Antibody data
- Antibody Data
- Antigen structure
- References [11]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
Reference
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- Product number
- 17521-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#17521-1-AP, RRID:AB_2273608
- Product name
- ACTA1-Specific antibody
- Antibody type
- Polyclonal
- Description
- ACTA1-Specific antibody (Cat. #17521-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Novel small molecule DMAMCL induces differentiation in rhabdomyosarcoma by downregulating of DLL1.
Integrated Proteomics Unveils Nuclear PDE3A2 as a Regulator of Cardiac Myocyte Hypertrophy.
A defective mechanosensing pathway affects fibroblast-to-myofibroblast transition in the old male mouse heart.
Impaired activity of the fusogenic micropeptide Myomixer causes myopathy resembling Carey-Fineman-Ziter syndrome.
The Combination of Schisandrol B and Wedelolactone Synergistically Reverses Hepatic Fibrosis Via Modulating Multiple Signaling Pathways in Mice.
Neddylation Regulates Class IIa and III Histone Deacetylases to Mediate Myoblast Differentiation.
ACTA1 is inhibited by PAX3-FOXO1 through RhoA-MKL1-SRF signaling pathway and impairs cell proliferation, migration and tumor growth in Alveolar Rhabdomyosarcoma.
Huoxin pill prevents acute myocardial ischaemia injury via inhibition of Wnt/β-catenin signaling.
Diverging targets mediate the pathological roleof miR-199a-5p and miR-199a-3p by promoting cardiac hypertrophy and fibrosis.
Enriched environment remedies cognitive dysfunctions and synaptic plasticity through NMDAR-Ca(2+)-Activin A circuit in chronic cerebral hypoperfusion rats.
Cancer-associated fibroblasts-derived exosomal miR-17-5p promotes colorectal cancer aggressive phenotype by initiating a RUNX3/MYC/TGF-β1 positive feedback loop.
Li Q, Chen Y, Chen Y, Hua Z, Gong B, Liu Z, Thiele CJ, Li Z
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 May;174:116562
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 May;174:116562
Integrated Proteomics Unveils Nuclear PDE3A2 as a Regulator of Cardiac Myocyte Hypertrophy.
Subramaniam G, Schleicher K, Kovanich D, Zerio A, Folkmanaite M, Chao YC, Surdo NC, Koschinski A, Hu J, Scholten A, Heck AJR, Ercu M, Sholokh A, Park KC, Klussmann E, Meraviglia V, Bellin M, Zanivan S, Hester S, Mohammed S, Zaccolo M
Circulation research 2023 Mar 31;132(7):828-848
Circulation research 2023 Mar 31;132(7):828-848
A defective mechanosensing pathway affects fibroblast-to-myofibroblast transition in the old male mouse heart.
Angelini A, Trial J, Saltzman AB, Malovannaya A, Cieslik KA
iScience 2023 Aug 18;26(8):107283
iScience 2023 Aug 18;26(8):107283
Impaired activity of the fusogenic micropeptide Myomixer causes myopathy resembling Carey-Fineman-Ziter syndrome.
Ramirez-Martinez A, Zhang Y, van den Boogaard MJ, McAnally JR, Rodriguez-Caycedo C, Chai AC, Chemello F, Massink MP, Cuppen I, Elferink MG, van Es RJ, Janssen NG, Walraven-van Oijen LP, Liu N, Bassel-Duby R, van Jaarsveld RH, Olson EN
The Journal of clinical investigation 2022 Jun 1;132(11)
The Journal of clinical investigation 2022 Jun 1;132(11)
The Combination of Schisandrol B and Wedelolactone Synergistically Reverses Hepatic Fibrosis Via Modulating Multiple Signaling Pathways in Mice.
Ai Y, Shi W, Zuo X, Sun X, Chen Y, Wang Z, Li R, Song X, Dai W, Mu W, Ding K, Li Z, Li Q, Xiao X, Zhan X, Bai Z
Frontiers in pharmacology 2021;12:655531
Frontiers in pharmacology 2021;12:655531
Neddylation Regulates Class IIa and III Histone Deacetylases to Mediate Myoblast Differentiation.
Zhou H, Su H, Chen W
International journal of molecular sciences 2021 Sep 1;22(17)
International journal of molecular sciences 2021 Sep 1;22(17)
ACTA1 is inhibited by PAX3-FOXO1 through RhoA-MKL1-SRF signaling pathway and impairs cell proliferation, migration and tumor growth in Alveolar Rhabdomyosarcoma.
Hu Q, Zhu L, Li Y, Zhou J, Xu J
Cell & bioscience 2021 Jan 28;11(1):25
Cell & bioscience 2021 Jan 28;11(1):25
Huoxin pill prevents acute myocardial ischaemia injury via inhibition of Wnt/β-catenin signaling.
Wang Q, Ma E, Wo D, Chen J, He J, Peng J, Zhu W, Ren DN
Journal of cellular and molecular medicine 2021 Dec;25(24):11053-11062
Journal of cellular and molecular medicine 2021 Dec;25(24):11053-11062
Diverging targets mediate the pathological roleof miR-199a-5p and miR-199a-3p by promoting cardiac hypertrophy and fibrosis.
Zeng N, Huang YQ, Yan YM, Hu ZQ, Zhang Z, Feng JX, Guo JS, Zhu JN, Fu YH, Wang XP, Zhang MZ, Duan JZ, Zheng XL, Xu JD, Shan ZX
Molecular therapy. Nucleic acids 2021 Dec 3;26:1035-1050
Molecular therapy. Nucleic acids 2021 Dec 3;26:1035-1050
Enriched environment remedies cognitive dysfunctions and synaptic plasticity through NMDAR-Ca(2+)-Activin A circuit in chronic cerebral hypoperfusion rats.
Zhang X, Shi X, Wang J, Xu Z, He J
Aging 2021 Aug 30;13(16):20748-20761
Aging 2021 Aug 30;13(16):20748-20761
Cancer-associated fibroblasts-derived exosomal miR-17-5p promotes colorectal cancer aggressive phenotype by initiating a RUNX3/MYC/TGF-β1 positive feedback loop.
Zhang Y, Wang S, Lai Q, Fang Y, Wu C, Liu Y, Li Q, Wang X, Gu C, Chen J, Cai J, Li A, Liu S
Cancer letters 2020 Oct 28;491:22-35
Cancer letters 2020 Oct 28;491:22-35
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 17521-1-AP(ACTA1-Specific antibody) at dilution of 1:1000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The ACTA1-Specific antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human ACTA1-Specific. This antibody recognizes human,mouse,rat antigen. The ACTA1-Specific antibody has been validated for the following applications: ELISA, WB, IHC analysis.