Antibody data
- Antibody Data
- Antigen structure
- References [212]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
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Validation data
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- Product number
- 23660-1-AP - Provider product page

- Provider
- Proteintech Group
- Product name
- Alpha Actin antibody
- Antibody type
- Polyclonal
- Description
- Alpha Actin antibody (Cat. #23660-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references 18F-FDG-PET/CT-negative gastric cancer employs glutamine-based gluconeogenesis and fatty acid oxidation to support tumor growth.
Astragalus Polysaccharide Alleviated Septic Associated Acute Kidney Injury Through Dual Mechanisms of RIPK1-Dependent Necroptosis and Autophagy in Macrophage.
Txnrd2 loss in skeletal muscle causes muscle atrophy and drives leanness and obesity resistance.
Inhibition of PD-L1 in tubular epithelial cells attenuates renal fibrosis by suppressing TGFβR1 and FZD6 signaling.
RBM8A confers oxaliplatin resistance in gastric cancer by maintaining EGFR mRNA stability.
Activation of the integrated stress response contributes to developmental delay and seizures caused by mitochondrial prolyl-tRNA synthetase (PARS2) deficiency.
LDL receptor affects the skeletal muscle and bone microstructure of female mouse through the Wnt/β-catenin signaling pathway.
OLFM4 mediating ischemia/reperfusion-induced kidney injury by regulating renal tubular epithelial cells ferroptosis via GPX4.
CLEC11A-Driven Molecular Mechanisms in Intervertebral Disc Degeneration: A Comprehensive Multi-Omics Study.
LEDGF Binds H3R17me2a Promoting De Novo Nucleotide Biosynthesis in SETD2 Mutant Clear Cell Renal Cell Carcinoma.
Zingerone treats postmenopausal osteoporosis via increased ferroptosis sensitivity by p53-mediated regulation of SAT1 and GPX4 expression.
A novel mouse model for LAMA2-related muscular dystrophy with analysis of molecular pathogenesis and clinical phenotype.
Ero1a, the most strongly hypoxia-induced protein in PASMCs, promotes the development of hypoxia- and monocrotaline-induced pulmonary hypertension in rats.
Targeting GPX2 to disrupt lipid homeostasis and enhance cisplatin sensitivity in diffuse gastric cancer.
ALDH2 inhibits angiogenesis in esophageal squamous cell carcinoma by suppressing the NOTCH1/PI3K/Akt signaling pathway.
MDMX reprograms glycolysis of hepatocellular carcinoma via 14-3-3γ/FOXO1.
Vasostatin-2 attenuates injury-induced neointimal hyperplasia through the ACE2/MasR/PPARγ/NR1D1/Gas1 axis.
Oxaloacetate stimulates phosphorylation of epidermal growth factor receptor in epithelial cells in vitro.
EFNA2 Mediates Stiffness-Regulated Hypopharyngeal Cancer Progression.
Inhibition of ULK1 attenuates ferroptosis-mediated cardiac hypertrophy via HMGA2/METTL14/SLC7A11 axis in mice.
Sacubitril/valsartan attenuated myocardial inflammation, fibrosis, apoptosis and promoted autophagy in doxorubicin-induced cardiotoxicity mice via regulating the AMPKα-mTORC1 signaling pathway.
Iron Drives Eosinophil Differentiation in Allergic Airway Inflammation Through Mitochondrial Metabolic Adaptation.
Colon cancer-cell-specific drug delivery by gemcitabine conjugated with peptide chain targeting ENO1.
Targeted Degradation of Bromodomain-Containing Protein 4 Enabled by Reactive Oxygen Species-Activatable NanoPROTACs as an Efficient Strategy to Reverse Liver Fibrosis in Chronic Liver Injury.
Prexasertib exerts a synergistic effect on the antitumor activity of Lenvatinib through ALOX15-mediated ferroptosis in hepatocellular carcinoma.
Intestinal microbiota affects the progression of colorectal cancer by participating in the host intestinal arginine catabolism.
Gestational arsenite exposure alters maternal postpartum heart size and induces Ca(2+)-handling dysregulation in cardiomyocytes.
MyoMed205 Counteracts Titin Hyperphosphorylation and the Expression of Contraction-Regulating Proteins in a Rat Model of HFpEF.
Heshuxiaoji pill suppresses steatohepatitis and fibrosis by regulating the AngII-BACH1 mediated vasoconstriction.
Dip2a regulates stress susceptibility in the basolateral amygdala.
Targeting METTL3 protein by proteolysis-targeting chimeras: A novel therapeutic approach for acute myeloid leukemia.
FBP1 as a key regulator of focal adhesion kinase-mediated hepatic stellate cell activation: Multi-omics and experimental validation.
CuOTeDsP nanotherapeutics enhance cuproptosis-mediated immunotherapy by modulating cholesterol metabolism in bladder cancer.
ATM/ATR-Mediated DNA Damage Response Facilitates SARS-CoV-2 Spike Protein-Induced Syncytium Formation.
Diagnostic and prognostic potential of FBXO8 expression in kidney renal clear cell carcinoma and its regulation of renal adenocarcinoma cells.
Betulinic Acid Inhibits Glioma Progression by Inducing Ferroptosis Through the PI3K/Akt and NRF2/HO-1 Pathways.
PTPN9 promotes melanoma progression by regulating the ferroptosis pathway.
Uncovering endothelial to mesenchymal transition drivers in atherosclerosis via multi-omics analysis.
Membrane-Associated RING-CH-Type Finger 6 Protects against Hypertension-Induced Cardiac Remodeling by Suppressing Cardiomyocyte Ferroptosis Through the Degradation of ACSL4.
USP36 suppresses breast cancer cell ferroptosis by regulating the ubiquitination and stability of KIF2C.
USP18 promotes ferroptosis in lipopolysaccharide-induced human kidney organoids by stabilizing STING1.
AMPK regulates ARF1 localization to membrane contact sites to facilitate fatty acid transfer between lipid droplets and mitochondria.
Nuclear accumulation of YTHDF1 regulates mRNA splicing in the DNA damage response.
PMEPA1 promotes gastric cancer cell proliferation by regulating the ubiquitin-mediated degradation of 14-3-3σ and promoting cell cycle progression.
Identification of DNA methylation-regulated WEE1 with potential implications in prognosis and immunotherapy for low-grade glioma.
METTL3 Inhibition Suppresses Cell Growth and Survival in Colorectal Cancer via ASNS Downregulation.
IMPC-based screening revealed that ROBO1 can regulate osteoporosis by inhibiting osteogenic differentiation.
Deubiquitinating Enzyme USP19 Regulates Ferroptosis and Mitochondrial Damage in SH-SY5Y Cells by Targeting the NOX4 Protein.
The metabolic activation of and platelet response to vicagrel vary with P-glycoprotein deficiency, rather than P-glycoprotein inhibition, in mice.
The FAcilitates Chromatin Transcription complex regulates the ratio of glycolysis to oxidative phosphorylation in neural stem cells.
FBXO2 promotes the progression of papillary thyroid carcinoma through the p53 pathway.
Inflammatory Signaling via PEIZO1 Engages and Enhances the LPS-Mediated Apoptosis during Clinical Mastitis.
Strategic targeting of miR-183 and β-catenin to enhance BMSC stemness in age-related osteoporosis therapy.
Targeting PNPO to suppress tumor growth via inhibiting autophagic flux and to reverse paclitaxel resistance in ovarian cancer.
MicroRNA hsa-let-7e-5p in hUC-MSC-EVs alleviates oral mucositis by targeting TAB2.
Tumor cell-intrinsic Piezo2 drives radioresistance by impairing CD8+ T cell stemness maintenance.
Construction of an autophagy-related genes risk model as predicting prognosis: BAG1 suppresses growth of clear cell renal cell carcinoma.
eIF6 deficiency regulates gut microbiota, decreases systemic inflammation, and alleviates atherosclerosis.
Leukemia inhibitory factor protects against experimental periodontitis through immuno-modulations of both macrophages and periodontal ligament fibroblasts.
HRD1 reduction promotes cholesterol-induced vascular smooth muscle cell phenotypic change via endoplasmic reticulum stress.
The PRMT6/STAT1/ACSL1 axis promotes ferroptosis in diabetic nephropathy.
Luteolin protects against myocardial ischemia/reperfusion injury by reducing oxidative stress and apoptosis through the p53 pathway.
CCDC50 mediates the clearance of protein aggregates to prevent cellular proteotoxicity.
Angiotensin II depends on hippo/YAP signaling to reprogram angiogenesis and promote liver fibrosis.
Comparative proteomic analysis between tumor tissues and intratumoral exosomes from lung adenocarcinoma patients identifies PAFAH1B3 as an exosomal protein key for initiating metastasis in lung adenocarcinoma.
MDM4 inhibits ferroptosis in p53 mutant colon cancer via regulating TRIM21/GPX4 expression.
Hepatocyte growth factor promotes melanoma metastasis through ubiquitin-specific peptidase 22-mediated integrins upregulation.
Stevioside Ameliorates Palmitic Acid-Induced Abnormal Glucose Uptake via the PDK4/AMPK/TBC1D1 Pathway in C2C12 Myotubes.
Intravitreal Delivery of rAAV2-hSyn-hRS1 Results in Retinal Ganglion Cell-Specific Gene Expression and Retinal Improvement in the Rs1-KO Mouse.
The Jagged-1/Notch1 Signaling Pathway Promotes the Construction of Tissue-Engineered Heart Valves.
Myricanol improves metabolic profiles in dexamethasone induced lipid and protein metabolism disorders in mice.
QDPR deficiency drives immune suppression in pancreatic cancer.
Effects of Pemafibrate on Reducing Oxidative Stress and Augmenting Angiogenesis in Ischemic Limb Tissue.
High fat diet ameliorates mitochondrial cardiomyopathy in CHCHD10 mutant mice.
The regulation of MFG-E8 on the mitophagy in diabetic sarcopenia via the HSPA1L-Parkin pathway and the effect of D-pinitol.
ARID1A loss promotes RNA editing of CDK13 in an ADAR1-dependent manner.
Lumbrokinase Extracted from Earthworms Synergizes with Bevacizumab and Chemotherapeutics in Treating Non-Small Cell Lung Cancer by Targeted Inactivation of BPTF/VEGF and NF-κB/COX-2 Signaling.
d-mannose targets PD-1 to lysosomal degradation and enhances T cell-mediated anti-tumor immunity.
Accumulation of γδT cells in the decidua is promoted by RANKL which upregulates ICAM-1 via NF-κB.
AN698/40746067 suppresses bone marrow adiposity to ameliorate hyperlipidemia-induced osteoporosis through targeted inhibition of ENTR1.
H3K27ac acts as a molecular switch for doxorubicin-induced activation of cardiotoxic genes.
Shenqu xiaoshi oral solution enhances digestive function and stabilizes the gastrointestinal microbiota of juvenile rats with infantile anorexia.
MDM4 was associated with poor prognosis and tumor-immune infiltration of cancers.
Overcoming therapeutic resistance in oncolytic herpes virotherapy by targeting IGF2BP3-induced NETosis in malignant glioma.
Identification and experimental validation of Stearoyl-CoA desaturase is a new drug therapeutic target for osteosarcoma.
TRIM56 protects against nonalcoholic fatty liver disease by promoting the degradation of fatty acid synthase.
Hesperetin promotes bladder cancer cells death via the PI3K/AKT pathway by network pharmacology and molecular docking.
AZD7762 induces CRBN dependent BAG3 degradation through ubiquitin-proteasome pathway.
AMPK/PGC-1α and p53 modulate VDAC1 expression mediated by reduced ATP level and metabolic oxidative stress in neuronal cells.
Endothelium-specific deletion of p62 causes organ fibrosis and cardiac dysfunction.
ADAR1 Promotes Invasion and Migration and Inhibits Ferroptosis via the FAK/AKT Pathway in Colorectal Cancer.
TRPM2 knockdown attenuates myocardial apoptosis and promotes autophagy in HFD/STZ-induced diabetic mice via regulating the MEK/ERK and mTORC1 signaling pathway.
Mesenchymal stem cells may alleviate angiotensin II-induced myocardial fibrosis and hypertrophy by upregulating SFRS3 expression.
