-induced autophagy disorders.
Nie J, Mao Z, Zeng X, Zhao X
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Apr;186:114510
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Apr;186:114510
Exercise training affects calcium ion transport by downregulating the CACNA2D1 protein to reduce hypertension-induced myocardial injury in mice.
Gao S, Yao W, Zhou R, Pei Z
iScience 2024 Apr 19;27(4):109351
iScience 2024 Apr 19;27(4):109351
Pharmacological Activation of Rev-erbα Attenuates Doxorubicin-Induced Cardiotoxicity by PGC-1α Signaling Pathway.
Zou R, Wang S, Cai H, Wang Y, Wang C
Cardiovascular therapeutics 2023;2023:2108584
Cardiovascular therapeutics 2023;2023:2108584
Sema3A Modified PDLSCs Exhibited Enhanced Osteogenic Capabilities and Stimulated Differentiation of Pre-Osteoblasts.
Wang W, Chen B, Yang J, Li Y, Ding H, Liu H, Yuan C
Cell biochemistry and biophysics 2023 Sep;81(3):543-552
Cell biochemistry and biophysics 2023 Sep;81(3):543-552
Effect of Tamoxifen on Proteome Expression during In Vitro Myogenesis in Murine Skeletal Muscle C(2)C(12) Cells.
Morris EA, Abreu A, Scordilis SP
Journal of proteome research 2023 Sep 1;22(9):3040-3053
Journal of proteome research 2023 Sep 1;22(9):3040-3053
Atorvastatin rescues vascular endothelial injury in hypertension by WWP2-mediated ubiquitination and degradation of ATP5A.
Yin Z, You S, Zhang S, Zhang L, Wu B, Huang X, Lu S, Cao L, Zhang Y, Li D, Zhang X, Liu J, Sun Y, Zhang N
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Oct;166:115228
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Oct;166:115228
Melatonin alleviates depression-like behaviors and cognitive dysfunction in mice by regulating the circadian rhythm of AQP4 polarization.
Yao D, Li R, Hao J, Huang H, Wang X, Ran L, Fang Y, He Y, Wang W, Liu X, Wang M
Translational psychiatry 2023 Oct 6;13(1):310
Translational psychiatry 2023 Oct 6;13(1):310
Inhibition of Sirt2 Decreases ApoE Secretion in Astrocytes and Microglial Cells.
Chen Y, Zhou C, Abdelhamid M, Jung CG, Michikawa M
Journal of biochemistry 2023 Oct 31;174(5):409-420
Journal of biochemistry 2023 Oct 31;174(5):409-420
Depletion of PIEZO1 expression is accompanied by upregulating p53 signaling in mice with perioperative neurocognitive disorder.
Bai F, Huang L, Long Z, Zhang M, Deng Q, Huang J, Bao X, Hao X, Li H
Functional & integrative genomics 2023 Oct 27;23(4):327
Functional & integrative genomics 2023 Oct 27;23(4):327
ZSCAN4 interacts with PARP1 to promote DNA repair in mouse embryonic stem cells.
Tsai LK, Peng M, Chang CC, Wen L, Liu L, Liang X, Chen YE, Xu J, Sung LY
Cell & bioscience 2023 Oct 24;13(1):193
Cell & bioscience 2023 Oct 24;13(1):193
Human amnion-derived mesenchymal stem cells improve subclinical hypothyroidism by immunocompetence mediating apoptosis inhibition on thyroid cells in aged mice.
Li C, Rui Q, Dong X, Ning S, Zhou J, Wu H, Jiang C, Cui Y, Liu J, Jiang J, Qin L
Cell and tissue research 2023 Nov;394(2):309-323
Cell and tissue research 2023 Nov;394(2):309-323
CCDC127 regulates lipid droplet homeostasis by enhancing mitochondria-ER contacts.
Xia Y, Zhang Y, Sun Y, He L
Biochemical and biophysical research communications 2023 Nov 26;683:149116
Biochemical and biophysical research communications 2023 Nov 26;683:149116
NUAK1 promotes tumor metastasis through upregulating slug transcription in esophageal squamous cell carcinoma.
Yang H, Wei Z, Song Y, Du K, Yin N, Lu H, Li B, Hou L, Xing P, Chen L, Wang C, Xie S
Cancer cell international 2023 Nov 2;23(1):258
Cancer cell international 2023 Nov 2;23(1):258
Active post-transcriptional regulation and ACLY-mediated acetyl-CoA synthesis as a pivotal target of Shuang-Huang-Sheng-Bai formula for lung adenocarcinoma treatment.
