Antibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Flow cytometry [1]
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- Product number
- FAB2014F-025 - Provider product page
- Provider
- R&D Systems
- Product name
- Human KIR2DL3/CD158b2 Fluorescein-conjugated Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects human KIR2DL3/CD158b2. Stains BaF3 cells transfected with human KIR2DL3 in flow cytometry. Does not stain BaF3 cells transfected with KIR2DL1, 2DL2, 2DL4, 2DL5, 2DS1, 2DS2, 2DS4, 3DL1, 3DL2, or 3DS1.
- Reactivity
- Human
- Host
- Mouse
- Antigen sequence
P43628
- Isotype
- IgG
- Antibody clone number
- 180701
- Vial size
- 25 Tests
- Storage
- Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied.
Submitted references Complete Remission with Reduction of High-Risk Clones following Haploidentical NK-Cell Therapy against MDS and AML.
Cutting edge: identification and characterization of human intrahepatic CD49a+ NK cells.
2DL1, 2DL2 and 2DL3 all contribute to KIR phenotype variability on human NK cells.
Modulation of the natural killer cell KIR repertoire by cytomegalovirus infection.
Molecular characterisation of KIR2DS2*005, a fusion gene associated with a shortened KIR haplotype.
Rapid expansion and long-term persistence of elevated NK cell numbers in humans infected with hantavirus.
NK cell terminal differentiation: correlated stepwise decrease of NKG2A and acquisition of KIRs.
Björklund AT, Carlsten M, Sohlberg E, Liu LL, Clancy T, Karimi M, Cooley S, Miller JS, Klimkowska M, Schaffer M, Watz E, Wikström K, Blomberg P, Wahlin BE, Palma M, Hansson L, Ljungman P, Hellström-Lindberg E, Ljunggren HG, Malmberg KJ
Clinical cancer research : an official journal of the American Association for Cancer Research 2018 Apr 15;24(8):1834-1844
Clinical cancer research : an official journal of the American Association for Cancer Research 2018 Apr 15;24(8):1834-1844
Cutting edge: identification and characterization of human intrahepatic CD49a+ NK cells.
Marquardt N, Béziat V, Nyström S, Hengst J, Ivarsson MA, Kekäläinen E, Johansson H, Mjösberg J, Westgren M, Lankisch TO, Wedemeyer H, Ellis EC, Ljunggren HG, Michaëlsson J, Björkström NK
Journal of immunology (Baltimore, Md. : 1950) 2015 Mar 15;194(6):2467-71
Journal of immunology (Baltimore, Md. : 1950) 2015 Mar 15;194(6):2467-71
2DL1, 2DL2 and 2DL3 all contribute to KIR phenotype variability on human NK cells.
Dunphy SE, Guinan KJ, Chorcora CN, Jayaraman J, Traherne JA, Trowsdale J, Pende D, Middleton D, Gardiner CM
Genes and immunity 2015 Jul-Aug;16(5):301-10
Genes and immunity 2015 Jul-Aug;16(5):301-10
Modulation of the natural killer cell KIR repertoire by cytomegalovirus infection.
Charoudeh HN, Terszowski G, Czaja K, Gonzalez A, Schmitter K, Stern M
European journal of immunology 2013 Feb;43(2):480-7
European journal of immunology 2013 Feb;43(2):480-7
Molecular characterisation of KIR2DS2*005, a fusion gene associated with a shortened KIR haplotype.
Ordóñez D, Gómez-Lozano N, Rosales L, Vilches C
Genes and immunity 2011 Oct;12(7):544-51
Genes and immunity 2011 Oct;12(7):544-51
Rapid expansion and long-term persistence of elevated NK cell numbers in humans infected with hantavirus.
Björkström NK, Lindgren T, Stoltz M, Fauriat C, Braun M, Evander M, Michaëlsson J, Malmberg KJ, Klingström J, Ahlm C, Ljunggren HG
The Journal of experimental medicine 2011 Jan 17;208(1):13-21
The Journal of experimental medicine 2011 Jan 17;208(1):13-21
NK cell terminal differentiation: correlated stepwise decrease of NKG2A and acquisition of KIRs.
Béziat V, Descours B, Parizot C, Debré P, Vieillard V
PloS one 2010 Aug 6;5(8):e11966
PloS one 2010 Aug 6;5(8):e11966
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Supportive validation
- Submitted by
- R&D Systems (provider)
- Main image
- Experimental details
- Detection of KIR2DL3/CD158b2 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human KIR2DL3/CD158b2 Fluorescein-conjugated Monoclonal Antibody (Catalog # FAB2014F) and Mouse Anti-Human NCAM-1/CD56 PE-conjugated Monoclonal Antibody (Catalog # FAB2408P). View our protocol for Staining Membrane-associated Proteins.