Fibroblast growth factor 2 enhances BMSC stemness through ITGA2-dependent PI3K/AKT pathway activation.
Neuroinvasive virus utilizes a lipid droplet surface protein, perilipin2, to restrict apoptosis by decreasing Bcl-2 ubiquitination.
Zishen Qingre Lishi Huayu Recipe May Ameliorate the Symptoms of PCOS Model Rats via Alleviating Systemic and Ovarian Inflammation.
Nicotinamide protects against diabetic kidney disease through regulation of Sirt1.
Dietary sodium sulphate supplementation during mid-to-late gestation improves placental angiogenesis, bile acid metabolism, and serum amino acid concentrations of sows.
Accumulated β-catenin is associated with human atrial fibrosis and atrial fibrillation.
Antitumor effects of a Sb-rich polyoxometalate on non-small-cell lung cancer by inducing ferroptosis and apoptosis.
SGK3 deficiency in macrophages suppresses angiotensin II-induced cardiac remodeling via regulating Ndufa13-mediated mitochondrial oxidative stress.
USP36 regulates the proliferation, survival, and differentiation of hFOB1.19 osteoblast.
Heterozygous Gnaq deficiency enhances Ifi202b/IFI16 and NF-κB activation in endothelial cells and exacerbates lupus nephritis pathology.
Endothelial H(2)S-AMPK dysfunction upregulates the angiocrine factor PAI-1 and contributes to lung fibrosis.
Rapamycin protects Sertoli cells against BPA-induced autophagy disorders.
H(2)S-Releasing Versatile Montmorillonite Nanoformulation Trilogically Renovates the Gut Microenvironment for Inflammatory Bowel Disease Modulation.
Exercise training affects calcium ion transport by downregulating the CACNA2D1 protein to reduce hypertension-induced myocardial injury in mice.
Pharmacological Activation of Rev-erbα Attenuates Doxorubicin-Induced Cardiotoxicity by PGC-1α Signaling Pathway.
Sema3A Modified PDLSCs Exhibited Enhanced Osteogenic Capabilities and Stimulated Differentiation of Pre-Osteoblasts.
Effect of Tamoxifen on Proteome Expression during In Vitro Myogenesis in Murine Skeletal Muscle C(2)C(12) Cells.
Atorvastatin rescues vascular endothelial injury in hypertension by WWP2-mediated ubiquitination and degradation of ATP5A.
Melatonin alleviates depression-like behaviors and cognitive dysfunction in mice by regulating the circadian rhythm of AQP4 polarization.
Inhibition of Sirt2 Decreases ApoE Secretion in Astrocytes and Microglial Cells.
Depletion of PIEZO1 expression is accompanied by upregulating p53 signaling in mice with perioperative neurocognitive disorder.
ZSCAN4 interacts with PARP1 to promote DNA repair in mouse embryonic stem cells.
Human amnion-derived mesenchymal stem cells improve subclinical hypothyroidism by immunocompetence mediating apoptosis inhibition on thyroid cells in aged mice.
Integrated network pharmacology to investigate the mechanism of Salvia miltiorrhiza Bunge in the treatment of myocardial infarction.
CCDC127 regulates lipid droplet homeostasis by enhancing mitochondria-ER contacts.
NUAK1 promotes tumor metastasis through upregulating slug transcription in esophageal squamous cell carcinoma.
Crucial role of hsa-mir-503, hsa-mir-1247, and their validation in prostate cancer.
Active post-transcriptional regulation and ACLY-mediated acetyl-CoA synthesis as a pivotal target of Shuang-Huang-Sheng-Bai formula for lung adenocarcinoma treatment.
Down-regulation of WWP2 aggravates Type 2 diabetes mellitus-induced vascular endothelial injury through modulating ubiquitination and degradation of DDX3X.
SIRT2 Deficiency Aggravates Diet-Induced Nonalcoholic Fatty Liver Disease through Modulating Gut Microbiota and Metabolites.
ACTA1 H40Y mutant iPSC-derived skeletal myocytes display mitochondrial defects in an in vitro model of nemaline myopathy.
Rare sugar L-sorbose exerts antitumor activity by impairing glucose metabolism.
Inhibition of TLR4 Alleviates Heat Stroke-Induced Cardiomyocyte Injury by Down-Regulating Inflammation and Ferroptosis.
Gallocatechin Gallate Inhibits the Replication of Pseudorabies Virus via Suppressing the Entry and Release Stages in Its Replication Cycle.
Sleep Deprivation Promotes Endothelial Inflammation and Atherogenesis by Reducing Exosomal miR-182-5p.
The Valsa Mali effector Vm1G-1794 protects the aggregated MdEF-Tu from autophagic degradation to promote infection in apple.
5'-tiRNA-Gln inhibits hepatocellular carcinoma progression by repressing translation through the interaction with eukaryotic initiation factor 4A-I.
MFN2 deficiency affects calcium homeostasis in lung adenocarcinoma cells via downregulation of UCP4.
Aloe-emodin ameliorated MI-induced cardiac remodeling in mice via inhibiting TGF-β/SMAD signaling via up-regulating SMAD7.
Curcumol, a major terpenoid from Curcumae Rhizoma, attenuates human uterine leiomyoma cell development via the p38MAPK/NF-κB pathway.
CaMKK2 alleviates myocardial ischemia/reperfusion injury by inhibiting oxidative stress and inflammation via the action on the AMPK-AKT-GSK-3β/Nrf2 signaling cascade.
Nucleolus assembly impairment leads to two-cell transcriptional repression via NPM1-mediated PRC2 recruitment.
NCOA7 Regulates Growth and Metastasis of Clear Cell Renal Cell Carcinoma via MAPK/ERK Signaling Pathway.
HMOX1 Promotes Ferroptosis Induced by Erastin in Lens Epithelial Cell through Modulates Fe(2+) Production.
Metabolomic and transcriptomic studies of improvements in myocardial infarction due to Pycr1 deletion.
CMTM6 overexpression confers trastuzumab resistance in HER2-positive breast cancer.
The protective effect of inhibiting mitochondrial fission on the juvenile rat brain following PTZ kindling through inhibiting the BCL2L13/LC3 mitophagy pathway.
G9a inhibition promotes the formation of pacemaker-like cells by reducing the enrichment of H3K9me2 in the HCN4 promoter region.
Lenvatinib inhibits intrahepatic cholangiocarcinoma via Gadd45a-mediated cell cycle arrest.
SIRT3 promotes metabolic maturation of human iPSC-derived cardiomyocytes via OPA1-controlled mitochondrial dynamics.
LOC102549726/miR-760-3p network is involved in the progression of ISO-induced pathological cardiomyocyte hypertrophy via endoplasmic reticulum stress.
The effect of cold exposure on the levels of glucocorticoids, 11-hydroxysteroid dehydrogenase 2, and placental vascularization in a rat model.
miR-146a-5p Modulates Adult Hippocampal Neurogenesis Deficits Through Klf4/p-Stat3 Signaling in APP/PS1 Mice.
Orexin-A Reverse Bone Mass Loss Induced by Chronic Intermittent Hypoxia Through OX1R-Nrf2/HIF-1α Pathway.
Matrine, a potential c-Myc inhibitor, suppresses ribosome biogenesis and nucleotide metabolism in myeloid leukemia.
ITGB5 promotes innate radiation resistance in pancreatic adenocarcinoma by promoting DNA damage repair and the MEK/ERK signaling pathway.
DJ-1 promotes osteosarcoma progression through activating CDK4/RB/E2F1 signaling pathway.
Multi-Omics Analysis of MCM2 as a Promising Biomarker in Pan-Cancer.
Targeting p65 to inhibit Cas3 transcription by Onjisaponin B for radiation damage therapy in p65+/- mice.
Hace1 overexpression mitigates myocardial hypoxia/reoxygenation injury via the effects on Keap1/Nrf2 pathway.
CAMSAP2 promotes colorectal cancer cell migration and invasion through activation of JNK/c-Jun/MMP-1 signaling pathway.
LINC00514 facilitates cell proliferation, migration, invasion, and epithelial-mesenchymal transition in non-small cell lung cancer by acting on the Wnt/β-catenin signaling pathway.
Scutellarein protects against cardiac hypertrophy via suppressing TRAF2/NF-κB signaling pathway.
Chlorine disinfection elevates the toxicity of polystyrene microplastics to human cells by inducing mitochondria-dependent apoptosis.
TXNIP knockout improves cardiac function after myocardial infarction by promoting angiogenesis and reducing cardiomyocyte apoptosis.
Erectile dysfunction in hypospadiac male adult rats induced by maternal exposure to di-n-butyl phthalate.
LncRNA BACE1-AS promotes the progression of osteosarcoma through miR-762/SOX7 axis.
ZC3H4 promotes pulmonary fibrosis via an ER stress-related positive feedback loop.
BUB1B (BUB1 Mitotic Checkpoint Serine/Threonine Kinase B) promotes lung adenocarcinoma by interacting with Zinc Finger Protein ZNF143 and regulating glycolysis.
Design, synthesis and biological evaluation of novel 1,3,4,9-tetrahydropyrano[3,4-b]indoles as potential treatment of triple negative breast cancer by suppressing PI3K/AKT/mTOR pathway.
The RNA polymerase of cytoplasmically replicating Zika virus binds with chromatin DNA in nuclei and regulates host gene transcription.
Functional investigation of SLC1A2 variants associated with epilepsy.
RSL3 triggers glioma stem cell differentiation via the Tgm2/AKT/ID1 signaling axis.
Mitochondrial dysfunction by TFAM depletion disrupts self-renewal and lineage differentiation of human PSCs by affecting cell proliferation and YAP response.
Luteolin alleviates cognitive impairment in Alzheimer's disease mouse model via inhibiting endoplasmic reticulum stress-dependent neuroinflammation.
NAP1L5 Promotes Nucleolar Hypertrophy and Is Required for Translation Activation During Cardiomyocyte Hypertrophy.
JNK signaling-dependent regulation of histone acetylation are involved in anacardic acid alleviates cardiomyocyte hypertrophy induced by phenylephrine.
Interactions between the ERK1/2 signaling pathway and PCAF play a key role in PE‑induced cardiomyocyte hypertrophy.
Diosgenin exerts anti-tumor effects through inactivation of cAMP/PKA/CREB signaling pathway in colorectal cancer.
A novel SIRT6 activator ameliorates neuroinflammation and ischemic brain injury via EZH2/FOXC1 axis.
PGC1α Promotes Cisplatin Resistance in Ovarian Cancer by Regulating the HSP70/HK2/VDAC1 Signaling Pathway.
Overexpression of retinoid X receptor beta provides protection against oxidized low-density lipoprotein-induced inflammation via regulating PGC1α-dependent mitochondrial homeostasis in endothelial cells.
Different roles of BAG3 in cardiac physiological hypertrophy and pathological remodeling.
Betulinic acid attenuated bleomycin-induced pulmonary fibrosis by effectively intervening Wnt/β-catenin signaling.
USP15 participates in DBP-induced testicular oxidative stress injury through regulating the Keap1/Nrf2 signaling pathway.
Pygo1 regulates pathological cardiac hypertrophy via a β-catenin-dependent mechanism.
5-Azacytidine-Induced Cardiomyocyte Differentiation of Very Small Embryonic-Like Stem Cells.
Prognostic Significance and Related Mechanisms of Hexokinase 1 in Ovarian Cancer.
Evaluation of toxicity of halloysite nanotubes and multi-walled carbon nanotubes to endothelial cells in vitro and blood vessels in vivo.
USP22 promotes proliferation in renal cell carcinoma by stabilizing survivin.
Identification of miR-515-3p and its targets, vimentin and MMP3, as a key regulatory mechanism in esophageal cancer metastasis: functional and clinical significance.
The roles of dipeptidyl peptidase-4 and its inhibitors in the regulation of airway epithelial-mesenchymal transition.
Ginsenoside Rg3 promotes regression from hepatic fibrosis through reducing inflammation-mediated autophagy signaling pathway.
AMPK decreases ERK1/2 activity and cancer cell sensitivity to nutrition deprivation by mediating a positive feedback loop involving eEF2K.
Fucoxanthin inhibits hepatic oxidative stress, inflammation, and fibrosis in diet-induced nonalcoholic steatohepatitis model mice.