Liu D, Dong C, Wang F, Liu W, Jin X, Qi SL, Liu L, Jin Q, Wang S, Wu J, Wang C, Yang J, Deng H, Cai Y, Yang L, Qin J, Zhang C, Yang X, Wang MS, Yu G, Xue YW, Wang Z, Ge GB, Xu Z, Chen WL
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 May;113:154732
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 May;113:154732
Down-regulation of WWP2 aggravates Type 2 diabetes mellitus-induced vascular endothelial injury through modulating ubiquitination and degradation of DDX3X.
You S, Xu J, Yin Z, Wu B, Wang P, Hao M, Cheng C, Liu M, Zhao Y, Jia P, Jiang H, Li D, Cao L, Zhang X, Zhang Y, Sun Y, Zhang N
Cardiovascular diabetology 2023 May 6;22(1):107
Cardiovascular diabetology 2023 May 6;22(1):107
ACTA1 H40Y mutant iPSC-derived skeletal myocytes display mitochondrial defects in an in vitro model of nemaline myopathy.
Gartz M, Haberman M, Sutton J, Slick RA, Luttrell SM, Mack DL, Lawlor MW
Experimental cell research 2023 Mar 15;424(2):113507
Experimental cell research 2023 Mar 15;424(2):113507
Rare sugar L-sorbose exerts antitumor activity by impairing glucose metabolism.
Xu HL, Zhou X, Chen S, Xu S, Li Z, Nakanishi H, Gao XD
Communications biology 2023 Mar 11;6(1):259
Communications biology 2023 Mar 11;6(1):259
Inhibition of TLR4 Alleviates Heat Stroke-Induced Cardiomyocyte Injury by Down-Regulating Inflammation and Ferroptosis.
Chen D, Geng Y, Deng Z, Li P, Xue S, Xu T, Li G
Molecules (Basel, Switzerland) 2023 Mar 1;28(5)
Molecules (Basel, Switzerland) 2023 Mar 1;28(5)
Gallocatechin Gallate Inhibits the Replication of Pseudorabies Virus via Suppressing the Entry and Release Stages in Its Replication Cycle.
Bo Z, Zhu J, Guo M, Zhang C, Cao Y, Zhang X, Wu Y
Veterinary sciences 2023 Mar 1;10(3)
Veterinary sciences 2023 Mar 1;10(3)
Sleep Deprivation Promotes Endothelial Inflammation and Atherogenesis by Reducing Exosomal miR-182-5p.
Li X, Cao Y, Xu X, Wang C, Ni Q, Lv X, Yang C, Zhang Z, Qi X, Song G
Arteriosclerosis, thrombosis, and vascular biology 2023 Jun;43(6):995-1014
Arteriosclerosis, thrombosis, and vascular biology 2023 Jun;43(6):995-1014
The Valsa Mali effector Vm1G-1794 protects the aggregated MdEF-Tu from autophagic degradation to promote infection in apple.
Che R, Liu C, Wang Q, Tu W, Wang P, Li C, Gong X, Mao K, Feng H, Huang L, Li P, Ma F
Autophagy 2023 Jun;19(6):1745-1763
Autophagy 2023 Jun;19(6):1745-1763
5'-tiRNA-Gln inhibits hepatocellular carcinoma progression by repressing translation through the interaction with eukaryotic initiation factor 4A-I.
Wu C, Liu D, Zhang L, Wang J, Ding Y, Sun Z, Wang W
Frontiers of medicine 2023 Jun;17(3):476-492
Frontiers of medicine 2023 Jun;17(3):476-492
MFN2 deficiency affects calcium homeostasis in lung adenocarcinoma cells via downregulation of UCP4.
Zhang J, Pan L, Zhang Q, Zhao Y, Wang W, Lin N, Zhang S, Wu Q
FEBS open bio 2023 Jun;13(6):1107-1124
FEBS open bio 2023 Jun;13(6):1107-1124
Aloe-emodin ameliorated MI-induced cardiac remodeling in mice via inhibiting TGF-β/SMAD signaling via up-regulating SMAD7.
Yu J, Zhao X, Yan X, Li W, Liu Y, Wang J, Wang J, Yang Y, Hao Y, Liang Z, Tao Y, Yuan Y, Du Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jun;114:154793
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jun;114:154793
Curcumol, a major terpenoid from Curcumae Rhizoma, attenuates human uterine leiomyoma cell development via the p38MAPK/NF-κB pathway.