LINC00365-SCGB2A1 axis inhibits the viability of breast cancer through targeting NF-κB signaling.
Moderate-Intensity Continuous Training Improves FGF21 and KLB Expression in Obese Mice.
CFIm25-regulated lncRNA acv3UTR promotes gastric tumorigenesis via miR-590-5p/YAP1 axis.
Therapeutic Effects of Human Urine-Derived Stem Cells in a Rat Model of Cisplatin-Induced Acute Kidney Injury In Vivo and In Vitro.
Hepatitis B Virus X Protein-Induced RORγ Expression to Promote the Migration and Proliferation of Hepatocellular Carcinoma.
miR-30a-3p Targets MAD2L1 and Regulates Proliferation of Gastric Cancer Cells.
MicroRNA-92b-3p suppresses angiotensin II-induced cardiomyocyte hypertrophy via targeting HAND2.
CUDC-907 displays potent antitumor activity against human pancreatic adenocarcinoma in vitro and in vivo through inhibition of HDAC6 to downregulate c-Myc expression.
FAM83D inhibits autophagy and promotes proliferation and invasion of ovarian cancer cells via PI3K/AKT/mTOR pathway.
lncRNA TUG1 Promotes Cisplatin Resistance by Regulating CCND2 via Epigenetically Silencing miR-194-5p in Bladder Cancer.
Long noncoding RNA Neat1 modulates myogenesis by recruiting Ezh2.
Function of BRD4 in the pathogenesis of high glucose‑induced cardiac hypertrophy.
Epigallocatechin-3-gallate inhibits angiotensin II-induced cardiomyocyte hypertrophy via regulating Hippo signaling pathway in H9c2 rat cardiomyocytes.
Thioredoxin-interacting protein deficiency ameliorates kidney inflammation and fibrosis in mice with unilateral ureteral obstruction.
Gemin5 plays a role in unassembled-U1 snRNA disposal in SMN-deficient cells.
Dihydroartemisinin inhibits the viability of cervical cancer cells by upregulating caveolin 1 and mitochondrial carrier homolog 2: Involvement of p53 activation and NAD(P)H:quinone oxidoreductase 1 downregulation.
L-PGDS Mediates Vagus Nerve Stimulation-Induced Neuroprotection in a Rat Model of Ischemic Stroke by Suppressing the Apoptotic Response.
Overexpression of TRIB3 promotes angiogenesis in human gastric cancer.
Loss of Mouse P2Y6 Nucleotide Receptor Is Associated with Physiological Macrocardia and Amplified Pathological Cardiac Hypertrophy.
Vinexin β Interacts with Hepatitis C Virus NS5A, Modulating Its Hyperphosphorylation To Regulate Viral Propagation.
Transgenic mice overexpressing glia maturation factor-β, an oxidative stress inducible gene, show premature aging due to Zmpste24 down-regulation.
Actin-induced dimerization of palladin promotes actin-bundling.
DEAD-box RNA helicase DDX3X inhibits DENV replication via regulating type one interferon pathway.
Oncogenic miR-17/20a Forms a Positive Feed-forward Loop with the p53 Kinase DAPK3 to Promote Tumorigenesis.
Liu J, Xia M, Zhao Z, Gao T, Qu Y, Wang Q, Liu X, Du J, Han S, Yang S, Wei M, Jin X, Wang Y
Cell death & disease 2026 Mar 26;17(1)
Cell death & disease 2026 Mar 26;17(1)
Astragalus Polysaccharide Alleviated Septic Associated Acute Kidney Injury Through Dual Mechanisms of RIPK1-Dependent Necroptosis and Autophagy in Macrophage.
Wang L, Zhang W, Wang Z, Zhang W, Zhang L, Li J, Mao Z, Zhang J, Liang T, Ge R, Zhang Y, Yan C, Zhang J, Liang T
Phytotherapy research : PTR 2026 Mar 17;
Phytotherapy research : PTR 2026 Mar 17;
Txnrd2 loss in skeletal muscle causes muscle atrophy and drives leanness and obesity resistance.
Kiermayer C, Erdelen R, Schriever SC, Böhm R, Prehn C, Artati A, Kleinert M, Miller M, Dyar KA, Schmid RM, Pfluger PT, Adamski J, Brielmeier M
Redox biology 2026 Jun;93:104165
Redox biology 2026 Jun;93:104165
Inhibition of PD-L1 in tubular epithelial cells attenuates renal fibrosis by suppressing TGFβR1 and FZD6 signaling.
Ahui S, Xufei X, Wangshu W, Bingru Z, Minzhou W, Jiayue L, Wenkai H, Kewei X, Leyi G
International immunopharmacology 2026 Jun 15;179:116621
International immunopharmacology 2026 Jun 15;179:116621
RBM8A confers oxaliplatin resistance in gastric cancer by maintaining EGFR mRNA stability.
Ma Y, Xiang Y, Yang M, Zhu Y, Pan Y, Zhang N, Fu X, Jiang P, Pan Y, Wu H, Yan Q, Li W, Tao H, Mao S, Tao Y, Li J, Su L, Gao G, An F, Wang Z, Xu G
Oncogene 2026 Jan;45(2):339-351
Oncogene 2026 Jan;45(2):339-351
Activation of the integrated stress response contributes to developmental delay and seizures caused by mitochondrial prolyl-tRNA synthetase (PARS2) deficiency.
Xu M, Liu Y, Ma R, Fan W, Duan J, Deng H, Ma Y, Ge W
Redox biology 2026 Feb;89:103966
Redox biology 2026 Feb;89:103966
LDL receptor affects the skeletal muscle and bone microstructure of female mouse through the Wnt/β-catenin signaling pathway.
Hu Y, Liu H, Zhao C, Shi P, Lu M, Chen Y, Fang X, Huang L, Bai Z, Wang J, Li H
Journal of molecular histology 2026 Feb 19;57(2):81
Journal of molecular histology 2026 Feb 19;57(2):81
OLFM4 mediating ischemia/reperfusion-induced kidney injury by regulating renal tubular epithelial cells ferroptosis via GPX4.
Zhang Z, Wang Y, Mu Z, Zhao S, Zhang T, Zhang Z, Sun S, Bai M
Molecular biology reports 2026 Apr 25;53(1)
Molecular biology reports 2026 Apr 25;53(1)
CLEC11A-Driven Molecular Mechanisms in Intervertebral Disc Degeneration: A Comprehensive Multi-Omics Study.
Jiang N, Wang Q, Hu Z, Tian X
Journal of inflammation research 2025;18:1353-1375
Journal of inflammation research 2025;18:1353-1375
LEDGF Binds H3R17me2a Promoting De Novo Nucleotide Biosynthesis in SETD2 Mutant Clear Cell Renal Cell Carcinoma.
Zhang Y, Zhou Y, Zhang Y, Lv J, Shen Y, Zhang D, Liu B, Zhao W, Ju J, Zhu Q, Wang K, Feng N
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(35):e16809
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(35):e16809
Zingerone treats postmenopausal osteoporosis via increased ferroptosis sensitivity by p53-mediated regulation of SAT1 and GPX4 expression.
Li H, Cao F, Liu D, Tao L
Communications biology 2025 Sep 26;8(1):1367
Communications biology 2025 Sep 26;8(1):1367
A novel mouse model for LAMA2-related muscular dystrophy with analysis of molecular pathogenesis and clinical phenotype.
Tan D, Liu Y, Luo H, Shen Q, Long X, Xu L, Liu J, Zhong NA, Zhang H, Xiong H
eLife 2025 Sep 17;13
eLife 2025 Sep 17;13
Ero1a, the most strongly hypoxia-induced protein in PASMCs, promotes the development of hypoxia- and monocrotaline-induced pulmonary hypertension in rats.
Hao X, Li H, Zeng Q, Cheng Z, Jiang H
Life sciences 2025 Sep 1;376:123754
Life sciences 2025 Sep 1;376:123754
Targeting GPX2 to disrupt lipid homeostasis and enhance cisplatin sensitivity in diffuse gastric cancer.
Zhu Y, Ma Y, Li W, Pan Y, Wang Y, Ye Q, Pan Y, Xiang Y, Jiang P, Fang Y, Xu L, Liu N, Liu G, Wang Z, Xu G
Cell death discovery 2025 Oct 27;11(1):491
Cell death discovery 2025 Oct 27;11(1):491
ALDH2 inhibits angiogenesis in esophageal squamous cell carcinoma by suppressing the NOTCH1/PI3K/Akt signaling pathway.
Qiang J, Qiu T, Yang Y, Xu B, Huang H, Li X, Ma R, Lu Y, Dong Z
Cellular signalling 2025 Nov;135:112025
Cellular signalling 2025 Nov;135:112025
MDMX reprograms glycolysis of hepatocellular carcinoma via 14-3-3γ/FOXO1.
Chen H, Pan Q, Mao M, Lin W, Yan S, Liu J, Lin S, Li Q, Xue S, Xie Y, Ding L, Zheng D, You J, Huang Q
Cell death discovery 2025 Nov 7;11(1):509
Cell death discovery 2025 Nov 7;11(1):509
Vasostatin-2 attenuates injury-induced neointimal hyperplasia through the ACE2/MasR/PPARγ/NR1D1/Gas1 axis.
Chen Q, Liu J, Madonna R, Li F, Chen S, Li L, Wu X, Maimati Y, Ding F, Wang X, Shen Y, Zhang R, Shen W, Dai Y, Lu L, De Caterina R
Cardiovascular research 2025 Nov 22;121(14):2260-2277
Cardiovascular research 2025 Nov 22;121(14):2260-2277
Oxaloacetate stimulates phosphorylation of epidermal growth factor receptor in epithelial cells in vitro.
Kuang Y, Zhao Y, Miao Z, Xu Y, Yang Q
Growth factors (Chur, Switzerland) 2025 May;43(2):106-118
Growth factors (Chur, Switzerland) 2025 May;43(2):106-118
EFNA2 Mediates Stiffness-Regulated Hypopharyngeal Cancer Progression.
Hu S, Liu Y, Cheng M, Xu M, Liu H, Shan Y, Ni H, Xia T, Zhang Q, Zhang Z, You B
Clinical and experimental otorhinolaryngology 2025 May;18(2):188-199
Clinical and experimental otorhinolaryngology 2025 May;18(2):188-199
Inhibition of ULK1 attenuates ferroptosis-mediated cardiac hypertrophy via HMGA2/METTL14/SLC7A11 axis in mice.
Zhang M, Sha Y, Wang J, Qi H, Shi P, Liu Y, Jiang M, Ba L, Liu Y, Cao Y, Zhang Q, Sun H
European journal of pharmacology 2025 May 15;995:177416
European journal of pharmacology 2025 May 15;995:177416
Sacubitril/valsartan attenuated myocardial inflammation, fibrosis, apoptosis and promoted autophagy in doxorubicin-induced cardiotoxicity mice via regulating the AMPKα-mTORC1 signaling pathway.
Hu F, Yan S, Lin L, Qiu X, Lin X, Wang W
Molecular and cellular biochemistry 2025 Mar;480(3):1891-1908
Molecular and cellular biochemistry 2025 Mar;480(3):1891-1908
Iron Drives Eosinophil Differentiation in Allergic Airway Inflammation Through Mitochondrial Metabolic Adaptation.
Li F, Tang H, Wang Y, Wu Q, Dong L, Kitoko JZ, Huang J, Chen H, Jia R, Liu Z, Zhang C, Du X, Li W, Chen Z, Shen H, Ying S
Advanced healthcare materials 2025 Mar;14(7):e2405085
Advanced healthcare materials 2025 Mar;14(7):e2405085
Colon cancer-cell-specific drug delivery by gemcitabine conjugated with peptide chain targeting ENO1.
Hu X, Liu J, Wang Q, Hu Q, Sun H, Wang S, Zhao Y, Gu L, Shen J, Zhao Q, Sui F, Ma H
International journal of pharmaceutics 2025 Mar 30;673:125402
International journal of pharmaceutics 2025 Mar 30;673:125402
Targeted Degradation of Bromodomain-Containing Protein 4 Enabled by Reactive Oxygen Species-Activatable NanoPROTACs as an Efficient Strategy to Reverse Liver Fibrosis in Chronic Liver Injury.
Bi T, Liang P, Zhao Q, Wu J, Zhou Y, Xu Y, Fan X, Yang G, Sun Q, Ren W, Yang Y, Liu Z
Journal of medicinal chemistry 2025 Mar 27;68(6):6328-6338
Journal of medicinal chemistry 2025 Mar 27;68(6):6328-6338
Prexasertib exerts a synergistic effect on the antitumor activity of Lenvatinib through ALOX15-mediated ferroptosis in hepatocellular carcinoma.
Zhang S, Guan M, Ren T, Li N, Ding Q, Sun D, Zhu H
International immunopharmacology 2025 Mar 26;150:114278
International immunopharmacology 2025 Mar 26;150:114278
Intestinal microbiota affects the progression of colorectal cancer by participating in the host intestinal arginine catabolism.
Xu S, Zhang Y, Ding X, Yang Y, Gao J, Zou N, Lu L, He J
Cell reports 2025 Mar 25;44(3):115370
Cell reports 2025 Mar 25;44(3):115370
Gestational arsenite exposure alters maternal postpartum heart size and induces Ca(2+)-handling dysregulation in cardiomyocytes.
Taube N, Steiner M, Ebenebe-Kasonde OV, Kabir R, Garbus-Grant H, Alam El Din SM, Illingworth E, Wang N, Lin BL, Kohr MJ
American journal of physiology. Heart and circulatory physiology 2025 Mar 1;328(3):H460-H471
American journal of physiology. Heart and circulatory physiology 2025 Mar 1;328(3):H460-H471
MyoMed205 Counteracts Titin Hyperphosphorylation and the Expression of Contraction-Regulating Proteins in a Rat Model of HFpEF.
Vahle B, Schauer A, Augstein A, Jarabo MP, Friedrich J, Barthel P, Männel A, Mangner N, Labeit S, Bowen TS, Linke A, Adams V
Journal of cachexia, sarcopenia and muscle 2025 Jun;16(3):e13843
Journal of cachexia, sarcopenia and muscle 2025 Jun;16(3):e13843
Heshuxiaoji pill suppresses steatohepatitis and fibrosis by regulating the AngII-BACH1 mediated vasoconstriction.
Pu Y, Ren W, Gan Z, Wang S, Peng M, Yue R, Huang R
Journal of ethnopharmacology 2025 Jun 26;350:119989
Journal of ethnopharmacology 2025 Jun 26;350:119989
Dip2a regulates stress susceptibility in the basolateral amygdala.
Li J, He Z, Chai W, Tian M, Yu H, He X, Zhu X
Neural regeneration research 2025 Jun 1;20(6):1735-1748
Neural regeneration research 2025 Jun 1;20(6):1735-1748
Targeting METTL3 protein by proteolysis-targeting chimeras: A novel therapeutic approach for acute myeloid leukemia.
Nar R, Wu Z, Li Y, Smith A, Zhang Y, Wang J, Yu F, Gao S, Yu C, Huo Z, Zheng G, Qian Z
Genes & diseases 2025 Jul;12(4):101452
Genes & diseases 2025 Jul;12(4):101452
FBP1 as a key regulator of focal adhesion kinase-mediated hepatic stellate cell activation: Multi-omics and experimental validation.
Wu HY, Han L, Ran T, Sun Y, Zhang QX, Huang T, Zou GL, Zhang Y, Zhou YM, Lin GY, Chen SJ, Wang JL, Pan C, Lu F, Pu HF, Zhao XK
World journal of gastroenterology 2025 Jul 28;31(28):107361
World journal of gastroenterology 2025 Jul 28;31(28):107361
CuOTeDsP nanotherapeutics enhance cuproptosis-mediated immunotherapy by modulating cholesterol metabolism in bladder cancer.
Cai H, Xue P, Liu S, Ma Y, Zeng X, Yan S, Xu N
Journal of nanobiotechnology 2025 Jul 22;23(1):534
Journal of nanobiotechnology 2025 Jul 22;23(1):534
ATM/ATR-Mediated DNA Damage Response Facilitates SARS-CoV-2 Spike Protein-Induced Syncytium Formation.
Zhao X, Wei T, Hou Y, Wu Y, Zhou H, Meng J, Wang Q, Liu Y
Journal of medical virology 2025 Jan;97(1):e70137
Journal of medical virology 2025 Jan;97(1):e70137
Diagnostic and prognostic potential of FBXO8 expression in kidney renal clear cell carcinoma and its regulation of renal adenocarcinoma cells.
Luo Z, Wu X, Xie J, Tang H, Chen J, Ye D, Dou S, Chen S
Cancer genetics 2025 Jan;290-291:6-15
Cancer genetics 2025 Jan;290-291:6-15
Betulinic Acid Inhibits Glioma Progression by Inducing Ferroptosis Through the PI3K/Akt and NRF2/HO-1 Pathways.
Huang J, Li Q, Wang H, Zhang S, Zhou X, Huang F, Chen J, Xu L, Kang D
The journal of gene medicine 2025 Feb;27(2):e70011
The journal of gene medicine 2025 Feb;27(2):e70011
PTPN9 promotes melanoma progression by regulating the ferroptosis pathway.
Wang H, Qiao S, Huang L, Zhang Z, Wang J, Tian W
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Feb 28;39(4):e70394
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Feb 28;39(4):e70394
Uncovering endothelial to mesenchymal transition drivers in atherosclerosis via multi-omics analysis.
Huang Q, Gan Y, Zheng X, Yu Z, Huang Q, Huang M
BMC cardiovascular disorders 2025 Feb 17;25(1):104
BMC cardiovascular disorders 2025 Feb 17;25(1):104
Membrane-Associated RING-CH-Type Finger 6 Protects against Hypertension-Induced Cardiac Remodeling by Suppressing Cardiomyocyte Ferroptosis Through the Degradation of ACSL4.
Hao R, Wang X, Liu C, Xue J
Inflammation 2025 Dec;48(6):4475-4491
Inflammation 2025 Dec;48(6):4475-4491
USP36 suppresses breast cancer cell ferroptosis by regulating the ubiquitination and stability of KIF2C.
Chen Y, Hong S, Wu F, Xu S, Yang Y, Xu J
Biochemical pharmacology 2025 Dec;242(Pt 2):117196
Biochemical pharmacology 2025 Dec;242(Pt 2):117196
USP18 promotes ferroptosis in lipopolysaccharide-induced human kidney organoids by stabilizing STING1.
Yang H, Zhao L, Kong W, Liu S, Zhou Q, Lang X, Lan L, Wang Y
Cell biology and toxicology 2025 Aug 20;41(1):126
Cell biology and toxicology 2025 Aug 20;41(1):126
AMPK regulates ARF1 localization to membrane contact sites to facilitate fatty acid transfer between lipid droplets and mitochondria.
Chen L, Liu Y, Zhang J, Song T, Wu J, Ren Z
Cell death & disease 2025 Aug 18;16(1):623
Cell death & disease 2025 Aug 18;16(1):623
Nuclear accumulation of YTHDF1 regulates mRNA splicing in the DNA damage response.
Hou J, Gao Y, Han B, Yan S, Wei S, Gao X
Science advances 2025 Apr 18;11(16):eado7660
Science advances 2025 Apr 18;11(16):eado7660
PMEPA1 promotes gastric cancer cell proliferation by regulating the ubiquitin-mediated degradation of 14-3-3σ and promoting cell cycle progression.
Huang H, Sun R, Xu Y, Liu R, Chen Z
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 2024;57:e13985
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 2024;57:e13985
Identification of DNA methylation-regulated WEE1 with potential implications in prognosis and immunotherapy for low-grade glioma.
Zhong WJ, Zhang LZ, Yue F, Yuan L, Zhang Q, Li X, Lin L
Cancer biomarkers : section A of Disease markers 2024;40(3-4):297-317
Cancer biomarkers : section A of Disease markers 2024;40(3-4):297-317
METTL3 Inhibition Suppresses Cell Growth and Survival in Colorectal Cancer via ASNS Downregulation.
Yu Y, Hai Y, Zhou H, Bao W, Hu X, Gao Y, Wu J
Journal of Cancer 2024;15(15):4853-4865
Journal of Cancer 2024;15(15):4853-4865
IMPC-based screening revealed that ROBO1 can regulate osteoporosis by inhibiting osteogenic differentiation.
Zhang X, Wang Y, Zheng M, Wei Q, Zhang R, Zhu K, Zhai Q, Xu Y
Frontiers in cell and developmental biology 2024;12:1450215
Frontiers in cell and developmental biology 2024;12:1450215
Deubiquitinating Enzyme USP19 Regulates Ferroptosis and Mitochondrial Damage in SH-SY5Y Cells by Targeting the NOX4 Protein.
Yu W, Zhuang S, Zhan M, Chen Y, Zhang J, Chen L, Tu C, Zheng L, Chen S
Journal of Alzheimer's disease : JAD 2024;100(3):799-808
Journal of Alzheimer's disease : JAD 2024;100(3):799-808
The metabolic activation of and platelet response to vicagrel vary with P-glycoprotein deficiency, rather than P-glycoprotein inhibition, in mice.
Li XM, Li HD, Shao YY, Ji JZ, Tang K, Zheng ZD, Wu Y, Ding PJ, Wang J, Jiang LP, Tai T, Mi QY, Fu M, Xie HG
Xenobiotica; the fate of foreign compounds in biological systems 2024 Sep;54(9):759-769
Xenobiotica; the fate of foreign compounds in biological systems 2024 Sep;54(9):759-769
The FAcilitates Chromatin Transcription complex regulates the ratio of glycolysis to oxidative phosphorylation in neural stem cells.
Lou Y, Wu L, Cai W, Deng H, Sang R, Xie S, Xu X, Yuan X, Wu C, Xu M, Ge W, Xi Y, Yang X
Journal of molecular cell biology 2024 Sep 30;16(4)
Journal of molecular cell biology 2024 Sep 30;16(4)
FBXO2 promotes the progression of papillary thyroid carcinoma through the p53 pathway.
Guo W, Ren Y, Qiu X
Scientific reports 2024 Sep 29;14(1):22574
Scientific reports 2024 Sep 29;14(1):22574
Inflammatory Signaling via PEIZO1 Engages and Enhances the LPS-Mediated Apoptosis during Clinical Mastitis.
Wang J, Li M, Wu W, Zhang H, Yang Y, Usman M, Aernouts B, Loor JJ, Xu C
Journal of agricultural and food chemistry 2024 Sep 18;72(37):20321-20330
Journal of agricultural and food chemistry 2024 Sep 18;72(37):20321-20330
Strategic targeting of miR-183 and β-catenin to enhance BMSC stemness in age-related osteoporosis therapy.
Jiang N, Jiang J, Wang Q, Hao J, Yang R, Tian X, Wang H
Scientific reports 2024 Sep 14;14(1):21489
Scientific reports 2024 Sep 14;14(1):21489
Targeting PNPO to suppress tumor growth via inhibiting autophagic flux and to reverse paclitaxel resistance in ovarian cancer.
Li X, Guan W, Liu H, Yuan J, Wang F, Guan B, Chen J, Lu Q, Zhang L, Xu G
Apoptosis : an international journal on programmed cell death 2024 Oct;29(9-10):1546-1563
Apoptosis : an international journal on programmed cell death 2024 Oct;29(9-10):1546-1563
MicroRNA hsa-let-7e-5p in hUC-MSC-EVs alleviates oral mucositis by targeting TAB2.
Lin S, Lai D, Tian Y, Lai F, Long M, Ji C, Hao G
Scandinavian journal of immunology 2024 Oct;100(4):e13399
Scandinavian journal of immunology 2024 Oct;100(4):e13399
Tumor cell-intrinsic Piezo2 drives radioresistance by impairing CD8+ T cell stemness maintenance.
Miao N, Cao D, Jin J, Ma G, Yu H, Qu J, Li G, Gao C, Dong D, Xia F, Li W
The Journal of experimental medicine 2024 Oct 7;221(10)
The Journal of experimental medicine 2024 Oct 7;221(10)
Construction of an autophagy-related genes risk model as predicting prognosis: BAG1 suppresses growth of clear cell renal cell carcinoma.
Guo J, Chen Q, Han S, Wang T, Xia K, Yu B, Qiu T, Zhou J
International immunopharmacology 2024 Oct 25;140:112737
International immunopharmacology 2024 Oct 25;140:112737
eIF6 deficiency regulates gut microbiota, decreases systemic inflammation, and alleviates atherosclerosis.