Yu YH, Zhang HJ, Yang F, Xu L, Liu H
Journal of ethnopharmacology 2023 Jun 28;310:116311
Journal of ethnopharmacology 2023 Jun 28;310:116311
CaMKK2 alleviates myocardial ischemia/reperfusion injury by inhibiting oxidative stress and inflammation via the action on the AMPK-AKT-GSK-3β/Nrf2 signaling cascade.
Li C, Hao J, Qiu H, Xin H
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2023 Jul;72(7):1409-1425
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2023 Jul;72(7):1409-1425
Nucleolus assembly impairment leads to two-cell transcriptional repression via NPM1-mediated PRC2 recruitment.
Li D, Cao R, Li Q, Yang Y, Tang A, Zhang J, Liu Q
Nature structural & molecular biology 2023 Jul;30(7):914-925
Nature structural & molecular biology 2023 Jul;30(7):914-925
NCOA7 Regulates Growth and Metastasis of Clear Cell Renal Cell Carcinoma via MAPK/ERK Signaling Pathway.
Guo J, Ke S, Chen Q, Zhou J, Guo J, Qiu T
International journal of molecular sciences 2023 Jul 18;24(14)
International journal of molecular sciences 2023 Jul 18;24(14)
HMOX1 Promotes Ferroptosis Induced by Erastin in Lens Epithelial Cell through Modulates Fe(2+) Production.
Liao S, Huang M, Liao Y, Yuan C
Current eye research 2023 Jan;48(1):25-33
Current eye research 2023 Jan;48(1):25-33
The protective effect of inhibiting mitochondrial fission on the juvenile rat brain following PTZ kindling through inhibiting the BCL2L13/LC3 mitophagy pathway.
Fang Q, Zheng S, Chen Q, Chen L, Yang Y, Wang Y, Zhang H, Chen J
Metabolic brain disease 2023 Feb;38(2):453-466
Metabolic brain disease 2023 Feb;38(2):453-466
G9a inhibition promotes the formation of pacemaker-like cells by reducing the enrichment of H3K9me2 in the HCN4 promoter region.
Xu P, Jin K, Zhou J, Gu J, Gu X, Dong L, Sun X
Molecular medicine reports 2023 Feb;27(2)
Molecular medicine reports 2023 Feb;27(2)
Lenvatinib inhibits intrahepatic cholangiocarcinoma via Gadd45a-mediated cell cycle arrest.
Yan X, Wang D, Ning Z, Meng ZQ
Discover oncology 2023 Feb 23;14(1):26
Discover oncology 2023 Feb 23;14(1):26
SIRT3 promotes metabolic maturation of human iPSC-derived cardiomyocytes via OPA1-controlled mitochondrial dynamics.
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Free radical biology & medicine 2023 Feb 1;195:270-282
Free radical biology & medicine 2023 Feb 1;195:270-282
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Chen B, Tan L, Wang Y, Yang L, Liu J, Chen D, Huang S, Mao F, Lian J
Journal of molecular histology 2023 Dec;54(6):675-687
Journal of molecular histology 2023 Dec;54(6):675-687
miR-146a-5p Modulates Adult Hippocampal Neurogenesis Deficits Through Klf4/p-Stat3 Signaling in APP/PS1 Mice.
Deng LJ, Wu D, Yang XF, Li T
Neuroscience 2023 Aug 21;526:314-325
Neuroscience 2023 Aug 21;526:314-325
Orexin-A Reverse Bone Mass Loss Induced by Chronic Intermittent Hypoxia Through OX1R-Nrf2/HIF-1α Pathway.
Gu H, Ru Y, Wang W, Cai G, Gu L, Ye J, Zhang WB, Wang L
Drug design, development and therapy 2022;16:2145-2160
Drug design, development and therapy 2022;16:2145-2160
DJ-1 promotes osteosarcoma progression through activating CDK4/RB/E2F1 signaling pathway.
Han Z, Wang L, Wang D, Zhang L, Bi Y, Zheng X, Liu W, Bai G, Wang Z, Wan W, Ma Y, Cai X, Liu T, Jia Q
Frontiers in oncology 2022;12:1036401
Frontiers in oncology 2022;12:1036401
Multi-Omics Analysis of MCM2 as a Promising Biomarker in Pan-Cancer.