Wang Z, Yang S, Tong L, Li X, Mao W, Yuan H, Chen Y, Zhang S, Zhang H, Chen R
mSystems 2024 Oct 22;9(10):e0059524
mSystems 2024 Oct 22;9(10):e0059524
Leukemia inhibitory factor protects against experimental periodontitis through immuno-modulations of both macrophages and periodontal ligament fibroblasts.
Ou Y, Fan L, Wang X, Xia H, Cheng M, Huang J, Liang Y, Wang Y, Zhou Y
Journal of periodontology 2024 Nov;95(11):1073-1085
Journal of periodontology 2024 Nov;95(11):1073-1085
HRD1 reduction promotes cholesterol-induced vascular smooth muscle cell phenotypic change via endoplasmic reticulum stress.
Wang L, Ren Z, Wu L, Zhang X, Wang M, Niu H, He X, Wang H, Chen Y, Shi G, Qian X
Molecular and cellular biochemistry 2024 Nov;479(11):3021-3036
Molecular and cellular biochemistry 2024 Nov;479(11):3021-3036
The PRMT6/STAT1/ACSL1 axis promotes ferroptosis in diabetic nephropathy.
Hong J, Li X, Hao Y, Xu H, Yu L, Meng Z, Zhang J, Zhu M
Cell death and differentiation 2024 Nov;31(11):1561-1575
Cell death and differentiation 2024 Nov;31(11):1561-1575
Luteolin protects against myocardial ischemia/reperfusion injury by reducing oxidative stress and apoptosis through the p53 pathway.
Zhai P, Ouyang XH, Yang ML, Lin L, Li JY, Li YM, Cheng X, Zhu R, Hu DS
Journal of integrative medicine 2024 Nov;22(6):652-664
Journal of integrative medicine 2024 Nov;22(6):652-664
CCDC50 mediates the clearance of protein aggregates to prevent cellular proteotoxicity.
Ye Y, Jia P, Miao J, Wang Y, Li Z, Lin Y, He M, Liu S, Zheng BR, Wu J, Pan J, Li CM, Hou P, Guo D
Autophagy 2024 Nov;20(11):2529-2539
Autophagy 2024 Nov;20(11):2529-2539
Angiotensin II depends on hippo/YAP signaling to reprogram angiogenesis and promote liver fibrosis.
Zhou Y, Liang P, Bi T, Tang B, Zhu X, Liu X, Wang H, Shen H, Sun Q, Yang S, Ren W
Cellular signalling 2024 Nov;123:111355
Cellular signalling 2024 Nov;123:111355
Comparative proteomic analysis between tumor tissues and intratumoral exosomes from lung adenocarcinoma patients identifies PAFAH1B3 as an exosomal protein key for initiating metastasis in lung adenocarcinoma.
Wang C, Xiao L, Gao L, Wu J, Wang S, Zheng MM, Qin CT, Huang XG, Zhou L, Xu WJ, Li HG, Chen WL, Zhu LH, Jin X
Heliyon 2024 Nov 15;10(21):e39859
Heliyon 2024 Nov 15;10(21):e39859
MDM4 inhibits ferroptosis in p53 mutant colon cancer via regulating TRIM21/GPX4 expression.
Liu J, Wei X, Xie Y, Yan Y, Xue S, Wang X, Chen H, Pan Q, Yan S, Zheng X, Huang Q
Cell death & disease 2024 Nov 14;15(11):825
Cell death & disease 2024 Nov 14;15(11):825
Hepatocyte growth factor promotes melanoma metastasis through ubiquitin-specific peptidase 22-mediated integrins upregulation.
Gao Q, Li N, Pan Y, Chu P, Zhou Y, Jia H, Cheng Y, Xue G, Song J, Zhang Y, Zhu H, Sun J, Zhang B, Sun Z, Fang D
Cancer letters 2024 Nov 1;604:217196
Cancer letters 2024 Nov 1;604:217196
Stevioside Ameliorates Palmitic Acid-Induced Abnormal Glucose Uptake via the PDK4/AMPK/TBC1D1 Pathway in C2C12 Myotubes.
Zhang C, Li S, Li L, Wang R, Luo S, Li G
Endocrinology, diabetes & metabolism 2024 May;7(3):e00482
Endocrinology, diabetes & metabolism 2024 May;7(3):e00482
Intravitreal Delivery of rAAV2-hSyn-hRS1 Results in Retinal Ganglion Cell-Specific Gene Expression and Retinal Improvement in the Rs1-KO Mouse.
Zheng Y, Xu X, Fan R, Jiang H, Guo Q, Han X, Liu Y, Luo G
Human gene therapy 2024 May;35(9-10):342-354
Human gene therapy 2024 May;35(9-10):342-354
The Jagged-1/Notch1 Signaling Pathway Promotes the Construction of Tissue-Engineered Heart Valves.
Liu K, Wei ZY, Zhong XH, Liu X, Chen H, Pan Y, Zeng W
Tissue engineering. Part A 2024 May;30(9-10):381-392
Tissue engineering. Part A 2024 May;30(9-10):381-392
Myricanol improves metabolic profiles in dexamethasone induced lipid and protein metabolism disorders in mice.
Li T, Hu X, Fan L, Yang Y, He K
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 May;174:116557
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 May;174:116557
QDPR deficiency drives immune suppression in pancreatic cancer.
Liu J, He X, Deng S, Zhao S, Zhang S, Chen Z, Xue C, Zeng L, Zhao H, Zhou Y, Bai R, Xu Z, Liu S, Zhou Q, Li M, Zhang J, Huang X, Chen R, Wang L, Lin D, Zheng J
Cell metabolism 2024 May 7;36(5):984-999.e8
Cell metabolism 2024 May 7;36(5):984-999.e8
Effects of Pemafibrate on Reducing Oxidative Stress and Augmenting Angiogenesis in Ischemic Limb Tissue.
Anegawa T, Sasaki KI, Ishizaki Y, Negoto S, Oryoji A, Nakamura E, Otsuka H, Hiromatsu S, Fukumoto Y, Tayama E
The Kurume medical journal 2024 May 14;69(3.4):167-174
The Kurume medical journal 2024 May 14;69(3.4):167-174
High fat diet ameliorates mitochondrial cardiomyopathy in CHCHD10 mutant mice.
Southwell N, Manzo O, Bacman S, Zhao D, Sayles NM, Dash J, Fujita K, D'Aurelio M, Di Lorenzo A, Manfredi G, Kawamata H
EMBO molecular medicine 2024 Jun;16(6):1352-1378
EMBO molecular medicine 2024 Jun;16(6):1352-1378
The regulation of MFG-E8 on the mitophagy in diabetic sarcopenia via the HSPA1L-Parkin pathway and the effect of D-pinitol.
Zhao W, Zhao B, Meng X, Li B, Wang Y, Yu F, Fu C, Yu X, Li X, Dai C, Wang J, Gao H, Cheng M
Journal of cachexia, sarcopenia and muscle 2024 Jun;15(3):934-948
Journal of cachexia, sarcopenia and muscle 2024 Jun;15(3):934-948
ARID1A loss promotes RNA editing of CDK13 in an ADAR1-dependent manner.
Zhu T, Li Q, Zhang Z, Shi J, Li Y, Zhang F, Li L, Song X, Shen J, Jia R
BMC biology 2024 Jun 5;22(1):132
BMC biology 2024 Jun 5;22(1):132
Lumbrokinase Extracted from Earthworms Synergizes with Bevacizumab and Chemotherapeutics in Treating Non-Small Cell Lung Cancer by Targeted Inactivation of BPTF/VEGF and NF-κB/COX-2 Signaling.
Hua C, Guo Z, Dai M, Zhou J, Ge H, Xue G, Xu F, Ru L, Lv K, Zhang G, Zheng L, Wang M, Teng Y, Yu W, Guo W
Biomolecules 2024 Jun 23;14(7)
Biomolecules 2024 Jun 23;14(7)
d-mannose targets PD-1 to lysosomal degradation and enhances T cell-mediated anti-tumor immunity.
Dong W, Lin M, Zhang R, Sun X, Li H, Liu T, Xu Y, Lv L
Cancer letters 2024 Jun 1;591:216883
Cancer letters 2024 Jun 1;591:216883
Accumulation of γδT cells in the decidua is promoted by RANKL which upregulates ICAM-1 via NF-κB.
Chang RQ, Dai JC, Qiu YH, Liang Y, Hu XY, Li MQ, He F
Reproduction (Cambridge, England) 2024 Jun 1;167(6)
Reproduction (Cambridge, England) 2024 Jun 1;167(6)
AN698/40746067 suppresses bone marrow adiposity to ameliorate hyperlipidemia-induced osteoporosis through targeted inhibition of ENTR1.
Ren H, Mao K, Yuan X, Mu Y, Zhao S, Fan X, Zhu L, Ye Z, Lan J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jul;176:116843
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jul;176:116843
H3K27ac acts as a molecular switch for doxorubicin-induced activation of cardiotoxic genes.
Hong Y, Li X, Li J, He Q, Huang M, Tang Y, Chen X, Chen J, Tang KJ, Wei C
Clinical epigenetics 2024 Jul 16;16(1):91
Clinical epigenetics 2024 Jul 16;16(1):91
Shenqu xiaoshi oral solution enhances digestive function and stabilizes the gastrointestinal microbiota of juvenile rats with infantile anorexia.
Zhao M, Xiang T, Dong Z, Liu G, Wang P, Qi X, Hao Q, Han N, Liu Z, Li S, Yin J, Zhai J
Journal of ethnopharmacology 2024 Jan 30;319(Pt 1):117112
Journal of ethnopharmacology 2024 Jan 30;319(Pt 1):117112
MDM4 was associated with poor prognosis and tumor-immune infiltration of cancers.
Liu J, Yang J, Pan Q, Wang X, Wang X, Chen H, Zheng X, Huang Q
European journal of medical research 2024 Jan 27;29(1):79
European journal of medical research 2024 Jan 27;29(1):79
Overcoming therapeutic resistance in oncolytic herpes virotherapy by targeting IGF2BP3-induced NETosis in malignant glioma.
Dai W, Tian R, Yu L, Bian S, Chen Y, Yin B, Luan Y, Chen S, Fan Z, Yan R, Pan X, Hou Y, Li R, Chen J, Shu M
Nature communications 2024 Jan 2;15(1):131
Nature communications 2024 Jan 2;15(1):131
Identification and experimental validation of Stearoyl-CoA desaturase is a new drug therapeutic target for osteosarcoma.
Nie J, He C, Shu Z, Liu N, Zhong Y, Long X, Liu J, Yang F, Liu Z, Huang P
European journal of pharmacology 2024 Jan 15;963:176249
European journal of pharmacology 2024 Jan 15;963:176249
TRIM56 protects against nonalcoholic fatty liver disease by promoting the degradation of fatty acid synthase.
Xu S, Wu X, Wang S, Xu M, Fang T, Ma X, Chen M, Fu J, Guo J, Tian S, Tian T, Cheng X, Yang H, Zhou J, Wang Z, Yin Y, Xu W, Xu F, Yan J, Wang Z, Luo S, Zhang XJ, Ji YX, Weng J
The Journal of clinical investigation 2024 Jan 11;134(5)
The Journal of clinical investigation 2024 Jan 11;134(5)
Hesperetin promotes bladder cancer cells death via the PI3K/AKT pathway by network pharmacology and molecular docking.
Lv Y, Liu Z, Deng L, Xia S, Mu Q, Xiao B, Xiu Y, Liu Z
Scientific reports 2024 Jan 10;14(1):1009
Scientific reports 2024 Jan 10;14(1):1009
AZD7762 induces CRBN dependent BAG3 degradation through ubiquitin-proteasome pathway.
Liao Y, Yuan C, Huang M, Si W, Li D, Wu W, Zhang S, Wu R, Quan Y, Yu X, Liao S
Anti-cancer drugs 2024 Jan 1;35(1):46-54
Anti-cancer drugs 2024 Jan 1;35(1):46-54
AMPK/PGC-1α and p53 modulate VDAC1 expression mediated by reduced ATP level and metabolic oxidative stress in neuronal cells.
Wang Z, Xu T, Sun Y, Zhang X, Wang X
Acta biochimica et biophysica Sinica 2024 Feb 25;56(2):162-173
Acta biochimica et biophysica Sinica 2024 Feb 25;56(2):162-173
Endothelium-specific deletion of p62 causes organ fibrosis and cardiac dysfunction.
Feng J, Li Y, Zhang Y, Sun S, Sun J, Xu Q, Ji X, Liu Y, Wan Q
Journal of translational medicine 2024 Feb 16;22(1):161
Journal of translational medicine 2024 Feb 16;22(1):161
ADAR1 Promotes Invasion and Migration and Inhibits Ferroptosis via the FAK/AKT Pathway in Colorectal Cancer.
He D, Niu C, Bai R, Chen N, Cui J
Molecular carcinogenesis 2024 Dec;63(12):2401-2413
Molecular carcinogenesis 2024 Dec;63(12):2401-2413
TRPM2 knockdown attenuates myocardial apoptosis and promotes autophagy in HFD/STZ-induced diabetic mice via regulating the MEK/ERK and mTORC1 signaling pathway.
Hu F, Lin C
Molecular and cellular biochemistry 2024 Dec;479(12):3307-3328
Molecular and cellular biochemistry 2024 Dec;479(12):3307-3328
Mesenchymal stem cells may alleviate angiotensin II-induced myocardial fibrosis and hypertrophy by upregulating SFRS3 expression.
Gu L, Wan X, Liu Y, Gong Z, Huang R, Shi Y, Liu H
Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology 2024 Dec;43(12):645-656
Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology 2024 Dec;43(12):645-656
Fibroblast growth factor 2 enhances BMSC stemness through ITGA2-dependent PI3K/AKT pathway activation.
Jiang N, Hu Z, Wang Q, Hao J, Yang R, Jiang J, Wang H
Journal of cellular physiology 2024 Dec;239(12):e31423
Journal of cellular physiology 2024 Dec;239(12):e31423
Neuroinvasive virus utilizes a lipid droplet surface protein, perilipin2, to restrict apoptosis by decreasing Bcl-2 ubiquitination.
Wang Q, Zhao J, Zhang M, Sun M, Fu ZF, Zhao L, Zhou M
Journal of virology 2024 Dec 17;98(12):e0160724
Journal of virology 2024 Dec 17;98(12):e0160724
Zishen Qingre Lishi Huayu Recipe May Ameliorate the Symptoms of PCOS Model Rats via Alleviating Systemic and Ovarian Inflammation.
Li X, Yi Y, Ren Y, Zhang Y, Wang CC, Liu C, Liu S, Zhan X, Yu X, Liang R
American journal of reproductive immunology (New York, N.Y. : 1989) 2024 Aug;92(2):e13918
American journal of reproductive immunology (New York, N.Y. : 1989) 2024 Aug;92(2):e13918
Nicotinamide protects against diabetic kidney disease through regulation of Sirt1.
Yang Y, Huang J, Xie L, Wang Y, Guo S, Wang M, Shao X, Liu W, Wang Y, Li Q, Wu X, Zhang Z, Zeng F, Gong W
Endocrine 2024 Aug;85(2):638-648
Endocrine 2024 Aug;85(2):638-648
Dietary sodium sulphate supplementation during mid-to-late gestation improves placental angiogenesis, bile acid metabolism, and serum amino acid concentrations of sows.
Zhou R, Zhe L, Lai SS, Wen HM, Hu L, Zhang XL, Zhuo Y, Xu SY, Lin Y, Feng B, Che LQ, Wu D, Fang ZF
Animal : an international journal of animal bioscience 2024 Aug;18(8):101237
Animal : an international journal of animal bioscience 2024 Aug;18(8):101237
Accumulated β-catenin is associated with human atrial fibrosis and atrial fibrillation.
Bai Y, Li R, Hao JF, Chen LW, Liu ST, Zhang XL, Lip GYH, Yang JK, Zou YX, Wang H
Journal of translational medicine 2024 Aug 5;22(1):734
Journal of translational medicine 2024 Aug 5;22(1):734
Antitumor effects of a Sb-rich polyoxometalate on non-small-cell lung cancer by inducing ferroptosis and apoptosis.
Lin JW, Zhou Y, Xiao HP, Wu LL, Li PC, Huang MD, Xie D, Xu P, Li XX, Li ZX
Chemical science 2024 Aug 27;15(37):15367-76
Chemical science 2024 Aug 27;15(37):15367-76
SGK3 deficiency in macrophages suppresses angiotensin II-induced cardiac remodeling via regulating Ndufa13-mediated mitochondrial oxidative stress.
Ren J, Che Y, Li H, Gao H, Wang Y, Wang Y, Su H, Li Z, Li J, Qu P
Cellular and molecular life sciences : CMLS 2024 Aug 19;81(1):359
Cellular and molecular life sciences : CMLS 2024 Aug 19;81(1):359
USP36 regulates the proliferation, survival, and differentiation of hFOB1.19 osteoblast.
Yan J, Gu X, Gao X, Shao Y, Ji M
Journal of orthopaedic surgery and research 2024 Aug 17;19(1):483
Journal of orthopaedic surgery and research 2024 Aug 17;19(1):483
Heterozygous Gnaq deficiency enhances Ifi202b/IFI16 and NF-κB activation in endothelial cells and exacerbates lupus nephritis pathology.
Zhang L, He Y, Zhang M, Zhang J, Zhuang W, Sun Y, Chen X, Fu H, Tang X, Shi G
iScience 2024 Aug 16;27(8):110350
iScience 2024 Aug 16;27(8):110350
Endothelial H(2)S-AMPK dysfunction upregulates the angiocrine factor PAI-1 and contributes to lung fibrosis.
Chen X, Wang H, Wu C, Li X, Huang X, Ren Y, Pu Q, Cao Z, Tang X, Ding BS
Redox biology 2024 Apr;70:103038
Redox biology 2024 Apr;70:103038
Rapamycin protects Sertoli cells against BPA-induced autophagy disorders.
Nie J, Mao Z, Zeng X, Zhao X
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Apr;186:114510
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Apr;186:114510
H(2)S-Releasing Versatile Montmorillonite Nanoformulation Trilogically Renovates the Gut Microenvironment for Inflammatory Bowel Disease Modulation.
Jin T, Lu H, Zhou Q, Chen D, Zeng Y, Shi J, Zhang Y, Wang X, Shen X, Cai X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Apr;11(14):e2308092
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Apr;11(14):e2308092
Exercise training affects calcium ion transport by downregulating the CACNA2D1 protein to reduce hypertension-induced myocardial injury in mice.
Gao S, Yao W, Zhou R, Pei Z
iScience 2024 Apr 19;27(4):109351
iScience 2024 Apr 19;27(4):109351
Pharmacological Activation of Rev-erbα Attenuates Doxorubicin-Induced Cardiotoxicity by PGC-1α Signaling Pathway.
Zou R, Wang S, Cai H, Wang Y, Wang C
Cardiovascular therapeutics 2023;2023:2108584
Cardiovascular therapeutics 2023;2023:2108584
Sema3A Modified PDLSCs Exhibited Enhanced Osteogenic Capabilities and Stimulated Differentiation of Pre-Osteoblasts.
Wang W, Chen B, Yang J, Li Y, Ding H, Liu H, Yuan C
Cell biochemistry and biophysics 2023 Sep;81(3):543-552
Cell biochemistry and biophysics 2023 Sep;81(3):543-552
Effect of Tamoxifen on Proteome Expression during In Vitro Myogenesis in Murine Skeletal Muscle C(2)C(12) Cells.
Morris EA, Abreu A, Scordilis SP
Journal of proteome research 2023 Sep 1;22(9):3040-3053
Journal of proteome research 2023 Sep 1;22(9):3040-3053
Atorvastatin rescues vascular endothelial injury in hypertension by WWP2-mediated ubiquitination and degradation of ATP5A.
Yin Z, You S, Zhang S, Zhang L, Wu B, Huang X, Lu S, Cao L, Zhang Y, Li D, Zhang X, Liu J, Sun Y, Zhang N
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Oct;166:115228
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Oct;166:115228
Melatonin alleviates depression-like behaviors and cognitive dysfunction in mice by regulating the circadian rhythm of AQP4 polarization.
Yao D, Li R, Hao J, Huang H, Wang X, Ran L, Fang Y, He Y, Wang W, Liu X, Wang M
Translational psychiatry 2023 Oct 6;13(1):310
Translational psychiatry 2023 Oct 6;13(1):310
Inhibition of Sirt2 Decreases ApoE Secretion in Astrocytes and Microglial Cells.
Chen Y, Zhou C, Abdelhamid M, Jung CG, Michikawa M
Journal of biochemistry 2023 Oct 31;174(5):409-420
Journal of biochemistry 2023 Oct 31;174(5):409-420
Depletion of PIEZO1 expression is accompanied by upregulating p53 signaling in mice with perioperative neurocognitive disorder.
Bai F, Huang L, Long Z, Zhang M, Deng Q, Huang J, Bao X, Hao X, Li H
Functional & integrative genomics 2023 Oct 27;23(4):327
Functional & integrative genomics 2023 Oct 27;23(4):327
ZSCAN4 interacts with PARP1 to promote DNA repair in mouse embryonic stem cells.
Tsai LK, Peng M, Chang CC, Wen L, Liu L, Liang X, Chen YE, Xu J, Sung LY
Cell & bioscience 2023 Oct 24;13(1):193
Cell & bioscience 2023 Oct 24;13(1):193
Human amnion-derived mesenchymal stem cells improve subclinical hypothyroidism by immunocompetence mediating apoptosis inhibition on thyroid cells in aged mice.
Li C, Rui Q, Dong X, Ning S, Zhou J, Wu H, Jiang C, Cui Y, Liu J, Jiang J, Qin L
Cell and tissue research 2023 Nov;394(2):309-323
Cell and tissue research 2023 Nov;394(2):309-323
Integrated network pharmacology to investigate the mechanism of Salvia miltiorrhiza Bunge in the treatment of myocardial infarction.
Huang X, Zhang M, Song Y, Sun B, Lin L, Song X, Li C
Journal of cellular and molecular medicine 2023 Nov;27(22):3514-3525
Journal of cellular and molecular medicine 2023 Nov;27(22):3514-3525
CCDC127 regulates lipid droplet homeostasis by enhancing mitochondria-ER contacts.
Xia Y, Zhang Y, Sun Y, He L
Biochemical and biophysical research communications 2023 Nov 26;683:149116
Biochemical and biophysical research communications 2023 Nov 26;683:149116
NUAK1 promotes tumor metastasis through upregulating slug transcription in esophageal squamous cell carcinoma.
Yang H, Wei Z, Song Y, Du K, Yin N, Lu H, Li B, Hou L, Xing P, Chen L, Wang C, Xie S
Cancer cell international 2023 Nov 2;23(1):258
Cancer cell international 2023 Nov 2;23(1):258
Crucial role of hsa-mir-503, hsa-mir-1247, and their validation in prostate cancer.
Hu P, Wang T, Yan H, Huang Y, Zhao Y, Gao Y
Aging 2023 Nov 16;15(22):12966-12981
Aging 2023 Nov 16;15(22):12966-12981
Active post-transcriptional regulation and ACLY-mediated acetyl-CoA synthesis as a pivotal target of Shuang-Huang-Sheng-Bai formula for lung adenocarcinoma treatment.
Liu D, Dong C, Wang F, Liu W, Jin X, Qi SL, Liu L, Jin Q, Wang S, Wu J, Wang C, Yang J, Deng H, Cai Y, Yang L, Qin J, Zhang C, Yang X, Wang MS, Yu G, Xue YW, Wang Z, Ge GB, Xu Z, Chen WL
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 May;113:154732
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 May;113:154732
Down-regulation of WWP2 aggravates Type 2 diabetes mellitus-induced vascular endothelial injury through modulating ubiquitination and degradation of DDX3X.
You S, Xu J, Yin Z, Wu B, Wang P, Hao M, Cheng C, Liu M, Zhao Y, Jia P, Jiang H, Li D, Cao L, Zhang X, Zhang Y, Sun Y, Zhang N
Cardiovascular diabetology 2023 May 6;22(1):107
Cardiovascular diabetology 2023 May 6;22(1):107
SIRT2 Deficiency Aggravates Diet-Induced Nonalcoholic Fatty Liver Disease through Modulating Gut Microbiota and Metabolites.