Yuan J, Lan H, Huang D, Guo X, Liu C, Liu S, Zhang P, Cheng Y, Xiao S
Frontiers in cell and developmental biology 2022;10:852135
Frontiers in cell and developmental biology 2022;10:852135
Targeting p65 to inhibit Cas3 transcription by Onjisaponin B for radiation damage therapy in p65+/- mice.
Wang TY, Hu YJ, Wang X, Li YF, Zhang F, Yan YD, Dou WT, Cheng CY, Xu P
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Sep;104:154317
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Sep;104:154317
Hace1 overexpression mitigates myocardial hypoxia/reoxygenation injury via the effects on Keap1/Nrf2 pathway.
Chen TY, Zheng SK
In vitro cellular & developmental biology. Animal 2022 Oct;58(9):830-839
In vitro cellular & developmental biology. Animal 2022 Oct;58(9):830-839
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Wang X, Liu Y, Ding Y, Feng G
Scientific reports 2022 Oct 7;12(1):16899
Scientific reports 2022 Oct 7;12(1):16899
LINC00514 facilitates cell proliferation, migration, invasion, and epithelial-mesenchymal transition in non-small cell lung cancer by acting on the Wnt/β-catenin signaling pathway.
Zhu Y, Wu H, Yang X, Xiong Z, Zhao T, Gan X
Bioengineered 2022 May;13(5):13654-13666
Bioengineered 2022 May;13(5):13654-13666
Scutellarein protects against cardiac hypertrophy via suppressing TRAF2/NF-κB signaling pathway.
Shi X, Hu Y, Jiang Y, Wu J, Zhang C, Zhang J, Wu S, Wu Y, Dong W, Li J
Molecular biology reports 2022 Mar;49(3):2085-2095
Molecular biology reports 2022 Mar;49(3):2085-2095
Chlorine disinfection elevates the toxicity of polystyrene microplastics to human cells by inducing mitochondria-dependent apoptosis.
Qin J, Xia PF, Yuan XZ, Wang SG
Journal of hazardous materials 2022 Mar 5;425:127842
Journal of hazardous materials 2022 Mar 5;425:127842
TXNIP knockout improves cardiac function after myocardial infarction by promoting angiogenesis and reducing cardiomyocyte apoptosis.
Wang J, Wang XJ, Zhang Y, Shi WJ, Lei ZD, Jiao XY
Cardiovascular diagnosis and therapy 2022 Jun;12(3):289-304
Cardiovascular diagnosis and therapy 2022 Jun;12(3):289-304
Erectile dysfunction in hypospadiac male adult rats induced by maternal exposure to di-n-butyl phthalate.
Zhou X, Wang S, Zhou R, Zhang T, Wang Y, Zhang Q, Cong R, Ji C, Luan J, Yao L, Zhou X, Song N
Toxicology 2022 Jun 15;475:153227
Toxicology 2022 Jun 15;475:153227
LncRNA BACE1-AS promotes the progression of osteosarcoma through miR-762/SOX7 axis.
Wang C, Zhang T, Yang L, Na X, Qu Y
Molecular biology reports 2022 Jul;49(7):5853-5862
Molecular biology reports 2022 Jul;49(7):5853-5862
ZC3H4 promotes pulmonary fibrosis via an ER stress-related positive feedback loop.
Ghafoor H, Chu H, Huang J, Chen M, Wang S, Wang J, Chao J
Toxicology and applied pharmacology 2022 Jan 15;435:115856
Toxicology and applied pharmacology 2022 Jan 15;435:115856
BUB1B (BUB1 Mitotic Checkpoint Serine/Threonine Kinase B) promotes lung adenocarcinoma by interacting with Zinc Finger Protein ZNF143 and regulating glycolysis.
Zhou X, Yuan Y, Kuang H, Tang B, Zhang H, Zhang M
Bioengineered 2022 Feb;13(2):2471-2485
Bioengineered 2022 Feb;13(2):2471-2485
Design, synthesis and biological evaluation of novel 1,3,4,9-tetrahydropyrano[3,4-b]indoles as potential treatment of triple negative breast cancer by suppressing PI3K/AKT/mTOR pathway.
Qin J, Sun X, Ma Y, Cheng Y, Ma Q, Jing W, Qu S, Liu L
Bioorganic & medicinal chemistry 2022 Feb 1;55:116594
Bioorganic & medicinal chemistry 2022 Feb 1;55:116594
The RNA polymerase of cytoplasmically replicating Zika virus binds with chromatin DNA in nuclei and regulates host gene transcription.
Li P, Wu J, Liu S, Lu R, Jiang H, Wang N, Luo M, Guo L, Xiao J, Bu L, Liu L, Xing F, Peng H, Li C, Ma L, Zhao B, Zhou Z, Guo D
Proceedings of the National Academy of Sciences of the United States of America 2022 Dec 6;119(49):e2205013119
Proceedings of the National Academy of Sciences of the United States of America 2022 Dec 6;119(49):e2205013119
Functional investigation of SLC1A2 variants associated with epilepsy.
Qu Q, Zhang W, Wang J, Mai D, Ren S, Qu S, Zhang Y
Cell death & disease 2022 Dec 21;13(12):1063
Cell death & disease 2022 Dec 21;13(12):1063
RSL3 triggers glioma stem cell differentiation via the Tgm2/AKT/ID1 signaling axis.
Li M, Song D, Chen X, Wang X, Xu L, Yang M, Yang J, Kalvakolanu DV, Wei X, Liu X, Li Y, Guo B, Zhang L
Biochimica et biophysica acta. Molecular basis of disease 2022 Dec 1;1868(12):166529
Biochimica et biophysica acta. Molecular basis of disease 2022 Dec 1;1868(12):166529
Mitochondrial dysfunction by TFAM depletion disrupts self-renewal and lineage differentiation of human PSCs by affecting cell proliferation and YAP response.
Qi Y, Ye Y, Wang R, Yu S, Zhang Y, Lv J, Jin W, Xia S, Jiang W, Li Y, Zhang D
Redox biology 2022 Apr;50:102248
Redox biology 2022 Apr;50:102248
Luteolin alleviates cognitive impairment in Alzheimer's disease mouse model via inhibiting endoplasmic reticulum stress-dependent neuroinflammation.
Kou JJ, Shi JZ, He YY, Hao JJ, Zhang HY, Luo DM, Song JK, Yan Y, Xie XM, Du GH, Pang XB
Acta pharmacologica Sinica 2022 Apr;43(4):840-849
Acta pharmacologica Sinica 2022 Apr;43(4):840-849
NAP1L5 Promotes Nucleolar Hypertrophy and Is Required for Translation Activation During Cardiomyocyte Hypertrophy.
Guo N, Zheng D, Sun J, Lv J, Wang S, Fang Y, Zhao Z, Zeng S, Guo Q, Tong J, Wang Z
Frontiers in cardiovascular medicine 2021;8:791501
Frontiers in cardiovascular medicine 2021;8:791501
JNK signaling-dependent regulation of histone acetylation are involved in anacardic acid alleviates cardiomyocyte hypertrophy induced by phenylephrine.
Peng B, Peng C, Luo X, Wu S, Mao Q, Zhang H, Han X
PloS one 2021;16(12):e0261388
PloS one 2021;16(12):e0261388
Interactions between the ERK1/2 signaling pathway and PCAF play a key role in PE‑induced cardiomyocyte hypertrophy.
Mao Q, Wu S, Peng C, Peng B, Luo X, Huang L, Zhang H
Molecular medicine reports 2021 Sep;24(3)
Molecular medicine reports 2021 Sep;24(3)
Diosgenin exerts anti-tumor effects through inactivation of cAMP/PKA/CREB signaling pathway in colorectal cancer.
Li SY, Shang J, Mao XM, Fan R, Li HQ, Li RH, Shen DY
European journal of pharmacology 2021 Oct 5;908:174370
European journal of pharmacology 2021 Oct 5;908:174370
A novel SIRT6 activator ameliorates neuroinflammation and ischemic brain injury via EZH2/FOXC1 axis.
He T, Shang J, Gao C, Guan X, Chen Y, Zhu L, Zhang L, Zhang C, Zhang J, Pang T
Acta pharmaceutica Sinica. B 2021 Mar;11(3):708-726
Acta pharmaceutica Sinica. B 2021 Mar;11(3):708-726
PGC1α Promotes Cisplatin Resistance in Ovarian Cancer by Regulating the HSP70/HK2/VDAC1 Signaling Pathway.
Li Y, Kang J, Fu J, Luo H, Liu Y, Li Y, Sun L
International journal of molecular sciences 2021 Mar 3;22(5)
International journal of molecular sciences 2021 Mar 3;22(5)
Overexpression of retinoid X receptor beta provides protection against oxidized low-density lipoprotein-induced inflammation via regulating PGC1α-dependent mitochondrial homeostasis in endothelial cells.