Li X, Du Y, Xue C, Kang X, Sun C, Peng H, Fang L, Han Y, Xu X, Zhao C
International journal of molecular sciences 2023 May 18;24(10)
International journal of molecular sciences 2023 May 18;24(10)
ACTA1 H40Y mutant iPSC-derived skeletal myocytes display mitochondrial defects in an in vitro model of nemaline myopathy.
Gartz M, Haberman M, Sutton J, Slick RA, Luttrell SM, Mack DL, Lawlor MW
Experimental cell research 2023 Mar 15;424(2):113507
Experimental cell research 2023 Mar 15;424(2):113507
Rare sugar L-sorbose exerts antitumor activity by impairing glucose metabolism.
Xu HL, Zhou X, Chen S, Xu S, Li Z, Nakanishi H, Gao XD
Communications biology 2023 Mar 11;6(1):259
Communications biology 2023 Mar 11;6(1):259
Inhibition of TLR4 Alleviates Heat Stroke-Induced Cardiomyocyte Injury by Down-Regulating Inflammation and Ferroptosis.
Chen D, Geng Y, Deng Z, Li P, Xue S, Xu T, Li G
Molecules (Basel, Switzerland) 2023 Mar 1;28(5)
Molecules (Basel, Switzerland) 2023 Mar 1;28(5)
Gallocatechin Gallate Inhibits the Replication of Pseudorabies Virus via Suppressing the Entry and Release Stages in Its Replication Cycle.
Bo Z, Zhu J, Guo M, Zhang C, Cao Y, Zhang X, Wu Y
Veterinary sciences 2023 Mar 1;10(3)
Veterinary sciences 2023 Mar 1;10(3)
Sleep Deprivation Promotes Endothelial Inflammation and Atherogenesis by Reducing Exosomal miR-182-5p.
Li X, Cao Y, Xu X, Wang C, Ni Q, Lv X, Yang C, Zhang Z, Qi X, Song G
Arteriosclerosis, thrombosis, and vascular biology 2023 Jun;43(6):995-1014
Arteriosclerosis, thrombosis, and vascular biology 2023 Jun;43(6):995-1014
The Valsa Mali effector Vm1G-1794 protects the aggregated MdEF-Tu from autophagic degradation to promote infection in apple.
Che R, Liu C, Wang Q, Tu W, Wang P, Li C, Gong X, Mao K, Feng H, Huang L, Li P, Ma F
Autophagy 2023 Jun;19(6):1745-1763
Autophagy 2023 Jun;19(6):1745-1763
5'-tiRNA-Gln inhibits hepatocellular carcinoma progression by repressing translation through the interaction with eukaryotic initiation factor 4A-I.
Wu C, Liu D, Zhang L, Wang J, Ding Y, Sun Z, Wang W
Frontiers of medicine 2023 Jun;17(3):476-492
Frontiers of medicine 2023 Jun;17(3):476-492
MFN2 deficiency affects calcium homeostasis in lung adenocarcinoma cells via downregulation of UCP4.
Zhang J, Pan L, Zhang Q, Zhao Y, Wang W, Lin N, Zhang S, Wu Q
FEBS open bio 2023 Jun;13(6):1107-1124
FEBS open bio 2023 Jun;13(6):1107-1124
Aloe-emodin ameliorated MI-induced cardiac remodeling in mice via inhibiting TGF-β/SMAD signaling via up-regulating SMAD7.
Yu J, Zhao X, Yan X, Li W, Liu Y, Wang J, Wang J, Yang Y, Hao Y, Liang Z, Tao Y, Yuan Y, Du Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jun;114:154793
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jun;114:154793
Curcumol, a major terpenoid from Curcumae Rhizoma, attenuates human uterine leiomyoma cell development via the p38MAPK/NF-κB pathway.
Yu YH, Zhang HJ, Yang F, Xu L, Liu H
Journal of ethnopharmacology 2023 Jun 28;310:116311
Journal of ethnopharmacology 2023 Jun 28;310:116311
CaMKK2 alleviates myocardial ischemia/reperfusion injury by inhibiting oxidative stress and inflammation via the action on the AMPK-AKT-GSK-3β/Nrf2 signaling cascade.
Li C, Hao J, Qiu H, Xin H
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2023 Jul;72(7):1409-1425
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2023 Jul;72(7):1409-1425
Nucleolus assembly impairment leads to two-cell transcriptional repression via NPM1-mediated PRC2 recruitment.
Li D, Cao R, Li Q, Yang Y, Tang A, Zhang J, Liu Q
Nature structural & molecular biology 2023 Jul;30(7):914-925
Nature structural & molecular biology 2023 Jul;30(7):914-925
NCOA7 Regulates Growth and Metastasis of Clear Cell Renal Cell Carcinoma via MAPK/ERK Signaling Pathway.
Guo J, Ke S, Chen Q, Zhou J, Guo J, Qiu T
International journal of molecular sciences 2023 Jul 18;24(14)
International journal of molecular sciences 2023 Jul 18;24(14)
HMOX1 Promotes Ferroptosis Induced by Erastin in Lens Epithelial Cell through Modulates Fe(2+) Production.
Liao S, Huang M, Liao Y, Yuan C
Current eye research 2023 Jan;48(1):25-33
Current eye research 2023 Jan;48(1):25-33
Metabolomic and transcriptomic studies of improvements in myocardial infarction due to Pycr1 deletion.
Xue Z, Pan Y, Kong X, Zhang J, Wu D, Zhou B
Journal of cellular and molecular medicine 2023 Jan;27(1):89-100
Journal of cellular and molecular medicine 2023 Jan;27(1):89-100
CMTM6 overexpression confers trastuzumab resistance in HER2-positive breast cancer.
Xing F, Gao H, Chen G, Sun L, Sun J, Qiao X, Xue J, Liu C
Molecular cancer 2023 Jan 10;22(1):6
Molecular cancer 2023 Jan 10;22(1):6
The protective effect of inhibiting mitochondrial fission on the juvenile rat brain following PTZ kindling through inhibiting the BCL2L13/LC3 mitophagy pathway.
Fang Q, Zheng S, Chen Q, Chen L, Yang Y, Wang Y, Zhang H, Chen J
Metabolic brain disease 2023 Feb;38(2):453-466
Metabolic brain disease 2023 Feb;38(2):453-466
G9a inhibition promotes the formation of pacemaker-like cells by reducing the enrichment of H3K9me2 in the HCN4 promoter region.
Xu P, Jin K, Zhou J, Gu J, Gu X, Dong L, Sun X
Molecular medicine reports 2023 Feb;27(2)
Molecular medicine reports 2023 Feb;27(2)
Lenvatinib inhibits intrahepatic cholangiocarcinoma via Gadd45a-mediated cell cycle arrest.
Yan X, Wang D, Ning Z, Meng ZQ
Discover oncology 2023 Feb 23;14(1):26
Discover oncology 2023 Feb 23;14(1):26
SIRT3 promotes metabolic maturation of human iPSC-derived cardiomyocytes via OPA1-controlled mitochondrial dynamics.
Wang R, Xu H, Tan B, Yi Q, Sun Y, Xiang H, Chen T, Liu H, Xie Q, Wang L, Tian J, Zhu J
Free radical biology & medicine 2023 Feb 1;195:270-282
Free radical biology & medicine 2023 Feb 1;195:270-282
LOC102549726/miR-760-3p network is involved in the progression of ISO-induced pathological cardiomyocyte hypertrophy via endoplasmic reticulum stress.
Chen B, Tan L, Wang Y, Yang L, Liu J, Chen D, Huang S, Mao F, Lian J
Journal of molecular histology 2023 Dec;54(6):675-687
Journal of molecular histology 2023 Dec;54(6):675-687
The effect of cold exposure on the levels of glucocorticoids, 11-hydroxysteroid dehydrogenase 2, and placental vascularization in a rat model.
Zhang QJ, Chen SW, Xu X, Zhang HL, Yan JY
European review for medical and pharmacological sciences 2023 Dec;27(24):11961-11974
European review for medical and pharmacological sciences 2023 Dec;27(24):11961-11974
miR-146a-5p Modulates Adult Hippocampal Neurogenesis Deficits Through Klf4/p-Stat3 Signaling in APP/PS1 Mice.
Deng LJ, Wu D, Yang XF, Li T
Neuroscience 2023 Aug 21;526:314-325
Neuroscience 2023 Aug 21;526:314-325
Orexin-A Reverse Bone Mass Loss Induced by Chronic Intermittent Hypoxia Through OX1R-Nrf2/HIF-1α Pathway.
Gu H, Ru Y, Wang W, Cai G, Gu L, Ye J, Zhang WB, Wang L
Drug design, development and therapy 2022;16:2145-2160
Drug design, development and therapy 2022;16:2145-2160
Matrine, a potential c-Myc inhibitor, suppresses ribosome biogenesis and nucleotide metabolism in myeloid leukemia.
Zhong WJ, Ma L, Yang F, Cao J, Tan J, Li B
Frontiers in pharmacology 2022;13:1027441
Frontiers in pharmacology 2022;13:1027441
ITGB5 promotes innate radiation resistance in pancreatic adenocarcinoma by promoting DNA damage repair and the MEK/ERK signaling pathway.
Wen X, Chen S, Chen X, Qiu H, Wang W, Zhang N, Liu W, Wang T, Ding X, Zhang L
Frontiers in oncology 2022;12:887068
Frontiers in oncology 2022;12:887068
DJ-1 promotes osteosarcoma progression through activating CDK4/RB/E2F1 signaling pathway.
Han Z, Wang L, Wang D, Zhang L, Bi Y, Zheng X, Liu W, Bai G, Wang Z, Wan W, Ma Y, Cai X, Liu T, Jia Q
Frontiers in oncology 2022;12:1036401
Frontiers in oncology 2022;12:1036401
Multi-Omics Analysis of MCM2 as a Promising Biomarker in Pan-Cancer.
Yuan J, Lan H, Huang D, Guo X, Liu C, Liu S, Zhang P, Cheng Y, Xiao S
Frontiers in cell and developmental biology 2022;10:852135
Frontiers in cell and developmental biology 2022;10:852135
Targeting p65 to inhibit Cas3 transcription by Onjisaponin B for radiation damage therapy in p65+/- mice.
Wang TY, Hu YJ, Wang X, Li YF, Zhang F, Yan YD, Dou WT, Cheng CY, Xu P
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Sep;104:154317
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Sep;104:154317
Hace1 overexpression mitigates myocardial hypoxia/reoxygenation injury via the effects on Keap1/Nrf2 pathway.
Chen TY, Zheng SK
In vitro cellular & developmental biology. Animal 2022 Oct;58(9):830-839
In vitro cellular & developmental biology. Animal 2022 Oct;58(9):830-839
CAMSAP2 promotes colorectal cancer cell migration and invasion through activation of JNK/c-Jun/MMP-1 signaling pathway.
Wang X, Liu Y, Ding Y, Feng G
Scientific reports 2022 Oct 7;12(1):16899
Scientific reports 2022 Oct 7;12(1):16899
LINC00514 facilitates cell proliferation, migration, invasion, and epithelial-mesenchymal transition in non-small cell lung cancer by acting on the Wnt/β-catenin signaling pathway.
Zhu Y, Wu H, Yang X, Xiong Z, Zhao T, Gan X
Bioengineered 2022 May;13(5):13654-13666
Bioengineered 2022 May;13(5):13654-13666
Scutellarein protects against cardiac hypertrophy via suppressing TRAF2/NF-κB signaling pathway.
Shi X, Hu Y, Jiang Y, Wu J, Zhang C, Zhang J, Wu S, Wu Y, Dong W, Li J
Molecular biology reports 2022 Mar;49(3):2085-2095
Molecular biology reports 2022 Mar;49(3):2085-2095
Chlorine disinfection elevates the toxicity of polystyrene microplastics to human cells by inducing mitochondria-dependent apoptosis.