Zeng Y, Yan Wang C, Xu J, Le Xu X
Biochemical pharmacology 2021 Jun;188:114559
Biochemical pharmacology 2021 Jun;188:114559
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Jia P, Wu N, Yang H, Guo Y, Guo X, Sun Y
Translational research : the journal of laboratory and clinical medicine 2021 Jul;233:47-61
Translational research : the journal of laboratory and clinical medicine 2021 Jul;233:47-61
Betulinic acid attenuated bleomycin-induced pulmonary fibrosis by effectively intervening Wnt/β-catenin signaling.
Li X, Liu X, Deng R, Gao S, Jiang Q, Liu R, Li H, Miao Y, Zhai Y, Zhang S, Wang Z, Ren Y, Ning W, Zhou H, Yang C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Jan;81:153428
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Jan;81:153428
USP15 participates in DBP-induced testicular oxidative stress injury through regulating the Keap1/Nrf2 signaling pathway.
Zhang L, Gao X, Qin Z, Shi X, Xu K, Wang S, Tang M, Wang W, Gao S, Zuo L, Zhang L, Zhang W
The Science of the total environment 2021 Aug 20;783:146898
The Science of the total environment 2021 Aug 20;783:146898
Pygo1 regulates pathological cardiac hypertrophy via a β-catenin-dependent mechanism.
Lin L, Xu W, Li Y, Zhu P, Yuan W, Liu M, Shi Y, Chen Y, Liang J, Chen J, Yang B, Cai W, Wen Y, Zhu X, Peng X, Zhou Z, Mo X, Wan Y, Yuan H, Li F, Ye X, Jiang Z, Wang Y, Zhuang J, Fan X, Wu X
American journal of physiology. Heart and circulatory physiology 2021 Apr 1;320(4):H1634-H1645
American journal of physiology. Heart and circulatory physiology 2021 Apr 1;320(4):H1634-H1645
5-Azacytidine-Induced Cardiomyocyte Differentiation of Very Small Embryonic-Like Stem Cells.
Sun X, Li H, Zhu Y, Xu P, Zuo Q, Li B, Gu X
Stem cells international 2020;2020:5162350
Stem cells international 2020;2020:5162350
Prognostic Significance and Related Mechanisms of Hexokinase 1 in Ovarian Cancer.
Li Y, Tian H, Luo H, Fu J, Jiao Y, Li Y
OncoTargets and therapy 2020;13:11583-11594
OncoTargets and therapy 2020;13:11583-11594
Evaluation of toxicity of halloysite nanotubes and multi-walled carbon nanotubes to endothelial cells in vitro and blood vessels in vivo.
Wu B, Jiang M, Liu X, Huang C, Gu Z, Cao Y
Nanotoxicology 2020 Oct;14(8):1017-1038
Nanotoxicology 2020 Oct;14(8):1017-1038
USP22 promotes proliferation in renal cell carcinoma by stabilizing survivin.
Lin Y, Zhong H, Sun B, Peng Y, Lu F, Chen M, Zhu M, Huang J
Oncology letters 2020 Nov;20(5):246
Oncology letters 2020 Nov;20(5):246
Identification of miR-515-3p and its targets, vimentin and MMP3, as a key regulatory mechanism in esophageal cancer metastasis: functional and clinical significance.
Hu HF, Xu WW, Zhang WX, Yan X, Li YJ, Li B, He QY
Signal transduction and targeted therapy 2020 Nov 27;5(1):271
Signal transduction and targeted therapy 2020 Nov 27;5(1):271
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Sun J, Chu S, Lu M, Pan Q, Li D, Zheng S, Ma L
Experimental lung research 2020 May-Aug;46(6):163-173
Experimental lung research 2020 May-Aug;46(6):163-173
Ginsenoside Rg3 promotes regression from hepatic fibrosis through reducing inflammation-mediated autophagy signaling pathway.
Liu X, Mi X, Wang Z, Zhang M, Hou J, Jiang S, Wang Y, Chen C, Li W
Cell death & disease 2020 Jun 12;11(6):454
Cell death & disease 2020 Jun 12;11(6):454
AMPK decreases ERK1/2 activity and cancer cell sensitivity to nutrition deprivation by mediating a positive feedback loop involving eEF2K.
Tong S, Zhou T, Meng Y, Xu D, Chen J
Oncology letters 2020 Jul;20(1):61-66
Oncology letters 2020 Jul;20(1):61-66
Fucoxanthin inhibits hepatic oxidative stress, inflammation, and fibrosis in diet-induced nonalcoholic steatohepatitis model mice.
Takatani N, Kono Y, Beppu F, Okamatsu-Ogura Y, Yamano Y, Miyashita K, Hosokawa M
Biochemical and biophysical research communications 2020 Jul 23;528(2):305-310
Biochemical and biophysical research communications 2020 Jul 23;528(2):305-310
Moderate-Intensity Continuous Training Improves FGF21 and KLB Expression in Obese Mice.
Xiong Y, Chen Y, Liu Y, Zhang B
Biochemistry. Biokhimiia 2020 Aug;85(8):938-946
Biochemistry. Biokhimiia 2020 Aug;85(8):938-946
CFIm25-regulated lncRNA acv3UTR promotes gastric tumorigenesis via miR-590-5p/YAP1 axis.
Liu K, Wang BJ, Han W, Chi CH, Gu C, Wang Y, Fu X, Huang W, Liu Z, Song X
Oncogene 2020 Apr;39(15):3075-3088
Oncogene 2020 Apr;39(15):3075-3088
Therapeutic Effects of Human Urine-Derived Stem Cells in a Rat Model of Cisplatin-Induced Acute Kidney Injury In Vivo and In Vitro.
Sun B, Luo X, Yang C, Liu P, Yang Y, Dong X, Yang Z, Xu J, Zhang Y, Li L
Stem cells international 2019;2019:8035076
Stem cells international 2019;2019:8035076
miR-30a-3p Targets MAD2L1 and Regulates Proliferation of Gastric Cancer Cells.
Wang Y, Wang F, He J, Du J, Zhang H, Shi H, Chen Y, Wei Y, Xue W, Yan J, Feng Y, Gao Y, Li D, Han J, Zhang J
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OncoTargets and therapy 2019;12:11313-11324
MicroRNA-92b-3p suppresses angiotensin II-induced cardiomyocyte hypertrophy via targeting HAND2.
Yu XJ, Huang YQ, Shan ZX, Zhu JN, Hu ZQ, Huang L, Feng YQ, Geng QS
Life sciences 2019 Sep 1;232:116635
Life sciences 2019 Sep 1;232:116635
CUDC-907 displays potent antitumor activity against human pancreatic adenocarcinoma in vitro and in vivo through inhibition of HDAC6 to downregulate c-Myc expression.
Fu XH, Zhang X, Yang H, Xu XW, Hu ZL, Yan J, Zheng XL, Wei RR, Zhang ZQ, Tang SR, Geng MY, Huang X
Acta pharmacologica Sinica 2019 May;40(5):677-688
Acta pharmacologica Sinica 2019 May;40(5):677-688
FAM83D inhibits autophagy and promotes proliferation and invasion of ovarian cancer cells via PI3K/AKT/mTOR pathway.
Zhu H, Diao S, Lim V, Hu L, Hu J
Acta biochimica et biophysica Sinica 2019 May 23;51(5):509-516
Acta biochimica et biophysica Sinica 2019 May 23;51(5):509-516
lncRNA TUG1 Promotes Cisplatin Resistance by Regulating CCND2 via Epigenetically Silencing miR-194-5p in Bladder Cancer.
Yu G, Zhou H, Yao W, Meng L, Lang B
Molecular therapy. Nucleic acids 2019 Jun 7;16:257-271
Molecular therapy. Nucleic acids 2019 Jun 7;16:257-271
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Wang S, Zuo H, Jin J, Lv W, Xu Z, Fan Y, Zhang J, Zuo B
Cell death & disease 2019 Jun 26;10(7):505
Cell death & disease 2019 Jun 26;10(7):505
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Wang Q, Sun Y, Li T, Liu L, Zhao Y, Li L, Zhang L, Meng Y
Molecular medicine reports 2019 Jan;19(1):499-507
Molecular medicine reports 2019 Jan;19(1):499-507
Epigallocatechin-3-gallate inhibits angiotensin II-induced cardiomyocyte hypertrophy via regulating Hippo signaling pathway in H9c2 rat cardiomyocytes.