Qin J, Xia PF, Yuan XZ, Wang SG
Journal of hazardous materials 2022 Mar 5;425:127842
Journal of hazardous materials 2022 Mar 5;425:127842
TXNIP knockout improves cardiac function after myocardial infarction by promoting angiogenesis and reducing cardiomyocyte apoptosis.
Wang J, Wang XJ, Zhang Y, Shi WJ, Lei ZD, Jiao XY
Cardiovascular diagnosis and therapy 2022 Jun;12(3):289-304
Cardiovascular diagnosis and therapy 2022 Jun;12(3):289-304
Erectile dysfunction in hypospadiac male adult rats induced by maternal exposure to di-n-butyl phthalate.
Zhou X, Wang S, Zhou R, Zhang T, Wang Y, Zhang Q, Cong R, Ji C, Luan J, Yao L, Zhou X, Song N
Toxicology 2022 Jun 15;475:153227
Toxicology 2022 Jun 15;475:153227
LncRNA BACE1-AS promotes the progression of osteosarcoma through miR-762/SOX7 axis.
Wang C, Zhang T, Yang L, Na X, Qu Y
Molecular biology reports 2022 Jul;49(7):5853-5862
Molecular biology reports 2022 Jul;49(7):5853-5862
ZC3H4 promotes pulmonary fibrosis via an ER stress-related positive feedback loop.
Ghafoor H, Chu H, Huang J, Chen M, Wang S, Wang J, Chao J
Toxicology and applied pharmacology 2022 Jan 15;435:115856
Toxicology and applied pharmacology 2022 Jan 15;435:115856
BUB1B (BUB1 Mitotic Checkpoint Serine/Threonine Kinase B) promotes lung adenocarcinoma by interacting with Zinc Finger Protein ZNF143 and regulating glycolysis.
Zhou X, Yuan Y, Kuang H, Tang B, Zhang H, Zhang M
Bioengineered 2022 Feb;13(2):2471-2485
Bioengineered 2022 Feb;13(2):2471-2485
Design, synthesis and biological evaluation of novel 1,3,4,9-tetrahydropyrano[3,4-b]indoles as potential treatment of triple negative breast cancer by suppressing PI3K/AKT/mTOR pathway.
Qin J, Sun X, Ma Y, Cheng Y, Ma Q, Jing W, Qu S, Liu L
Bioorganic & medicinal chemistry 2022 Feb 1;55:116594
Bioorganic & medicinal chemistry 2022 Feb 1;55:116594
The RNA polymerase of cytoplasmically replicating Zika virus binds with chromatin DNA in nuclei and regulates host gene transcription.
Li P, Wu J, Liu S, Lu R, Jiang H, Wang N, Luo M, Guo L, Xiao J, Bu L, Liu L, Xing F, Peng H, Li C, Ma L, Zhao B, Zhou Z, Guo D
Proceedings of the National Academy of Sciences of the United States of America 2022 Dec 6;119(49):e2205013119
Proceedings of the National Academy of Sciences of the United States of America 2022 Dec 6;119(49):e2205013119
Functional investigation of SLC1A2 variants associated with epilepsy.
Qu Q, Zhang W, Wang J, Mai D, Ren S, Qu S, Zhang Y
Cell death & disease 2022 Dec 21;13(12):1063
Cell death & disease 2022 Dec 21;13(12):1063
RSL3 triggers glioma stem cell differentiation via the Tgm2/AKT/ID1 signaling axis.
Li M, Song D, Chen X, Wang X, Xu L, Yang M, Yang J, Kalvakolanu DV, Wei X, Liu X, Li Y, Guo B, Zhang L
Biochimica et biophysica acta. Molecular basis of disease 2022 Dec 1;1868(12):166529
Biochimica et biophysica acta. Molecular basis of disease 2022 Dec 1;1868(12):166529
Mitochondrial dysfunction by TFAM depletion disrupts self-renewal and lineage differentiation of human PSCs by affecting cell proliferation and YAP response.
Qi Y, Ye Y, Wang R, Yu S, Zhang Y, Lv J, Jin W, Xia S, Jiang W, Li Y, Zhang D
Redox biology 2022 Apr;50:102248
Redox biology 2022 Apr;50:102248
Luteolin alleviates cognitive impairment in Alzheimer's disease mouse model via inhibiting endoplasmic reticulum stress-dependent neuroinflammation.
Kou JJ, Shi JZ, He YY, Hao JJ, Zhang HY, Luo DM, Song JK, Yan Y, Xie XM, Du GH, Pang XB
Acta pharmacologica Sinica 2022 Apr;43(4):840-849
Acta pharmacologica Sinica 2022 Apr;43(4):840-849
NAP1L5 Promotes Nucleolar Hypertrophy and Is Required for Translation Activation During Cardiomyocyte Hypertrophy.
Guo N, Zheng D, Sun J, Lv J, Wang S, Fang Y, Zhao Z, Zeng S, Guo Q, Tong J, Wang Z
Frontiers in cardiovascular medicine 2021;8:791501
Frontiers in cardiovascular medicine 2021;8:791501
JNK signaling-dependent regulation of histone acetylation are involved in anacardic acid alleviates cardiomyocyte hypertrophy induced by phenylephrine.
Peng B, Peng C, Luo X, Wu S, Mao Q, Zhang H, Han X
PloS one 2021;16(12):e0261388
PloS one 2021;16(12):e0261388
Interactions between the ERK1/2 signaling pathway and PCAF play a key role in PE‑induced cardiomyocyte hypertrophy.
Mao Q, Wu S, Peng C, Peng B, Luo X, Huang L, Zhang H
Molecular medicine reports 2021 Sep;24(3)
Molecular medicine reports 2021 Sep;24(3)
Diosgenin exerts anti-tumor effects through inactivation of cAMP/PKA/CREB signaling pathway in colorectal cancer.
Li SY, Shang J, Mao XM, Fan R, Li HQ, Li RH, Shen DY
European journal of pharmacology 2021 Oct 5;908:174370
European journal of pharmacology 2021 Oct 5;908:174370
A novel SIRT6 activator ameliorates neuroinflammation and ischemic brain injury via EZH2/FOXC1 axis.
He T, Shang J, Gao C, Guan X, Chen Y, Zhu L, Zhang L, Zhang C, Zhang J, Pang T
Acta pharmaceutica Sinica. B 2021 Mar;11(3):708-726
Acta pharmaceutica Sinica. B 2021 Mar;11(3):708-726
PGC1α Promotes Cisplatin Resistance in Ovarian Cancer by Regulating the HSP70/HK2/VDAC1 Signaling Pathway.
Li Y, Kang J, Fu J, Luo H, Liu Y, Li Y, Sun L
International journal of molecular sciences 2021 Mar 3;22(5)
International journal of molecular sciences 2021 Mar 3;22(5)
Overexpression of retinoid X receptor beta provides protection against oxidized low-density lipoprotein-induced inflammation via regulating PGC1α-dependent mitochondrial homeostasis in endothelial cells.
Zeng Y, Yan Wang C, Xu J, Le Xu X
Biochemical pharmacology 2021 Jun;188:114559
Biochemical pharmacology 2021 Jun;188:114559
Different roles of BAG3 in cardiac physiological hypertrophy and pathological remodeling.
Jia P, Wu N, Yang H, Guo Y, Guo X, Sun Y
Translational research : the journal of laboratory and clinical medicine 2021 Jul;233:47-61
Translational research : the journal of laboratory and clinical medicine 2021 Jul;233:47-61
Betulinic acid attenuated bleomycin-induced pulmonary fibrosis by effectively intervening Wnt/β-catenin signaling.
Li X, Liu X, Deng R, Gao S, Jiang Q, Liu R, Li H, Miao Y, Zhai Y, Zhang S, Wang Z, Ren Y, Ning W, Zhou H, Yang C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Jan;81:153428
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Jan;81:153428
USP15 participates in DBP-induced testicular oxidative stress injury through regulating the Keap1/Nrf2 signaling pathway.
Zhang L, Gao X, Qin Z, Shi X, Xu K, Wang S, Tang M, Wang W, Gao S, Zuo L, Zhang L, Zhang W
The Science of the total environment 2021 Aug 20;783:146898
The Science of the total environment 2021 Aug 20;783:146898
Pygo1 regulates pathological cardiac hypertrophy via a β-catenin-dependent mechanism.
Lin L, Xu W, Li Y, Zhu P, Yuan W, Liu M, Shi Y, Chen Y, Liang J, Chen J, Yang B, Cai W, Wen Y, Zhu X, Peng X, Zhou Z, Mo X, Wan Y, Yuan H, Li F, Ye X, Jiang Z, Wang Y, Zhuang J, Fan X, Wu X
American journal of physiology. Heart and circulatory physiology 2021 Apr 1;320(4):H1634-H1645
American journal of physiology. Heart and circulatory physiology 2021 Apr 1;320(4):H1634-H1645
5-Azacytidine-Induced Cardiomyocyte Differentiation of Very Small Embryonic-Like Stem Cells.
Sun X, Li H, Zhu Y, Xu P, Zuo Q, Li B, Gu X
Stem cells international 2020;2020:5162350
Stem cells international 2020;2020:5162350
Prognostic Significance and Related Mechanisms of Hexokinase 1 in Ovarian Cancer.
Li Y, Tian H, Luo H, Fu J, Jiao Y, Li Y
OncoTargets and therapy 2020;13:11583-11594
OncoTargets and therapy 2020;13:11583-11594
Evaluation of toxicity of halloysite nanotubes and multi-walled carbon nanotubes to endothelial cells in vitro and blood vessels in vivo.
Wu B, Jiang M, Liu X, Huang C, Gu Z, Cao Y
Nanotoxicology 2020 Oct;14(8):1017-1038
Nanotoxicology 2020 Oct;14(8):1017-1038
USP22 promotes proliferation in renal cell carcinoma by stabilizing survivin.
Lin Y, Zhong H, Sun B, Peng Y, Lu F, Chen M, Zhu M, Huang J
Oncology letters 2020 Nov;20(5):246
Oncology letters 2020 Nov;20(5):246
Identification of miR-515-3p and its targets, vimentin and MMP3, as a key regulatory mechanism in esophageal cancer metastasis: functional and clinical significance.
Hu HF, Xu WW, Zhang WX, Yan X, Li YJ, Li B, He QY
Signal transduction and targeted therapy 2020 Nov 27;5(1):271
Signal transduction and targeted therapy 2020 Nov 27;5(1):271
The roles of dipeptidyl peptidase-4 and its inhibitors in the regulation of airway epithelial-mesenchymal transition.
Sun J, Chu S, Lu M, Pan Q, Li D, Zheng S, Ma L
Experimental lung research 2020 May-Aug;46(6):163-173
Experimental lung research 2020 May-Aug;46(6):163-173
Ginsenoside Rg3 promotes regression from hepatic fibrosis through reducing inflammation-mediated autophagy signaling pathway.
Liu X, Mi X, Wang Z, Zhang M, Hou J, Jiang S, Wang Y, Chen C, Li W
Cell death & disease 2020 Jun 12;11(6):454
Cell death & disease 2020 Jun 12;11(6):454
AMPK decreases ERK1/2 activity and cancer cell sensitivity to nutrition deprivation by mediating a positive feedback loop involving eEF2K.
Tong S, Zhou T, Meng Y, Xu D, Chen J
Oncology letters 2020 Jul;20(1):61-66
Oncology letters 2020 Jul;20(1):61-66
Fucoxanthin inhibits hepatic oxidative stress, inflammation, and fibrosis in diet-induced nonalcoholic steatohepatitis model mice.
Takatani N, Kono Y, Beppu F, Okamatsu-Ogura Y, Yamano Y, Miyashita K, Hosokawa M
Biochemical and biophysical research communications 2020 Jul 23;528(2):305-310
Biochemical and biophysical research communications 2020 Jul 23;528(2):305-310
LINC00365-SCGB2A1 axis inhibits the viability of breast cancer through targeting NF-κB signaling.
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Biochemical and biophysical research communications 2015 Jan 2;456(1):327-32
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The Journal of biological chemistry 2015 Aug 7;290(32):19967-75
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- rat skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 23660-1-AP( ACTA1 Antibody) at dilution of 1:4000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The Alpha Actin antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human Alpha Actin. This antibody recognizes human, mouse, rat antigen. The Alpha Actin antibody has been validated for the following applications: ELISA, WB, IHC, IF analysis.