Ma Y, Hu Y, Wu J, Wen J, Li S, Zhang L, Zhang J, Li Y, Li J
Acta biochimica et biophysica Sinica 2019 Apr 1;51(4):422-430
Acta biochimica et biophysica Sinica 2019 Apr 1;51(4):422-430
Thioredoxin-interacting protein deficiency ameliorates kidney inflammation and fibrosis in mice with unilateral ureteral obstruction.
Wu M, Li R, Hou Y, Song S, Han W, Chen N, Du Y, Ren Y, Shi Y
Laboratory investigation; a journal of technical methods and pathology 2018 Sep;98(9):1211-1224
Laboratory investigation; a journal of technical methods and pathology 2018 Sep;98(9):1211-1224
Gemin5 plays a role in unassembled-U1 snRNA disposal in SMN-deficient cells.
Jiang D, Zou X, Zhang C, Chen J, Li Z, Wang Y, Deng Z, Wang L, Chen S
FEBS letters 2018 Apr;592(8):1400-1411
FEBS letters 2018 Apr;592(8):1400-1411
Dihydroartemisinin inhibits the viability of cervical cancer cells by upregulating caveolin 1 and mitochondrial carrier homolog 2: Involvement of p53 activation and NAD(P)H:quinone oxidoreductase 1 downregulation.
Zhang T, Hu Y, Wang T, Cai P
International journal of molecular medicine 2017 Jul;40(1):21-30
International journal of molecular medicine 2017 Jul;40(1):21-30
L-PGDS Mediates Vagus Nerve Stimulation-Induced Neuroprotection in a Rat Model of Ischemic Stroke by Suppressing the Apoptotic Response.
Zhang L, Ma J, Jin X, Jia G, Jiang Y, Li C
Neurochemical research 2017 Feb;42(2):644-655
Neurochemical research 2017 Feb;42(2):644-655
Overexpression of TRIB3 promotes angiogenesis in human gastric cancer.
Dong S, Xia J, Wang H, Sun L, Wu Z, Bin J, Liao Y, Li N, Liao W
Oncology reports 2016 Oct;36(4):2339-48
Oncology reports 2016 Oct;36(4):2339-48
Loss of Mouse P2Y6 Nucleotide Receptor Is Associated with Physiological Macrocardia and Amplified Pathological Cardiac Hypertrophy.
Clouet S, Di Pietrantonio L, Daskalopoulos EP, Esfahani H, Horckmans M, Vanorlé M, Lemaire A, Balligand JL, Beauloye C, Boeynaems JM, Communi D
The Journal of biological chemistry 2016 Jul 22;291(30):15841-52
The Journal of biological chemistry 2016 Jul 22;291(30):15841-52
Vinexin β Interacts with Hepatitis C Virus NS5A, Modulating Its Hyperphosphorylation To Regulate Viral Propagation.
Xiong W, Yang J, Wang M, Wang H, Rao Z, Zhong C, Xin X, Mo L, Yu S, Shen C, Zheng C
Journal of virology 2015 Jul;89(14):7385-400
Journal of virology 2015 Jul;89(14):7385-400
Transgenic mice overexpressing glia maturation factor-β, an oxidative stress inducible gene, show premature aging due to Zmpste24 down-regulation.
Imai R, Asai K, Hanai J, Takenaka M
Aging 2015 Jul;7(7):486-99
Aging 2015 Jul;7(7):486-99
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Vattepu R, Yadav R, Beck MR
Protein science : a publication of the Protein Society 2015 Jan;24(1):70-80
Protein science : a publication of the Protein Society 2015 Jan;24(1):70-80
DEAD-box RNA helicase DDX3X inhibits DENV replication via regulating type one interferon pathway.
Li G, Feng T, Pan W, Shi X, Dai J
Biochemical and biophysical research communications 2015 Jan 2;456(1):327-32
Biochemical and biophysical research communications 2015 Jan 2;456(1):327-32
Oncogenic miR-17/20a Forms a Positive Feed-forward Loop with the p53 Kinase DAPK3 to Promote Tumorigenesis.
Cai Z, Cao R, Zhang K, Xue Y, Zhang C, Zhou Y, Zhou J, Sun H, Fu XD
The Journal of biological chemistry 2015 Aug 7;290(32):19967-75
The Journal of biological chemistry 2015 Aug 7;290(32):19967-75
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- rat skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 23660-1-AP( ACTA1 Antibody) at dilution of 1:4000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Alpha Actin antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human Alpha Actin. This antibody recognizes human, mouse, rat antigen. The Alpha Actin antibody has been validated for the following applications: ELISA, WB, IHC, IF analysis.